BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|30794372 polybromo 1 isoform 1 [Homo sapiens] (1602 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 3254 0.0 gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 3093 0.0 gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 3003 0.0 gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 103 1e-21 gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 103 1e-21 gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 100 1e-20 gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20 gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20 gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20 gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 99 3e-20 gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 99 3e-20 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 90 2e-17 gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 86 4e-16 gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 84 1e-15 gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 84 1e-15 gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 81 7e-15 gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 75 7e-13 gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 75 7e-13 gi|34996489 pleckstrin homology domain interacting protein [Homo... 74 1e-12 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 67 2e-10 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 67 2e-10 gi|46399200 testis-specific bromodomain protein [Homo sapiens] 64 1e-09 gi|46399198 testis-specific bromodomain protein [Homo sapiens] 64 1e-09 gi|164419758 bromodomain containing 2 [Homo sapiens] 63 3e-09 gi|4826806 bromodomain containing 2 [Homo sapiens] 63 3e-09 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 62 6e-09 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 61 8e-09 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 61 8e-09 gi|7706501 WW domain binding protein 11 [Homo sapiens] 61 8e-09 gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 60 1e-08 >gi|30794372 polybromo 1 isoform 1 [Homo sapiens] Length = 1602 Score = 3254 bits (8436), Expect = 0.0 Identities = 1602/1602 (100%), Positives = 1602/1602 (100%) Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS 300 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS 300 Query: 301 NKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT 360 NKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT Sbjct: 301 NKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT 360 Query: 361 VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDL 420 VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDL Sbjct: 361 VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDL 420 Query: 421 NLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKR 480 NLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKR Sbjct: 421 NLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKR 480 Query: 481 KSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE 540 KSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE Sbjct: 481 KSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE 540 Query: 541 HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD 600 HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD Sbjct: 541 HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD 600 Query: 601 DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSE 660 DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSE Sbjct: 601 DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSE 660 Query: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 720 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL Sbjct: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 720 Query: 721 HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP 780 HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP Sbjct: 721 HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP 780 Query: 781 NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF 840 NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF Sbjct: 781 NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF 840 Query: 841 IKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE 900 IKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE Sbjct: 841 IKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE 900 Query: 901 DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW 960 DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW Sbjct: 901 DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW 960 Query: 961 LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFR 1020 LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFR Sbjct: 961 LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFR 1020 Query: 1021 DEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN 1080 DEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN Sbjct: 1021 DEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN 1080 Query: 1081 TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV 1140 TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV Sbjct: 1081 TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV 1140 Query: 1141 RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGK 1200 RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGK Sbjct: 1141 RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGK 1200 Query: 1201 CAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR 1260 CAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR Sbjct: 1201 CAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR 1260 Query: 1261 KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE 1320 KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE Sbjct: 1261 KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE 1320 Query: 1321 LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRL 1380 LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRL Sbjct: 1321 LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRL 1380 Query: 1381 VGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGV 1440 VGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGV Sbjct: 1381 VGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGV 1440 Query: 1441 PGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQ 1500 PGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQ Sbjct: 1441 PGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQ 1500 Query: 1501 QPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESR 1560 QPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESR Sbjct: 1501 QPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESR 1560 Query: 1561 LPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1602 LPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV Sbjct: 1561 LPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV 1602 >gi|93102371 polybromo 1 isoform 2 [Homo sapiens] Length = 1582 Score = 3093 bits (8020), Expect = 0.0 Identities = 1549/1634 (94%), Positives = 1549/1634 (94%), Gaps = 84/1634 (5%) Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS 300 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRM Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300 Query: 301 --------------------------------NKRAVQGGRLSAITMALQYGSESEEDAA 328 NKRAVQGGRLSAITMALQYGSESEEDAA Sbjct: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360 Query: 329 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 388 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY Sbjct: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420 Query: 389 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 448 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM Sbjct: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480 Query: 449 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 508 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR Sbjct: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540 Query: 509 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 568 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY Sbjct: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600 Query: 569 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 628 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ Sbjct: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660 