Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 32261332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32261332 seizure related 6 homolog (mouse)-like precursor
[Homo sapiens]
(1024 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 2106 0.0
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 864 0.0
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 847 0.0
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 792 0.0
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 792 0.0
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 790 0.0
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 679 0.0
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 260 4e-69
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 258 2e-68
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 233 5e-61
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 233 5e-61
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 233 5e-61
gi|148886654 polydom [Homo sapiens] 107 7e-23
gi|6912724 tolloid-like 2 [Homo sapiens] 105 2e-22
gi|22547221 tolloid-like 1 [Homo sapiens] 102 1e-21
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 100 5e-21
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 99 3e-20
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 97 1e-19
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 97 1e-19
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 96 1e-19
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 92 3e-18
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 91 4e-18
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 91 4e-18
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 89 2e-17
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 86 2e-16
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 86 2e-16
gi|168693643 decay accelerating factor for complement isoform 2 ... 86 2e-16
gi|10835143 decay accelerating factor for complement isoform 1 p... 86 2e-16
gi|62912468 complement component 4 binding protein, beta chain i... 84 7e-16
gi|62912464 complement component 4 binding protein, beta chain i... 84 7e-16
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 2106 bits (5456), Expect = 0.0
Identities = 1024/1024 (100%), Positives = 1024/1024 (100%)
Query: 1 MPAARPPAAGLRGISLFLALLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKE 60
MPAARPPAAGLRGISLFLALLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKE
Sbjct: 1 MPAARPPAAGLRGISLFLALLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKE 60
Query: 61 HPEERVVTAPPSSSQSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLP 120
HPEERVVTAPPSSSQSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLP
Sbjct: 61 HPEERVVTAPPSSSQSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLP 120
Query: 121 SLKQVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEAS 180
SLKQVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEAS
Sbjct: 121 SLKQVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEAS 180
Query: 181 EVPLWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPM 240
EVPLWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPM
Sbjct: 181 EVPLWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPM 240
Query: 241 ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL 300
ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL
Sbjct: 241 ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL 300
Query: 301 PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI 360
PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI
Sbjct: 301 PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI 360
Query: 361 RSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCH 420
RSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCH
Sbjct: 361 RSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCH 420
Query: 421 LGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCI 480
LGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCI
Sbjct: 421 LGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCI 480
Query: 481 WTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTI 540
WTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTI
Sbjct: 481 WTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTI 540
Query: 541 RIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSL 600
RIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSL
Sbjct: 541 RIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSL 600
Query: 601 EQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV 660
EQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV
Sbjct: 601 EQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV 660
Query: 661 GEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
GEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD
Sbjct: 661 GEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Query: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV
Sbjct: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
Query: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL
Sbjct: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM
Sbjct: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
Query: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALA 960
CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALA
Sbjct: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALA 960
Query: 961 IFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREY 1020
IFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREY
Sbjct: 961 IFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREY 1020
Query: 1021 EVSI 1024
EVSI
Sbjct: 1021 EVSI 1024
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 864 bits (2232), Expect = 0.0
Identities = 453/1030 (43%), Positives = 631/1030 (61%), Gaps = 53/1030 (5%)
Query: 11 LRGISLFLA---LLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKEHPEERV- 66
+R ++L L L L + +LE + +G A P + + +P E PE V
Sbjct: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQA----PGIEETDGELTAAPTPEQPERGVH 56
Query: 67 -VTAPPSSS--QSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLPSLK 123
VT P+ +L E + +G PAL P P+ P P LP L
Sbjct: 57 FVTTAPTLKLLNHHPLLEEFLQEGLEKGDEELRPAL-PFQPDPPAPFTPSP----LPRL- 110
Query: 124 QVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEASEVP 183
A + RP TS PA + S E P P P++
Sbjct: 111 ----ANQDSRPVFTSPT--------PAMAAVPTQPQSKEGPWSPESESPML--------- 149
Query: 184 LWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPE--PGEPGP-DMAQEAPQEDTSPM 240
P P P P +A T P P + GP DM + E S
Sbjct: 150 ------RITAPLPPGPSMAVPTLGPGEIASTTPPSRAWTPTQEGPGDMGRPWVAEVVSQG 203
Query: 241 ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL 300
A + + +AS + +ETTT+T I TT ITT Q P CS +FS PEG +DS
Sbjct: 204 AGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSS 263
Query: 301 PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI 360
P + L+C + ++VY GYGVE++V++++L +GE +++ G+ GP LANQ+ L+ GQVI
Sbjct: 264 PTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVI 323
Query: 361 RSPTNTISVYFRTFQDD-GLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHC 419
RSPT+ ++ F++ G GTF HYQA++LSC+FPRRP GDVTV LH GG A FHC
Sbjct: 324 RSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHC 383
Query: 420 HLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
GY+L+GA+ LTC+NA++P W S+EP+C A CGG + NAT GR++SP +P N + + C
Sbjct: 384 ATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTC 443
Query: 480 IWTIEAPEGQKLHLHFERL-LLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
W +EAPEGQ+LHLHFE++ L D DR+ + +G ++ +YDS + E +P EGLLS G
Sbjct: 444 HWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGK 503
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGH 598
+E ++D + AA+ +R+EAF++GHCYEP+++ GNF++S PTY +GT VEF+CDPG+
Sbjct: 504 HFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGY 563
Query: 599 SLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKI 658
+LEQG IIEC++ DP WN+TEP CRA+C GE++ AGVVLSPNWPEPY G+DCIW +
Sbjct: 564 TLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGV 623
Query: 659 HVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFH 718
HV E+KRI LDI+ L + D+LT YDGD++ +LGQY G KL++S D+TIQF
Sbjct: 624 HVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQ 683
Query: 719 SDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYD 778
SDP + G QGF++++ EV RND+C +LPEI NGWK+ S ELV G +TYQC PGY
Sbjct: 684 SDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQ 743
Query: 779 IVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGF 838
+VGS L CQWDL+WS D P C+++ C DPG+V+HS RLIS P VG T+QY C+ GF
Sbjct: 744 VVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGF 803
Query: 839 VLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLT 898
VL GSS+LTC+ R+ G+P W+ R P C+ E+ C PENG + K+L+ G ++
Sbjct: 804 VLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH 863
Query: 899 FMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK-VNQDSF--EHALEVAEA-AAETSLEG 954
F C G+ L G+ +I+C+ G PSHW+ P P+C+ + D F +L+VA+A AA ++L+
Sbjct: 864 FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDA 923
Query: 955 GNMALAIFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYET 1014
++A AIF+P++ + LL+GG Y Y +R + S+L+LP PY++IT+E+ FDNP YET
Sbjct: 924 AHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYET 983
Query: 1015 GETREYEVSI 1024
GETREYEVSI
Sbjct: 984 GETREYEVSI 993
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 847 bits (2188), Expect = 0.0
Identities = 444/1021 (43%), Positives = 622/1021 (60%), Gaps = 53/1021 (5%)
Query: 11 LRGISLFLA---LLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKEHPEERV- 66
+R ++L L L L + +LE + +G A P + + +P E PE V
Sbjct: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQA----PGIEETDGELTAAPTPEQPERGVH 56
Query: 67 -VTAPPSSS--QSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLPSLK 123
VT P+ +L E + +G PAL P P+ P P LP L
Sbjct: 57 FVTTAPTLKLLNHHPLLEEFLQEGLEKGDEELRPAL-PFQPDPPAPFTPSP----LPRL- 110
Query: 124 QVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEASEVP 183
A + RP TS PA + S E P P P++
Sbjct: 111 ----ANQDSRPVFTSPT--------PAMAAVPTQPQSKEGPWSPESESPML--------- 149
Query: 184 LWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPE--PGEPGP-DMAQEAPQEDTSPM 240
P P P P +A T P P + GP DM + E S
Sbjct: 150 ------RITAPLPPGPSMAVPTLGPGEIASTTPPSRAWTPTQEGPGDMGRPWVAEVVSQG 203
Query: 241 ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL 300
A + + +AS + +ETTT+T I TT ITT Q P CS +FS PEG +DS
Sbjct: 204 AGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSS 263
Query: 301 PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI 360
P + L+C + ++VY GYGVE++V++++L +GE +++ G+ GP LANQ+ L+ GQVI
Sbjct: 264 PTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVI 323
Query: 361 RSPTNTISVYFRTFQDD-GLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHC 419
RSPT+ ++ F++ G GTF HYQA++LSC+FPRRP GDVTV LH GG A FHC
Sbjct: 324 RSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHC 383
Query: 420 HLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
GY+L+GA+ LTC+NA++P W S+EP+C A CGG + NAT GR++SP +P N + + C
Sbjct: 384 ATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTC 443
Query: 480 IWTIEAPEGQKLHLHFERL-LLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
W +EAPEGQ+LHLHFE++ L D DR+ + +G ++ +YDS + E +P EGLLS G
Sbjct: 444 HWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGK 503
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGH 598
+E ++D + AA+ +R+EAF++GHCYEP+++ GNF++S PTY +GT VEF+CDPG+
Sbjct: 504 HFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGY 563
Query: 599 SLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKI 658
+LEQG IIEC++ DP WN+TEP CRA+C GE++ AGVVLSPNWPEPY G+DCIW +
Sbjct: 564 TLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGV 623
Query: 659 HVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFH 718
HV E+KRI LDI+ L + D+LT YDGD++ +LGQY G KL++S D+TIQF
Sbjct: 624 HVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQ 683
Query: 719 SDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYD 778
SDP + G QGF++++ EV RND+C +LPEI NGWK+ S ELV G +TYQC PGY
Sbjct: 684 SDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQ 743
Query: 779 IVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGF 838
+VGS L CQWDL+WS D P C+++ C DPG+V+HS RLIS P VG T+QY C+ GF
Sbjct: 744 VVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGF 803
Query: 839 VLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLT 898
VL GSS+LTC+ R+ G+P W+ R P C+ E+ C PENG + K+L+ G ++
Sbjct: 804 VLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH 863
Query: 899 FMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK-VNQDSF--EHALEVAEA-AAETSLEG 954
F C G+ L G+ +I+C+ G PSHW+ P P+C+ + D F +L+VA+A AA ++L+
Sbjct: 864 FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDA 923
Query: 955 GNMALAIFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYET 1014
++A AIF+P++ + LL+GG Y Y +R + S+L+LP PY++IT+E+ FDNP YET
Sbjct: 924 AHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYET 983
Query: 1015 G 1015
G
Sbjct: 984 G 984
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 [Homo
sapiens]
Length = 910
Score = 792 bits (2046), Expect = 0.0
Identities = 398/841 (47%), Positives = 537/841 (63%), Gaps = 53/841 (6%)
Query: 192 AVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPMALMDKGENELT 251
A PT P L P T T P P P PGP + E +E
Sbjct: 115 AGPTAPELLTPPPGT-------TAPPPPSPASPGPPLGPEGGEE---------------- 151
Query: 252 GSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDY--PLLPLNNFLECT 309
ETTT+ I TTTV TT +P LC+ + S EGY++S D P+ L+CT
Sbjct: 152 --------ETTTTIITTTTVTTTVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCT 203
Query: 310 YNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTNT 366
Y++ VY GYG+E+QV+++NLS + ELL + G P L +LAN ++L EGQV+RSPTN
Sbjct: 204 YSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNR 263
Query: 367 ISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQ 426
+ ++F++ + G F++HYQA++LSC FP RP GDV+V DLH GG A FHC GY+LQ
Sbjct: 264 LLLHFQSPRVPRGGGFRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQ 323
Query: 427 GAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAP 486
G + L C+N ++P W+ + P C A CGG +HNAT+GR++SP + C W IEA
Sbjct: 324 GEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAA 383
Query: 487 EGQKLHLHFERLLL-HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFT 545
EG++LHLHFER+ L D DR+ V SG + S ++YDS + VP GL+S+ ++ +E
Sbjct: 384 EGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELL 442
Query: 546 SDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQG-- 603
S+ ++RFEAFE+ C+ P++ +GN TT+DP Y G + F+C PG++LE
Sbjct: 443 SETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGP 502
Query: 604 PAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
P IEC++ +P+WNDTEP C+AMCGGELS AGVVLSP+WP+ Y G+DC+W +HV EE
Sbjct: 503 PNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEE 562
Query: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAG 723
KRI L ++ LN+ D+LT++DGD +L Q G ++L SS PDLT+QF + P
Sbjct: 563 KRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGP 622
Query: 724 LIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSD 783
G GQGF++++ EV RND+C +LP + GW+T SH +L+RG +TYQC+PGY+++GSD
Sbjct: 623 PNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSD 682
Query: 784 TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGS 843
LTCQWDLSWS+ PP C+KIM C DPGE+ + R SD VG+ +QY C PG+ LEG+
Sbjct: 683 ILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGA 742
Query: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYE 903
++LTCYSR+TGTP W+ R+P C + C NPG+PENGYQ LYK Y GESL F CYE
Sbjct: 743 AMLTCYSRDTGTPKWSDRVPKCALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYE 801
Query: 904 GFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALAIFI 963
GFEL+GEVTI C+ G PS W P+CKV Q + LEGGN+ALAI +
Sbjct: 802 GFELIGEVTITCVPGHPSQWTSQPPLCKVTQTT----------DPSRQLEGGNLALAILL 851
Query: 964 PVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVS 1023
P+ ++ +L G YIY T+ + S SH YS ITVE++F NP+YE G+TREYEVS
Sbjct: 852 PLGLVIVLGSGVYIYYTKLQGKS--LFGFSGSHSYSPITVESDFSNPLYEAGDTREYEVS 909
Query: 1024 I 1024
I
Sbjct: 910 I 910
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 792 bits (2045), Expect = 0.0
Identities = 399/822 (48%), Positives = 542/822 (65%), Gaps = 21/822 (2%)
Query: 219 PEPGEPGPDMAQEAPQEDTSPMALMDKGENE--LTGS--ASEESQETTTSTIITTTVITT 274
PEPG P +A EA E AL+ +G L G E +E TT+TIITTT +TT
Sbjct: 37 PEPGSETPTVASEALAELLHG-ALLRRGPEMGYLPGPPLGPEGGEEETTTTIITTTTVTT 95
Query: 275 E-QAPALCSVSFSNPEGYIDSSDY--PLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS- 330
+P LC+ + S EGY++S D P+ L+CTY++ VY GYG+E+QV+++NLS
Sbjct: 96 TVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQ 155
Query: 331 DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA 388
+ ELL + G P L +LAN ++L EGQV+RSPTN + ++F++ + G F++HYQA
Sbjct: 156 EEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 389 FMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
++LSC FP RP GDV+V DLH GG A FHC GY+LQG + L C+N ++P W+ + P C
Sbjct: 216 YLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL-HDKDRMT 507
A CGG +HNAT+GR++SP + C W IEA EG++LHLHFER+ L D DR+
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 508 VHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
V SG + S ++YDS + VP GL+S+ ++ +E S+ ++RFEAFE+ C
Sbjct: 336 VRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC 394
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQG--PAIIECINVRDPYWNDTEPLCR 625
+ P++ +GN TT+DP Y G + F+C PG++LE P IEC++ +P+WNDTEP C+
Sbjct: 395 FAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYD 685
AMCGGELS AGVVLSP+WP+ Y G+DC+W +HV EEKRI L ++ LN+ D+LT++D
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFD 514
Query: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
GD +L Q G ++L SS PDLT+QF + P G GQGF++++ EV RND+C
Sbjct: 515 GDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC 574
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
+LP + GW+T SH +L+RG +TYQC+PGY+++GSD LTCQWDLSWS+ PP C+KIM
Sbjct: 575 PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMT 634
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPGE+ + R SD VG+ +QY C PG+ LEG+++LTCYSR+TGTP W+ R+P C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNG 925
+ C NPG+PENGYQ LYK Y GESL F CYEGFEL+GEVTI C+ G PS W
Sbjct: 695 ALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTS 753
Query: 926 PLPVCKVNQDSF--EHALEVAEAA-AETSLEGGNMALAIFIPVLIISLLLGGAYIYITRC 982
P+CKV + LEV + LEGGN+ALAI +P+ ++ +L G YIY T+
Sbjct: 754 QPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKL 813
Query: 983 RYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI 1024
+ S SH YS ITVE++F NP+YE G+TREYEVSI
Sbjct: 814 QGKS--LFGFSGSHSYSPITVESDFSNPLYEAGDTREYEVSI 853
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 [Homo
sapiens]
Length = 840
Score = 790 bits (2039), Expect = 0.0
Identities = 397/819 (48%), Positives = 539/819 (65%), Gaps = 28/819 (3%)
Query: 219 PEPGEPGPDMAQEAPQEDTSPMALMDKGENE--LTGS--ASEESQETTTSTIITTTVITT 274
PEPG P +A EA E AL+ +G L G E +E TT+TIITTT +TT
Sbjct: 37 PEPGSETPTVASEALAELLHG-ALLRRGPEMGYLPGPPLGPEGGEEETTTTIITTTTVTT 95
Query: 275 E-QAPALCSVSFSNPEGYIDSSDY--PLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS- 330
+P LC+ + S EGY++S D P+ L+CTY++ VY GYG+E+QV+++NLS
Sbjct: 96 TVTSPVLCNNNISEGEGYVESPDLGSPVSRTLGLLDCTYSIHVYPGYGIEIQVQTLNLSQ 155
Query: 331 DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA 388
+ ELL + G P L +LAN ++L EGQV+RSPTN + ++F++ + G F++HYQA
Sbjct: 156 EEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFRIHYQA 215
Query: 389 FMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
++LSC FP RP GDV+V DLH GG A FHC GY+LQG + L C+N ++P W+ + P C
Sbjct: 216 YLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL-HDKDRMT 507
A CGG +HNAT+GR++SP + C W IEA EG++LHLHFER+ L D DR+
Sbjct: 276 MASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLM 335
Query: 508 VHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
V SG + S ++YDS + VP GL+S+ ++ +E S+ ++RFEAFE+ C
Sbjct: 336 VRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRC 394
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQG--PAIIECINVRDPYWNDTEPLCR 625
+ P++ +GN TT+DP Y G + F+C PG++LE P IEC++ +P+WNDTEP C+
Sbjct: 395 FAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACK 454
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYD 685
AMCGGELS AGVVLSP+WP+ Y G+DC+W +HV EEKRI L ++ LN+ D+LT++D
Sbjct: 455 AMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFD 514
Query: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
GD +L Q G ++L SS PDLT+QF + P G GQGF++++ EV RND+C
Sbjct: 515 GDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTC 574
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
+LP + GW+T SH +L+RG +TYQC+PGY+++GSD LTCQWDLSWS+ PP C+KIM
Sbjct: 575 PELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMT 634
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPGE+ + R SD VG+ +QY C PG+ LEG+++LTCYSR+TGTP W+ R+P C
Sbjct: 635 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKC 694
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNG 925
+ C NPG+PENGYQ LYK Y GESL F CYEGFEL+GEVTI C+ G PS W
Sbjct: 695 ALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTS 753
Query: 926 PLPVCKVNQDSFEHALEVAEAAAETSLEGGNMALAIFIPVLIISLLLGGAYIYITRCRYY 985
P+CKV Q + LEGGN+ALAI +P+ ++ +L G YIY T+ +
Sbjct: 754 QPPLCKVTQTT----------DPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTKLQGK 803
Query: 986 SNLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI 1024
S SH YS ITVE++F NP+YE G+TREYEVSI
Sbjct: 804 S--LFGFSGSHSYSPITVESDFSNPLYEAGDTREYEVSI 840
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 [Homo
sapiens]
Length = 809
Score = 679 bits (1751), Expect = 0.0
Identities = 323/643 (50%), Positives = 432/643 (67%), Gaps = 10/643 (1%)
Query: 388 AFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPI 447
A++LSC FP RP GDV+V DLH GG A FHC GY+LQG + L C+N ++P W+ + P
Sbjct: 171 AYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPS 230
Query: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL-HDKDRM 506
C A CGG +HNAT+GR++SP + C W IEA EG++LHLHFER+ L D DR+
Sbjct: 231 CMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V SG + S ++YDS + VP GL+S+ ++ +E S+ ++RFEAFE+
Sbjct: 291 MVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQG--PAIIECINVRDPYWNDTEPLC 624
C+ P++ +GN TT+DP Y G + F+C PG++LE P IEC++ +P+WNDTEP C
Sbjct: 350 CFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPAC 409
Query: 625 RAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIY 684
+AMCGGELS AGVVLSP+WP+ Y G+DC+W +HV EEKRI L ++ LN+ D+LT++
Sbjct: 410 KAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLF 469
Query: 685 DGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDS 744
DGD +L Q G ++L SS PDLT+QF + P G GQGF++++ EV RND+
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
C +LP + GW+T SH +L+RG +TYQC+PGY+++GSD LTCQWDLSWS+ PP C+KIM
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 589
Query: 805 YCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPH 864
C DPGE+ + R SD VG+ +QY C PG+ LEG+++LTCYSR+TGTP W+ R+P
Sbjct: 590 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 649
Query: 865 CVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWN 924
C + C NPG+PENGYQ LYK Y GESL F CYEGFEL+GEVTI C+ G PS W
Sbjct: 650 CALKYE-PCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 925 GPLPVCKVNQDSF--EHALEVAEAA-AETSLEGGNMALAIFIPVLIISLLLGGAYIYITR 981
P+CKV + LEV + LEGGN+ALAI +P+ ++ +L G YIY T+
Sbjct: 709 SQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYTK 768
Query: 982 CRYYSNLRLPLMYSHPYSQITVETEFDNPIYETGETREYEVSI 1024
+ S SH YS ITVE++F NP+YE G+TREYEVSI
Sbjct: 769 LQGKS--LFGFSGSHSYSPITVESDFSNPLYEAGDTREYEVSI 809
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/184 (28%), Positives = 84/184 (45%), Gaps = 11/184 (5%)
Query: 273 TTEQAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG 332
T A+C S P G + S D+P + +C + V V + LQV+ +N+ +G
Sbjct: 405 TEPACKAMCGGELSEPAGVVLSPDWPQ-SYSPGQDCVWGVHVQEEKRILLQVEILNVREG 463
Query: 333 ELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRT---FQDDGLGT-FQLHYQA 388
++L++ DGP+ VLA + + S +++ F+ + GLG F LH++
Sbjct: 464 DMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKE 523
Query: 389 FMLSCNFPR--RPDSGDVTVM--DLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQ 444
+ P P+ G T DL G V + C GYEL G+ +LTC WS+
Sbjct: 524 VPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTC--QWDLSWSAA 581
Query: 445 EPIC 448
P C
Sbjct: 582 PPAC 585
Score = 37.4 bits (85), Expect = 0.073
Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 32/111 (28%)
Query: 192 AVPTTPAPLQISPFTSQPYVAHTLPQRPEPGEPGPDMAQEAPQEDTSPMALMDKGENELT 251
A PT P L P T T P P P PGP + E +E
Sbjct: 115 AGPTAPELLTPPPGT-------TAPPPPSPASPGPPLGPEGGEE---------------- 151
Query: 252 GSASEESQETTTSTIITTTVITTEQAPA-LCSVSFSNPEGYIDSSDYPLLP 301
ETTT+ I TTTV TT +PA L S F + D S L P
Sbjct: 152 --------ETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHP 194
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 260 bits (665), Expect = 4e-69
Identities = 207/717 (28%), Positives = 330/717 (46%), Gaps = 81/717 (11%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C S + +G + S ++P+ NN EC Y++ G G++L+ ++ LS+G++L +
Sbjct: 1096 AECGNSVTGTQGTLLSPNFPV-NYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVY 1154
Query: 339 GVDGPT---LTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCN 394
+ + L V ++ ++ G + S ++++ + F T ++ F+LH+ +F ++ C
Sbjct: 1155 DGNNNSARLLGVFSHSEMM--GVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
Query: 395 FPRRPDSGDVTVMDLH-SGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
P P G + H +G F C GY L+G++ L C++ + W P C A CG
Sbjct: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECG 1272
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD----KDRMTVH 509
G V G+VLSP YP + CIWTIEA G + LHF L+ D D + +
Sbjct: 1273 GTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHF---LVFDTEEVHDVLRIW 1329
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
G +S +L L ++P + L S N++ ++F++D + F I+F C +
Sbjct: 1330 DGPV-ESGVLLKELSGPALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCND 1387
Query: 570 PYI-QNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDP-YWNDTEPLCRAM 627
P I QNG + S ++ G F CDPG++L QG A I C+ + + +W + P C A
Sbjct: 1388 PGIPQNG--SRSGDSWEAGDSTVFQCDPGYAL-QGSAEISCVKIENRFFWQPSPPTCIAP 1444
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS-NSDILTIYDG 686
CGG+L+ +GV+LSPN+PEPY G++C WK+ V + I L NL D L IYDG
Sbjct: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDG 1504
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
+ + ++G + G+ P ++ SS+ L + F SD + GF+++Y E R +SC
Sbjct: 1505 RDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDAS----VSNAGFVIDYTENPR-ESCF 1559
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEK 802
D I+NG + S +L G+ +TY C GY++ G+ TL+C W++ P C
Sbjct: 1560 DPGSIKNGTRVGSDLKL--GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 1617
Query: 803 I---MYCTDPGEV---DHSTRLISDPVLLVGTTI--QYTCNPGFVLEGSSLLTCYSRETG 854
Y G V ++ S + L T+ Y F ++L G
Sbjct: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDG 1677
Query: 855 TPIWTSRL-----PHCVSEESLACDNPGL---------PENGYQILY------------- 887
+ L H LA N L P G+ +Y
Sbjct: 1678 HSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSS 1737
Query: 888 -------KRL---YLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
KRL + G + F C G+ L G I C + G + WN P C V
Sbjct: 1738 VPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV 1794
Score = 210 bits (534), Expect = 6e-54
Identities = 166/539 (30%), Positives = 255/539 (47%), Gaps = 34/539 (6%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
A C + P G I S +YP P EC + VTV Y + L NL G + L I
Sbjct: 1443 APCGGDLTGPSGVILSPNYPE-PYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
Query: 338 R-GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHY-QAFMLSCNF 395
G D + + + + G+ I S +N++ + FR+ F + Y + SC
Sbjct: 1502 YDGRDSLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
Query: 396 PRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINA--SKPHWSSQEPICSAPCG 453
P +G DL G ++CH GYE++G L+CI KP W++ P+C+APCG
Sbjct: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCG 1620
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQT 513
G + + G VLSP+YP+N Q C++ + P+ + F D + VH G +
Sbjct: 1621 GQ-YVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHS 1679
Query: 514 NKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE- 569
S LL S ES+P L+ N + I+F++ A F+ ++A + +
Sbjct: 1680 QHSRLLSSLSGSHTGESLP----LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQC 1735
Query: 570 ---PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLC 624
P + G SD +++G IV F C+ G++L+ P I EC+ V WN + P C
Sbjct: 1736 SSVPEPRYGKRLGSD--FSVGAIVRFECNSGYALQGSPEI-ECLPVPGALAQWNVSAPTC 1792
Query: 625 RAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTI 683
CGG L+ G +LSP +PEPY+ +C+WKI V E I + + F+ N D L +
Sbjct: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
Query: 684 YDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRND 743
+DG + +LG + G + P L S++ L + F+SD I GF + Y V +
Sbjct: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSD----ISVSAAGFHLEYKTVGLS- 1907
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL--SWSSDPPFC 800
SC + NG K T LV +++QC+PGY + G ++C W+ PP C
Sbjct: 1908 SCPEPAVPSNGVK-TGERYLVNDV-VSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
Score = 188 bits (477), Expect = 3e-47
Identities = 166/609 (27%), Positives = 259/609 (42%), Gaps = 69/609 (11%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C + +G + S +YP + + C Y VTV Y V Q + + +++ +
Sbjct: 1617 APCGGQYVGSDGVVLSPNYPQNYTSGQI-CLYFVTVPKDYVVFGQFAFFHTALNDVVEVH 1675
Query: 339 GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGT---FQLHYQAF----ML 391
+L++ + G+ + P T + F GL F YQA
Sbjct: 1676 DGHSQHSRLLSSLSGSHTGESL--PLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSAT 1733
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC--INASKPHWSSQEPICS 449
C+ P G D G + F C+ GY LQG+ + C + + W+ P C
Sbjct: 1734 QCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV 1793
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
PCGG + G +LSP +PE S C+W I PEG + + + D + V
Sbjct: 1794 VPCGGNLTERR-GTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
Query: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
G N +L S +VP L S N + + F SD + +A+ F++ ++ C
Sbjct: 1853 FDGADNTVTML-GSFSGTTVPAL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC 628
EP + + T + Y + +V F C+PG++L QG A I C+ WN PLC A C
Sbjct: 1911 EPAVPSNGVKTGE-RYLVNDVVSFQCEPGYAL-QGHAHISCMPGTVRRWNYPPPLCIAQC 1968
Query: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS---NSDILTIYD 685
GG + + GV+LSP +P Y DC WKI + IQFLN S N D + I +
Sbjct: 1969 GGTVEEMEGVILSPGFPGNYPSNMDCSWKIAL--PVGFGAHIQFLNFSTEPNHDYIEIRN 2026
Query: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
G ++G++ G+ P L S++ + T+ FHSD + GF + Y +++ +
Sbjct: 2027 GPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHS----QNRPGFKLEYQDLTYSHQI 2082
Query: 746 S------DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPF 799
S DL E++ T+ T V + + WDL P
Sbjct: 2083 SSFLRGFDLSELER----TNSTPPVAASYV-------------------WDLD-----PG 2114
Query: 800 CE--KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGT-P 856
CE ++ C DP + ++ VG ++ + C PG+ L G +LTC + GT
Sbjct: 2115 CEAYELQECPDP--EPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTC---QHGTNR 2169
Query: 857 IWTSRLPHC 865
W LP C
Sbjct: 2170 NWDHPLPKC 2178
Score = 187 bits (476), Expect = 3e-47
Identities = 155/539 (28%), Positives = 236/539 (43%), Gaps = 34/539 (6%)
Query: 280 LCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGV-ELQVKSVNLSDG-ELLSI 337
+C P G I S ++P+ NN C + +T V +L + +L G + L++
Sbjct: 404 MCDAHLRGPSGIITSPNFPIQYDNN-AHCVWIITALNPSKVIKLAFEEFDLERGYDTLTV 462
Query: 338 R--GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGT---FQLHYQAFML- 391
G DG TVL T +I S + + + F+T DG G+ F+ Y+
Sbjct: 463 GDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQT---DGSGSSLGFKASYEEIEQG 519
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
SC P P G H G F C +EL G K +TC WS+++P C
Sbjct: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITC--QKNNQWSAKKPGCVFS 577
Query: 452 CGGAVHNAT--IGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
C N T G VLSP+YPE+ C+W I A ++HL F + + + D + +
Sbjct: 578 C---FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
Query: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
G T ++ +L + +P + S G+ R+EF +D + FNI F F C
Sbjct: 635 KDGATAEAPVL-GTFSGNQLP-SSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECP 692
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLCRAM 627
+P + D + +G+ + F CD G QG I C+ WN C A
Sbjct: 693 DPGVPVNGKRFGD-SLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAP 751
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV--GEEKRIFLDIQFLNLSNSDILTIYD 685
CGG L++ +G +LSP WP Y + C W I G +I D +F N D L + D
Sbjct: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFD-RFKTEVNYDTLEVRD 810
Query: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS-RNDS 744
G ++G Y G PQ L S++ L + F +D + GF + Y ++ ++D
Sbjct: 811 GRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKS----HSDIGFQLRYETITLQSDH 866
Query: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
C D NG + + GA +T+ CD GY + + L C+ + WS P CE +
Sbjct: 867 CLDPGIPVNGQR--HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL 923
Score = 185 bits (470), Expect = 2e-46
Identities = 189/774 (24%), Positives = 297/774 (38%), Gaps = 86/774 (11%)
Query: 219 PEPGEP-GPDMAQEAPQEDTSPMALMDKGENELTGSASEESQETTTSTIITTTVITTEQA 277
P+PG P ++ Q +S L D+G GS + S + + V+ E
Sbjct: 692 PDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCE-- 749
Query: 278 PALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVK----SVNLSDGE 333
A C ++P G I S +P + L C + + GY +++ VN E
Sbjct: 750 -APCGGHLTSPSGTILSPGWPGF-YKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLE 807
Query: 334 LLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS- 392
+ R P + V + Q + S +N + + F T + FQL Y+ L
Sbjct: 808 VRDGRTYSAPLIGVYHGTQV---PQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
Query: 393 --CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPIC 448
C P P +G D + G + F C GY L + L C +P+ WS P C
Sbjct: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLEC----EPNFQWSRALPSC 920
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL---HDKDR 505
A CGG + ++ G +LSP +P+ + C W IE G+ + F L HD
Sbjct: 921 EALCGGFIQGSS-GTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLL 979
Query: 506 MTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
+T + T L S P L T ++ F SD + + FNI F ++
Sbjct: 980 ITENGSFTQPLRQLTGSRLP--APISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE 1037
Query: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C EP + + + +G + F+C PG+ LE G A I C+ R W+ P C
Sbjct: 1038 PCEEPEVPAYSIRKG-LQFGVGDTLTFSCFPGYRLE-GTARITCLGGRRRLWSSPLPRCV 1095
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYD 685
A CG ++ G +LSPN+P Y +CI+ I K I L + LS D+L +YD
Sbjct: 1096 AECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYD 1155
Query: 686 GDEVMPHILGQYL-GNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDS 744
G+ +LG + L S++ L + F +D +GF +++
Sbjct: 1156 GNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAE----NTSKGFELHFSSFEL-IK 1210
Query: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEK 802
C D + G+K G+ +++ CDPGY + GS+ L C +W P C
Sbjct: 1211 CEDPGTPKFGYKVHDEGHFA-GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
Query: 803 IMYCTDPGEVD------------------------------------------HSTRLIS 820
T GEV H I
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIW 1329
Query: 821 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVS---EESLACDNPG 877
D + G ++ P + S + T +TS+ + + +C++PG
Sbjct: 1330 DGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPG 1389
Query: 878 LPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI-LGQPSHWNGPLPVC 930
+P+NG + + G+S F C G+ L G I C+ + W P C
Sbjct: 1390 IPQNGSR--SGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 170 bits (431), Expect = 6e-42
Identities = 173/710 (24%), Positives = 283/710 (39%), Gaps = 76/710 (10%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
A C + EG I S +P +N ++C++ + + G+G +Q + + + + I
Sbjct: 1966 AQCGGTVEEMEGVILSPGFPGNYPSN-MDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEI 2024
Query: 338 RGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS---CN 394
R T ++ + + S ++ +VYF + F+L YQ S +
