BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31377566 ring finger protein 168 [Homo sapiens] (571 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31377566 ring finger protein 168 [Homo sapiens] 1157 0.0 gi|148839382 ring finger protein 169 [Homo sapiens] 99 8e-21 gi|15208660 tripartite motif protein 21 [Homo sapiens] 60 4e-09 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 3e-08 gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 56 1e-07 gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 54 3e-07 gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 54 3e-07 gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 54 4e-07 gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 54 4e-07 gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 54 4e-07 gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 54 4e-07 gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 54 5e-07 gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 52 1e-06 gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 52 1e-06 gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 52 1e-06 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 52 1e-06 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 52 1e-06 gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 51 3e-06 gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 51 3e-06 gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 51 3e-06 gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 51 3e-06 gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] 51 3e-06 gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 51 3e-06 gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 51 3e-06 gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 51 3e-06 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 50 7e-06 gi|116174778 centrosome spindle pole associated protein 1 isofor... 49 1e-05 gi|116174789 centrosome spindle pole associated protein 1 isofor... 49 1e-05 >gi|31377566 ring finger protein 168 [Homo sapiens] Length = 571 Score = 1157 bits (2994), Expect = 0.0 Identities = 571/571 (100%), Positives = 571/571 (100%) Query: 1 MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60 MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS Sbjct: 1 MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60 Query: 61 WTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREY 120 WTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREY Sbjct: 61 WTRYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREY 120 Query: 121 EEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR 180 EEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR Sbjct: 121 EEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR 180 Query: 181 KLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASH 240 KLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASH Sbjct: 181 KLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASH 240 Query: 241 SEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPW 300 SEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPW Sbjct: 241 SEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPW 300 Query: 301 LCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSG 360 LCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSG Sbjct: 301 LCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSG 360 Query: 361 VTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEE 420 VTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEE Sbjct: 361 VTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEE 420 Query: 421 TEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATS 480 TEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATS Sbjct: 421 TEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATS 480 Query: 481 SPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNST 540 SPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNST Sbjct: 481 SPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNST 540 Query: 541 RDHCKVSKSAHSLQPSISQKSVFQMFQRCTK 571 RDHCKVSKSAHSLQPSISQKSVFQMFQRCTK Sbjct: 541 RDHCKVSKSAHSLQPSISQKSVFQMFQRCTK 571 >gi|148839382 ring finger protein 169 [Homo sapiens] Length = 708 Score = 99.4 bits (246), Expect = 8e-21 Identities = 111/429 (25%), Positives = 167/429 (38%), Gaps = 55/429 (12%) Query: 9 PSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRR 68 P E C C+E E LPC H+LC+ C Q + A CP CR R W R R Sbjct: 61 PRPEESGCAGCLEPPGEAAALPCGHSLCRGCAQRAADAAGPGCPRCRARGPGWARRRARD 120 Query: 69 NSLVNVE-LWTIIQKHYPRECKLRASG--------QESEEVADDYQPVRL------LSKP 113 + + E L ++ P C+ R G E E A +P + LSKP Sbjct: 121 DGQADSEVLGECARRSQPERCRPRRDGGAAAAGPRPEQEPRAAPAEPDFIFRAPIKLSKP 180 Query: 114 GELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLK 173 GELR EYE + R + +E K SE+ I +LL E+ E KR+ M+EQ K Sbjct: 181 GELREEYES-----LRKLREEKLQEEKPSEDQIHKLLPEDTETGKRK-------MDEQKK 228 Query: 174 SDEELARKLSIDINNFCEGSISASPLN--SRKSDPVTPKSEKKSKNKQRNTGDIQKYLTP 