Search of human proteins with 31083259

Search of human proteins with 31083259

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31083259 gamma isoform of regulatory subunit B56, protein
phosphatase 2A isoform a [Homo sapiens]
         (524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31083259 gamma isoform of regulatory subunit B56, protein pho...  1061   0.0  
gi|240849353 gamma isoform of regulatory subunit B56, protein ph...  1002   0.0  
gi|31083236 gamma isoform of regulatory subunit B56, protein pho...   966   0.0  
gi|240849359 gamma isoform of regulatory subunit B56, protein ph...   906   0.0  
gi|31083243 gamma isoform of regulatory subunit B56, protein pho...   898   0.0  
gi|5453954 delta isoform of regulatory subunit B56, protein phos...   828   0.0  
gi|31083280 delta isoform of regulatory subunit B56, protein pho...   822   0.0  
gi|31083288 delta isoform of regulatory subunit B56, protein pho...   821   0.0  
gi|5453956 epsilon isoform of regulatory subunit B56, protein ph...   615   e-176
gi|5453950 protein phosphatase 2, regulatory subunit B (B56), al...   612   e-175
gi|5453952 beta isoform of regulatory subunit B56, protein phosp...   591   e-169
gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens]              34   0.37 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    33   0.83 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    33   0.83 
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    32   1.1  
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    32   1.1  
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    32   1.1  
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    32   1.1  
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]    32   1.1  
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]    32   1.1  
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]     32   1.1  
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]    32   1.1  
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi...    32   1.1  
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            32   1.9  
gi|222080092 WD repeat domain 91 [Homo sapiens]                        31   2.4  
gi|112734867 retinitis pigmentosa GTPase regulator interacting p...    31   2.4  
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     30   4.1  
gi|110611228 utrophin [Homo sapiens]                                   30   4.1  
gi|163792208 Rho guanine exchange factor 16 [Homo sapiens]             30   5.4  
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    30   7.0  

>gi|31083259 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform a [Homo sapiens]
          Length = 524

 Score = 1061 bits (2745), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH 480
           LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH
Sbjct: 421 LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH 480

Query: 481 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 524
           QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 481 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 524


>gi|240849353 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform e [Homo sapiens]
          Length = 555

 Score = 1002 bits (2590), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 31  RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
           RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP
Sbjct: 62  RDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 121

Query: 91  IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 150
           IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF
Sbjct: 122 IYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDF 181

Query: 151 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 210
           QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR
Sbjct: 182 QPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYR 241

Query: 211 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 270
           FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC
Sbjct: 242 FIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYC 301

Query: 271 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 330
           VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ
Sbjct: 302 VVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQ 361

Query: 331 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 390
           LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI
Sbjct: 362 LAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLI 421

Query: 391 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 450
           YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS
Sbjct: 422 YNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQAS 481

Query: 451 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 510
           TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE
Sbjct: 482 TMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALE 541

Query: 511 AHCRADELASQDGR 524
           AHCRADELASQDGR
Sbjct: 542 AHCRADELASQDGR 555


>gi|31083236 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform b [Homo sapiens]
          Length = 485

 Score =  966 bits (2497), Expect = 0.0
 Identities = 485/524 (92%), Positives = 485/524 (92%), Gaps = 39/524 (7%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH 480
           LKMKEREEAWVKIENLAKANP                                       
Sbjct: 421 LKMKEREEAWVKIENLAKANP--------------------------------------- 441

Query: 481 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 524
           QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 442 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 485


>gi|240849359 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform f [Homo sapiens]
          Length = 540

 Score =  906 bits (2342), Expect = 0.0
 Identities = 458/510 (89%), Positives = 463/510 (90%), Gaps = 41/510 (8%)

Query: 15  AANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS 74
           +A++N   Q   L  ++DVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS
Sbjct: 72  SASNNRELQK--LPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALS 129

Query: 75  EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL 134
           EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL
Sbjct: 130 EMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHL 189

Query: 135 QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL 194
           QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL
Sbjct: 190 QLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFL 249

Query: 195 GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL 254
           GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL
Sbjct: 250 GLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL 309

Query: 255 HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV 314
           HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV
Sbjct: 310 HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDV 369

Query: 315 IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL 374
           IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL
Sbjct: 370 IEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSL 429

Query: 375 YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE 434
           YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE
Sbjct: 430 YRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIE 489

Query: 435 NLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLAR 494
           NLAKANP                                       QAQKDPKKDRPLAR
Sbjct: 490 NLAKANP---------------------------------------QAQKDPKKDRPLAR 510