Sbjct: 2025 RNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISS 2084
Query: 395 FPRRPDSGDVT------------VMDLHSGGVAH-------------------------- 416
F R D ++ V DL G A+
Sbjct: 2085 FLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQS 2144
Query: 417 --FHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTN 474
F C GY+L G +LTC + + +W P C PCGG + ++ G V SP +P +
Sbjct: 2145 VTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSN-GTVYSPGFPSPYS 2203
Query: 475 GSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDSLQTESVPFEGL 533
SQ C+W I P G + L+ L D +T+ G + L + T S+ + +
Sbjct: 2204 SSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRL--GVFTRSMAKKTV 2261
Query: 534 LSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEF 592
S N + ++F D A F I F A+ C P I N T + +NIG IV +
Sbjct: 2262 QSSSNQVLLKFHRD-AATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRY 2320
Query: 593 TCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE--LSAVAGVVLSPNWPEPYVE 650
C PG +L G I+ C + P+C C L+ GV+LS ++P Y +
Sbjct: 2321 RCLPGFTL-VGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQ 2379
Query: 651 GEDCIWKIHVGEEKRIFLDIQ-FLNLSNSDILTIYDGDEVMPHILGQYLGN-SGPQKLYS 708
+ C W + V + I L ++ FL+ D I+DG +L GN S P + S
Sbjct: 2380 FQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTS 2439
Query: 709 STPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGAR 768
S+ + +++ SD A +GF + Y CS LP T G
Sbjct: 2440 SSNSVYLRWSSDHA----YNRKGFKIRY----SAPYCS-LPRAPLHGFILGQTSTQPGGS 2490
Query: 769 ITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVL 824
I + C+ GY +VG C Q WS P C+ + C P + ++
Sbjct: 2491 IHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALS-CGLPEAPKNG--MVFGKEY 2547
Query: 825 LVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR--LPHCVSEESLACDNPGLPENG 882
VGT Y+C+ G+ L+ + T +TG +W++R P CV + +
Sbjct: 2548 TVGTKAMYSCSEGYHLQAGAEATAECLDTG--LWSNRNVPPQCVPVTCPDVSSISVEHGR 2605
Query: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
++++++ Y L +C G+ G+ IRC P C++
Sbjct: 2606 WRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
Score = 157 bits (398), Expect = 4e-38
Identities = 154/570 (27%), Positives = 244/570 (42%), Gaps = 71/570 (12%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRG 339
C+ P G ++S +P N+ CT+ +T + ++L +S L D ++LS+
Sbjct: 26 CTFQLHGPNGTVESPGFPY-GYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSV-- 82
Query: 340 VDGPTL--TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML---SCN 394
DGP + T I S T+S+ R D + H +L +C
Sbjct: 83 FDGPPQPENLRTRLTGFQLPATIVSAATTLSL--RLISDYAVSAQGFHATYEVLPSHTCG 140
Query: 395 FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASK--PHWSSQEPICSA-- 450
P R +G + G + C+LG+ L+G +LTC S+ W P C A
Sbjct: 141 NPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADD 200
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
CGG + + G + SP +P + + C WTI A G + L F L D +
Sbjct: 201 ACGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVT 259
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE---------- 560
G T S+L + S+P ++S N +R+ FTSD F+ +++
Sbjct: 260 G-TEGSSLWFTG---ASLP-APVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSR 314
Query: 561 --------------------AFEKGH--CYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
+GH C +P I + G SD + +G+ V+FTC+ G
Sbjct: 315 GVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSD--FRLGSSVQFTCNEG 372
Query: 598 HSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVVLSPNWPEPYVEGEDC 654
+ L QG I C+ V D + W+D P+CRA MC L +G++ SPN+P Y C
Sbjct: 373 YDL-QGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
Query: 655 IWKI-HVGEEKRIFLDIQFLNLSNS-DILTIYDG--DEVMPHILGQYLGNSGPQKLYSST 710
+W I + K I L + +L D LT+ DG D +L G S P + S+
Sbjct: 432 VWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTN 491
Query: 711 PDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARIT 770
+ + F +D + G GF +Y E+ + SC D P I + + G +
Sbjct: 492 HQMWLLFQTDGS----GSSLGFKASYEEIEQG-SCGD-PGIP-AYGRREGSRFHHGDTLK 544
Query: 771 YQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
++C P +++VG +TCQ + WS+ P C
Sbjct: 545 FECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Score = 156 bits (394), Expect = 1e-37
Identities = 188/753 (24%), Positives = 304/753 (40%), Gaps = 125/753 (16%)
Query: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
+A C + G I S +P NN +CT+ + G + L L DG +
Sbjct: 197 RADDACGGTLRGQSGIISSPHFPSEYHNN-ADCTWTILAELGDTIALVFIDFQLEDGYDF 255
Query: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
L + G +G +L + VI S N + ++F + + F YQ
Sbjct: 256 LEVTGTEGSSLWFTGAS---LPAPVISSK-NWLRLHFTSDGNHRQRGFSAQYQVKKQIEL 311
Query: 389 ------FMLS---------------------CNFPRRPDSGDVTVMDLHSGGVAHFHCHL 421
M S C P P+ G D G F C+
Sbjct: 312 KSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNE 371
Query: 422 GYELQGAKMLTCINASKPH--WSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
GY+LQG+K +TC+ S WS P+C A A G + SP++P + + C
Sbjct: 372 GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHC 431
Query: 480 IWTIEAPEGQK-LHLHFERL-LLHDKDRMTVHSG--QTNKSALLYDSLQTESVPFEGLLS 535
+W I A K + L FE L D +TV G ++ +LY L SVP + ++S
Sbjct: 432 VWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLY-ILTGTSVP-DLIVS 489
Query: 536 EGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCD 595
+ + + F +D + ++ F +E E+G C +P I ++ G ++F C
Sbjct: 490 TNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYG-RREGSRFHHGDTLKFECQ 548
Query: 596 PGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCI 655
P L G I C ++ W+ +P C C ++ +GVVLSPN+PE Y C+
Sbjct: 549 PAFELV-GQKAITC--QKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCV 605
Query: 656 WKIHVGEEKRIFLDIQFLNLS-NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLT 714
W I E RI L +++ D L I DG +LG + GN P + SS
Sbjct: 606 WLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVAR 665
Query: 715 IQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCD 774
++F +D + GK +GF + + R++ C D NG + +L G+ I++ CD
Sbjct: 666 LEFQTDHS---TGK-RGFNITF-TTFRHNECPDPGVPVNGKRFGDSLQL--GSSISFLCD 718
Query: 775 PGY-DIVGSDTLTC---QWDLSWSSD------------------------PPFCEKIMYC 806
G+ GS+T+TC + + W+S P F + + C
Sbjct: 719 EGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSC 778
Query: 807 -----TDPG------------EVDHST------RLISDPVLLV--GTTIQYTCNPGFVLE 841
PG EV++ T R S P++ V GT + P F++
Sbjct: 779 AWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQV-----PQFLIS 833
Query: 842 GSSLLTCY--SRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTF 899
S+ L + ++ + I ++ +S C +PG+P NG + + + G +TF
Sbjct: 834 TSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR--HGNDFYVGALVTF 891
Query: 900 MCYEGFELMGEVTIRCILGQPS-HWNGPLPVCK 931
C G+ L + C +P+ W+ LP C+
Sbjct: 892 SCDSGYTLSDGEPLEC---EPNFQWSRALPSCE 921
Score = 99.8 bits (247), Expect = 1e-20
Identities = 102/385 (26%), Positives = 160/385 (41%), Gaps = 57/385 (14%)
Query: 462 GRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNKSALLY 520
G V SP +P C WTI A E ++ L F+ L D D ++V G
Sbjct: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDGPPQP----- 89
Query: 521 DSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGN 576
++L+T F+ ++S T+ + SD A +A F+ +E C P + NG
Sbjct: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNG- 148
Query: 577 FTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCRA--MCGGEL 632
T+N+G V ++C+ G LE G A++ C + W+ P CRA CGG L
Sbjct: 149 -IQQGSTFNLGDKVRYSCNLGFFLE-GHAVLTCHAGSENSATWDFPLPSCRADDACGGTL 206
Query: 633 SAVAGVVLSPNWPEPYVEGEDCIWKI--HVGEE-KRIFLDIQFLNLSNSDILTIYDGDEV 689
+G++ SP++P Y DC W I +G+ +F+D Q + + +T +G +
Sbjct: 207 RGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSL 266
Query: 690 MPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG-KGQGFIMNYIEVSRNDSCSDL 748
+ G S P + SS L + F SD G Q + IE+ ++ +
Sbjct: 267 W------FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIEL-KSRGVKLM 319
Query: 749 PEIQNGWKTTSHTEL---------------VRGAR----------ITYQCDPGYDIVGSD 783
P N KT+ T++ RG R + + C+ GYD+ GS
Sbjct: 320 PSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSK 379
Query: 784 TLTC----QWDLSWSSDPPFCEKIM 804
+TC +WS P C M
Sbjct: 380 RITCMKVSDMFAAWSDHRPVCRARM 404
Score = 93.2 bits (230), Expect = 1e-18
Identities = 135/571 (23%), Positives = 219/571 (38%), Gaps = 70/571 (12%)
Query: 390 MLSCN-FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
++SC P P+ + + ++ G A F C+ GY L G+++ C+ + WS E C
Sbjct: 2655 IISCGELPIPPNGHRIGTLSVY-GATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRC 2711
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-----K 503
A G G + +Y + GS + G +L R+ D K
Sbjct: 2712 LAGHCGTPEPIVNGHINGENY--SYRGSV----VYQCNAGFRLIGMSVRICQQDHHWSGK 2765
Query: 504 DRMTV-----HSGQTNKSALLYDSLQTESVPFEGLLSE----GNTIRI-----EFTSDQA 549
V H G S + DS +V + + GN+ R+ +T
Sbjct: 2766 TPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLP 2825
Query: 550 RAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIEC 609
+ T G C +P I D +++ GT++ F+C+ GH L +G + C
Sbjct: 2826 HCSGT--------SVGVCGDPGIPAHGIRLGD-SFDPGTVMRFSCEAGHVL-RGSSERTC 2875
Query: 610 INVRDPYWNDTEPLCRAM-CGGE-LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIF 667
+ W+ ++P C + CG + A VV S + V +++ G
Sbjct: 2876 --QANGSWSGSQPECGVISCGNPGTPSNARVVFS----DGLVFSSSIVYECREGYYATGL 2929
Query: 668 LDIQFL-----NLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHS 719
L S+ + L I GD +P G LGN Y P ++ H
Sbjct: 2930 LSRHCSVNGTWTGSDPECLVINCGDPGIP-ANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
Query: 720 DPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDI 779
++ V + C P I NG S + + G+ +TY C GY +
Sbjct: 2989 --VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS--DFMWGSSVTYACLEGYQL 3044
Query: 780 VGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFV 839
TC+ + SW+ + P C + +C DPG R D +++ ++C+P V
Sbjct: 3045 SLPAVFTCEGNGSWTGELPQCFPV-FCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLV 3101
Query: 840 LEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTF 899
L GS C S T W+ P C+ C +PG+P+ G Q + Y G ++ F
Sbjct: 3102 LVGSPRRFCQSDGT----WSGTQPSCIDPTLTTCADPGVPQFGIQ-NNSQGYQVGSTVLF 3156
Query: 900 MCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
C +G+ L G T C+ W+G P C
Sbjct: 3157 RCQKGYLLQGSTTRTCLPNLT--WSGTPPDC 3185
Score = 82.4 bits (202), Expect = 2e-15
Identities = 51/164 (31%), Positives = 71/164 (43%), Gaps = 11/164 (6%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
+ YQC+ G+ ++G CQ D WS PFC ++ C PG HS +S VG
Sbjct: 2738 VVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC-VLVSCGHPGSPPHSQ--MSGDSYTVGA 2794
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYK 888
++Y+C L G+S C WT LPHC C +PG+P +G ++
Sbjct: 2795 VVRYSCIGKRTLVGNSTRMCGL----DGHWTGSLPHCSGTSVGVCGDPGIPAHGIRL--G 2848
Query: 889 RLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
+ PG + F C G L G C W+G P C V
Sbjct: 2849 DSFDPGTVMRFSCEAGHVLRGSSERTCQAN--GSWSGSQPECGV 2890
Score = 76.3 bits (186), Expect = 1e-13
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 11/166 (6%)
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G + + C+ G+ + GS TCQ + SWS P C ++ C +PG ++ + SD L+
Sbjct: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC-GVISCGNPGTPSNARVVFSDG-LV 2911
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI 885
++I Y C G+ G LL+ + GT WT P C+ + C +PG+P NG ++
Sbjct: 2912 FSSSIVYECREGYYATG--LLSRHCSVNGT--WTGSDPECL---VINCGDPGIPANGLRL 2964
Query: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Y +++T+ C G+ + + WNG PVCK
Sbjct: 2965 GNDFRY--NKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCK 3008
Score = 73.6 bits (179), Expect = 9e-13
Identities = 115/499 (23%), Positives = 179/499 (35%), Gaps = 112/499 (22%)
Query: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-P 451
C P P G G V F C G+ L+G+ TC + WS +P C
Sbjct: 2835 CGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTC--QANGSWSGSQPECGVIS 2892
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHSG 511
CG +P P N R+ G
Sbjct: 2893 CG------------NPGTPSNA-------------------------------RVVFSDG 2909
Query: 512 QTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY 571
S+++Y+ E GLLS ++ +T +C +P
Sbjct: 2910 LVFSSSIVYEC--REGYYATGLLSRHCSVNGTWTGSDPECLVI-----------NCGDPG 2956
Query: 572 IQ-NGNFTTSDPTYNIGTIVEFTCDPGHSLEQGP-AIIECINVRDPYWNDTEPLCRA-MC 628
I NG +D YN V + C PG+ +E +++ C +D WN T+P+C+A MC
Sbjct: 2957 IPANGLRLGNDFRYN--KTVTYQCVPGYMMESHRVSVLSC--TKDRTWNGTKPVCKALMC 3012
Query: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVG----EEKRIFLDIQFLNLSNSD----- 679
P P V G D +W V E ++ L F N
Sbjct: 3013 KPP----------PLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGEL 3062
Query: 680 --ILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYI 737
++ GD +P + G ++ + ++ F P ++ G + F +
Sbjct: 3063 PQCFPVFCGDPGVP--------SRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG 3114
Query: 738 EVSRND---------SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQ 788
S +C+D Q G + S V G+ + ++C GY + GS T TC
Sbjct: 3115 TWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQV-GSTVLFRCQKGYLLQGSTTRTCL 3173
Query: 789 WDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLE-GSSLLT 847
+L+WS PP C +C P H+ D + +G T+ Y+C GF L+ GS T
Sbjct: 3174 PNLTWSGTPPDCVP-HHCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRT 3231
Query: 848 CYSRETGTPIWTSRLPHCV 866
C + + WT + P C+
Sbjct: 3232 CKADGS----WTGKPPICL 3246
Score = 71.2 bits (173), Expect = 5e-12
Identities = 52/166 (31%), Positives = 71/166 (42%), Gaps = 16/166 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC--EKIMYCTDPGEVDHSTRLISDPVLLV 826
+++ C P +VGS CQ D +WS P C + C DPG + S V
Sbjct: 3092 VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQ-V 3150
Query: 827 GTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQIL 886
G+T+ + C G++L+GS+ TC T W+ P CV C P P +
Sbjct: 3151 GSTVLFRCQKGYLLQGSTTRTCLPNLT----WSGTPPDCVPHH---CRQPETPTHAN--- 3200
Query: 887 YKRLYLP--GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
L LP G +L + C EGF L G R S W G P+C
Sbjct: 3201 VGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS-WTGKPPIC 3245
Score = 63.9 bits (154), Expect = 7e-10
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 14/200 (7%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
C +L G V SP +P Y +C W I E+ RI L Q L D+L+++DG
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG 85
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
++ + G P + S+ L+++ SD A QGF Y EV + +C
Sbjct: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYA----VSAQGFHATY-EVLPSHTCG 140
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFCEK 802
+ + NG + S L G ++ Y C+ G+ + G LTC + +W P C
Sbjct: 141 NPGRLPNGIQQGSTFNL--GDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
Query: 803 IMYCTDPGEVDHSTRLISDP 822
C G + + +IS P
Sbjct: 199 DDAC--GGTLRGQSGIISSP 216
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C +PG + + + S +G ++Y+CN GF LEG ++LTC++ + W LP C
Sbjct: 139 CGNPGRLPNGIQQGS--TFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Query: 866 VSEES 870
++++
Sbjct: 197 RADDA 201
Score = 44.7 bits (104), Expect = 5e-04
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
+C P +P NG + + YL + ++F C G+ L G I C+ G WN P P+C
Sbjct: 1908 SCPEPAVPSNGVKTGER--YLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC 1964
Score = 37.7 bits (86), Expect = 0.056
Identities = 17/61 (27%), Positives = 29/61 (47%)
Query: 873 CDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
C P + N + + G+ + + C GF L+G + C LG + GP P+C+V
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
Query: 933 N 933
+
Sbjct: 2354 H 2354
Score = 37.0 bits (84), Expect = 0.095
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C+ E + RL SD VG +++ CN G+ L+GS + C W P C
Sbjct: 1735 CSSVPEPRYGKRLGSD--FSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
Query: 866 V-------SEESLACDNPGLPE 880
V +E +PG PE
Sbjct: 1793 VVPCGGNLTERRGTILSPGFPE 1814
Score = 34.3 bits (77), Expect = 0.62
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 766 GARITYQCDPGYDIVG-SDTLTCQWDLSWSSDPPFCEKI 803
G + Y C G+ + G S+ TC+ D SW+ PP C ++
Sbjct: 3210 GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEV 3248
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 258 bits (659), Expect = 2e-68
Identities = 181/539 (33%), Positives = 269/539 (49%), Gaps = 36/539 (6%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C S EG + S ++P NN EC Y + G G+ L+ +S L +G+ L +
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNH-ECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
Query: 339 -GVDG---PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSC 393
G D P T N+ L G ++ S +N + + F T D FQL Y +F ++ C
Sbjct: 1162 DGKDSSSRPLGTFTKNELL---GLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKC 1218
Query: 394 NFPRRPDSGDVTVMDLH-SGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPC 452
P P+ G + H + V + C+ GY + G+ LTC++ + W P C A C
Sbjct: 1219 EDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAEC 1278
Query: 453 GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLH---FERLLLHDKDRMTVH 509
GG +H AT GR+LSP YP + + C W IEA G+ + LH F+ + H D + V
Sbjct: 1279 GGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH--DILKVW 1336
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
G + LL + + S E + S N++ ++F SD + S F+I+F C +
Sbjct: 1337 DGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCND 1394
Query: 570 PYI-QNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDP-YWNDTEPLCRAM 627
P + QNG T + G V F CDPG+ L QG A I C+ + + +W P C A
Sbjct: 1395 PGMPQNG--TRYGDSREAGDTVTFQCDPGYQL-QGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
CGG L+ AGV+LSPN+P+PY G++C W++ V + I L + N+ S D L IY+G
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPA-GLIFGKGQGFIMNYIEVSRNDSC 745
++ ++G Y G+ P+++ SS L + F SD + GL GF + + E R ++C
Sbjct: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGL-----SGFAIEFKEKPR-EAC 1565
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPFC 800
D I NG T T+ G+ ITYQCD GY I+ ++TC SW P C
Sbjct: 1566 FDPGNIMNG--TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Score = 213 bits (542), Expect = 7e-55
Identities = 156/533 (29%), Positives = 251/533 (47%), Gaps = 30/533 (5%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSV----NLSDGELLS 336
CS +F+ G I S YP P N L C + + V G G+++QV S N E+
Sbjct: 1803 CSGNFTQRRGTILSPGYPE-PYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIHD 1861
Query: 337 IRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNF 395
V P L + T+ ++ S +N + ++F++ F L Y+ L+ C
Sbjct: 1862 GGDVTAPRLGSFSGTTVPA---LLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQE 1918
Query: 396 PRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGG 454
P P S + + D + V F C GY LQG ++C+ + W+ P+C A CGG
Sbjct: 1919 PALP-SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGG 1977
Query: 455 AVHNATIGRV-LSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQ 512
+ +T+G V LSP +P + + C W I P G H+ F + D + + +G
Sbjct: 1978 TL--STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP 2035
Query: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
+ S ++ T+ +P LLS + I F SD ++ F + ++A+E +C +P
Sbjct: 2036 YHTSPMIGQFSGTD-LP-AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPP 2093
Query: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
QNG SD Y++G V F C PG+ L P ++ C + + WN P C A CG
Sbjct: 2094 FQNGYMINSD--YSVGQSVSFECYPGYILIGHP-VLTCQHGINRNWNYPFPRCDAPCGYN 2150
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYDGDEVM 690
+++ G + SP +P+ Y +DCIW I V ++++ L + +D + ++DG +
Sbjct: 2151 VTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQN 2210
Query: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
LG + GN+ + YSST + ++FHSD F G F++N+ + C P
Sbjct: 2211 SPQLGVFSGNTALETAYSSTNQVLLKFHSD-----FSNGGFFVLNF-HAFQLKKCQPPPA 2264
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQW--DLSWSSDPPFCE 801
+ T + G + YQC PGY +VG+D LTC+ L + P CE
Sbjct: 2265 VPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2317
Score = 211 bits (536), Expect = 4e-54
Identities = 195/737 (26%), Positives = 305/737 (41%), Gaps = 84/737 (11%)
Query: 258 SQETTTSTIITTTVITTEQAPAL----CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVT 313
S+ T + T ++ P C + P G I S +YP+ +N C + +T
Sbjct: 385 SKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN-AHCVWVIT 443
Query: 314 VYTGYGV-ELQVKSVNLSDG-ELLSI--RGVDGPTLTVLANQTLLVEGQVIRSPTNTISV 369
V +L + L G + L++ G G T +VL T +I S +N + +
Sbjct: 444 TTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWL 503
Query: 370 YFRTFQDDGLGT--FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQ 426
+ ++ DD +G+ F+ YQ C P P G T G F C +EL
Sbjct: 504 HLQS--DDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELV 561
Query: 427 GAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAP 486
G +++TC ++ WS +P C C A+ G +LSP+YPE + C+W I +
Sbjct: 562 GERVITCQQNNQ--WSGNKPSCVFSCFFNF-TASSGIILSPNYPEEYGNNMNCVWLIISE 618
Query: 487 EGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTS 546
G ++HL F + + + + VP + L S G+ +R+EF S
Sbjct: 619 PGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQS 677
Query: 547 DQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAI 606
D + FNI + F + C++P I D + +G+ V F CD G QG
Sbjct: 678 DHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGD-RFLLGSSVSFHCDDGFVKTQGSES 736
Query: 607 IECI-NVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHV--GEE 663
I CI + W+ T P C A CGG L+A +GV+L P WP Y + C W I G
Sbjct: 737 ITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHS 796
Query: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAG 723
+I D +F N D L + DG ++G+Y G PQ L S+ + + F +D +
Sbjct: 797 IKITFD-RFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS- 854
Query: 724 LIFGKGQGFIMNYIEVS-RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGS 782
GF+++Y V+ +DSC D NG + + + +T+ CDPGY +
Sbjct: 855 ---RSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGI--RSTVTFSCDPGYTLSDD 909
Query: 783 DTLTCQWDLSWSSDPPFCEKI------------------------MYCTDPGEVDHSTRL 818
+ L C+ + W+ P C+ + + CT EV H +
Sbjct: 910 EPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGV 969
Query: 819 -----------------------ISDPVL-LVGTTIQYTCNPGFVLEGSSLLTCYSRETG 854
S+PV L G+ + +T G ++ L S
Sbjct: 970 QMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFIS---D 1026
Query: 855 TPIWTSRLPHCVSEESL-ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTI 913
I SE L CD+PG+P +I + + G+SLTF C+ G+ L G +
Sbjct: 1027 FSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFH--FGVGDSLTFSCFLGYRLEGATKL 1084
Query: 914 RCILGQPSHWNGPLPVC 930
C+ G W+ PLP C
Sbjct: 1085 TCLGGGRRVWSAPLPRC 1101
Score = 197 bits (502), Expect = 3e-50
Identities = 155/539 (28%), Positives = 240/539 (44%), Gaps = 34/539 (6%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLE---CTYNVTVYTGYGVELQVKSVNLSDGELL 335
A C ++ EG + S +YP +N+ C Y++TV + V Q + +L
Sbjct: 1624 APCGGQYTGSEGVVLSPNYP----HNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLA 1679
Query: 336 SIRGVDGPTLTVLANQTLLVEGQVIRSPT-NTISVYFRTFQDDGLGTFQLHYQAFMLS-- 392
+ +L++ + G+ + T N I + F F YQA +
Sbjct: 1680 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
Query: 393 --CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTC--INASKPHWSSQEPIC 448
C+ P G + +G + F C+ GY LQG+ L C + + W+ P C
Sbjct: 1740 TQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMT 507
PC G G +LSP YPE + CIW I EG + + D +
Sbjct: 1800 VVPCSGNFTQRR-GTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLE 1858
Query: 508 VHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
+H G + +A S +VP L S N + + F SD + AA+ F++ ++ C
Sbjct: 1859 IHDGG-DVTAPRLGSFSGTTVPAL-LNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAAC 1916
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
EP + + + D Y + ++ F C+PG++L QG + I C+ WN PLC A
Sbjct: 1917 QEPALPSNSIKIGD-RYMVNDVLSFQCEPGYTL-QGRSHISCMPGTVRRWNYPSPLCIAT 1974
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS---NSDILTIY 684
CGG LS + GV+LSP +P Y DC W+I + IQFLN S N D L I
Sbjct: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISL--PIGYGAHIQFLNFSTEANHDFLEIQ 2032
Query: 685 DGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDS 744
+G ++GQ+ G P L S+T + I F+SD + QGF + Y + +
Sbjct: 2033 NGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS----QNRQGFKLAY-QAYELQN 2087
Query: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL--SWSSDPPFCE 801
C D P QNG+ S + G ++++C PGY ++G LTCQ + +W+ P C+
Sbjct: 2088 CPDPPPFQNGYMINSDYSV--GQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2144
Score = 184 bits (467), Expect = 4e-46
Identities = 140/508 (27%), Positives = 234/508 (46%), Gaps = 21/508 (4%)
Query: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQ--VKSVNLSDGELLSIRG-VDGPTLT 346
G I S YP P +N L CT+ + G + L V ++ L G VD L
Sbjct: 1288 GRILSPGYPA-PYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDILL 1346
Query: 347 VLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQ-AFMLSCNFPRRPDSGDVT 405
+ + L E I S N++++ F + F + + + +CN P P +G
Sbjct: 1347 KEWSGSALPED--IHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRY 1404
Query: 406 VMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGRV 464
+G F C GY+LQG +TC+ + W P C A CGG + G +
Sbjct: 1405 GDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAACGGNL-TGPAGVI 1463
Query: 465 LSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDSL 523
LSP+YP+ + C W ++ + L F+ + D + ++ G+ + S L+ S
Sbjct: 1464 LSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLI-GSY 1522
Query: 524 QTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSDP 582
Q P E + S GN++ + F SD + S F I F+ + C++P I NG +D
Sbjct: 1523 QGSQAP-ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFDPGNIMNGTRVGTD- 1580
Query: 583 TYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVVL 640
+ +G+ + + CD G+ + P+ I C+ D P W+ P C A CGG+ + GVVL
Sbjct: 1581 -FKLGSTITYQCDSGYKILD-PSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGVVL 1638
Query: 641 SPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGN 700
SPN+P Y G+ C++ I V +E +F + + +D+ ++DG +L G+
Sbjct: 1639 SPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELFDGTHAQARLLSSLSGS 1698
Query: 701 SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSH 760
+ L +T + + S +G +G F+ + + + CS +PE + G + S
Sbjct: 1699 HSGETLPLATSNQILLRFSAKSG-ASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGS- 1756
Query: 761 TELVRGARITYQCDPGYDIVGSDTLTCQ 788
E G+ + ++C+PGY + GS L CQ
Sbjct: 1757 -EFSAGSIVRFECNPGYLLQGSTALHCQ 1783
Score = 183 bits (464), Expect = 8e-46
Identities = 172/671 (25%), Positives = 288/671 (42%), Gaps = 40/671 (5%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSI 337
A C + S G I S +P NN L+CT+ +++ GYG +Q + + ++ + L I
Sbjct: 1973 ATCGGTLSTLGGVILSPGFPGSYPNN-LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEI 2031
Query: 338 RGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCNFP 396
+ T ++ + + S T+ ++F + F+L YQA+ L +C P
Sbjct: 2032 QNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP 2091
Query: 397 RRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAV 456
+G + D G F C+ GY L G +LTC + +W+ P C APCG V
Sbjct: 2092 PPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV 2151
Query: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQTNK 515
+ G + SP +P+ + CIW I P G ++++F L D + V G
Sbjct: 2152 TSQN-GTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQN 2210
Query: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQN 574
S L + + + E S N + ++F SD + F + F AF+ C P +
Sbjct: 2211 SPQL--GVFSGNTALETAYSSTNQVLLKFHSDFSNGGF-FVLNFHAFQLKKCQPPPAVPQ 2267
Query: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE--L 632
T D + IG V++ C PG++L G I+ C + + P C A C
Sbjct: 2268 AEMLTEDDDFEIGDFVKYQCHPGYTLV-GTDILTCKLSSQLQFEGSLPTCEAQCPANEVR 2326
Query: 633 SAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQ-FLNLSNSDILTIYDGDEVMP 691
+ +GV+LSP +P Y + C W I V I + + F + D L ++DG
Sbjct: 2327 TGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQS 2386
Query: 692 HILGQYLGNSGPQKLYSS-TPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
+L GN Q ++S + L +++ +D A +GF + Y CS
Sbjct: 2387 PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHA----TSKKGFKIRYAA----PYCSLTHP 2438
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEKIMYC 806
++NG + T G+++ Y C PGY +VG TC+ + W S P C+ + C
Sbjct: 2439 LKNG-GILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS-C 2496
Query: 807 TDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS--RLPH 864
P + + + + + + Y C+ GF LE S T +E G +W++ + P
Sbjct: 2497 GIPESPGNGS--FTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDG--LWSNKGKPPT 2552
Query: 865 CVSEESLACDN--PGLPENG-YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS 921
C + +AC + L E+ ++++ L G + C G+ L G +RC
Sbjct: 2553 C---KPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTW 2609
Query: 922 HWNGPLPVCKV 932
+ P C+V
Sbjct: 2610 NIGDERPSCRV 2620
Score = 158 bits (399), Expect = 3e-38
Identities = 170/706 (24%), Positives = 280/706 (39%), Gaps = 83/706 (11%)
Query: 290 GYIDSSDYPLLP------LNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDG 342
G++ +S +LP + L C + + G+ +++ + + L +R
Sbjct: 761 GHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPA 820
Query: 343 PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRP 399
+ ++ Q + S N + + F T F +HY++ L SC P P
Sbjct: 821 SSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIP 880
Query: 400 DSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNA 459
+G D F C GY L + L C W+ P C A CGG +
Sbjct: 881 VNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVC--ERNHQWNHALPSCDALCGGYIQGK 938
Query: 460 TIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKS 516
+ G VLSP +P+ S C WTIE G+ + + F L HD +T +
Sbjct: 939 S-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPV 997
Query: 517 ALLYDSLQTESVPFEGLLSEGN-TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNG 575
A L S+ ++ GL GN T ++ F SD + + FNI F ++ C +P +
Sbjct: 998 ARLTGSVLPHTIK-AGLF--GNFTAQLRFISDFSISYEGFNITFSEYDLEPCDDPGVPAF 1054
Query: 576 NFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAV 635
+ + +G + F+C G+ LE G + C+ W+ P C A CG +
Sbjct: 1055 SRRIGFH-FGVGDSLTFSCFLGYRLE-GATKLTCLGGGRRVWSAPLPRCVAECGASVKGN 1112
Query: 636 AGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILG 695
G +LSPN+P Y +CI+KI K I L + L D L +YDG + LG
Sbjct: 1113 EGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYDGKDSSSRPLG 1172
Query: 696 QYLGNSGPQKLYSSTPD-LTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQN- 753
+ N + +ST + L ++F+++ + QGF + Y C D P I N
Sbjct: 1173 TFTKNELLGLILNSTSNHLWLEFNTNGS----DTDQGFQLTYTSFDL-VKCED-PGIPNY 1226
Query: 754 GWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC------QWD----------------- 790
G++ + Y C+PGY + GS+TLTC WD
Sbjct: 1227 GYRIRDEGHFT-DTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAA 1285
Query: 791 -----LSWSSDPPFCEKIMYCT-----DPG------------EVDHSTRLISDPVLLVGT 828
LS P+ + ++CT DPG E+ H + D +
Sbjct: 1286 TSGRILSPGYPAPY-DNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGPVDSDI 1344
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQI 885
++ + S + + + + S+ + + + C++PG+P+NG +
Sbjct: 1345 LLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTR- 1403
Query: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCI-LGQPSHWNGPLPVC 930
Y G+++TF C G++L G+ I C+ L W P C
Sbjct: 1404 -YGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 149 bits (375), Expect = 2e-35
Identities = 177/746 (23%), Positives = 292/746 (39%), Gaps = 112/746 (15%)
Query: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
+A C + I S +P NN +CT+ + G + L L +G +
Sbjct: 203 RAEGACGGTLRGTSSSISSPHFPSEYENN-ADCTWTILAEPGDTIALVFTDFQLEEGYDF 261
Query: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
L I G + P++ + + + VI S N + ++F + + F +Q
Sbjct: 262 LEISGTEAPSIWLTG---MNLPSPVISSK-NWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
Query: 389 -----------------FMLS----------CNFPRRPDSGDVTVMDLHSGGV-AHFHCH 420
+LS C P P++G D G F C
Sbjct: 318 KSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCE 377
Query: 421 LGYELQGAKMLTC--INASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQF 478
Y LQG+K +TC + + WS PIC A G+ G + SP+YP +
Sbjct: 378 DNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAH 437
Query: 479 CIWTIEAPEGQK-LHLHFERL-LLHDKDRMTV-HSGQTNKSALLYDSLQTESVPFEGLLS 535
C+W I + K + L FE L D +TV +G+ + + L SVP + ++S
Sbjct: 438 CVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVP-DLIVS 496
Query: 536 EGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCD 595
N + + SD + + F ++ EKG C +P I T ++ G + F C
Sbjct: 497 MSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGS-SFLHGDTLTFECP 555
Query: 596 PGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCI 655
L G +I C ++ W+ +P C C +A +G++LSPN+PE Y +C+
Sbjct: 556 AAFEL-VGERVITC--QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCV 612
Query: 656 WKIHVGEEKRIFLDIQFLNLS-NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLT 714
W I RI L ++ D L + D +LG + GN P +L SS +
Sbjct: 613 WLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVR 672
Query: 715 IQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCD 774
++F SD + G+GF + Y +N+ C D NG + + G+ +++ CD
Sbjct: 673 LEFQSDHS----TTGRGFNITYTTFGQNE-CHDPGIPINGRRFGD--RFLLGSSVSFHCD 725
Query: 775 PGY-DIVGSDTLTC---QWDLSWSSDPPFCE----------------------------- 801
G+ GS+++TC ++ WSS P CE
Sbjct: 726 DGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHC 785
Query: 802 ------------KIMYCTDPGEVDHSTRLISD-PVLLVGTTIQY--TCNPGFVLEGSSLL 846
KI + EV++ T + D P +Y T P F++ + +
Sbjct: 786 EWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFM 845
Query: 847 TCYSRETGTPIWTSRLPH--CVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEG 904
+ L H V+ ES +C +PG+P NG++ + + ++TF C G
Sbjct: 846 YLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHR--HGGDFGIRSTVTFSCDPG 903
Query: 905 FELMGEVTIRCILGQPSHWNGPLPVC 930
+ L + + C + WN LP C
Sbjct: 904 YTLSDDEPLVC--ERNHQWNHALPSC 927
Score = 145 bits (366), Expect = 2e-34
Identities = 172/696 (24%), Positives = 277/696 (39%), Gaps = 88/696 (12%)
Query: 279 ALCSVSFSNPEGYIDS----SDYPLLPLNNFLECTYNVTVYTGYGVE-----LQVKSVN- 328
A C + ++ G I S +YP+L +C + +TV G+GV LQ ++VN
Sbjct: 2145 APCGYNVTSQNGTIYSPGFPDEYPILK-----DCIWLITVPPGHGVYINFTLLQTEAVND 2199
Query: 329 ---LSDGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLH 385
+ DG + P L V + T L + S TN + + F + +G G F L+
Sbjct: 2200 YIAVWDGP-----DQNSPQLGVFSGNTAL---ETAYSSTNQVLLKFHSDFSNG-GFFVLN 2250
Query: 386 YQAFMLS-CNFPRRPDSGDVTVMD--LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWS 442
+ AF L C P ++ D G + CH GY L G +LTC +S+ +
Sbjct: 2251 FHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFE 2310
Query: 443 SQEPICSAPC-GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH 501
P C A C V + G +LSP YP N SQ C W+I+ + + +
Sbjct: 2311 GSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2370
Query: 502 DK-DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE 560
+ D + V G + +S LL L S N + + +++D A + F IR+
Sbjct: 2371 KQFDALEVFDGSSGQSPLLV-VLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
Query: 561 AFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY---- 616
A +C + + +G+ V + C PG+ + G + C R+P
Sbjct: 2430 A---PYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMV-GHSNATCR--RNPLGMYQ 2483
Query: 617 WNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS 676
W+ PLC+A+ G + + N + +++ H G ++ Q +
Sbjct: 2484 WDSLTPLCQAVSCGIPESPGNGSFTGN---EFTLDSKVVYECHEGF--KLESSQQATAVC 2538
Query: 677 NSDILTIYDGD--------------EVMPHILGQYLGNS----GPQKLYSSTPDLTIQFH 718
D L G ++ H++ + + S G Q L S +P ++
Sbjct: 2539 QEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPG----YY 2594
Query: 719 SDPAGLIFGKGQGF--IMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
+ L+ + G I + R SC L NG K + T V GA + C+ G
Sbjct: 2595 LEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT--VYGATAIFTCNTG 2652
Query: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNP 836
Y +VGS C + WS C +C P + + IS T+ Y CNP
Sbjct: 2653 YTLVGSHVRECLANGLWSGSETRC-LAGHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNP 2709
Query: 837 GFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGES 896
GF L G+S+ C W+ + P CV + C +PG P +G+ + +
Sbjct: 2710 GFRLVGTSVRICLQDHK----WSGQTPVCV---PITCGHPGNPAHGF--TNGSEFNLNDV 2760
Query: 897 LTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
+ F C G+ L G +C W+ PLP C+V
Sbjct: 2761 VNFTCNTGYLLQGVSRAQC--RSNGQWSSPLPTCRV 2794
Score = 136 bits (343), Expect = 9e-32
Identities = 148/570 (25%), Positives = 231/570 (40%), Gaps = 70/570 (12%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLS-DGELLSIRG 339
