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Search of human proteins with 12383082
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S.
cerevisiae) [Homo sapiens]
(532 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisia... 1088 0.0
gi|223278374 DNA cross-link repair 1A [Homo sapiens] 160 4e-39
gi|76496497 artemis protein isoform a [Homo sapiens] 110 3e-24
gi|76496501 artemis protein isoform c [Homo sapiens] 62 1e-09
gi|76496499 artemis protein isoform d [Homo sapiens] 62 1e-09
gi|76496495 artemis protein isoform b [Homo sapiens] 60 4e-09
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 38 0.020
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 38 0.020
gi|153946421 endoplasmic reticulum to nucleus signalling 1 [Homo... 36 0.10
gi|66528888 Fanconi anemia complementation group D2 isoform b [H... 35 0.22
gi|21361861 Fanconi anemia complementation group D2 isoform a [H... 35 0.22
gi|6754472 kinesin family member 23 isoform 2 [Homo sapiens] 34 0.38
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 32 1.9
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 32 1.9
gi|50843827 activating molecule in beclin-1-regulated autophagy ... 30 5.5
gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo sa... 30 5.5
gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo sa... 30 5.5
gi|169203848 PREDICTED: hypothetical protein [Homo sapiens] 30 5.5
gi|7661952 squamous cell carcinoma antigen recognized by T cells... 30 7.2
gi|96304457 acid phosphatase 1, soluble isoform d [Homo sapiens] 30 7.2
gi|12056971 anaphase promoting complex subunit 1 [Homo sapiens] 30 7.2
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 30 7.2
gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens] 30 7.2
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 29 9.4
gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho... 29 9.4
gi|20143967 kinesin family member 23 isoform 1 [Homo sapiens] 29 9.4
gi|145553959 elaC homolog 2 [Homo sapiens] 29 9.4
>gi|12383082 DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
[Homo sapiens]
Length = 532
Score = 1088 bits (2813), Expect = 0.0
Identities = 532/532 (100%), Positives = 532/532 (100%)
Query: 1 MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHR 60
MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHR
Sbjct: 1 MNGVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHR 60
Query: 61 HLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEGYFGTILYTGD 120
HLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEGYFGTILYTGD
Sbjct: 61 HLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEGYFGTILYTGD 120
Query: 121 FRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIRKHPQHNIKIG 180
FRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIRKHPQHNIKIG
Sbjct: 121 FRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIRKHPQHNIKIG 180
Query: 181 LYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHS 240
LYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHS
Sbjct: 181 LYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIHAVDHMEICHS 240
Query: 241 NMLRWNQTHPTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSR 300
NMLRWNQTHPTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSR
Sbjct: 241 NMLRWNQTHPTIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSR 300
Query: 301 RPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEES 360
RPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEES
Sbjct: 301 RPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEES 360
Query: 361 ADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQK 420
ADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQK
Sbjct: 361 ADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQK 420
Query: 421 RVTMLTAPLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHG 480
RVTMLTAPLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHG
Sbjct: 421 RVTMLTAPLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHG 480
Query: 481 SPLSHSSKGTPLLATEFRGLALKYLLTPVNFFQAGYSSRRFDQQVEKYHKPC 532
SPLSHSSKGTPLLATEFRGLALKYLLTPVNFFQAGYSSRRFDQQVEKYHKPC
Sbjct: 481 SPLSHSSKGTPLLATEFRGLALKYLLTPVNFFQAGYSSRRFDQQVEKYHKPC 532
>gi|223278374 DNA cross-link repair 1A [Homo sapiens]
Length = 1040
Score = 160 bits (404), Expect = 4e-39
Identities = 111/321 (34%), Positives = 164/321 (51%), Gaps = 37/321 (11%)
Query: 6 IPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHRHLQVS 65
IP T VD + +FL+H HSDH GLS + P+YCS IT +LL L V
Sbjct: 707 IPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQ 766
Query: 66 KQWIQALEVGESHVLPLD-EIGQETMTVTLLDANHCPGSVMFLFEGYFGT-ILYTGDFRY 123
+Q+I H LPLD E + V LLDANHCPG+VM LF GT IL+TGDFR
Sbjct: 767 EQYI--------HPLPLDTECIVNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRA 818
Query: 124 TPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQE----AAHQIVQLIRKHPQHNIKI 179
PSM E +L +++H LYLD T C+P PS+QE A + + + +P +
Sbjct: 819 DPSM--ERSLLADQKVHMLYLDTTYCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVC 876
Query: 180 GLYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADV---FTVEEKAGRIHAVDHME 236
G YS+GKE + +A + V +S + + +Q L + ++ T + + +H + M+
Sbjct: 877 GTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQ 936
Query: 237 I----CHSNMLRWNQTHPTIAILPTSRKIHSS--------------HPDIHVIPYSDHSS 278
I S++ + + I + HS+ + I+ IPYS+HSS
Sbjct: 937 INFKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSS 996
Query: 279 YSELRAFVAALKPCQVVPIVS 299
Y E++ FV LKP +++P V+
Sbjct: 997 YLEMKRFVQWLKPQKIIPTVN 1017
>gi|76496497 artemis protein isoform a [Homo sapiens]
Length = 692
Score = 110 bits (275), Expect = 3e-24
Identities = 121/405 (29%), Positives = 180/405 (44%), Gaps = 65/405 (16%)
Query: 3 GVLIPHTPIAVDFWSLRRAGTARLFFLSHMHSDHTVGLSSTWARP---------LYCSPI 53
G + + I++D + R AR +FLSH H DH GL + + LYCSP+
Sbjct: 6 GQMAEYPTISIDRFD-RENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPV 64
Query: 54 TAHLL--HRHLQVSKQWIQALEVGESHVLPL-DEIG--QETMTVTLLDANHCPGSVMFLF 108
T LL + K+ I ++E+ + L DE +E + VTLL A HCPGSVMFLF
Sbjct: 65 TKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLF 124
Query: 109 EGYFGTILYTGDFRYTPSMLKEPALTLG----KQIHTLYLDNTNCNPALV-LPSRQEAAH 163
+G GT+LYTGDFR L K I ++YLD T C+P +PSR+E
Sbjct: 125 QGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLS 184
Query: 164 QIVQLIR----KHPQHNIKIGL-YSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLAD 218
+++L+R + P H + + + G E L L+ E V ++ +L++ + +
Sbjct: 185 GVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN--KLDMFRNMPEIL 242
Query: 219 VFTVEEKAGRIHAVDHMEICHSNMLRWNQTH-----------PTIAILPTSRKIHSSHPD 267
++ +IHA H + +W++ I+I P++
Sbjct: 243 HHLTTDRNTQIHACRHPKA--EEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRK 300
Query: 268 IHVIP----------YSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRISVP 317
+VI +S HSSYSE++ F++ L P P V P G D + I P
Sbjct: 301 TNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVI--PVGTTMDKV-VEILKP 357
Query: 318 LIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESAD 362
L SS S +P L +LKR RT V EE D
Sbjct: 358 LC-------RSSQSTEPKYKPL--GKLKRART---VHRDSEEEDD 390
>gi|76496501 artemis protein isoform c [Homo sapiens]
Length = 572
Score = 62.4 bits (150), Expect = 1e-09
Identities = 80/289 (27%), Positives = 122/289 (42%), Gaps = 50/289 (17%)
Query: 105 MFLFEGYFGTILYTGDFRYTPSMLKEPALTLG----KQIHTLYLDNTNCNPALV-LPSRQ 159