Query: 495 RKSELPQDPHTKKALEAHCRADELASQDGR 524
           RKSELPQDPHTKKALEAHCRADELASQDGR
Sbjct: 511 RKSELPQDPHTKKALEAHCRADELASQDGR 540


>gi|31083243 gamma isoform of regulatory subunit B56, protein
           phosphatase 2A isoform c [Homo sapiens]
          Length = 449

 Score =  898 bits (2320), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60
           MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
Sbjct: 1   MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 60

Query: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120
           SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
Sbjct: 61  SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 120

Query: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180
           EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
Sbjct: 121 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 180

Query: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240
           FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
Sbjct: 181 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 240

Query: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300
           EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
Sbjct: 241 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 300

Query: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360
           EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
Sbjct: 301 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 360

Query: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420
           DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
Sbjct: 361 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 420

Query: 421 LKMKEREEAWVKIENLAKANPQ 442
           LKMKEREEAWVKIENLAKANPQ
Sbjct: 421 LKMKEREEAWVKIENLAKANPQ 442


>gi|5453954 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 1 [Homo sapiens]
          Length = 602

 Score =  828 bits (2138), Expect = 0.0
 Identities = 404/495 (81%), Positives = 451/495 (91%), Gaps = 2/495 (0%)

Query: 30  IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 89
           ++D P  ++E+LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE
Sbjct: 106 LKDSPTQEREELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTE 165

Query: 90  PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 149
            IYPE V MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD
Sbjct: 166 AIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 225

Query: 150 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 209
           FQPNIAKKYIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFY
Sbjct: 226 FQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFY 285

Query: 210 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 269
           RFIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAY
Sbjct: 286 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAY 345

Query: 270 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 329
           CVVQFLEK+S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFR
Sbjct: 346 CVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFR 405

Query: 330 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 389
           QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGL
Sbjct: 406 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGL 465

Query: 390 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQA 449
           IYNALKLFMEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE LA+ NPQY ++   
Sbjct: 466 IYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAP 525

Query: 450 STMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKAL 509
             +    +MET+ P  ED+Q+L++TV+ EA Q  KD KK++ L RRKSELPQD +T KAL
Sbjct: 526 PPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKAL 585

Query: 510 EAHCRADEL--ASQD 522
           EAH RA+E   ASQ+
Sbjct: 586 EAHKRAEEFLTASQE 600


>gi|31083280 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 2 [Homo sapiens]
          Length = 570

 Score =  822 bits (2123), Expect = 0.0
 Identities = 405/509 (79%), Positives = 453/509 (88%), Gaps = 2/509 (0%)

Query: 16  ANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSE 75
           +NS  P   +  +     P   +++LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+E
Sbjct: 60  SNSTPPPTQLSKIKYSGGPQIVKKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNE 119

Query: 76  MVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ 135
           MVEYITH+R+V+TE IYPE V MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ
Sbjct: 120 MVEYITHSRDVVTEAIYPEAVTMFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQ 179

Query: 136 LVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLG 195
           LVYEFFLRFLESPDFQPNIAKKYIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLG
Sbjct: 180 LVYEFFLRFLESPDFQPNIAKKYIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLG 239

Query: 196 LRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLH 255
           LRAYIR+QIN+IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLH
Sbjct: 240 LRAYIRRQINHIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLH 299

Query: 256 KVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVI 315
           KVKSLSVYHPQLAYCVVQFLEK+S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVI
Sbjct: 300 KVKSLSVYHPQLAYCVVQFLEKESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVI 359

Query: 316 EPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLY 375
           EPSEF K+MEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LY
Sbjct: 360 EPSEFSKVMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALY 419

Query: 376 RNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN 435
           RNSK+HWNKTIHGLIYNALKLFMEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE 
Sbjct: 420 RNSKSHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEE 479

Query: 436 LAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARR 495
           LA+ NPQY ++     +    +MET+ P  ED+Q+L++TV+ EA Q  KD KK++ L RR
Sbjct: 480 LARLNPQYPMFRAPPPLPPVYSMETETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRR 539

Query: 496 KSELPQDPHTKKALEAHCRADEL--ASQD 522
           KSELPQD +T KALEAH RA+E   ASQ+
Sbjct: 540 KSELPQDVYTIKALEAHKRAEEFLTASQE 568


>gi|31083288 delta isoform of regulatory subunit B56, protein
           phosphatase 2A isoform 3 [Homo sapiens]
          Length = 496

