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Search of human proteins with 31542656
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 954 0.0
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 369 e-102
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 311 8e-85
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 253 3e-67
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 221 1e-57
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 221 1e-57
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 218 1e-56
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 210 2e-54
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 205 8e-53
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 205 8e-53
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 201 2e-51
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 199 6e-51
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 199 6e-51
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 196 4e-50
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 195 7e-50
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 193 3e-49
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 191 1e-48
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ... 191 1e-48
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 191 2e-48
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 187 2e-47
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 187 2e-47
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 186 5e-47
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 185 9e-47
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 185 9e-47
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 185 9e-47
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 182 5e-46
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 182 8e-46
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 180 2e-45
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 178 9e-45
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 178 9e-45
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 954 bits (2466), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPI 60
MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPI
Sbjct: 1 MAGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPI 60
Query: 61 LQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
LQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK
Sbjct: 61 LQKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
Query: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR
Sbjct: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
Query: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQ 240
QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQ
Sbjct: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQ 240
Query: 241 RFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYR 300
RFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYR
Sbjct: 241 RFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYR 300
Query: 301 ILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLV 360
ILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLV
Sbjct: 301 ILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLV 360
Query: 361 HAIEEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEG 420
HAIEEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEG
Sbjct: 361 HAIEEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEG 420
Query: 421 KDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQ 480
KDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQ
Sbjct: 421 KDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRTPSGSHSGPVPSQ 480
Query: 481 GLV 483
GLV
Sbjct: 481 GLV 483
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 369 bits (947), Expect = e-102
Identities = 195/439 (44%), Positives = 275/439 (62%), Gaps = 9/439 (2%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F +LG++ L E C QLG +PT +Q+ IP L+GRD +G A+TGSGKT AF LPIL
Sbjct: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
Query: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
L E P +F LVLTPTRELA+QI+EQF LG +G++ +IVGG+D ++Q+L L++KPH+
Sbjct: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHI 145
Query: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183
+IATPGRL DHL ++ F+++ +++LVMDEADR+L DF +++ IL +P R+T
Sbjct: 146 IIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM---DFETEVDKILKVIPRDRKTF 202
Query: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
LFSAT+T +++LQ A P + TVE+L Q Y+ +P K KD YLV+++
Sbjct: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELA 262
Query: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
S +IF +TC Q ++LR F + LH M Q +R +L KFK+ IL+
Sbjct: 263 GN----SFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
Query: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363
ATDVASRGLDIP V VV+N + P K YIHRVGRTARAGR G+AIT VTQYD+ L I
Sbjct: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378
Query: 364 EEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDP 423
E I KKL F ++ EV+ + +V +R ++E EKK+ ++ + +
Sbjct: 379 EHLIGKKLPGFPTQDDEVMMLTERVAEAQRFA--RMELREHGEKKKRSREDAGDNDDTEG 436
Query: 424 DLEAKRKAELAKIKQKNRR 442
+ + K K+K++ R
Sbjct: 437 AIGVRNKVAGGKMKKRKGR 455
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 311 bits (797), Expect = 8e-85
Identities = 178/439 (40%), Positives = 249/439 (56%), Gaps = 58/439 (13%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F +LG++ L E C QLG +PT +Q+ IP L+GRD +G A+TGSGKT AF LPIL
Sbjct: 26 FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85
Query: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
L E P +F LVLTPTRELA+QI+EQF LG +G++ +IVGG+D ++Q+L L++KPH+
Sbjct: 86 LLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHI 145
