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Search of human proteins with 31881630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa
[Homo sapiens]
(358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom... 711 0.0
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 261 7e-70
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s... 250 2e-66
gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens] 173 2e-43
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 133 3e-31
gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 133 3e-31
gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4 [... 133 3e-31
gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [H... 130 1e-30
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 130 2e-30
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 130 2e-30
gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [H... 130 2e-30
gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [H... 130 2e-30
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 130 2e-30
gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [H... 130 2e-30
gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens] 127 1e-29
gi|4507381 thromboxane A2 receptor [Homo sapiens] 114 2e-25
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 100 3e-21
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 80 2e-15
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens] 76 4e-14
gi|4504097 G protein-coupled receptor 39 [Homo sapiens] 59 9e-09
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 58 1e-08
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap... 58 1e-08
gi|9507143 G protein-coupled receptor 173 [Homo sapiens] 54 2e-07
gi|226342980 G protein-coupled receptor 85 [Homo sapiens] 53 4e-07
gi|226342978 G protein-coupled receptor 85 [Homo sapiens] 53 4e-07
gi|226342976 G protein-coupled receptor 85 [Homo sapiens] 53 4e-07
gi|153266936 G protein-coupled receptor 85 [Homo sapiens] 53 4e-07
gi|16876435 G protein-coupled receptor 101 [Homo sapiens] 53 5e-07
gi|4885329 free fatty acid receptor 3 [Homo sapiens] 53 5e-07
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 52 8e-07
>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
sapiens]
Length = 358
Score = 711 bits (1836), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR 60
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
Sbjct: 1 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR 60
Query: 61 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS 120
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
Sbjct: 61 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS 120
Query: 121 LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ 180
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
Sbjct: 121 LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ 180
Query: 181 YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS 240
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
Sbjct: 181 YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS 240
Query: 241 GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA 300
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
Sbjct: 241 GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA 300
Query: 301 LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL 358
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
Sbjct: 301 LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL 358
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 261 bits (667), Expect = 7e-70
Identities = 150/330 (45%), Positives = 200/330 (60%), Gaps = 21/330 (6%)
Query: 13 CETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSL-SLFHVLV 71
C+ + G S + V+FS G+LGNL+AL LLAR G CS L S+F++LV
Sbjct: 8 CQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLG--WCSRRPLRPLPSVFYMLV 65