 Score =  821 bits (2120), Expect = 0.0
 Identities = 401/487 (82%), Positives = 446/487 (91%), Gaps = 2/487 (0%)

Query: 38  QEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVH 97
           +++LFIQKLRQCCVLFDFVSDPLSDLK+KEVKRA L+EMVEYITH+R+V+TE IYPE V 
Sbjct: 8   EKELFIQKLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVT 67

Query: 98  MFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 157
           MF+VN+FRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK
Sbjct: 68  MFSVNLFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKK 127

Query: 158 YIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEH 217
           YIDQKFVL LL+LFDSEDPRERDFLKT LHRIYGKFLGLRAYIR+QIN+IFYRFIYETEH
Sbjct: 128 YIDQKFVLALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEH 187

Query: 218 HNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEK 277
           HNGIAELLEILGSIINGFALPLKEEHK+FL++VLLPLHKVKSLSVYHPQLAYCVVQFLEK
Sbjct: 188 HNGIAELLEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEK 247

Query: 278 DSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSS 337
           +S+LTEPV++ LLK+WPKTHSPKEVMFLNELEEILDVIEPSEF K+MEPLFRQLAKCVSS
Sbjct: 248 ESSLTEPVIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSS 307

Query: 338 PHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLF 397
           PHFQVAERALYYWNNEYIMSLISDNAA++LPIMFP+LYRNSK+HWNKTIHGLIYNALKLF
Sbjct: 308 PHFQVAERALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLF 367

Query: 398 MEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVA 457
           MEMNQKLFDDCTQQ+KAEK K + +MKEREE W KIE LA+ NPQY ++     +    +
Sbjct: 368 MEMNQKLFDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAPPPLPPVYS 427

Query: 458 METDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADE 517
           MET+ P  ED+Q+L++TV+ EA Q  KD KK++ L RRKSELPQD +T KALEAH RA+E
Sbjct: 428 METETPTAEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEE 487

Query: 518 L--ASQD 522
              ASQ+
Sbjct: 488 FLTASQE 494


>gi|5453956 epsilon isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 467

 Score =  615 bits (1586), Expect = e-176
 Identities = 300/416 (72%), Positives = 353/416 (84%), Gaps = 4/416 (0%)

Query: 21  PFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYI 80
           P +   L  ++DVP ++Q +LF++KL+QCCV+FDF+ D LSDLK KE KR+ L+E+V+YI
Sbjct: 42  PIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFM-DTLSDLKMKEYKRSTLNELVDYI 100

Query: 81  THNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEF 140
           T +R  +TE  YPEVV M + N+FRTLPPS +    EFDPEEDEPTLEA+WPHLQLVYEF
Sbjct: 101 TISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSN---EFDPEEDEPTLEASWPHLQLVYEF 157

Query: 141 FLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYI 200
           F+RFLES +FQP+IAKKYIDQKFVLQLLELFDSEDPRERD+LKT LHRIYGKFLGLRA+I
Sbjct: 158 FIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFI 217

Query: 201 RKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSL 260
           RKQINNIF RF+YETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+PLH V+SL
Sbjct: 218 RKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSL 277

Query: 261 SVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEF 320
           S++H QLAYC+VQFLEKD +LTEPV+  L+K+WPKT S KEVMFL ELEEILDVIEPS+F
Sbjct: 278 SLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQF 337

Query: 321 VKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKT 380
           VKI EPLF+Q+AKCVSSPHFQVAERALYYWNNEYIMSLI +N+  ILPIMF SLYR SK 
Sbjct: 338 VKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKE 397

Query: 381 HWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436
           HWN  I  L+YN LK FMEMN  +FD+ T  +K+++ +EK K KEREE W K+E+L
Sbjct: 398 HWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDL 453


>gi|5453950 protein phosphatase 2, regulatory subunit B (B56), alpha
           isoform [Homo sapiens]
          Length = 486

 Score =  612 bits (1577), Expect = e-175
 Identities = 302/433 (69%), Positives = 353/433 (81%), Gaps = 10/433 (2%)

Query: 27  LLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV 86
           L  ++D    +Q++LF QKL+QCC+LFDF+ D +SDLK KE+KRA L+E+VEY++ NR V
Sbjct: 56  LPQLKDATSNEQQELFCQKLQQCCILFDFM-DSVSDLKSKEIKRATLNELVEYVSTNRGV 114

