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Search of human proteins with 32698815
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 760 0.0
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 668 0.0
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 655 0.0
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 144 2e-34
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 137 2e-32
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 133 2e-31
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 133 2e-31
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 133 2e-31
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 124 2e-28
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 123 3e-28
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 120 3e-27
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 119 6e-27
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 119 6e-27
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 119 6e-27
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 112 5e-25
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 112 5e-25
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 110 2e-24
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 109 3e-24
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 109 3e-24
gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17... 105 8e-23
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 104 1e-22
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 104 1e-22
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 104 1e-22
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 104 1e-22
gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ... 104 1e-22
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 103 2e-22
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 103 2e-22
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 103 2e-22
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 103 2e-22
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 103 2e-22
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 760 bits (1963), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFC 60
MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFC
Sbjct: 1 MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFC 60
Query: 61 RPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNY 120
RPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNY
Sbjct: 61 RPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNY 120
Query: 121 MQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTL 180
MQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTL
Sbjct: 121 MQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTL 180
Query: 181 TNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQ 240
TNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQ
Sbjct: 181 TNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQ 240
Query: 241 EAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMY 300
EAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMY
Sbjct: 241 EAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMY 300
Query: 301 DLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 360
DLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES
Sbjct: 301 DLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 360
Query: 361 GYILFYQSRD 370
GYILFYQSRD
Sbjct: 361 GYILFYQSRD 370
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 668 bits (1723), Expect = 0.0
Identities = 323/366 (88%), Positives = 340/366 (92%)
Query: 5 MTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFR 64
MTV ASIC MG NASALEK+IGPEQFP+NEHYFGLVNFGNTCYCNSVLQALYFCRPFR
Sbjct: 1 MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR 60
Query: 65 EKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQD 124
E VLAYK+Q +KKE+LLTCLADLFHSIATQKKKVGVIPPKKFI+RLRKEN+LFDNYMQQD
Sbjct: 61 ENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQD 120
Query: 125 AHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNET 184
AHEFLNYLLNTIADILQEE+KQEKQNG+L NGN++ N+ P+ TWV EIFQGTLTNET
Sbjct: 121 AHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNET 180
Query: 185 RCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHK 244
RCL CET+SSKDEDFLDLSVDVEQNTSITHCLR FSNTETLCSE KYYCE C SKQEA K
Sbjct: 181 RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 240
Query: 245 RMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVA 304