C P G I+S +P N+ CT+ + ++L + L D ++LS+
Sbjct: 32 CGGLVQGPNGTIESPGFPH-GYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSV-- 88
Query: 340 VDGPTLTVLANQTLLVEG----QVIRSPTNTISVYFRT-FQDDGLGTFQLHYQAFMLSCN 394
DG N + + G I S + ++++F T F G L+ +C
Sbjct: 89 YDGQPQQ--GNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
Query: 395 FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINA--SKPHWSSQEPICSAP- 451
P G + + G + C GY L+G +LTCI + + W P C A
Sbjct: 147 NPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEG 206
Query: 452 -CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
CGG + T + SP +P + C WTI A G + L F L + S
Sbjct: 207 ACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEIS 265
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFE---------- 560
G T ++ + S ++S N +R+ FTSD FN +F+
Sbjct: 266 G-TEAPSIWLTGMNLPSP----VISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSR 320
Query: 561 ----------------------AFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
A C +P I +NG SD + +G V+F+C+
Sbjct: 321 GVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFS-RVGANVQFSCEDN 379
Query: 598 HSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVVLSPNWPEPYVEGEDC 654
+ L QG I C V + W+D P+CRA CG L +GV+ SPN+P Y + C
Sbjct: 380 YVL-QGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHC 438
Query: 655 IWKIHVGE-EKRIFLDIQFLNLSNS-DILTIYDGDEV--MPHILGQYLGNSGPQKLYSST 710
+W I + +K I L + L D LT+ D +V +L G+S P + S +
Sbjct: 439 VWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMS 498
Query: 711 PDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARIT 770
+ + SD + G GF Y E+ + C D P I K T + + G +T
Sbjct: 499 NQMWLHLQSDDS---IG-SPGFKAVYQEIEKG-GCGD-PGIPAYGKRTG-SSFLHGDTLT 551
Query: 771 YQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
++C +++VG +TCQ + WS + P C
Sbjct: 552 FECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 115 bits (288), Expect = 2e-25
Identities = 147/586 (25%), Positives = 220/586 (37%), Gaps = 143/586 (24%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHS 510
CGG V G + SP +P C W I E ++ L F L D D ++V+
Sbjct: 32 CGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYD 90
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
GQ + L L +P ++S G+ + + FT+D A +A F +E C P
Sbjct: 91 GQPQQGNLKV-RLSGFQLP-SSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCGNP 148
Query: 571 -YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV--RDPYWNDTEPLCRA- 626
I G +NIG + ++C PG+ LE G AI+ CI W+ P CRA
Sbjct: 149 GEILKG--VLHGTRFNIGDKIRYSCLPGYILE-GHAILTCIVSPGNGASWDFPAPFCRAE 205
Query: 627 -MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKI--HVGEE-KRIFLDIQ------FLNLS 676
CGG L + + SP++P Y DC W I G+ +F D Q FL +S
Sbjct: 206 GACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEIS 265
Query: 677 NSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGF-IMN 735
++ +I+ G + P + SS L + F SD G F +
Sbjct: 266 GTEAPSIW------------LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Query: 736 YIEVSR--------------------------NDSCSDLPEIQNGWKTTSHTELVRGARI 769
IE+ +D C D +NG + S V GA +
Sbjct: 314 AIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV-GANV 372
Query: 770 TYQCDPGYDIVGSDTLTCQ----WDLSWSSDPPFCEK----------------------- 802
+ C+ Y + GS ++TCQ +WS P C
Sbjct: 373 QFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQY 432
Query: 803 --------IMYCTDPGEV------------DHSTRLISDPVLLVGTTIQYTCNPGFVLEG 842
++ TDP +V + T + D + T + +VL G
Sbjct: 433 EDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGD-----AGKVGDTRSVLYVLTG 487
Query: 843 SS---LLTCYSRETGTPIWTSRLPHCVSEESL---------------ACDNPGLPENGYQ 884
SS L+ S + +W H S++S+ C +PG+P G +
Sbjct: 488 SSVPDLIVSMSNQ----MWL----HLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKR 539
Query: 885 ILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
+L G++LTF C FEL+GE I C Q + W+G P C
Sbjct: 540 T--GSSFLHGDTLTFECPAAFELVGERVITC--QQNNQWSGNKPSC 581
Score = 90.1 bits (222), Expect = 9e-18
Identities = 130/617 (21%), Positives = 210/617 (34%), Gaps = 121/617 (19%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
++C P P G + + V +F C+ GY LQG C S WSS P C
Sbjct: 2737 ITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQC--RSNGQWSSPLPTCR- 2793
Query: 451 PCGGAVHNATIGRVLSPSYPENT--NGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
+ P + EN +G Q + E H LL +
Sbjct: 2794 ----------VVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCM 2843
Query: 509 HSGQTNKSA--LLYDSLQTESVPFEGLLSE-----GNTIRIEFTSDQARAASTFNIRFE- 560
+G ++S L S VP +L+ G + ++ + + E
Sbjct: 2844 ANGLWDRSLPKCLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQED 2903
Query: 561 -----------AFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIEC 609
G C +P D + +++ F+C+ GH L P
Sbjct: 2904 SHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDD-FKTKSLLRFSCEMGHQLRGSPERTCL 2962
Query: 610 INVRDPYWNDTEPLCRAM-CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFL 668
+N W+ +P+C A+ CG + G+++S +
Sbjct: 2963 LNGS---WSGLQPVCEAVSCGNPGTPTNGMIVSSDG------------------------ 2995
Query: 669 DIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPA----GL 724
+ S+S I ++G + + N + PD TI DP G+
Sbjct: 2996 ----ILFSSSVIYACWEGYKTSGLMTRHCTANG---TWTGTAPDCTIISCGDPGTLANGI 3048
Query: 725 IFGK------------GQGFIMNYIE-----------------VSRNDSCSDLPEIQNGW 755
FG G++M + V + C P +QNG
Sbjct: 3049 QFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNG- 3107
Query: 756 KTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHS 815
T ++ G+ I+Y C GY + S L+C+ W + P C + +C DPG +
Sbjct: 3108 -TVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV-FCGDPG-IPAE 3164
Query: 816 TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN 875
RL S + + + C F+L GSS C + T W+ P C+ C +
Sbjct: 3165 GRL-SGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGT----WSGIQPTCIDPAHNTCPD 3219
Query: 876 PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQD 935
PG P G Q R Y G ++ F C +G+ + G T C+ W+G + +
Sbjct: 3220 PGTPHFGIQ-NSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLT--WSG------IQTE 3270
Query: 936 SFEHALEVAEAAAETSL 952
HA E A +
Sbjct: 3271 CIPHACRQPETPAHADV 3287
Score = 82.4 bits (202), Expect = 2e-15
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
+ YQC+PG+ +VG+ C D WS P C I C PG H + +
Sbjct: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT-CGHPGNPAHG--FTNGSEFNLND 2759
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGY---QI 885
+ +TCN G++L+G S C S W+S LP C + C +PG EN Q
Sbjct: 2760 VVNFTCNTGYLLQGVSRAQCRSNGQ----WSSPLPTC---RVVNCSDPGFVENAIRHGQQ 2812
Query: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
+ + G S+ + C +GF L+G + C+ W+ LP C
Sbjct: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRSLPKC 2855
Score = 76.6 bits (187), Expect = 1e-13
Identities = 95/374 (25%), Positives = 137/374 (36%), Gaps = 88/374 (23%)
Query: 567 CYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQ-GPAIIECINVRDPYWNDTEPLC 624
C +P + NG +D T+N V + C+PG+ +E A I C +D WN ++P+C
Sbjct: 3038 CGDPGTLANGIQFGTDFTFN--KTVSYQCNPGYVMEAVTSATIRC--TKDGRWNPSKPVC 3093
Query: 625 RAMCGGELSAVAGVVLSPNWPEPY---VEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDIL 681
+A VL P P VEG D W + + + LS+S IL
Sbjct: 3094 KA------------VLCPQPPPVQNGTVEGSDFRWGSSIS-----YSCMDGYQLSHSAIL 3136
Query: 682 TIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSR 741
+ G P F DP G+ G Y
Sbjct: 3137 SC-----------------EGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTY----- 3174
Query: 742 NDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
+ + +QC + +VGS CQ D +WS P C
Sbjct: 3175 ------------------------KSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCI 3210
Query: 802 KIMY--CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWT 859
+ C DPG H S VG+T+ + C G+ ++GS+ TC + T + I T
Sbjct: 3211 DPAHNTCPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQT 3269
Query: 860 SRLPHCVSEESLACDNPGLPENGYQILYKRLYLP--GESLTFMCYEGFELMGEVTIRCIL 917
+PH AC P P + + + LP G +L + C+ GF L G R
Sbjct: 3270 ECIPH-------ACRQPETPAHAD---VRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCK 3319
Query: 918 GQPSHWNGPLPVCK 931
W G PVCK
Sbjct: 3320 AD-MKWTGKSPVCK 3332
Score = 46.6 bits (109), Expect = 1e-04
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
AC P LP N +I + Y+ + L+F C G+ L G I C+ G WN P P+C
Sbjct: 1915 ACQEPALPSNSIKIGDR--YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC 1971
Score = 46.2 bits (108), Expect = 2e-04
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPG + + TR+ +D +G+TI Y C+ G+ + S +TC G P W LP C
Sbjct: 1565 CFDPGNIMNGTRVGTD--FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Score = 36.2 bits (82), Expect = 0.16
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 870 SLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL--GQPSHWNGPL 927
S C NPG G +L+ + G+ + + C G+ L G + CI+ G + W+ P
Sbjct: 142 SHTCGNPGEILKG--VLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
Query: 928 PVCK 931
P C+
Sbjct: 200 PFCR 203
Score = 35.8 bits (81), Expect = 0.21
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPG + TR G T+ + C+PG+ L+G + +TC W P C
Sbjct: 1392 CNDPGMPQNGTRYGDSRE--AGDTVTFQCDPGYQLQGQAKITCVQLNNRF-FWQPDPPTC 1448
Query: 866 VS 867
++
Sbjct: 1449 IA 1450
Score = 34.3 bits (77), Expect = 0.62
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL---GQPSHWNGPLP 928
AC +PG NG ++ + G ++T+ C G++++ +I C++ G+PS W+ LP
Sbjct: 1564 ACFDPGNIMNGTRVGTD--FKLGSTITYQCDSGYKILDPSSITCVIGADGKPS-WDQVLP 1620
Query: 929 VC 930
C
Sbjct: 1621 SC 1622
Score = 33.9 bits (76), Expect = 0.81
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 873 CDNPGLPENGYQI--LYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLP 928
C +PG+PENG + + R+ G ++ F C + + L G +I C + + W+ P
Sbjct: 349 CPDPGIPENGRRAGSDFSRV---GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRP 405
Query: 929 VCK 931
+C+
Sbjct: 406 ICR 408
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 233 bits (595), Expect = 5e-61
Identities = 167/515 (32%), Positives = 247/515 (47%), Gaps = 18/515 (3%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C S +N EG + S +YPL NN EC Y++ V G G+ + ++ +L+ G++L I
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1257
Query: 339 -GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFP 396
G D T + A + G + S +N + + F + + FQL Y +F LS C P
Sbjct: 1258 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1317
Query: 397 RRPDSG-DVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGA 455
P G ++ +G + C+ GY L G+ +L C+ + W P C A CGG
Sbjct: 1318 GIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1377
Query: 456 VHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTN 514
+ GR+LSP YP + + C+W IE G + L F D + V G
Sbjct: 1378 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1437
Query: 515 KSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQN 574
LL + + +P EG+ S N + I+F +D + S F I+F + C +P +
Sbjct: 1438 NDMLLKE-ISGSLIP-EGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
Query: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLCRAMCGGELS 633
N T + G V F CDPG+ L QG I CI V + Y W + P+C A CGG L+
Sbjct: 1496 -NGTRNGDGREPGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1553
Query: 634 AVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTIYDGDEVMPH 692
+G +LSPN+P PY DC W I V + I L I F N D L IYDG +
Sbjct: 1554 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1613
Query: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQ 752
++G + + P+++ SS+ + + F SD + GF + Y + +SC D I
Sbjct: 1614 LIGSFQDSKLPERIESSSNTMHLAFRSDGS----VSYTGFHLEY-KAKLRESCFDPGNIM 1668
Query: 753 NGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC 787
NG + +L G+ +TY CD GY + G TLTC
Sbjct: 1669 NGTRLGMDYKL--GSTVTYYCDAGYVLQGYSTLTC 1701
Score = 228 bits (580), Expect = 3e-59
Identities = 191/714 (26%), Positives = 306/714 (42%), Gaps = 87/714 (12%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGV 340
C + +G I S YP P +N L C + +TV G G+++QV S ++ S+
Sbjct: 1899 CGGILTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFY 1956
Query: 341 DG-----PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCN 394
DG P L + T+ ++ S +N + + F++ F L Y A L SC
Sbjct: 1957 DGGDNNAPRLGSYSGTTI---PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 2013
Query: 395 FPRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
P+ P SG + + D + G V F C GY LQG +TC+ W+ PIC A CG
Sbjct: 2014 EPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2072
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQ 512
GA+ + + G +LSP +P N S C WTI P G +HL F D + V SG
Sbjct: 2073 GAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2131
Query: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
+ S ++ L +P L S + + F SD ++ F+I ++A++ C +P
Sbjct: 2132 SETSTVI-GRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2189
Query: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+NG +D + +G + F C PG++L G + + C++ WN P C A+CGG
Sbjct: 2190 FRNGFVIGND--FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGN 2246
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN-SDILTIYDGDEVM 690
++A+ G + SP +P+ Y +DC W + V I+++ L D +T++DG +
Sbjct: 2247 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2306
Query: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
+GQ+ GN+ + +YS++ + I+FHSD F F+++Y + C P
Sbjct: 2307 SPQIGQFSGNTALESVYSTSNQILIKFHSD-----FTTSGFFVLSY-HAYQLRVCQPPPP 2360
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEKIMYCTD 808
+ N T E G I YQC PG+ +VG+ LTC+ L PP C+ + +
Sbjct: 2361 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2420
Query: 809 -----------PGEVDHSTRL--------------------------------------I 819
PG D L I
Sbjct: 2421 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI 2480
Query: 820 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP 879
PV L+ + Y+ G + +S + G R+ + + C P P
Sbjct: 2481 QSPV-LISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESP 2535
Query: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH--WNGPLPVCK 931
+GY I L + + C GF L+G+ + C + W+ P+P C+
Sbjct: 2536 PHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Score = 216 bits (549), Expect = 1e-55
Identities = 182/671 (27%), Positives = 290/671 (43%), Gaps = 40/671 (5%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNF---LECTYNVTVYTGYGVELQVKSVNLSDGEL- 334
A C + S+ G I S +P N+ L+CT+ + + G+GV LQ VN S +
Sbjct: 2069 AQCGGAMSDFSGVILSPGFP----GNYPSSLDCTWTINLPIGFGVHLQF--VNFSTETIH 2122
Query: 335 --LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML- 391
L +R T TV+ + + S T+ S+YF + F + YQA+ L
Sbjct: 2123 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
SC PR +G V D G F C GY L G LTC++ +W+ P C A
Sbjct: 2183 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2242
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHS 510
CGG + A G + SP YP+ Q C W + P G ++++F L D +TV
Sbjct: 2243 CGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2301
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
G S + + + E + S N I I+F SD + F + + A++ C P
Sbjct: 2302 GPDQNSPQIGQF--SGNTALESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPP 2358
Query: 571 Y-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC- 628
+ N T D + IG I+ + C PG +L G AI+ C + P+C+ +C
Sbjct: 2359 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCP 2417
Query: 629 GGELSAVA-GVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
EL + GV+LSP +P+ Y + C W I V + I + ++F D+L +YDG
Sbjct: 2418 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2477
Query: 687 DEVMPHILGQYLGN-SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
+ +L G+ S + S+ ++ +Q+ +D +GF + YI C
Sbjct: 2478 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN----NKKGFRIRYIAFY----C 2529
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL----SWSSDPPFCE 801
S +G+ S T + + + CD G+ +VG + C+ +W + P C+
Sbjct: 2530 STPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
I C P + L +D LVGT + Y CN G+ L L T + GT ++
Sbjct: 2589 AIS-CGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2645
Query: 862 LPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS 921
P CV + ++ L ++I+ Y + F C G+ +G +I C+
Sbjct: 2646 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTW 2705
Query: 922 HWNGPLPVCKV 932
W P C++
Sbjct: 2706 SWRNERPYCQI 2716
Score = 210 bits (535), Expect = 5e-54
Identities = 204/718 (28%), Positives = 307/718 (42%), Gaps = 88/718 (12%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
A C + + G+I S ++P P + +C + +TV Y + L S ++ + L I
Sbjct: 1546 APCGGNLTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1604
Query: 338 RGVDGPTLTVLANQTLLVEGQV------IRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
DGP +N L+ Q I S +NT+ + FR+ F L Y+A +
Sbjct: 1605 --YDGPD----SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1658
Query: 392 -SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASKPHWSSQEPIC 448
SC P +G MD G ++C GY LQG LTCI + +P W+ P C
Sbjct: 1659 ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
APCG + G VLSP+YP+N + C+++I P+ + F D + V
Sbjct: 1719 HAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEV 1777
Query: 509 HSGQTNKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
+ G T +S+LL S ES+P LS GN I I FTS A F+ ++A +
Sbjct: 1778 YDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPRT 1833
Query: 566 HCYE----PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WND 619
+ P + G ++ + +G+ V F C+PG+ L G I C V + WND
Sbjct: 1834 SSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWND 1890
Query: 620 TEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNS 678
+ P C CGG L+ G +LSP +PEPY +C+WKI V E I + + F N
Sbjct: 1891 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1950
Query: 679 DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
D L YDG + LG Y G + P L S++ +L + F SD I GF + Y
Sbjct: 1951 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD----ISVSAAGFHLEYTA 2006
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ DSC + +G K + G +++QCD GY + G +TC W+
Sbjct: 2007 IGL-DSCPEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 2063
Query: 797 PPFC------------EKIMYCTDPGEVDHS---TRLISDPVLLVGTTIQYTCNPGFVLE 841
P C I+ PG S T I+ P+ G +Q+ +
Sbjct: 2064 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF-GVHLQFVNFSTETIH 2122
Query: 842 GSSLLTCYSRETGT-------PIWTSRLPHCVSEESLACDNP-GLPENGYQILYKRLYLP 893
+ S ET T P S L E SL + + G+ I+Y+ L
Sbjct: 2123 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2182
Query: 894 --------------------GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
G++++F C+ G+ L+G + C+ G +WN PLP C+
Sbjct: 2183 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Score = 203 bits (517), Expect = 6e-52
Identities = 158/526 (30%), Positives = 246/526 (46%), Gaps = 29/526 (5%)
Query: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPT----L 345
G I S YP P +N L C + + V G V LQ + + + +R DGP L
Sbjct: 1384 GRILSPGYPF-PYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDI-LRVWDGPPENDML 1441
Query: 346 TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFPRRPDSGDV 404
+ +L+ EG I S N +++ F T F + + + + + C P P +G
Sbjct: 1442 LKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTR 1499
Query: 405 TVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGR 463
G F C GYELQG + +TCI + W P+C APCGG + ++ G
Sbjct: 1500 NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSS-GF 1558
Query: 464 VLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDS 522
+LSP++P S+ C WTI + L F + D + ++ G + S L+ S
Sbjct: 1559 ILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLI-GS 1617
Query: 523 LQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSD 581
Q +P E + S NT+ + F SD + + + F++ ++A + C++P I NG D
Sbjct: 1618 FQDSKLP-ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD 1676
Query: 582 PTYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVV 639
Y +G+ V + CD G+ L QG + + CI D P WN P C A CG + G V
Sbjct: 1677 --YKLGSTVTYYCDAGYVL-QGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1733
Query: 640 LSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG 699
LSPN+P+ Y G +C++ I V +E +F F S D++ +YDG +L G
Sbjct: 1734 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1793
Query: 700 -NSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT 758
+SG SS +TI+F S G I KG F+ + + + CS +PE + G +
Sbjct: 1794 SHSGESLPLSSGNQITIRFTS--VGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG 1851
Query: 759 SHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFC 800
+ E G+ + + C+PGY + GS + C+ W+ P C
Sbjct: 1852 N--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1895
Score = 201 bits (511), Expect = 3e-51
Identities = 203/744 (27%), Positives = 310/744 (41%), Gaps = 87/744 (11%)
Query: 252 GSASEESQETTTSTIITTTVITTEQAP---ALCSVSFSNPEGYIDSSDYPLLPLNNFLEC 308
G + ET T ++ V+ + P A C FS P G I S +P + L C
Sbjct: 823 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY-YKDSLNC 881
Query: 309 TYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTN 365
+ + G+ +++ + + ++L + DGP L +L + Q + S +N
Sbjct: 882 EWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLLGSYNGTQVPQFLFSSSN 939
Query: 366 TISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLG 422
I + F T F++HY++ + SC P P G D G F C G
Sbjct: 940 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 999
Query: 423 YELQGAKMLTCINASKPHWSSQE-PICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIW 481
Y L + L C K HW S P C A CGG V + G +LSP YPE S C W
Sbjct: 1000 YRLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPS-GTILSPGYPEFYPNSLNCTW 1055
Query: 482 TIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
T++ G+ + +F L HD +T + T A L S ++ GL
Sbjct: 1056 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTIN-AGLYGNFR 1114
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
++ F SD + + FNI F + C +P I Q G+ + + IG + F+C G
Sbjct: 1115 A-QLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN--FGIGDTLTFSCSSG 1171
Query: 598 HSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWK 657
+ LE G + I C+ W+ P C A CG + G++LSPN+P Y +CI+
Sbjct: 1172 YRLE-GTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYS 1230
Query: 658 IHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPD-LTIQ 716
I V K I + + +L+ D+L IYDG + H+LG + G S SST + L ++
Sbjct: 1231 IQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLE 1290
Query: 717 FHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
F+SD G +GF + Y + C D Q G+K + G+ I Y C+PG
Sbjct: 1291 FNSDTE----GTDEGFQLVYTSFELS-HCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPG 1344
Query: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS---------------- 820
Y + GS L C + D P I C + + S R++S
Sbjct: 1345 YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWM 1404
Query: 821 ---DPVLLVGTTIQYTC--------------------------NPGFVLEG-SSLLTCYS 850
DP +V ++Q+ + + EG S L +
Sbjct: 1405 IEVDPGNIV--SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVT 1462
Query: 851 RETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFEL 907
+ T + S+ + S + AC +PG+P NG + R PG+++ F C G+EL
Sbjct: 1463 IQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYEL 1520
Query: 908 MGEVTIRCILGQPSH-WNGPLPVC 930
GE I CI + + W PVC
Sbjct: 1521 QGEERITCIQVENRYFWQPSPPVC 1544
Score = 170 bits (431), Expect = 6e-42
Identities = 183/719 (25%), Positives = 297/719 (41%), Gaps = 98/719 (13%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSIRG 339
C +F+ P G + S DYP NN L C + + G + L +L S + L+++
Sbjct: 681 CLSNFTAPMGTVLSPDYPEGYGNN-LNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 739
Query: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
D P +L T + S ++ + + F+ F + Y F C P
Sbjct: 740 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 799
Query: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
P + + G C G+ + QG + +TCI K WS P C APCGG
Sbjct: 800 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH- 858
Query: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
+A G +LSP +P S C W IEA G + + FER + D + VH G
Sbjct: 859 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 918
Query: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG--HCYEPYIQ 573
S LL S VP + L S N I + FT+D +R+ + F I +E+ C +P I
Sbjct: 919 SPLL-GSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 976
Query: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+G D ++IG+ V F+CD G+ L + P + E ++ +W+ P C A+CGG+
Sbjct: 977 VHGRRYGHD--FSIGSTVSFSCDSGYRLSHEEPLLCE----KNHWWSHPLPTCDALCGGD 1030
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYD----- 685
+ +G +LSP +PE Y +C W + V K + + +L + D L I +
Sbjct: 1031 VRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT 1090
Query: 686 -------GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
G ++ P I GN Q + S D +I + +GF + + E
Sbjct: 1091 QPLARLTGSDLPPTINAGLYGNFRAQLRFIS--DFSISY------------EGFNITFSE 1136
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ + C D Q G + + + G +T+ C GY + G+ + C WS+
Sbjct: 1137 YNL-EPCEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAP 1193
Query: 797 PPFC-----------EKIMYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCN-----PGFV 839
P C E I+ + P +++ I + G I + G V
Sbjct: 1194 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV 1253
Query: 840 LE----------------GSSLLTCYSRETGTPIWTS------------RLPHCVSEESL 871
L+ G+S+ T +W +L + S E
Sbjct: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY-TSFELS 1312
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
C++PG+P+ GY+I + + G ++ + C G+ L G ++C+ G+ W+ PLP C
Sbjct: 1313 HCEDPGIPQFGYKI-SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1370
Score = 134 bits (336), Expect = 6e-31
Identities = 113/418 (27%), Positives = 178/418 (42%), Gaps = 22/418 (5%)
Query: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPICSA 450
C P P++G D G F C Y LQGAK +TC ++ WS P+C
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQK-LHLHFERLLLH-DKDRMTV 508
G+ G SP++P + + C+W I A K + ++FE L D +T+
Sbjct: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 565
Query: 509 -HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G+ + L VP + ++S + + + +D++ + F + ++ EK C
Sbjct: 566 GDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
+P D N ++ F C G L G I C + W+ P+C
Sbjct: 625 GDPGTPLYGIREGDGFSN-RDVLRFECQFGFELI-GEKSIVC--QENNQWSANIPICIFP 680
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYDG 686
C +A G VLSP++PE Y +CIW I RI L +L S D L + DG
Sbjct: 681 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 740
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
D ILG + G P L S++ L ++F +D + G+GF + Y N+ C
Sbjct: 741 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHS----MSGRGFNITYNTFGHNE-CP 795
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGY-DIVGSDTLTC---QWDLSWSSDPPFC 800
D N + + +L G+ I+ C+ G+ G++T+TC + WS P C
Sbjct: 796 DPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 132 bits (332), Expect = 2e-30
Identities = 175/717 (24%), Positives = 286/717 (39%), Gaps = 84/717 (11%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSD-GELLSI 337
ALC + + G I S YP NF +C + V V G G+ + + + +++
Sbjct: 2241 ALCGGNITAMNGTIYSPGYPD-EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITV 2299
Query: 338 -RGVD--GPTLTVLANQTLLVEGQVIRSPTNTISVYFRT-FQDDGLGTFQLHYQAFMLS- 392
G D P + + T L + + S +N I + F + F G F L Y A+ L
Sbjct: 2300 WDGPDQNSPQIGQFSGNTAL---ESVYSTSNQILIKFHSDFTTSGF--FVLSYHAYQLRV 2354
Query: 393 CNFPRRPDSGDVTVMD--LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
C P + ++ D G + + C G+ L G +LTC + P+C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 451 PC-GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
C + + G +LSP YP++ Q C W+I +G + + E + D + V
Sbjct: 2415 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2474
Query: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
+ G +S +L S F + S G+ + +++++D F IR+ AF +C
Sbjct: 2475 YDGPNIQSPVLISLSGDYSSAFN-ITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCS 2530
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLCRA 626
P + S + ++V + CD G L G + C Y W+ P C+A
Sbjct: 2531 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQA 2589
Query: 627 M-CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVG---EEKRIFL-----DIQFLNLSN 677
+ CG + G +L+ + Y+ G + + G K + D + N +
Sbjct: 2590 ISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2645
Query: 678 SDILTIYDGDEVMPHIL--GQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIM- 734
+ + + IL G++ +G Y + + F DP G G I
Sbjct: 2646 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTK----VVFSCDPG--YHGLGPASIEC 2699
Query: 735 --NYIEVSRND-------SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTL 785
N RN+ SC +LP NG K + T G+ + CD G+ +VGS
Sbjct: 2700 LPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVR 2757
Query: 786 TCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSL 845
C WS C +C P E+ + ++I + T + Y CNPGF L GSS+
Sbjct: 2758 ECLSSGLWSESETRC-LAGHCGIP-ELIVNGQVIGENYGYRDTVV-YQCNPGFRLIGSSV 2814
Query: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP------ENGYQILYKRLYLPGESLTF 899
C W+ +LP CV ++C +PG P NG+ + +TF
Sbjct: 2815 RICQQDHN----WSGQLPSCV---PVSCGHPGSPIYGRTSGNGFNF--------NDVVTF 2859
Query: 900 MCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGN 956
C G+ + G +C + W+ P P+CKV S A + E+ +E GN
Sbjct: 2860 SCNIGYLMQGPTKAQCQANR--QWSHPPPMCKVVNCSDPGI--PANSKRESKIEHGN 2912
Score = 93.6 bits (231), Expect = 9e-19
Identities = 133/594 (22%), Positives = 216/594 (36%), Gaps = 72/594 (12%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+SC P P G + + V F C++GY +QG C + WS P+C
Sbjct: 2833 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMCKV 2890
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
V+ + G + F T+ + + F +L + +
Sbjct: 2891 -----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL-----ICQPN 2940
Query: 511 GQTNK---SALLYDSLQTESVPFEGLLSE----GNTIRIEFTSD-----QARAASTFNIR 558
GQ +K ++ D P L E G+T+ T Q+ N
Sbjct: 2941 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 3000
Query: 559 FEAFEK-------GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECIN 611
+ + G C +P G+ + + + + V + CD G+ L G C+
Sbjct: 3001 WSGSQPHCSGDATGTCGDPGTP-GHGSRQESNFRTKSTVRYACDTGYILH-GSEERTCL- 3057
Query: 612 VRDPYWNDTEPLCRAM-CG-------GELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
+ W +P C+A+ CG G++ + G S + +EG I G
Sbjct: 3058 -ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGY-----ILSGPS 3111
Query: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSD 720
R + + + I GD +P G G+ G Y P T++ +
Sbjct: 3112 VRQCTANGTWSGTLPNCTIISCGDPGIP-ANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3170
Query: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
G + R +C P+I NG T G I+Y C PGY++
Sbjct: 3171 RIRTCTINGTW--SGVMPTCRAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELS 3226
Query: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
LTC + +WS + P C +C DPG R + + + ++CN F+L
Sbjct: 3227 FPAVLTCVGNGTWSGEVPQCLP-KFCGDPGIPAQGKR--EGKSFIYQSEVSFSCNFPFIL 3283
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
GSS C + T W+ PHC+ +C+NPG+P +G Q + G + F
Sbjct: 3284 VGSSTRICQADGT----WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFH 3338
Query: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEG 954
C +G L G T C+ W+G P C H+ + E A ++ G
Sbjct: 3339 CKKGHLLQGSTTRTCL--PDLTWSGIQPEC------IPHSCKQPETPAHANVVG 3384
Score = 81.3 bits (199), Expect = 4e-15
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHS 510
CGG + G + SP +P C W I A E ++ + F+ L ++ D ++++
Sbjct: 25 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD 83
Query: 511 GQTNKSALLYDSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G + + + +T F + S + + TSD A +A F + +E + C
Sbjct: 84 GHPHPT-----NFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCR 625
P + +++G + ++C G+ L+ P + CI +V W+ P+CR
Sbjct: 139 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLT-CIANSVNTASWDFPVPICR 196
Query: 626 A--MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE----KRIFLDIQ------FL 673
A CGG + +G++ SP++P Y DC W I V E IF D Q +L
Sbjct: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI-VAEPGDTISLIFTDFQMEEKYDYL 255
Query: 674 NLSNSDILTIY-DGDEVMPHIL 694
+ S+ TI+ G + P I+
Sbjct: 256 EIEGSEPPTIWLSGMNIPPPII 277
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/532 (21%), Positives = 189/532 (35%), Gaps = 85/532 (15%)
Query: 387 QAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEP 446
+ M+ C P P + ++ G H+ C L G TC HWS +P
Sbjct: 2949 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTC--QLNGHWSGSQP 3006
Query: 447 ICSAPCGGAVHN-----------------ATIGRVLSPSYPENTNGSQFCI----WTIEA 485
CS G + +T+ Y + + + C+ WT
Sbjct: 3007 HCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQ 3066
Query: 486 PEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFT 545
PE + + + K + G T S+++Y + EG + G ++R
Sbjct: 3067 PECKAVQCGNPGTTANGK--VFRIDGTTFSSSVIYSCM-------EGYILSGPSVR---- 3113
Query: 546 SDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPA 605
Q A T++ C +P I D Y +G V + C PG+++E +
Sbjct: 3114 --QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVVGQNVSYMCQPGYTMELNGS 3170
Query: 606 IIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKR 665
I + W+ P CRA+ P +EG + W +
Sbjct: 3171 RIRTCTINGT-WSGVMPTCRAVT---------CPTPPQISNGRLEGTNFDWGFSIS---- 3216
Query: 666 IFLDIQFLNLSNSDILTI-----YDGDEVMPHILGQYLGN---------SGPQKLYSSTP 711
++ LS +LT + G+ +P L ++ G+ G +Y S
Sbjct: 3217 -YICSPGYELSFPAVLTCVGNGTWSGE--VPQCLPKFCGDPGIPAQGKREGKSFIYQSEV 3273
Query: 712 DLTIQFHSDPAGLIF------GKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR 765
+ F G G G + IE ++ SC + ++G + + V
Sbjct: 3274 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT-SCENPGVPRHGSQNNTFGFQV- 3331
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G+ + + C G+ + GS T TC DL+WS P C I + E ++ +
Sbjct: 3332 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC--IPHSCKQPETPAHANVVGMDLPS 3389
Query: 826 VGTTIQYTCNPGFVLE-GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
G T+ YTC PGF L G+ C S T WT ++P C + + +P
Sbjct: 3390 HGYTLIYTCQPGFFLAGGTEHRVCRSDNT----WTGKVPICEAGSKILVKDP 3437
Score = 70.1 bits (170), Expect = 1e-11
Identities = 109/455 (23%), Positives = 162/455 (35%), Gaps = 102/455 (22%)
Query: 382 FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASK 438
F+++Y+ S C P P G + G + C GY L G LTCI + +
Sbjct: 126 FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNT 185
Query: 439 PHWSSQEPICSA--PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
W PIC A CGG + ++ G + SPS+P + + C WTI A G + L F
Sbjct: 186 ASWDFPVPICRAEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFT 244
Query: 497 RLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFN 556
+ +K YD L+ E SE TI + S N
Sbjct: 245 DFQMEEK----------------YDYLEIEG-------SEPPTIWL----------SGMN 271
Query: 557 IRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY 616
I P I N N+ + F D H A PY
Sbjct: 272 IP----------PPIISNKNWLR----------LHFVTDSNHRYRGFSA---------PY 302
Query: 617 WNDTEPLCRAMCGGELS----AVAGVVLSPNWPEPYVEGEDCIWKIH-VGEEKRIFLDIQ 671
+ L GEL G + + P IH + EE+R +Q
Sbjct: 303 -QGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQR----VQ 357
Query: 672 FLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKG 729
+L NS + D + PH P+ + T +L + H + F K
Sbjct: 358 VTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDF-KS 416
Query: 730 QGF-------------IMNYIEV-SRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDP 775
+GF I+N + + ++ C D E +NG + S L G+ + + CD
Sbjct: 417 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDE 474
Query: 776 GYDIVGSDTLTCQ----WDLSWSSDPPFCEKIMYC 806
Y + G+ ++TCQ +WS P C K+ C
Sbjct: 475 DYVLQGAKSITCQRIAEVFAAWSDHRPVC-KVKTC 508
Score = 70.1 bits (170), Expect = 1e-11
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
+ YQC+PG+ ++GS CQ D +WS P C + C PG + S
Sbjct: 2799 VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-CGHPGSPIYGR--TSGNGFNFND 2855
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQ--IL 886
+ ++CN G++++G + C + W+ P C + + C +PG+P N + +
Sbjct: 2856 VVTFSCNIGYLMQGPTKAQCQANRQ----WSHPPPMC---KVVNCSDPGIPANSKRESKI 2908
Query: 887 YKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS-HWNGPLPVC 930
+ G + + C G+ L G + C QP+ W+ PLP C
Sbjct: 2909 EHGNFTYGTVVFYDCNPGYFLFGSSVLIC---QPNGQWDKPLPEC 2950
Score = 62.4 bits (150), Expect = 2e-09
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 14/200 (7%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
CGG L + G + SP +P Y G +C W I E RI + Q L D L++YDG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
+ + G P + S+ +++ SD A GF + Y E+ ++ SC
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA----VSAHGFKVYYEEL-QSSSCG 139
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEK 802
