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Search of human proteins with 32996733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32996733 Ras association (RalGDS/AF-6) domain family 5
isoform B [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor... 693 0.0
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor... 679 0.0
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor... 277 1e-74
gi|20149588 Ras association domain family 1 isoform A [Homo sapi... 181 6e-46
gi|25777684 Ras association domain family 1 isoform D [Homo sapi... 176 3e-44
gi|25777682 Ras association domain family 1 isoform C [Homo sapi... 132 6e-31
gi|25777680 Ras association domain family 1 isoform B [Homo sapi... 117 1e-26
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3... 85 1e-16
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] 46 5e-05
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ... 46 5e-05
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens] 45 1e-04
gi|33286436 gametogenetin [Homo sapiens] 44 3e-04
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 43 5e-04
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 43 5e-04
gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens] 42 6e-04
gi|133908623 protein kinase C, iota [Homo sapiens] 42 6e-04
gi|120659787 protein kinase D2 isoform B [Homo sapiens] 42 6e-04
gi|120659785 protein kinase D2 isoform A [Homo sapiens] 42 6e-04
gi|120659782 protein kinase D2 isoform A [Homo sapiens] 42 6e-04
gi|19923468 protein kinase D2 isoform A [Homo sapiens] 42 6e-04
gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens] 42 8e-04
gi|226246586 RAS guanyl releasing protein 4 isoform g [Homo sapi... 42 8e-04
gi|226246584 RAS guanyl releasing protein 4 isoform f [Homo sapi... 42 8e-04
gi|226246581 RAS guanyl releasing protein 4 isoform e [Homo sapi... 42 8e-04
gi|226246579 RAS guanyl releasing protein 4 isoform d [Homo sapi... 42 8e-04
gi|226246577 RAS guanyl releasing protein 4 isoform c [Homo sapi... 42 8e-04
gi|226246575 RAS guanyl releasing protein 4 isoform b [Homo sapi... 42 8e-04
gi|122937247 unc-13 homolog A [Homo sapiens] 41 0.001
gi|239749251 PREDICTED: similar to hCG2042508 [Homo sapiens] 41 0.002
gi|239743343 PREDICTED: similar to hCG2042508 [Homo sapiens] 41 0.002
>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
[Homo sapiens]
Length = 336
Score = 693 bits (1789), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR 60
MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR
Sbjct: 1 MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR 60
Query: 61 SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG 120
SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG
Sbjct: 61 SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG 120
Query: 121 EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR 180
EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR
Sbjct: 121 EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR 180
Query: 181 PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI 240
PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI
Sbjct: 181 PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI 240
Query: 241 KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE 300
KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE
Sbjct: 241 KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE 300
Query: 301 VIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP 336
VIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP
Sbjct: 301 VIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP 336
>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
[Homo sapiens]
Length = 418
Score = 679 bits (1751), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR 60
MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR
Sbjct: 1 MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGR 60
Query: 61 SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG 120
SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG
Sbjct: 61 SARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG 120
Query: 121 EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR 180
EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR
Sbjct: 121 EGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDR 180
Query: 181 PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI 240
PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI
Sbjct: 181 PSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI 240
Query: 241 KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE 300
KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE
Sbjct: 241 KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSE 300
Query: 301 VIQGLLKKFMVVDNPQKFALFKRIHKDGQV 330
VIQGLLKKFMVVDNPQKFALFKRIHKDGQV
Sbjct: 301 VIQGLLKKFMVVDNPQKFALFKRIHKDGQV 330
>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
[Homo sapiens]
Length = 265
Score = 277 bits (708), Expect = 1e-74
Identities = 138/139 (99%), Positives = 139/139 (100%)
Query: 192 SQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 251
S+NVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT
Sbjct: 39 SKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 98
Query: 252 VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 311
VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV
Sbjct: 99 VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 158
Query: 312 VDNPQKFALFKRIHKDGQV 330
VDNPQKFALFKRIHKDGQV
Sbjct: 159 VDNPQKFALFKRIHKDGQV 177
>gi|20149588 Ras association domain family 1 isoform A [Homo
sapiens]
Length = 340
Score = 181 bits (460), Expect = 6e-46
Identities = 101/217 (46%), Positives = 132/217 (60%), Gaps = 17/217 (7%)
Query: 120 GEGHCFAELVLPGGPG---WCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQ 173
G GH F P GP WCDLCG V+R+ L+C +CKFTCH CR+L+ LDC
Sbjct: 49 GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGP 104
Query: 174 EGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSED 233
L + T NV +PVE + EI+QKI YN + + L M L++D
Sbjct: 105 RDLGWEPAVERDT-------NVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKD 157
Query: 234 GTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHIS 293
G+YTGFIKV LKL RPV+VP+ +P S+ DA + + +RTSFYLP DA+K LH+
Sbjct: 158 GSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVL 217
Query: 294 STTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQV 330
S T EVI+ LL+KF+VVD+P+KFALF+R + GQV
Sbjct: 218 SRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQV 254
>gi|25777684 Ras association domain family 1 isoform D [Homo
sapiens]
Length = 344
Score = 176 bits (445), Expect = 3e-44
Identities = 101/221 (45%), Positives = 132/221 (59%), Gaps = 21/221 (9%)
Query: 120 GEGHCFAELVLPGGPG---WCDLCGR---EVLRQALRCT----NCKFTCHPECRSLIQLD 169
G GH F P GP WCDLCG V+R+ L+C +CKFTCH CR+L+ LD
Sbjct: 49 GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLD 104
Query: 170 CSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMK 229
C L + T NV +PVE + EI+QKI YN + + L M
Sbjct: 105 CCGPRDLGWEPAVERDT-------NVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMS 157
Query: 230 LSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQ 289
L++DG+YTGFIKV LKL RPV+VP+ +P S+ DA + + +RTSFYLP DA+K
Sbjct: 158 LNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKH 217
Query: 290 LHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQV 330
LH+ S T EVI+ LL+KF+VVD+P+KFALF+R + GQV
Sbjct: 218 LHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQV 258
>gi|25777682 Ras association domain family 1 isoform C [Homo
sapiens]
Length = 270
Score = 132 bits (331), Expect = 6e-31
Identities = 68/134 (50%), Positives = 92/134 (68%)
Query: 197 KPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGI 256
+PVE + EI+QKI YN + + L M L++DG+YTGFIKV LKL RPV+VP+
Sbjct: 51 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK 110
Query: 257 RPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQ 316
+P S+ DA + + +RTSFYLP DA+K LH+ S T EVI+ LL+KF+VVD+P+