Query: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183
+IATPGRL DHL ++ F+++ +++LVMDEADR+L DF +++ IL +P R+T
Sbjct: 146 IIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNM---DFETEVDKILKVIPRDRKTF 202
Query: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
LFSAT+T +++LQ A P + TVE+L Q Y+ +P K K L
Sbjct: 203 LFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKSKRL-------- 254
Query: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
+L KFK+ IL+
Sbjct: 255 ---------------------------------------------GSLNKFKAKARSILL 269
Query: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363
ATDVASRGLDIP V VV+N + P K YIHRVGRTARAGR G+AIT VTQYD+ L I
Sbjct: 270 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 329
Query: 364 EEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDP 423
E I KKL F ++ EV+ + +V +R ++E EKK+ ++ + +
Sbjct: 330 EHLIGKKLPGFPTQDDEVMMLTERVAEAQRFA--RMELREHGEKKKRSREDAGDNDDTEG 387
Query: 424 DLEAKRKAELAKIKQKNRR 442
+ + K K+K++ R
Sbjct: 388 AIGVRNKVAGGKMKKRKGR 406
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 253 bits (646), Expect = 3e-67
Identities = 159/472 (33%), Positives = 256/472 (54%), Gaps = 21/472 (4%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F ++ LS L++ +G KQPTP+Q CIP L G+D CA TG+GKTAAF LP+L++
Sbjct: 220 FQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLER 279
Query: 64 LSEDPYGI---FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
L P LVL PTREL Q+ R L + + C+ VGG+D+ +Q L
Sbjct: 280 LIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAA 339
Query: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
P ++IATPGRL DHL + +F + I L++DEADR+L++ F ++ I+ R
Sbjct: 340 PDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIRMCSHHR 396
Query: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVP---EKVKDAYLVH 237
QT+LFSAT+TD +++L ++ P + L Q ++ + E ++A +
Sbjct: 397 QTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAA 456
Query: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
L+ R +H +++FT T K + ++L LH + Q +R AL +FK
Sbjct: 457 LLTRTFTDH----VMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
IL+ATDVA+RGLDI V+ VIN P K Y+HRVGRTARAGR G++++LV + +
Sbjct: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDER 572
Query: 358 HLVHAIEEQIKKKLEEFSVEEAEVLQILTQVNVVRRE--CEIKLEAAHFD---EKKEINK 412
++ I + K ++ + + +L+ ++ + ++ ++LEA + + +IN
Sbjct: 573 KMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINT 632
Query: 413 RKQLILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGR 464
K+L+ +GK+ ++ + E + + K R KEK+ + L+ G K R
Sbjct: 633 AKRLLEKGKEAVVQ---EPERSWFQTKEERKKEKIAKALQEFDLALRGKKKR 681
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 221 bits (562), Expect = 1e-57
Identities = 140/360 (38%), Positives = 194/360 (53%), Gaps = 14/360 (3%)
Query: 3 GFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQ 62
GF +GLS + + + G K PTP+Q IP IL+G+D + A+TGSGKTA F+LP+ +
Sbjct: 97 GFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156
Query: 63 KLSEDPY--GIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
+L G L+L+PTRELA Q + + LGK GLK +I+GG M Q L
Sbjct: 157 RLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHEN 216
Query: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
P ++IATPGRL H+ + ++ + ++V DEADRL E G F L+ I+A +P
Sbjct: 217 PDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMG---FAEQLQEIIARLPGGH 272
Query: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQ 240
QT+LFSATL L E +P EQL + LV E K A L+HL+
Sbjct: 273 QTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLH 332
Query: 241 ---RFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
R QD+ ++F T + L +L ++S + R LAKF
Sbjct: 333 NVVRPQDQ-----TVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
LI TD+A+RGLDIP + VIN++ P K+++HRVGR ARAGR G A +LV +I
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 221 bits (562), Expect = 1e-57
Identities = 140/360 (38%), Positives = 194/360 (53%), Gaps = 14/360 (3%)
Query: 3 GFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQ 62
GF +GLS + + + G K PTP+Q IP IL+G+D + A+TGSGKTA F+LP+ +
Sbjct: 97 GFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156
Query: 63 KLSEDPY--GIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
+L G L+L+PTRELA Q + + LGK GLK +I+GG M Q L
Sbjct: 157 RLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHEN 216
Query: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
P ++IATPGRL H+ + ++ + ++V DEADRL E G F L+ I+A +P
Sbjct: 217 PDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMG---FAEQLQEIIARLPGGH 272
Query: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQ 240
QT+LFSATL L E +P EQL + LV E K A L+HL+
Sbjct: 273 QTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLH 332
Query: 241 ---RFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
R QD+ ++F T + L +L ++S + R LAKF
Sbjct: 333 NVVRPQDQ-----TVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLG 387
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
LI TD+A+RGLDIP + VIN++ P K+++HRVGR ARAGR G A +LV +I
Sbjct: 388 KCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEI 447
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 218 bits (554), Expect = 1e-56
Identities = 141/480 (29%), Positives = 250/480 (52%), Gaps = 30/480 (6%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL-- 61
+ + G+S ++ ++ G ++PTP+Q IPAI+ GRD +G AKTGSGKT AF+LP+
Sbjct: 374 WVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRH 433
Query: 62 ---QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELS 118
Q+ E+ G +++TPTRELA QI ++ + K LGL+ + GG + Q EL
Sbjct: 434 IMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELK 493
Query: 119 RKPHVVIATPGRLADHL--RSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176
R +++ TPGR+ D L S +++++ ++V+DEADR+ + G F + I+ V