Query: 87  ITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLE 146
           I E  Y ++V M + N+FRTLPPS NP   +FDPEEDEPTLEA+WPH+QLVYEFFLRFLE
Sbjct: 115 IVESAYSDIVKMISANIFRTLPPSDNP---DFDPEEDEPTLEASWPHIQLVYEFFLRFLE 171

Query: 147 SPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINN 206
           SPDFQP+IAK+YIDQKFV QLLELFDSEDPRERDFLKT LHRIYGKFLGLRA+IRKQINN
Sbjct: 172 SPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINN 231

Query: 207 IFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQ 266
           IF RFIYETEH NG+AELLEILGSIINGFALPLK EHK FL+KVL+P+H  K L+++H Q
Sbjct: 232 IFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQ 291

Query: 267 LAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEP 326
           LAYCVVQFLEKD+TLTEPV+  LLK+WPKT S KEVMFL E+EEILDVIEP++F KI EP
Sbjct: 292 LAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEP 351

Query: 327 LFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTI 386
           LF+Q++KCVSS HFQVAERALY+WNNEYI+SLI +N  KILPIMF SLY+ SK HWN TI
Sbjct: 352 LFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTI 411

Query: 387 HGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIEN------LAKAN 440
             L+YN LK  MEMN KLFDD T  +KAE+ +EK K  EREE W K+E       L K N
Sbjct: 412 VALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQN 471

Query: 441 PQYTVYSQASTMS 453
             Y ++S  S  S
Sbjct: 472 SAYNMHSILSNTS 484


>gi|5453952 beta isoform of regulatory subunit B56, protein
           phosphatase 2A [Homo sapiens]
          Length = 497

 Score =  591 bits (1524), Expect = e-169
 Identities = 286/407 (70%), Positives = 342/407 (84%), Gaps = 4/407 (0%)

Query: 30  IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITE 89
           ++DVP ++  +L  +KL QC V+FDF+ D ++DLK KEVKRAAL+E+VE +   R V+ E
Sbjct: 65  LKDVPASELHELLSRKLAQCGVMFDFL-DCVADLKGKEVKRAALNELVECVGSTRGVLIE 123

Query: 90  PIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPD 149
           P+YP+++ M +VN+FRTLPPS NP   EFDPEEDEP LE +WPHLQLVYEFFLRFLESPD
Sbjct: 124 PVYPDIIRMISVNIFRTLPPSENP---EFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPD 180

Query: 150 FQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFY 209
           FQP++AK+Y+DQKFVL LLELFDSEDPRER++LKT LHR+YGKFLGLRAYIRKQ N+IF 
Sbjct: 181 FQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFL 240

Query: 210 RFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAY 269
           RFIYE EH NG+AELLEILGSIINGFALPLK EHK FL++VL+PLH VKSLSV+H QLAY
Sbjct: 241 RFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAY 300

Query: 270 CVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFR 329
           CVVQFLEKD+TLTE V+  LLKYWPKT + KEVMFL E+EEILDVIEPS+FVKI EPLF+
Sbjct: 301 CVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFK 360

Query: 330 QLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGL 389
           Q+A+CVSSPHFQVAERALY+WNNEYI+SLI DN   +LP +F +LY+ SK HWN+TI  L
Sbjct: 361 QVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSL 420

Query: 390 IYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENL 436
           IYN LK FMEMN KLFD+ T  +K EK +E+ K +ER+E W  +E L
Sbjct: 421 IYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEEL 467


>gi|4505727 peroxisomal biogenesis factor 3 [Homo sapiens]
          Length = 373

 Score = 33.9 bits (76), Expect = 0.37
 Identities = 33/163 (20%), Positives = 77/163 (47%), Gaps = 18/163 (11%)

Query: 219 NGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKD 278
           +G+ EL+ ++   +      +  +H + LL +   L ++++L   H   ++     + KD
Sbjct: 174 DGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSW-----INKD 228

Query: 279 STLTEPVVMALLKYWPKTH--------SPKEVMFLNELEEILDVIEPSEFVKIMEP-LFR 329
            +  +P++   +    +T         SP+++  +  L E  D++E  +F  ++   L R
Sbjct: 229 GS--KPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNR 286

Query: 330 QLAKCVSS--PHFQVAERALYYWNNEYIMSLISDNAAKILPIM 370
             ++ + +    F+  E+ L + N+   +S +S   AKI+PI+
Sbjct: 287 GFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIV 329


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 71/291 (24%), Positives = 118/291 (40%), Gaps = 51/291 (17%)