+ G T G +I Y C GY + G LTC + SW P C
Sbjct: 140 NPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
Query: 803 IMYCTDPGEVDHSTRLISDP 822
C G + S+ +IS P
Sbjct: 198 EDAC--GGTMRGSSGIISSP 215
Score = 45.4 bits (106), Expect = 3e-04
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPGE ++ R+ SD +G+T+Q++C+ +VL+G+ +TC W+ P C
Sbjct: 446 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
Score = 44.3 bits (103), Expect = 6e-04
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILG--QPSHWNGP 926
+S +C NPG+P G +LY + G+ + + C G+ L G + CI + W+ P
Sbjct: 134 QSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 191
Query: 927 LPVCK 931
+P+C+
Sbjct: 192 VPICR 196
Score = 40.0 bits (92), Expect = 0.011
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEES 870
VG I+Y+C G++L+G LTC + T W +P C +E++
Sbjct: 156 VGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 200
Score = 37.4 bits (85), Expect = 0.073
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHW 923
+ S C +PG PENG +I + G ++ F C E + L G +I C I + W
Sbjct: 439 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 496
Query: 924 NGPLPVCKV 932
+ PVCKV
Sbjct: 497 SDHRPVCKV 505
Score = 35.4 bits (80), Expect = 0.28
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLP 928
E +C +PG P Y I + + L F C GFEL+GE +I C + + W+ +P
Sbjct: 620 EKESCGDPGTPL--YGIREGDGFSNRDVLRFECQFGFELIGEKSIVC--QENNQWSANIP 675
Query: 929 VC 930
+C
Sbjct: 676 IC 677
Score = 33.5 bits (75), Expect = 1.1
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 894 GESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
G S+ F C G+ L G + IRC + + WN LP C V
Sbjct: 1857 GSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1897
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 233 bits (595), Expect = 5e-61
Identities = 167/515 (32%), Positives = 247/515 (47%), Gaps = 18/515 (3%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C S +N EG + S +YPL NN EC Y++ V G G+ + ++ +L+ G++L I
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1193
Query: 339 -GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFP 396
G D T + A + G + S +N + + F + + FQL Y +F LS C P
Sbjct: 1194 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1253
Query: 397 RRPDSG-DVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGA 455
P G ++ +G + C+ GY L G+ +L C+ + W P C A CGG
Sbjct: 1254 GIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1313
Query: 456 VHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTN 514
+ GR+LSP YP + + C+W IE G + L F D + V G
Sbjct: 1314 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1373
Query: 515 KSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQN 574
LL + + +P EG+ S N + I+F +D + S F I+F + C +P +
Sbjct: 1374 NDMLLKE-ISGSLIP-EGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
Query: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLCRAMCGGELS 633
N T + G V F CDPG+ L QG I CI V + Y W + P+C A CGG L+
Sbjct: 1432 -NGTRNGDGREPGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1489
Query: 634 AVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTIYDGDEVMPH 692
+G +LSPN+P PY DC W I V + I L I F N D L IYDG +
Sbjct: 1490 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1549
Query: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQ 752
++G + + P+++ SS+ + + F SD + GF + Y + +SC D I
Sbjct: 1550 LIGSFQDSKLPERIESSSNTMHLAFRSDGS----VSYTGFHLEY-KAKLRESCFDPGNIM 1604
Query: 753 NGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC 787
NG + +L G+ +TY CD GY + G TLTC
Sbjct: 1605 NGTRLGMDYKL--GSTVTYYCDAGYVLQGYSTLTC 1637
Score = 228 bits (580), Expect = 3e-59
Identities = 191/714 (26%), Positives = 306/714 (42%), Gaps = 87/714 (12%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGV 340
C + +G I S YP P +N L C + +TV G G+++QV S ++ S+
Sbjct: 1835 CGGILTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFY 1892
Query: 341 DG-----PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCN 394
DG P L + T+ ++ S +N + + F++ F L Y A L SC
Sbjct: 1893 DGGDNNAPRLGSYSGTTI---PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 1949
Query: 395 FPRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
P+ P SG + + D + G V F C GY LQG +TC+ W+ PIC A CG
Sbjct: 1950 EPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2008
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQ 512
GA+ + + G +LSP +P N S C WTI P G +HL F D + V SG
Sbjct: 2009 GAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2067
Query: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
+ S ++ L +P L S + + F SD ++ F+I ++A++ C +P
Sbjct: 2068 SETSTVI-GRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2125
Query: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+NG +D + +G + F C PG++L G + + C++ WN P C A+CGG
Sbjct: 2126 FRNGFVIGND--FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGN 2182
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN-SDILTIYDGDEVM 690
++A+ G + SP +P+ Y +DC W + V I+++ L D +T++DG +
Sbjct: 2183 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2242
Query: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
+GQ+ GN+ + +YS++ + I+FHSD F F+++Y + C P
Sbjct: 2243 SPQIGQFSGNTALESVYSTSNQILIKFHSD-----FTTSGFFVLSY-HAYQLRVCQPPPP 2296
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEKIMYCTD 808
+ N T E G I YQC PG+ +VG+ LTC+ L PP C+ + +
Sbjct: 2297 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2356
Query: 809 -----------PGEVDHSTRL--------------------------------------I 819
PG D L I
Sbjct: 2357 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI 2416
Query: 820 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP 879
PV L+ + Y+ G + +S + G R+ + + C P P
Sbjct: 2417 QSPV-LISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESP 2471
Query: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH--WNGPLPVCK 931
+GY I L + + C GF L+G+ + C + W+ P+P C+
Sbjct: 2472 PHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Score = 215 bits (547), Expect = 2e-55
Identities = 184/655 (28%), Positives = 286/655 (43%), Gaps = 45/655 (6%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNF---LECTYNVTVYTGYGVELQVKSVNLSDGEL- 334
A C + S+ G I S +P N+ L+CT+ + + G+GV LQ VN S +
Sbjct: 2005 AQCGGAMSDFSGVILSPGFP----GNYPSSLDCTWTINLPIGFGVHLQF--VNFSTETIH 2058
Query: 335 --LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML- 391
L +R T TV+ + + S T+ S+YF + F + YQA+ L
Sbjct: 2059 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
SC PR +G V D G F C GY L G LTC++ +W+ P C A
Sbjct: 2119 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2178
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHS 510
CGG + A G + SP YP+ Q C W + P G ++++F L D +TV
Sbjct: 2179 CGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2237
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
G S + + + E + S N I I+F SD + F + + A++ C P
Sbjct: 2238 GPDQNSPQIGQF--SGNTALESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPP 2294
Query: 571 Y-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC- 628
+ N T D + IG I+ + C PG +L G AI+ C + P+C+ +C
Sbjct: 2295 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCP 2353
Query: 629 GGELSAVA-GVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
EL + GV+LSP +P+ Y + C W I V + I + ++F D+L +YDG
Sbjct: 2354 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2413
Query: 687 DEVMPHILGQYLGN-SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
+ +L G+ S + S+ ++ +Q+ +D +GF + YI C
Sbjct: 2414 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN----NKKGFRIRYIAFY----C 2465
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL----SWSSDPPFCE 801
S +G+ S T + + + CD G+ +VG + C+ +W + P C+
Sbjct: 2466 STPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Query: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
I C P + L +D LVGT + Y CN G+ L L T + GT ++
Sbjct: 2525 AIS-CGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
Query: 862 LPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
P CV ++C P NG +I + Y G + F C GF L+G C+
Sbjct: 2582 TPRCV---VISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECL 2631
Score = 210 bits (535), Expect = 5e-54
Identities = 204/718 (28%), Positives = 307/718 (42%), Gaps = 88/718 (12%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
A C + + G+I S ++P P + +C + +TV Y + L S ++ + L I
Sbjct: 1482 APCGGNLTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1540
Query: 338 RGVDGPTLTVLANQTLLVEGQV------IRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
DGP +N L+ Q I S +NT+ + FR+ F L Y+A +
Sbjct: 1541 --YDGPD----SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1594
Query: 392 -SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASKPHWSSQEPIC 448
SC P +G MD G ++C GY LQG LTCI + +P W+ P C
Sbjct: 1595 ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1654
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
APCG + G VLSP+YP+N + C+++I P+ + F D + V
Sbjct: 1655 HAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEV 1713
Query: 509 HSGQTNKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
+ G T +S+LL S ES+P LS GN I I FTS A F+ ++A +
Sbjct: 1714 YDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPRT 1769
Query: 566 HCYE----PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WND 619
+ P + G ++ + +G+ V F C+PG+ L G I C V + WND
Sbjct: 1770 SSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWND 1826
Query: 620 TEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNS 678
+ P C CGG L+ G +LSP +PEPY +C+WKI V E I + + F N
Sbjct: 1827 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1886
Query: 679 DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
D L YDG + LG Y G + P L S++ +L + F SD I GF + Y
Sbjct: 1887 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD----ISVSAAGFHLEYTA 1942
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ DSC + +G K + G +++QCD GY + G +TC W+
Sbjct: 1943 IGL-DSCPEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 1999
Query: 797 PPFC------------EKIMYCTDPGEVDHS---TRLISDPVLLVGTTIQYTCNPGFVLE 841
P C I+ PG S T I+ P+ G +Q+ +
Sbjct: 2000 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF-GVHLQFVNFSTETIH 2058
Query: 842 GSSLLTCYSRETGT-------PIWTSRLPHCVSEESLACDNP-GLPENGYQILYKRLYLP 893
+ S ET T P S L E SL + + G+ I+Y+ L
Sbjct: 2059 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2118
Query: 894 --------------------GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
G++++F C+ G+ L+G + C+ G +WN PLP C+
Sbjct: 2119 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2176
Score = 203 bits (517), Expect = 6e-52
Identities = 158/526 (30%), Positives = 246/526 (46%), Gaps = 29/526 (5%)
Query: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPT----L 345
G I S YP P +N L C + + V G V LQ + + + +R DGP L
Sbjct: 1320 GRILSPGYPF-PYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDI-LRVWDGPPENDML 1377
Query: 346 TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFPRRPDSGDV 404
+ +L+ EG I S N +++ F T F + + + + + C P P +G
Sbjct: 1378 LKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTR 1435
Query: 405 TVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGR 463
G F C GYELQG + +TCI + W P+C APCGG + ++ G
Sbjct: 1436 NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSS-GF 1494
Query: 464 VLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDS 522
+LSP++P S+ C WTI + L F + D + ++ G + S L+ S
Sbjct: 1495 ILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLI-GS 1553
Query: 523 LQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSD 581
Q +P E + S NT+ + F SD + + + F++ ++A + C++P I NG D
Sbjct: 1554 FQDSKLP-ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD 1612
Query: 582 PTYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVV 639
Y +G+ V + CD G+ L QG + + CI D P WN P C A CG + G V
Sbjct: 1613 --YKLGSTVTYYCDAGYVL-QGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1669
Query: 640 LSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG 699
LSPN+P+ Y G +C++ I V +E +F F S D++ +YDG +L G
Sbjct: 1670 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1729
Query: 700 -NSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT 758
+SG SS +TI+F S G I KG F+ + + + CS +PE + G +
Sbjct: 1730 SHSGESLPLSSGNQITIRFTS--VGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG 1787
Query: 759 SHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFC 800
+ E G+ + + C+PGY + GS + C+ W+ P C
Sbjct: 1788 N--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1831
Score = 201 bits (511), Expect = 3e-51
Identities = 203/744 (27%), Positives = 310/744 (41%), Gaps = 87/744 (11%)
Query: 252 GSASEESQETTTSTIITTTVITTEQAP---ALCSVSFSNPEGYIDSSDYPLLPLNNFLEC 308
G + ET T ++ V+ + P A C FS P G I S +P + L C
Sbjct: 759 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY-YKDSLNC 817
Query: 309 TYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTN 365
+ + G+ +++ + + ++L + DGP L +L + Q + S +N
Sbjct: 818 EWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLLGSYNGTQVPQFLFSSSN 875
Query: 366 TISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLG 422
I + F T F++HY++ + SC P P G D G F C G
Sbjct: 876 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 935
Query: 423 YELQGAKMLTCINASKPHWSSQE-PICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIW 481
Y L + L C K HW S P C A CGG V + G +LSP YPE S C W
Sbjct: 936 YRLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPS-GTILSPGYPEFYPNSLNCTW 991
Query: 482 TIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
T++ G+ + +F L HD +T + T A L S ++ GL
Sbjct: 992 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTIN-AGLYGNFR 1050
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
++ F SD + + FNI F + C +P I Q G+ + + IG + F+C G
Sbjct: 1051 A-QLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN--FGIGDTLTFSCSSG 1107
Query: 598 HSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWK 657
+ LE G + I C+ W+ P C A CG + G++LSPN+P Y +CI+
Sbjct: 1108 YRLE-GTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYS 1166
Query: 658 IHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPD-LTIQ 716
I V K I + + +L+ D+L IYDG + H+LG + G S SST + L ++
Sbjct: 1167 IQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLE 1226
Query: 717 FHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
F+SD G +GF + Y + C D Q G+K + G+ I Y C+PG
Sbjct: 1227 FNSDTE----GTDEGFQLVYTSFELS-HCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPG 1280
Query: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS---------------- 820
Y + GS L C + D P I C + + S R++S
Sbjct: 1281 YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWM 1340
Query: 821 ---DPVLLVGTTIQYTC--------------------------NPGFVLEG-SSLLTCYS 850
DP +V ++Q+ + + EG S L +
Sbjct: 1341 IEVDPGNIV--SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVT 1398
Query: 851 RETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFEL 907
+ T + S+ + S + AC +PG+P NG + R PG+++ F C G+EL
Sbjct: 1399 IQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYEL 1456
Query: 908 MGEVTIRCILGQPSH-WNGPLPVC 930
GE I CI + + W PVC
Sbjct: 1457 QGEERITCIQVENRYFWQPSPPVC 1480
Score = 170 bits (431), Expect = 6e-42
Identities = 183/719 (25%), Positives = 297/719 (41%), Gaps = 98/719 (13%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSIRG 339
C +F+ P G + S DYP NN L C + + G + L +L S + L+++
Sbjct: 617 CLSNFTAPMGTVLSPDYPEGYGNN-LNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 675
Query: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
D P +L T + S ++ + + F+ F + Y F C P
Sbjct: 676 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 735
Query: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
P + + G C G+ + QG + +TCI K WS P C APCGG
Sbjct: 736 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH- 794
Query: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
+A G +LSP +P S C W IEA G + + FER + D + VH G
Sbjct: 795 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 854
Query: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG--HCYEPYIQ 573
S LL S VP + L S N I + FT+D +R+ + F I +E+ C +P I
Sbjct: 855 SPLL-GSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 912
Query: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+G D ++IG+ V F+CD G+ L + P + E ++ +W+ P C A+CGG+
Sbjct: 913 VHGRRYGHD--FSIGSTVSFSCDSGYRLSHEEPLLCE----KNHWWSHPLPTCDALCGGD 966
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYD----- 685
+ +G +LSP +PE Y +C W + V K + + +L + D L I +
Sbjct: 967 VRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT 1026
Query: 686 -------GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
G ++ P I GN Q + S D +I + +GF + + E
Sbjct: 1027 QPLARLTGSDLPPTINAGLYGNFRAQLRFIS--DFSISY------------EGFNITFSE 1072
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ + C D Q G + + + G +T+ C GY + G+ + C WS+
Sbjct: 1073 YNL-EPCEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAP 1129
Query: 797 PPFC-----------EKIMYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCN-----PGFV 839
P C E I+ + P +++ I + G I + G V
Sbjct: 1130 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV 1189
Query: 840 LE----------------GSSLLTCYSRETGTPIWTS------------RLPHCVSEESL 871
L+ G+S+ T +W +L + S E
Sbjct: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY-TSFELS 1248
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
C++PG+P+ GY+I + + G ++ + C G+ L G ++C+ G+ W+ PLP C
Sbjct: 1249 HCEDPGIPQFGYKI-SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1306
Score = 134 bits (338), Expect = 3e-31
Identities = 140/569 (24%), Positives = 225/569 (39%), Gaps = 61/569 (10%)
Query: 276 QAPALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-EL 334
+A C + G I S +P NN +CT+ + G + L + + +
Sbjct: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNN-ADCTWTIVAEPGDTISLIFTDFQMEEKYDY 294
Query: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQA------ 388
L I G + PT+ + + + +I S N + ++F T + F YQ
Sbjct: 295 LEIEGSEPPTIWLSG---MNIPPPII-SNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
Query: 389 ----FMLS-----------------------CNFPRRPDSGDVTVMDLHSGGVAHFHCHL 421
F L C P P++G D G F C
Sbjct: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDE 410
Query: 422 GYELQGAKMLTCINASKPH--WSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
Y LQGAK +TC ++ WS P+C G+ G SP++P + + C
Sbjct: 411 DYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQC 470
Query: 480 IWTIEAPEGQK-LHLHFERLLLH-DKDRMTV-HSGQTNKSALLYDSLQTESVPFEGLLSE 536
+W I A K + ++FE L D +T+ G+ + L VP + ++S
Sbjct: 471 VWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-DLIVSM 529
Query: 537 GNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDP 596
+ + + +D++ + F + ++ EK C +P D N ++ F C
Sbjct: 530 SSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSN-RDVLRFECQF 588
Query: 597 GHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIW 656
G L G I C + W+ P+C C +A G VLSP++PE Y +CIW
Sbjct: 589 GFELI-GEKSIVC--QENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIW 645
Query: 657 KIHVGEEKRIFLDIQFLNL-SNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTI 715
I RI L +L S D L + DGD ILG + G P L S++ L +
Sbjct: 646 TIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRL 705
Query: 716 QFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDP 775
+F +D + G+GF + Y N+ C D N + + +L G+ I+ C+
Sbjct: 706 EFQADHS----MSGRGFNITYNTFGHNE-CPDPGIPINARRFGDNFQL--GSSISVICEE 758
Query: 776 GY-DIVGSDTLTC---QWDLSWSSDPPFC 800
G+ G++T+TC + WS P C
Sbjct: 759 GFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 132 bits (332), Expect = 2e-30
Identities = 127/470 (27%), Positives = 208/470 (44%), Gaps = 73/470 (15%)
Query: 382 FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASK 438
F+++Y+ S C P P G + G + C GY L G LTCI + +
Sbjct: 166 FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNT 225
Query: 439 PHWSSQEPICSA--PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
W PIC A CGG + ++ G + SPS+P + + C WTI A G + L F
Sbjct: 226 ASWDFPVPICRAEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFT 284
Query: 497 RLLLHDK-DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSD-------- 547
+ +K D + + + L ++P ++S N +R+ F +D
Sbjct: 285 DFQMEEKYDYLEIEGSEPPTI-----WLSGMNIP-PPIISNKNWLRLHFVTDSNHRYRGF 338
Query: 548 ----QARAASTFNIR-------------FEAFEKGH-------CYEP-YIQNGNFTTSDP 582
Q + A F R F +G C +P +NG SD
Sbjct: 339 SAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSD- 397
Query: 583 TYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLCRA-MCGGELSAVAGVV 639
+++G+ V+F+CD + L QG I C + + + W+D P+C+ CG L +G
Sbjct: 398 -FSLGSTVQFSCDEDYVL-QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTF 455
Query: 640 LSPNWPEPYVEGEDCIWKI-HVGEEKRIFLDIQFLNLS-NSDILTIYDGDEV-MPHILGQ 696
SPN+P Y C+W I V K I ++ + +L D LTI DG EV P + Q
Sbjct: 456 TSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQ 515
Query: 697 YL-GNSGPQKLYSSTPDLTIQFHSDPA-GLIFGKGQGFIMNYIEVSRNDSCSD----LPE 750
L G+ P + S + + + +D + G + GF +NY E+ + +SC D L
Sbjct: 516 VLTGSFVPDLIVSMSSQMWLHLQTDESVGSV-----GFKVNYKEIEK-ESCGDPGTPLYG 569
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
I+ G S+ +++R ++C G++++G ++ CQ + WS++ P C
Sbjct: 570 IREG-DGFSNRDVLR-----FECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 100 bits (248), Expect = 9e-21
Identities = 97/397 (24%), Positives = 166/397 (41%), Gaps = 59/397 (14%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHS 510
CGG + G + SP +P C W I A E ++ + F+ L ++ D ++++
Sbjct: 65 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD 123
Query: 511 GQTNKSALLYDSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G + + + +T F + S + + TSD A +A F + +E + C
Sbjct: 124 GHPHPT-----NFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCR 625
P + +++G + ++C G+ L+ P + CI +V W+ P+CR
Sbjct: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLT-CIANSVNTASWDFPVPICR 236
Query: 626 A--MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE----KRIFLDIQ------FL 673
A CGG + +G++ SP++P Y DC W I V E IF D Q +L
Sbjct: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI-VAEPGDTISLIFTDFQMEEKYDYL 295
Query: 674 NLSNSDILTIY-DGDEVMPHILG---------------QYLGNSGPQKLYSSTPDLTIQF 717
+ S+ TI+ G + P I+ +Y G S P ++ + I F
Sbjct: 296 EIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKA-----IDF 350
Query: 718 HSDPAGLIFGKGQGFIMNYIE----VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQC 773
S L GK + + + ++ C D E +NG + S L G+ + + C
Sbjct: 351 KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSC 408
Query: 774 DPGYDIVGSDTLTCQ----WDLSWSSDPPFCEKIMYC 806
D Y + G+ ++TCQ +WS P C K+ C
Sbjct: 409 DEDYVLQGAKSITCQRIAEVFAAWSDHRPVC-KVKTC 444
Score = 93.6 bits (231), Expect = 9e-19
Identities = 133/594 (22%), Positives = 216/594 (36%), Gaps = 72/594 (12%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+SC P P G + + V F C++GY +QG C + WS P+C
Sbjct: 2704 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMCKV 2761
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
V+ + G + F T+ + + F +L + +
Sbjct: 2762 -----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL-----ICQPN 2811
Query: 511 GQTNK---SALLYDSLQTESVPFEGLLSE----GNTIRIEFTSD-----QARAASTFNIR 558
GQ +K ++ D P L E G+T+ T Q+ N
Sbjct: 2812 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
Query: 559 FEAFEK-------GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECIN 611
+ + G C +P G+ + + + + V + CD G+ L G C+
Sbjct: 2872 WSGSQPHCSGDATGTCGDPGTP-GHGSRQESNFRTKSTVRYACDTGYILH-GSEERTCL- 2928
Query: 612 VRDPYWNDTEPLCRAM-CG-------GELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
+ W +P C+A+ CG G++ + G S + +EG I G
Sbjct: 2929 -ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGY-----ILSGPS 2982
Query: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSD 720
R + + + I GD +P G G+ G Y P T++ +
Sbjct: 2983 VRQCTANGTWSGTLPNCTIISCGDPGIP-ANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3041
Query: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
G + R +C P+I NG T G I+Y C PGY++
Sbjct: 3042 RIRTCTINGTW--SGVMPTCRAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELS 3097
Query: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
LTC + +WS + P C +C DPG R + + + ++CN F+L
Sbjct: 3098 FPAVLTCVGNGTWSGEVPQCLP-KFCGDPGIPAQGKR--EGKSFIYQSEVSFSCNFPFIL 3154
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
GSS C + T W+ PHC+ +C+NPG+P +G Q + G + F
Sbjct: 3155 VGSSTRICQADGT----WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFH 3209
Query: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEG 954
C +G L G T C+ W+G P C H+ + E A ++ G
Sbjct: 3210 CKKGHLLQGSTTRTCL--PDLTWSGIQPEC------IPHSCKQPETPAHANVVG 3255
Score = 82.0 bits (201), Expect = 3e-15
Identities = 133/599 (22%), Positives = 226/599 (37%), Gaps = 103/599 (17%)
Query: 380 GTFQLHYQA---FMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINA 436
GT+ H + ++SC P +G+ G A F C LG+ L G+ + C+++
Sbjct: 2574 GTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2633
Query: 437 SKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTN------------GSQFCI---- 480
WS E C A G G+V+ +Y GS I
Sbjct: 2634 GL--WSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQD 2691
Query: 481 --WTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
W+ + P + ++ G+T+ + ++ + T S G L +G
Sbjct: 2692 HNWSGQLPSCVPVSCGHPGSPIY---------GRTSGNGFNFNDVVTFSCNI-GYLMQGP 2741
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI----------QNGNFTTSDPTYNIGT 588
T Q +A ++ + +C +P I ++GNFT GT
Sbjct: 2742 ------TKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFT-------YGT 2788
Query: 589 IVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPY 648
+V + C+PG+ L G +++ C + W+ P C + G VLS E Y
Sbjct: 2789 VVFYDCNPGYFL-FGSSVLIC--QPNGQWDKPLPECIMIDCGHPGVPPNAVLS---GEKY 2842
Query: 649 VEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG--------N 700
G + G+ + + L+ + G + PH G G
Sbjct: 2843 TFGSTVHYSC-TGKRSLLGQSSRTCQLNGH-----WSGSQ--PHCSGDATGTCGDPGTPG 2894
Query: 701 SGPQKLYSSTPDLTIQFHSDPAGLIFG-KGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTS 759
G ++ + T+++ D ++ G + + + N R C + G TT+
Sbjct: 2895 HGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG--TTA 2952
Query: 760 HTELVR------GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVD 813
+ ++ R + + Y C GY + G C + +WS P C I+ C DPG
Sbjct: 2953 NGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIISCGDPGIPA 3011
Query: 814 HSTRLISDPVLLVGTTIQYTCNPGFVLE--GSSLLTCYSRETGTPIWTSRLPHCVSEESL 871
+ R D V VG + Y C PG+ +E GS + TC T W+ +P C ++
Sbjct: 3012 NGLRYGDDYV--VGQNVSYMCQPGYTMELNGSRIRTCTINGT----WSGVMPTC---RAV 3062
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
C P NG L + G S++++C G+EL + C+ W+G +P C
Sbjct: 3063 TCPTPPQISNGR--LEGTNFDWGFSISYICSPGYELSFPAVLTCV--GNGTWSGEVPQC 3117
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/532 (21%), Positives = 189/532 (35%), Gaps = 85/532 (15%)
Query: 387 QAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEP 446
+ M+ C P P + ++ G H+ C L G TC HWS +P
Sbjct: 2820 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTC--QLNGHWSGSQP 2877
Query: 447 ICSAPCGGAVHN-----------------ATIGRVLSPSYPENTNGSQFCI----WTIEA 485
CS G + +T+ Y + + + C+ WT
Sbjct: 2878 HCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQ 2937
Query: 486 PEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFT 545
PE + + + K + G T S+++Y + EG + G ++R
Sbjct: 2938 PECKAVQCGNPGTTANGK--VFRIDGTTFSSSVIYSCM-------EGYILSGPSVR---- 2984
Query: 546 SDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPA 605
Q A T++ C +P I D Y +G V + C PG+++E +
Sbjct: 2985 --QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVVGQNVSYMCQPGYTMELNGS 3041
Query: 606 IIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKR 665
I + W+ P CRA+ P +EG + W +
Sbjct: 3042 RIRTCTINGT-WSGVMPTCRAVT---------CPTPPQISNGRLEGTNFDWGFSIS---- 3087
Query: 666 IFLDIQFLNLSNSDILTI-----YDGDEVMPHILGQYLGN---------SGPQKLYSSTP 711
++ LS +LT + G+ +P L ++ G+ G +Y S
Sbjct: 3088 -YICSPGYELSFPAVLTCVGNGTWSGE--VPQCLPKFCGDPGIPAQGKREGKSFIYQSEV 3144
Query: 712 DLTIQFHSDPAGLIF------GKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR 765
+ F G G G + IE ++ SC + ++G + + V
Sbjct: 3145 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT-SCENPGVPRHGSQNNTFGFQV- 3202
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G+ + + C G+ + GS T TC DL+WS P C I + E ++ +
Sbjct: 3203 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC--IPHSCKQPETPAHANVVGMDLPS 3260
Query: 826 VGTTIQYTCNPGFVLE-GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
G T+ YTC PGF L G+ C S T WT ++P C + + +P
Sbjct: 3261 HGYTLIYTCQPGFFLAGGTEHRVCRSDNT----WTGKVPICEAGSKILVKDP 3308
Score = 73.6 bits (179), Expect = 9e-13
Identities = 64/219 (29%), Positives = 95/219 (43%), Gaps = 30/219 (13%)
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
SC +LP NG K + T G+ + CD G+ +VGS C WS C
Sbjct: 2589 SCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC-LA 2645
Query: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
+C P E+ + ++I + T + Y CNPGF L GSS+ C W+ +LP
Sbjct: 2646 GHCGIP-ELIVNGQVIGENYGYRDTVV-YQCNPGFRLIGSSVRICQQDHN----WSGQLP 2699
Query: 864 HCVSEESLACDNPGLP------ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL 917
CV ++C +PG P NG+ + +TF C G+ + G +C
Sbjct: 2700 SCV---PVSCGHPGSPIYGRTSGNGFNF--------NDVVTFSCNIGYLMQGPTKAQCQA 2748
Query: 918 GQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGN 956
+ W+ P P+CKV S A + E+ +E GN
Sbjct: 2749 NR--QWSHPPPMCKVVNCSDPGI--PANSKRESKIEHGN 2783
Score = 62.4 bits (150), Expect = 2e-09
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 14/200 (7%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
CGG L + G + SP +P Y G +C W I E RI + Q L D L++YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
+ + G P + S+ +++ SD A GF + Y E+ ++ SC
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA----VSAHGFKVYYEEL-QSSSCG 179
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEK 802
+ G T G +I Y C GY + G LTC + SW P C
Sbjct: 180 NPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
Query: 803 IMYCTDPGEVDHSTRLISDP 822
C G + S+ +IS P
Sbjct: 238 EDAC--GGTMRGSSGIISSP 255
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/141 (24%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 791 LSWSSDPPFCEK-------IMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGS 843
L WS+D +K YC+ P H +IS + + +++ C+ GF L G
Sbjct: 2443 LQWSADHGNNKKGFRIRYIAFYCSTPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGK 2501
Query: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYE 903
S C G W + +P C ++++C P P NG + YL G +T+ C +
Sbjct: 2502 SSAVCRKSSYGYHAWDAPVPAC---QAISCGIPKAPTNGGILTTD--YLVGTRVTYFCND 2556
Query: 904 GFELMGEVTIRCILGQPSHWN 924
G+ L + + W+
Sbjct: 2557 GYRLSSKELTTAVCQSDGTWS 2577
Score = 44.3 bits (103), Expect = 6e-04
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILG--QPSHWNGP 926
+S +C NPG+P G +LY + G+ + + C G+ L G + CI + W+ P
Sbjct: 174 QSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 231
Query: 927 LPVCK 931
+P+C+
Sbjct: 232 VPICR 236
Score = 40.0 bits (92), Expect = 0.011
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEES 870
VG I+Y+C G++L+G LTC + T W +P C +E++
Sbjct: 196 VGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Score = 37.4 bits (85), Expect = 0.073
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHW 923
+ S C +PG PENG +I + G ++ F C E + L G +I C I + W
Sbjct: 375 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 432
Query: 924 NGPLPVCKV 932
+ PVCKV
Sbjct: 433 SDHRPVCKV 441
Score = 35.4 bits (80), Expect = 0.28
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLP 928
E +C +PG P Y I + + L F C GFEL+GE +I C + + W+ +P
Sbjct: 556 EKESCGDPGTPL--YGIREGDGFSNRDVLRFECQFGFELIGEKSIVC--QENNQWSANIP 611
Query: 929 VC 930
+C
Sbjct: 612 IC 613
Score = 35.4 bits (80), Expect = 0.28
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 894 GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
G+ + + C GF L+G + C LG+ +G PVC+V
Sbjct: 2312 GDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2350
Score = 33.5 bits (75), Expect = 1.1
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 894 GESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
G S+ F C G+ L G + IRC + + WN LP C V
Sbjct: 1793 GSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1833
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 233 bits (595), Expect = 5e-61
Identities = 167/515 (32%), Positives = 247/515 (47%), Gaps = 18/515 (3%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIR 338
A C S +N EG + S +YPL NN EC Y++ V G G+ + ++ +L+ G++L I
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHLAQGDVLKIY 1297
Query: 339 -GVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFP 396
G D T + A + G + S +N + + F + + FQL Y +F LS C P
Sbjct: 1298 DGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDP 1357
Query: 397 RRPDSG-DVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGA 455
P G ++ +G + C+ GY L G+ +L C+ + W P C A CGG
Sbjct: 1358 GIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGR 1417
Query: 456 VHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTN 514
+ GR+LSP YP + + C+W IE G + L F D + V G
Sbjct: 1418 FKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPE 1477
Query: 515 KSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQN 574
LL + + +P EG+ S N + I+F +D + S F I+F + C +P +
Sbjct: 1478 NDMLLKE-ISGSLIP-EGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1535
Query: 575 GNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLCRAMCGGELS 633
N T + G V F CDPG+ L QG I CI V + Y W + P+C A CGG L+
Sbjct: 1536 -NGTRNGDGREPGDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLT 1593
Query: 634 AVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNSDILTIYDGDEVMPH 692
+G +LSPN+P PY DC W I V + I L I F N D L IYDG +
Sbjct: 1594 GSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSP 1653
Query: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQ 752
++G + + P+++ SS+ + + F SD + GF + Y + +SC D I
Sbjct: 1654 LIGSFQDSKLPERIESSSNTMHLAFRSDGS----VSYTGFHLEY-KAKLRESCFDPGNIM 1708
Query: 753 NGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC 787
NG + +L G+ +TY CD GY + G TLTC
Sbjct: 1709 NGTRLGMDYKL--GSTVTYYCDAGYVLQGYSTLTC 1741
Score = 228 bits (580), Expect = 3e-59
Identities = 191/714 (26%), Positives = 306/714 (42%), Gaps = 87/714 (12%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGV 340
C + +G I S YP P +N L C + +TV G G+++QV S ++ S+
Sbjct: 1939 CGGILTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSF-ATEHNWDSLDFY 1996
Query: 341 DG-----PTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML-SCN 394
DG P L + T+ ++ S +N + + F++ F L Y A L SC
Sbjct: 1997 DGGDNNAPRLGSYSGTTI---PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 2053
Query: 395 FPRRPDSGDVTVMDLHS-GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
P+ P SG + + D + G V F C GY LQG +TC+ W+ PIC A CG
Sbjct: 2054 EPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCG 2112
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHSGQ 512
GA+ + + G +LSP +P N S C WTI P G +HL F D + V SG
Sbjct: 2113 GAMSDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2171
Query: 513 TNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPY- 571
+ S ++ L +P L S + + F SD ++ F+I ++A++ C +P
Sbjct: 2172 SETSTVI-GRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRP 2229
Query: 572 IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+NG +D + +G + F C PG++L G + + C++ WN P C A+CGG
Sbjct: 2230 FRNGFVIGND--FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGN 2286
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN-SDILTIYDGDEVM 690
++A+ G + SP +P+ Y +DC W + V I+++ L D +T++DG +
Sbjct: 2287 ITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQN 2346
Query: 691 PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPE 750
+GQ+ GN+ + +YS++ + I+FHSD F F+++Y + C P
Sbjct: 2347 SPQIGQFSGNTALESVYSTSNQILIKFHSD-----FTTSGFFVLSY-HAYQLRVCQPPPP 2400
Query: 751 IQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSDPPFCEKIMYCTD 808
+ N T E G I YQC PG+ +VG+ LTC+ L PP C+ + +
Sbjct: 2401 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 2460
Query: 809 -----------PGEVDHSTRL--------------------------------------I 819
PG D L I
Sbjct: 2461 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNI 2520
Query: 820 SDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP 879
PV L+ + Y+ G + +S + G R+ + + C P P
Sbjct: 2521 QSPV-LISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESP 2575
Query: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH--WNGPLPVCK 931
+GY I L + + C GF L+G+ + C + W+ P+P C+
Sbjct: 2576 PHGYIISQTGGQL-NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Score = 216 bits (549), Expect = 1e-55