Sbjct: 494 RGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMG---FEPQVMRIVDNV 550
Query: 177 PARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLV 236
RQT++FSAT + L ++P + ++Q+ +++ E+ K L+
Sbjct: 551 RPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLL 610
Query: 237 HLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKS 296
L+ +Q E S+IIF + + L L + S+P ++LH + Q +R + + FK+
Sbjct: 611 ELLGHYQ---ESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKN 667
Query: 297 SIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-- 354
++L+AT VA+RGLD+ + +V+N++ P + Y+HR GRT RAG +G A T +T+
Sbjct: 668 GTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQ 727
Query: 355 --YDIHLVHAIE---EQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKE 409
Y ++ A+E + LE+ + + Q + ++++ + FDE ++
Sbjct: 728 ARYAGDIIKALELSGTAVPPDLEKLWSDFKD--QQKAEGKIIKKSSGFSGKGFKFDETEQ 785
Query: 410 --INKRKQL------ILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGH 461
N+RK+L + + D D ++ + +R K+ A AG+
Sbjct: 786 ALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGN 845
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 210 bits (535), Expect = 2e-54
Identities = 131/390 (33%), Positives = 205/390 (52%), Gaps = 43/390 (11%)
Query: 13 LVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL---------QK 63
++E + G K+PTP+Q IP L+ RD +G A+TGSGKTAAF++P+L +
Sbjct: 402 ILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDR 461
Query: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
+ E G + ++L PTRELA QI E+ GKPLG++ ++GG+ Q L +
Sbjct: 462 IEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEI 521
Query: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR---- 179
VIATPGRL D L + + + ++V+DEADR+++ G F D++ IL +P
Sbjct: 522 VIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMIDMG---FEPDVQKILEHMPVSNQKP 577
Query: 180 ----------------------RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVE 217
RQT++F+AT+ + L +P + E
Sbjct: 578 DTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHE 637
Query: 218 QLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVA 277
+++Q+ L+ E K L+ ++++ D IIIF N K C +L L K +
Sbjct: 638 RVEQKVFLMSESEKRKKLLAILEQGFDP----PIIIFVNQKKGCDVLAKSLEKMGYNACT 693
Query: 278 LHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVG 337
LH Q++R AL+ K+ IL+ATDVA RG+DI V +V+N++ + YIHR+G
Sbjct: 694 LHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIG 753
Query: 338 RTARAGRQGQAITLVTQYDIHLVHAIEEQI 367
RT RAG+ G AIT +T+ D + + +++ I
Sbjct: 754 RTGRAGKSGVAITFLTKEDSAVFYELKQAI 783
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 205 bits (521), Expect = 8e-53
Identities = 132/352 (37%), Positives = 190/352 (53%), Gaps = 15/352 (4%)
Query: 24 QPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY-----GIFCLVLTP 78
+PTP+Q P L GRD +G A+TGSGKT A++LP + ++ PY G CLVL P
Sbjct: 193 EPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAP 252
Query: 79 TRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS 138
TRELA Q+ + GK LK I GG Q +L R + IATPGRL D L S
Sbjct: 253 TRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG 312
Query: 139 NTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTLREL-Q 197
T ++++ +LV+DEADR+L+ G F + I+ + RQTL++SAT +R+L +
Sbjct: 313 KT-NLRRCTYLVLDEADRMLDMG---FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 368
Query: 198 GLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNT 257
+ +S + Q + E KD L+ L++ E E+ IIF T
Sbjct: 369 DFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKEN-KTIIFVET 427
Query: 258 CKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317
+ C L +R+ +P + +H Q ER L +F+S ILIATDVASRGLD+ V
Sbjct: 428 KRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487
Query: 318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI----HLVHAIEE 365
+ VIN++ P + Y+HR+GRTAR+ +G A T T ++ L+ +EE
Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEE 539
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 205 bits (521), Expect = 8e-53
Identities = 132/352 (37%), Positives = 190/352 (53%), Gaps = 15/352 (4%)
Query: 24 QPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY-----GIFCLVLTP 78
+PTP+Q P L GRD +G A+TGSGKT A++LP + ++ PY G CLVL P
Sbjct: 193 EPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAP 252
Query: 79 TRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS 138
TRELA Q+ + GK LK I GG Q +L R + IATPGRL D L S
Sbjct: 253 TRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG 312
Query: 139 NTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTLREL-Q 197
T ++++ +LV+DEADR+L+ G F + I+ + RQTL++SAT +R+L +
Sbjct: 313 KT-NLRRCTYLVLDEADRMLDMG---FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 368
Query: 198 GLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNT 257
+ +S + Q + E KD L+ L++ E E+ IIF T
Sbjct: 369 DFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKEN-KTIIFVET 427
Query: 258 CKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317
+ C L +R+ +P + +H Q ER L +F+S ILIATDVASRGLD+ V
Sbjct: 428 KRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487
Query: 318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI----HLVHAIEE 365
+ VIN++ P + Y+HR+GRTAR+ +G A T T ++ L+ +EE
Sbjct: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEE 539
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 201 bits (510), Expect = 2e-51
Identities = 144/482 (29%), Positives = 247/482 (51%), Gaps = 28/482 (5%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F++ LS ++ ++ + T +Q I L+G+D LG AKTGSGKT AF++P+L+
Sbjct: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEA 130
Query: 64 L------SEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALEL 117
L S D G+ L+++PTRELAYQ E R +GK +I+GG D+ +A E