MFLF+G GT+LYTGDFR L K I ++YLD T C+P +PSR+
Sbjct: 1 MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSRE 60
Query: 160 EAAHQIVQLIR----KHPQHNIKIGL-YSLGKESLLEQLALEFQTWVVLSPRRLELVQLL 214
E +++L+R + P H + + + G E L L+ E V ++ +L++ + +
Sbjct: 61 ECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN--KLDMFRNM 118
Query: 215 GLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTH-----------PTIAILPTSRKIHS 263
++ +IHA H + +W++ I+I P++
Sbjct: 119 PEILHHLTTDRNTQIHACRHPKA--EEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGE 176
Query: 264 SHPDIHVIP----------YSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPR 313
+VI +S HSSYSE++ F++ L P P V P G D +
Sbjct: 177 RSRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVI--PVGTTMDKV-VE 233
Query: 314 ISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESAD 362
I PL SS S +P L +LKR RT V EE D
Sbjct: 234 ILKPLC-------RSSQSTEPKYKPL--GKLKRART---VHRDSEEEDD 270
>gi|76496499 artemis protein isoform d [Homo sapiens]
Length = 572
Score = 62.4 bits (150), Expect = 1e-09
Identities = 80/289 (27%), Positives = 122/289 (42%), Gaps = 50/289 (17%)
Query: 105 MFLFEGYFGTILYTGDFRYTPSMLKEPALTLG----KQIHTLYLDNTNCNPALV-LPSRQ 159
MFLF+G GT+LYTGDFR L K I ++YLD T C+P +PSR+
Sbjct: 1 MFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSRE 60
Query: 160 EAAHQIVQLIR----KHPQHNIKIGL-YSLGKESLLEQLALEFQTWVVLSPRRLELVQLL 214
E +++L+R + P H + + + G E L L+ E V ++ +L++ + +
Sbjct: 61 ECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN--KLDMFRNM 118
Query: 215 GLADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTH-----------PTIAILPTSRKIHS 263
++ +IHA H + +W++ I+I P++
Sbjct: 119 PEILHHLTTDRNTQIHACRHPKA--EEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGE 176
Query: 264 SHPDIHVIP----------YSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPR 313
+VI +S HSSYSE++ F++ L P P V P G D +
Sbjct: 177 RSRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVI--PVGTTMDKV-VE 233
Query: 314 ISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESAD 362
I PL SS S +P L +LKR RT V EE D
Sbjct: 234 ILKPLC-------RSSQSTEPKYKPL--GKLKRART---VHRDSEEEDD 270
>gi|76496495 artemis protein isoform b [Homo sapiens]
Length = 577
Score = 60.5 bits (145), Expect = 4e-09
Identities = 79/288 (27%), Positives = 121/288 (42%), Gaps = 50/288 (17%)
Query: 106 FLFEGYFGTILYTGDFRYTPSMLKEPALTLG----KQIHTLYLDNTNCNPALV-LPSRQE 160
FLF+G GT+LYTGDFR L K I ++YLD T C+P +PSR+E
Sbjct: 7 FLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREE 66
Query: 161 AAHQIVQLIR----KHPQHNIKIGL-YSLGKESLLEQLALEFQTWVVLSPRRLELVQLLG 215
+++L+R + P H + + + G E L L+ E V ++ +L++ + +
Sbjct: 67 CLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVN--KLDMFRNMP 124
Query: 216 LADVFTVEEKAGRIHAVDHMEICHSNMLRWNQTH-----------PTIAILPTSRKIHSS 264
++ +IHA H + +W++ I+I P++
Sbjct: 125 EILHHLTTDRNTQIHACRHPKA--EEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGER 182
Query: 265 HPDIHVIP----------YSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRI 314
+VI +S HSSYSE++ F++ L P P V P G D + I
Sbjct: 183 SRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVI--PVGTTMDKV-VEI 239
Query: 315 SVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESAD 362
PL SS S +P L +LKR RT V EE D
Sbjct: 240 LKPLC-------RSSQSTEPKYKPL--GKLKRART---VHRDSEEEDD 275
>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
Length = 2540
Score = 38.1 bits (87), Expect = 0.020
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 11/116 (9%)
Query: 251 TIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSL 310
T+ +P + HP IH SYS +L P + P++ G Q+S
Sbjct: 1196 TLRSMPALHRAPVFHPPIHHSLERKEGSYS-------SLSPPTLTPVMPVNAGGKVQESQ 1248