Sbjct: 111 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR 170
Query: 317 KFALFKRIHKDGQV 330
KFALF+R + GQV
Sbjct: 171 KFALFERAERHGQV 184
>gi|25777680 Ras association domain family 1 isoform B [Homo
sapiens]
Length = 189
Score = 117 bits (294), Expect = 1e-26
Identities = 57/103 (55%), Positives = 76/103 (73%)
Query: 228 MKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAI 287
M L++DG+YTGFIKV LKL RPV+VP+ +P S+ DA + + +RTSFYLP DA+
Sbjct: 1 MSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAV 60
Query: 288 KQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQV 330
K LH+ S T EVI+ LL+KF+VVD+P+KFALF+R + GQV
Sbjct: 61 KHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQV 103
>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
[Homo sapiens]
Length = 238
Score = 84.7 bits (208), Expect = 1e-16
Identities = 52/131 (39%), Positives = 78/131 (59%), Gaps = 20/131 (15%)
Query: 200 EETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQ 259
+ET + +EIK+K+ YN + L M L+ +G YTGFIKV ++L +P PQ
Sbjct: 43 KETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKP--------PQ 94
Query: 260 SIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFA 319
+ ++ K L+ +++ + LHISST TV EVI+ LLKKF+V ++P KFA
Sbjct: 95 TSPNSGK---LSPSSN---------GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFA 142
Query: 320 LFKRIHKDGQV 330
L+KR H++ QV
Sbjct: 143 LYKRCHREDQV 153
>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Query: 15 LLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRS-ARRAARGNLEPP 73
L L +PPR +L G PPPPP ++ + A ++ P R S +R ++RG +
Sbjct: 55 LKLPADPPR---ALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTK 111
Query: 74 PRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPG 132
P+ RP + R G + R P +PR R R+I Q P P R L PG
Sbjct: 112 PK--RPGQGRRAGARMR-SAAPASPRARAARAISNQSSPPPPPPSRARSRSL-RLSAPG 166
>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
sapiens]
Length = 274
Score = 45.8 bits (107), Expect = 5e-05
Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 8/119 (6%)
Query: 15 LLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRS-ARRAARGNLEPP 73
L L +PPR +L G PPPPP ++ + A ++ P R S +R ++RG +
Sbjct: 55 LKLPADPPR---ALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTK 111
Query: 74 PRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPG 132
P+ RP + R G + R P +PR R R+I Q P P R L PG
Sbjct: 112 PK--RPGQGRRAGARMR-SAAPASPRARAARAISNQSSPPPPPPSRARSRSL-RLSAPG 166
>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 480
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 7 AIGQRPYPLLLD--PEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARR 64
AI QRP P+ L P PPR S G PP + + P P TAP AR R R
Sbjct: 168 AIFQRP-PVYLGNKPTPPRQEGSFGGRPKSQPPLPQETAAPAPQPGPTAPPARV-REPGR 225
Query: 65 AARGNLEP--PPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERG 120
A + EP RA+RP PG R R A RP E+ PR P G
Sbjct: 226 AEGASREPRLRSRAARPPPAPGPGALSRASRSRAAGRPGPGFHGGEKAAAPRAPGGGG 283
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 9/115 (7%)
Query: 21 PPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPA 80
P R +LSGP PPPP P + +APG R A A + P P P
Sbjct: 376 PRRRAAALSGPWGSPPPP--------PEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPM 427
Query: 81 RPLRPGLQQRLRRRPGAPRPR-DVRSIFEQPQDPRVPAERGEGHCFAELVLPGGP 134
RP PGLQ+ P P P ++ P P G GH + L P
Sbjct: 428 RPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAP 482
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/112 (33%), Positives = 48/112 (42%), Gaps = 17/112 (15%)
Query: 17 LDPEPPRYLQSLSGPEL--PPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNL---E 71
L P+ P L L P+L PPPPP P APG +A AA +
Sbjct: 32 LSPQQPPLLLPLLQPQLLQPPPPPP-------PLLFLAAPGTAAAAAAAAAASSSCFSPG 84
Query: 72 PPPRASRPAR-PLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEG 122
PP R AR R G +Q+ RR P A + + R +F PQ P + G G
Sbjct: 85 PPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQ----PQQDGGG 132
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/112 (33%), Positives = 48/112 (42%), Gaps = 17/112 (15%)