Sbjct: 131 LYRLQWTSTDGLGV--LIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEA-ER 187
Query: 118 SRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVP 177
++++ TPGRL H+ + +F ++ LV+DEADR+L+ G D + A++ +P
Sbjct: 188 INNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFAD---TMNAVIENLP 244
Query: 178 ARRQTLLFSATLTDTLRELQGLATNQP-FFW-EAQAPVSTVEQLDQRYLLVPEKVKDAYL 235
+RQTLLFSAT T ++++L L+ P + W +A ST L+Q Y++ + K
Sbjct: 245 KKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQK---- 300
Query: 236 VHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKF--SFPTVALHSMMKQKERFAALAK 293
+ ++ F H I+F ++CK Q L + + +ALH +Q R +
Sbjct: 301 ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE 360
Query: 294 FKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVT 353
F +L ATD+A+RGLD P V V+ + P YIHR GRTAR G+A+ ++
Sbjct: 361 FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL 420
Query: 354 QYDIHLVHAIEEQIKKKLEEFSVEEAEVLQILTQV-NVVRRECEIKLEA----AHFDEKK 408
+ +V + ++ K ++E + +++ + ++ +++ ++ ++K A +
Sbjct: 421 PSEKAMVQQLLQK-KVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSV 479
Query: 409 EINKRKQLILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRT 468
+ K K++ K P E LA + RF +K+++ ++ K PR
Sbjct: 480 YLMKDKEVFDVSKLPIPEYALSLGLAVAPRV--RFLQKMQKQPTKELVRSQADKVIEPRA 537
Query: 469 PS 470
PS
Sbjct: 538 PS 539
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 199 bits (505), Expect = 6e-51
Identities = 135/396 (34%), Positives = 203/396 (51%), Gaps = 30/396 (7%)
Query: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
+ FA G L+ Q R+ QPTP+Q +P L GRD +G AKTGSGKTAAF+ P+L
Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312
Query: 62 -----QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALE 116
QK E G +++ PTREL QI + + GK L+ + GG M QA
Sbjct: 313 IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKA 372
Query: 117 LSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176
L +V+ TPGRL DH++ T +++++ +LV DEADR+ + G F + +I + V
Sbjct: 373 LQEGAEIVVCTPGRLIDHVKKKAT-NLQRVSYLVFDEADRMFDMG---FEYQVRSIASHV 428
Query: 177 PARRQTLLFSATLTDTLREL------QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKV 230
RQTLLFSAT + +L + Q EA V+ + ++ P K
Sbjct: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSG---PSKW 485
Query: 231 KDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAA 290
L +R + S+++F + L L++ LH M Q ER
Sbjct: 486 N-----WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 291 LAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAIT 350
++ FK +L+ATDVA+RGLDIP+++ VIN++ + HR+GRT RAG +G A T
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 351 LVTQYDIH----LVHAIE---EQIKKKLEEFSVEEA 379
L+T D + LV +E + + K+L + +++ A
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 199 bits (505), Expect = 6e-51
Identities = 135/396 (34%), Positives = 203/396 (51%), Gaps = 30/396 (7%)
Query: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
+ FA G L+ Q R+ QPTP+Q +P L GRD +G AKTGSGKTAAF+ P+L
Sbjct: 253 SSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPML 312
Query: 62 -----QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALE 116
QK E G +++ PTREL QI + + GK L+ + GG M QA
Sbjct: 313 IHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKA 372
Query: 117 LSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176
L +V+ TPGRL DH++ T +++++ +LV DEADR+ + G F + +I + V
Sbjct: 373 LQEGAEIVVCTPGRLIDHVKKKAT-NLQRVSYLVFDEADRMFDMG---FEYQVRSIASHV 428
Query: 177 PARRQTLLFSATLTDTLREL------QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKV 230
RQTLLFSAT + +L + Q EA V+ + ++ P K
Sbjct: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSG---PSKW 485
Query: 231 KDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAA 290
L +R + S+++F + L L++ LH M Q ER
Sbjct: 486 N-----WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 291 LAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAIT 350
++ FK +L+ATDVA+RGLDIP+++ VIN++ + HR+GRT RAG +G A T
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 351 LVTQYDIH----LVHAIE---EQIKKKLEEFSVEEA 379
L+T D + LV +E + + K+L + +++ A
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 196 bits (498), Expect = 4e-50
Identities = 123/379 (32%), Positives = 214/379 (56%), Gaps = 16/379 (4%)
Query: 18 RQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY----GIFC 73
+++G T +Q I +LEGRD L AKTGSGKT AF++P ++ + + + G
Sbjct: 195 KEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGV 254
Query: 74 LVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLAD 133
L+L+PTRELA Q + L +I+GG + A+A +L ++++ATPGRL D
Sbjct: 255 LILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLD 314
Query: 134 HLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTL 193
H++++ F K ++ LV+DEADR+L+ G F +L+ I+ +P RRQT+LFSAT T +
Sbjct: 315 HMQNTPGFMYKNLQCLVIDEADRILDVG---FEEELKQIIKLLPTRRQTMLFSATQTRKV 371
Query: 194 RELQGLATNQPFFW---EAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWS 250
+L ++ + + + +TV+ L+Q Y++ P + + L +++ + +
Sbjct: 372 EDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKK----K 427
Query: 251 IIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASR 310
+++F ++C + + +L P +A+H KQ +R +F ++ L+ TDVA+R
Sbjct: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
Query: 311 GLDIPTVQVVINHNTPGLPKIYIHRVGRTARA-GRQGQAITLVTQYDIHLVHAIEEQIKK 369
GLDIP V ++ ++ P PK YIHRVGRTAR +G A+ ++ ++ + + +Q K
Sbjct: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYL-KQSKV 546
Query: 370 KLEEFSVEEAEVLQILTQV 388
L EF +++ I +Q+
Sbjct: 547 PLSEFDFSWSKISDIQSQL 565
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 195 bits (496), Expect = 7e-50
Identities = 118/355 (33%), Positives = 196/355 (55%), Gaps = 10/355 (2%)
Query: 19 QLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTP 78
++G ++P+P+Q IP L GRD L AK G+GK+ A+++P+L++L I +V+ P