Query: 311 SPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQA 366
P +P DS + SSS + + +W L + +T+ V E+S+ + QA
Sbjct: 1249 KPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHV----EKSSGKLQA 1300
>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
Length = 2303
Score = 38.1 bits (87), Expect = 0.020
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 11/116 (9%)
Query: 251 TIAILPTSRKIHSSHPDIHVIPYSDHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSL 310
T+ +P + HP IH SYS +L P + P++ G Q+S
Sbjct: 977 TLRSMPALHRAPVFHPPIHHSLERKEGSYS-------SLSPPTLTPVMPVNAGGKVQESQ 1029
Query: 311 SPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQA 366
P +P DS + SSS + + +W L + +T+ V E+S+ + QA
Sbjct: 1030 KPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHV----EKSSGKLQA 1081
>gi|153946421 endoplasmic reticulum to nucleus signalling 1 [Homo
sapiens]
Length = 977
Score = 35.8 bits (81), Expect = 0.10
Identities = 43/192 (22%), Positives = 72/192 (37%), Gaps = 27/192 (14%)
Query: 51 SPITAHLLHRHLQVSKQWIQALEVGESHVLPLDEIGQETMTVTLLDANHCPGSVMFLFEG 110
SP T+ H S A + G S L D+ +ET V + + CP V L G
Sbjct: 525 SPSTSPRASNHSLCSGS--SASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDV--LGHG 580
Query: 111 YFGTILYTGDFRYTPSMLKEPALTLGKQIHTLYLDNTNCNPALVLPSRQEAAHQIVQLIR 170
GTI+Y G F DN + +LP A + VQL+R
Sbjct: 581 AEGTIVYRGMF-----------------------DNRDVAVKRILPECFSFADREVQLLR 617
Query: 171 KHPQHNIKIGLYSLGKESLLEQLALEFQTWVVLSPRRLELVQLLGLADVFTVEEKAGRIH 230
+ +H I + K+ + +A+E + + LGL + +++ +
Sbjct: 618 ESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLA 677
Query: 231 AVDHMEICHSNM 242
+ + I H ++
Sbjct: 678 HLHSLNIVHRDL 689
>gi|66528888 Fanconi anemia complementation group D2 isoform b [Homo
sapiens]
Length = 1451
Score = 34.7 bits (78), Expect = 0.22
Identities = 40/173 (23%), Positives = 68/173 (39%), Gaps = 29/173 (16%)
Query: 231 AVDHMEICHSNMLRWNQTHPTIAILPTSRKIHSSHPDIHV----------------IPYS 274
A D +I +L WN +IL K+ SHP +HV +P
Sbjct: 1254 AADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEAFLKQCMPLL 1313
Query: 275 DHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRIS--VPLIPDSVQ------QY 326
D S ++ L+ Q+ + CG + R++ VPL+ +++ +
Sbjct: 1314 DFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKA 1373
Query: 327 MSSSSRKPSLLWLLERRLKRPRTQGVVFE---SPEESADQSQADRDSKKAKKE 376
M + + WL LK QG + S E +AD+S+ D S+ +K +
Sbjct: 1374 MLTLNNCREAFWL--GNLKNRDLQGEEIKSQNSQESTADESEDDMSSQASKSK 1424
>gi|21361861 Fanconi anemia complementation group D2 isoform a [Homo
sapiens]
Length = 1471
Score = 34.7 bits (78), Expect = 0.22
Identities = 40/173 (23%), Positives = 68/173 (39%), Gaps = 29/173 (16%)
Query: 231 AVDHMEICHSNMLRWNQTHPTIAILPTSRKIHSSHPDIHV----------------IPYS 274
A D +I +L WN +IL K+ SHP +HV +P
Sbjct: 1254 AADSQQIHEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEAFLKQCMPLL 1313
Query: 275 DHSSYSELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRIS--VPLIPDSVQ------QY 326
D S ++ L+ Q+ + CG + R++ VPL+ +++ +
Sbjct: 1314 DFSFRKHREDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKA 1373
Query: 327 MSSSSRKPSLLWLLERRLKRPRTQGVVFE---SPEESADQSQADRDSKKAKKE 376
M + + WL LK QG + S E +AD+S+ D S+ +K +
Sbjct: 1374 MLTLNNCREAFWL--GNLKNRDLQGEEIKSQNSQESTADESEDDMSSQASKSK 1424
>gi|6754472 kinesin family member 23 isoform 2 [Homo sapiens]
Length = 856
Score = 33.9 bits (76), Expect = 0.38
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 337 LWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHH--PL 394
LW+ + +LK+ + +V E E ++ +RD +K + +SP P L QP + P+
Sbjct: 644 LWVKDEKLKQ--LKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPLLFQPDQNAPPI 701
Query: 395 RIK 397