Query: 72 TELVFTDLLGTCLISPVVLASYARNQTLVALAP--ESRACTYFAFAMTFFSLATMLMLFA 129
L TDLLG CL+SPVVLA+YA+N++L LAP ++ C FAF M+FF L++ L L A
Sbjct: 66 CGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLA 125
Query: 130 MALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFI 189
MALE +LS+GHP+FY+R ++ G V PV+ A SL FC+LP + +G++VQYCPGTWCFI
Sbjct: 126 MALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFI 185
Query: 190 RH-------GRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGR 242
+ Y LY++L+ LL+++ + CN + NL MHRR +R S
Sbjct: 186 QMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRH--PRSCTRDC 243
Query: 243 GGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEK------- 295
P A R EE DHL+LLA+MT+ F +CSLP AY KEK
Sbjct: 244 AEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEA 303
Query: 296 WDLQALRFLSINSIIDPWVFAILRPPVLRL 325
DL+ALRFLS+ SI+DPW+F I R PV R+
Sbjct: 304 EDLRALRFLSVISIVDPWIFIIFRSPVFRI 333
>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
Length = 386
Score = 250 bits (638), Expect = 2e-66
Identities = 149/331 (45%), Positives = 194/331 (58%), Gaps = 31/331 (9%)
Query: 10 SEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHV 69
++ C ++ PA S++MF AGV+GN +AL +L SA R + S F V
Sbjct: 2 ADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGIL----------SARRPARPSAFAV 51
Query: 70 LVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTFFSLATMLMLF 128
LVT L TDLLGT +SP V +YARN +L+ LA A C FAFAMTFF LA+ML+LF
Sbjct: 52 LVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILF 111
Query: 129 AMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCF 188
AMA+ER L++ HPY Y + LP IYA +LFC+LPLL GQ+ QYCPG+WCF
Sbjct: 112 AMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCF 171
Query: 189 IR-----HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRG 243
+R G A+ YA L+ LL+ ++ CN SV L+L RM+R+ +R + G
Sbjct: 172 LRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQ-------GSL 224
Query: 244 GPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTI--FAYMNETSSRKEKWDLQAL 301
GP R GE +E DHLILLA+MT+ AVCSLP TI F S E DL A
Sbjct: 225 GP-RPRTGE-----DEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAF 278
Query: 302 RFLSINSIIDPWVFAILRPPVLRLMRSVLCC 332
RF + N I+DPWVF + R V + ++ +CC
Sbjct: 279 RFYAFNPILDPWVFILFRKAVFQRLKLWVCC 309
>gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens]
Length = 488
Score = 173 bits (439), Expect = 2e-43
Identities = 121/362 (33%), Positives = 180/362 (49%), Gaps = 49/362 (13%)
Query: 27 ISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLIS 86
I +VMF GV+GNL+A+ +L C + + + F+ LV L TDLLGT L+S
Sbjct: 23 IPAVMFIFGVVGNLVAIVVL---------CKSRKEQKETTFYTLVCGLAVTDLLGTLLVS 73
Query: 87 PVVLASYARNQTLVALAPESRA-CTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQ 145
PV +A+Y + Q P + C Y F + FFSL+ + ++ AM++ERYL+I H YFY
Sbjct: 74 PVTIATYMKGQW-----PGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYS 128
Query: 146 RRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIR-----HGRTAYLQLY 200
V + L +YA ++LFC+LP + G P TWCFI AY +Y
Sbjct: 129 HYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMY 188
Query: 201 ATLLLLLIVSVLACNFSVILNLIRMHRR-SRRSRCG--------PSLGSGRGGPGA---- 247
A LI++ + CN V L+RMHR+ RR+ G + + RG P A
Sbjct: 189 AGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPAL 248
Query: 248 -------RRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMN---ETSSRKE--- 294
RRR R E +ILL ++ +CS+P + ++N + S +E
Sbjct: 249 PRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSK 308
Query: 295 KWDLQALRFLSINSIIDPWVFAILRPPVL-RLMRSVLC--CRISLRTQDATQTSCSTQSD 351
DLQA+R S+N I+DPW++ +LR VL + + + C CRI ++ + CS
Sbjct: 309 NPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQR 368
Query: 352 AS 353
S
Sbjct: 369 TS 370
>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 133 bits (334), Expect = 3e-31