Sbjct: 113 EMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVP 172
Query: 79 TRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRS 137
TRELA Q+++ + K +G K GG ++ + L HVVIATPGR+ D ++
Sbjct: 173 TRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKK 232
Query: 138 SNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTLRELQ 197
+ ++ +V+DEAD+LL Q DF +E I+ +P RQ LL+SAT ++++
Sbjct: 233 G-VAKVDHVQMIVLDEADKLLSQ---DFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM 288
Query: 198 GLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNT 257
+P+ + T++ + Q Y V E+ K L L R Q IIF N+
Sbjct: 289 NSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS----IIFCNS 343
Query: 258 CKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317
+ ++L + + + +H+ M+Q+ R F++ + R L+ TD+ +RG+DI V
Sbjct: 344 SQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAV 403
Query: 318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQIKKKLE 372
VVIN + P L + Y+HR+GR+ R G G AI L+T D + +IEEQ+ +++
Sbjct: 404 NVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIK 458
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 193 bits (490), Expect = 3e-49
Identities = 127/391 (32%), Positives = 211/391 (53%), Gaps = 14/391 (3%)
Query: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
+GF + L L+ G + P+ VQ CIP + G D L AK+G GKTA FVL L
Sbjct: 44 SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATL 103
Query: 62 QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPL-GLKDCIIVGGMDMVAQALELSRK 120
Q++ + LV+ TRELA+QI++++ K + +K + GG+ + L +
Sbjct: 104 QQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKN 163
Query: 121 -PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR 179
PHVV+ TPGR+ +R+ +FS+K ++ V+DE D++LEQ D D++ I P
Sbjct: 164 CPHVVVGTPGRILALVRN-RSFSLKNVKHFVLDECDKMLEQ--LDMRRDVQEIFRLTPHE 220
Query: 180 RQTLLFSATLTDTLRELQGLATNQPF--FWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237
+Q ++FSATL+ +R + P F + + + T+ L Q Y+ + + K+ L
Sbjct: 221 KQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKL-TLHGLQQYYVKLKDSEKNRKLFD 279
Query: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
L+ D E +IIF + + C L +L + +FP +A+H M Q+ER + +FK
Sbjct: 280 LL----DVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDF 335
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVT-QYD 356
RIL+AT++ RG+DI V +V N++ P Y+HRV R R G +G AIT V+ + D
Sbjct: 336 QRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 395
Query: 357 IHLVHAIEEQIKKKLEEFSVEEAEVLQILTQ 387
+++ ++++ + + E EE ++ + Q
Sbjct: 396 AKILNDVQDRFEVNVAELP-EEIDISTYIEQ 425
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 191 bits (485), Expect = 1e-48
Identities = 119/379 (31%), Positives = 199/379 (52%), Gaps = 7/379 (1%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F +GL L+ G ++P+ +Q I I++GRD + +++G+GKTA F + +LQ
Sbjct: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99
Query: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHV 123
L L+L PTRELA QI + LG + ++ +GG ++ +L HV
Sbjct: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159
Query: 124 VIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTL 183
V TPGR+ D +R + + I+ LV+DEAD +L +G + D+ L P Q +
Sbjct: 160 VAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYL---PPATQVV 215
Query: 184 LFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
L SATL + E+ P + T+E + Q ++ V ++ + +
Sbjct: 216 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVE---REEWKFDTLCDLY 272
Query: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
D +IF NT + L +R+ +F ++H M QKER + + +F+S R+LI
Sbjct: 273 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332
Query: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAI 363
+TDV +RGLD+P V ++IN++ P ++YIHR+GR+ R GR+G AI V DI ++ I
Sbjct: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
Query: 364 EEQIKKKLEEFSVEEAEVL 382
E+ +++E + A+++
Sbjct: 393 EQYYSTQIDEMPMNVADLI 411
>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
Length = 851
Score = 191 bits (485), Expect = 1e-48
Identities = 138/441 (31%), Positives = 218/441 (49%), Gaps = 61/441 (13%)
Query: 2 AGFAELGLSSWLVEQCRQ-LGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPI 60
A F ELGL L+ L + T VQ IP +LEGRD L ++TGSGKT A+ +P+
Sbjct: 230 AAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPV 289
Query: 61 LQKLS------EDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQ 113
+Q L + G + LVL PTRELA Q + + L KP + +++GG ++
Sbjct: 290 VQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSE 349
Query: 114 ALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAIL 173
L + +++I+TPGRL DH++S+ ++R+LV DEADR+L+ G F D+ IL
Sbjct: 350 KARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLG---FEKDITVIL 406
Query: 174 AAVPA---RRQTLLFSATLTDTLRELQGLATNQPF------------------FWEAQAP 212
AV A +RQ +L SATLT+ + L ++ + P E P
Sbjct: 407 NAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPP 466
Query: 213 --------VSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQ-- 262
+ E L Q +VP K++ L I + ED +++F ++C+ +
Sbjct: 467 PAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFH 526
Query: 263 ---ILCMMLRKFSFPT-------------VALHSMMKQKERFAALAKFKSSIYRILIATD 306
L +L P + LH M+Q+ER A +F S +L+ TD
Sbjct: 527 YSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTD 586
Query: 307 VASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQ 366
VA+RGLD+P V ++ +N P P YIHR+GRTAR G G ++ ++ + V+++
Sbjct: 587 VAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASH 646
Query: 367 IKKKLEEFSVEEAEVLQILTQ 387
K+ ++ ++L +LT+
Sbjct: 647 ---KINVSEIKMEDILCVLTR 664
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 191 bits (484), Expect = 2e-48
Identities = 125/363 (34%), Positives = 189/363 (52%), Gaps = 11/363 (3%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F E + +++ + +PT +Q P L G D +G A+TGSGKT +++LP +