Query: 235  FALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWP 294
            F  P K E +I  LK  +   K K LS    +      +     S  T    M   +Y P
Sbjct: 790  FVPPEKHEKEIIALKSNIVELK-KQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVP 848

Query: 295  -KTHSPKEVMFLNEL----EEILDVIEP-----SEFVKIM---EPLFRQLAKC---VSSP 338
             KTH   ++   + L     E+LDV +       EFVKI    E L R L      + + 
Sbjct: 849  VKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAE 908

Query: 339  HFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFM 398
            +  +AE      +    M  + D+ A+IL     + YR  +     T+H  I  A K  +
Sbjct: 909  YISLAEHEAKMSSLSQSMRKVQDSNAEIL-----ANYRKGQEEI-VTLHAEI-KAQKKEL 961

Query: 399  EMNQKL----------FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQ 448
            +  Q+           F++C ++FKA + + K ++ E+ + +   E   K N Q      
Sbjct: 962  DTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQ------ 1015

Query: 449  ASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSEL 499
                      E D  L +++  L+K ++D+    +K  + +R L+R+  EL
Sbjct: 1016 ----------END-KLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDEL 1055


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 32.7 bits (73), Expect = 0.83
 Identities = 71/291 (24%), Positives = 118/291 (40%), Gaps = 51/291 (17%)

Query: 235  FALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWP 294
            F  P K E +I  LK  +   K K LS    +      +     S  T    M   +Y P
Sbjct: 803  FVPPEKHEKEIIALKSNIVELK-KQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVP 861

Query: 295  -KTHSPKEVMFLNEL----EEILDVIEP-----SEFVKIM---EPLFRQLAKC---VSSP 338
             KTH   ++   + L     E+LDV +       EFVKI    E L R L      + + 
Sbjct: 862  VKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAE 921

Query: 339  HFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFM 398
            +  +AE      +    M  + D+ A+IL     + YR  +     T+H  I  A K  +
Sbjct: 922  YISLAEHEAKMSSLSQSMRKVQDSNAEIL-----ANYRKGQEEI-VTLHAEI-KAQKKEL 974

Query: 399  EMNQKL----------FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQ 448
            +  Q+           F++C ++FKA + + K ++ E+ + +   E   K N Q      
Sbjct: 975  DTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQ------ 1028

Query: 449  ASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSEL 499
                      E D  L +++  L+K ++D+    +K  + +R L+R+  EL
Sbjct: 1029 ----------END-KLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDEL 1068


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 442 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 497
           Q TV+   S   +P+   T GP  E +Q L K     ++ E  +A+   K++    +R+ 
Sbjct: 694 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 753

Query: 498 EL 499
           EL
Sbjct: 754 EL 755


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 442 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 497
           Q TV+   S   +P+   T GP  E +Q L K     ++ E  +A+   K++    +R+ 
Sbjct: 721 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 780

Query: 498 EL 499
           EL
Sbjct: 781 EL 782


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 442 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 497
           Q TV+   S   +P+   T GP  E +Q L K     ++ E  +A+   K++    +R+ 
Sbjct: 700 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 759

Query: 498 EL 499
           EL
Sbjct: 760 EL 761


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 442 QYTVYSQASTMSIPVAMETDGPLFEDVQMLRKT----VKDEAHQAQKDPKKDRPLARRKS 497
           Q TV+   S   +P+   T GP  E +Q L K     ++ E  +A+   K++    +R+ 
Sbjct: 700 QPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQE 759

Query: 498 EL 499
           EL
Sbjct: 760 EL 761


>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
          Length = 611

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)

Query: 425 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 482
           ER +A V+   LA+A P   V S      +PV A    GP + EDV       K +  Q 
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482

Query: 483 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 509
           Q          +  K+  LAR   E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)

Query: 425 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 482
           ER +A V+   LA+A P   V S      +PV A    GP + EDV       K +  Q 
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482

Query: 483 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 509
           Q          +  K+  LAR   E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517


>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
          Length = 633

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)

Query: 425 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 482
           ER +A V+   LA+A P   V S      +PV A    GP + EDV       K +  Q 
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482

Query: 483 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 509
           Q          +  K+  LAR   E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)

Query: 425 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 482
           ER +A V+   LA+A P   V S      +PV A    GP + EDV       K +  Q 
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482

Query: 483 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 509
           Q          +  K+  LAR   E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517


>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
           sapiens]
          Length = 560

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 12/96 (12%)