Query: 17 LDPEPPRYLQSLSGPEL--PPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNL---E 71
L P+ P L L P+L PPPPP P APG +A AA +
Sbjct: 32 LSPQQPPLLLPLLQPQLLQPPPPPP-------PLLFLAAPGTAAAAAAAAAASSSCFSPG 84
Query: 72 PPPRASRPAR-PLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEG 122
PP R AR R G +Q+ RR P A + + R +F PQ P + G G
Sbjct: 85 PPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQ----PQQDGGG 132
>gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens]
Length = 592
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 94 RPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREV---LRQALR 150
+PG P P + +SI+ + R GH F +C C + RQ R
Sbjct: 102 QPGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRF-NRRAYCGQCSERIWGLARQGYR 160
Query: 151 CTNCKFTCHPECRSLIQLDC 170
C NCK H C L+ L C
Sbjct: 161 CINCKLLVHKRCHGLVPLTC 180
>gi|133908623 protein kinase C, iota [Homo sapiens]
Length = 596
Score = 42.4 bits (98), Expect = 6e-04
Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 19/167 (11%)
Query: 94 RPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVL---RQALR 150
RPG P P + +SI+ + GH F C +C + RQ +
Sbjct: 112 RPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRF-NRRAHCAICTDRIWGLGRQGYK 170
Query: 151 CTNCKFTCHPECRSLIQLDCSQQEGLSRD--RPSPESTLTVTFSQNVCKPVEETQRPPTL 208
C NCK H +C L+ ++C + L ++ P +S++ +Q V P + +L
Sbjct: 171 CINCKLLVHKKCHKLVTIECG-RHSLPQEPVMPMDQSSMHSDHAQTVI-PYNPSSH-ESL 227
Query: 209 QEIKQKIDSYNTRE----KNCLG------MKLSEDGTYTGFIKVHLK 245
++ ++ ++ NTRE + LG +++ G+Y + V LK
Sbjct: 228 DQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLK 274
>gi|120659787 protein kinase D2 isoform B [Homo sapiens]
Length = 721
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 134 PGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPEST 186
P C C + + RQ L+C +CKF CH C + + DC + ++ D P E+T
Sbjct: 118 PTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGDVPMEEAT 173
>gi|120659785 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 134 PGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPEST 186
P C C + + RQ L+C +CKF CH C + + DC + ++ D P E+T
Sbjct: 275 PTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGDVPMEEAT 330
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 134 PGWCDLCGREV---LRQALRCTNCKFTCHPECRSLIQLDCS--QQEGLSRDRPSPESTLT 188
P +CD CG + +RQ L+C C H C I +CS ++ LS + ++
Sbjct: 149 PAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVR 208
Query: 189 VTFSQNVCKPVEETQRPPT 207
+ S+++ EE R T
Sbjct: 209 LGTSESLPCTAEELSRSTT 227
>gi|120659782 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 134 PGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPEST 186
P C C + + RQ L+C +CKF CH C + + DC + ++ D P E+T
Sbjct: 275 PTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGDVPMEEAT 330
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 134 PGWCDLCGREV---LRQALRCTNCKFTCHPECRSLIQLDCS--QQEGLSRDRPSPESTLT 188
P +CD CG + +RQ L+C C H C I +CS ++ LS + ++
Sbjct: 149 PAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVR 208
Query: 189 VTFSQNVCKPVEETQRPPT 207
+ S+++ EE R T
Sbjct: 209 LGTSESLPCTAEELSRSTT 227
>gi|19923468 protein kinase D2 isoform A [Homo sapiens]
Length = 878
Score = 42.4 bits (98), Expect = 6e-04
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 134 PGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPEST 186
P C C + + RQ L+C +CKF CH C + + DC + ++ D P E+T
Sbjct: 275 PTVCQACKKLLKGLFRQGLQCKDCKFNCHKRCATRVPNDCLGEALINGDVPMEEAT 330
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 5/79 (6%)
Query: 134 PGWCDLCGREV---LRQALRCTNCKFTCHPECRSLIQLDCS--QQEGLSRDRPSPESTLT 188
P +CD CG + +RQ L+C C H C I +CS ++ LS + ++
Sbjct: 149 PAFCDHCGEMLFGLVRQGLKCDGCGLNYHKRCAFSIPNNCSGARKRRLSSTSLASGHSVR 208
Query: 189 VTFSQNVCKPVEETQRPPT 207
+ S+++ EE R T
Sbjct: 209 LGTSESLPCTAEELSRSTT 227
>gi|26051258 RAS guanyl releasing protein 4 isoform a [Homo sapiens]
Length = 673
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 541 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 599