Identities = 182/671 (27%), Positives = 290/671 (43%), Gaps = 40/671 (5%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNF---LECTYNVTVYTGYGVELQVKSVNLSDGEL- 334
A C + S+ G I S +P N+ L+CT+ + + G+GV LQ VN S +
Sbjct: 2109 AQCGGAMSDFSGVILSPGFP----GNYPSSLDCTWTINLPIGFGVHLQF--VNFSTETIH 2162
Query: 335 --LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML- 391
L +R T TV+ + + S T+ S+YF + F + YQA+ L
Sbjct: 2163 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2222
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
SC PR +G V D G F C GY L G LTC++ +W+ P C A
Sbjct: 2223 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL 2282
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHD-KDRMTVHS 510
CGG + A G + SP YP+ Q C W + P G ++++F L D +TV
Sbjct: 2283 CGGNI-TAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWD 2341
Query: 511 GQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP 570
G S + + + E + S N I I+F SD + F + + A++ C P
Sbjct: 2342 GPDQNSPQIGQF--SGNTALESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPP 2398
Query: 571 Y-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC- 628
+ N T D + IG I+ + C PG +L G AI+ C + P+C+ +C
Sbjct: 2399 PPVPNAEILTEDDEFEIGDIIRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCP 2457
Query: 629 GGELSAVA-GVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
EL + GV+LSP +P+ Y + C W I V + I + ++F D+L +YDG
Sbjct: 2458 ANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDG 2517
Query: 687 DEVMPHILGQYLGN-SGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSC 745
+ +L G+ S + S+ ++ +Q+ +D +GF + YI C
Sbjct: 2518 PNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN----NKKGFRIRYIAFY----C 2569
Query: 746 SDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDL----SWSSDPPFCE 801
S +G+ S T + + + CD G+ +VG + C+ +W + P C+
Sbjct: 2570 STPESPPHGY-IISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
I C P + L +D LVGT + Y CN G+ L L T + GT ++
Sbjct: 2629 AIS-CGIPKAPTNGGILTTD--YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2685
Query: 862 LPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS 921
P CV + ++ L ++I+ Y + F C G+ +G +I C+
Sbjct: 2686 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTW 2745
Query: 922 HWNGPLPVCKV 932
W P C++
Sbjct: 2746 SWRNERPYCQI 2756
Score = 210 bits (535), Expect = 5e-54
Identities = 204/718 (28%), Positives = 307/718 (42%), Gaps = 88/718 (12%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG-ELLSI 337
A C + + G+I S ++P P + +C + +TV Y + L S ++ + L I
Sbjct: 1586 APCGGNLTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYI 1644
Query: 338 RGVDGPTLTVLANQTLLVEGQV------IRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
DGP +N L+ Q I S +NT+ + FR+ F L Y+A +
Sbjct: 1645 --YDGPD----SNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLR 1698
Query: 392 -SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASKPHWSSQEPIC 448
SC P +G MD G ++C GY LQG LTCI + +P W+ P C
Sbjct: 1699 ESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Query: 449 SAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTV 508
APCG + G VLSP+YP+N + C+++I P+ + F D + V
Sbjct: 1759 HAPCGSR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEV 1817
Query: 509 HSGQTNKSALLYD---SLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
+ G T +S+LL S ES+P LS GN I I FTS A F+ ++A +
Sbjct: 1818 YDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPRT 1873
Query: 566 HCYE----PYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WND 619
+ P + G ++ + +G+ V F C+PG+ L G I C V + WND
Sbjct: 1874 SSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWND 1930
Query: 620 TEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLD-IQFLNLSNS 678
+ P C CGG L+ G +LSP +PEPY +C+WKI V E I + + F N
Sbjct: 1931 SLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNW 1990
Query: 679 DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
D L YDG + LG Y G + P L S++ +L + F SD I GF + Y
Sbjct: 1991 DSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSD----ISVSAAGFHLEYTA 2046
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ DSC + +G K + G +++QCD GY + G +TC W+
Sbjct: 2047 IGL-DSCPEPQTPSSGIKIGD--RYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYP 2103
Query: 797 PPFC------------EKIMYCTDPGEVDHS---TRLISDPVLLVGTTIQYTCNPGFVLE 841
P C I+ PG S T I+ P+ G +Q+ +
Sbjct: 2104 IPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF-GVHLQFVNFSTETIH 2162
Query: 842 GSSLLTCYSRETGT-------PIWTSRLPHCVSEESLACDNP-GLPENGYQILYKRLYLP 893
+ S ET T P S L E SL + + G+ I+Y+ L
Sbjct: 2163 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ 2222
Query: 894 --------------------GESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
G++++F C+ G+ L+G + C+ G +WN PLP C+
Sbjct: 2223 SCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Score = 203 bits (517), Expect = 6e-52
Identities = 158/526 (30%), Positives = 246/526 (46%), Gaps = 29/526 (5%)
Query: 290 GYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPT----L 345
G I S YP P +N L C + + V G V LQ + + + +R DGP L
Sbjct: 1424 GRILSPGYPF-PYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDI-LRVWDGPPENDML 1481
Query: 346 TVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLS-CNFPRRPDSGDV 404
+ +L+ EG I S N +++ F T F + + + + + C P P +G
Sbjct: 1482 LKEISGSLIPEG--IHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTR 1539
Query: 405 TVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH-WSSQEPICSAPCGGAVHNATIGR 463
G F C GYELQG + +TCI + W P+C APCGG + ++ G
Sbjct: 1540 NGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSS-GF 1598
Query: 464 VLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHSGQTNKSALLYDS 522
+LSP++P S+ C WTI + L F + D + ++ G + S L+ S
Sbjct: 1599 ILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLI-GS 1657
Query: 523 LQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSD 581
Q +P E + S NT+ + F SD + + + F++ ++A + C++P I NG D
Sbjct: 1658 FQDSKLP-ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD 1716
Query: 582 PTYNIGTIVEFTCDPGHSLEQGPAIIECINVRD--PYWNDTEPLCRAMCGGELSAVAGVV 639
Y +G+ V + CD G+ L QG + + CI D P WN P C A CG + G V
Sbjct: 1717 --YKLGSTVTYYCDAGYVL-QGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTV 1773
Query: 640 LSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLG 699
LSPN+P+ Y G +C++ I V +E +F F S D++ +YDG +L G
Sbjct: 1774 LSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSG 1833
Query: 700 -NSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT 758
+SG SS +TI+F S G I KG F+ + + + CS +PE + G +
Sbjct: 1834 SHSGESLPLSSGNQITIRFTS--VGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIG 1891
Query: 759 SHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFC 800
+ E G+ + + C+PGY + GS + C+ W+ P C
Sbjct: 1892 N--EFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC 1935
Score = 201 bits (511), Expect = 3e-51
Identities = 203/744 (27%), Positives = 310/744 (41%), Gaps = 87/744 (11%)
Query: 252 GSASEESQETTTSTIITTTVITTEQAP---ALCSVSFSNPEGYIDSSDYPLLPLNNFLEC 308
G + ET T ++ V+ + P A C FS P G I S +P + L C
Sbjct: 863 GFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY-YKDSLNC 921
Query: 309 TYNVTVYTGYGVELQVKSVNLS-DGELLSIRGVDGPTLT--VLANQTLLVEGQVIRSPTN 365
+ + G+ +++ + + ++L + DGP L +L + Q + S +N
Sbjct: 922 EWVIEAEPGHSIKITFERFQTELNYDVLEVH--DGPNLLSPLLGSYNGTQVPQFLFSSSN 979
Query: 366 TISVYFRTFQDDGLGTFQLHYQAFML---SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLG 422
I + F T F++HY++ + SC P P G D G F C G
Sbjct: 980 FIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSG 1039
Query: 423 YELQGAKMLTCINASKPHWSSQE-PICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIW 481
Y L + L C K HW S P C A CGG V + G +LSP YPE S C W
Sbjct: 1040 YRLSHEEPLLC---EKNHWWSHPLPTCDALCGGDVRGPS-GTILSPGYPEFYPNSLNCTW 1095
Query: 482 TIEAPEGQKLHLHFERLLL---HDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
T++ G+ + +F L HD +T + T A L S ++ GL
Sbjct: 1096 TVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTIN-AGLYGNFR 1154
Query: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYI-QNGNFTTSDPTYNIGTIVEFTCDPG 597
++ F SD + + FNI F + C +P I Q G+ + + IG + F+C G
Sbjct: 1155 A-QLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFN--FGIGDTLTFSCSSG 1211
Query: 598 HSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWK 657
+ LE G + I C+ W+ P C A CG + G++LSPN+P Y +CI+
Sbjct: 1212 YRLE-GTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYS 1270
Query: 658 IHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPD-LTIQ 716
I V K I + + +L+ D+L IYDG + H+LG + G S SST + L ++
Sbjct: 1271 IQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLE 1330
Query: 717 FHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPG 776
F+SD G +GF + Y + C D Q G+K + G+ I Y C+PG
Sbjct: 1331 FNSDTE----GTDEGFQLVYTSFELS-HCEDPGIPQFGYKISDQGHFA-GSTIIYGCNPG 1384
Query: 777 YDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS---------------- 820
Y + GS L C + D P I C + + S R++S
Sbjct: 1385 YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWM 1444
Query: 821 ---DPVLLVGTTIQYTC--------------------------NPGFVLEG-SSLLTCYS 850
DP +V ++Q+ + + EG S L +
Sbjct: 1445 IEVDPGNIV--SLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVT 1502
Query: 851 RETGTPIWTSRLPHCV---SEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFEL 907
+ T + S+ + S + AC +PG+P NG + R PG+++ F C G+EL
Sbjct: 1503 IQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGR--EPGDTVVFQCDPGYEL 1560
Query: 908 MGEVTIRCILGQPSH-WNGPLPVC 930
GE I CI + + W PVC
Sbjct: 1561 QGEERITCIQVENRYFWQPSPPVC 1584
Score = 170 bits (431), Expect = 6e-42
Identities = 183/719 (25%), Positives = 297/719 (41%), Gaps = 98/719 (13%)
Query: 281 CSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNL-SDGELLSIRG 339
C +F+ P G + S DYP NN L C + + G + L +L S + L+++
Sbjct: 721 CLSNFTAPMGTVLSPDYPEGYGNN-LNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKD 779
Query: 340 VDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAF-MLSCNFPRR 398
D P +L T + S ++ + + F+ F + Y F C P
Sbjct: 780 GDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGI 839
Query: 399 PDSGDVTVMDLHSGGVAHFHCHLGY-ELQGAKMLTCI-NASKPHWSSQEPICSAPCGGAV 456
P + + G C G+ + QG + +TCI K WS P C APCGG
Sbjct: 840 PINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGH- 898
Query: 457 HNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH-DKDRMTVHSGQTNK 515
+A G +LSP +P S C W IEA G + + FER + D + VH G
Sbjct: 899 FSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLL 958
Query: 516 SALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG--HCYEPYIQ 573
S LL S VP + L S N I + FT+D +R+ + F I +E+ C +P I
Sbjct: 959 SPLL-GSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 1016
Query: 574 -NGNFTTSDPTYNIGTIVEFTCDPGHSL-EQGPAIIECINVRDPYWNDTEPLCRAMCGGE 631
+G D ++IG+ V F+CD G+ L + P + E ++ +W+ P C A+CGG+
Sbjct: 1017 VHGRRYGHD--FSIGSTVSFSCDSGYRLSHEEPLLCE----KNHWWSHPLPTCDALCGGD 1070
Query: 632 LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYD----- 685
+ +G +LSP +PE Y +C W + V K + + +L + D L I +
Sbjct: 1071 VRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFT 1130
Query: 686 -------GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIE 738
G ++ P I GN Q + S D +I + +GF + + E
Sbjct: 1131 QPLARLTGSDLPPTINAGLYGNFRAQLRFIS--DFSISY------------EGFNITFSE 1176
Query: 739 VSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD--LSWSSD 796
+ + C D Q G + + + G +T+ C GY + G+ + C WS+
Sbjct: 1177 YNL-EPCEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAP 1233
Query: 797 PPFC-----------EKIMYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCN-----PGFV 839
P C E I+ + P +++ I + G I + G V
Sbjct: 1234 LPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV 1293
Query: 840 LE----------------GSSLLTCYSRETGTPIWTS------------RLPHCVSEESL 871
L+ G+S+ T +W +L + S E
Sbjct: 1294 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY-TSFELS 1352
Query: 872 ACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
C++PG+P+ GY+I + + G ++ + C G+ L G ++C+ G+ W+ PLP C
Sbjct: 1353 HCEDPGIPQFGYKI-SDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC 1410
Score = 134 bits (336), Expect = 6e-31
Identities = 113/418 (27%), Positives = 178/418 (42%), Gaps = 22/418 (5%)
Query: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPICSA 450
C P P++G D G F C Y LQGAK +TC ++ WS P+C
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQK-LHLHFERLLLH-DKDRMTV 508
G+ G SP++P + + C+W I A K + ++FE L D +T+
Sbjct: 546 KTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTI 605
Query: 509 -HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G+ + L VP + ++S + + + +D++ + F + ++ EK C
Sbjct: 606 GDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
+P D N ++ F C G L G I C + W+ P+C
Sbjct: 665 GDPGTPLYGIREGDGFSN-RDVLRFECQFGFELI-GEKSIVC--QENNQWSANIPICIFP 720
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL-SNSDILTIYDG 686
C +A G VLSP++PE Y +CIW I RI L +L S D L + DG
Sbjct: 721 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG 780
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
D ILG + G P L S++ L ++F +D + G+GF + Y N+ C
Sbjct: 781 DSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHS----MSGRGFNITYNTFGHNE-CP 835
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGY-DIVGSDTLTC---QWDLSWSSDPPFC 800
D N + + +L G+ I+ C+ G+ G++T+TC + WS P C
Sbjct: 836 DPGIPINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 132 bits (332), Expect = 2e-30
Identities = 175/717 (24%), Positives = 286/717 (39%), Gaps = 84/717 (11%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSD-GELLSI 337
ALC + + G I S YP NF +C + V V G G+ + + + +++
Sbjct: 2281 ALCGGNITAMNGTIYSPGYPD-EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITV 2339
Query: 338 -RGVD--GPTLTVLANQTLLVEGQVIRSPTNTISVYFRT-FQDDGLGTFQLHYQAFMLS- 392
G D P + + T L + + S +N I + F + F G F L Y A+ L
Sbjct: 2340 WDGPDQNSPQIGQFSGNTAL---ESVYSTSNQILIKFHSDFTTSGF--FVLSYHAYQLRV 2394
Query: 393 CNFPRRPDSGDVTVMD--LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
C P + ++ D G + + C G+ L G +LTC + P+C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 451 PC-GGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTV 508
C + + G +LSP YP++ Q C W+I +G + + E + D + V
Sbjct: 2455 LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV 2514
Query: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
+ G +S +L S F + S G+ + +++++D F IR+ AF +C
Sbjct: 2515 YDGPNIQSPVLISLSGDYSSAFN-ITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCS 2570
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY--WNDTEPLCRA 626
P + S + ++V + CD G L G + C Y W+ P C+A
Sbjct: 2571 TPESPPHGYIISQTGGQLNSVVRWACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQA 2629
Query: 627 M-CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVG---EEKRIFL-----DIQFLNLSN 677
+ CG + G +L+ + Y+ G + + G K + D + N +
Sbjct: 2630 ISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2685
Query: 678 SDILTIYDGDEVMPHIL--GQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIM- 734
+ + + IL G++ +G Y + + F DP G G I
Sbjct: 2686 TPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTK----VVFSCDPG--YHGLGPASIEC 2739
Query: 735 --NYIEVSRND-------SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTL 785
N RN+ SC +LP NG K + T G+ + CD G+ +VGS
Sbjct: 2740 LPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSY--GSTAIFTCDLGFMLVGSAVR 2797
Query: 786 TCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSL 845
C WS C +C P E+ + ++I + T + Y CNPGF L GSS+
Sbjct: 2798 ECLSSGLWSESETRC-LAGHCGIP-ELIVNGQVIGENYGYRDTVV-YQCNPGFRLIGSSV 2854
Query: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLP------ENGYQILYKRLYLPGESLTF 899
C W+ +LP CV ++C +PG P NG+ + +TF
Sbjct: 2855 RICQQDHN----WSGQLPSCV---PVSCGHPGSPIYGRTSGNGFNF--------NDVVTF 2899
Query: 900 MCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEGGN 956
C G+ + G +C + W+ P P+CKV S A + E+ +E GN
Sbjct: 2900 SCNIGYLMQGPTKAQCQANR--QWSHPPPMCKVVNCSDPGI--PANSKRESKIEHGN 2952
Score = 93.6 bits (231), Expect = 9e-19
Identities = 133/594 (22%), Positives = 216/594 (36%), Gaps = 72/594 (12%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+SC P P G + + V F C++GY +QG C + WS P+C
Sbjct: 2873 VSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQC--QANRQWSHPPPMCKV 2930
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVHS 510
V+ + G + F T+ + + F +L + +
Sbjct: 2931 -----VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVL-----ICQPN 2980
Query: 511 GQTNK---SALLYDSLQTESVPFEGLLSE----GNTIRIEFTSD-----QARAASTFNIR 558
GQ +K ++ D P L E G+T+ T Q+ N
Sbjct: 2981 GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 3040
Query: 559 FEAFEK-------GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECIN 611
+ + G C +P G+ + + + + V + CD G+ L G C+
Sbjct: 3041 WSGSQPHCSGDATGTCGDPGTP-GHGSRQESNFRTKSTVRYACDTGYILH-GSEERTCL- 3097
Query: 612 VRDPYWNDTEPLCRAM-CG-------GELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE 663
+ W +P C+A+ CG G++ + G S + +EG I G
Sbjct: 3098 -ANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGY-----ILSGPS 3151
Query: 664 KRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSD 720
R + + + I GD +P G G+ G Y P T++ +
Sbjct: 3152 VRQCTANGTWSGTLPNCTIISCGDPGIP-ANGLRYGDDYVVGQNVSYMCQPGYTMELNGS 3210
Query: 721 PAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIV 780
G + R +C P+I NG T G I+Y C PGY++
Sbjct: 3211 RIRTCTINGTW--SGVMPTCRAVTCPTPPQISNG--RLEGTNFDWGFSISYICSPGYELS 3266
Query: 781 GSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVL 840
LTC + +WS + P C +C DPG R + + + ++CN F+L
Sbjct: 3267 FPAVLTCVGNGTWSGEVPQCLP-KFCGDPGIPAQGKR--EGKSFIYQSEVSFSCNFPFIL 3323
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
GSS C + T W+ PHC+ +C+NPG+P +G Q + G + F
Sbjct: 3324 VGSSTRICQADGT----WSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQV-GSVVQFH 3378
Query: 901 CYEGFELMGEVTIRCILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETSLEG 954
C +G L G T C+ W+G P C H+ + E A ++ G
Sbjct: 3379 CKKGHLLQGSTTRTCL--PDLTWSGIQPEC------IPHSCKQPETPAHANVVG 3424
Score = 81.3 bits (199), Expect = 4e-15
Identities = 66/262 (25%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-DRMTVHS 510
CGG + G + SP +P C W I A E ++ + F+ L ++ D ++++
Sbjct: 65 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYD 123
Query: 511 GQTNKSALLYDSLQTESVPFE---GLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G + + + +T F + S + + TSD A +A F + +E + C
Sbjct: 124 GHPHPT-----NFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECI--NVRDPYWNDTEPLCR 625
P + +++G + ++C G+ L+ P + CI +V W+ P+CR
Sbjct: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILDGHPQLT-CIANSVNTASWDFPVPICR 236
Query: 626 A--MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEE----KRIFLDIQ------FL 673
A CGG + +G++ SP++P Y DC W I V E IF D Q +L
Sbjct: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTI-VAEPGDTISLIFTDFQMEEKYDYL 295
Query: 674 NLSNSDILTIY-DGDEVMPHIL 694
+ S+ TI+ G + P I+
Sbjct: 296 EIEGSEPPTIWLSGMNIPPPII 317
Score = 76.3 bits (186), Expect = 1e-13
Identities = 113/532 (21%), Positives = 189/532 (35%), Gaps = 85/532 (15%)
Query: 387 QAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEP 446
+ M+ C P P + ++ G H+ C L G TC HWS +P
Sbjct: 2989 ECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTC--QLNGHWSGSQP 3046
Query: 447 ICSAPCGGAVHN-----------------ATIGRVLSPSYPENTNGSQFCI----WTIEA 485
CS G + +T+ Y + + + C+ WT
Sbjct: 3047 HCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQ 3106
Query: 486 PEGQKLHLHFERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFT 545
PE + + + K + G T S+++Y + EG + G ++R
Sbjct: 3107 PECKAVQCGNPGTTANGK--VFRIDGTTFSSSVIYSCM-------EGYILSGPSVR---- 3153
Query: 546 SDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPA 605
Q A T++ C +P I D Y +G V + C PG+++E +
Sbjct: 3154 --QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDD-YVVGQNVSYMCQPGYTMELNGS 3210
Query: 606 IIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKR 665
I + W+ P CRA+ P +EG + W +
Sbjct: 3211 RIRTCTINGT-WSGVMPTCRAVT---------CPTPPQISNGRLEGTNFDWGFSIS---- 3256
Query: 666 IFLDIQFLNLSNSDILTI-----YDGDEVMPHILGQYLGN---------SGPQKLYSSTP 711
++ LS +LT + G+ +P L ++ G+ G +Y S
Sbjct: 3257 -YICSPGYELSFPAVLTCVGNGTWSGE--VPQCLPKFCGDPGIPAQGKREGKSFIYQSEV 3313
Query: 712 DLTIQFHSDPAGLIF------GKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR 765
+ F G G G + IE ++ SC + ++G + + V
Sbjct: 3314 SFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT-SCENPGVPRHGSQNNTFGFQV- 3371
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G+ + + C G+ + GS T TC DL+WS P C I + E ++ +
Sbjct: 3372 GSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPEC--IPHSCKQPETPAHANVVGMDLPS 3429
Query: 826 VGTTIQYTCNPGFVLE-GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
G T+ YTC PGF L G+ C S T WT ++P C + + +P
Sbjct: 3430 HGYTLIYTCQPGFFLAGGTEHRVCRSDNT----WTGKVPICEAGSKILVKDP 3477
Score = 70.1 bits (170), Expect = 1e-11
Identities = 109/455 (23%), Positives = 162/455 (35%), Gaps = 102/455 (22%)
Query: 382 FQLHYQAFMLS-CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCI--NASK 438
F+++Y+ S C P P G + G + C GY L G LTCI + +
Sbjct: 166 FKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNT 225
Query: 439 PHWSSQEPICSA--PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
W PIC A CGG + ++ G + SPS+P + + C WTI A G + L F
Sbjct: 226 ASWDFPVPICRAEDACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFT 284
Query: 497 RLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFN 556
+ +K YD L+ E SE TI + S N
Sbjct: 285 DFQMEEK----------------YDYLEIEG-------SEPPTIWL----------SGMN 311
Query: 557 IRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY 616
I P I N N+ + F D H A PY
Sbjct: 312 IP----------PPIISNKNWLR----------LHFVTDSNHRYRGFSA---------PY 342
Query: 617 WNDTEPLCRAMCGGELS----AVAGVVLSPNWPEPYVEGEDCIWKIH-VGEEKRIFLDIQ 671
+ L GEL G + + P IH + EE+R +Q
Sbjct: 343 -QGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQR----VQ 397
Query: 672 FLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKG 729
+L NS + D + PH P+ + T +L + H + F K
Sbjct: 398 VTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDF-KS 456
Query: 730 QGF-------------IMNYIEV-SRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDP 775
+GF I+N + + ++ C D E +NG + S L G+ + + CD
Sbjct: 457 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDE 514
Query: 776 GYDIVGSDTLTCQ----WDLSWSSDPPFCEKIMYC 806
Y + G+ ++TCQ +WS P C K+ C
Sbjct: 515 DYVLQGAKSITCQRIAEVFAAWSDHRPVC-KVKTC 548
Score = 70.1 bits (170), Expect = 1e-11
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
+ YQC+PG+ ++GS CQ D +WS P C + C PG + S
Sbjct: 2839 VVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVS-CGHPGSPIYGR--TSGNGFNFND 2895
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQ--IL 886
+ ++CN G++++G + C + W+ P C + + C +PG+P N + +
Sbjct: 2896 VVTFSCNIGYLMQGPTKAQCQANRQ----WSHPPPMC---KVVNCSDPGIPANSKRESKI 2948
Query: 887 YKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPS-HWNGPLPVC 930
+ G + + C G+ L G + C QP+ W+ PLP C
Sbjct: 2949 EHGNFTYGTVVFYDCNPGYFLFGSSVLIC---QPNGQWDKPLPEC 2990
Score = 62.4 bits (150), Expect = 2e-09
Identities = 57/200 (28%), Positives = 82/200 (41%), Gaps = 14/200 (7%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-DILTIYDG 686
CGG L + G + SP +P Y G +C W I E RI + Q L D L++YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
+ + G P + S+ +++ SD A GF + Y E+ ++ SC
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFA----VSAHGFKVYYEEL-QSSSCG 179
Query: 747 DLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD----LSWSSDPPFCEK 802
+ G T G +I Y C GY + G LTC + SW P C
Sbjct: 180 NPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
Query: 803 IMYCTDPGEVDHSTRLISDP 822
C G + S+ +IS P
Sbjct: 238 EDAC--GGTMRGSSGIISSP 255
Score = 45.4 bits (106), Expect = 3e-04
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C DPGE ++ R+ SD +G+T+Q++C+ +VL+G+ +TC W+ P C
Sbjct: 486 CPDPGEPENGKRIGSD--FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 543
Score = 44.3 bits (103), Expect = 6e-04
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILG--QPSHWNGP 926
+S +C NPG+P G +LY + G+ + + C G+ L G + CI + W+ P
Sbjct: 174 QSSSCGNPGVPPKG--VLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFP 231
Query: 927 LPVCK 931
+P+C+
Sbjct: 232 VPICR 236
Score = 40.0 bits (92), Expect = 0.011
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEES 870
VG I+Y+C G++L+G LTC + T W +P C +E++
Sbjct: 196 VGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDA 240
Score = 37.4 bits (85), Expect = 0.073
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC--ILGQPSHW 923
+ S C +PG PENG +I + G ++ F C E + L G +I C I + W
Sbjct: 479 IKTASNLCPDPGEPENGKRI--GSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAW 536
Query: 924 NGPLPVCKV 932
+ PVCKV
Sbjct: 537 SDHRPVCKV 545
Score = 35.4 bits (80), Expect = 0.28
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)
Query: 869 ESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLP 928
E +C +PG P Y I + + L F C GFEL+GE +I C + + W+ +P
Sbjct: 660 EKESCGDPGTPL--YGIREGDGFSNRDVLRFECQFGFELIGEKSIVC--QENNQWSANIP 715
Query: 929 VC 930
+C
Sbjct: 716 IC 717
Score = 33.5 bits (75), Expect = 1.1
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 894 GESLTFMCYEGFELMGEVTIRC--ILGQPSHWNGPLPVCKV 932
G S+ F C G+ L G + IRC + + WN LP C V
Sbjct: 1897 GSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIV 1937
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 107 bits (266), Expect = 7e-23
Identities = 146/612 (23%), Positives = 227/612 (37%), Gaps = 165/612 (26%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+ C P P++G + G F C GY+L G +TC+ + + W+ P C A
Sbjct: 1787 IKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE--WNHLIPYCKA 1844
Query: 451 -PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER--LLLHDKDRMT 507
CG P+ PEN CI + G K+ + L DK+
Sbjct: 1845 VSCG------------KPAIPENG-----CIEELAFTFGSKVTYRCNKGYTLAGDKE--- 1884
Query: 508 VHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
S+ L +S + S P + + +S NI
Sbjct: 1885 --------SSCLANSSWSHSPP---------------VCEPVKCSSPENIN--------- 1912
Query: 568 YEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM 627
NG + S TY + ++CD G+SL QGP+IIEC W+ P C +
Sbjct: 1913 ------NGKYILSGLTYL--STASYSCDTGYSL-QGPSIIEC--TASGIWDRAPPACHLV 1961
Query: 628 CGGELSAVAGVVLSPN-----------WPEPY-VEGEDCI-------WKI---------- 658
GE A+ V++ N E Y + G D I W
Sbjct: 1962 FCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 2021
Query: 659 -------HVGEEK--RIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSG------- 702
H E R+F DI F S D ++ D +++ + G+++ G
Sbjct: 2022 DEPPIVDHASPETAHRLFGDIAFYYCS--DGYSLADNSQLLCNAQGKWVPPEGQDMPRCI 2079
Query: 703 -------PQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNY---IEVSRNDS-------- 744
P YS ++ + + + F +GF++N IE R
Sbjct: 2080 AHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSI 2139
Query: 745 ------CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPP 798
C + P I NG+ + S+ GA + Y C+ G+ I G TC+ WSS P
Sbjct: 2140 QCIPVRCGEPPSIMNGYASGSNYSF--GAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIP 2197
Query: 799 FCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRET 853
C + C +P G ++H+T I + + ++Y CNPG+ GS + C +
Sbjct: 2198 TCHPVS-CGEPPKVENGFLEHTTGRIFE------SEVRYQCNPGYKSVGSPVFVCQANRH 2250
Query: 854 GTPIWTSRLP-HCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVT 912
W S P CV L C P +NG+ + + G + F C EG+EL+G+ +
Sbjct: 2251 ----WHSESPLMCV---PLDCGKPPPIQNGF--MKGENFEVGSKVQFFCNEGYELVGDSS 2301
Query: 913 IRCILGQPSHWN 924
C + WN
Sbjct: 2302 WTC--QKSGKWN 2311
Score = 93.6 bits (231), Expect = 9e-19
Identities = 60/190 (31%), Positives = 93/190 (48%), Gaps = 15/190 (7%)
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
SC + P+++NG+ + T + + + YQC+PGY VGS CQ + W S+ P
Sbjct: 2203 SCGEPPKVENGFLEHT-TGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVP 2261
Query: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL- 862
+ C P + + + VG+ +Q+ CN G+ L G S TC +++G W +
Sbjct: 2262 LDCGKPPPIQNG--FMKGENFEVGSKVQFFCNEGYELVGDSSWTC--QKSGK--WNKKSN 2315
Query: 863 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 922
P C+ + C P L EN Q++ K L +TF C EG L G ++C+ Q
Sbjct: 2316 PKCMPAK---CPEPPLLEN--QLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQ--Q 2368
Query: 923 WNGPLPVCKV 932
WN PVCK+
Sbjct: 2369 WNDSFPVCKI 2378
Score = 89.7 bits (221), Expect = 1e-17
Identities = 62/232 (26%), Positives = 92/232 (39%), Gaps = 51/232 (21%)
Query: 740 SRNDSCSDLPEIQNGWK--TTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDP 797
S++ CSD P + T+ +L G+++ CDPG+ +VG+ C W+
Sbjct: 1623 SKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPL 1682
Query: 798 PFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPI 857
P CE+I C P +++ D G+T+ Y CN G+ L G S + C T
Sbjct: 1683 PHCERIS-CGVPPPLENGFHSADD--FYAGSTVTYQCNNGYYLLGDSRMFC----TDNGS 1735
Query: 858 WTSRLPHCVS--------------------------------------EESLACDNPGLP 879
W P C+ E + C PG P
Sbjct: 1736 WNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNP 1795
Query: 880 ENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
ENG+ +Y G +TF C EG++LMG I C+ + WN +P CK
Sbjct: 1796 ENGHSS--GEIYTVGAEVTFSCQEGYQLMGVTKITCL--ESGEWNHLIPYCK 1843
Score = 85.5 bits (210), Expect = 2e-16
Identities = 55/163 (33%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
+T+ C G+ + G L C W+ P C KI+ CT P + + S L G+
Sbjct: 2345 VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVC-KIVLCTPPPLISFGVPIPSS-ALHFGS 2402
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYK 888
T++Y+C GF L G+S C T W+S LP CV E C P NG +
Sbjct: 2403 TVKYSCVGGFFLRGNSTTLCQPDGT----WSSPLPECVPVE---CPQPEEIPNGIIDVQG 2455
Query: 889 RLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
YL + + C GFEL+G T C G+ HW G P CK
Sbjct: 2456 LAYL--STALYTCKPGFELVGNTTTLC--GENGHWLGGKPTCK 2494
Score = 85.5 bits (210), Expect = 2e-16
Identities = 54/160 (33%), Positives = 78/160 (48%), Gaps = 15/160 (9%)
Query: 771 YQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTI 830
Y C PG+++VG+ T C + W P C K + C P E+ + +D L G T+
Sbjct: 2464 YTCKPGFELVGNTTTLCGENGHWLGGKPTC-KAIECLKPKEILNGKFSYTD--LHYGQTV 2520
Query: 831 QYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRL 890
Y+CN GF LEG S LTC ETG W P C ++ CD+P ENG+ +
Sbjct: 2521 TYSCNRGFRLEGPSALTCL--ETGD--WDVDAPSC---NAIHCDSPQPIENGF--VEGAD 2571
Query: 891 YLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Y G + + C+ GF++ G C + S W+ +P C
Sbjct: 2572 YSYGAIIIYSCFPGFQVAGHAMQTC---EESGWSSSIPTC 2608
Score = 85.5 bits (210), Expect = 2e-16
Identities = 125/551 (22%), Positives = 205/551 (37%), Gaps = 54/551 (9%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+ C+ P+ ++G V D G + + C G+++ G M TC + WSS P C
Sbjct: 2554 IHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG---WSSSIPTCMP 2610
Query: 451 PCGGAVHNATIGRVLS----PSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRM 506
G + G Y E + + P HL +
Sbjct: 2611 IDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPP---YHLGAVAKTWEN---- 2663
Query: 507 TVHSGQTNKSALLYDSLQTESV-PFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
T S T+ S LY ++ + + P LL I E + A S +I
Sbjct: 2664 TKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIE------- 2716
Query: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P F T ++G+ V+++C PGH L G + C+ R W+ P C
Sbjct: 2717 -CDLPTAPENGFLRFTET-SMGSAVQYSCKPGHILA-GSDLRLCLENRK--WSGASPRCE 2771
Query: 626 AM-CGGELSAVAGVVLSPNWPEPYVEGEDCI-WKIHVGEEKRIFLDIQFLNLSNSDILTI 683
A+ C + G + N+ +C + G E+R D + + + I
Sbjct: 2772 AISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWD-EDEPICIP 2830
Query: 684 YDGDEVMPHILGQYLGNS---GPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS 740
D GQ G+ + Y+ ++ L G G + + V
Sbjct: 2831 VDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVR 2890
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
C+ P++ NG T + +T+ C GY + G+ LTCQ D +W ++ P C
Sbjct: 2891 ----CATPPQLANG--VTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2944
Query: 801 EKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS 860
K + C P ++ H + + G IQY C PG+ L G+S C S + W+
Sbjct: 2945 -KPVNCGPPEDLAHG--FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGS----WSG 2997
Query: 861 RLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQP 920
P C+ C P + Y + + G++ C++GF+L+G I C
Sbjct: 2998 SSPSCL---PCRCSTPVIE---YGTVNGTDFDCGKAARIQCFKGFKLLGLSEITC--EAD 3049
Query: 921 SHWNGPLPVCK 931
W+ P C+
Sbjct: 3050 GQWSSGFPHCE 3060
Score = 83.6 bits (205), Expect = 9e-16
Identities = 95/419 (22%), Positives = 156/419 (37%), Gaps = 84/419 (20%)
Query: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR- 625
C EP + + T +G +V F+C GH L QGP++++C+ + WND+ P+C+
Sbjct: 2323 CPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVL-QGPSVLKCLPSQQ--WNDSFPVCKI 2378
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYD 685
+C GV + + +H G + F NS L D
Sbjct: 2379 VLCTPPPLISFGVPIPSS-------------ALHFGSTVKYSCVGGFFLRGNSTTLCQPD 2425
Query: 686 GDEVMPHILGQYLGNSGPQKLYSSTPDL-------TIQFHSDPAGLIFGKG------QGF 732
G P + P+++ + D+ T + P + G G
Sbjct: 2426 GTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGH 2485
Query: 733 IMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLS 792
+ + C EI NG S+T+L G +TY C+ G+ + G LTC
Sbjct: 2486 WLGGKPTCKAIECLKPKEILNG--KFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGD 2543
Query: 793 WSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRE 852
W D P C I +C P +++ + G I Y+C PGF + G ++ TC E
Sbjct: 2544 WDVDAPSCNAI-HCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTC--EE 2598
Query: 853 TGTPIWTSRLPHCV-------------------------SEESLACDNPGL-PENGYQI- 885
+G W+S +P C+ +E + P + P Y +
Sbjct: 2599 SG---WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLG 2655
Query: 886 --------------LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
+ +L G +++ C G+EL+G + C + WNG P C
Sbjct: 2656 AVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLIC--QEDGTWNGSAPSC 2712
Score = 73.6 bits (179), Expect = 9e-13
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 16/195 (8%)
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSD 796
+ + + C E NG + G + Y C+ GY + G C + +WS
Sbjct: 3291 VAICKETRCETPLEFLNGKADIENR--TTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHP 3348
Query: 797 PPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
P C K C P + + L+S+ V + C GF+L+G ++TC ET
Sbjct: 3349 VPLC-KPNPCPVPFVIPENA-LLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDET--- 3403
Query: 857 IWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
WT C E ++C P EN I Y G+ +T+ CY G+ L G + C+
Sbjct: 3404 -WTQTSAKC---EKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLEGFLRSVCL 3457
Query: 917 LGQPSHWNGPLPVCK 931
+ W P P+C+
Sbjct: 3458 --ENGTWTSP-PICR 3469
Score = 70.1 bits (170), Expect = 1e-11
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 14/165 (8%)
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
GA +T+ C GY ++G +TC W+ P+C K + C P ++ I +
Sbjct: 1808 GAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC-KAVSCGKPAIPENG--CIEELAFT 1864
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI 885
G+ + Y CN G+ L G +C + + W+ P C E + C +P NG I
Sbjct: 1865 FGSKVTYRCNKGYTLAGDKESSCLANSS----WSHSPPVC---EPVKCSSPENINNGKYI 1917
Query: 886 LYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
L YL + ++ C G+ L G I C W+ P C
Sbjct: 1918 LSGLTYL--STASYSCDTGYSLQGPSIIECTAS--GIWDRAPPAC 1958
Score = 67.0 bits (162), Expect = 9e-11
Identities = 47/148 (31%), Positives = 71/148 (47%), Gaps = 13/148 (8%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGT 828
I YQC+PGY++ G+ CQ + WS C++ C P E + I + G
Sbjct: 3263 IIYQCEPGYELEGNRERVCQENRQWSGGVAICKETR-CETPLEFLNGKADIENRT--TGP 3319
Query: 829 TIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP-GLPENGYQILY 887
+ Y+CN G+ LEG S C E GT W+ +P C + C P +PEN +L
Sbjct: 3320 NVVYSCNRGYSLEGPSEAHC--TENGT--WSHPVPLC---KPNPCPVPFVIPENA--LLS 3370
Query: 888 KRLYLPGESLTFMCYEGFELMGEVTIRC 915
++ + ++++ C EGF L G I C
Sbjct: 3371 EKEFYVDQNVSIKCREGFLLQGHGIITC 3398
Score = 64.7 bits (156), Expect = 4e-10
Identities = 85/375 (22%), Positives = 151/375 (40%), Gaps = 41/375 (10%)
Query: 567 CYEPY-IQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C +P + NG+ S+ TY + T+ + CDPG+ L G C + D W++ EP+C
Sbjct: 2775 CKKPNPVMNGSIKGSNYTY-LSTLY-YECDPGYVLN-GTERRTCQD--DKNWDEDEPICI 2829
Query: 626 AM-CGGELSAVAGVVLSPNWP-EPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTI 683
+ C + G V + + +E + G R+ L + + D + +
Sbjct: 2830 PVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPV 2889
Query: 684 YDGDEVMPHILGQYLGNSGPQKL-YSSTPDLTIQFHSDPAGLIFG------KGQGFIMNY 736