RM+VKKLPMILALHLKRFKYM+QLHRYTKLSYRVVFPLELRLFNTS DA N DRMYDLVA
Sbjct: 241 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVA 300
Query: 305 VVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 364
VVVHCGSGPNRGHYI IVKSH FWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL
Sbjct: 301 VVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYIL 360
Query: 365 FYQSRD 370
FYQSR+
Sbjct: 361 FYQSRE 366
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 655 bits (1691), Expect = 0.0
Identities = 316/357 (88%), Positives = 333/357 (93%)
Query: 14 CTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQ 73
C G NASALEK+IGPEQFP+NEHYFGLVNFGNTCYCNSVLQALYFCRPFRE VLAYK+Q
Sbjct: 3 CFQGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQ 62
Query: 74 PRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLL 133
+KKE+LLTCLADLFHSIATQKKKVGVIPPKKFI+RLRKEN+LFDNYMQQDAHEFLNYLL
Sbjct: 63 QKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 122
Query: 134 NTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETIS 193
NTIADILQEE+KQEKQNG+L NGN++ N+ P+ TWV EIFQGTLTNETRCL CET+S
Sbjct: 123 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVS 182
Query: 194 SKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253
SKDEDFLDLSVDVEQNTSITHCLR FSNTETLCSE KYYCE C SKQEA KRM+VKKLPM
Sbjct: 183 SKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM 242
Query: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGP 313
ILALHLKRFKYM+QLHRYTKLSYRVVFPLELRLFNTS DA N DRMYDLVAVVVHCGSGP
Sbjct: 243 ILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGP 302
Query: 314 NRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD 370
NRGHYI IVKSH FWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR+
Sbjct: 303 NRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 359
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 144 bits (362), Expect = 2e-34
Identities = 115/369 (31%), Positives = 163/369 (44%), Gaps = 62/369 (16%)
Query: 40 GLVNFGNTCYCNSVLQAL----YFCRPFRE--------------KVLAYKSQPRKKESLL 81
GL N GNTC+ N++LQ+L FC F+E + +SQ SL+
Sbjct: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
Query: 82 T----CLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIA 137
L L+ T P+ + K F Y QQDAHEF+ YLL+ +
Sbjct: 220 EEFRKTLCALWQGSQT------AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLH 273
Query: 138 DILQEERKQEKQNGRLPNGNIDNENNNSTPD--PTWVDEIFQGTLTNETRCLTCETISSK 195
LQ ++ L + + +N + T V IF G L NE CL C T S K
Sbjct: 274 LELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRK 333
Query: 196 DEDFLDLSVDVEQN--------------TSITHCLRGFSNTETLCSEYKYYCEECRSKQE 241
+ FLDLS+D+ S+ CLR F++ E L Y C +C+ KQ+
Sbjct: 334 FDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQK 393
Query: 242 AHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFP---LELRLFNTSGDATNPDR 298
+ K+ ++KLP +L LHLKRF + L K+ V FP L+++ + + + P+
Sbjct: 394 STKKFWIQKLPKVLCLHLKRFHWTAYLR--NKVDTYVEFPLRGLDMKCYLLEPENSGPES 451
Query: 299 -MYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKN 357
+YDL AVVVH GSG GHY A W F+D V D + + +
Sbjct: 452 CLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVK----------- 500
Query: 358 SESGYILFY 366
YILFY
Sbjct: 501 -AKAYILFY 508
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 137 bits (345), Expect = 2e-32
Identities = 108/374 (28%), Positives = 164/374 (43%), Gaps = 74/374 (19%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTC-LADLFHSIATQKK 96
GL+N GNTC+ N ++QAL R+ L+ ++ + + S L C ++ LF + +
Sbjct: 177 GLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHR 236
Query: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156
+ P K + + Y QQDAHEFL L D+L K + + N
Sbjct: 237 SPHI--PYKLLHLVWTHARHLAGYEQQDAHEFLIAAL----DVLHRHCKGDDNGKKANNP 290
Query: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVD----------- 205
N N +D+IF G L ++ C C +S+ + F D+S+D
Sbjct: 291 NHCN---------CIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPL 341
Query: 206 --------------VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKL 251
V T++T CLR F+ E L S K C C S QE+ K++ +KKL
Sbjct: 342 SPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKL 401
Query: 252 PMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL---------------FNTSGDATNP 296
P++ HLKRF++ +L R K++ V FPLEL + + D+ N
Sbjct: 402 PIVACFHLKRFEHSAKLRR--KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNN 459
Query: 297 DRMYDLVAVVVHCGSGPNRGHYIAIVKSH-DFWLLFDDDIVEKIDAQAIEEFYGLTSDIS 355