Sbjct: 96 FYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVH 155
Query: 64 LSEDPY-----GIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELS 118
++ P+ G CLVL PTRELA Q+ + + LK I GG Q +L
Sbjct: 156 INHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
Query: 119 RKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPA 178
R + IATPGRL D L T ++++ +LV+DEADR+L+ G F + I+ +
Sbjct: 216 RGVEICIATPGRLIDFLECGKT-NLRRTTYLVLDEADRMLDMG---FEPQIRKIVDQIRP 271
Query: 179 RRQTLLFSATLTDTLREL-QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237
RQTL++SAT +R+L + + +S + Q + + KD L+
Sbjct: 272 DRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIR 331
Query: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
L++ E E+ I+F T + C L +R+ +P + +H Q+ER L +FK
Sbjct: 332 LMEEIMSEKEN-KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
ILIATDVASRGLD+ V+ VIN++ P + YIHR+GRTAR+ + G A T T +I
Sbjct: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
Query: 358 HLV 360
V
Sbjct: 451 KQV 453
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 187 bits (475), Expect = 2e-47
Identities = 121/381 (31%), Positives = 203/381 (53%), Gaps = 13/381 (3%)
Query: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
+GF + L L+ G + P+ VQ CIP + G D L AK+G GKTA FVL L
Sbjct: 45 SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATL 104
Query: 62 QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPL-GLKDCIIVGGMDMVAQALELSRK 120
Q+L + LV+ TRELA+QI++++ K + +K + GG+ + L +
Sbjct: 105 QQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN 164
Query: 121 -PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR 179
PH+V+ TPGR+ L + + ++K I+ ++DE D++LEQ D D++ I P
Sbjct: 165 CPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQ--LDMRRDVQEIFRMTPHE 221
Query: 180 RQTLLFSATLTDTLRELQGLATNQPF--FWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237
+Q ++FSATL+ +R + P F + + + T+ L Q Y+ + + K+ L
Sbjct: 222 KQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKL-TLHGLQQYYVKLKDNEKNRKLFD 280
Query: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
L+ D E ++IF + + C L +L + +FP +A+H M Q+ER + +FK
Sbjct: 281 LL----DVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDF 336
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVT-QYD 356
RIL+AT++ RG+DI V + N++ P Y+HRV R R G +G AIT V+ + D
Sbjct: 337 QRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 396
Query: 357 IHLVHAIEEQIKKKLEEFSVE 377
+++ ++++ + + E E
Sbjct: 397 AKILNDVQDRFEVNISELPDE 417
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 187 bits (475), Expect = 2e-47
Identities = 121/381 (31%), Positives = 203/381 (53%), Gaps = 13/381 (3%)
Query: 2 AGFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL 61
+GF + L L+ G + P+ VQ CIP + G D L AK+G GKTA FVL L
Sbjct: 45 SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATL 104
Query: 62 QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPL-GLKDCIIVGGMDMVAQALELSRK 120
Q+L + LV+ TRELA+QI++++ K + +K + GG+ + L +
Sbjct: 105 QQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKN 164
Query: 121 -PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPAR 179
PH+V+ TPGR+ L + + ++K I+ ++DE D++LEQ D D++ I P
Sbjct: 165 CPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQ--LDMRRDVQEIFRMTPHE 221
Query: 180 RQTLLFSATLTDTLRELQGLATNQPF--FWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237
+Q ++FSATL+ +R + P F + + + T+ L Q Y+ + + K+ L
Sbjct: 222 KQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKL-TLHGLQQYYVKLKDNEKNRKLFD 280
Query: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
L+ D E ++IF + + C L +L + +FP +A+H M Q+ER + +FK
Sbjct: 281 LL----DVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDF 336
Query: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVT-QYD 356
RIL+AT++ RG+DI V + N++ P Y+HRV R R G +G AIT V+ + D
Sbjct: 337 QRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 396
Query: 357 IHLVHAIEEQIKKKLEEFSVE 377
+++ ++++ + + E E
Sbjct: 397 AKILNDVQDRFEVNISELPDE 417
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 186 bits (471), Expect = 5e-47
Identities = 126/372 (33%), Positives = 193/372 (51%), Gaps = 29/372 (7%)
Query: 24 QPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGI------------ 71
+PTPVQ IP I E RD + CA+TGSGKTAAF+LPIL ++ D G
Sbjct: 202 RPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 261
Query: 72 ------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVI 125
LVL PTRELA QI E+ R ++ C++ GG D+ Q +L R H+++
Sbjct: 262 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 321
Query: 126 ATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILA--AVPAR--RQ 181
ATPGRL D + + ++LV+DEADR+L+ G F + I+ +P + R
Sbjct: 322 ATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---FEPQIRRIVEQDTMPPKGVRH 377
Query: 182 TLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQR 241
T++FSAT ++ L ++ F ST E + Q+ + V E K ++L+ L+
Sbjct: 378 TMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNA 437
Query: 242 FQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRI 301
+D ++F T K L L + ++H Q++R AL +F+S I
Sbjct: 438 ---TGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPI 494
Query: 302 LIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVH 361
L+AT VA+RGLDI V+ VIN + P + Y+HR+GRT R G G A + + +I++
Sbjct: 495 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITK 554
Query: 362 AIEEQIKKKLEE 373
+ + + + +E
Sbjct: 555 DLLDLLVEAKQE 566
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 185 bits (469), Expect = 9e-47
Identities = 127/377 (33%), Positives = 194/377 (51%), Gaps = 27/377 (7%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F E L L + G + TPVQ IP IL GRD + CA+TGSGKTAAF+LPIL