L N + L Y ++T FH ++ G + G
Sbjct: 2890 RCATPPQ-------LANGVTEGLDYGFMKEVT--FHCHEGYILHGAPKLTCQSDGNWDAE 2940
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSD 796
I + + +C ++ +G+ + + G I YQC PGY + G+ + C + SWS
Sbjct: 2941 IPLCKPVNCGPPEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGS 2998
Query: 797 PPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
P C C+ P +++ T ++ G + C GF L G S +TC +
Sbjct: 2999 SPSCLPCR-CSTP-VIEYGT--VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQ--- 3051
Query: 857 IWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
W+S PHC E +C + + N + + + +T+ C G+ + G + C
Sbjct: 3052 -WSSGFPHC---EHTSCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICT 3105
Query: 917 LGQPSHWNGPLPVCK 931
+ W+ P PVC+
Sbjct: 3106 --EKGVWSQPYPVCE 3118
Score = 60.1 bits (144), Expect = 1e-08
Identities = 43/169 (25%), Positives = 70/169 (41%), Gaps = 18/169 (10%)
Query: 768 RITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI---MYCTDPGEVDHSTRLISDPVL 824
+++ C GY G + CQ D +W +PPF ++ + C P +H +
Sbjct: 3202 QVSVSCAEGYTFEGVNISVCQLDGTW--EPPFSDESCSPVSCGKPESPEHG--FVVGSKY 3257
Query: 825 LVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQ 884
+TI Y C PG+ LEG+ C W+ + C + C+ P NG
Sbjct: 3258 TFESTIIYQCEPGYELEGNRERVCQENRQ----WSGGVAIC---KETRCETPLEFLNGKA 3310
Query: 885 ILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKVN 933
+ R G ++ + C G+ L G C + W+ P+P+CK N
Sbjct: 3311 DIENR--TTGPNVVYSCNRGYSLEGPSEAHCT--ENGTWSHPVPLCKPN 3355
Score = 57.0 bits (136), Expect = 9e-08
Identities = 50/191 (26%), Positives = 74/191 (38%), Gaps = 12/191 (6%)
Query: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
C L +NG+ + A +C PG+D+VGS + C + WS +C ++
Sbjct: 378 CPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYC-RVR 436
Query: 805 YCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPH 864
C + H S +L TT C+ G+ LEGS LTC G W P
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC----QGNSQWDGPEPR 492
Query: 865 CVSEESLACDNPGLPENGYQILYKRLYLPGESLTF---MCYEGFELMG-EVTIRCILGQP 920
CV C +P++ + P + T C +GF L G + +RC
Sbjct: 493 CVERH---CSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGK 549
Query: 921 SHWNGPLPVCK 931
+ VCK
Sbjct: 550 WNVGVQAAVCK 560
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
+C L + ++G + S E++ CD GY + GSD LTCQ + W P C +
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVE- 495
Query: 804 MYCTD---PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEG-SSLLTC 848
+C+ P +V S GT +C GF+L G +L C
Sbjct: 496 RHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRC 544
Score = 45.4 bits (106), Expect = 3e-04
Identities = 59/211 (27%), Positives = 81/211 (38%), Gaps = 31/211 (14%)
Query: 744 SCSDLPEIQNGW--KTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
SC LP I N + +T+S E V ITY C GY I GS L C WS P CE
Sbjct: 3063 SCGSLPMIPNAFISETSSWKENV----ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCE 3118
Query: 802 KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSR 861
+ C P V + + + + ++ C LEG Y+ +T T +T +
Sbjct: 3119 PLS-CGSPPSV--ANAVATGEAHTYESEVKLRC-----LEG------YTMDTDTDTFTCQ 3164
Query: 862 LPHCVSEESLACD--NPGLPENGYQIL-YKRLYLPGESLTFMCYEGFELMGEVTIRCILG 918
E ++C LPEN IL + + ++ C EG+ G C L
Sbjct: 3165 KDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL- 3223
Query: 919 QPSHWNGPL------PVCKVNQDSFEHALEV 943
W P PV +S EH V
Sbjct: 3224 -DGTWEPPFSDESCSPVSCGKPESPEHGFVV 3253
Score = 39.7 bits (91), Expect = 0.015
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+ C P+ +G + DLH G + C+ G+ L+G LTC+ W P C+A
Sbjct: 2496 IECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETG--DWDVDAPSCNA 2553
Score = 32.7 bits (73), Expect = 1.8
Identities = 59/262 (22%), Positives = 93/262 (35%), Gaps = 52/262 (19%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSS-----QE 445
+SC P P+ G V + C GYEL+G + C WS +E
Sbjct: 3239 VSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC--QENRQWSGGVAICKE 3296
Query: 446 PICSAPC----GGA-VHNATIG--------RVLSPSYPENTNGSQFCIWTIEAP--EGQK 490
C P G A + N T G R S P + ++ W+ P +
Sbjct: 3297 TRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNP 3356
Query: 491 LHLHF---ERLLLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSD 547
+ F E LL +K+ Y EG L +G+ I I D
Sbjct: 3357 CPVPFVIPENALLSEKE--------------FYVDQNVSIKCREGFLLQGHGI-ITCNPD 3401
Query: 548 QARAASTFNIRFEAFEKGHCYEP-YIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAI 606
+ T+ EK C P +++N Y G ++ ++C G+ LE
Sbjct: 3402 E-----TWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE---GF 3451
Query: 607 IECINVRDPYWNDTEPLCRAMC 628
+ + + + W + P+CRA+C
Sbjct: 3452 LRSVCLENGTWT-SPPICRAVC 3472
Score = 32.3 bits (72), Expect = 2.3
Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
+SC P ++G + D ++G + C+ GY L G + C + W+ P C
Sbjct: 1688 ISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGS--WNGVSPSC 1743
Score = 31.6 bits (70), Expect = 4.0
Identities = 29/137 (21%), Positives = 49/137 (35%), Gaps = 23/137 (16%)
Query: 318 YGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDD 377
Y + V + G ++S + ++G L A + GQ SP
Sbjct: 2091 YSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSP-------------- 2136
Query: 378 GLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINAS 437
+ Q + C P +G + + G + + C+ G+ ++G K TC +
Sbjct: 2137 ------MSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTC--EA 2188
Query: 438 KPHWSSQEPIC-SAPCG 453
WSS P C CG
Sbjct: 2189 TGQWSSPIPTCHPVSCG 2205
Score = 30.8 bits (68), Expect = 6.8
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 413 GVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
GV F C G+ LQG +L C+ + + W+ P+C
Sbjct: 2343 GVVTFSCKEGHVLQGPSVLKCLPSQQ--WNDSFPVC 2376
Score = 30.4 bits (67), Expect = 8.9
Identities = 18/62 (29%), Positives = 24/62 (38%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
L C P +G + + G F C+ GYEL G TC + K + S A
Sbjct: 2262 LDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPA 2321
Query: 451 PC 452
C
Sbjct: 2322 KC 2323
Score = 30.4 bits (67), Expect = 8.9
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
+SC P ++ + G + + C+ GY L+G C+ W+S PIC A
Sbjct: 3414 ISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGT--WTS-PPICRA 3470
Query: 451 PCGGAVHNATI 461
C N I
Sbjct: 3471 VCRFPCQNGGI 3481
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 105 bits (262), Expect = 2e-22
Identities = 109/461 (23%), Positives = 184/461 (39%), Gaps = 68/461 (14%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGY--GVELQVKSVNLSDG---E 333
A C + G I S +YP EC + +TV G+ G+ Q + D +
Sbjct: 462 ATCGGDMNKDAGQIQSPNYPD-DYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 334 LLSIRGVDGPT--LTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
L +R DGPT ++ + + + ++S +N + + F + F ++ +
Sbjct: 521 YLEVR--DGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVD 578
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
C++P D G +++ G C GYEL K + C
Sbjct: 579 ECSWP---DHGGCEHRCVNTLGSYKCACDPGYELAADKKM----------------CEVA 619
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDR-----M 506
CGG + G + SP +P+ ++ C+W + AP ++ L FE L D +
Sbjct: 620 CGGFITKLN-GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFV 678
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V SG + A L+ P E + S+ N +R+EF SD + F F + +K
Sbjct: 679 EVRSG-LSPDAKLHGRFCGSETP-EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS-DKDE 735
Query: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYW-NDTEPLCR 625
C + NG + T + C R+ YW ++ C+
Sbjct: 736 CAK---DNGGCQHEC----VNTFGSYLC----------------RCRNGYWLHENGHDCK 772
Query: 626 -AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----D 679
A C ++S+V G + SPNWP+ Y +C W I R+ L + D
Sbjct: 773 EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYD 832
Query: 680 ILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
L +YDG + + ILG++ G+ P +S + ++F+SD
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSD 873
Score = 52.4 bits (124), Expect = 2e-06
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 9/131 (6%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
CG L G +P +P Y C+W+I V ++I L+ ++L S D +
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRN 742
+ DG +LG++ G+ P+ L S+ L ++F S L G+GF Y
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNIL----GKGFFAAYEATCGG 466
Query: 743 DSCSDLPEIQN 753
D D +IQ+
Sbjct: 467 DMNKDAGQIQS 477
Score = 39.7 bits (91), Expect = 0.015
Identities = 76/345 (22%), Positives = 118/345 (34%), Gaps = 86/345 (24%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRM 506
CG + + T G +P +P C+W I G+K+ L+F + L D +
Sbjct: 351 CGETLQDTT-GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V G K+ LL + +P E L+S + + +EF S F +EA
Sbjct: 410 EVRDGYWRKAPLL-GRFCGDKIP-EPLVSTDSRLWVEFRSSSNILGKGFFAAYEA----- 462
Query: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRA 626
TC G + + I+ N D Y E +
Sbjct: 463 --------------------------TC--GGDMNKDAGQIQSPNYPDDYRPSKECV--- 491
Query: 627 MCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDG 686
W EG HVG + F +I+ + D L + DG
Sbjct: 492 -----------------WRITVSEG------FHVGLTFQAF-EIERHDSCAYDYLEVRDG 527
Query: 687 DEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCS 746
++G + G P+ + SS+ L ++F SD G I GF N+ + D CS
Sbjct: 528 PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSD--GSI--NKAGFAANFFK--EVDECS 581
Query: 747 DLPEIQNGWKT---TSHTELVRGARITYQCDPGYDIVGSDTLTCQ 788
W H + CDPGY++ +D C+
Sbjct: 582 --------WPDHGGCEHRCVNTLGSYKCACDPGYEL-AADKKMCE 617
Score = 32.0 bits (71), Expect = 3.1
Identities = 55/298 (18%), Positives = 105/298 (35%), Gaps = 39/298 (13%)
Query: 281 CSVSFSNPEGYIDSSDYPL-LPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGEL----- 334
C + G I S +P P N C + V Y + LQ + L ++
Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNK--NCVWQVVAPAQYRISLQFEVFELEGNDVCKYDF 677
Query: 335 LSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCN 394
+ +R P + +VI S +N + V F++ F+ H+ + C
Sbjct: 678 VEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC- 736
Query: 395 FPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGG 454
D+G +++ G C GY L + A C
Sbjct: 737 ---AKDNGGCQHECVNTFGSYLCRCRNGYWLH---------------ENGHDCKEAGCAH 778
Query: 455 AVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRMTVH 509
+ + G + SP++P+ + C W I + G ++ L F + D + ++
Sbjct: 779 KISSVE-GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMY 837
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHC 567
G + + +L ++ + ++ G+++ + F SD AS F+A C
Sbjct: 838 DGPDSLAPILGRFCGSKKP--DPTVASGSSMFLRFYSD----ASVQRKGFQAVHSTEC 889
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 102 bits (255), Expect = 1e-21
Identities = 110/469 (23%), Positives = 179/469 (38%), Gaps = 84/469 (17%)
Query: 279 ALCSVSFSNPEGYIDSSDYP--LLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDG---- 332
A+C EG I S +YP P+ EC + +TV Y V L +S +
Sbjct: 460 AICGGEIRKNEGQIQSPNYPDDYRPMK---ECVWKITVSESYHVGLTFQSFEIERHDNCA 516
Query: 333 -ELLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFML 391
+ L +R ++ + + IRS +NT+ + F DG F
Sbjct: 517 YDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTL---WMKFVSDGTVNKAGFAANFFK 573
Query: 392 SCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAP 451
+ +PD G L++ G C GYEL C A
Sbjct: 574 EEDECAKPDRGGCEQRCLNTLGSYQCACEPGYEL----------------GPDRRSCEAA 617
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRM 506
CGG + G + +P +P+ ++ C+W + AP ++ + FE L D +
Sbjct: 618 CGGLLTKLN-GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYV 676
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
+ SG +++S L+ VP E + S+ N +RIEF SD + F F + +K
Sbjct: 677 EIWSGLSSESK-LHGKFCGAEVP-EVITSQFNNMRIEFKSDNTVSKKGFKAHFFS-DKDE 733
Query: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYW--------- 617
C S + G EC+N Y
Sbjct: 734 C-------------------------------SKDNGGCQHECVNTMGSYMCQCRNGFVL 762
Query: 618 NDTEPLCR-AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS 676
+D + C+ A C ++ + +G++ SPNWP+ Y ++C W+I RI L +
Sbjct: 763 HDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIE 822
Query: 677 NS-----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
D L ++DG+ ILG+ GN P L ++ + ++F SD
Sbjct: 823 QHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSD 871
Score = 87.0 bits (214), Expect = 8e-17
Identities = 72/289 (24%), Positives = 121/289 (41%), Gaps = 45/289 (15%)
Query: 447 ICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL--HDK- 503
+ A CGG + G++ SP+YP++ + C+W I E + L F+ + HD
Sbjct: 457 VYEAICGGEIRKNE-GQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNC 515
Query: 504 --DRMTVHSGQTNKSALL-----YDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFN 556
D + V G + S L+ YD E + S NT+ ++F SD + F
Sbjct: 516 AYDYLEVRDGTSENSPLIGRFCGYDKP-------EDIRSTSNTLWMKFVSDGTVNKAGFA 568
Query: 557 IRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPY 616
F E+ C +P G N + C+PG+ L GP
Sbjct: 569 ANFFK-EEDECAKP--DRGG--CEQRCLNTLGSYQCACEPGYEL--GP------------ 609
Query: 617 WNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLS 676
C A CGG L+ + G + +P WP+ Y ++C+W++ + RI + +F L
Sbjct: 610 ---DRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELE 666
Query: 677 NS-----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
+ D + I+ G + G++ G P+ + S ++ I+F SD
Sbjct: 667 GNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSD 715
Score = 49.3 bits (116), Expect = 2e-05
Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 43/302 (14%)
Query: 279 ALCSVSFSNPEGYIDSSDYPL-LPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSI 337
A C + G I + +P P N C + V T Y + ++ + L E+
Sbjct: 616 AACGGLLTKLNGTITTPGWPKEYPPNK--NCVWQVVAPTQYRISVKFEFFELEGNEVCKY 673
Query: 338 RGVDGPTLTVLANQTLL-------VEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFM 390
V+ + L++++ L +VI S N + + F++ F+ H+ +
Sbjct: 674 DYVE--IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDK 731
Query: 391 LSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA 450
C+ +GG H C G+ M C N H ++ A
Sbjct: 732 DECS--------------KDNGGCQH-EC---VNTMGSYMCQCRNGFVLH-DNKHDCKEA 772
Query: 451 PCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DR 505
C +H+ + G + SP++P+ + C W I A G ++ L F + D
Sbjct: 773 ECEQKIHSPS-GLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831
Query: 506 MTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKG 565
+ V G+T KS +L L +P + L++ GN + + F SD AS F+A
Sbjct: 832 LEVFDGETEKSPIL-GRLCGNKIP-DPLVATGNKMFVRFVSD----ASVQRKGFQATHST 885
Query: 566 HC 567
C
Sbjct: 886 EC 887
Score = 47.8 bits (112), Expect = 5e-05
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
CG L G + SP +P Y CIW++ V ++I L+ ++L S D +
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYI---EV 739
+ DG +LG++ G+ P+ L S+ + I+F S + GKG + I E+
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWV--GKGFAAVYEAICGGEI 466
Query: 740 SRNDSCSDLPEIQNGWK 756
+N+ P + ++
Sbjct: 467 RKNEGQIQSPNYPDDYR 483
Score = 39.7 bits (91), Expect = 0.015
Identities = 39/148 (26%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 437 SKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFE 496
SK + + P G + G + SP +P CIW + G+K+ L+F
Sbjct: 333 SKGDIAQARKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFT 392
Query: 497 RLLLHDK-----DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARA 551
+ L+ D + V G KS LL + +P E L S + + IEF S
Sbjct: 393 TMDLYKSSLCWYDYIEVRDGYWRKSPLL-GRFCGDKLP-EVLTSTDSRMWIEFRSSSNWV 450
Query: 552 ASTFNIRFEAFEKGHC--YEPYIQNGNF 577
F +EA G E IQ+ N+
Sbjct: 451 GKGFAAVYEAICGGEIRKNEGQIQSPNY 478
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 100 bits (250), Expect = 5e-21
Identities = 117/471 (24%), Positives = 196/471 (41%), Gaps = 83/471 (17%)
Query: 458 NATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHF-----ERLLLHDKDRMTVHS-G 511
N G++ SP YP++ W I P+G ++ L+F E L + D + V +
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 512 QTNKSALLYDSLQTESVPF-EGLLSEGNTIRIEFTSDQARAA--STFNIRFEAFEKGHCY 568
Q + ++ TE P E +LS G+ + I F SD + + F+ + A + C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEP-LCRAM 627
E + E +CD G C R Y T+ CR
Sbjct: 145 EREDE-----------------ELSCDHYCHNYIGGYYCSC---RFGYILHTDNRTCRVE 184
Query: 628 CGGEL-SAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDG 686
C L + GV+ SP++P PY + +C++ I + E+ +++QF DI I D
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIEL--EEGFMVNLQF-----EDIFDIEDH 237
Query: 687 DEVM-----------PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN 735
EV P +LG + G P+ + + + + I FHSD + G+ +G+ ++
Sbjct: 238 PEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNS----GENRGWRLS 293
Query: 736 YIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGY----DIVGSDT--LTCQW 789
Y + + C +L +G S + ++ CD GY D V DT + C
Sbjct: 294 Y--RAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLK 351
Query: 790 DLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS--DPVLLVGTTIQYTCNPGF---VLEGSS 844
D +WS+ P C KI+ C PGE++H S + + + I+Y+C + + +
Sbjct: 352 DGTWSNKIPTC-KIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTG 410
Query: 845 LLTCYSRETGTPIWTSR-----LPHCVSEESLACDNPGLPENGYQILYKRL 890
+ TC + +W ++ LP C+ E C G P L KR+
Sbjct: 411 IYTC----SAQGVWMNKVLGRSLPTCLPE----C---GQPSRSLPSLVKRI 450
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/367 (22%), Positives = 138/367 (37%), Gaps = 47/367 (12%)
Query: 282 SVSFSNPEGYIDSSDYP-LLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGEL-----L 335
+V +N G I S YP P ++ E T+N+TV G+ ++L NL L +
Sbjct: 21 TVELNNMFGQIQSPGYPDSYPSDS--EVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYV 78
Query: 336 SIRGVDGPTLTVLANQTLLVEG----QVIRSPTNTISVYFRT--FQDDGLGTFQLHYQAF 389
+ D T +T E +V+ SP + +S+ FR+ ++ F HY A
Sbjct: 79 KVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 449
+ R + + G + C GY L + C
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILH----------------TDNRTCR 182
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLL---LHDKDRM 506
C + G + SP +P S C++TIE EG ++L FE + H +
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
+ + E P E + ++ +++ I F SD + + + + A
Sbjct: 243 PYDYIKIKVGPKVLGPFCGEKAP-EPISTQSHSVLILFHSDNSGENRGWRLSYRA-AGNE 300
Query: 567 CYEPYIQ---NGNFTTSDPTYNIGTIVEFTCDPGH-----SLEQGPAIIECINVRDPYWN 618
C P +Q +G S Y V +CD G+ ++E IEC+ +D W+
Sbjct: 301 C--PELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL--KDGTWS 356
Query: 619 DTEPLCR 625
+ P C+
Sbjct: 357 NKIPTCK 363
Score = 37.0 bits (84), Expect = 0.095
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 19/188 (10%)
Query: 631 ELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYD 685
EL+ + G + SP +P+ Y + W I V + RI L NL +S D + +
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET 82
Query: 686 GDEVMPHILGQYLGNS----GPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSR 741
D+V+ G+ ++ G + + S ++I F SD + + GF +Y+ V
Sbjct: 83 EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN--EERFTGFDAHYMAVD- 139
Query: 742 NDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
D C + + + H + C GY I+ +D TC+ + SD F +
Sbjct: 140 VDECKEREDEELSCDHYCHNYI---GGYYCSCRFGY-ILHTDNRTCRVE---CSDNLFTQ 192
Query: 802 KIMYCTDP 809
+ T P
Sbjct: 193 RTGVITSP 200
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 98.6 bits (244), Expect = 3e-20
Identities = 110/447 (24%), Positives = 188/447 (42%), Gaps = 76/447 (17%)
Query: 458 NATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHF-----ERLLLHDKDRMTVHS-G 511
N G++ SP YP++ W I P+G ++ L+F E L + D + V +
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 512 QTNKSALLYDSLQTESVPF-EGLLSEGNTIRIEFTSDQARAA--STFNIRFEAFEKGHCY 568
Q + ++ TE P E +LS G+ + I F SD + + F+ + A + C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEP-LCRAM 627
E + E +CD G C R Y T+ CR
Sbjct: 145 EREDE-----------------ELSCDHYCHNYIGGYYCSC---RFGYILHTDNRTCRVE 184
Query: 628 CGGEL-SAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDG 686
C L + GV+ SP++P PY + +C++ I + E+ +++QF DI I D
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIEL--EEGFMVNLQF-----EDIFDIEDH 237
Query: 687 DEVM-----------PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN 735
EV P +LG + G P+ + + + + I FHSD + G+ +G+ ++
Sbjct: 238 PEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNS----GENRGWRLS 293
Query: 736 YIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGY----DIVGSDT--LTCQW 789
Y + + C +L +G S + ++ CD GY D V DT + C
Sbjct: 294 Y--RAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLK 351
Query: 790 DLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS--DPVLLVGTTIQYTCNPGF---VLEGSS 844
D +WS+ P C KI+ C PGE++H S + + + I+Y+C + + +
Sbjct: 352 DGTWSNKIPTC-KIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTG 410
Query: 845 LLTCYSRETGTPIWTSR-----LPHCV 866
+ TC + +W ++ LP C+
Sbjct: 411 IYTC----SAQGVWMNKVLGRSLPTCL 433
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/367 (22%), Positives = 138/367 (37%), Gaps = 47/367 (12%)
Query: 282 SVSFSNPEGYIDSSDYP-LLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGEL-----L 335
+V +N G I S YP P ++ E T+N+TV G+ ++L NL L +
Sbjct: 21 TVELNNMFGQIQSPGYPDSYPSDS--EVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYV 78
Query: 336 SIRGVDGPTLTVLANQTLLVEG----QVIRSPTNTISVYFRT--FQDDGLGTFQLHYQAF 389
+ D T +T E +V+ SP + +S+ FR+ ++ F HY A
Sbjct: 79 KVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 449
+ R + + G + C GY L + C
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILH----------------TDNRTCR 182
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLL---LHDKDRM 506
C + G + SP +P S C++TIE EG ++L FE + H +
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
+ + E P E + ++ +++ I F SD + + + + A
Sbjct: 243 PYDYIKIKVGPKVLGPFCGEKAP-EPISTQSHSVLILFHSDNSGENRGWRLSYRA-AGNE 300
Query: 567 CYEPYIQ---NGNFTTSDPTYNIGTIVEFTCDPGH-----SLEQGPAIIECINVRDPYWN 618
C P +Q +G S Y V +CD G+ ++E IEC+ +D W+
Sbjct: 301 C--PELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL--KDGTWS 356
Query: 619 DTEPLCR 625
+ P C+
Sbjct: 357 NKIPTCK 363
Score = 37.0 bits (84), Expect = 0.095
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 19/188 (10%)
Query: 631 ELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYD 685
EL+ + G + SP +P+ Y + W I V + RI L NL +S D + +
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET 82
Query: 686 GDEVMPHILGQYLGNS----GPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSR 741
D+V+ G+ ++ G + + S ++I F SD + + GF +Y+ V
Sbjct: 83 EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN--EERFTGFDAHYMAVD- 139
Query: 742 NDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
D C + + + H + C GY I+ +D TC+ + SD F +
Sbjct: 140 VDECKEREDEELSCDHYCHNYI---GGYYCSCRFGY-ILHTDNRTCRVE---CSDNLFTQ 192
Query: 802 KIMYCTDP 809
+ T P
Sbjct: 193 RTGVITSP 200
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 96.7 bits (239), Expect = 1e-19
Identities = 99/378 (26%), Positives = 167/378 (44%), Gaps = 40/378 (10%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLC-RAMCGGELSAVAGVVLSPN 643
+G+ + ++C GH L G + ECI + +W+ P+C R CG + G +S N
Sbjct: 1473 VGSRINYSCTTGHRLI-GHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1531
Query: 644 WPEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMP 691
E + G ++ ++G R ++ SN D + I+ G ++ P
Sbjct: 1532 -RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1590
Query: 692 HILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCS 746
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 1591 PNVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 1648
Query: 747 DLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
PEI +G T SH + G + Y C+PGYD+ G+ +L C WS + P C +
Sbjct: 1649 PPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC-AVKS 1707
Query: 806 CTD-PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPH 864
C D G++ H R++ L +G + + C+ GF L+GSS+ C + +W + +P
Sbjct: 1708 CDDFLGQLPHG-RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS-LWNNSVPV 1765
Query: 865 CVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCYE------GFELMGEVTIRCIL 917
C E + C NP NG +P G+ +++ C F L+GE TIRC
Sbjct: 1766 C---EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1822
Query: 918 GQPSH--WNGPLPVCKVN 933
+ W+ P P C+++
Sbjct: 1823 DPHGNGVWSSPAPRCELS 1840
Score = 88.6 bits (218), Expect = 3e-17
Identities = 79/354 (22%), Positives = 140/354 (39%), Gaps = 69/354 (19%)
Query: 587 GTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPE 646
G+ V ++C+ G L P+ ++ + W+ P+C + ++ N
Sbjct: 1927 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1986
Query: 647 PYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKL 706
+ G ++ H G DG+++ + G + +
Sbjct: 1987 SFHNGTVVTYQCHTGP----------------------DGEQLFELV--------GERSI 2016
Query: 707 YSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSH------ 760
Y ++ D + S P + C+ PE++N + +
Sbjct: 2017 YCTSKDDQVGVWSSPPPRCIS--------------TNKCT-APEVENAIRVPGNRSFFTL 2061
Query: 761 TELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS 820
TE++R ++C PG+ +VGS T+ CQ + W P C ++ C P E+ H +S
Sbjct: 2062 TEIIR-----FRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV--CQPPPEILHGEHTLS 2114
Query: 821 -DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN-PGL 878
G + Y+C P + L G++ L C T W+ P C + +CD+ G
Sbjct: 2115 HQDNFSPGQEVFYSCEPSYDLRGAASLHC----TPQGDWSPEAPRCTVK---SCDDFLGQ 2167
Query: 879 PENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPSHWNGPLPVCK 931
+G +L L L G ++F+C EGF L G C+L G + WN +PVC+
Sbjct: 2168 LPHGRVLLPLNLQL-GAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 2220
Score = 86.7 bits (213), Expect = 1e-16
Identities = 92/376 (24%), Positives = 159/376 (42%), Gaps = 38/376 (10%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLC-RAMCGGELSAVAGVVLSPN 643
+G+ + ++C GH L G + ECI + +W+ P+C R CG + G +S N
Sbjct: 573 VGSRINYSCTTGHRLI-GHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
Query: 644 WPEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMP 691
E + G ++ + G R ++ SN D + I+ G ++ P
Sbjct: 632 -RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 690
Query: 692 HILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCS 746
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 691 PNVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 748
Query: 747 DLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
P++ + +T + G + Y C+PGYD+ G+ ++ C WS P CE +
Sbjct: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKS 807
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C D + R++ L +G + + C+ GF L+GSS C + +W S +P C
Sbjct: 808 CDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSVPVC 866
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMC------YEGFELMGEVTIRCILG 918
E + C +P + NG P G+++ + C F+L+GE TIRC
Sbjct: 867 ---EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 919 QPSH--WNGPLPVCKV 932
+ W+ P P C +
Sbjct: 924 PQGNGVWSSPAPRCGI 939
Score = 86.7 bits (213), Expect = 1e-16
Identities = 92/376 (24%), Positives = 159/376 (42%), Gaps = 38/376 (10%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLC-RAMCGGELSAVAGVVLSPN 643
+G+ + ++C GH L G + ECI + +W+ P+C R CG + G +S N
Sbjct: 1023 VGSRINYSCTTGHRLI-GHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
Query: 644 WPEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMP 691
E + G ++ + G R ++ SN D + I+ G ++ P
Sbjct: 1082 -RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
Query: 692 HILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCS 746
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 1141 PNVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 1198
Query: 747 DLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
P++ + +T + G + Y C+PGYD+ G+ ++ C WS P CE +
Sbjct: 1199 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKS 1257
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C D + R++ L +G + + C+ GF L+GSS C + +W S +P C
Sbjct: 1258 CDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSVPVC 1316
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMC------YEGFELMGEVTIRCILG 918
E + C +P + NG P G+++ + C F+L+GE TIRC
Sbjct: 1317 ---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 1373
Query: 919 QPSH--WNGPLPVCKV 932
+ W+ P P C +
Sbjct: 1374 PQGNGVWSSPAPRCGI 1389
Score = 82.4 bits (202), Expect = 2e-15
Identities = 123/568 (21%), Positives = 204/568 (35%), Gaps = 86/568 (15%)
Query: 392 SCNFPRRPDSGDVTVMD-LHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V V+ + G + C GY L G+ TCI + W ++ PIC
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVH 509
G T G +S TN F H+ ++ + +
Sbjct: 163 RIPCGLPPTITNGDFIS------TNRENF---------------HYGSVVTY-----RCN 196
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
G + E V + N ++ S A N C
Sbjct: 197 PGSGGRKVF-------ELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---------KCTP 240
Query: 570 PYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC 628
P ++NG + + + +++ +VEF C PG + +GP ++C + W P C +C
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALNK--WEPELPSCSRVC 297
Query: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN----SDILTIY 684
V + + + G++ + G + R ++ + + +
Sbjct: 298 QPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVK 356
Query: 685 DGDEVMPHIL-GQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN-YIEVS 740
D+ M +L G+ L Q D Q A G + N + V
Sbjct: 357 SCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 416
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDP------GYDIVGSDTLTCQWDLS- 792
C P I NG T E+ G + Y CDP +D++G T+ C D
Sbjct: 417 EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQG 476
Query: 793 ---WSSDPPFCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSS 844
WSS P C + +C P ++ T P +GT+++Y C P + S
Sbjct: 477 NGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP---IGTSLKYECRPEYYGRPFS 533
Query: 845 LLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEG 904
+TC +W+S C + +C P P NG + + + G + + C G
Sbjct: 534 -ITCLD----NLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTG 584
Query: 905 FELMGEVTIRCIL-GQPSHWNGPLPVCK 931
L+G + CIL G +HW+ P+C+
Sbjct: 585 HRLIGHSSAECILSGNAAHWSTKPPICQ 612
Score = 82.4 bits (202), Expect = 2e-15
Identities = 91/375 (24%), Positives = 158/375 (42%), Gaps = 38/375 (10%)
Query: 587 GTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLC-RAMCGGELSAVAGVVLSPNW 644
G+ ++++C G+ L G + CI D W++ P+C R CG + G +S N
Sbjct: 124 GSQIKYSCTKGYRLI-GSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTN- 181
Query: 645 PEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMPH 692
E + G ++ + G R ++ SN D + I+ G ++ P
Sbjct: 182 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 241
Query: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCSD 747
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 242 NVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 748 LPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYC 806
P++ + +T + G + Y C+PGYD+ G+ ++ C WS P CE + C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKSC 358
Query: 807 TDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCV 866
D + R++ L +G + + C+ GF L+GSS C + +W S +P C
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSVPVC- 416
Query: 867 SEESLACDNPGLPENGYQILYKRLYLP-GESLTFMC------YEGFELMGEVTIRCILGQ 919
E + C +P + NG P G+++ + C F+L+GE TIRC
Sbjct: 417 --EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDP 474
Query: 920 PSH--WNGPLPVCKV 932
+ W+ P P C +
Sbjct: 475 QGNGVWSSPAPRCGI 489
Score = 82.0 bits (201), Expect = 3e-15
Identities = 88/393 (22%), Positives = 162/393 (41%), Gaps = 41/393 (10%)
Query: 567 CYEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P ++NG + + + +++ +VEF C PG ++ GP ++C + W P C
Sbjct: 1588 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK-GPRRVKCQALNK--WEPELPSCS 1644
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFL-------NLSNS 678
+C + G +P+ + + G++ + G + R +
Sbjct: 1645 RVCQPPPEILHGEH-TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1703
Query: 679 DILTIYDGDEVMPH--ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNY 736
+ + D +PH +L G + + ++ S ++ G + N
Sbjct: 1704 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGM-RSLWNNS 1762
Query: 737 IEVSRNDSCSDLPEIQNGWKT-TSHTELVRGARITYQCDPG------YDIVGSDTLTCQW 789
+ V + C + P I NG T T ++ G I+Y CDP ++++G T+ C
Sbjct: 1763 VPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1822
Query: 790 DLS----WSSDPPFCE---KIMYCTDPGEVDHS--TRLISDPVLLVGTTIQYTCNPGFVL 840
D WSS P CE + +C P + + T I+D VGT++ Y C PG+
Sbjct: 1823 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFG 1882
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
+ S ++C +W+S +C +C P P NG + G ++ +
Sbjct: 1883 KMFS-ISCLE----NLVWSSVEDNC---RRKSCGPPPEPFNGMVHINTDTQF-GSTVNYS 1933
Query: 901 CYEGFELMGEVTIRCIL-GQPSHWNGPLPVCKV 932
C EGF L+G + C++ G W+ P+C++
Sbjct: 1934 CNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1966
Score = 81.6 bits (200), Expect = 3e-15
Identities = 88/382 (23%), Positives = 150/382 (39%), Gaps = 51/382 (13%)
Query: 579 TSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC--------GG 630
T + + IGT + + C PG+S P I C+ ++ W + CR G
Sbjct: 58 TDEFEFPIGTYLNYECRPGYSGR--PFSIICL--KNSVWTGAKDRCRRKSCRNPPDPVNG 113
Query: 631 ELSAVAGV---------------VLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL 675
+ + G+ ++ + + G+ IW RI +
Sbjct: 114 MVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIT 173
Query: 676 SNSDILTIYDGDEVMPHILGQYLGNSGPQKLYS--STPDLTIQFHSDPAGLIFGKGQGFI 733
+ I T + + + SG +K++ P + + D G+ G I
Sbjct: 174 NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 233
Query: 734 MNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDPGYDIVGSDTLTCQWDLS 792
+ + C+ P ++NG + + L + ++C PG+ + G + CQ
Sbjct: 234 IP-------NKCTP-PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
Query: 793 WSSDPPFCEKIMYCTDPGEVDHSTRLISD-PVLLVGTTIQYTCNPGFVLEGSSLLTCYSR 851
W + P C ++ C P +V H+ R D G + Y+C PG+ L G++ + C
Sbjct: 286 WEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC--- 340
Query: 852 ETGTPIWTSRLPHCVSEESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGE 910
T W+ P C E +CD+ G NG + L L G + F+C EGF+L G
Sbjct: 341 -TPQGDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGS 395
Query: 911 VTIRCIL-GQPSHWNGPLPVCK 931
C+L G S WN +PVC+
Sbjct: 396 SASYCVLAGMESLWNSSVPVCE 417
Score = 79.3 bits (194), Expect = 2e-14
Identities = 90/388 (23%), Positives = 158/388 (40%), Gaps = 62/388 (15%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECINV-RDPYWNDTEPLCRAM-CGGELSAVAGVVL-SP 642
+G V F CD G L+ G ++ C+ V WN++ P+C + C + + G +P
Sbjct: 1728 LGAKVSFVCDEGFRLK-GSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1786
Query: 643 NWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSG 702
+ PY G++ + ++ + ++ + S I D PH G + +
Sbjct: 1787 SGDIPY--GKEISYTCDPHPDRGMTFNL----IGESTIRCTSD-----PHGNGVWSSPAP 1835
Query: 703 -------------PQKLYSSTPDLTIQFHSDPAGL---------IFGKG------QGFIM 734
P++ ++P + I P G FGK + +
Sbjct: 1836 RCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVW 1895
Query: 735 NYIEVS-RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQW---D 790
+ +E + R SC PE NG +T+ G+ + Y C+ G+ ++GS + TC +
Sbjct: 1896 SSVEDNCRRKSCGPPPEPFNGM-VHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNN 1954
Query: 791 LSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL-VGTTIQYTCNPG------FVLEGS 843
++W P CE I+ C P + + ++ GT + Y C+ G F L G
Sbjct: 1955 VTWDKKAPICE-IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGE 2013
Query: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCY 902
+ C S++ +W+S P C+S C P + EN ++ R + E + F C
Sbjct: 2014 RSIYCTSKDDQVGVWSSPPPRCISTNK--CTAPEV-ENAIRVPGNRSFFTLTEIIRFRCQ 2070
Query: 903 EGFELMGEVTIRCILGQPSHWNGPLPVC 930
GF ++G T++C W LP C
Sbjct: 2071 PGFVMVGSHTVQCQTN--GRWGPKLPHC 2096
Score = 77.0 bits (188), Expect = 8e-14
Identities = 88/391 (22%), Positives = 151/391 (38%), Gaps = 42/391 (10%)
Query: 567 CYEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P ++NG + + + +++ +VEF C PG + +GP ++C + W P C
Sbjct: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALNK--WEPELPSCS 744
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN----SDIL 681
+C V + + + G++ + G + R ++ + +
Sbjct: 745 RVCQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Query: 682 TIYDGDEVMPHIL-GQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN-YI 737
+ D+ M +L G+ L Q D Q A G + N +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDP------GYDIVGSDTLTCQWD 790
V C P I NG T E+ G + Y CDP +D++G T+ C D
Sbjct: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 791 LS----WSSDPPFCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLE 841
WSS P C + +C P ++ T P +GT+++Y C P +
Sbjct: 924 PQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP---IGTSLKYECRPEYYGR 980