Query: 629 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 688 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD Sbjct: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720 Query: 689 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 748 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE Sbjct: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780 Query: 749 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 808 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF Sbjct: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840 Query: 809 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 868 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN Sbjct: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900 Query: 869 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 928 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV Sbjct: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960 Query: 929 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 988 GDYVYVEPAEANLQPHIVCIERLWEDSA EKEVFKS Sbjct: 961 GDYVYVEPAEANLQPHIVCIERLWEDSA-------------------------EKEVFKS 995 Query: 989 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1048 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI Sbjct: 996 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1055 Query: 1049 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1108 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN Sbjct: 1056 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1115 Query: 1109 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1168 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE Sbjct: 1116 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1175 Query: 1169 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1228 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR Sbjct: 1176 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1235 Query: 1229 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1288 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE Sbjct: 1236 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1295 Query: 1289 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1348 GGDDDIEEMGEEDSE STPKSAKGSAKKEGSKRK Sbjct: 1296 GGDDDIEEMGEEDSE---------------------------STPKSAKGSAKKEGSKRK 1328 Query: 1349 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1408 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP Sbjct: 1329 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1388 Query: 1409 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1468 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS Sbjct: 1389 PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS 1448 Query: 1469 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1528 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE Sbjct: 1449 PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIE 1508 Query: 1529 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1588 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR Sbjct: 1509 GLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLR 1568 Query: 1589 DTLNIRQAYNLENV 1602 DTLNIRQAYNLENV Sbjct: 1569 DTLNIRQAYNLENV 1582 >gi|41281917 polybromo 1 isoform 4 [Homo sapiens] Length = 1582 Score = 3003 bits (7786), Expect = 0.0 Identities = 1519/1635 (92%), Positives = 1523/1635 (93%), Gaps = 86/1635 (5%) Query: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY Sbjct: 1 MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDY 60 Query: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF Sbjct: 61 KDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLF 120 Query: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA Sbjct: 121 NNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA 180 Query: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG Sbjct: 181 YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNG 240 Query: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMS 300 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRM Sbjct: 241 SYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMR 300 Query: 301 --------------------------------NKRAVQGGRLSAITMALQYGSESEEDAA 328 NKRAVQGGRLSAITMALQYGSESEEDAA Sbjct: 301 TPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA 360 Query: 329 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 388 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY Sbjct: 361 LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDY 420 Query: 389 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 448 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM Sbjct: 421 YQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVM 480 Query: 449 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 508 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR Sbjct: 481 QAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR 540 Query: 509 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 568 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY Sbjct: 541 RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHY 600 Query: 569 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 628 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ Sbjct: 601 NEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQ 660 Query: 629 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 688 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD Sbjct: 661 KLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD 720 Query: 689 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 748 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE Sbjct: 721 IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQE 780 Query: 749 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 808 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF Sbjct: 781 LIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLF 840 Query: 809 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 868 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN Sbjct: 841 QEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN 900 Query: 869 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 928 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV Sbjct: 901 DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHV 960 Query: 929 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 988 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS Sbjct: 961 GDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKS 1020 Query: 989 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1048 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI Sbjct: 1021 DYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1080 Query: 1049 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1108 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN Sbjct: 1081 SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN 1140 Query: 1109 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1168 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE Sbjct: 1141 GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPE 1200 Query: 1169 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1228 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR Sbjct: 1201 ETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR 1260 Query: 1229 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1288 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE Sbjct: 1261 YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE 1320 Query: 1289 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1348 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK Sbjct: 1321 GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRK 1380 Query: 1349 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP 1408 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEG+M G+ Sbjct: 1381 INMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMN---QGVA 1437 Query: 1409 PLQG-PVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGG 1467 P+ G P G G Q + GPP PP PG P P G Sbjct: 1438 PMVGTPAPGGSPYG--QQVGVLGPPGQQAPPPYPG--------------------PHPAG 1475 Query: 1468 SPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYI 1527 P QQ PTTPMFVAPPPKTQRLLHSEAYLKYI Sbjct: 1476 PPVIQQ----------------------------PTTPMFVAPPPKTQRLLHSEAYLKYI 