D Y L AVV H G+ GHY + ++ H D W DD I+ K + + +
Sbjct: 460 DNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD--------- 509
Query: 356 KNSESGYILFYQSR 369
GY+LFY +
Sbjct: 510 ---SEGYLLFYHKQ 520
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 133 bits (335), Expect = 2e-31
Identities = 110/358 (30%), Positives = 162/358 (45%), Gaps = 56/358 (15%)
Query: 40 GLVNFGNTCYCNSVLQAL--------YFCRPF------REKVLAYKSQPRKKESLLTCLA 85
GL N GNTCY NS+LQ L YF R R +L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 86 DLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
A + I PK F + K N+ F Y QQD+ E L +L+ D L E+
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLM----DGLHEDLN 885
Query: 146 QEKQNGRLPNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSK 195
+ R N D+ ++ + W + +FQG + +CLTC S
Sbjct: 886 KADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945
Query: 196 DEDFLDLSVDVEQNTSIT--HCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253
E F+ LS+ + + T CLR FS E L ++YC CR+++++ K++++ KLP
Sbjct: 946 FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPP 1005
Query: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDLVAVVVHCGSG 312
+L +HLKRF Y + + KL V FPLE L L N + Y+L +V H G G
Sbjct: 1006 VLLVHLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-G 1062
Query: 313 PNRGHYIAIVK--SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 368
+ GHY A K + W FDD V I +++ S + YILFY S
Sbjct: 1063 LDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 133 bits (335), Expect = 2e-31
Identities = 110/358 (30%), Positives = 162/358 (45%), Gaps = 56/358 (15%)
Query: 40 GLVNFGNTCYCNSVLQAL--------YFCRPF------REKVLAYKSQPRKKESLLTCLA 85
GL N GNTCY NS+LQ L YF R R +L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 86 DLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
A + I PK F + K N+ F Y QQD+ E L +L+ D L E+
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLM----DGLHEDLN 885
Query: 146 QEKQNGRLPNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSK 195
+ R N D+ ++ + W + +FQG + +CLTC S
Sbjct: 886 KADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945
Query: 196 DEDFLDLSVDVEQNTSIT--HCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253
E F+ LS+ + + T CLR FS E L ++YC CR+++++ K++++ KLP
Sbjct: 946 FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPP 1005
Query: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDLVAVVVHCGSG 312
+L +HLKRF Y + + KL V FPLE L L N + Y+L +V H G G
Sbjct: 1006 VLLVHLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-G 1062
Query: 313 PNRGHYIAIVK--SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 368
+ GHY A K + W FDD V I +++ S + YILFY S
Sbjct: 1063 LDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 133 bits (335), Expect = 2e-31
Identities = 110/358 (30%), Positives = 162/358 (45%), Gaps = 56/358 (15%)
Query: 40 GLVNFGNTCYCNSVLQAL--------YFCRPF------REKVLAYKSQPRKKESLLTCLA 85
GL N GNTCY NS+LQ L YF R R +L +K + ++ ++
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
Query: 86 DLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
A + I PK F + K N+ F Y QQD+ E L +L+ D L E+
Sbjct: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLM----DGLHEDLN 885
Query: 146 QEKQNGRLPNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSK 195
+ R N D+ ++ + W + +FQG + +CLTC S
Sbjct: 886 KADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945
Query: 196 DEDFLDLSVDVEQNTSIT--HCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253
E F+ LS+ + + T CLR FS E L ++YC CR+++++ K++++ KLP
Sbjct: 946 FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPP 1005
Query: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDLVAVVVHCGSG 312
+L +HLKRF Y + + KL V FPLE L L N + Y+L +V H G G
Sbjct: 1006 VLLVHLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-G 1062
Query: 313 PNRGHYIAIVK--SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 368
+ GHY A K + W FDD V I +++ S + YILFY S
Sbjct: 1063 LDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 124 bits (310), Expect = 2e-28
Identities = 104/373 (27%), Positives = 163/373 (43%), Gaps = 73/373 (19%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTC-LADLFHSIATQKK 96
GL+N GNTC+ N ++QAL ++ L+ +K L C ++ LFH++ + +
Sbjct: 364 GLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLCLVCEMSSLFHAMYSGSR 423
Query: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156
+ P K + + E Y QQDAHEFL +L D+L K + N