231 DE L K +++ C +S S SR T +S SKN + + L Sbjct: 229 RDEPLVLKTNLE---RCPARLSDSENEEPSRGQMTQTHRSAFVSKNNSYSLAFLAGKLNS 285 Query: 232 KSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDM-PTLSPQISLGVGEQ-- 288 K + S S S+ QE K V ++ G ++ M P +P I + + Q Sbjct: 286 KVE-RSQSCSDTAQERAKSRV---------RAVPGNKAKVTTMTPASNPIIGVLLSTQNN 335 Query: 289 ----GADSSIESPMPWLCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSKETA 344 D +IE +P+ H+ P ++ L+H +P P + Sbjct: 336 RCVSAPDLTIEKRLPFSSLSSLASLHKPERSVSPESNDSISEELNHFKPIVCSPCT---- 391 Query: 345 VMPCGRTESGCAPTSGVTQTNGNNTGETENEESCLLISKEISKRKNQESSFEAVKDPCFS 404 P R G + + ++ N + +++ S I K+ Q +K Sbjct: 392 --PPKRLPDGRVLSPLIIKSTPRNLNRSLQKQTSYEASPRILKKWEQIFQERQIKKTLSK 449 Query: 405 AKRRKVSPE 413 A ++PE Sbjct: 450 ATLTSLAPE 458 Score = 45.4 bits (106), Expect = 1e-04 Identities = 21/43 (48%), Positives = 33/43 (76%) Query: 438 ERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATS 480 ++ +QEE+DR LALQLQ+ D E+ +R+KGS D+Y LR+++ Sbjct: 661 QKLQQEEEDRQLALQLQRMFDNERRTVSRRKGSVDQYLLRSSN 703 >gi|15208660 tripartite motif protein 21 [Homo sapiens] Length = 475 Score = 60.5 bits (145), Expect = 4e-09 Identities = 56/228 (24%), Positives = 96/228 (42%), Gaps = 48/228 (21%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRR--------------- 57 E C IC++ VEPV++ C H+ C+ C + CP CR+R Sbjct: 13 EVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLKNLRPNRQLANM 72 Query: 58 ------VSSWTRYHTR--RNSLVNVELWTIIQKHYPRECKLRASGQES--------EEVA 101 +S R T+ R ++ L +K C + A ++ EE A Sbjct: 73 VNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAA 132 Query: 102 DDYQPVRLLSKPGELRREYE--EEISKVAAERRAS-----EEEENKASEEYIQR--LLAE 152 +YQ +L GELRR+ E E++ A +RA E ++++ E++Q+ L E Sbjct: 133 QEYQE-KLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVE 191 Query: 153 EEEEEKRQAEKRRRAM-------EEQLKSDEELARKLSIDINNFCEGS 193 EE+ + ++ EK R E +L + ++L +++ C S Sbjct: 192 EEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSS 239 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 57.4 bits (137), Expect = 3e-08 Identities = 112/472 (23%), Positives = 178/472 (37%), Gaps = 103/472 (21%) Query: 87 ECKLRASGQESEE-VADDYQPVRLLSK-PGELRREYEEEISKVAAERRASEEEENKASEE 144 E + +A+ QE E A++ + +R K E R+ +EE + A ER+ +EEE +A+EE Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355 Query: 145 YIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKS 204 QR+ +EEEKR AE+R+RA E +EE A+ N E A K Sbjct: 356 R-QRI----KEEEKRAAEERQRARAE----EEEKAKVEEQKRNKQLEEKKHAMQETKIKG 406 Query: 205 DPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSP 264 + V K E K N+++ D + K Q + +++ + +D P Sbjct: 407 EKVEQKIEGKWVNEKKAQEDKLQTAVLKKQ---GEEKGTKVQAKREKLQED-------KP 456 Query: 265 TGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMPWLCACGAEWYHEGNVKTRPSNHGKE 324 T + EI+D ++ ++S M +G + + N Sbjct: 457 TFKKEEIKDEKIKK--------DKEPKEEVKSFMD---------RKKGFTEVKSQNGE-- 497 Query: 325 LCVLSHERPKTRVPYSKETAVMPCGRTESGCAPTSGVTQTNG--------NNTGETENEE 376 ++H+ T +S+ P GR G Q GETE+EE Sbjct: 498 --FMTHKLKHTENTFSR-----PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEE 550 Query: 377 SCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLL 436 E K+K QE++ E + +RRKV E Sbjct: 551 F------EKLKQKQQEAALELEELKKKREERRKVLEEEE--------------------- 583 Query: 437 FERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKD 496 +R KQEE DR L + +K KE++ R + + ++K P+D Sbjct: 584 -QRRKQEEADRKLREEEEKRRLKEEIERRRAEAA-----------------EKRQKMPED 625 Query: 497 GNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNSTRDHCKVSK 548 G + K TP+ S + L +SV + ST VSK Sbjct: 626 GLSDDKKPFKCFTPKGSSLKIEERAEF---LNKSVQKSSGVKSTHQAAIVSK 674 Score = 43.9 bits (102), Expect = 4e-04 Identities = 85/435 (19%), Positives = 168/435 (38%), Gaps = 69/435 (15%) Query: 115 ELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQL-- 172 ELRR+ EE+ ++ AER A + + ++EE+ E+RRRA +E+L Sbjct: 9 ELRRQKREEM-RLEAERIAYQRND---------------DDEEEAARERRRRARQERLRQ 52 Query: 173 KSDEELARKLSIDINNFCEGSI-----SASPLNSR-KSDPVTPKSEKKSKNKQRNTGDIQ 226 K +EE +++ + + S+ + N++ + D E+ ++ ++R +Q Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112 Query: 227 KYLTPKSQFG----SASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDT-EIEDMPTLSPQI 281 + L + +F AS S + ++ D+ + + KS + Q+ EIE+ T++ Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172 Query: 282 SLGVGEQGADSSIESPMPWLCACGAEWYHEGNVKTRPSNHGKELCVLSHERPKTRVPYSK 341 +W K +E E+PK Sbjct: 173 QKN----------------------DWRDAEENKKEDKEKEEE----EEEKPKRGSIGEN 206 Query: 342 ETAVMPCGRTESGCAPTSGVTQTNGN-NTGETENEESCLLISKEISKRKNQESS----FE 396 + VM +T T ++ NG ++ E + EE S EIS + E E Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266 Query: 397 AVKDPCFSAKRRKVSPESSPD--QEETEINFTQKLIDLEHLLFERHKQEEQDRLLALQLQ 454 A + + +R ++ E E I +K E ER + EE++R+ + + Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER---ERREAEERERMRE-EEK 322 Query: 455 KEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKDGNFKRQTHTKHPTPERGS 514 + ++ Q + +K + +E R +K +R+ K+ + + E Sbjct: 323 RAAEERQRIKEEEKRAAEE---RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379 Query: 515 RDKNRQVSLKMQLKQ 529 + K + QL++ Sbjct: 380 KAKVEEQKRNKQLEE 394 Score = 31.6 bits (70), Expect = 2.1 Identities = 47/212 (22%), Positives = 86/212 (40%), Gaps = 21/212 (9%) Query: 119 EYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRR-RAMEEQLKSDEE 177 E + + ++ R +E EE + ++ Q E EE +K++ E+R+ EEQ + EE Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE 590 Query: 178 LARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGS 237 RKL + E + R+++ +EK+ K + D +K P F Sbjct: 591 ADRKLREEE----EKRRLKEEIERRRAE----AAEKRQKMPEDGLSDDKK---PFKCFTP 639 Query: 238 ASHSEAVQEVRKDSVSKDIDSSDRKSPTGQ-------DTEIEDMPTLSPQISLGVGEQGA 290 S ++E R + ++K + S T Q D+ +E + + A Sbjct: 640 KGSSLKIEE-RAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698 Query: 291 DSSIESPMPWLCACGAEWYHEGNVKTRPSNHG 322 S + P + + W +GNV + P+ G Sbjct: 699 ASDLPVPAEGVRNIKSMW-EKGNVFSSPTAAG 729 >gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo sapiens] Length = 773 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Query: 3 LPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWT 62 +P++ I +S+ +C +CM + EPVT PC H+ CK C + ++ A CP C+ S Sbjct: 467 IPEELI-DVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPY-CPLCK---ESLK 521 Query: 63 RYHTRRNSLVNVELWTIIQKHYPRECKLRASGQESE 98 Y R V L +I K+ P E R + E Sbjct: 522 EYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEE 557 Score = 37.0 bits (84), Expect = 0.049 Identities = 37/154 (24%), Positives = 61/154 (39%), Gaps = 21/154 (13%) Query: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL--- 71 +C C L EPVT+PC H+ C+ C + + C CR R+ T T Sbjct: 122 RCLGCRGFLSEPVTVPCGHSYCRRCLRRELRAR---CRLCRDRLPPATASATDAEGTAPR 178 Query: 72 --------------VNVELWTIIQKHYP-RECKLRASGQESEEVADDYQPVRLLSKPGEL 116 +V L + +K +P + + RA+G+ E + L + L Sbjct: 179 PPPLAAAIAASDFRTSVVLNHLAEKWFPGQRERARAAGRLGELLHQGRYREALAAACEAL 238 Query: 117 RREYEEEISKVAAERRASEEEENKASEEYIQRLL 150 R E + I K+ + +E KA+ E + +L Sbjct: 239 RAEPSDLIVKIYRAESYAGLQEFKAAIEDLNAVL 272 >gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo sapiens] Length = 326 Score = 54.3 bits (129), Expect = 3e-07 Identities = 64/273 (23%), Positives = 107/273 (39%), Gaps = 75/273 (27%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCF-----QSTVEKASLCCPFCRRRVSSWTRYHTR 67 E C IC+E+L +P++L C H+ C+ C +S ++K CP CR + Sbjct: 12 EVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRIS-------YQP 64 Query: 68 RNSLVNVELWTIIQKHYPRECKLRASGQE------------------------------- 96 N N + I++K RE KL GQ+ Sbjct: 65 ENIRPNRHVANIVEK--LREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122 Query: 97 --------SEEVADDYQPVRLLSKPGELRREYE--EEISKVAAERRAS-------EEEEN 139 +EEVA +YQ V+L + LR++ + EE+ E +AS ++ Sbjct: 123 HRGHHTFLTEEVAQEYQ-VKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNV 181 Query: 140 KASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDE-------ELARKLSIDINNFCEG 192 A E ++ +L EE E + EK + + L + E + R+L D+ + +G Sbjct: 182 LADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQG 241 Query: 193 SI-----SASPLNSRKSDPVTPKSEKKSKNKQR 220 S+ + R + K E KN++R Sbjct: 242 SVMELLQGVDGVIKRTENVTLKKPETFPKNQRR 274 >gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo sapiens] Length = 347 Score = 54.3 bits (129), Expect = 3e-07 Identities = 64/273 (23%), Positives = 107/273 (39%), Gaps = 75/273 (27%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCF-----QSTVEKASLCCPFCRRRVSSWTRYHTR 67 E C IC+E+L +P++L C H+ C+ C +S ++K CP CR + Sbjct: 12 EVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRIS-------YQP 64 Query: 68 RNSLVNVELWTIIQKHYPRECKLRASGQE------------------------------- 96 N N + I++K RE KL GQ+ Sbjct: 65 ENIRPNRHVANIVEK--LREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122 Query: 97 --------SEEVADDYQPVRLLSKPGELRREYE--EEISKVAAERRAS-------EEEEN 139 +EEVA +YQ V+L + LR++ + EE+ E +AS ++ Sbjct: 123 HRGHHTFLTEEVAQEYQ-VKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNV 181 Query: 140 KASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDE-------ELARKLSIDINNFCEG 192 A E ++ +L EE E + EK + + L + E + R+L D+ + +G Sbjct: 182 LADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQG 241 Query: 193 SI-----SASPLNSRKSDPVTPKSEKKSKNKQR 220 S+ + R + K E KN++R Sbjct: 242 SVMELLQGVDGVIKRTENVTLKKPETFPKNQRR 274 >gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sapiens] Length = 1268 Score = 53.9 bits (128), Expect = 4e-07 Identities = 52/212 (24%), Positives = 95/212 (44%), Gaps = 10/212 (4%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSD 205 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ + E + R+ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQQEREQRRHYEEQMRRE--EERRRA 440 Query: 206 PVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPT 265 + ++K +QR +Q+ L + + S QE R + SP+ Sbjct: 441 EHEQEYKRKQLEEQRQAERLQRQLKQERDY-LVSLQHQRQEQRPVEKKPLYHYKEGMSPS 499 Query: 