Query: 842 GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMC 901
S +TC +W+S C + +C P P NG + + + G + + C
Sbjct: 981 PFS-ITCLD----NLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 1031
Query: 902 YEGFELMGEVTIRCIL-GQPSHWNGPLPVCK 931
G L+G + CIL G +HW+ P+C+
Sbjct: 1032 TTGHRLIGHSSAECILSGNAAHWSTKPPICQ 1062
Score = 77.0 bits (188), Expect = 8e-14
Identities = 88/391 (22%), Positives = 151/391 (38%), Gaps = 42/391 (10%)
Query: 567 CYEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P ++NG + + + +++ +VEF C PG + +GP ++C + W P C
Sbjct: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALNK--WEPELPSCS 1194
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN----SDIL 681
+C V + + + G++ + G + R ++ + +
Sbjct: 1195 RVCQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 1253
Query: 682 TIYDGDEVMPHIL-GQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN-YI 737
+ D+ M +L G+ L Q D Q A G + N +
Sbjct: 1254 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 1313
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDP------GYDIVGSDTLTCQWD 790
V C P I NG T E+ G + Y CDP +D++G T+ C D
Sbjct: 1314 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 1373
Query: 791 LS----WSSDPPFCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLE 841
WSS P C + +C P ++ T P +GT+++Y C P +
Sbjct: 1374 PQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP---IGTSLKYECRPEYYGR 1430
Query: 842 GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMC 901
S +TC +W+S C + +C P P NG + + + G + + C
Sbjct: 1431 PFS-ITCLD----NLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 1481
Query: 902 YEGFELMGEVTIRCIL-GQPSHWNGPLPVCK 931
G L+G + CIL G +HW+ P+C+
Sbjct: 1482 TTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1512
Score = 76.3 bits (186), Expect = 1e-13
Identities = 55/203 (27%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSWS 794
+V + SC P+ NG T++ G+RI Y C G+ ++G + C WS
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVI-TDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWS 605
Query: 795 SDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTC 848
+ PP C++I P + + G+ + Y CNPG F L G + C
Sbjct: 606 TKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 665
Query: 849 YSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKR-LYLPGESLTFMCYEGFEL 907
S + IW+ P C+ C P + ENG + R L+ E + F C GF +
Sbjct: 666 TSNDDQVGIWSGPAPQCIIPNK--CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVM 722
Query: 908 MGEVTIRCILGQPSHWNGPLPVC 930
G ++C + W LP C
Sbjct: 723 KGPRRVKC--QALNKWEPELPSC 743
Score = 76.3 bits (186), Expect = 1e-13
Identities = 55/203 (27%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSWS 794
+V + SC P+ NG T++ G+RI Y C G+ ++G + C WS
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVI-TDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWS 1055
Query: 795 SDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTC 848
+ PP C++I P + + G+ + Y CNPG F L G + C
Sbjct: 1056 TKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 1115
Query: 849 YSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKR-LYLPGESLTFMCYEGFEL 907
S + IW+ P C+ C P + ENG + R L+ E + F C GF +
Sbjct: 1116 TSNDDQVGIWSGPAPQCIIPNK--CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVM 1172
Query: 908 MGEVTIRCILGQPSHWNGPLPVC 930
G ++C + W LP C
Sbjct: 1173 KGPRRVKC--QALNKWEPELPSC 1193
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/186 (29%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 744 SCSD-LPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQ---WDLSWSSDPPF 799
SC D L ++ +G + L GA++++ CD G+ + G C W+S P
Sbjct: 2160 SCDDFLGQLPHG-RVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPV 2218
Query: 800 CEKIMYCTDPGEV---DHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTCYS 850
CE+I +C +P + H+ D + G I Y C+ F L G S + C S
Sbjct: 2219 CEQI-FCPNPPAILNGRHTGTPFGD--IPYGKEISYACDTHPDRGMTFNLIGESSIRCTS 2275
Query: 851 RETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI-LYKRLYLPGESLTFMCYEGFELMG 909
G +W+S P C AC +P +NG+ I + LYLPG +++++C G+ L+G
Sbjct: 2276 DPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVG 2335
Query: 910 EVTIRC 915
+ I C
Sbjct: 2336 KGFIFC 2341
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 16/203 (7%)
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSWS 794
+V + SC P+ NG T++ G+RI Y C G+ ++G + C WS
Sbjct: 1447 DVCKRKSCKTPPDPVNGMVHVI-TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWS 1505
Query: 795 SDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTC 848
+ PP C++I P + + G+ + Y CN G F L G + C
Sbjct: 1506 TKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYC 1565
Query: 849 YSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKR-LYLPGESLTFMCYEGFEL 907
S + IW+ P C+ C P + ENG + R L+ E + F C GF +
Sbjct: 1566 TSNDDQVGIWSGPAPQCIIPNK--CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVM 1622
Query: 908 MGEVTIRCILGQPSHWNGPLPVC 930
G ++C + W LP C
Sbjct: 1623 KGPRRVKC--QALNKWEPELPSC 1643
Score = 67.0 bits (162), Expect = 9e-11
Identities = 56/183 (30%), Positives = 83/183 (45%), Gaps = 18/183 (9%)
Query: 758 TSHTELVRGARITYQCDPGYDIVGSD-TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHST 816
T+ ++ G + Y+C P Y G ++TC +L WSS C++ T P V+
Sbjct: 1408 TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 1465
Query: 817 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
+I+D + VG+ I Y+C G L G S C T W+++ P C + + C P
Sbjct: 1466 HVITD--IQVGSRINYSCTTGHRLIGHSSAECI-LSGNTAHWSTKPPIC---QRIPCGLP 1519
Query: 877 GLPENGYQILYKR-LYLPGESLTFMCYEG------FELMGEVTIRCILG--QPSHWNGPL 927
NG I R + G +T+ C G FEL+GE +I C Q W+GP
Sbjct: 1520 PTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPA 1579
Query: 928 PVC 930
P C
Sbjct: 1580 PQC 1582
Score = 67.0 bits (162), Expect = 9e-11
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 20/191 (10%)
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G + Y+C PGY +++C +L WSS C + P + + +D
Sbjct: 1869 GTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF- 1926
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENG-YQ 884
G+T+ Y+CN GF L GS TC W + P C E ++C+ P NG +
Sbjct: 1927 -GSTVNYSCNEGFRLIGSPSTTCLVSGNNV-TWDKKAPIC---EIISCEPPPTISNGDFY 1981
Query: 885 ILYKRLYLPGESLTFMCYEG------FELMGEVTIRCIL--GQPSHWNGPLPVC----KV 932
+ + G +T+ C+ G FEL+GE +I C Q W+ P P C K
Sbjct: 1982 SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKC 2041
Query: 933 NQDSFEHALEV 943
E+A+ V
Sbjct: 2042 TAPEVENAIRV 2052
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 758 TSHTELVRGARITYQCDPGYDIVGSD-TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHST 816
T+ ++ G + Y+C P Y G ++TC +L WSS C++ T P V+
Sbjct: 508 TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 565
Query: 817 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
+I+D + VG+ I Y+C G L G S C W+++ P C + + C P
Sbjct: 566 HVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPIC---QRIPCGLP 619
Query: 877 GLPENGYQILYKR-LYLPGESLTFMCYEG------FELMGEVTIRCILG--QPSHWNGPL 927
NG I R + G +T+ C G FEL+GE +I C Q W+GP
Sbjct: 620 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 679
Query: 928 PVC 930
P C
Sbjct: 680 PQC 682
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 758 TSHTELVRGARITYQCDPGYDIVGSD-TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHST 816
T+ ++ G + Y+C P Y G ++TC +L WSS C++ T P V+
Sbjct: 958 TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 1015
Query: 817 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
+I+D + VG+ I Y+C G L G S C W+++ P C + + C P
Sbjct: 1016 HVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPIC---QRIPCGLP 1069
Query: 877 GLPENGYQILYKR-LYLPGESLTFMCYEG------FELMGEVTIRCILG--QPSHWNGPL 927
NG I R + G +T+ C G FEL+GE +I C Q W+GP
Sbjct: 1070 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 1129
Query: 928 PVC 930
P C
Sbjct: 1130 PQC 1132
Score = 57.0 bits (136), Expect = 9e-08
Identities = 72/287 (25%), Positives = 108/287 (37%), Gaps = 55/287 (19%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECINV-RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNW 644
+G V F CD G L+ G + C+ WN + P+C + PN
Sbjct: 2181 LGAKVSFVCDEGFRLK-GRSASHCVLAGMKALWNSSVPVCEQ------------IFCPN- 2226
Query: 645 PEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQ 704
P + G H G F DI + G E+ Y ++ P
Sbjct: 2227 PPAILNGR------HTGTP---FGDIPY-------------GKEI------SYACDTHPD 2258
Query: 705 K--LYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTE 762
+ ++ + +I+ SDP G E+S +C P+IQNG H
Sbjct: 2259 RGMTFNLIGESSIRCTSDPQGNGVWSSPA---PRCELSVPAACPHPPKIQNGHYIGGHVS 2315
Query: 763 L-VRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDH-STRLIS 820
L + G I+Y CDPGY +VG + C WS +C+++ C+ P ++ S L
Sbjct: 2316 LYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV-NCSFPLFMNGISKELEM 2374
Query: 821 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVS 867
V G + C G+ LEGS C + + W L C S
Sbjct: 2375 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR----WDPPLAKCTS 2417
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
Query: 816 TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN 875
T L + +GT + Y C PG+ S++ C +WT C +C N
Sbjct: 55 TNLTDEFEFPIGTYLNYECRPGYSGRPFSII-CLKNS----VWTGAKDRC---RRKSCRN 106
Query: 876 PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPSHWNGPLPVC 930
P P NG + K + G + + C +G+ L+G + CI+ G W+ P+C
Sbjct: 107 PPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 392 SCNFPRRPDSGDVTVM-DLHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V V+ D+ G ++ C G+ L G CI + + HWS++ PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 450 -APCG 453
PCG
Sbjct: 613 RIPCG 617
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 392 SCNFPRRPDSGDVTVM-DLHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V V+ D+ G ++ C G+ L G CI + + HWS++ PIC
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 1062
Query: 450 -APCG 453
PCG
Sbjct: 1063 RIPCG 1067
Score = 36.6 bits (83), Expect = 0.12
Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%)
Query: 392 SCNFPRRPDSGDVTV-MDLHSGGVAHFHCHLGYELQGAKMLTC-INASKPHWSSQEPICS 449
SC P P +G V + D G ++ C+ G+ L G+ TC ++ + W + PIC
Sbjct: 1906 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1965
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKL 491
+ G S + NG+ P+G++L
Sbjct: 1966 IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL 2007
Score = 32.0 bits (71), Expect = 3.1
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-PCGGAVHNATIGRVLSP 467
G + C GY+L+GA L C + WS + P C+ C + GRVL P
Sbjct: 1669 GQEVFYSCEPGYDLRGAASLHC--TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1723
Score = 30.8 bits (68), Expect = 6.8
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-PCGGAVHNATIGRVLSP 467
G + C GY+L+GA + C + WS P C C + GRVL P
Sbjct: 769 GQEVFYSCEPGYDLRGAASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Score = 30.8 bits (68), Expect = 6.8
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-PCGGAVHNATIGRVLSP 467
G + C GY+L+GA + C + WS P C C + GRVL P
Sbjct: 1219 GQEVFYSCEPGYDLRGAASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 1273
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 96.7 bits (239), Expect = 1e-19
Identities = 99/378 (26%), Positives = 167/378 (44%), Gaps = 40/378 (10%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLC-RAMCGGELSAVAGVVLSPN 643
+G+ + ++C GH L G + ECI + +W+ P+C R CG + G +S N
Sbjct: 1023 VGSRINYSCTTGHRLI-GHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
Query: 644 WPEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMP 691
E + G ++ ++G R ++ SN D + I+ G ++ P
Sbjct: 1082 -RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
Query: 692 HILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCS 746
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 1141 PNVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 1198
Query: 747 DLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
PEI +G T SH + G + Y C+PGYD+ G+ +L C WS + P C +
Sbjct: 1199 PPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC-AVKS 1257
Query: 806 CTD-PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPH 864
C D G++ H R++ L +G + + C+ GF L+GSS+ C + +W + +P
Sbjct: 1258 CDDFLGQLPHG-RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS-LWNNSVPV 1315
Query: 865 CVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCYE------GFELMGEVTIRCIL 917
C E + C NP NG +P G+ +++ C F L+GE TIRC
Sbjct: 1316 C---EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 918 GQPSH--WNGPLPVCKVN 933
+ W+ P P C+++
Sbjct: 1373 DPHGNGVWSSPAPRCELS 1390
Score = 88.6 bits (218), Expect = 3e-17
Identities = 79/354 (22%), Positives = 140/354 (39%), Gaps = 69/354 (19%)
Query: 587 GTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPE 646
G+ V ++C+ G L P+ ++ + W+ P+C + ++ N
Sbjct: 1477 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1536
Query: 647 PYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKL 706
+ G ++ H G DG+++ + G + +
Sbjct: 1537 SFHNGTVVTYQCHTGP----------------------DGEQLFELV--------GERSI 1566
Query: 707 YSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSH------ 760
Y ++ D + S P + C+ PE++N + +
Sbjct: 1567 YCTSKDDQVGVWSSPPPRCIS--------------TNKCT-APEVENAIRVPGNRSFFTL 1611
Query: 761 TELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLIS 820
TE++R ++C PG+ +VGS T+ CQ + W P C ++ C P E+ H +S
Sbjct: 1612 TEIIR-----FRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV--CQPPPEILHGEHTLS 1664
Query: 821 -DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN-PGL 878
G + Y+C P + L G++ L C T W+ P C + +CD+ G
Sbjct: 1665 HQDNFSPGQEVFYSCEPSYDLRGAASLHC----TPQGDWSPEAPRCTVK---SCDDFLGQ 1717
Query: 879 PENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPSHWNGPLPVCK 931
+G +L L L G ++F+C EGF L G C+L G + WN +PVC+
Sbjct: 1718 LPHGRVLLPLNLQL-GAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Score = 86.7 bits (213), Expect = 1e-16
Identities = 92/376 (24%), Positives = 159/376 (42%), Gaps = 38/376 (10%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECI-NVRDPYWNDTEPLC-RAMCGGELSAVAGVVLSPN 643
+G+ + ++C GH L G + ECI + +W+ P+C R CG + G +S N
Sbjct: 573 VGSRINYSCTTGHRLI-GHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
Query: 644 WPEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMP 691
E + G ++ + G R ++ SN D + I+ G ++ P
Sbjct: 632 -RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 690
Query: 692 HILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCS 746
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 691 PNVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 748
Query: 747 DLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY 805
P++ + +T + G + Y C+PGYD+ G+ ++ C WS P CE +
Sbjct: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKS 807
Query: 806 CTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHC 865
C D + R++ L +G + + C+ GF L+GSS C + +W S +P C
Sbjct: 808 CDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSVPVC 866
Query: 866 VSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMC------YEGFELMGEVTIRCILG 918
E + C +P + NG P G+++ + C F+L+GE TIRC
Sbjct: 867 ---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 919 QPSH--WNGPLPVCKV 932
+ W+ P P C +
Sbjct: 924 PQGNGVWSSPAPRCGI 939
Score = 82.4 bits (202), Expect = 2e-15
Identities = 123/568 (21%), Positives = 204/568 (35%), Gaps = 86/568 (15%)
Query: 392 SCNFPRRPDSGDVTVMD-LHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V V+ + G + C GY L G+ TCI + W ++ PIC
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVH 509
G T G +S TN F H+ ++ + +
Sbjct: 163 RIPCGLPPTITNGDFIS------TNRENF---------------HYGSVVTY-----RCN 196
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
G + E V + N ++ S A N C
Sbjct: 197 PGSGGRKVF-------ELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---------KCTP 240
Query: 570 PYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC 628
P ++NG + + + +++ +VEF C PG + +GP ++C + W P C +C
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALNK--WEPELPSCSRVC 297
Query: 629 GGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN----SDILTIY 684
V + + + G++ + G + R ++ + + +
Sbjct: 298 QPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVK 356
Query: 685 DGDEVMPHIL-GQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN-YIEVS 740
D+ M +L G+ L Q D Q A G + N + V
Sbjct: 357 SCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 416
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDP------GYDIVGSDTLTCQWDLS- 792
C P I NG T E+ G + Y CDP +D++G T+ C D
Sbjct: 417 EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQG 476
Query: 793 ---WSSDPPFCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSS 844
WSS P C + +C P ++ T P +GT+++Y C P + S
Sbjct: 477 NGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP---IGTSLKYECRPEYYGRPFS 533
Query: 845 LLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEG 904
+TC +W+S C + +C P P NG + + + G + + C G
Sbjct: 534 -ITCLD----NLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTG 584
Query: 905 FELMGEVTIRCIL-GQPSHWNGPLPVCK 931
L+G + CIL G +HW+ P+C+
Sbjct: 585 HRLIGHSSAECILSGNAAHWSTKPPICQ 612
Score = 82.4 bits (202), Expect = 2e-15
Identities = 91/375 (24%), Positives = 158/375 (42%), Gaps = 38/375 (10%)
Query: 587 GTIVEFTCDPGHSLEQGPAIIECINVRDPY-WNDTEPLC-RAMCGGELSAVAGVVLSPNW 644
G+ ++++C G+ L G + CI D W++ P+C R CG + G +S N
Sbjct: 124 GSQIKYSCTKGYRLI-GSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTN- 181
Query: 645 PEPYVEGEDCIWKIHVGEEKRIFLDI----QFLNLSNSDILTIYDG--------DEVMPH 692
E + G ++ + G R ++ SN D + I+ G ++ P
Sbjct: 182 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 241
Query: 693 ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFG----KGQGFIMNYIEV-SRNDSCSD 747
+ + S + L+S ++F P ++ G K Q E+ S + C
Sbjct: 242 NVENGILVSDNRSLFSLNE--VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 748 LPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYC 806
P++ + +T + G + Y C+PGYD+ G+ ++ C WS P CE + C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKSC 358
Query: 807 TDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCV 866
D + R++ L +G + + C+ GF L+GSS C + +W S +P C
Sbjct: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSVPVC- 416
Query: 867 SEESLACDNPGLPENGYQILYKRLYLP-GESLTFMC------YEGFELMGEVTIRCILGQ 919
E + C +P + NG P G+++ + C F+L+GE TIRC
Sbjct: 417 --EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDP 474
Query: 920 PSH--WNGPLPVCKV 932
+ W+ P P C +
Sbjct: 475 QGNGVWSSPAPRCGI 489
Score = 82.0 bits (201), Expect = 3e-15
Identities = 88/393 (22%), Positives = 162/393 (41%), Gaps = 41/393 (10%)
Query: 567 CYEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P ++NG + + + +++ +VEF C PG ++ GP ++C + W P C
Sbjct: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK-GPRRVKCQALNK--WEPELPSCS 1194
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFL-------NLSNS 678
+C + G +P+ + + G++ + G + R +
Sbjct: 1195 RVCQPPPEILHGEH-TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Query: 679 DILTIYDGDEVMPH--ILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNY 736
+ + D +PH +L G + + ++ S ++ G + N
Sbjct: 1254 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGM-RSLWNNS 1312
Query: 737 IEVSRNDSCSDLPEIQNGWKT-TSHTELVRGARITYQCDPG------YDIVGSDTLTCQW 789
+ V + C + P I NG T T ++ G I+Y CDP ++++G T+ C
Sbjct: 1313 VPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 790 DLS----WSSDPPFCE---KIMYCTDPGEVDHS--TRLISDPVLLVGTTIQYTCNPGFVL 840
D WSS P CE + +C P + + T I+D VGT++ Y C PG+
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFG 1432
Query: 841 EGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFM 900
+ S ++C +W+S +C +C P P NG + G ++ +
Sbjct: 1433 KMFS-ISCLE----NLVWSSVEDNC---RRKSCGPPPEPFNGMVHINTDTQF-GSTVNYS 1483
Query: 901 CYEGFELMGEVTIRCIL-GQPSHWNGPLPVCKV 932
C EGF L+G + C++ G W+ P+C++
Sbjct: 1484 CNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Score = 81.6 bits (200), Expect = 3e-15
Identities = 88/382 (23%), Positives = 150/382 (39%), Gaps = 51/382 (13%)
Query: 579 TSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC--------GG 630
T + + IGT + + C PG+S P I C+ ++ W + CR G
Sbjct: 58 TDEFEFPIGTYLNYECRPGYSGR--PFSIICL--KNSVWTGAKDRCRRKSCRNPPDPVNG 113
Query: 631 ELSAVAGV---------------VLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNL 675
+ + G+ ++ + + G+ IW RI +
Sbjct: 114 MVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIT 173
Query: 676 SNSDILTIYDGDEVMPHILGQYLGNSGPQKLYS--STPDLTIQFHSDPAGLIFGKGQGFI 733
+ I T + + + SG +K++ P + + D G+ G I
Sbjct: 174 NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 233
Query: 734 MNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDPGYDIVGSDTLTCQWDLS 792
+ + C+ P ++NG + + L + ++C PG+ + G + CQ
Sbjct: 234 IP-------NKCTP-PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
Query: 793 WSSDPPFCEKIMYCTDPGEVDHSTRLISD-PVLLVGTTIQYTCNPGFVLEGSSLLTCYSR 851
W + P C ++ C P +V H+ R D G + Y+C PG+ L G++ + C
Sbjct: 286 WEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC--- 340
Query: 852 ETGTPIWTSRLPHCVSEESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGE 910
T W+ P C E +CD+ G NG + L L G + F+C EGF+L G
Sbjct: 341 -TPQGDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGS 395
Query: 911 VTIRCIL-GQPSHWNGPLPVCK 931
C+L G S WN +PVC+
Sbjct: 396 SASYCVLAGMESLWNSSVPVCE 417
Score = 79.3 bits (194), Expect = 2e-14
Identities = 90/388 (23%), Positives = 158/388 (40%), Gaps = 62/388 (15%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECINV-RDPYWNDTEPLCRAM-CGGELSAVAGVVL-SP 642
+G V F CD G L+ G ++ C+ V WN++ P+C + C + + G +P
Sbjct: 1278 LGAKVSFVCDEGFRLK-GSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
Query: 643 NWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSG 702
+ PY G++ + ++ + ++ + S I D PH G + +
Sbjct: 1337 SGDIPY--GKEISYTCDPHPDRGMTFNL----IGESTIRCTSD-----PHGNGVWSSPAP 1385
Query: 703 -------------PQKLYSSTPDLTIQFHSDPAGL---------IFGKG------QGFIM 734
P++ ++P + I P G FGK + +
Sbjct: 1386 RCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVW 1445
Query: 735 NYIEVS-RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQW---D 790
+ +E + R SC PE NG +T+ G+ + Y C+ G+ ++GS + TC +
Sbjct: 1446 SSVEDNCRRKSCGPPPEPFNGM-VHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNN 1504
Query: 791 LSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL-VGTTIQYTCNPG------FVLEGS 843
++W P CE I+ C P + + ++ GT + Y C+ G F L G
Sbjct: 1505 VTWDKKAPICE-IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGE 1563
Query: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCY 902
+ C S++ +W+S P C+S C P + EN ++ R + E + F C
Sbjct: 1564 RSIYCTSKDDQVGVWSSPPPRCISTNK--CTAPEV-ENAIRVPGNRSFFTLTEIIRFRCQ 1620
Query: 903 EGFELMGEVTIRCILGQPSHWNGPLPVC 930
GF ++G T++C W LP C
Sbjct: 1621 PGFVMVGSHTVQCQTN--GRWGPKLPHC 1646
Score = 77.0 bits (188), Expect = 8e-14
Identities = 88/391 (22%), Positives = 151/391 (38%), Gaps = 42/391 (10%)
Query: 567 CYEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR 625
C P ++NG + + + +++ +VEF C PG + +GP ++C + W P C
Sbjct: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALNK--WEPELPSCS 744
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSN----SDIL 681
+C V + + + G++ + G + R ++ + +
Sbjct: 745 RVCQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Query: 682 TIYDGDEVMPHIL-GQYLGNSGPQ--KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN-YI 737
+ D+ M +L G+ L Q D Q A G + N +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDP------GYDIVGSDTLTCQWD 790
V C P I NG T E+ G + Y CDP +D++G T+ C D
Sbjct: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 791 LS----WSSDPPFCEKIMYCTDP-----GEVDHSTRLISDPVLLVGTTIQYTCNPGFVLE 841
WSS P C + +C P ++ T P +GT+++Y C P +
Sbjct: 924 PQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP---IGTSLKYECRPEYYGR 980
Query: 842 GSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMC 901
S +TC +W+S C + +C P P NG + + + G + + C
Sbjct: 981 PFS-ITCLD----NLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 1031
Query: 902 YEGFELMGEVTIRCIL-GQPSHWNGPLPVCK 931
G L+G + CIL G +HW+ P+C+
Sbjct: 1032 TTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Score = 76.3 bits (186), Expect = 1e-13
Identities = 55/203 (27%), Positives = 84/203 (41%), Gaps = 16/203 (7%)
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSWS 794
+V + SC P+ NG T++ G+RI Y C G+ ++G + C WS
Sbjct: 547 DVCKRKSCKTPPDPVNGMVHVI-TDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWS 605
Query: 795 SDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTC 848
+ PP C++I P + + G+ + Y CNPG F L G + C
Sbjct: 606 TKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 665
Query: 849 YSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKR-LYLPGESLTFMCYEGFEL 907
S + IW+ P C+ C P + ENG + R L+ E + F C GF +
Sbjct: 666 TSNDDQVGIWSGPAPQCIIPNK--CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVM 722
Query: 908 MGEVTIRCILGQPSHWNGPLPVC 930
G ++C + W LP C
Sbjct: 723 KGPRRVKC--QALNKWEPELPSC 743
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/186 (29%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 744 SCSD-LPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQ---WDLSWSSDPPF 799
SC D L ++ +G + L GA++++ CD G+ + G C W+S P
Sbjct: 1710 SCDDFLGQLPHG-RVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPV 1768
Query: 800 CEKIMYCTDPGEV---DHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTCYS 850
CE+I +C +P + H+ D + G I Y C+ F L G S + C S
Sbjct: 1769 CEQI-FCPNPPAILNGRHTGTPFGD--IPYGKEISYACDTHPDRGMTFNLIGESSIRCTS 1825
Query: 851 RETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI-LYKRLYLPGESLTFMCYEGFELMG 909
G +W+S P C AC +P +NG+ I + LYLPG +++++C G+ L+G
Sbjct: 1826 DPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVG 1885
Query: 910 EVTIRC 915
+ I C
Sbjct: 1886 KGFIFC 1891
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 16/203 (7%)
Query: 738 EVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSWS 794
+V + SC P+ NG T++ G+RI Y C G+ ++G + C WS
Sbjct: 997 DVCKRKSCKTPPDPVNGMVHVI-TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWS 1055
Query: 795 SDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSSLLTC 848
+ PP C++I P + + G+ + Y CN G F L G + C
Sbjct: 1056 TKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYC 1115
Query: 849 YSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKR-LYLPGESLTFMCYEGFEL 907
S + IW+ P C+ C P + ENG + R L+ E + F C GF +
Sbjct: 1116 TSNDDQVGIWSGPAPQCIIPNK--CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVM 1172
Query: 908 MGEVTIRCILGQPSHWNGPLPVC 930
G ++C + W LP C
Sbjct: 1173 KGPRRVKC--QALNKWEPELPSC 1193
Score = 67.0 bits (162), Expect = 9e-11
Identities = 56/183 (30%), Positives = 83/183 (45%), Gaps = 18/183 (9%)
Query: 758 TSHTELVRGARITYQCDPGYDIVGSD-TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHST 816
T+ ++ G + Y+C P Y G ++TC +L WSS C++ T P V+
Sbjct: 958 TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 1015
Query: 817 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
+I+D + VG+ I Y+C G L G S C T W+++ P C + + C P
Sbjct: 1016 HVITD--IQVGSRINYSCTTGHRLIGHSSAECI-LSGNTAHWSTKPPIC---QRIPCGLP 1069
Query: 877 GLPENGYQILYKR-LYLPGESLTFMCYEG------FELMGEVTIRCILG--QPSHWNGPL 927
NG I R + G +T+ C G FEL+GE +I C Q W+GP
Sbjct: 1070 PTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPA 1129
Query: 928 PVC 930
P C
Sbjct: 1130 PQC 1132
Score = 67.0 bits (162), Expect = 9e-11
Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 20/191 (10%)
Query: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
G + Y+C PGY +++C +L WSS C + P + + +D
Sbjct: 1419 GTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF- 1476
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENG-YQ 884
G+T+ Y+CN GF L GS TC W + P C E ++C+ P NG +
Sbjct: 1477 -GSTVNYSCNEGFRLIGSPSTTCLVSGNNV-TWDKKAPIC---EIISCEPPPTISNGDFY 1531
Query: 885 ILYKRLYLPGESLTFMCYEG------FELMGEVTIRCIL--GQPSHWNGPLPVC----KV 932
+ + G +T+ C+ G FEL+GE +I C Q W+ P P C K
Sbjct: 1532 SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKC 1591
Query: 933 NQDSFEHALEV 943
E+A+ V
Sbjct: 1592 TAPEVENAIRV 1602
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 758 TSHTELVRGARITYQCDPGYDIVGSD-TLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHST 816
T+ ++ G + Y+C P Y G ++TC +L WSS C++ T P V+
Sbjct: 508 TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 565
Query: 817 RLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNP 876
+I+D + VG+ I Y+C G L G S C W+++ P C + + C P
Sbjct: 566 HVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPIC---QRIPCGLP 619
Query: 877 GLPENGYQILYKR-LYLPGESLTFMCYEG------FELMGEVTIRCILG--QPSHWNGPL 927
NG I R + G +T+ C G FEL+GE +I C Q W+GP
Sbjct: 620 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 679
Query: 928 PVC 930
P C
Sbjct: 680 PQC 682
Score = 57.0 bits (136), Expect = 9e-08
Identities = 72/287 (25%), Positives = 108/287 (37%), Gaps = 55/287 (19%)
Query: 586 IGTIVEFTCDPGHSLEQGPAIIECINV-RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNW 644
+G V F CD G L+ G + C+ WN + P+C + PN
Sbjct: 1731 LGAKVSFVCDEGFRLK-GRSASHCVLAGMKALWNSSVPVCEQ------------IFCPN- 1776
Query: 645 PEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQ 704
P + G H G F DI + G E+ Y ++ P
Sbjct: 1777 PPAILNGR------HTGTP---FGDIPY-------------GKEI------SYACDTHPD 1808
Query: 705 K--LYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTE 762
+ ++ + +I+ SDP G E+S +C P+IQNG H
Sbjct: 1809 RGMTFNLIGESSIRCTSDPQGNGVWSSPA---PRCELSVPAACPHPPKIQNGHYIGGHVS 1865
Query: 763 L-VRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDH-STRLIS 820
L + G I+Y CDPGY +VG + C WS +C+++ C+ P ++ S L
Sbjct: 1866 LYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEV-NCSFPLFMNGISKELEM 1924
Query: 821 DPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVS 867
V G + C G+ LEGS C + + W L C S
Sbjct: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR----WDPPLAKCTS 1967
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
Query: 816 TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN 875
T L + +GT + Y C PG+ S++ C +WT C +C N
Sbjct: 55 TNLTDEFEFPIGTYLNYECRPGYSGRPFSII-CLKNS----VWTGAKDRC---RRKSCRN 106
Query: 876 PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPSHWNGPLPVC 930
P P NG + K + G + + C +G+ L+G + CI+ G W+ P+C
Sbjct: 107 PPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 392 SCNFPRRPDSGDVTVM-DLHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V V+ D+ G ++ C G+ L G CI + + HWS++ PIC
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 450 -APCG 453
PCG
Sbjct: 613 RIPCG 617
Score = 36.6 bits (83), Expect = 0.12
Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%)
Query: 392 SCNFPRRPDSGDVTV-MDLHSGGVAHFHCHLGYELQGAKMLTC-INASKPHWSSQEPICS 449
SC P P +G V + D G ++ C+ G+ L G+ TC ++ + W + PIC
Sbjct: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1515
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKL 491
+ G S + NG+ P+G++L
Sbjct: 1516 IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL 1557
Score = 32.0 bits (71), Expect = 3.1
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-PCGGAVHNATIGRVLSP 467
G + C GY+L+GA L C + WS + P C+ C + GRVL P
Sbjct: 1219 GQEVFYSCEPGYDLRGAASLHC--TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
Score = 30.8 bits (68), Expect = 6.8
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSA-PCGGAVHNATIGRVLSP 467
G + C GY+L+GA + C + WS P C C + GRVL P
Sbjct: 769 GQEVFYSCEPGYDLRGAASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 96.3 bits (238), Expect = 1e-19
Identities = 103/458 (22%), Positives = 184/458 (40%), Gaps = 62/458 (13%)
Query: 279 ALCSVSFSNPEGYIDSSDYPLLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGE----- 333
A+C G+I S +YP C + + V G+ V L +S + +
Sbjct: 433 AICGGDVKKDYGHIQSPNYPD-DYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 334 LLSIRGVDGPTLTVLANQTLLVEGQVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSC 393
L +R + T++ + I+S ++ + + F + F +++ + C
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDEC 551
Query: 394 NFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCG 453
+ RP+ G L++ G C GYEL K C A CG
Sbjct: 552 S---RPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRR----------------CEAACG 592
Query: 454 GAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDR-----MTV 508
G + G + SP +P+ ++ CIW + AP ++ L F+ D + V
Sbjct: 593 GFLTKLN-GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEV 651
Query: 509 HSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCY 568
SG T S L +E E + S+ N +R+EF SD + F F + +K C
Sbjct: 652 RSGLTADSKLHGKFCGSEKP--EVITSQYNNMRVEFKSDNTVSKKGFKAHFFS-DKDECS 708
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR-AM 627
+ NG D G+ E C G L +D + C+ A
Sbjct: 709 K---DNGG-CQQDCVNTFGSY-ECQCRSGFVL-----------------HDNKHDCKEAG 746
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
C ++++ +G + SPNWP+ Y ++C W I R+ L +++ + D L
Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
++DG + +LG++ G+ P+ + ++ + ++F+SD
Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSD 844
Score = 91.3 bits (225), Expect = 4e-18
Identities = 74/285 (25%), Positives = 123/285 (43%), Gaps = 37/285 (12%)
Query: 447 ICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL--HDK- 503
+ A CGG V G + SP+YP++ S+ CIW I+ EG + L F+ + HD
Sbjct: 430 VYEAICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSC 488
Query: 504 --DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEA 561
D + V G + S L+ E + + S + + ++F SD + + F + F
Sbjct: 489 AYDYLEVRDGHSESSTLIGRYCGYEKP--DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 562 FEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTE 621
E C P N +G+ + +CDPG+ L +
Sbjct: 547 -EVDECSRP---NRGGCEQRCLNTLGSY-KCSCDPGYELAPD-----------------K 584
Query: 622 PLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDIL 681
C A CGG L+ + G + SP WP+ Y ++CIW++ + RI L F +D+
Sbjct: 585 RRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC 644
Query: 682 TIYDGDEVMPHIL------GQYLGNSGPQKLYSSTPDLTIQFHSD 720
YD EV + G++ G+ P+ + S ++ ++F SD
Sbjct: 645 K-YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSD 688
Score = 61.6 bits (148), Expect = 4e-09
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 16/159 (10%)
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSD-----I 680
A+CGG++ G + SPN+P+ Y + CIW+I V E + L Q + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 681 LTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS 740
L + DG ++G+Y G P + S++ L ++F SD G I GF +N+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSD--GSI--NKAGFAVNFFK-- 546
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDI 779
D CS + G + L CDPGY++
Sbjct: 547 EVDECS--RPNRGGCEQRCLNTL---GSYKCSCDPGYEL 580
Score = 51.6 bits (122), Expect = 4e-06
Identities = 75/373 (20%), Positives = 134/373 (35%), Gaps = 93/373 (24%)
Query: 358 QVIRSPTNTISVYFRTFQDDGLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHF 417
+VI S N + V F++ F+ H+ + C+ D+G +++ G
Sbjct: 672 EVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECS----KDNGGCQQDCVNTFGSYEC 727
Query: 418 HCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQ 477
C G+ L K C A H + +T G + SP++P+ +
Sbjct: 728 QCRSGFVLHDNKH-DCKEAGCDHKVT---------------STSGTITSPNWPDKYPSKK 771
Query: 478 FCIWTIEAPEGQKLHLHFERLLLHDK-----DRMTVHSGQTNKSALLYDSLQTESVPFEG 532
C W I + G ++ L F + + + D + V G+ K+ +L ++ E
Sbjct: 772 ECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKP--EP 829
Query: 533 LLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEF 592
+L+ G+ + + F SD + +Q F S
Sbjct: 830 VLATGSRMFLRFYSDNS----------------------VQRKGFQAS------------ 855
Query: 593 TCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGE 652
H+ E G + + +D Y A G N+P G
Sbjct: 856 -----HATECGGQVRADVKTKDLY-------SHAQFGDN-----------NYPG----GV 888
Query: 653 DCIWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYDGDEVMPHILGQYLGNSGPQKLY 707
DC W I E + L Q + D + ++DG + LG+Y G+ P+++Y
Sbjct: 889 DCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVY 948
Query: 708 SSTPDLTIQFHSD 720
S+ + ++FHSD
Sbjct: 949 SAGDSVLVKFHSD 961
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
CG L G SP +P Y C+W+I V ++I L+ L+L S D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRN 742
+ DG + G++ G+ P+ + S+ L ++F S + G+GF Y +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV----GKGFFAVYEAICGG 437
Query: 743 DSCSDLPEIQN 753
D D IQ+
Sbjct: 438 DVKKDYGHIQS 448
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 10/133 (7%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRM 506
CG + ++T G SP YP + C+W I G+K+ L+F L L+ D +
Sbjct: 322 CGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V G K A L +P E ++S + + +EF S F +EA G