1507 Query: 1528 EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML 1587 EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML Sbjct: 1508 EGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML 1567 Query: 1588 RDTLNIRQAYNLENV 1602 RDTLNIRQAYNLENV Sbjct: 1568 RDTLNIRQAYNLENV 1582 >gi|192807320 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform F [Homo sapiens] Length = 1613 Score = 103 bits (257), Expect = 1e-21 Identities = 57/177 (32%), Positives = 97/177 (54%), Gaps = 9/177 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1360 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1419 Query: 623 MTP--MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSH 680 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1479 Query: 681 MMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1480 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1536 Score = 96.7 bits (239), Expect = 2e-19 Identities = 53/195 (27%), Positives = 109/195 (55%), Gaps = 7/195 (3%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKV 215 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1399 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRK 1458 Query: 216 QYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANS 275 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1459 ELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIV 1518 Query: 276 IKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALAA 331 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1519 LQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGG 1578 Query: 332 ARYEEGESEAESITS 346 R S A+ + S Sbjct: 1579 RRRPSRGSRAKPVVS 1593 Score = 87.4 bits (215), Expect = 1e-16 Identities = 61/238 (25%), Positives = 117/238 (49%), Gaps = 10/238 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1366 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1419 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTK 404 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ + Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1479 Query: 405 LKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDG 464 ++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1480 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGE 1539 Query: 465 DSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1540 ESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1594 Score = 87.0 bits (214), Expect = 1e-16 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 16/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1366 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1425 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1426 TKKMKKIVDAVIKYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1484 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1485 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1544 Query: 608 KLSRKSG 614 + + G Sbjct: 1545 EEGEEEG 1551 Score = 80.1 bits (196), Expect = 2e-14 Identities = 48/170 (28%), Positives = 86/170 (50%), Gaps = 6/170 (3%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRL 67 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1389 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSGRQ 1446 Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1447 LSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFN 1506 Query: 128 KPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1507 LEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1552 Score = 52.8 bits (125), Expect = 3e-06 Identities = 38/166 (22%), Positives = 80/166 (48%), Gaps = 19/166 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 795 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I++ Sbjct: 1423 PNLTKKMKKIVD----AVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1478 Query: 796 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 855 + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1479 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD--- 1535 Query: 856 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1536 --------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1573 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|192807316 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform D [Homo sapiens] Length = 1616 Score = 103 bits (257), Expect = 1e-21 Identities = 57/177 (32%), Positives = 97/177 (54%), Gaps = 9/177 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1363 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1422 Query: 623 MTP--MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSH 680 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1482 Query: 681 MMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1483 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1539 Score = 96.7 bits (239), Expect = 2e-19 Identities = 53/195 (27%), Positives = 109/195 (55%), Gaps = 7/195 (3%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKV 215 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1402 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRK 1461 Query: 216 QYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANS 275 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1462 ELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIV 1521 Query: 276 IKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALAA 331 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1522 LQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGG 1581 Query: 332 ARYEEGESEAESITS 346 R S A+ + S Sbjct: 1582 RRRPSRGSRAKPVVS 1596 Score = 87.4 bits (215), Expect = 1e-16 Identities = 61/238 (25%), Positives = 117/238 (49%), Gaps = 10/238 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1369 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1422 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTK 404 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ + Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKER 1482 Query: 405 LKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDG 464 ++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1483 IRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGE 1542 Query: 465 DSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1543 ESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1597 Score = 87.0 bits (214), Expect = 1e-16 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 16/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1369 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1428 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1429 TKKMKKIVDAVIKYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1487 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1488 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1547 Query: 608 KLSRKSG 614 + + G Sbjct: 1548 EEGEEEG 1554 Score = 80.1 bits (196), Expect = 2e-14 Identities = 48/170 (28%), Positives = 86/170 (50%), Gaps = 6/170 (3%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRL 67 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1392 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSGRQ 1449 Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1450 LSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFN 1509 Query: 128 KPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1510 LEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1555 Score = 52.8 bits (125), Expect = 3e-06 Identities = 38/166 (22%), Positives = 80/166 (48%), Gaps = 19/166 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 795 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I++ Sbjct: 1426 PNLTKKMKKIVD----AVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1481 Query: 796 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 855 + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1482 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD--- 1538 Query: 856 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1539 --------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1576 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|48255898 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b [Homo sapiens] Length = 1572 Score = 100 bits (248), Expect = 1e-20 Identities = 50/153 (32%), Positives = 92/153 (60%), Gaps = 6/153 (3%) Query: 587 