266 GQDTEIEDMPTLSPQISLGVGEQGADSSIESP 297 + +++P L S G + S E P Sbjct: 500 EKPAWAKEIPHLVAVKSQGPALTASQSVHEQP 531 >gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sapiens] Length = 1276 Score = 53.9 bits (128), Expect = 4e-07 Identities = 52/212 (24%), Positives = 95/212 (44%), Gaps = 10/212 (4%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSD 205 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ + E + R+ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQQEREQRRHYEEQMRRE--EERRRA 440 Query: 206 PVTPKSEKKSKNKQRNTGDIQKYLTPKSQFGSASHSEAVQEVRKDSVSKDIDSSDRKSPT 265 + ++K +QR +Q+ L + + S QE R + SP+ Sbjct: 441 EHEQEYKRKQLEEQRQAERLQRQLKQERDY-LVSLQHQRQEQRPVEKKPLYHYKEGMSPS 499 Query: 266 GQDTEIEDMPTLSPQISLGVGEQGADSSIESP 297 + +++P L S G + S E P Sbjct: 500 EKPAWAKEIPHLVAVKSQGPALTASQSVHEQP 531 >gi|73747840 LON peptidase N-terminal domain and ring finger 3 isoform 1 [Homo sapiens] Length = 759 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 12 SECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL 71 S+ +C +CM + EPVT PC HT C C + ++ + CP C+ +S R Sbjct: 463 SDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDH-NAKCPLCKDGLSQCL---ASRKYS 518 Query: 72 VNVELWTIIQKHYPRECKLRASGQESE 98 NV + +I K P E K R E E Sbjct: 519 KNVIMEELIAKFLPEELKERRKLYEEE 545 Score = 33.9 bits (76), Expect = 0.41 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60 +C C L +PV+L C HT CK C + A C C ++S+ Sbjct: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERG-RAADRRCALCGVKLSA 201 >gi|37622896 LON peptidase N-terminal domain and ring finger 3 isoform 2 [Homo sapiens] Length = 718 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 12 SECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL 71 S+ +C +CM + EPVT PC HT C C + ++ + CP C+ +S R Sbjct: 422 SDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDH-NAKCPLCKDGLSQCL---ASRKYS 477 Query: 72 VNVELWTIIQKHYPRECKLRASGQESE 98 NV + +I K P E K R E E Sbjct: 478 KNVIMEELIAKFLPEELKERRKLYEEE 504 Score = 33.9 bits (76), Expect = 0.41 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60 +C C L +PV+L C HT CK C + A C C ++S+ Sbjct: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERG-RAADRRCALCGVKLSA 201 >gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo sapiens] Length = 493 Score = 53.5 bits (127), Expect = 5e-07 Identities = 63/273 (23%), Positives = 107/273 (39%), Gaps = 75/273 (27%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCF-----QSTVEKASLCCPFCRRRVSSWTRYHTR 67 E C IC+E+L +P++L C H+ C+ C +S ++K CP CR + Sbjct: 12 EVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRIS-------YQP 64 Query: 68 RNSLVNVELWTIIQKHYPRECKLRASGQE------------------------------- 96 N N + +++K RE KL GQ+ Sbjct: 65 ENIRPNRHVANLVEK--LREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQE 122 Query: 97 --------SEEVADDYQPVRLLSKPGELRREYE--EEISKVAAERRAS-------EEEEN 139 +EEVA +YQ V+L + LR++ + EE+ E +AS ++ Sbjct: 123 HRGHHTFPTEEVAQEYQ-VKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNV 181 Query: 140 KASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDE-------ELARKLSIDINNFCEG 192 A E ++ +L EE E + EK + + L + E + R+L D+ + +G Sbjct: 182 LADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQG 241 Query: 193 SI-----SASPLNSRKSDPVTPKSEKKSKNKQR 220 S+ + R + K E KN++R Sbjct: 242 SVMELLQGVDGVIKRTENVTLKKPETFPKNQRR 274 >gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sapiens] Length = 1323 Score = 52.4 bits (124), Expect = 1e-06 Identities = 51/216 (23%), Positives = 97/216 (44%), Gaps = 11/216 (5%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSD 205 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ + E + R+ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQQEREQRRHYEEQMRRE--EERRRA 440 Query: 206 PVTPKSEKKSKNKQRNTGDIQKYLTPKSQF-GSASHSEAVQE-VRKDSVSKDIDSSDRKS 263 + ++K +QR +Q+ L + + S H Q V K + + Sbjct: 441 EHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSE 500 Query: 264 PTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMP 299 E+E+ L+ Q S + + A+ + +P Sbjct: 501 KPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLP 536 >gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sapiens] Length = 1331 Score = 52.4 bits (124), Expect = 1e-06 Identities = 51/216 (23%), Positives = 97/216 (44%), Gaps = 11/216 (5%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCEGSISASPLNSRKSD 205 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ + E + R+ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQQEREQRRHYEEQMRRE--EERRRA 440 Query: 206 PVTPKSEKKSKNKQRNTGDIQKYLTPKSQF-GSASHSEAVQE-VRKDSVSKDIDSSDRKS 263 + ++K +QR +Q+ L + + S H Q V K + + Sbjct: 441 EHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSE 500 Query: 264 PTGQDTEIEDMPTLSPQISLGVGEQGADSSIESPMP 299 E+E+ L+ Q S + + A+ + +P Sbjct: 501 KPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLP 536 >gi|148528975 LON peptidase N-terminal domain and ring finger 2 [Homo sapiens] Length = 754 