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
Query: 64 LSEDPYGIF-----------CLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVA 112
+ D GI C+++ PTREL QI + R ++ +I GG +
Sbjct: 350 MMHD--GITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGH 407
Query: 113 QALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAI 172
++ + +++ ATPGRL D + +K+I++LV+DEADR+L+ G F +++ +
Sbjct: 408 SIRQIVQGCNILCATPGRLMDII-GKEKIGLKQIKYLVLDEADRMLDMG---FGPEMKKL 463
Query: 173 LAA--VPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVS-TVEQLDQRYLLVP 227
++ +P++ RQTL+FSAT + ++ L + + A V + Q L V
Sbjct: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523
Query: 228 EKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKER 287
+ K LV +++ DE ++F T K + L + T ++H +Q+ER
Sbjct: 524 QFSKREKLVEILRNIGDERT----MVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 579
Query: 288 FAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQ 347
AL F+ +L+AT VA+RGLDI VQ VIN + P Y+HR+GRT R G G+
Sbjct: 580 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 639
Query: 348 AITLV-TQYDIHLVHAI 363
AI+ + D HL +
Sbjct: 640 AISFFDLESDNHLAQPL 656
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 185 bits (469), Expect = 9e-47
Identities = 127/377 (33%), Positives = 194/377 (51%), Gaps = 27/377 (7%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F E L L + G + TPVQ IP IL GRD + CA+TGSGKTAAF+LPIL
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349
Query: 64 LSEDPYGIF-----------CLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVA 112
+ D GI C+++ PTREL QI + R ++ +I GG +
Sbjct: 350 MMHD--GITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGH 407
Query: 113 QALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAI 172
++ + +++ ATPGRL D + +K+I++LV+DEADR+L+ G F +++ +
Sbjct: 408 SIRQIVQGCNILCATPGRLMDII-GKEKIGLKQIKYLVLDEADRMLDMG---FGPEMKKL 463
Query: 173 LAA--VPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVS-TVEQLDQRYLLVP 227
++ +P++ RQTL+FSAT + ++ L + + A V + Q L V
Sbjct: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 523
Query: 228 EKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKER 287
+ K LV +++ DE ++F T K + L + T ++H +Q+ER
Sbjct: 524 QFSKREKLVEILRNIGDERT----MVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 579
Query: 288 FAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQ 347
AL F+ +L+AT VA+RGLDI VQ VIN + P Y+HR+GRT R G G+
Sbjct: 580 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 639
Query: 348 AITLV-TQYDIHLVHAI 363
AI+ + D HL +
Sbjct: 640 AISFFDLESDNHLAQPL 656
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 185 bits (469), Expect = 9e-47
Identities = 127/377 (33%), Positives = 194/377 (51%), Gaps = 27/377 (7%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F E L L + G + TPVQ IP IL GRD + CA+TGSGKTAAF+LPIL
Sbjct: 256 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 315
Query: 64 LSEDPYGIF-----------CLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVA 112
+ D GI C+++ PTREL QI + R ++ +I GG +
Sbjct: 316 MMHD--GITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGH 373
Query: 113 QALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAI 172
++ + +++ ATPGRL D + +K+I++LV+DEADR+L+ G F +++ +
Sbjct: 374 SIRQIVQGCNILCATPGRLMDII-GKEKIGLKQIKYLVLDEADRMLDMG---FGPEMKKL 429
Query: 173 LAA--VPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVS-TVEQLDQRYLLVP 227
++ +P++ RQTL+FSAT + ++ L + + A V + Q L V
Sbjct: 430 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG 489
Query: 228 EKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKER 287
+ K LV +++ DE ++F T K + L + T ++H +Q+ER
Sbjct: 490 QFSKREKLVEILRNIGDERT----MVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 545
Query: 288 FAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQ 347
AL F+ +L+AT VA+RGLDI VQ VIN + P Y+HR+GRT R G G+
Sbjct: 546 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 605
Query: 348 AITLV-TQYDIHLVHAI 363
AI+ + D HL +
Sbjct: 606 AISFFDLESDNHLAQPL 622
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 182 bits (463), Expect = 5e-46
Identities = 120/380 (31%), Positives = 195/380 (51%), Gaps = 8/380 (2%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F ++ LS L+ G ++P+ +Q I ++G D + A++G+GKTA F + ILQ+
Sbjct: 34 FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93
Query: 64 LSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK-PH 122
+ D LVL PTRELA QI + LG +G +GG ++ A+ +L + PH
Sbjct: 94 IELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPH 153
Query: 123 VVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQT 182
+++ TPGR+ D L + S K I+ V+DEAD +L +G D D I + + Q
Sbjct: 154 IIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD---IFQKLNSNTQV 209
Query: 183 LLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRF 242
+L SAT+ + E+ P + T+E + Q Y+ V ++ + + +
Sbjct: 210 VLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE---REEWKLDTLCDL 266
Query: 243 QDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRIL 302
+ +IF NT + L + F A+H M QKER + +F+S R+L
Sbjct: 267 YETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVL 326
Query: 303 IATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHA 362
I TD+ +RG+D+ V +VIN++ P + YIHR+GR R GR+G AI +VT+ D +
Sbjct: 327 ITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRD 386
Query: 363 IEEQIKKKLEEFSVEEAEVL 382
IE +EE + A+++
Sbjct: 387 IETFYNTSIEEMPLNVADLI 406
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 182 bits (461), Expect = 8e-46
Identities = 132/404 (32%), Positives = 202/404 (50%), Gaps = 42/404 (10%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQ- 62
F E+ + ++ ++ G+ PTP+Q+ IP IL GRD +G A TGSGKT F LP++
Sbjct: 183 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 242