Query: 425 EREEAWVKIENLAKANPQYTVYSQASTMSIPV-AMETDGPLF-EDVQMLRKTVKDEAHQA 482
           ER +A V+   LA+A P   V S      +PV A    GP + EDV       K +  Q 
Sbjct: 423 ERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQT 482

Query: 483 Q---------KDPKKDRPLARRKSELPQDPHTKKAL 509
           Q          +  K+  LAR   E P+ P T KA+
Sbjct: 483 QCPRKVIKMESEEGKEARLARSSPEQPR-PSTSKAV 517


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 420 KLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEA 479
           +LK ++  E  ++ +N    N  + V S         A+ETD  + E++       K + 
Sbjct: 544 ELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQ---AVETDEGIEEEIPDSPGIEKHDK 600

Query: 480 HQAQKDPKKDRPLARRKSELPQDPHTKKALE 510
            + QKDPKK R       +  +   TKK L+
Sbjct: 601 EKEQKDPKKLRSFKVSSIDSSEQKKTKKNLK 631


>gi|222080092 WD repeat domain 91 [Homo sapiens]
          Length = 747

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 36/137 (26%), Positives = 55/137 (40%), Gaps = 31/137 (22%)

Query: 36  ADQEKLF-----IQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEP 90
           AD+EK F     + +L+Q   ++D  +  L D  W  ++R   S +            E 
Sbjct: 34  ADKEKGFRVDKIVDQLQQLMQVYDLAA--LRDY-WSYLERRLFSRL------------ED 78

Query: 91  IYPEVVHMFAVNMFR-----TLPPSSNPTGAEFDPEE-DEPTLEAAWPHLQLVYEFFLRF 144
           IY   +H    ++FR     T+  + N    EF  ++  E   +A W        F L F
Sbjct: 79  IYRPTIHKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDW-----FVLPF 133

Query: 145 LESPDFQPNIAKKYIDQ 161
           L SPD  P  A  +  Q
Sbjct: 134 LPSPDTNPTFATYFSRQ 150


>gi|112734867 retinitis pigmentosa GTPase regulator interacting
           protein 1 [Homo sapiens]
          Length = 1286

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 9/165 (5%)

Query: 358 LISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKL 417
           L++DN  K+L  M  S   +S+ HW+   + LI   L+  +   Q   D   +  +   L
Sbjct: 373 LLNDNYDKLLESMLDSSDSSSQPHWS---NELIAEQLQQQVSQLQDQLDAELEDKRKVLL 429

Query: 418 KEKLKMKEREEAWVKIEN-LAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVK 476
           +   +  + E+  +++ N L K   +  +   A+T+S P   +++ P      +   T  
Sbjct: 430 ELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSE-PATHPAVLQENTQI 488

Query: 477 DEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQ 521
           + +    ++ KK   L++  +EL Q  H +  LE     D L  Q
Sbjct: 489 EPSEPKNQEEKK---LSQVLNEL-QVSHAETTLELEKTRDMLILQ 529


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 9/102 (8%)

Query: 414 AEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRK 473
           A+K  EK K   +EE    +++  KA       ++A    IP   E   P+ E+ +    
Sbjct: 778 ADKFPEKAKSPVKEE----VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833

Query: 474 TVKDEAHQAQKD-----PKKDRPLARRKSELPQDPHTKKALE 510
            VK+   +A+++     PK +     +K E P+    K  +E
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 249  KVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKE 301
            KVL    + K     HP+L Y  VQ + +   L  P+   L+  WP+ + P +
Sbjct: 3131 KVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPI--TLISMWPEHYDPSQ 3181


>gi|163792208 Rho guanine exchange factor 16 [Homo sapiens]
          Length = 709

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 212 IYETEHHNGIAELLEILGSIINGFALPLKEEHKI-FLLKVLLPLHKVKSLSVYHPQLAYC 270
           + + EHH+  + +L++LG+    F   L++ HK   L++ +  + +  +   +HP +AYC
Sbjct: 320 VTQMEHHHLFSNILDVLGA-SQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYC 378


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 3/111 (2%)

Query: 410 QQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPL--FED 467
           +Q   E+ K+K K K +E+  VK +   K   + T Y     +    A      +  FED
Sbjct: 538 KQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFED 597

Query: 468 VQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADEL 518
           V    K +KD   + +K+  KD+   R K +  +D   K+ ++   R D++
Sbjct: 598 VDPKVK-LKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKM 647


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,666,086
Number of Sequences: 37866
Number of extensions: 871096
Number of successful extensions: 2957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2929
Number of HSP's gapped (non-prelim): 51
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.