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Query: 11 LSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNS 70 +++ +C +CM +L EPVT PC HT C C + ++ A CP C+ ++S RN Sbjct: 444 VTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAP-HCPLCKDKLSELL---ASRNF 499 Query: 71 LVNVELWTIIQKHYPREC--KLRASGQESEEVAD 102 + V +I ++ P E + R +E E+++ Sbjct: 500 NITVLAEELIFRYLPDELSDRKRIYDEEMSELSN 533 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 20/91 (21%) Query: 16 CGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVE 75 C C +L +PVTLPC T+CK C + + P RR VNV Sbjct: 143 CPRCRRLLHKPVTLPCGLTVCKRCVEPGPAR-----PQVRR---------------VNVV 182 Query: 76 LWTIIQKHYPRECKLRASGQESEEVADDYQP 106 L +++K +P EC+LR ++ + QP Sbjct: 183 LSGLLEKCFPAECRLRRLAGQARSLQRQQQP 213 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 52.0 bits (123), Expect = 1e-06 Identities = 53/193 (27%), Positives = 80/193 (41%), Gaps = 37/193 (19%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVE--KASLCCPFCRRRVSSWTRYHTRR-- 68 E C +C+E L EPV + C H CK C E + CP CR+ +RY + R Sbjct: 26 EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKT----SRYRSLRPN 81 Query: 69 ---NSLVNVELWTIIQKHYPRECKLRASGQESEEV--ADDYQPVRLLSKPGELRR----- 118 S+V + K R+ L E+ + +D + V L+ R Sbjct: 82 RQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVV 141 Query: 119 -------EYEEEISKV--AAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAME 169 EY+E++ K E++ E K+SEE ++ E KR E RR + Sbjct: 142 PLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEE-------KKPGELKRLVESRR---Q 191 Query: 170 EQLKSDEELARKL 182 + L+ EEL R+L Sbjct: 192 QILREFEELHRRL 204 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 52.0 bits (123), Expect = 1e-06 Identities = 53/193 (27%), Positives = 80/193 (41%), Gaps = 37/193 (19%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVE--KASLCCPFCRRRVSSWTRYHTRR-- 68 E C +C+E L EPV + C H CK C E + CP CR+ +RY + R Sbjct: 26 EASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKT----SRYRSLRPN 81 Query: 69 ---NSLVNVELWTIIQKHYPRECKLRASGQESEEV--ADDYQPVRLLSKPGELRR----- 118 S+V + K R+ L E+ + +D + V L+ R Sbjct: 82 RQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVV 141 Query: 119 -------EYEEEISKV--AAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAME 169 EY+E++ K E++ E K+SEE ++ E KR E RR + Sbjct: 142 PLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEE-------KKPGELKRLVESRR---Q 191 Query: 170 EQLKSDEELARKL 182 + L+ EEL R+L Sbjct: 192 QILREFEELHRRL 204 >gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sapiens] Length = 1297 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQ 418 Score = 34.3 bits (77), Expect = 0.32 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 18/75 (24%) Query: 115 ELRREYEEEISKVAAERRASEE--------EENKASEEYIQRLLAEEEE----------E 156 E RR YEE++ + RRA E EE + E +Q+ L E+ E Sbjct: 422 EQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLE 481 Query: 157 EKRQAEKRRRAMEEQ 171 E+RQAE+ +R ++++ Sbjct: 482 EQRQAERLQRQLKQE 496 Score = 29.6 bits (65), Expect = 7.8 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 81 QKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEE---- 136 Q+ E K + + + + + + R L + + RRE E + +RR EE Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEE--QQRREKELRKQQEREQRRHYEEQMRR 433 Query: 137 EENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEEL 178 EE + E+ Q + + EEE+RQ E +++QL ++ L Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQAL 471 >gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sapiens] Length = 1305 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQ 418 Score = 34.3 bits (77), Expect = 0.32 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 18/75 (24%) Query: 115 ELRREYEEEISKVAAERRASEE--------EENKASEEYIQRLLAEEEE----------E 156 E RR YEE++ + RRA E EE + E +Q+ L E+ E Sbjct: 422 EQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLE 481 Query: 157 EKRQAEKRRRAMEEQ 171 E+RQAE+ +R ++++ Sbjct: 482 EQRQAERLQRQLKQE 496 Score = 29.6 bits (65), Expect = 7.8 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 81 QKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEE---- 136 Q+ E K + + + + + + R L + + RRE E + +RR EE Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEE--QQRREKELRKQQEREQRRHYEEQMRR 433 Query: 137 EENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEEL 178 EE + E+ Q + + EEE+RQ E +++QL ++ L Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQAL 471 >gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sapiens] Length = 1352 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQ 418 Score = 34.3 bits (77), Expect = 0.32 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 18/75 (24%) Query: 115 ELRREYEEEISKVAAERRASEE--------EENKASEEYIQRLLAEEEE----------E 156 E RR YEE++ + RRA E EE + E +Q+ L E+ E Sbjct: 422 EQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLE 481 Query: 157 EKRQAEKRRRAMEEQ 171 E+RQAE+ +R ++++ Sbjct: 482 EQRQAERLQRQLKQE 496 Score = 29.6 bits (65), Expect = 7.8 