Guide to the Human Genome
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Name: APAF1 Sequence: fasta or formatted (338aa) NCBI GI: 32483363
Description:

apoptotic peptidase activating factor 1 isoform e

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
WD Repeat Proteins

Other entries for this name:
alt prot [1248aa] apoptotic peptidase activating factor 1 isoform c
alt prot [1205aa] apoptotic peptidase activating factor 1 isoform d
alt prot [1194aa] apoptotic peptidase activating factor 1 isoform b
alt prot [1237aa] apoptotic peptidase activating factor 1 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         17           2
 C cysteine            2.4          8           1
 D aspartate           6.5         22           2
 E glutamate           5.9         20           3
 F phenylalanine       2.1          7           1
 G glycine             6.2         21           2
 H histidine           3.3         11           1
 I isoleucine          5.3         18           2
 K lysine              8.9         30           2
 L leucine            12.4         42           2
 M methionine          3.0         10           1
 N asparagine          2.7          9           1
 P proline             3.3         11           1
 Q glutamine           4.4         15           3
 R arginine            4.7         16           1
 S serine              8.6         29           4
 T threonine           3.6         12           2
 V valine              8.3         28           2
 W tryptophan          1.8          6           1
 Y tyrosine            1.8          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   apoptotic peptidase activating factor 1 isoform e [H... 
APAF1                 0.933   apoptotic peptidase activating factor 1 isoform d [H...
APAF1                 0.933   apoptotic peptidase activating factor 1 isoform c [H...
APAF1                 0.888   apoptotic peptidase activating factor 1 isoform b [Ho...
APAF1                 0.888   apoptotic peptidase activating factor 1 isoform a [Ho...
JAKMIP2               0.009   Janus kinase and microtubule interacting protein 2 [...
SLFN5                 0.008   schlafen family member 5 
NVL                   0.006   nuclear VCP-like isoform 2 
NVL                   0.006   nuclear VCP-like isoform 1 
ABCC9                 0.006   ATP-binding cassette, sub-family C, member 9 isofor...
ABCC9                 0.006   ATP-binding cassette, sub-family C, member 9 isofor...
ABCC9                 0.006   ATP-binding cassette, sub-family C, member 9 isofor...
C6orf182              0.006   hypothetical protein LOC285753 
C6orf182              0.006   hypothetical protein LOC285753 
CARD8                 0.005   caspase recruitment domain family, member 8 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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