Identities = 110/367 (29%), Positives = 162/367 (44%), Gaps = 60/367 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSC 346
+ K+K + L A+R S+N I+DPWV+ +LR +LR C+I T + +S
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKF-----CQIRYHTNNYASSST 372
Query: 347 STQSDAS 353
S S
Sbjct: 373 SLPCQCS 379
>gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 133 bits (334), Expect = 3e-31
Identities = 110/367 (29%), Positives = 162/367 (44%), Gaps = 60/367 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSC 346
+ K+K + L A+R S+N I+DPWV+ +LR +LR C+I T + +S
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKF-----CQIRYHTNNYASSST 372
Query: 347 STQSDAS 353
S S
Sbjct: 373 SLPCQCS 379
>gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4
[Homo sapiens]
Length = 390
Score = 133 bits (334), Expect = 3e-31
Identities = 110/367 (29%), Positives = 162/367 (44%), Gaps = 60/367 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSC 346
+ K+K + L A+R S+N I+DPWV+ +LR +LR C+I T + +S
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKF-----CQIRYHTNNYASSST 372
Query: 347 STQSDAS 353
S S
Sbjct: 373 SLPCQCS 379
>gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [Homo
sapiens]
Length = 418
Score = 130 bits (328), Expect = 1e-30
Identities = 111/370 (30%), Positives = 166/370 (44%), Gaps = 61/370 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSC 346
+ K+K + L A+R S+N I+DPWV+ +LR +LR C++ R + Q C
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKF-----CQMRKR-RLREQLIC 371
Query: 347 STQSDASKQA 356
S Q+ ++A
Sbjct: 372 SLQNSQIQRA 381
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
sapiens]
Length = 388
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [Homo
sapiens]
Length = 365
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [Homo
sapiens]
Length = 374
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [Homo
sapiens]
Length = 425
Score = 130 bits (327), Expect = 2e-30
Identities = 104/338 (30%), Positives = 153/338 (45%), Gaps = 55/338 (16%)
Query: 20 PPGESPAISSV-------MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
PPG SV M G +GN +A+ L++R +R + R+ S F + +
Sbjct: 40 PPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRR---ESKRKKS---FLLCIG 93
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
L TDL+G L +PVV+ Y Q + P R CT+F MT F L+++ + AMA+
Sbjct: 94 WLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAV 153
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER L+I P++Y + AVL ++ L F LP+L GQY PGTWCFI G
Sbjct: 154 ERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTG 213
Query: 193 RTA-------------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLG 239
R + +A L LL + +CN + I L+ SRC
Sbjct: 214 RGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALV--------SRC----- 260
Query: 240 SGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIF---AYMNETS------ 290
R A + + + L+ IM + +VC P I N+TS
Sbjct: 261 --RAKATASQSSAQWGRITTETAIQLMGIMCV-LSVCWSPLLIMMLKMIFNQTSVEHCKT 317
Query: 291 -SRKEK---WDLQALRFLSINSIIDPWVFAILRPPVLR 324
+ K+K + L A+R S+N I+DPWV+ +LR +LR
Sbjct: 318 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLR 355
>gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens]
Length = 402
Score = 127 bits (320), Expect = 1e-29
Identities = 109/349 (31%), Positives = 159/349 (45%), Gaps = 51/349 (14%)
Query: 20 PPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR---RSSLSLFHVLVTELVF 76
P G SPA+ + G + NL+ALALLA+ +AGR R S + F + V L+
Sbjct: 31 PSGASPALPIFSMTLGAVSNLLALALLAQ--------AAGRLRRRRSAATFLLFVASLLA 82
Query: 77 TDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYL 136
TDL G + +VL Y + AP AC + M FF L +L+ MA+ER +
Sbjct: 83 TDLAGHVIPGALVLRLYTAGR-----APAGGACHFLGGCMVFFGLCPLLLGCGMAVERCV 137
Query: 137 SIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG---- 192
+ P + RVS + L + AV+L LPL G+Y PGTWCFI G