Sbjct: 424 TPHI--PYKLLHLIWIHAEHLAGYRQQDAHEFLIAIL----DVLHRHSKDDSGGQEANNP 477
Query: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV--------EQ 208
N N +D+IF G L ++ C C ++S+ + D+S+D+ Q
Sbjct: 478 NCCN---------CIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQ 528
Query: 209 NT-----------------SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKL 251
N S+T CL+ F+ E L S K C C+S QE+ K++ +KKL
Sbjct: 529 NPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKL 588
Query: 252 PMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLF--------------NTSGDATNPD 297
P++ HLKRF+++ + R K++ + FPLEL + D +
Sbjct: 589 PIVACFHLKRFEHVGKQRR--KINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNE 646
Query: 298 RMYDLVAVVVHCGSGPNRGHYIAIVKSH-DFWLLFDDDIVEKIDAQAIEEFYGLTSDISK 356
Y L AV+ H G+ GHY + ++ D W DD I+ K IE+
Sbjct: 647 NKYSLFAVINHHGT-LESGHYTSFIRQQKDQWFSCDDAIITK---ATIEDLL-------- 694
Query: 357 NSESGYILFYQSR 369
GY+LFY +
Sbjct: 695 -YSEGYLLFYHKQ 706
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 123 bits (308), Expect = 3e-28
Identities = 98/337 (29%), Positives = 147/337 (43%), Gaps = 49/337 (14%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKV- 98
GL N GNTC+ N+ LQ L + P +L++ E TC A+ F + T + +
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSH-------EHSKTCHAEGFCMMCTMQAHIT 164
Query: 99 -------GVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNG 151
VI P I +R+ F Q+DAHEFL Y ++ + Q
Sbjct: 165 QALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAM------------QKA 212
Query: 152 RLPNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTS 211
L N N+ + T T V +IF G L + +CL C+ +S + +LD++++++ S
Sbjct: 213 CL---NGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQS 269
Query: 212 ITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRY 271
+ L F E L E Y C +C+ A KR + + +L L LKRF
Sbjct: 270 VNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTG---- 325
Query: 272 TKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVK-SHDFWLL 330
K++ V +P L + +Y L AV+VH G + GHY +K S+ W
Sbjct: 326 GKIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQ 385
Query: 331 FDDDIVEKIDAQAIEEFYGLTSDI-SKNSESGYILFY 366
+D IV TSDI S S+ Y+LFY
Sbjct: 386 MNDSIVS-------------TSDIRSVLSQQAYVLFY 409
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 120 bits (300), Expect = 3e-27
Identities = 101/373 (27%), Positives = 162/373 (43%), Gaps = 73/373 (19%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTC-LADLFHSIATQKK 96
GL+N GNTC+ N ++QAL R+ L+ ++ + E L C ++ LF + +
Sbjct: 79 GLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSSLFRELYSGNP 138
Query: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156
V P K + + Y QQDAHEFL L D+L K +
Sbjct: 139 SPHV--PYKLLHLVWIHARHLAGYRQQDAHEFLIAAL----DVLHRHCKGD--------- 183
Query: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN------- 209
++ NN +D+IF G L ++ C C +S+ + D+S+D+ +
Sbjct: 184 DVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPM 243
Query: 210 -----------------TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLP 252
T++T CLR F+ E L S K C C+S QE+ K++ + KLP
Sbjct: 244 SPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLP 303
Query: 253 MILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--FNTSG-------------DATNPD 297
++ H KRF++ + R K++ + FPLEL + F S ++ N +
Sbjct: 304 VVACFHFKRFEHSAKQRR--KITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNE 361
Query: 298 RMYDLVAVVVHCGSGPNRGHYIAIVKSH-DFWLLFDDDIVEKIDAQAIEEFYGLTSDISK 356
Y L AVV H G+ GHY + ++ H D W DD ++ K + + +
Sbjct: 362 NKYSLFAVVNHQGT-LESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLD---------- 410
Query: 357 NSESGYILFYQSR 369
GY+LFY +
Sbjct: 411 --SEGYLLFYHKQ 421
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 119 bits (297), Expect = 6e-27
Identities = 90/331 (27%), Positives = 141/331 (42%), Gaps = 37/331 (11%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLF--HSIATQKKK 97
GL N GNTC+ N+ +Q L + P +L+ K R C+ + H +
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLS-KEHARSCHQGSFCMLCVMQNHIVQAFANS 181
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADI-LQEERKQEKQNGRLPNG 156
I P FI L+K F Q+DAHEFL Y ++ + L K ++Q
Sbjct: 182 GNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQ------- 234
Query: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCL 216
T T V +IF G L + +C C+++S + +LD+++++ Q +I L
Sbjct: 235 ---------TQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRAL 285