KEKRKELGPLPDDDDMASPKLKLSRKSG--ISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 644 +++R+ + P +D+ K + R +SP K + +++N + + V NY D Sbjct: 1346 RKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPK----LTKQMNAIIDTVINYKDSS 1401 Query: 645 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 704 GR+LS +F++LPSR ELP+YY I+KP+D +KI+ + +KY+ + + +D +++ +NA Sbjct: 1402 GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQ 1461 Query: 705 TYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 T+N S IY+D++VL V R+ + +E+S Sbjct: 1462 TFNLEGSQIYEDSIVLQSVFKSARQKIAKEEES 1494 Score = 92.0 bits (227), Expect = 4e-18 Identities = 60/202 (29%), Positives = 105/202 (51%), Gaps = 33/202 (16%) Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIVVATNPSGR 202 R R V K A ++D E + +G +P L + + +++ ++ + SGR Sbjct: 1346 RKRRRNVDKDPA--KEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGR 1403 Query: 203 LISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTY 262 +SE+F +LPS+ + P+YY +I++P+D K I +RI+N Y+S+ + KD+ LL NA+T+ Sbjct: 1404 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTF 1463 Query: 263 NEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSE 322 N GSQ+++D+ ++ +F + +I E ++ SN+ E Sbjct: 1464 NLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDE---SNE------------------EE 1502 Query: 323 SEEDAALAAARYEEGESEAESI 344 EED EE ESEA+S+ Sbjct: 1503 EEEDE-------EESESEAKSV 1517 Score = 89.7 bits (221), Expect = 2e-17 Identities = 46/168 (27%), Positives = 97/168 (57%), Gaps = 6/168 (3%) Query: 357 LYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHL 416 + DTV + +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L L Sbjct: 1390 IIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDL 1449 Query: 417 ECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTG 476 E D+ L+ NA+ +N+ S IY+ + LQ V ++ ++++A+ ++ ED S + Sbjct: 1450 EKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED-----ESNEEEEE 1504 Query: 477 SAKRKSKKNIRKQRMKILFNVVLE-AREPGSGRRLCDLFMVKPSKKDY 523 + +S+ + ++KI N + R+ G G++ + KP D+ Sbjct: 1505 EDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDF 1552 Score = 86.3 bits (212), Expect = 2e-16 Identities = 47/162 (29%), Positives = 92/162 (56%), Gaps = 4/162 (2%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAK-RKSKKNIRK--QRMKILFNVVL 499 ++++ ++ KK++ R D + + A G K N K ++M + + V+ Sbjct: 1336 EMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVI 1395 Query: 500 EAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMK 559 ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN KY + +D+ Sbjct: 1396 NYKD-SSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVM 1454 Query: 560 LMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDD 601 L+ NA+ +N EGSQ+Y D+ +L+ + K R+++ + +D Sbjct: 1455 LLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED 1496 Score = 82.4 bits (202), Expect = 3e-15 Identities = 35/118 (29%), Positives = 74/118 (62%) Query: 53 LYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLL 112 + +T+ +YKD GR L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y + L Sbjct: 1390 IIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDL 1449 Query: 113 TADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQ 170 D LL +NA+++ S Y+ + L ++ R + ++ E++DE ++E+ ++++ Sbjct: 1450 EKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE 1507 Score = 54.3 bits (129), Expect = 9e-07 Identities = 38/169 (22%), Positives = 83/169 (49%), Gaps = 14/169 (8%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIRK 795 PN L +++ + + +V++++D GR S+ ++P+ P + + P+ F I++ Sbjct: 1378 PNPPKLTKQM-NAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1436 Query: 796 NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILL 855 + N++YR L ++ + + A+ N S+IYED++ LQ F R ++ K E Sbjct: 1437 RIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEE--- 1493 Query: 856 SPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSG 904 + + + E+E +E+ E + K+K + K++ + + G Sbjct: 1494 ------SEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG 1536 Score = 40.4 bits (93), Expect = 0.014 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 10/118 (8%) Query: 1406 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ-GVAPMVGTPA 1464 G+ + P+DG+ G ++ +H G + P PG+ PP M+Q M P+ Sbjct: 69 GMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMG--PPQSPMDQHSQGYMSPHPS 126 Query: 1465 PGGSP--YGQQVGVLGPPGQQAPPPYPGP-HPAGPPVIQQPTTPMFVAPPPKTQRLLH 1519 P G+P + GP Q PP PG P P + QP P P + LH Sbjct: 127 PLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNR----GPSPFSPVQLH 180 Score = 35.8 bits (81), Expect = 0.34 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 1444 PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP-PPYPGPHPAGP-PVIQQ 1501 P P P + + PAPGG P PP P P P P P P PV+Q Sbjct: 262 PSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQL 321 Query: 1502 PTTPMFVAPPPKTQRL 1517 ++P K Q L Sbjct: 322 QQKQSRISPIQKPQGL 337 Score = 32.7 bits (73), Expect = 2.9 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 20/72 (27%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHP---------------GGPPPHHLPPGVPG--LPGIP 1447 PG+ P Q P+D S G M P HP GGP P +PP PG +PG P Sbjct: 104 PGMGPPQSPMDQH-SQGYMSP-HPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDP 161 Query: 1448 PP-GVMNQGVAP 1458 N+G +P Sbjct: 162 QAMSQPNRGPSP 173 >gi|192807323 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform A [Homo sapiens] Length = 1679 Score = 99.0 bits (245), Expect = 3e-20 Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1425 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1484 Query: 623 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 679 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1485 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1544 Query: 680 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1545 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1602 Score = 92.8 bits (229), Expect = 2e-18 Identities = 53/196 (27%), Positives = 109/196 (55%), Gaps = 8/196 (4%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1464 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1523 Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1524 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1583 Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALA 330 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1584 VLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKG 1643 Query: 331 AARYEEGESEAESITS 346 R S A+ + S Sbjct: 1644 GRRRPSRGSRAKPVVS 1659 Score = 91.3 bits (225), Expect = 7e-18 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1431 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1490 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1491 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1550 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1551 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1610 Query: 608 KLSRKSG 614 + + G Sbjct: 1611 EEGEEEG 1617 Score = 82.8 bits (203), Expect = 2e-15 Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 11/239 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1431 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1484 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQ-GQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRT 403 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ Sbjct: 1485 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1544 Query: 404 KLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIED 463 +++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1545 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEG 1604 Query: 464 GDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1605 EESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1660 Score = 75.5 bits (184), Expect = 4e-13 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1454 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1511 Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1512 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1571 Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1572 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1618 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 794 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+ Sbjct: 1488 