Sbjct: 138 GVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGG 197
Query: 193 -RTAYLQ-LYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS------GRGG 244
R A L L+A+L L+ +++ L CN L L+R R R R P+ G G G
Sbjct: 198 WRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHG 257
Query: 245 P-------------------GARRRGE-RVSMAEETDHLILLAIMTITFAVCSLPFTI-- 282
P G+R G R + A + + + L + + +C P +
Sbjct: 258 PRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLV 317
Query: 283 -FAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVL 330
A +S+ ++ A+R S N I+DPWV+ +LR VLR + +L
Sbjct: 318 ALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLL 366
>gi|4507381 thromboxane A2 receptor [Homo sapiens]
Length = 343
Score = 114 bits (284), Expect = 2e-25
Identities = 98/331 (29%), Positives = 150/331 (45%), Gaps = 37/331 (11%)
Query: 24 SPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTC 83
SP ++ G+ NL+AL++LA G G + S F + LV TD LG
Sbjct: 27 SPWFAASFCVVGLASNLLALSVLA-------GARQGGSHTRSSFLTFLCGLVLTDFLGLL 79
Query: 84 LISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYF 143
+ +V++ +A A+ P R C + M FF L+ +L+ AMA ERYL I P+
Sbjct: 80 VTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFS 139
Query: 144 YQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATL 203
S+ A + +++A +L LPLL G+Y PG+WCF+ G + +
Sbjct: 140 RPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFG-- 197
Query: 204 LLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHL 263
LL ++ L+ S +LN + S + C + G+ R R V M +
Sbjct: 198 LLFSMLGGLSVGLSFLLNTV-----SVATLC--HVYHGQEAAQQRPRDSEVEMMAQ---- 246
Query: 264 ILLAIMTITFAVCSLPFTIF------------AYMNETSSRKEKWDLQALRFLSINSIID 311
LL IM + +VC LP +F + + S EK L LR + N I+D
Sbjct: 247 -LLGIMVVA-SVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILD 304
Query: 312 PWVFAILRPPVLRLMRSVLCCR---ISLRTQ 339
PWV+ + R VLR ++ L R +SL+ Q
Sbjct: 305 PWVYILFRRAVLRRLQPRLSTRPRSLSLQPQ 335
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 100 bits (248), Expect = 3e-21
Identities = 84/334 (25%), Positives = 145/334 (43%), Gaps = 42/334 (12%)
Query: 13 CETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
C+T L S S + + G+L N +A+A+L + ++ R+ S + F +L +
Sbjct: 22 CQTENRL----SVFFSVIFMTVGILSNSLAIAILMKAYQ------RFRQKSKASFLLLAS 71
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
LV TD G + + + YA ++ + + C+ F M F L +L+ MA+
Sbjct: 72 GLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAI 131
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER + + P F+ +++ +L + ++ LP+L + Y TWCF
Sbjct: 132 ERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTE 191
Query: 193 RTA------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPG 246
YL L++ L LL + L CN + L+R+ +S++ R G
Sbjct: 192 DIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG----------- 240
Query: 247 ARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTI----FAYMNETSSRKEKWDLQALR 302
R + M + LLAIM ++ +C PF + S + L ALR
Sbjct: 241 ---RSHHLEMV-----IQLLAIMCVS-CICWSPFLVTMANIGINGNHSLETCETTLFALR 291
Query: 303 FLSINSIIDPWVFAILRPPVLRLMRSVL--CCRI 334
+ N I+DPWV+ +LR VL+ + + CC +
Sbjct: 292 MATWNQILDPWVYILLRKAVLKNLYKLASQCCGV 325
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 80.5 bits (197), Expect = 2e-15
Identities = 58/231 (25%), Positives = 104/231 (45%), Gaps = 16/231 (6%)
Query: 13 CETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVT 72
C+T L S S + + G+L N +A+A+L + ++ R+ S + F +L +
Sbjct: 22 CQTENRL----SVFFSVIFMTVGILSNSLAIAILMKAYQ------RFRQKSKASFLLLAS 71
Query: 73 ELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMAL 132
LV TD G + + + YA ++ + + C+ F M F L +L+ MA+
Sbjct: 72 GLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAI 131
Query: 133 ERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG 192
ER + + P F+ +++ +L + ++ LP+L + Y TWCF