Query: 217 RGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSY 276
F + L E Y C +C+ K A KR + + +L L LKRF K++
Sbjct: 286 ELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSG----GKITK 341
Query: 277 RVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVK-SHDFWLLFDDDI 335
V +P L + MY L AV+VH G + GHY VK S+ W +D +
Sbjct: 342 DVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSL 401
Query: 336 VEKIDAQAIEEFYGLTSDISKNSESGYILFY 366
V + + + ++ Y+LFY
Sbjct: 402 VHSSNVKVV------------LNQQAYVLFY 420
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 119 bits (297), Expect = 6e-27
Identities = 103/351 (29%), Positives = 161/351 (45%), Gaps = 44/351 (12%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCL----ADLFHSIAT 93
GL N GNTC+ NS+LQ L R R+ L Y + T L A L +I T
Sbjct: 59 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 118
Query: 94 QKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRL 153
V+ P +F T++++ F Y QQDA EFL +LL+ + + + + K N
Sbjct: 119 SSPN-DVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE- 176
Query: 154 PNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSKDEDFLDLS 203
N+D+ ++ W + ++F G L + C C S+ + F DLS
Sbjct: 177 ---NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 233
Query: 204 VDVEQN----TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHL 259
+ + + ++ C+R F+ + L + K C CR ++ K+ +++ P IL LHL
Sbjct: 234 LPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHL 293
Query: 260 KRFKYMDQLHRYTKLSYRVVFPL-ELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHY 318
KRF + R +KL+ V FPL +L L + + TN +Y+L AV H G+ GHY
Sbjct: 294 KRFS--ESRIRTSKLTTFVNFPLRDLDLREFASENTN-HAVYNLYAVSNHSGTTMG-GHY 349
Query: 319 IAIVKSHDF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 367
A +S W F+D V + + + TSD Y+LFY+
Sbjct: 350 TAYCRSPGTGEWHTFNDSSVTPMSSSQVR-----TSD-------AYLLFYE 388
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 119 bits (297), Expect = 6e-27
Identities = 103/351 (29%), Positives = 161/351 (45%), Gaps = 44/351 (12%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCL----ADLFHSIAT 93
GL N GNTC+ NS+LQ L R R+ L Y + T L A L +I T
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWT 327
Query: 94 QKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRL 153
V+ P +F T++++ F Y QQDA EFL +LL+ + + + + K N
Sbjct: 328 SSPN-DVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPE- 385
Query: 154 PNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSKDEDFLDLS 203
N+D+ ++ W + ++F G L + C C S+ + F DLS
Sbjct: 386 ---NLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 442
Query: 204 VDVEQN----TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHL 259
+ + + ++ C+R F+ + L + K C CR ++ K+ +++ P IL LHL
Sbjct: 443 LPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHL 502
Query: 260 KRFKYMDQLHRYTKLSYRVVFPL-ELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHY 318
KRF + R +KL+ V FPL +L L + + TN +Y+L AV H G+ GHY
Sbjct: 503 KRFS--ESRIRTSKLTTFVNFPLRDLDLREFASENTN-HAVYNLYAVSNHSGTTMG-GHY 558
Query: 319 IAIVKSHDF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQ 367
A +S W F+D V + + + TSD Y+LFY+
Sbjct: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVR-----TSD-------AYLLFYE 597
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 112 bits (280), Expect = 5e-25
Identities = 99/365 (27%), Positives = 154/365 (42%), Gaps = 54/365 (14%)
Query: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPR-----KKESLLTCLADLFHSIA 92
+ GL N GNTC+ N+VLQ L RP R+ L + + + L AD+ ++
Sbjct: 211 HVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGAL- 269
Query: 93 TQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR 152
+ P +F +K F Y QQDA EFL L+ + L+ R+ +
Sbjct: 270 WHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLH--LEINRRGRRAPPI 327
Query: 153 LPNGNIDNE-------------NNNSTPDPTW----------VDEIFQGTLTNETRCLTC 189
L NG + + +++ + W + ++F G L + +C C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 190 ETISSKDEDFLDLSVDVEQN------TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAH 243
S+ E F DLS+ + + S+ C F+ E L SE C+ CR K +
Sbjct: 388 GYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRST 447
Query: 244 KRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDL 302
K++ V++ P IL LHL RF K S V FPL+ L L + + D +Y L
Sbjct: 448 KKLTVQRFPRILVLHLNRFS--ASRGSIKKSSVGVDFPLQRLSLGDFASDKAG-SPVYQL 504
Query: 303 VAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGY 362