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 81 QKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEE---- 136 Q+ E K + + + + + + R L + + RRE E + +RR EE Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEE--QQRREKELRKQQEREQRRHYEEQMRR 433 Query: 137 EENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEEL 178 EE + E+ Q + + EEE+RQ E +++QL ++ L Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQAL 471 >gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sapiens] Length = 1360 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 7/96 (7%) Query: 92 ASGQESEEVADDYQPVRLLSKPGE--LRREYEE----EISKVAAERRASEEEENKASEEY 145 + +E EE D +P +L+ PGE LRR++ + A RR E++ + +EE+ Sbjct: 324 SGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEH 383 Query: 146 IQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 ++LLAE ++ + Q E+RRR +EEQ + ++EL ++ Sbjct: 384 KRQLLAERQKRIEEQKEQRRR-LEEQQRREKELRKQ 418 Score = 34.3 bits (77), Expect = 0.32 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 18/75 (24%) Query: 115 ELRREYEEEISKVAAERRASEE--------EENKASEEYIQRLLAEEEE----------E 156 E RR YEE++ + RRA E EE + E +Q+ L E+ E Sbjct: 422 EQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLE 481 Query: 157 EKRQAEKRRRAMEEQ 171 E+RQAE+ +R ++++ Sbjct: 482 EQRQAERLQRQLKQE 496 Score = 29.6 bits (65), Expect = 7.8 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 81 QKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEE---- 136 Q+ E K + + + + + + R L + + RRE E + +RR EE Sbjct: 376 QQRENEEHKRQLLAERQKRIEEQKEQRRRLEE--QQRREKELRKQQEREQRRHYEEQMRR 433 Query: 137 EENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEEL 178 EE + E+ Q + + EEE+RQ E +++QL ++ L Sbjct: 434 EEERRRAEHEQEYIRRQLEEEQRQLE----ILQQQLLHEQAL 471 >gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens] Length = 270 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 32/180 (17%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA------SLCCPFCRRRVSSWTRYHT 66 E C IC+E+L EP++L C H+LC+ C + ++A CP C S++ H Sbjct: 12 EVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG---ISYSFEHL 68 Query: 67 RRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISK 126 + N L I+++ +E KL + ++ D + GE + +E K Sbjct: 69 QANQ----HLANIVER--LKEVKLSPDNGKKRDLCDHH---------GEKLLLFCKEDRK 113 Query: 127 VAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDI 186 V +E++ + EE ++ +++ +A+ ++LK +EE A KL DI Sbjct: 114 VIC-WLCERSQEHRGHHTVL-------TEEVFKECQEKLQAVLKRLKKEEEEAEKLEADI 165 >gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 32/180 (17%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA------SLCCPFCRRRVSSWTRYHT 66 E C IC+E+L EP++L C H+LC+ C + ++A CP C S++ H Sbjct: 12 EVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG---ISYSFEHL 68 Query: 67 RRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISK 126 + N L I+++ +E KL + ++ D + GE + +E K Sbjct: 69 QANQ----HLANIVER--LKEVKLSPDNGKKRDLCDHH---------GEKLLLFCKEDRK 113 Query: 127 VAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDI 186 V +E++ + EE ++ +++ +A+ ++LK +EE A KL DI Sbjct: 114 VIC-WLCERSQEHRGHHTVL-------TEEVFKECQEKLQAVLKRLKKEEEEAEKLEADI 165 >gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] Length = 488 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 32/180 (17%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA------SLCCPFCRRRVSSWTRYHT 66 E C IC+E+L EP++L C H+LC+ C + ++A CP C S++ H Sbjct: 12 EVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG---ISYSFEHL 68 Query: 67 RRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISK 126 + N L I+++ +E KL + ++ D + GE + +E K Sbjct: 69 QANQ----HLANIVER--LKEVKLSPDNGKKRDLCDHH---------GEKLLLFCKEDRK 113 Query: 127 VAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDI 186 V +E++ + EE ++ +++ +A+ ++LK +EE A KL DI Sbjct: 114 VIC-WLCERSQEHRGHHTVL-------TEEVFKECQEKLQAVLKRLKKEEEEAEKLEADI 165 >gi|51477690 tripartite motif-containing 6 and tripartite motif-containing 34 [Homo sapiens] Length = 842 Score = 50.8 bits (120), Expect = 3e-06 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 32/180 (17%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKA------SLCCPFCRRRVSSWTRYHT 66 E C IC+E+L EP++L C H+LC+ C + ++A CP C S++ H Sbjct: 366 EVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG---ISYSFEHL 422 Query: 67 RRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISK 126 + N L I+++ +E KL + ++ D + GE + +E K Sbjct: 423 QANQ----HLANIVER--LKEVKLSPDNGKKRDLCDHH---------GEKLLLFCKEDRK 467 Query: 127 VAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDI 186 V +E++ + EE ++ +++ +A+ ++LK +EE A KL DI Sbjct: 468 VIC-WLCERSQEHRGHHTVL-------TEEVFKECQEKLQAVLKRLKKEEEEAEKLEADI 519 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/177 (24%), Positives = 80/177 (45%), Gaps = 32/177 (18%) Query: 13 ECQCGICMEILVEPVTLPCNHTLCKPCF-----QSTV-EKASLCCPFCRRRVSSWTRYHT 66 E C IC+E+L EP+++ C H+ C+ C +S + ++ CP C+ T Y Sbjct: 40 EVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ------TSYQP 93 Query: 67 RRNSLVNVELWTIIQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISK 126 N N L I+++ RE L Q + D+ GE + + +E K Sbjct: 94 -GNLRPNRHLANIVRR--LREVVLGPGKQLKAVLCADH---------GEKLQLFCQEDGK 141 Query: 127 VAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLS 183 V +E++ ++ +A+E +E+ +++ K+ LK++E+ A KL+ Sbjct: 142 VIC-WLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKK-------LKNEEQEAEKLT 190 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 49.7 bits (117), Expect = 7e-06 Identities = 33/104 (31%), Positives = 62/104 (59%), Gaps = 10/104 (9%) Query: 87 ECKLRASGQESEEVAD-DYQPVRLLSKPGE--LRREY------EEEISKVAAERRASEEE 137 E + S +E EEV + + +P +++ PGE LRR++ +E S+ ++ +E+ Sbjct: 320 EYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ 379 Query: 138 ENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 + + EEY ++LLAE ++ ++Q E+RRR +EEQ + + E R+ Sbjct: 380 QLREQEEYKRQLLAERQKRIEQQKEQRRR-LEEQQRREREARRQ 422 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 8/120 (6%) Query: 69 NSLVNVELWTIIQKHYPR---ECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEIS 125 +S+VNV + +++ + R E K R+ +++ + Q +L E ++ I Sbjct: 341 SSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400 Query: 126 KVAAERRASEEEENKASE-----EYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR 180 + +RR EE++ + E E QR +EE+ + E+RR+ EE+ +++EE R Sbjct: 401 QQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460 Score = 37.7 bits (86), Expect = 0.029 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 1/102 (0%) Query: 115 ELRREYE-EEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLK 173 E RR+ E E+ + E+R EE E + EE +R EE+ +R+ E RR +EE+ + Sbjct: 418 EARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477 Query: 174 SDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKS 215 E L ++L + P +S++ P + K S Sbjct: 478 HLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPS 519 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 14/135 (10%) Query: 383 KEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLLFERHKQ 442 K I ++K Q E + A+R++ + +QEE LE L ER ++ Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR--------RLEEL--ERRRK 446 Query: 443 EEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKDGNFKRQ 502 EE++R A + ++ V++EQ RQ ++ HL ++L Q D Sbjct: 447 EEEERRRAEEEKRRVEREQEYIRRQL-EEEQRHLEVLQ---QQLLQEQAMLLHDHRRPHP 502 Query: 503 THTKHPTPERGSRDK 517 H++ P P + R K Sbjct: 503 QHSQQPPPPQQERSK 517 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 49.7 bits (117), Expect = 7e-06 Identities = 33/104 (31%), Positives = 62/104 (59%), Gaps = 10/104 (9%) Query: 87 ECKLRASGQESEEVAD-DYQPVRLLSKPGE--LRREY------EEEISKVAAERRASEEE 137 E + S +E EEV + + +P +++ PGE LRR++ +E S+ ++ +E+ Sbjct: 320 EYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ 379 Query: 138 ENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 + + EEY ++LLAE ++ ++Q E+RRR +EEQ + + E R+ Sbjct: 380 QLREQEEYKRQLLAERQKRIEQQKEQRRR-LEEQQRREREARRQ 422 Score = 40.4 bits (93), Expect = 0.004 Identities = 47/187 (25%), Positives = 78/187 (41%), Gaps = 24/187 (12%) Query: 115 ELRREYE-EEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLK 173 E RR+ E E+ + E+R EE E + EE +R EE+ +R+ E RR +EE+ + Sbjct: 418 EARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477 Query: 174 SDEELARKLSIDINNFCEGSISASPLNSRKSDPVTPKSEKKSKNKQRNTGDIQKYLTPKS 233 E L ++L + P +S++ P + K S + PK+ Sbjct: 478 HLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPE----------PKA 527 Query: 234 QFGSASHSEAVQEVRKDSVSKDIDSSDRKSPTGQDTEIEDMPTLSPQISLGVGEQGADSS 293 + A + +EV + S+ S R SP S Q + G++ + SS Sbjct: 528 HYEPA---DRAREVPVRTTSRSPVLSRRDSPLQG----------SGQQNSQAGQRNSTSS 574 Query: 294 IESPMPW 300 IE + W Sbjct: 575 IEPRLLW 581 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 8/120 (6%) Query: 69 NSLVNVELWTIIQKHYPR---ECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEIS 125 +S+VNV + +++ + R E K R+ +++ + Q +L E ++ I Sbjct: 341 SSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400 Query: 126 KVAAERRASEEEENKASE-----EYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR 180 + +RR EE++ + E E QR +EE+ + E+RR+ EE+ +++EE R Sbjct: 401 QQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 14/135 (10%) Query: 383 KEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLLFERHKQ 442 K I ++K Q E + A+R++ + +QEE LE L ER ++ Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR--------RLEEL--ERRRK 446 Query: 443 EEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQRKNPKDGNFKRQ 502 EE++R A + ++ V++EQ RQ ++ HL ++L Q D Sbjct: 447 EEEERRRAEEEKRRVEREQEYIRRQL-EEEQRHLEVLQ---QQLLQEQAMLLHDHRRPHP 502 Query: 503 THTKHPTPERGSRDK 517 H++ P P + R K Sbjct: 503 QHSQQPPPPQQERSK 517 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 49.7 bits (117), Expect = 7e-06 Identities = 33/104 (31%), Positives = 62/104 (59%), Gaps = 10/104 (9%) Query: 87 ECKLRASGQESEEVAD-DYQPVRLLSKPGE--LRREY------EEEISKVAAERRASEEE 137 E + S +E EEV + + +P +++ PGE LRR++ +E