Query: 63 ----------KLSEDPYGIFCLVLTPTRELAYQ---IAEQF-RVL---GKPLGLKDCIIV 105
E PYG L++ P+RELA Q I E + R+L PL L+ + +
Sbjct: 243 CLEQEKRLPFSKREGPYG---LIICPSRELARQTHGILEYYCRLLQEDSSPL-LRCALCI 298
Query: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165
GGM + Q + H+++ATPGRL D L+ S+ R+L +DEADR+++ G F
Sbjct: 299 GGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMV-SLDICRYLALDEADRMIDMG---F 354
Query: 166 TVDLEAILAAVPARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLL 225
D+ I + +RQTLLFSAT+ ++ A +P + + Q
Sbjct: 355 EGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEY 414
Query: 226 VPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQK 285
V E+ K YL+ +Q+ ++IF + L VA+H Q+
Sbjct: 415 VKEEAKMVYLLECLQKTPPP-----VLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQE 469
Query: 286 ERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQ 345
ER A+ F+ +L+ATDVAS+GLD P +Q VIN++ P + Y+HR+GRT R+G
Sbjct: 470 ERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNT 529
Query: 346 GQAITLVTQYDIHLVHAIEEQIKKKLEEFSVEEAE----VLQIL 385
G A T + + A +E + L+ +E + VLQ+L
Sbjct: 530 GIATTFINK-------ACDESVLMDLKALLLEAKQKVPPVLQVL 566
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 180 bits (457), Expect = 2e-45
Identities = 136/408 (33%), Positives = 212/408 (51%), Gaps = 26/408 (6%)
Query: 13 LVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLP-----ILQ---KL 64
++E ++ G ++PTP+Q P +L+G D +G A+TG+GKT +++P +LQ K
Sbjct: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKG 312
Query: 65 SEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVV 124
+ G+ LVLTPTRELA Q+ + GL+ + GG + Q EL + ++
Sbjct: 313 QRNRPGM--LVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVDII 369
Query: 125 IATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLL 184
IATPGRL D L+ SN ++K I +LV+DEAD++L+ G F + IL V RQT++
Sbjct: 370 IATPGRLND-LQMSNFVNLKNITYLVLDEADKMLDMG---FEPQIMKILLDVRPDRQTVM 425
Query: 185 FSATLTDTLRELQGLATNQPFF-WEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQ 243
SAT ++ L +P + + V + Q ++ E+ K +++ +Q
Sbjct: 426 TSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMS 485
Query: 244 DEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILI 303
+ +I+F + L L + +LH +Q++R AL FK+ RILI
Sbjct: 486 STDK---VIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILI 542
Query: 304 ATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHA- 362
ATD+ASRGLD+ V V N + P + Y+HR+GRT RAGR G +IT +T+ D +
Sbjct: 543 ATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASEL 602
Query: 363 --IEEQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKK 408
I E+ + + E V AE + Q +RE E K+E KK
Sbjct: 603 INILERANQSIPEELVSMAERFKAHQQ----KREMERKMERPQGRPKK 646
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 178 bits (452), Expect = 9e-45
Identities = 123/392 (31%), Positives = 198/392 (50%), Gaps = 29/392 (7%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F+++ + ++ +PTPVQ IP I RD + CA+TGSGKTAAF+LPIL +
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239
Query: 64 LSEDPYGI------------------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIV 105
+ D G LVL PTRELA QI E+ R ++ C++
Sbjct: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299
Query: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165
GG D+ Q +L R H+++ATPGRL D + + ++LV+DEADR+L+ G F
Sbjct: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---F 355
Query: 166 TVDLEAILA--AVPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQ 221
+ I+ +P + R T++FSAT ++ L ++ F ST E + Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
Query: 222 RYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSM 281
+ + V + K ++L+ ++ D ++F T K L L + ++H
Sbjct: 416 KVVWVEDLDKRSFLLDILGA---TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
Query: 282 MKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTAR 341
Q++R AL +F+S IL+AT VA+RGLDI V+ VIN + P + Y+HR+GRT R
Sbjct: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
Query: 342 AGRQGQAITLVTQYDIHLVHAIEEQIKKKLEE 373
G G A + + ++++ + + + + +E
Sbjct: 533 VGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 178 bits (452), Expect = 9e-45
Identities = 123/392 (31%), Positives = 198/392 (50%), Gaps = 29/392 (7%)
Query: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
F+++ + ++ +PTPVQ IP I RD + CA+TGSGKTAAF+LPIL +
Sbjct: 180 FSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQ 239
Query: 64 LSEDPYGI------------------FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIV 105
+ D G LVL PTRELA QI E+ R ++ C++
Sbjct: 240 IYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVY 299
Query: 106 GGMDMVAQALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDF 165
GG D+ Q +L R H+++ATPGRL D + + ++LV+DEADR+L+ G F
Sbjct: 300 GGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRMLDMG---F 355
Query: 166 TVDLEAILA--AVPAR--RQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQ 221
+ I+ +P + R T++FSAT ++ L ++ F ST E + Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
Query: 222 RYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSM 281
+ + V + K ++L+ ++ D ++F T K L L + ++H
Sbjct: 416 KVVWVEDLDKRSFLLDILGA---TGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
Query: 282 MKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTAR 341
Q++R AL +F+S IL+AT VA+RGLDI V+ VIN + P + Y+HR+GRT R
Sbjct: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
Query: 342 AGRQGQAITLVTQYDIHLVHAIEEQIKKKLEE 373
G G A + + ++++ + + + + +E
Sbjct: 533 VGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,026,123
Number of Sequences: 37866
Number of extensions: 812381
Number of successful extensions: 4073
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 3495
Number of HSP's gapped (non-prelim): 520
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.