Sbjct: 381 EVRDGFWRK-APLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGD 438
Query: 567 CYEPY--IQNGNF 577
+ Y IQ+ N+
Sbjct: 439 VKKDYGHIQSPNY 451
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 91.7 bits (226), Expect = 3e-18
Identities = 99/387 (25%), Positives = 156/387 (40%), Gaps = 61/387 (15%)
Query: 579 TSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC-RAMCGGELSAVAG 637
T D + IGT + + C PG+S P I C+ ++ W + C R C V G
Sbjct: 50 TDDFEFPIGTYLNYECRPGYSGR--PFSIICL--KNSVWTSAKDKCKRKSCRNPPDPVNG 105
Query: 638 VV-----------LSPNWPEPY-----------VEGEDCIWKIHVGEEKRIFLDIQFLNL 675
+ + + P+ Y + G IW RI + +
Sbjct: 106 MAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLP-PTI 164
Query: 676 SNSDILTI-----YDGDEVMPHILGQYLGNSGPQKLYS--STPDLTIQFHSDPAGLIFGK 728
+N D +I + G V H LG+ G +K++ P + D G+ G
Sbjct: 165 ANGDFTSISREYFHYGSVVTYHC---NLGSRG-KKVFELVGEPSIYCTSKDDQVGIWSGP 220
Query: 729 GQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVR-GARITYQCDPGYDIVGSDTLTC 787
I+ + C+ P ++NG + + L + ++C PG+ + G + C
Sbjct: 221 APQCIIP-------NKCTP-PNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 788 QWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISD-PVLLVGTTIQYTCNPGFVLEGSSLL 846
Q W + P C ++ C P +V H+ R D G + Y+C PG+ L GS+ L
Sbjct: 273 QALNKWEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYL 330
Query: 847 TCYSRETGTPIWTSRLPHCVSEESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGF 905
C T W+ P C E +CD+ G NG+ + L L G + F+C EGF
Sbjct: 331 HC----TPQGDWSPAAPRC---EVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDEGF 382
Query: 906 ELMGEVTIRCIL-GQPSHWNGPLPVCK 931
+L G C+L G S WN +PVC+
Sbjct: 383 QLKGSSASYCVLAGMESLWNSSVPVCE 409
Score = 86.7 bits (213), Expect = 1e-16
Identities = 55/190 (28%), Positives = 92/190 (48%), Gaps = 10/190 (5%)
Query: 745 CSDLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
C P++ + +T + G + Y C+PGYD+ GS L C WS P CE +
Sbjct: 289 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCE-V 347
Query: 804 MYCTD-PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 862
C D G++ + ++ L +G + + C+ GF L+GSS C + +W S +
Sbjct: 348 KSCDDFLGQLPNG-HVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMES-LWNSSV 405
Query: 863 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPS 921
P C E +C+ P +P NG + +++ G + + C G L+G + CIL G +
Sbjct: 406 PVC---ERKSCETPPVPVNGMVHVITDIHV-GSRINYSCTTGHRLIGHSSAECILSGNTA 461
Query: 922 HWNGPLPVCK 931
HW+ P+C+
Sbjct: 462 HWSMKPPICQ 471
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/141 (28%), Positives = 61/141 (43%), Gaps = 16/141 (11%)
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWD---LSW 793
+ V SC P NG T++ G+RI Y C G+ ++G + C W
Sbjct: 405 VPVCERKSCETPPVPVNGMVHVI-TDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHW 463
Query: 794 SSDPPFCEKIMYCTDPGEV---DHSTRLISDPVLLVGTTIQYTCNPG------FVLEGSS 844
S PP C++I +C +P + H+ + D + G + YTC+P F L G S
Sbjct: 464 SMKPPICQQI-FCPNPPAILNGRHTGTPLGD--IPYGKEVSYTCDPHPDRGMTFNLIGES 520
Query: 845 LLTCYSRETGTPIWTSRLPHC 865
+ S G +W+S P C
Sbjct: 521 TIRRTSEPHGNGVWSSPAPRC 541
Score = 50.4 bits (119), Expect = 8e-06
Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Query: 816 TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDN 875
T L D +GT + Y C PG+ S++ C +WTS C + +C N
Sbjct: 47 TNLTDDFEFPIGTYLNYECRPGYSGRPFSII-CLKNS----VWTSAKDKC---KRKSCRN 98
Query: 876 PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCIL-GQPSHWNGPLPVC 930
P P NG + K + + + + C +G+ L+G + CI+ G W+ PVC
Sbjct: 99 PPDPVNGMAHVIKDIQFRSQ-IKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/240 (20%), Positives = 85/240 (35%), Gaps = 48/240 (20%)
Query: 392 SCNFPRRPDSGDVTVM-DLHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPICS 449
SC P P +G V+ D+ + C GY L G+ TCI + + W ++ P+C
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDKDRMTVH 509
R++ P NG I R H +T H
Sbjct: 155 -------------RIICGLPPTIANGDFTSI---------------SREYFHYGSVVTYH 186
Query: 510 SGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYE 569
++ +++ + S I TS + + C
Sbjct: 187 CNLGSRGKKVFELVGEPS--------------IYCTSKDDQVGIWSGPAPQCIIPNKCTP 232
Query: 570 PYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAMC 628
P ++NG + + + +++ +VEF C PG + +GP+ ++C + W P C +C
Sbjct: 233 PNVENGILVSDNRSLFSLNEVVEFRCQPGFGM-KGPSHVKCQALNK--WEPELPSCSRVC 289
Score = 40.8 bits (94), Expect = 0.007
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Query: 392 SCNFPRRPDSGDVTVM-DLHSGGVAHFHCHLGYELQGAKMLTCI-NASKPHWSSQEPIC 448
SC P P +G V V+ D+H G ++ C G+ L G CI + + HWS + PIC
Sbjct: 412 SCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Score = 31.6 bits (70), Expect = 4.0
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 407 MDLHSGGVAHFHCHLGYELQGAKMLTCINAS-KPHWSSQEPICS--------APCGGAVH 457
++L G F C G++L+G+ C+ A + W+S P+C P G VH
Sbjct: 366 LNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVH 425
Query: 458 NAT 460
T
Sbjct: 426 VIT 428
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 91.3 bits (225), Expect = 4e-18
Identities = 74/285 (25%), Positives = 123/285 (43%), Gaps = 37/285 (12%)
Query: 447 ICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL--HDK- 503
+ A CGG V G + SP+YP++ S+ CIW I+ EG + L F+ + HD
Sbjct: 430 VYEAICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSC 488
Query: 504 --DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEA 561
D + V G + S L+ E + + S + + ++F SD + + F + F
Sbjct: 489 AYDYLEVRDGHSESSTLIGRYCGYEKP--DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 562 FEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTE 621
E C P N +G+ + +CDPG+ L +
Sbjct: 547 -EVDECSRP---NRGGCEQRCLNTLGSY-KCSCDPGYELAPD-----------------K 584
Query: 622 PLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDIL 681
C A CGG L+ + G + SP WP+ Y ++CIW++ + RI L F +D+
Sbjct: 585 RRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC 644
Query: 682 TIYDGDEVMPHIL------GQYLGNSGPQKLYSSTPDLTIQFHSD 720
YD EV + G++ G+ P+ + S ++ ++F SD
Sbjct: 645 K-YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSD 688
Score = 61.6 bits (148), Expect = 4e-09
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 16/159 (10%)
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSD-----I 680
A+CGG++ G + SPN+P+ Y + CIW+I V E + L Q + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 681 LTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS 740
L + DG ++G+Y G P + S++ L ++F SD G I GF +N+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSD--GSI--NKAGFAVNFFK-- 546
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDI 779
D CS + G + L CDPGY++
Sbjct: 547 EVDECS--RPNRGGCEQRCLNTL---GSYKCSCDPGYEL 580
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
CG L G SP +P Y C+W+I V ++I L+ L+L S D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRN 742
+ DG + G++ G+ P+ + S+ L ++F S + G+GF Y +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV----GKGFFAVYEAICGG 437
Query: 743 DSCSDLPEIQN 753
D D IQ+
Sbjct: 438 DVKKDYGHIQS 448
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 10/133 (7%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRM 506
CG + ++T G SP YP + C+W I G+K+ L+F L L+ D +
Sbjct: 322 CGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V G K A L +P E ++S + + +EF S F +EA G
Sbjct: 381 EVRDGFWRK-APLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGD 438
Query: 567 CYEPY--IQNGNF 577
+ Y IQ+ N+
Sbjct: 439 VKKDYGHIQSPNY 451
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 91.3 bits (225), Expect = 4e-18
Identities = 74/285 (25%), Positives = 123/285 (43%), Gaps = 37/285 (12%)
Query: 447 ICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLL--HDK- 503
+ A CGG V G + SP+YP++ S+ CIW I+ EG + L F+ + HD
Sbjct: 430 VYEAICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSC 488
Query: 504 --DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEA 561
D + V G + S L+ E + + S + + ++F SD + + F + F
Sbjct: 489 AYDYLEVRDGHSESSTLIGRYCGYEKP--DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 562 FEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTE 621
E C P N +G+ + +CDPG+ L +
Sbjct: 547 -EVDECSRP---NRGGCEQRCLNTLGSY-KCSCDPGYELAPD-----------------K 584
Query: 622 PLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDIL 681
C A CGG L+ + G + SP WP+ Y ++CIW++ + RI L F +D+
Sbjct: 585 RRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC 644
Query: 682 TIYDGDEVMPHIL------GQYLGNSGPQKLYSSTPDLTIQFHSD 720
YD EV + G++ G+ P+ + S ++ ++F SD
Sbjct: 645 K-YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSD 688
Score = 61.6 bits (148), Expect = 4e-09
Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 16/159 (10%)
Query: 626 AMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSD-----I 680
A+CGG++ G + SPN+P+ Y + CIW+I V E + L Q + D
Sbjct: 433 AICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDY 492
Query: 681 LTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVS 740
L + DG ++G+Y G P + S++ L ++F SD G I GF +N+ +
Sbjct: 493 LEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSD--GSI--NKAGFAVNFFK-- 546
Query: 741 RNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDI 779
D CS + G + L CDPGY++
Sbjct: 547 EVDECS--RPNRGGCEQRCLNTL---GSYKCSCDPGYEL 580
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Query: 628 CGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILT 682
CG L G SP +P Y C+W+I V ++I L+ L+L S D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 683 IYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRN 742
+ DG + G++ G+ P+ + S+ L ++F S + G+GF Y +
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWV----GKGFFAVYEAICGG 437
Query: 743 DSCSDLPEIQN 753
D D IQ+
Sbjct: 438 DVKKDYGHIQS 448
Score = 41.6 bits (96), Expect = 0.004
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 10/133 (7%)
Query: 452 CGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLHDK-----DRM 506
CG + ++T G SP YP + C+W I G+K+ L+F L L+ D +
Sbjct: 322 CGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
V G K A L +P E ++S + + +EF S F +EA G
Sbjct: 381 EVRDGFWRK-APLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGD 438
Query: 567 CYEPY--IQNGNF 577
+ Y IQ+ N+
Sbjct: 439 VKKDYGHIQSPNY 451
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 89.0 bits (219), Expect = 2e-17
Identities = 99/394 (25%), Positives = 164/394 (41%), Gaps = 68/394 (17%)
Query: 458 NATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHF-----ERLLLHDKDRMTVHS-G 511
N G++ SP YP++ W I P+G ++ L+F E L + D + V +
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 512 QTNKSALLYDSLQTESVPF-EGLLSEGNTIRIEFTSDQARAA--STFNIRFEAFEKGHCY 568
Q + ++ TE P E +LS G+ + I F SD + + F+ + A + C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 569 EPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEP-LCRAM 627
E + E +CD G C R Y T+ CR
Sbjct: 145 EREDE-----------------ELSCDHYCHNYIGGYYCSC---RFGYILHTDNRTCRVE 184
Query: 628 CGGEL-SAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNSDILTIYDG 686
C L + GV+ SP++P PY + +C++ I + E+ +++QF DI I D
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIEL--EEGFMVNLQF-----EDIFDIEDH 237
Query: 687 DEVM-----------PHILGQYLGNSGPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMN 735
EV P +LG + G P+ + + + + I FHSD + G+ +G+ ++
Sbjct: 238 PEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNS----GENRGWRLS 293
Query: 736 YIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGY----DIVGSDT--LTCQW 789
Y + + C +L +G S + ++ CD GY D V DT + C
Sbjct: 294 Y--RAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLK 351
Query: 790 DLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPV 823
D +WS+ P C+K E+D + L S+ V
Sbjct: 352 DGTWSNKIPTCKK-------NEIDLESELKSEQV 378
Score = 56.6 bits (135), Expect = 1e-07
Identities = 81/367 (22%), Positives = 138/367 (37%), Gaps = 47/367 (12%)
Query: 282 SVSFSNPEGYIDSSDYP-LLPLNNFLECTYNVTVYTGYGVELQVKSVNLSDGEL-----L 335
+V +N G I S YP P ++ E T+N+TV G+ ++L NL L +
Sbjct: 21 TVELNNMFGQIQSPGYPDSYPSDS--EVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYV 78
Query: 336 SIRGVDGPTLTVLANQTLLVEG----QVIRSPTNTISVYFRT--FQDDGLGTFQLHYQAF 389
+ D T +T E +V+ SP + +S+ FR+ ++ F HY A
Sbjct: 79 KVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Query: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 449
+ R + + G + C GY L + C
Sbjct: 139 DVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILH----------------TDNRTCR 182
Query: 450 APCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLL---LHDKDRM 506
C + G + SP +P S C++TIE EG ++L FE + H +
Sbjct: 183 VECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPC 242
Query: 507 TVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEKGH 566
+ + E P E + ++ +++ I F SD + + + + A
Sbjct: 243 PYDYIKIKVGPKVLGPFCGEKAP-EPISTQSHSVLILFHSDNSGENRGWRLSYRA-AGNE 300
Query: 567 CYEPYIQ---NGNFTTSDPTYNIGTIVEFTCDPGH-----SLEQGPAIIECINVRDPYWN 618
C P +Q +G S Y V +CD G+ ++E IEC+ +D W+
Sbjct: 301 C--PELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECL--KDGTWS 356
Query: 619 DTEPLCR 625
+ P C+
Sbjct: 357 NKIPTCK 363
Score = 37.0 bits (84), Expect = 0.095
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 19/188 (10%)
Query: 631 ELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS-----DILTIYD 685
EL+ + G + SP +P+ Y + W I V + RI L NL +S D + +
Sbjct: 23 ELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVET 82
Query: 686 GDEVMPHILGQYLGNS----GPQKLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSR 741
D+V+ G+ ++ G + + S ++I F SD + + GF +Y+ V
Sbjct: 83 EDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSN--EERFTGFDAHYMAVD- 139
Query: 742 NDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
D C + + + H + C GY I+ +D TC+ + SD F +
Sbjct: 140 VDECKEREDEELSCDHYCHNYI---GGYYCSCRFGY-ILHTDNRTCRVE---CSDNLFTQ 192
Query: 802 KIMYCTDP 809
+ T P
Sbjct: 193 RTGVITSP 200
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 85.9 bits (211), Expect = 2e-16
Identities = 64/206 (31%), Positives = 97/206 (47%), Gaps = 21/206 (10%)
Query: 745 CSDLPEIQNGWKTTSHT-ELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
C LP I NG T+ + + G +TY C+ GY +VG + C WS+ PP CE+
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
Query: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
C G + ++ P+L VG T + C+ G+ L+G C G WT ++P
Sbjct: 214 R-CKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGV-AWT-KMP 269
Query: 864 HCVSEESLACDNPGLPENGYQI---LYKRLYLPGESLTFMC----YEG--FELMGEVTIR 914
C E + C +P NG I L Y G +T+ C EG F L+GE T+R
Sbjct: 270 VC---EEIFCPSPPPILNGRHIGNSLANVSY--GSIVTYTCDPDPEEGVNFILIGESTLR 324
Query: 915 CILG--QPSHWNGPLPVCKVNQDSFE 938
C + + W+GP P C+++ + +
Sbjct: 325 CTVDSQKTGTWSGPAPRCELSTSAVQ 350
Score = 79.3 bits (194), Expect = 2e-14
Identities = 55/174 (31%), Positives = 81/174 (46%), Gaps = 17/174 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEV---DHSTRLISDPVLL 825
+ C GY + GS CQ + W + C++I C P + H+ + D
Sbjct: 491 VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT-CPPPPVIYNGAHTGSSLED--FP 547
Query: 826 VGTTIQYTCNPG------FVLEGSSLLTCYSRETGTPIWTSRLPHC-VSEESLACDNPGL 878
GTT+ YTCNPG F L G S + C S + W+ P C +S ++ C + +
Sbjct: 548 YGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 607
Query: 879 PENGYQILYKRL-YLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
NGY+I K Y +++TF CY GF L G IRC + W+ +PVC+
Sbjct: 608 -ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC--KADNTWDPEIPVCE 658
Score = 79.0 bits (193), Expect = 2e-14
Identities = 132/570 (23%), Positives = 219/570 (38%), Gaps = 70/570 (12%)
Query: 409 LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPS 468
L G A+F C GY LQG C+ A + ++ P+C + GR + S
Sbjct: 232 LRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNS 291
Query: 469 YPENTNGSQFCIWTIEAPE-GQKLHLHFERLL--LHDKDRMTVHSGQTNKSALLYDSLQT 525
+ GS PE G L E L D + SG + L ++Q
Sbjct: 292 LANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQC 351
Query: 526 ESVPF-EGLLSEGNTIRIEFT---------------SDQAR--AASTFNIRFEAFEKGHC 567
G + G R + S Q R A T+ EK
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQ 411
Query: 568 YEPYIQNGNFTTSDPT-YNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCR- 625
P I NG ++ GT ++++C+PG+ L G I+C + + W P C+
Sbjct: 412 APPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-GEESIQCTS--EGVWTPPVPQCKV 468
Query: 626 AMCGGE----LSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRI--FLDIQFLN-LSNS 678
A C L+ + P+ EG ++ + I F++I+ ++
Sbjct: 469 AACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCP 528
Query: 679 DILTIYDGD------EVMPH-ILGQYLGNSGPQK--LYSSTPDLTIQFHSDPA--GLIFG 727
IY+G E P+ Y N GP++ +S + TI+ S+ G G
Sbjct: 529 PPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSG 588
Query: 728 KGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTS-HTELVRGARITYQCDPGYDIVGSDTLT 786
++ + V CS + I NG+K + +T++C G+ + GS +
Sbjct: 589 PAPLCKLSLLAVQ----CSHV-HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIR 643
Query: 787 CQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQY---TCNPGFVLEGS 843
C+ D +W + P CEK H + + + L G+ ++ +C G+ L G
Sbjct: 644 CKADNTWDPEIPVCEK-------ETCQHVRQSLQE--LPAGSRVELVNTSCQDGYQLTGH 694
Query: 844 SLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENG-YQILYKRLYLPGESLTFMCY 902
+ C E G IW ++P C + + C P + NG + + +L G +++ C
Sbjct: 695 AYQMCQDAENG--IWFKKIPLC---KVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECD 749
Query: 903 EGFELMGEVTIRCILGQPSH--WNGPLPVC 930
+GF L+GE ++C H W+GP P C
Sbjct: 750 QGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 77.8 bits (190), Expect = 5e-14
Identities = 113/442 (25%), Positives = 163/442 (36%), Gaps = 85/442 (19%)
Query: 534 LSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFT 593
LS G + T ++AR S F G EP P +G F
Sbjct: 198 LSSGKWSAVPPTCEEARCKS-----LGRFPNGKVKEP-----------PILRVGVTANFF 241
Query: 594 CDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM-------------CGGELSAVA--GV 638
CD G+ L QGP C+ P+C + G L+ V+ +
Sbjct: 242 CDEGYRL-QGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
Query: 639 VLSPNWPEPYVEGEDCIWKIHVGEEK-RIFLDIQFLN----------LSNSDILTIYDGD 687
V P+P E+ + I +GE R +D Q LS S + +
Sbjct: 301 VTYTCDPDP----EEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH--- 353
Query: 688 EVMPHIL-GQYLGNSGPQKLYSSTPDLTIQFHSDPAGL--IFGKGQGFIMNYIEVSRNDS 744
P IL G+ + + Y+ T F G I QG V +
Sbjct: 354 ---PQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE- 409
Query: 745 CSDLPEIQNGWKTTSHTELVR---GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
C P I NG K H +VR G I Y C+PGY +VG +++ C + W+ P C
Sbjct: 410 CQAPPNILNGQKEDRH--MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC- 466
Query: 802 KIMYCTDPGEVDHSTRLISDPV-LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS 860
K+ C G +L++ P V + +C G+ L GS C GT W
Sbjct: 467 KVAACEATGR-----QLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ----GTIPWFM 517
Query: 861 RLPHCVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCYEG------FELMGEVTI 913
+ C + + C P + NG P G ++T+ C G F L+GE TI
Sbjct: 518 EIRLC---KEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 914 RCILGQPSH--WNGPLPVCKVN 933
RC W+GP P+CK++
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLS 596
Score = 76.3 bits (186), Expect = 1e-13
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 18/190 (9%)
Query: 749 PEIQNGWKTT-SHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY-- 805
PE+++G+K +H+ + C+PG+ + GS + C D +W P C K +
Sbjct: 791 PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIG 850
Query: 806 CTDPGEVDHSTRLISDPV-LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPH 864
C P + + + G +I Y+C+ G++L G +LL C T W+ PH
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT----WSQPAPH 906
Query: 865 CVSEESLACDNPGLPENGYQ--ILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 922
C + + C +P +G Q + +++Y G +T C +G+ L G +C Q H
Sbjct: 907 C---KEVNCSSPA-DMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC---QSDH 959
Query: 923 -WNGPLPVCK 931
WN PL VC+
Sbjct: 960 QWNPPLAVCR 969
Score = 72.8 bits (177), Expect = 2e-12
Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 18/198 (9%)
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPF 799
SC P I NG + T + G I Y C + ++G +L C + D +W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 800 CE---KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
CE K C +P V ++ G ++ + C F + G+ + C + P
Sbjct: 82 CEYFNKYSSCPEP-IVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
Query: 857 IWTSRLPHCVSEESLACDNPGLP--ENGYQILYK-RLYLPGESLTFMCYEGFELMGEVTI 913
+RLP CVS L C P LP NG+ PG S+T+ C G+ L+GE I
Sbjct: 141 ---TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 914 RCILGQPSHWNGPLPVCK 931
C+ W+ P C+
Sbjct: 196 NCL--SSGKWSAVPPTCE 211
Score = 63.9 bits (154), Expect = 7e-10
Identities = 56/231 (24%), Positives = 91/231 (39%), Gaps = 36/231 (15%)
Query: 722 AGLIFGKGQGFIMNYIEVS--RNDSCSDLPEIQNGWKTTSHTE-LVRGARITYQCDPG-- 776
+G ++ + QG I ++E+ + +C P I NG T S E G +TY C+PG
Sbjct: 502 SGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPE 561
Query: 777 ----YDIVGSDTLTC----QWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLI---SDPVLL 825
+ ++G T+ C Q +WS P C+ + V + +
Sbjct: 562 RGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYF 621
Query: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQI 885
T+ + C GF L+GSS + C + T W +P C E C + +
Sbjct: 622 YNDTVTFKCYSGFTLKGSSQIRCKADNT----WDPEIPVCEKE---TCQH---------V 665
Query: 886 LYKRLYLPG----ESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCKV 932
LP E + C +G++L G C + W +P+CKV
Sbjct: 666 RQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 716
Score = 59.3 bits (142), Expect = 2e-08
Identities = 51/200 (25%), Positives = 82/200 (41%), Gaps = 16/200 (8%)
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLS--WS 794
I V ++C + + S ELV + C GY + G CQ + W
Sbjct: 654 IPVCEKETCQHVRQSLQELPAGSRVELVNTS-----CQDGYQLTGHAYQMCQDAENGIWF 708
Query: 795 SDPPFCEKIMYCTDPGEVDHS--TRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRE 852
P C K+++C P + + T ++++ L G + Y C+ GF L G L C S
Sbjct: 709 KKIPLC-KVIHCHPPPVIVNGKHTGMMAEN-FLYGNEVSYECDQGFYLLGEKKLQCRSDS 766
Query: 853 TGTPIWTSRLPHCV-SEESLACDNPGLPENGYQILYKRLYLPGESLTFM-CYEGFELMGE 910
G W+ P C+ S C NP + ++GY++ + ++ C GF + G
Sbjct: 767 KGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGS 825
Query: 911 VTIRCILGQPSHWNGPLPVC 930
IRC + W +P C
Sbjct: 826 RVIRC--HTDNTWVPGVPTC 843
Score = 56.2 bits (134), Expect = 2e-07
Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 745 CSDLPEIQNGWKTTSH-TELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
C P+ NG T + G I Y CD GY +VG L C + +WS P C+++
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 910
Query: 804 MYCTDPGEVDHSTR-LISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
C+ P ++D + L + G + C G++LEGS C S P
Sbjct: 911 -NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNP 963
Score = 33.5 bits (75), Expect = 1.1
Identities = 47/231 (20%), Positives = 81/231 (35%), Gaps = 38/231 (16%)
Query: 417 FHCHLGYELQGAKMLTCINASKPHWSSQEPIC-------------SAPCGGAVHNATIGR 463
F C+ G+ L+G+ + C + W + P+C P G V +
Sbjct: 628 FKCYSGFTLKGSSQIRC--KADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVE--LVNT 683
Query: 464 VLSPSYPENTNGSQFC------IWTIEAPEGQKLHLHFERLLLHDKDRMTVHSGQTNKSA 517
Y + Q C IW + P + +H H ++++ K H+G ++
Sbjct: 684 SCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGK-----HTGMMAENF 738
Query: 518 LLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIRFEAFEK---GHCYEPYIQN 574
L + + E LL E +++ SD S + C P +++
Sbjct: 739 LYGNEVSYECDQGFYLLGEK---KLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKH 795
Query: 575 G-NFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
G + Y+ IV C+PG + G +I C D W P C
Sbjct: 796 GYKLNKTHSAYSHNDIVYVDCNPGF-IMNGSRVIRCHT--DNTWVPGVPTC 843
Score = 33.1 bits (74), Expect = 1.4
Identities = 27/111 (24%), Positives = 45/111 (40%), Gaps = 11/111 (9%)
Query: 699 GNSGPQKLYSSTPDLTIQFHSDPAGLIFGKG------QGFIMNYIEVSRNDSCS---DLP 749
GN + +P ++I + D L+ G+ +G + +CS D+
Sbjct: 860 GNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMD 919
Query: 750 EIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
IQ G + + GA +T +C+ GY + GS CQ D W+ C
Sbjct: 920 GIQKGLEPRKMYQY--GAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 30.8 bits (68), Expect = 6.8
Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 417 FHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSP 467
+ C GY L G K++ C+++ K WS+ P C ++ G+V P
Sbjct: 181 YSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEP 229
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 85.9 bits (211), Expect = 2e-16
Identities = 64/206 (31%), Positives = 97/206 (47%), Gaps = 21/206 (10%)
Query: 745 CSDLPEIQNGWKTTSHT-ELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
C LP I NG T+ + + G +TY C+ GY +VG + C WS+ PP CE+
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEA 213
Query: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
C G + ++ P+L VG T + C+ G+ L+G C G WT ++P
Sbjct: 214 R-CKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGV-AWT-KMP 269
Query: 864 HCVSEESLACDNPGLPENGYQI---LYKRLYLPGESLTFMC----YEG--FELMGEVTIR 914
C E + C +P NG I L Y G +T+ C EG F L+GE T+R
Sbjct: 270 VC---EEIFCPSPPPILNGRHIGNSLANVSY--GSIVTYTCDPDPEEGVNFILIGESTLR 324
Query: 915 CILG--QPSHWNGPLPVCKVNQDSFE 938
C + + W+GP P C+++ + +
Sbjct: 325 CTVDSQKTGTWSGPAPRCELSTSAVQ 350
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/414 (24%), Positives = 171/414 (41%), Gaps = 58/414 (14%)
Query: 548 QARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNI-GTIVEFTCDPGHSLEQGPAI 606
+ +A +T++ EKG P + +G T + + + G V++TCDPG+ L G
Sbjct: 643 RCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLV-GNKS 701
Query: 607 IECINVRDPYWNDTEPLCRAMC------------GGELSAVA-----GVVLSPNWPEPYV 649
I C+ + W+ + P C C G + V G L+ + +
Sbjct: 702 IHCMPSGN--WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQ 759
Query: 650 EGEDCIW--KIHVGEEKRIFLDIQFLNLSNSDILT---IYDGDEVMPHILGQYLGNSGPQ 704
+ E+ IW KI + + +N ++ ++ +Y + G YL G +
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYL--LGEK 817
Query: 705 KLYSSTPDLTIQFHSDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTT-SHTEL 763
KL Q SD G G G + C + PE+++G+K +H+
Sbjct: 818 KL---------QCRSDSKG--HGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAY 865
Query: 764 VRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMY--CTDPGEVDHSTRLISD 821
+ C+PG+ + GS + C D +W P C K + C P + + +
Sbjct: 866 SHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGN 925
Query: 822 PV-LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPE 880
G +I Y+C+ G++L G +LL C T W+ PHC + + C +P
Sbjct: 926 IARFSPGMSILYSCDQGYLLVGEALLLCTHEGT----WSQPAPHC---KEVNCSSPA-DM 977
Query: 881 NGYQ--ILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH-WNGPLPVCK 931
+G Q + +++Y G +T C +G+ L G +C Q H WN PL VC+
Sbjct: 978 DGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC---QSDHQWNPPLAVCR 1028
Score = 79.3 bits (194), Expect = 2e-14
Identities = 55/174 (31%), Positives = 81/174 (46%), Gaps = 17/174 (9%)
Query: 769 ITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEV---DHSTRLISDPVLL 825
+ C GY + GS CQ + W + C++I C P + H+ + D
Sbjct: 491 VNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT-CPPPPVIYNGAHTGSSLED--FP 547
Query: 826 VGTTIQYTCNPG------FVLEGSSLLTCYSRETGTPIWTSRLPHC-VSEESLACDNPGL 878
GTT+ YTCNPG F L G S + C S + W+ P C +S ++ C + +
Sbjct: 548 YGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 607
Query: 879 PENGYQILYKRL-YLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
NGY+I K Y +++TF CY GF L G IRC + W+ +PVC+
Sbjct: 608 -ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC--KADNTWDPEIPVCE 658
Score = 77.8 bits (190), Expect = 5e-14
Identities = 113/442 (25%), Positives = 163/442 (36%), Gaps = 85/442 (19%)
Query: 534 LSEGNTIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFT 593
LS G + T ++AR S F G EP P +G F
Sbjct: 198 LSSGKWSAVPPTCEEARCKS-----LGRFPNGKVKEP-----------PILRVGVTANFF 241
Query: 594 CDPGHSLEQGPAIIECINVRDPYWNDTEPLCRAM-------------CGGELSAVA--GV 638
CD G+ L QGP C+ P+C + G L+ V+ +
Sbjct: 242 CDEGYRL-QGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSI 300
Query: 639 VLSPNWPEPYVEGEDCIWKIHVGEEK-RIFLDIQFLN----------LSNSDILTIYDGD 687
V P+P E+ + I +GE R +D Q LS S + +
Sbjct: 301 VTYTCDPDP----EEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH--- 353
Query: 688 EVMPHIL-GQYLGNSGPQKLYSSTPDLTIQFHSDPAGL--IFGKGQGFIMNYIEVSRNDS 744
P IL G+ + + Y+ T F G I QG V +
Sbjct: 354 ---PQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKE- 409
Query: 745 CSDLPEIQNGWKTTSHTELVR---GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCE 801
C P I NG K H +VR G I Y C+PGY +VG +++ C + W+ P C
Sbjct: 410 CQAPPNILNGQKEDRH--MVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC- 466
Query: 802 KIMYCTDPGEVDHSTRLISDPV-LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTS 860
K+ C G +L++ P V + +C G+ L GS C GT W
Sbjct: 467 KVAACEATGR-----QLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ----GTIPWFM 517
Query: 861 RLPHCVSEESLACDNPGLPENGYQILYKRLYLP-GESLTFMCYEG------FELMGEVTI 913
+ C + + C P + NG P G ++T+ C G F L+GE TI
Sbjct: 518 EIRLC---KEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTI 574
Query: 914 RCILGQPSH--WNGPLPVCKVN 933
RC W+GP P+CK++
Sbjct: 575 RCTSNDQERGTWSGPAPLCKLS 596
Score = 72.8 bits (177), Expect = 2e-12
Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 18/198 (9%)
Query: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTC----QWDLSWSSDPPF 799
SC P I NG + T + G I Y C + ++G +L C + D +W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 800 CE---KIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTP 856
CE K C +P V ++ G ++ + C F + G+ + C + P
Sbjct: 82 CEYFNKYSSCPEP-IVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGP 140
Query: 857 IWTSRLPHCVSEESLACDNPGLP--ENGYQILYK-RLYLPGESLTFMCYEGFELMGEVTI 913
+RLP CVS L C P LP NG+ PG S+T+ C G+ L+GE I
Sbjct: 141 ---TRLPTCVSVFPLEC--PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 914 RCILGQPSHWNGPLPVCK 931
C+ W+ P C+
Sbjct: 196 NCL--SSGKWSAVPPTCE 211
Score = 30.8 bits (68), Expect = 6.8
Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 417 FHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSP 467
+ C GY L G K++ C+++ K WS+ P C ++ G+V P
Sbjct: 181 YSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVKEP 229
Score = 30.4 bits (67), Expect = 8.9
Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 412 GGVAHFHCHLGYELQGAKMLTCINASKPH--WSSQEPIC 448
G + C G+ L G K L C + SK H WS P C
Sbjct: 800 GNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 838
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 85.5 bits (210), Expect = 2e-16
Identities = 54/169 (31%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Query: 766 GARITYQCDPGY--DIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPV 823
G + Y+C PGY + S LTC +L WS+ FC+K C +PGE+ + + +
Sbjct: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK-KSCPNPGEIRNGQIDVPGGI 180
Query: 824 LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGY 883
L G TI ++CN G+ L GS+ C + W+ LP C + C P +NG
Sbjct: 181 LF-GATISFSCNTGYKLFGSTSSFCLISGSSVQ-WSDPLPEC---REIYCPAPPQIDNGI 235
Query: 884 QILYKRLYLPGESLTFMCYEGFELMGEVTIRC-ILGQPSHWNGPLPVCK 931
+ Y +S+T+ C +GF ++GE +I C + W+GP P C+
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 68.6 bits (166), Expect = 3e-11
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 19/196 (9%)
Query: 745 CSDLPEIQNGWKTTS-HTELVRGARITYQCDPGY-DIVGS-DTLTCQWDLSWSSDPPFCE 801
C P++ N T ITY+C+ + I G D++ C WS FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 802 KIMYCTDPGEVDHSTR---LISDPVLLVGTTIQYTCNPGFVLEG--SSLLTCYSRETGTP 856
+ C P ++ ++ I+ VGT ++Y C PG+ E S LTC
Sbjct: 96 RS--CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK--- 150
Query: 857 IWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
W++ + C + +C NPG NG QI L G +++F C G++L G + C+
Sbjct: 151 -WSTAVEFC---KKKSCPNPGEIRNG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCL 205
Query: 917 L-GQPSHWNGPLPVCK 931
+ G W+ PLP C+
Sbjct: 206 ISGSSVQWSDPLPECR 221
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 85.5 bits (210), Expect = 2e-16
Identities = 54/169 (31%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Query: 766 GARITYQCDPGY--DIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPV 823
G + Y+C PGY + S LTC +L WS+ FC+K C +PGE+ + + +
Sbjct: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK-KSCPNPGEIRNGQIDVPGGI 180
Query: 824 LLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGY 883
L G TI ++CN G+ L GS+ C + W+ LP C + C P +NG
Sbjct: 181 LF-GATISFSCNTGYKLFGSTSSFCLISGSSVQ-WSDPLPEC---REIYCPAPPQIDNGI 235
Query: 884 QILYKRLYLPGESLTFMCYEGFELMGEVTIRC-ILGQPSHWNGPLPVCK 931
+ Y +S+T+ C +GF ++GE +I C + W+GP P C+
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 68.6 bits (166), Expect = 3e-11
Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 19/196 (9%)
Query: 745 CSDLPEIQNGWKTTS-HTELVRGARITYQCDPGY-DIVGS-DTLTCQWDLSWSSDPPFCE 801
C P++ N T ITY+C+ + I G D++ C WS FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 802 KIMYCTDPGEVDHSTR---LISDPVLLVGTTIQYTCNPGFVLEG--SSLLTCYSRETGTP 856
+ C P ++ ++ I+ VGT ++Y C PG+ E S LTC
Sbjct: 96 RS--CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK--- 150
Query: 857 IWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCI 916
W++ + C + +C NPG NG QI L G +++F C G++L G + C+
Sbjct: 151 -WSTAVEFC---KKKSCPNPGEIRNG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCL 205
Query: 917 L-GQPSHWNGPLPVCK 931
+ G W+ PLP C+
Sbjct: 206 ISGSSVQWSDPLPECR 221
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 84.0 bits (206), Expect = 7e-16
Identities = 61/216 (28%), Positives = 97/216 (44%), Gaps = 19/216 (8%)
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSS 795
+ S + C +LP + N E + G TY C GY +VG TL C W +
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 796 DPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGT 855
C ++ +C DP V + S + V I + CN ++L+GS+ C T
Sbjct: 72 TTTEC-RLGHCPDPVLV--NGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT-- 126
Query: 856 PIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC 915
W P C S + CD PG P +GY + G ++++ C + + L+G +C
Sbjct: 127 --WAPPFPICKSRD---CDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQC 179
Query: 916 ILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETS 951
+ G+ W+ LPVCK+ Q++ + E A A + S
Sbjct: 180 VDGE---WSSALPVCKLIQEAPKPECEKALLAFQES 212
Score = 37.7 bits (86), Expect = 0.056
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 565 GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
GHC +P + NG F++S P N+ + F C+ H + +G +C+ D W P+C
Sbjct: 79 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCN-DHYILKGSNRSQCL--EDHTWAPPFPIC 134
Query: 625 RA 626
++
Sbjct: 135 KS 136
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 84.0 bits (206), Expect = 7e-16
Identities = 61/216 (28%), Positives = 97/216 (44%), Gaps = 19/216 (8%)
Query: 737 IEVSRNDSCSDLPEIQNGWKTTSHTE-LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSS 795
+ S + C +LP + N E + G TY C GY +VG TL C W +
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILG---TYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 796 DPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGT 855
C ++ +C DP V + S + V I + CN ++L+GS+ C T
Sbjct: 72 TTTEC-RLGHCPDPVLV--NGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHT-- 126
Query: 856 PIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRC 915
W P C S + CD PG P +GY + G ++++ C + + L+G +C
Sbjct: 127 --WAPPFPICKSRD---CDPPGNPVHGY--FEGNNFTLGSTISYYCEDRYYLVGVQEQQC 179
Query: 916 ILGQPSHWNGPLPVCKVNQDSFEHALEVAEAAAETS 951
+ G+ W+ LPVCK+ Q++ + E A A + S
Sbjct: 180 VDGE---WSSALPVCKLIQEAPKPECEKALLAFQES 212
Score = 37.7 bits (86), Expect = 0.056
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 565 GHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
GHC +P + NG F++S P N+ + F C+ H + +G +C+ D W P+C
Sbjct: 79 GHCPDPVLVNGEFSSSGPV-NVSDKITFMCN-DHYILKGSNRSQCL--EDHTWAPPFPIC 134
Query: 625 RA 626
++
Sbjct: 135 KS 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,172,769
Number of Sequences: 37866
Number of extensions: 2514956
Number of successful extensions: 13514
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 491
Number of HSP's that attempted gapping in prelim test: 9619
Number of HSP's gapped (non-prelim): 2853
length of query: 1024
length of database: 18,247,518
effective HSP length: 112
effective length of query: 912
effective length of database: 14,006,526
effective search space: 12773951712
effective search space used: 12773951712
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.