S+ ++ +E+ Sbjct: 320 EYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQ 379 Query: 138 ENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARK 181 + + EEY ++LLAE ++ ++Q E+RRR +EEQ + + E R+ Sbjct: 380 QLREQEEYKRQLLAERQKRIEQQKEQRRR-LEEQQRREREARRQ 422 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 8/120 (6%) Query: 69 NSLVNVELWTIIQKHYPR---ECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEIS 125 +S+VNV + +++ + R E K R+ +++ + Q +L E ++ I Sbjct: 341 SSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400 Query: 126 KVAAERRASEEEENKASE-----EYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELAR 180 + +RR EE++ + E E QR +EE+ + E+RR+ EE+ +++EE R Sbjct: 401 QQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRR 460 Score = 37.0 bits (84), Expect = 0.049 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 1/69 (1%) Query: 115 ELRREYE-EEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLK 173 E RR+ E E+ + E+R EE E + EE +R EE+ +R+ E RR +EE+ + Sbjct: 418 EARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQR 477 Query: 174 SDEELARKL 182 E L ++L Sbjct: 478 HLEVLQQQL 486 Score = 31.2 bits (69), Expect = 2.7 Identities = 34/190 (17%), Positives = 74/190 (38%), Gaps = 21/190 (11%) Query: 373 ENEESCLLISKEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEIN-FTQKLID 431 E EE L +E+ +R+ +E ++ +R + ++E+ + Q+L+ Sbjct: 431 EQEEKRRL--EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQ 488 Query: 432 LEHLLFERHKQEEQDRLLALQLQKEVDKEQMVPNRQKGSPDEYHLRATSSPPDKVLNGQR 491 + +L E +E ++ A +LQ+++ +EQ + H + + PP Sbjct: 489 EQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPP------- 541 Query: 492 KNPKDGNFKRQTHTKHPTPERGSRDKNRQVSLKMQLKQSVNRRKMPNSTRDHCKVSKSAH 551 P+ K H P D+ R+V +R + N + + ++ Sbjct: 542 --PQQERSKPSFHAPEPKAHYEPADRAREVE---------DRFRKTNHSSPEAQSKQTGR 590 Query: 552 SLQPSISQKS 561 L+P + +S Sbjct: 591 VLEPPVPSRS 600 Score = 30.8 bits (68), Expect = 3.5 Identities = 37/117 (31%), Positives = 52/117 (44%), Gaps = 25/117 (21%) Query: 80 IQKHYPRECKLRASGQESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEEN 139 +++ RE + R QE E+ + + R L EL R +EE E R EEE Sbjct: 409 LEEQQRREREARRQ-QEREQRRREQEEKRRLE---ELERRRKEE------EERRRAEEEK 458 Query: 140 KASE---EYIQRLLAEEE-----------EEEKRQAEKRRRAMEEQLKSDEELARKL 182 + E EYI+R L EE+ +E+ E R R MEE + E L R+L Sbjct: 459 RRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEH-RQAERLQRQL 514 Score = 30.0 bits (66), Expect = 6.0 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 10/85 (11%) Query: 383 KEISKRKNQESSFEAVKDPCFSAKRRKVSPESSPDQEETEINFTQKLIDLEHLLFERHKQ 442 K I ++K Q E + A+R++ + +QEE LE L ER ++ Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR--------RLEEL--ERRRK 446 Query: 443 EEQDRLLALQLQKEVDKEQMVPNRQ 467 EE++R A + ++ V++EQ RQ Sbjct: 447 EEEERRRAEEEKRRVEREQEYIRRQ 471 >gi|116174778 centrosome spindle pole associated protein 1 isoform b [Homo sapiens] Length = 1221 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 21/151 (13%) Query: 95 QESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEE 154 +E +A++ + RL + +++EYEEE K +R EEE+ +EE+I+ LAEE Sbjct: 754 RERLRIAEEKEERRLAEQRARIQQEYEEEQEK----KREKEEEQRLKNEEHIR--LAEER 807 Query: 155 EEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCE--GSISASPLNSRKSDPVTPKSE 212 ++E AE++++ EE K ++ + ++CE I + R+ P+ P + Sbjct: 808 QKE---AERKKKEEEE----------KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQ 854 Query: 213 KKSKNKQRNTGDIQKYLTPKSQFGSASHSEA 243 K +K + + + S S +++ Sbjct: 855 NKIASKLQRPPSVDSIIRSFIHESSMSRAQS 885 >gi|116174789 centrosome spindle pole associated protein 1 isoform a [Homo sapiens] Length = 1256 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 21/151 (13%) Query: 95 QESEEVADDYQPVRLLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEE 154 +E +A++ + RL + +++EYEEE K +R EEE+ +EE+I+ LAEE Sbjct: 789 RERLRIAEEKEERRLAEQRARIQQEYEEEQEK----KREKEEEQRLKNEEHIR--LAEER 842 Query: 155 EEEKRQAEKRRRAMEEQLKSDEELARKLSIDINNFCE--GSISASPLNSRKSDPVTPKSE 212 ++E AE++++ EE K ++ + ++CE I + R+ P+ P + Sbjct: 843 QKE---AERKKKEEEE----------KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQ 889 Query: 213 KKSKNKQRNTGDIQKYLTPKSQFGSASHSEA 243 K +K + + + S S +++ Sbjct: 890 NKIASKLQRPPSVDSIIRSFIHESSMSRAQS 920 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.126 0.361 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,822,836 Number of Sequences: 37866 Number of extensions: 1209720 Number of successful extensions: 17207 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 509 Number of HSP's successfully gapped in prelim test: 819 Number of HSP's that attempted gapping in prelim test: 7626 Number of HSP's gapped (non-prelim): 5423 length of query: 571 length of database: 18,247,518 effective HSP length: 108 effective length of query: 463 effective length of database: 14,157,990 effective search space: 6555149370 effective search space used: 6555149370 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.