Sbjct: 132 ERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTE 191
Query: 193 RTA------YLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPS 237
YL L++ L LL + L CN + L+R+ +S++ R G S
Sbjct: 192 DIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRS 242
>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
Length = 371
Score = 76.3 bits (186), Expect = 4e-14
Identities = 100/370 (27%), Positives = 148/370 (40%), Gaps = 53/370 (14%)
Query: 5 SNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSL 64
SN SQ +TR L A+ S++F A L N + LA LARR GRR
Sbjct: 21 SNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARR---------GRRGHW 71
Query: 65 SLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATM 124
+ HV + L DL VL A T P++ C + A+
Sbjct: 72 APIHVFIGHLCLADLAVALF---QVLPQLAWKATDRFRGPDA-LCRAVKYLQMVGMYASS 127
Query: 125 LMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLL--------DYG 176
M+ AM L+R+ +I P R S + + V +A SLL SLP L + G
Sbjct: 128 YMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLL-SLPQLFIFAQRNVEGG 186
Query: 177 QYVQYCPGTW-CFIR-HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRC 234
V C W CF GR Y+ A L++ + L +L +H
Sbjct: 187 SGVTDC---WACFAEPWGRRTYVTWIA--LMVFVAPTLGIAACQVLIFREIHASLVP--- 238
Query: 235 GPSLGSGRGGPGARRRGERVSMAEETDHLI--------LLAIMTITFAVCSLPF---TIF 283
GPS PG RRRG R E H+ + ++ + + +C PF ++
Sbjct: 239 GPS-----ERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLW 293
Query: 284 AYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCR-----ISLRT 338
A + + + + + S+NS +PW++A V +RS+LCC SL
Sbjct: 294 AAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGP 353
Query: 339 QDATQTSCST 348
QD + T+ S+
Sbjct: 354 QDESCTTASS 363
>gi|4504097 G protein-coupled receptor 39 [Homo sapiens]
Length = 453
Score = 58.5 bits (140), Expect = 9e-09
Identities = 59/267 (22%), Positives = 110/267 (41%), Gaps = 44/267 (16%)
Query: 108 ACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRR------------VSRSGGLA 155
+C F S AT+L + ++ ERY++I HP+ Y+ V + L
Sbjct: 107 SCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALV 166
Query: 156 VLPVIYAVSL------------LFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQ--LYA 201
LP+++A+ L C+ + + + + C R Q ++
Sbjct: 167 ALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFG 226
Query: 202 TLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETD 261
++ L+V +L+ F + N++++ +S++ SL G P R+ S
Sbjct: 227 AFVVYLVV-LLSVAF-MCWNMMQVLMKSQKG----SLAGGTRPPQLRKSESEESRTARRQ 280
Query: 262 HLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALR-----------FLSINSII 310
+I L ++ +T AVC +P I M + K W R F ++S+I
Sbjct: 281 TIIFLRLIVVTLAVCWMPNQIRRIM-AAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVI 339
Query: 311 DPWVFAILRPPVLRLMRSVLCCRISLR 337
+P ++ + R+ VLCCR+SL+
Sbjct: 340 NPLLYTVSSQQFRRVFVQVLCCRLSLQ 366
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 37 LGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARN 96
LGNL+ + L ++ L+L + V L ++ L + L+ P V+ S R
Sbjct: 43 LGNLVIVVTLYKK-----------SYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRR 91
Query: 97 QTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAV 156
+ + + C + A S A+ML L +A++RY ++ +P Y +++ + +
Sbjct: 92 EWIFGVV----WCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMA 147
Query: 157 LPVIYAVSLLFCSLPL-----LDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSV 211
L I+ SL+ C PL +++ ++ C W G TA+ Q++ L L+ +
Sbjct: 148 LVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAW-HREPGYTAFWQIWCALFPFLV--M 204
Query: 212 LACNFSVILNLIRMHRRSRRSRCG 235
L C + I + R+ ++R+ CG
Sbjct: 205 LVC-YGFIFRVARV--KARKVHCG 225
>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
sapiens]
Length = 309
Score = 57.8 bits (138), Expect = 1e-08
Identities = 81/294 (27%), Positives = 113/294 (38%), Gaps = 45/294 (15%)
Query: 5 SNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSL 64