R++
Sbjct: 702 RLR 704
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/153 (22%), Positives = 60/153 (39%), Gaps = 19/153 (12%)
Query: 328 SSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEK 387
+SS ++ + L ERR + +S S+D ++ D+KK K+ S A + K
Sbjct: 1085 NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVK 1144
Query: 388 QPSHHPLR---------IKKQLFPDLYSKEWNKAVPFCESQKRVTMLTAPLGFSVH---L 435
+ + LR I D+ + N ++++ +T L S H
Sbjct: 1145 EKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFC 1204
Query: 436 RSTDEEFISQKTREEIGLGSPLVPMGDDDGGPE 468
+S+ +E +S+ V DDD PE
Sbjct: 1205 QSSGDEALSKSV-------PVTVDDDDDDNDPE 1230
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/153 (22%), Positives = 60/153 (39%), Gaps = 19/153 (12%)
Query: 328 SSSSRKPSLLWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEK 387
+SS ++ + L ERR + +S S+D ++ D+KK K+ S A + K
Sbjct: 1123 NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVK 1182
Query: 388 QPSHHPLR---------IKKQLFPDLYSKEWNKAVPFCESQKRVTMLTAPLGFSVH---L 435
+ + LR I D+ + N ++++ +T L S H
Sbjct: 1183 EKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFC 1242
Query: 436 RSTDEEFISQKTREEIGLGSPLVPMGDDDGGPE 468
+S+ +E +S+ V DDD PE
Sbjct: 1243 QSSGDEALSKSV-------PVTVDDDDDDNDPE 1268
>gi|50843827 activating molecule in beclin-1-regulated autophagy
[Homo sapiens]
Length = 1208
Score = 30.0 bits (66), Expect = 5.5
Identities = 26/107 (24%), Positives = 36/107 (33%), Gaps = 19/107 (17%)
Query: 378 LSPWPADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQKRVTMLTAPLGFSVHLRS 437
L P L S HP R +++ P L EW + V S+ + P
Sbjct: 298 LGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPP--------- 348
Query: 438 TDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHGSPLS 484
R S L + +GG +A+ SA G G P S
Sbjct: 349 ----------RTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPAS 385
>gi|169204941 PREDICTED: similar to Nucleolar protein 5A [Homo
sapiens]
Length = 166
Score = 30.0 bits (66), Expect = 5.5
Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 6/63 (9%)
Query: 339 LLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKK 398
LL+R+ P+T+ V PEE+ ++S + + +K +K+E +S P + S KK
Sbjct: 103 LLKRKKSSPKTETV--NDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSS----KK 156
Query: 399 QLF 401
++F
Sbjct: 157 KMF 159
>gi|169205573 PREDICTED: similar to Nucleolar protein 5A [Homo
sapiens]
Length = 166
Score = 30.0 bits (66), Expect = 5.5
Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 6/63 (9%)
Query: 339 LLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKK 398
LL+R+ P+T+ V PEE+ ++S + + +K +K+E +S P + S KK
Sbjct: 103 LLKRKKSSPKTETV--NDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSS----KK 156
Query: 399 QLF 401
++F
Sbjct: 157 KMF 159
>gi|169203848 PREDICTED: hypothetical protein [Homo sapiens]
Length = 166
Score = 30.0 bits (66), Expect = 5.5
Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 6/63 (9%)
Query: 339 LLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADLEKQPSHHPLRIKK 398
LL+R+ P+T+ V PEE+ ++S + + +K +K+E +S P + S KK
Sbjct: 103 LLKRKKSSPKTETV--NDPEEAGNRSVSKKKTKFSKEEPVSSGPEEAAGSKSSS----KK 156
Query: 399 QLF 401
++F
Sbjct: 157 KMF 159
>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
[Homo sapiens]
Length = 963
Score = 29.6 bits (65), Expect = 7.2
Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 15/65 (23%)
Query: 341 ERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKL---------------SPWPADL 385
E+R+K + + + EE A+Q + R KKA K+K W D
Sbjct: 578 EQRMKAAEKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDE 637
Query: 386 EKQPS 390
E+QPS
Sbjct: 638 EEQPS 642