A+ H GS + GHY A+ + W +++D V + + S GY
Sbjct: 505 YALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSENQVA------------SSEGY 551
Query: 363 ILFYQ 367
+LFYQ
Sbjct: 552 VLFYQ 556
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 112 bits (280), Expect = 5e-25
Identities = 99/365 (27%), Positives = 154/365 (42%), Gaps = 54/365 (14%)
Query: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPR-----KKESLLTCLADLFHSIA 92
+ GL N GNTC+ N+VLQ L RP R+ L + + + L AD+ ++
Sbjct: 211 HVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGAL- 269
Query: 93 TQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGR 152
+ P +F +K F Y QQDA EFL L+ + L+ R+ +
Sbjct: 270 WHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLH--LEINRRGRRAPPI 327
Query: 153 LPNGNIDNE-------------NNNSTPDPTW----------VDEIFQGTLTNETRCLTC 189
L NG + + +++ + W + ++F G L + +C C
Sbjct: 328 LANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQAC 387
Query: 190 ETISSKDEDFLDLSVDVEQN------TSITHCLRGFSNTETLCSEYKYYCEECRSKQEAH 243
S+ E F DLS+ + + S+ C F+ E L SE C+ CR K +
Sbjct: 388 GYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRST 447
Query: 244 KRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDL 302
K++ V++ P IL LHL RF K S V FPL+ L L + + D +Y L
Sbjct: 448 KKLTVQRFPRILVLHLNRFS--ASRGSIKKSSVGVDFPLQRLSLGDFASDKAG-SPVYQL 504
Query: 303 VAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGY 362
A+ H GS + GHY A+ + W +++D V + + S GY
Sbjct: 505 YALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSENQVA------------SSEGY 551
Query: 363 ILFYQ 367
+LFYQ
Sbjct: 552 VLFYQ 556
>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
Length = 1102
Score = 110 bits (276), Expect = 2e-24
Identities = 98/337 (29%), Positives = 152/337 (45%), Gaps = 39/337 (11%)
Query: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQ-PRKKESLLTCLADLFHSIATQKK 96
Y GL N G TCY NS+LQ L+F R+ V ++ +S+ L +F+ + K
Sbjct: 213 YVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDK 272
Query: 97 KVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG 156
VG KK E D++MQ D E LL+
Sbjct: 273 PVGT---KKLTKSFGWET--LDSFMQHDVQELCRVLLD---------------------- 305
Query: 157 NIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCL 216
N++N+ + + T + ++F+G + + +C + S + ED+ D+ + ++ +I
Sbjct: 306 NVENKMKGTCVEGT-IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESF 364
Query: 217 RGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSY 276
+ E L + KY E QEA K +K LP +L L L RF Y Q + K++
Sbjct: 365 VDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKIND 423
Query: 277 RVVFPLELRL--FNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIV--KSHDFWLLFD 332
R FP +L L F D +P Y L AV+VH G + GHY+ + K W FD
Sbjct: 424 RFEFPEQLPLDEFLQKTDPKDPAN-YILHAVLVHSGDN-HGGHYVVYLNPKGDGKWCKFD 481
Query: 333 DDIVEK-IDAQAIEEFY-GLTSDIS-KNSESGYILFY 366
DD+V + +AIE Y G D+S ++ + Y+L Y
Sbjct: 482 DDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 518
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 109 bits (273), Expect = 3e-24
Identities = 91/337 (27%), Positives = 145/337 (43%), Gaps = 42/337 (12%)
Query: 38 YFGLVNFGNTCYCNSVLQ----------ALYFC-RPFREKVLAYKSQPRKKESLLTCLAD 86
+ GL N G TCY N+ LQ ALY C + +L Q K T
Sbjct: 88 FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEH 147
Query: 87 LFHSIAT-QKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
L + A Q I P F+ L D QQDA EF ++ + D L +++
Sbjct: 148 LQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTLSKQKN 202
Query: 146 QEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVD 205
+ +N V + F G T C C S F +L ++
Sbjct: 203 PDVRN--------------------IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELN 242
Query: 206 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYM 265
++ + +T C+ F E L + +Y+CE C+SKQ A +++++ LP L L L RF +
Sbjct: 243 IQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFD 302
Query: 266 DQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSH 325
Q KL+ + F E+ + +Y+L AV++H G GHYIA VK
Sbjct: 303 RQTGHKKKLNTYIGFS-EILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDP 361
Query: 326 DF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 360
W F+D+ +EK++ + ++ G+ D+++ S+S
Sbjct: 362 QSGEWYKFNDEDIEKMEGKKLQ--LGIEEDLAEPSKS 396
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 109 bits (273), Expect = 3e-24
Identities = 91/337 (27%), Positives = 145/337 (43%), Gaps = 42/337 (12%)