SN SQ +TR L A+ S++F A L N + LA LARR GRR
Sbjct: 21 SNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARR---------GRRGHW 71
Query: 65 SLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATM 124
+ HV + L DL VL A T P++ C + A+
Sbjct: 72 APIHVFIGHLCLADLAVALF---QVLPQLAWKATDRFRGPDA-LCRAVKYLQMVGMYASS 127
Query: 125 LMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLL--------DYG 176
M+ AM L+R+ +I P R S + + V +A SLL SLP L + G
Sbjct: 128 YMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLL-SLPQLFIFAQRNVEGG 186
Query: 177 QYVQYCPGTW-CFIR-HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRC 234
V C W CF GR Y+ A L++ + L +L +H
Sbjct: 187 SGVTDC---WACFAEPWGRRTYVTWIA--LMVFVAPTLGIAACQVLIFREIHASLVP--- 238
Query: 235 GPSLGSGRGGPGARRRGERVSMAEETDHLI--------LLAIMTITFAVCSLPF 280
GPS PG RRRG R E H+ + ++ + + +C PF
Sbjct: 239 GPS-----ERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPF 287
>gi|9507143 G protein-coupled receptor 173 [Homo sapiens]
Length = 373
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/169 (26%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 68 HVLVTELVFTDLLGTCLISPVVLAS--YARNQTLVALAPESRACTYFAFAMTFFSLATML 125
+ + +L D + + + P VLAS + + T AL+ C AF F
Sbjct: 58 YYFLLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALS-----CKIVAFMAVLFCFHAAF 112
Query: 126 MLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGT 185
MLF +++ RY++I H FY +R++ AV+ + + +S+ P+ D G Y
Sbjct: 113 MLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREED 172
Query: 186 WCFIRHGRTAYLQLYATLLLLLIVSVL-ACNFSVILNLIRMHRRSRRSR 233
C H Y + TL +L+++VL A +V L+ R R+ +
Sbjct: 173 QCIFEH---RYFKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMK 218
>gi|226342980 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 53.1 bits (126), Expect = 4e-07
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 4/163 (2%)
Query: 68 HVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLML 127
+ + +L +D+L + + P V S T + C AF T ML
Sbjct: 56 YYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFML 112
Query: 128 FAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWC 187
F +++ RYL+I H FY +R++ LAV+ +++ +S+ P+LD G Y C
Sbjct: 113 FCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQC 172
Query: 188 FIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSR 230
+H R+ +LLL + +LA + + +H R +
Sbjct: 173 TFQH-RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRK 214
>gi|226342978 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 53.1 bits (126), Expect = 4e-07
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 4/163 (2%)
Query: 68 HVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLML 127
+ + +L +D+L + + P V S T + C AF T ML
Sbjct: 56 YYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFML 112
Query: 128 FAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWC 187
F +++ RYL+I H FY +R++ LAV+ +++ +S+ P+LD G Y C
Sbjct: 113 FCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQC 172
Query: 188 FIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSR 230
+H R+ +LLL + +LA + + +H R +
Sbjct: 173 TFQH-RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRK 214
>gi|226342976 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 53.1 bits (126), Expect = 4e-07
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 4/163 (2%)
Query: 68 HVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLML 127
+ + +L +D+L + + P V S T + C AF T ML
Sbjct: 56 YYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFML 112
Query: 128 FAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWC 187
F +++ RYL+I H FY +R++ LAV+ +++ +S+ P+LD G Y C
Sbjct: 113 FCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQC 172
Query: 188 FIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSR 230
+H R+ +LLL + +LA + + +H R +