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 600 AGPPGAPVPST 610
>gi|226246586 RAS guanyl releasing protein 4 isoform g [Homo
sapiens]
Length = 576
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 444 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 502
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 503 AGPPGAPVPST 513
>gi|226246584 RAS guanyl releasing protein 4 isoform f [Homo
sapiens]
Length = 484
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 352 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 410
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 411 AGPPGAPVPST 421
>gi|226246581 RAS guanyl releasing protein 4 isoform e [Homo
sapiens]
Length = 639
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 507 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 565
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 566 AGPPGAPVPST 576
>gi|226246579 RAS guanyl releasing protein 4 isoform d [Homo
sapiens]
Length = 604
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 472 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 530
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 531 AGPPGAPVPST 541
>gi|226246577 RAS guanyl releasing protein 4 isoform c [Homo
sapiens]
Length = 581
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 449 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 507
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 508 AGPPGAPVPST 518
>gi|226246575 RAS guanyl releasing protein 4 isoform b [Homo
sapiens]
Length = 659
Score = 42.0 bits (97), Expect = 8e-04
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 123 HCFAELVLPGGPGWCDLCGR---EVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRD 179
H F E+ P +CD C V +Q RC C CH CR ++++C ++ G D
Sbjct: 527 HTFHEVTFRK-PTFCDSCSGFLWGVTKQGYRCRECGLCCHKHCRDQVKVECKKRPGAKGD 585
Query: 180 RPSPESTLTVT 190
P + + T
Sbjct: 586 AGPPGAPVPST 596
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 144 VLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQ 203
+ RQ +RCT C CH +C+ L+ DC Q+ + E +QN+ +++
Sbjct: 665 IARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDR-----TQNIIMVLKDRM 719
Query: 204 R-----PPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIR 257
+ P + E+ Q+I + T+ + MK + G K K+ V G++
Sbjct: 720 KIRERNKPEIFELIQEIFAV-TKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQ 777
>gi|239749251 PREDICTED: similar to hCG2042508 [Homo sapiens]
Length = 460
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 23/129 (17%)
Query: 7 AIGQRPYPLLLD--PEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAR-EGRSAR 63
AI QRP P+ L P PPR S G PP + + P P TAP AR +R
Sbjct: 168 AIFQRP-PVYLGNKPTPPRQEGSFGGRPKSQPPLPQETAAPAPQPGPTAPPARPPAYESR 226
Query: 64 RAARGNLEPPPRASRPARPLR------------PGLQQRLRRRPGAPRPRDVRSIFEQPQ 111
RG E R S PA+P P + R R PG+ R R P+
Sbjct: 227 EGPRGRAE--SRGSGPAQPAHLPLPGPAHSPAPPAPELREGRAPGSTAGRRPR-----PR 279
Query: 112 DPRVPAERG 120
+P+ E G
Sbjct: 280 EPQAAEESG 288
>gi|239743343 PREDICTED: similar to hCG2042508 [Homo sapiens]
Length = 460
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 23/129 (17%)
Query: 7 AIGQRPYPLLLD--PEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAR-EGRSAR 63
AI QRP P+ L P PPR S G PP + + P P TAP AR +R
Sbjct: 168 AIFQRP-PVYLGNKPTPPRQEGSFGGRPKSQPPLPQETAAPAPQPGPTAPPARPPAYESR 226
Query: 64 RAARGNLEPPPRASRPARPLR------------PGLQQRLRRRPGAPRPRDVRSIFEQPQ 111
RG E R S PA+P P + R R PG+ R R P+
Sbjct: 227 EGPRGRAE--SRGSGPAQPAHLPLPGPAHSPAPPAPELREGRAPGSTAGRRPR-----PR 279
Query: 112 DPRVPAERG 120
+P+ E G
Sbjct: 280 EPQAAEESG 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,135,881
Number of Sequences: 37866
Number of extensions: 1077923
Number of successful extensions: 8781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 725
Number of HSP's that attempted gapping in prelim test: 6782
Number of HSP's gapped (non-prelim): 2271
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.