Query: 38 YFGLVNFGNTCYCNSVLQ----------ALYFC-RPFREKVLAYKSQPRKKESLLTCLAD 86
+ GL N G TCY N+ LQ ALY C + +L Q K T
Sbjct: 88 FVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTICEH 147
Query: 87 LFHSIAT-QKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
L + A Q I P F+ L D QQDA EF ++ + D L +++
Sbjct: 148 LQYLFALLQNSNRRYIDPSGFVKALG-----LDTGQQQDAQEFSKLFMSLLEDTLSKQKN 202
Query: 146 QEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVD 205
+ +N V + F G T C C S F +L ++
Sbjct: 203 PDVRN--------------------IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELN 242
Query: 206 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYM 265
++ + +T C+ F E L + +Y+CE C+SKQ A +++++ LP L L L RF +
Sbjct: 243 IQGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFD 302
Query: 266 DQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSH 325
Q KL+ + F E+ + +Y+L AV++H G GHYIA VK
Sbjct: 303 RQTGHKKKLNTYIGFS-EILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDP 361
Query: 326 DF--WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 360
W F+D+ +EK++ + ++ G+ D+++ S+S
Sbjct: 362 QSGEWYKFNDEDIEKMEGKKLQ--LGIEEDLAEPSKS 396
>gi|113415482 PREDICTED: Ubiquitin carboxyl-terminal hydrolase
17-like protein 5 [Homo sapiens]
Length = 530
Score = 105 bits (261), Expect = 8e-23
Identities = 86/330 (26%), Positives = 137/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
+ E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLAKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
sapiens]
Length = 559
Score = 104 bits (260), Expect = 1e-22
Identities = 87/332 (26%), Positives = 140/332 (42%), Gaps = 39/332 (11%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K+
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIDKN 294
Query: 278 VVFP--LELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD- 333
V +P L+++L+ + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMKLY--MSQTNSGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDA 352
Query: 334 -----DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 353 EVTASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 104 bits (259), Expect = 1e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQADHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
sapiens]
Length = 530
Score = 104 bits (259), Expect = 1e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
sapiens]
Length = 530
Score = 104 bits (259), Expect = 1e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo
sapiens]
Length = 530
Score = 104 bits (259), Expect = 1e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 103 bits (258), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 103 bits (258), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 103 bits (258), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 103 bits (258), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 103 bits (258), Expect = 2e-22
Identities = 86/330 (26%), Positives = 136/330 (41%), Gaps = 35/330 (10%)
Query: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLA--YKSQPRKKESLLTCLADLFHSIATQKKK 97
GL N GNTCY N+ LQ L + P +L+ + + + + C H
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQA-HITRALHNP 139
Query: 98 VGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGN 157
VI P + + F Q+DAHEFL + ++ + KQ + +
Sbjct: 140 GHVIQPSQALAAG------FHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSK----- 188
Query: 158 IDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLR 217
D T + +IF G ++ +CL C IS + +LD+++D++ S+ L
Sbjct: 189 ----------DTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALE 238
Query: 218 GFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYR 277
E L E Y+C C + A K + + +L L LKRF + K++
Sbjct: 239 QLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTG----NKIAKN 294
Query: 278 VVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD-FWLLFDD--- 333
V +P L + +Y L AV+VH G + GHY + VK+ + W DD
Sbjct: 295 VQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEV 354
Query: 334 ---DIVEKIDAQAIEEFYGLTSDISKNSES 360
I + QA FY S+ ++SES
Sbjct: 355 TASSITSVLSQQAYVLFYIQKSEWERHSES 384
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,184,216
Number of Sequences: 37866
Number of extensions: 627885
Number of successful extensions: 1937
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1532
Number of HSP's gapped (non-prelim): 200
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.