Sbjct: 173 TFQH-RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRK 214
>gi|153266936 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 53.1 bits (126), Expect = 4e-07
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 4/163 (2%)
Query: 68 HVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLML 127
+ + +L +D+L + + P V S T + C AF T ML
Sbjct: 56 YYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY---GTLTCKVIAFLGVLSCFHTAFML 112
Query: 128 FAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWC 187
F +++ RYL+I H FY +R++ LAV+ +++ +S+ P+LD G Y C
Sbjct: 113 FCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQC 172
Query: 188 FIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSR 230
+H R+ +LLL + +LA + + +H R +
Sbjct: 173 TFQH-RSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRK 214
>gi|16876435 G protein-coupled receptor 101 [Homo sapiens]
Length = 508
Score = 52.8 bits (125), Expect = 5e-07
Identities = 50/232 (21%), Positives = 103/232 (44%), Gaps = 15/232 (6%)
Query: 1 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR 60
M + +S E + +P + P + + G++ + + + LA + G++ +
Sbjct: 1 MTSTCTNSTRESNSSHTCMPLSKMP----ISLAHGIIRSTVLVIFLAASFVGNIVLALVL 56
Query: 61 RSSLSLFHV---LVTELVFTDLLGTCLISPVVLASYARNQTLVALAP-ESRACTYFAFAM 116
+ L V + L+ TDLL L++P V+A+ ++ P S CT
Sbjct: 57 QRKPQLLQVTNRFIFNLLVTDLLQISLVAPWVVAT-----SVPLFWPLNSHFCTALVSLT 111
Query: 117 TFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYG 176
F+ A++ + ++++RYLSI HP Y ++++ G +L + V++L + PL +G
Sbjct: 112 HLFAFASVNTIVVVSVDRYLSIIHPLSYPSKMTQRRGYLLLYGTWIVAILQSTPPLYGWG 171
Query: 177 QYVQYCPGTWCFIRHGRTAYLQLYATLLLLLI--VSVLACNFSVILNLIRMH 226
Q C + G + + + + ++I + ++AC V R H
Sbjct: 172 QAAFDERNALCSMIWGASPSYTILSVVSFIVIPLIVMIACYSVVFCAARRQH 223
>gi|4885329 free fatty acid receptor 3 [Homo sapiens]
Length = 346
Score = 52.8 bits (125), Expect = 5e-07
Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 112 FAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLP 171
F F T + T L L A+++ER+LS+ HP +Y+ R V + ++ CS+
Sbjct: 93 FIFFTTIY--LTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVV 150
Query: 172 -LLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSR 230
++++ + + GT T YL+ L +L+ + +V+L ++ +
Sbjct: 151 YVIEFSGDISHSQGT------NGTCYLEFRKDQLAILL--PVRLEMAVVLFVVPL---II 199
Query: 231 RSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETS 290
S C L G G+ RR RV+ LLA + F VC P+ + +
Sbjct: 200 TSYCYSRLVWILGRGGSHRRQRRVAG--------LLAATLLNFLVCFGPYNVSHVVGYIC 251
Query: 291 SRKEKWDLQALRFLSINSIIDPWVF 315
W + ++NS +DP+V+
Sbjct: 252 GESPAWRIYVTLLSTLNSCVDPFVY 276
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 52.0 bits (123), Expect = 8e-07
Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 10/241 (4%)
Query: 35 GVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYA 94
G+LGNL + R V RS + ++ + L +D L + +PV S
Sbjct: 84 GMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSL 143
Query: 95 RNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGL 154
Q L C ++AF F +++M+ L A+AL+RYL I P S+
Sbjct: 144 YKQWLFG----ETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAA 199
Query: 155 AVLPVIYAVSLLFCSLPLLDYGQYV-----QYCPGTWCFIRHGRTAYLQLYATLLLLLIV 209
VL ++ +L + P + YV C + AY L + L +
Sbjct: 200 FVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPL 259
Query: 210 SVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIM 269
++ + I IR R+ ++ G G+G +R MA+ +ILL ++
Sbjct: 260 LIIIYCYIFIFRAIRETGRALQT-FGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVL 318
Query: 270 T 270
+
Sbjct: 319 S 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,804,160
Number of Sequences: 37866
Number of extensions: 506457
Number of successful extensions: 2686
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 2406
Number of HSP's gapped (non-prelim): 439
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.