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1543 Query: 795 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 854 + + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1544 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1601 Query: 855 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1602 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1639 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|192807318 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform E [Homo sapiens] Length = 1614 Score = 99.0 bits (245), Expect = 3e-20 Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1360 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1419 Query: 623 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 679 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1479 Query: 680 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1480 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1537 Score = 92.8 bits (229), Expect = 2e-18 Identities = 53/196 (27%), Positives = 109/196 (55%), Gaps = 8/196 (4%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1399 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1458 Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1459 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1518 Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALA 330 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1519 VLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKG 1578 Query: 331 AARYEEGESEAESITS 346 R S A+ + S Sbjct: 1579 GRRRPSRGSRAKPVVS 1594 Score = 91.3 bits (225), Expect = 7e-18 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1366 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1425 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1426 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1485 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1486 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1545 Query: 608 KLSRKSG 614 + + G Sbjct: 1546 EEGEEEG 1552 Score = 82.8 bits (203), Expect = 2e-15 Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 11/239 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1366 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1419 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQ-GQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRT 403 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ Sbjct: 1420 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1479 Query: 404 KLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIED 463 +++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1480 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEG 1539 Query: 464 GDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1540 EESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1595 Score = 75.5 bits (184), Expect = 4e-13 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1389 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1446 Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1447 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1506 Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1507 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1553 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 794 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+ Sbjct: 1423 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1478 Query: 795 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 854 + + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1479 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1536 Query: 855 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1537 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1574 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|192807314 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform C [Homo sapiens] Length = 1617 Score = 99.0 bits (245), Expect = 3e-20 Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1363 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1422 Query: 623 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 679 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1482 Query: 680 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1483 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1540 Score = 92.8 bits (229), Expect = 2e-18 Identities = 53/196 (27%), Positives = 109/196 (55%), Gaps = 8/196 (4%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1402 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1461 Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1462 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1521 Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALA 330 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1522 VLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKG 1581 Query: 331 AARYEEGESEAESITS 346 R S A+ + S Sbjct: 1582 GRRRPSRGSRAKPVVS 1597 Score = 91.3 bits (225), Expect = 7e-18 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1369 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1428 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1429 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1488 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1489 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1548 Query: 608 KLSRKSG 614 + + G Sbjct: 1549 EEGEEEG 1555 Score = 82.8 bits (203), Expect = 2e-15 Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 11/239 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1369 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1422 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQ-GQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRT 403 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ Sbjct: 1423 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1482 Query: 404 KLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIED 463 +++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1483 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEG 1542 Query: 464 GDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1543 EESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1598 Score = 75.5 bits (184), Expect = 4e-13 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1392 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1449 Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1450 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1509 Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1510 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1556 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 794 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+ Sbjct: 1426 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1481 Query: 795 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 854 + + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1482 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1539 Query: 855 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1540 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1577 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|192807312 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 99.0 bits (245), Expect = 3e-20 Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1393 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1452 Query: 623 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 679 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512 Query: 680 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1570 Score = 92.8 bits (229), Expect = 2e-18 Identities = 53/196 (27%), Positives = 109/196 (55%), Gaps = 8/196 (4%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1432 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1491 Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1492 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1551 Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALA 330 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1552 VLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKG 1611 Query: 331 AARYEEGESEAESITS 346 R S A+ + S Sbjct: 1612 GRRRPSRGSRAKPVVS 1627 Score = 91.3 bits (225), Expect = 7e-18 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1399 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1458 