>gi|96304457 acid phosphatase 1, soluble isoform d [Homo sapiens]
Length = 112
Score = 29.6 bits (65), Expect = 7.2
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 427 APLGFSVHLRSTDEEFISQKTREEIGLGSPLVPMGDDDGGPEATGNQSAWMGHGSPLSHS 486
+P+ +V + ++ IS+ R + S G + G P QS HG P+SH
Sbjct: 20 SPIAEAVFRKLVTDQNISENWRVDSAATS-----GYEIGNPPDYRGQSCMKRHGIPMSHV 74
Query: 487 SKGTPLLATEFRGLALKYLLTPVNF 511
++ P L + L LT V F
Sbjct: 75 ARQVPSLDLKLCVLCFSGSLTAVLF 99
>gi|12056971 anaphase promoting complex subunit 1 [Homo sapiens]
Length = 1944
Score = 29.6 bits (65), Expect = 7.2
Identities = 12/36 (33%), Positives = 24/36 (66%)
Query: 177 IKIGLYSLGKESLLEQLALEFQTWVVLSPRRLELVQ 212
+ I LY LG ESL+ + ++ T + ++P++L++ Q
Sbjct: 875 LSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ 910
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 29.6 bits (65), Expect = 7.2
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 13/96 (13%)
Query: 287 AALKPCQVVPIVSRRPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLLERRLKR 346
AA P P V R Q SL+P PLIP +S K +W L R R
Sbjct: 492 AARTPQSPAPCVLLRA----QRSLAPEPKEPLIP---------ASPKAEPIWELPTRAPR 538
Query: 347 PRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWP 382
+ F E DQ + +S +A K+ +P P
Sbjct: 539 LSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSP 574
>gi|153251913 hypothetical protein LOC57604 isoform 1 [Homo sapiens]
Length = 454
Score = 29.6 bits (65), Expect = 7.2
Identities = 15/38 (39%), Positives = 18/38 (47%)
Query: 383 ADLEKQPSHHPLRIKKQLFPDLYSKEWNKAVPFCESQK 420
A LEKQ H+ F DL SK W + F + QK
Sbjct: 6 AQLEKQHVHNVYESTAPYFSDLQSKAWPRVRQFLQEQK 43
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 29.3 bits (64), Expect = 9.4
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 14/83 (16%)
Query: 236 EICHSNMLRWNQTHPTIAIL--------PTSRKI-HSSHPDIHVI-----PYSDHSSYSE 281
E H MLR HP + L P S + SH D+H P+SD S +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 282 LRAFVAALKPCQVVPIVSRRPCG 304
R +AL+P V +V++ G
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAG 602
>gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo
sapiens]
Length = 1288
Score = 29.3 bits (64), Expect = 9.4
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 21/126 (16%)
Query: 281 ELRAFVAALKPCQVVPIVSRRPCGGFQDSLSPRISVPLIPDSVQQYMSSSSRKPSLLWLL 340
ELRA L+ + P + RP F PD+V+Q + +P +++L
Sbjct: 1058 ELRALQGRLRAQGLGPALLHRPLFAF-------------PDAVKQILRKRQIRPHWMFVL 1104
Query: 341 ERRLKRP--RTQGVVFESPEESADQSQADRDSKKAKKE----KLSPWPADLEKQPSHHPL 394
+ L R GV+ E+ A +++ S + + + SP P + E+ P+ PL
Sbjct: 1105 DSLLSRAVRAALGVLGPEVEKEAVSPRSEELSNEGDSQQSPGQQSPLPVEPEQGPA--PL 1162
Query: 395 RIKKQL 400
++ L
Sbjct: 1163 MVQLSL 1168
>gi|20143967 kinesin family member 23 isoform 1 [Homo sapiens]
Length = 960
Score = 29.3 bits (64), Expect = 9.4
Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 337 LWLLERRLKRPRTQGVVFESPEESADQSQADRDSKKAKKEKLSPWPADL 385
LW+ + +LK+ + +V E E ++ +RD +K + +SP P L
Sbjct: 644 LWVKDEKLKQ--LKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPL 690
>gi|145553959 elaC homolog 2 [Homo sapiens]
Length = 826
Score = 29.3 bits (64), Expect = 9.4
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 4/56 (7%)
Query: 19 RRAGTARLFFLSHMHSDHTVGLSSTWARPLYCSPITAHLLHRHLQVS----KQWIQ 70
R GT F+SH+H+DH GL S + LH L V+ K W+Q
Sbjct: 534 RVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQ 589
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,826,101
Number of Sequences: 37866
Number of extensions: 1062641
Number of successful extensions: 3039
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3000
Number of HSP's gapped (non-prelim): 35
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.