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1459 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1518 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1519 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578 Query: 608 KLSRKSG 614 + + G Sbjct: 1579 EEGEEEG 1585 Score = 82.8 bits (203), Expect = 2e-15 Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 11/239 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1399 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1452 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQ-GQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRT 403 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512 Query: 404 KLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIED 463 +++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEG 1572 Query: 464 GDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1573 EESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1628 Score = 75.5 bits (184), Expect = 4e-13 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1422 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1479 Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1480 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1539 Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1540 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1586 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 794 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+ Sbjct: 1456 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1511 Query: 795 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 854 + + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1512 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1569 Query: 855 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1570 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1607 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|21071056 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 99.0 bits (245), Expect = 3e-20 Identities = 57/178 (32%), Positives = 97/178 (54%), Gaps = 10/178 (5%) Query: 570 EEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL-------KLSRKSGISPKKSKY 622 EEG+ + + +K KRK S + K +K G P + Sbjct: 1393 EEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLS 1452 Query: 623 MTP--MQQKLNEVYEAVKNYTDKR-GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRS 679 P + +K+ ++ +AV Y D GR+LS +F++LPSR ELP+YY I+KP+D +KI+ Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512 Query: 680 HMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + +KY+ ++ + +D +++ NA T+N SLIY+D++VL V R+ +E ++DS Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDS 1570 Score = 92.8 bits (229), Expect = 2e-18 Identities = 53/196 (27%), Positives = 109/196 (55%), Gaps = 8/196 (4%) Query: 159 DEDDDEDGQDNQGTVTE---GSSPAYLKEILEQLLEAIV-VATNPSGRLISELFQKLPSK 214 D+DD+ Q +G +P L + ++++++A++ + SGR +SE+F +LPS+ Sbjct: 1432 DKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSR 1491 Query: 215 VQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDAN 274 + P+YY +I++P+D K I +RI+N Y+S++ + KD+ LL +NA+T+N GS +++D+ Sbjct: 1492 KELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSI 1551 Query: 275 SIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLS---AITMALQYG-SESEEDAALA 330 ++ +F + +IE + ++ + + G S ++ + ++ G E +D Sbjct: 1552 VLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKG 1611 Query: 331 AARYEEGESEAESITS 346 R S A+ + S Sbjct: 1612 GRRRPSRGSRAKPVVS 1627 Score = 91.3 bits (225), Expect = 7e-18 Identities = 51/187 (27%), Positives = 102/187 (54%), Gaps = 15/187 (8%) Query: 443 KLQQVMQAKKKELARRDDIEDGDSMISSATS--DTGSAKRKSKKNIRK------------ 488 ++++ ++ KK R+ D + G S +++T D +K KK R Sbjct: 1399 EIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNL 1458 Query: 489 -QRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDK 547 ++MK + + V++ ++ SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN K Sbjct: 1459 TKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK 1518 Query: 548 YAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKL 607 Y + +D+ L+ +NA+ +N EGS +Y D+ +L+ + R+++ D + S + Sbjct: 1519 YRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEE 1578 Query: 608 KLSRKSG 614 + + G Sbjct: 1579 EEGEEEG 1585 Score = 82.8 bits (203), Expect = 2e-15 Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 11/239 (4%) Query: 286 EIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESIT 345 EIE K S R KR G + T + E + + + G AE ++ Sbjct: 1399 EIEEEVRQKKSSR-KRKRDSDAGSSTPTTSTRSRDKDDE-----SKKQKKRGRPPAEKLS 1452 Query: 346 -SFMDVSNPFYQLYDTVRSCRNNQ-GQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRT 403 + +++ ++ D V +++ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ Sbjct: 1453 PNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKE 1512 Query: 404 KLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIED 463 +++N +Y +L+ LE D+ L+ +NA+ +N+ S IY+ + LQ V + ++++ + DD E Sbjct: 1513 RIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEG 1572 Query: 464 GDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKD 522 +S + GS +S+ K ++K+ + R G RR KP D Sbjct: 1573 EESEEEEEGEEEGS---ESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSD 1628 Score = 75.5 bits (184), Expect = 4e-13 Identities = 48/171 (28%), Positives = 86/171 (50%), Gaps = 7/171 (4%) Query: 8 ATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQ-GR 66 +T +S+ S D DD G + N P + ++ + + YKD GR Sbjct: 1422 STPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTK--KMKKIVDAVIKYKDSSSGR 1479 Query: 67 LLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSY 126 L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y +N L D LL NA+++ Sbjct: 1480 QLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1539 Query: 127 YKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGS 177 S Y+ + L ++ R QK E +D+ + E+ ++ + EGS Sbjct: 1540 NLEGSLIYEDSIVLQSVFTSVR----QKIEKEDDSEGEESEEEEEGEEEGS 1586 Score = 50.1 bits (118), Expect = 2e-05 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 12/117 (10%) Query: 1402 GYPPGLPPLQGPVDGLVSMGSMQPLHPGGPP-----PHHLPPGVPGLPGIPPPGVMNQGV 1456 G PG P GP G +P GGP P +PPG+PG P PP +G Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEG- 287 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY---PGPHPAGPPVIQQPTTPMFVAP 1510 PM AP +P Q++ P G+ +P P P P PP Q P P AP Sbjct: 288 -PMANAAAPTSTP--QKLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP 341 Score = 48.1 bits (113), Expect = 7e-05 Identities = 38/167 (22%), Positives = 80/167 (47%), Gaps = 20/167 (11%) Query: 740 PNVTLLIQELIHNLFVSVMSHQDDE-GRCYSDSLAEIPAVD--PNFPN--KPPLTFDIIR 794 PN+T +++++ +V+ ++D GR S+ ++P+ P + + P+ F I+ Sbjct: 1456 PNLTKKMKKIVD----AVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIK 1511 Query: 795 KNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEIL 854 + + N++YR L+ ++ + + + A+ N S IYED++ LQ F +R ++ K + Sbjct: 1512 ERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD-- 1569 Query: 855 LSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSED 901 E+E E+ E E +K + + EK++D Sbjct: 1570 ---------SEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQD 1607 Score = 46.6 bits (109), Expect = 2e-04 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 23/118 (19%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P GP G PG PP++ P G P +PPPG GV P + Sbjct: 230 PGPGPGPGPGPG-----------PGPAPPNYSRPHGMGGPNMPPPG--PSGVPPGMPGQP 276 Query: 1465 PGGS----PYGQQVGVLGPPG--QQAPPPYPGPHPA-GPPVIQQPTTPMFVAPPPKTQ 1515 PGG P G P Q+ PP P P+ PP + +P+ PP+TQ Sbjct: 277 PGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM---PPQTQ 331 Score = 40.0 bits (92), Expect = 0.018 Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 1396 YEGMMGGYPPGLPP-LQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ 1454 Y+ + G P LP LQ V G M MQ P PPP + PG P PG Sbjct: 187 YKMLARGQP--LPDHLQMAVQGKRPMPGMQQQMPTLPPPS-VSATGPG----PGPG---P 236 Query: 1455 GVAPMVGTPAPGGS-PYGQQVGVLGPPGQQ-APPPYPGPHPAGPP----------VIQQP 1502 G P G P S P+G + PPG PP PG P GPP Sbjct: 237 GPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPT 296 Query: 1503 TTPMFVAPPPKTQR 1516 +TP + PP T R Sbjct: 297 STPQKLIPPQPTGR 310 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 89.7 bits (221), Expect = 2e-17 Identities = 50/171 (29%), Positives = 93/171 (54%), Gaps = 24/171 (14%) Query: 587 KEKRKELGPLPDDDDMASPKLKLSRKSG--ISPKKSKYMTPMQQKLNEVYEAVKNYTDK- 643 +++R+ + P +D+ K + R +SP K + +++N + + V NY D+ Sbjct: 1346 RKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPK----LTKQMNAIIDTVINYKDRC 1401 Query: 644 -----------------RGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKY 686 GR+LS +F++LPSR ELP+YY I+KP+D +KI+ + +KY Sbjct: 1402 NVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY 1461 Query: 687 QDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDS 737 + + + +D +++ +NA T+N S IY+D++VL V R+ + +E+S Sbjct: 1462 RSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEES 1512 Score = 88.6 bits (218), Expect = 4e-17 Identities = 51/147 (34%), Positives = 83/147 (56%), Gaps = 28/147 (19%) Query: 198 NPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 257 N SGR +SE+F +LPS+ + P+YY +I++P+D K I +RI+N Y+S+ + KD+ LL Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476 Query: 258 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMAL 317 NA+T+N GSQ+++D+ ++ +F + +I E ++ SN+ Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDE---SNE--------------- 1518 Query: 318 QYGSESEEDAALAAARYEEGESEAESI 344 E EED EE ESEA+S+ Sbjct: 1519 ---EEEEEDE-------EESESEAKSV 1535 Score = 86.3 bits (212), Expect = 2e-16 Identities = 44/159 (27%), Positives = 91/159 (57%), Gaps = 6/159 (3%) Query: 366 NNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFE 425 N+ G+ ++E F LPS+K+ P+YY+ I+ P+ ++I+ +++N +Y +L LE D+ L+ Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476 Query: 426 NAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKN 485 NA+ +N+ S IY+ + LQ V ++ ++++A+ ++ ED S + + +S+ Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED-----ESNEEEEEEDEEESESE 1531 Query: 486 IRKQRMKILFNVVLE-AREPGSGRRLCDLFMVKPSKKDY 523 + ++KI N + R+ G G++ + KP D+ Sbjct: 1532 AKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDF 1570 Score = 85.1 bits (209), Expect = 5e-16 Identities = 40/110 (36%), Positives = 69/110 (62%) Query: 492 KILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGE 551 K+ N LE SGR+L ++F+ PS+K+ P+YY++I +P+D K I+ IRN KY Sbjct: 1405 KVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSL 1464 Query: 552 EGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDD 601 + +D+ L+ NA+ +N EGSQ+Y D+ +L+ + K R+++ + +D Sbjct: 1465 GDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESED 1514 Score = 72.8 bits (177), Expect = 3e-12 Identities = 31/109 (28%), Positives = 67/109 (61%) Query: 62 DEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFN 121 + GR L E+FI+ P R+ P+YYE++ +P+D KI+++++ +Y + L D LL + Sbjct: 1417 NSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCH 1476 Query: 122 NAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQ 170 NA+++ S Y+ + L ++ R + ++ E++DE ++E+ ++++ Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDE 1525 Score = 47.8 bits (112), Expect = 9e-05 Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 9/120 (7%) Query: 785 KPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIR 844 + P+ F I++ + N++YR L ++ + + A+ N S+IYED++ LQ F R Sbjct: 1444 RKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSAR 1503 Query: 845 DELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSG 904 ++ K E + + + E+E +E+ E + K+K + K++ + + G Sbjct: 1504 QKIAKEEE---------SEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKG 1554 Score = 40.4 bits (93), Expect = 0.014 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 10/118 (8%) Query: 1406 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQ-GVAPMVGTPA 1464 G+ + P+DG+ G ++ +H G + P PG+ PP M+Q M P+ Sbjct: 69 GMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMG--PPQSPMDQHSQGYMSPHPS 126 Query: 1465 PGGSP--YGQQVGVLGPPGQQAPPPYPGP-HPAGPPVIQQPTTPMFVAPPPKTQRLLH 1519 P G+P + GP Q PP PG P P + QP P P + LH Sbjct: 127 PLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNR----GPSPFSPVQLH 180 Score = 35.8 bits (81), Expect = 0.34 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 1444 PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP-PPYPGPHPAGP-PVIQQ 1501 P P P + + PAPGG P PP P P P P P P PV+Q Sbjct: 262 PSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAAAVPGPSVPQPAPGQPSPVLQL 321 Query: 1502 PTTPMFVAPPPKTQRL 1517 ++P K Q L Sbjct: 322 QQKQSRISPIQKPQGL 337 Score = 32.7 bits (73), Expect = 2.9 Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 20/72 (27%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHP---------------GGPPPHHLPPGVPG--LPGIP 1447 PG+ P Q P+D S G M P HP GGP P +PP PG +PG P Sbjct: 104 PGMGPPQSPMDQH-SQGYMSP-HPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDP 161 Query: 1448 PP-GVMNQGVAP 1458 N+G +P Sbjct: 162 QAMSQPNRGPSP 173 >gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] Length = 2964 Score = 85.5 bits (210), Expect = 4e-16 Identities = 67/262 (25%), Positives = 110/262 (41%), Gaps = 33/262 (12%) Query: 1110 EPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPR--------------------VGRIEK 1149 +PGC YF L +D+ L+ GDCV++ P + RIEK Sbjct: 2642 QPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEK 2701 Query: 1150 VWVRDGAAYF-YGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKD 1208 +W + F +G + P ET H P++ FY E+F L E P+ ++G C VL Sbjct: 2702 LWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYT 2761 Query: 1209 FLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKE 1268 + RP + E D+ +C+ R DK F + R +F K + P+K+ Sbjct: 2762 YCKGRPKGVKEQDVYICDYRL---DKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKD 2818 Query: 1269 PSP--LLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPY 1326 SP + + + + E ++++G+ED +LP ++ LAS+ Sbjct: 2819 FSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDD------ALPLIEEVLASQEQAANE 2872 Query: 1327 TPPQSTPKSAKGSAK-KEGSKR 1347 P P+ +A EG K+ Sbjct: 2873 IPSLEEPEREGATANVSEGEKK 2894 Score = 73.6 bits (179), Expect = 1e-12 Identities = 31/101 (30%), Positives = 58/101 (57%) Query: 948 IERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMF 1007 IE+LW++ E++ +G ++RP+ET H +R+F E+F+ Y +P+ ++G C V+ Sbjct: 2699 IEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLD 2758 Query: 1008 VKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI 1048 + Y K P+ +++DV++C+ R F KI P+ Sbjct: 2759 LYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPV 2799 Score = 64.7 bits (156), Expect = 7e-10 Identities = 32/99 (32%), Positives = 50/99 (50%) Query: 52 ELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNL 111 E+ + I YKD + L + P ++ DYYE +S P+DL+ I++++ Y V Sbjct: 2446 EICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEA 2505 Query: 112 LTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNE 150 AD +F NA+ YY SP + C+L Y R+E Sbjct: 2506 FDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544 Score = 63.9 bits (154), Expect = 1e-09 Identities = 33/129 (25%), Positives = 72/129 (55%) Query: 354 FYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETL 413 F ++ D + S +++ Q +A P +LP KKK DYY++I P+ L I ++ Y+T+ Sbjct: 2444 FKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTV 2503 Query: 414 DHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATS 473 + + D+ +F NA++Y S + + V +L++ + E + + D G++ + +S Sbjct: 2504 EAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSS 2563 Query: 474 DTGSAKRKS 482 +T +++++ Sbjct: 2564 ETSVSEKEN 2572 Score = 58.5 bits (140), Expect = 5e-08 Identities = 33/112 (29%), Positives = 60/112 (53%) Query: 175 EGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIA 234 E + A L +I +++ + I+ + S + ++ LP K + DYY I +P+DL TI Sbjct: 2433 EVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIE 2492 Query: 235 QRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAE 286 ++I G YK++ A D+ + +NA+ Y S V +D ++K +Y + E Sbjct: 2493 KQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHE 2544 Score = 53.9 bits (128), Expect = 1e-06 Identities = 29/114 (25%), Positives = 52/114 (45%) Query: 626 MQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANK 685 + Q E+ + + +Y D + L+A L LP + + DYY I P+D+ I ++ Sbjct: 2440 LAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGY 2499 Query: 686 YQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHV 739 Y+ +++ D + +F NA Y +S + +D L K R + D V Sbjct: 2500 YKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIV 2553 Score = 45.4 bits (106), Expect = 4e-04 Identities = 30/82 (36%), Positives = 35/82 (42%) Query: 518 PSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYN 577 P KK DYY+ I +P+DL IE I Y E DM +FRNA Y S V Sbjct: 2470 PPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGR 2529 Query: 578 DAHILEKLLKEKRKELGPLPDD 599 D L K R E D+ Sbjct: 2530 DVCRLRKAYYNARHEASAQIDE 2551 >gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] Length = 1872 Score = 84.0 bits (206), Expect = 1e-15 Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%) Query: 514 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 573 F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN Sbjct: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464 Query: 574 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 618 + + + L EK KE + PL DDDD + L ++K P Sbjct: 1465 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1524 Query: 619 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 678 + P+ +K +PDYY I PMD+E IR Sbjct: 1525 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1554 Query: 679 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 727 ++ +KYQ +S ++D ++ N+ YN PES K A + V +T Sbjct: 1555 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1603 Score = 77.0 bits (188), Expect = 1e-13 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%) Query: 351 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 409 ++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ + Sbjct: 1379 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1438 Query: 410 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 460 Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR + Sbjct: 1439 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1498 Query: 461 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 520 ++D D + S D NI Q+M + P S F +K Sbjct: 1499 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1534 Query: 521 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 574 K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ Sbjct: 1535 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588 Score = 70.9 bits (172), Expect = 1e-11 Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%) Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85 ++ P S RRR + T+ ++ + N +RD + F + DYY Sbjct: 1367 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1418 Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145 +++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL Sbjct: 1419 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1478 Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205 E ED + + + IL+ ++ ++A S Sbjct: 1479 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1527 Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265 F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P Sbjct: 1528 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1585 Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290 SQ K A I + Y E + H Sbjct: 1586 ESQYTKTAQEIVNVCYQTLTEYDEH 1610 Score = 53.1 bits (126), Expect = 2e-06 Identities = 25/73 (34%), Positives = 41/73 (56%) Query: 375 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 434 PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P Sbjct: 1527 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1586 Query: 435 SAIYKRVLKLQQV 447 S K ++ V Sbjct: 1587 SQYTKTAQEIVNV 1599 >gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] Length = 1893 Score = 84.0 bits (206), Expect = 1e-15 Identities = 63/229 (27%), Positives = 95/229 (41%), Gaps = 45/229 (19%) Query: 514 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 573 F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN Sbjct: 1426 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1485 Query: 574 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 618 + + + L EK KE + PL DDDD + L ++K P Sbjct: 1486 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1545 Query: 619 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 678 + P+ +K +PDYY I PMD+E IR Sbjct: 1546 SWPFHHPVNKKF------------------------------VPDYYKVIVNPMDLETIR 1575 Query: 679 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 727 ++ +KYQ +S ++D ++ N+ YN PES K A + V +T Sbjct: 1576 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQT 1624 Score = 77.0 bits (188), Expect = 1e-13 Identities = 66/234 (28%), Positives = 106/234 (45%), Gaps = 34/234 (14%) Query: 351 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 409 ++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ + Sbjct: 1400 TDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRL 1459 Query: 410 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 460 Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR + Sbjct: 1460 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1519 Query: 461 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 520 ++D D + S D NI Q+M + P S F +K Sbjct: 1520 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1555 Query: 521 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 574 K PDYYK+I+ PMDL+ I NI KY E ++D+ L+ N+ YN SQ Sbjct: 1556 KFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1609 Score = 70.9 bits (172), Expect = 1e-11 Identities = 59/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%) Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85 ++ P S RRR + T+ ++ + N +RD + F + DYY Sbjct: 1388 LNRPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTYP------FHTPVNAKVVKDYY 1439 Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145 +++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL Sbjct: 1440 KIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1499 Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205 E ED + + + IL+ ++ ++A S Sbjct: 1500 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1548 Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265 F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P Sbjct: 1549 --FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1606 Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290 SQ K A I + Y E + H Sbjct: 1607 ESQYTKTAQEIVNVCYQTLTEYDEH 1631 Score = 53.1 bits (126), Expect = 2e-06 Identities = 25/73 (34%), Positives = 41/73 (56%) Query: 375 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 434 PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P Sbjct: 1548 PFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1607 Query: 435 SAIYKRVLKLQQV 447 S K ++ V Sbjct: 1608 SQYTKTAQEIVNV 1620 >gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sapiens] Length = 1826 Score = 81.3 bits (199), Expect = 7e-15 Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 45/229 (19%) Query: 514 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 573 F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN Sbjct: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483 Query: 574 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 618 + + + L EK KE + PL DDDD + L ++K P Sbjct: 1484 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1543 Query: 619 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 678 + P+ +K +PDYY I P+D+E IR Sbjct: 1544 SWPFHHPVNKKF------------------------------VPDYYKMIVNPVDLETIR 1573 Query: 679 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 727 ++ +KYQ +S ++D ++ N+ YN PES K A + + +T Sbjct: 1574 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQT 1622 Score = 73.6 bits (179), Expect = 1e-12 Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 34/234 (14%) Query: 351 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 409 ++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++ Sbjct: 1398 TDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCL 1457 Query: 410 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 460 Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR + Sbjct: 1458 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1517 Query: 461 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 520 ++D D + S D NI Q+M + P S F +K Sbjct: 1518 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1553 Query: 521 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 574 K PDYYK+I+ P+DL+ I NI KY E ++D+ L+ N+ YN SQ Sbjct: 1554 KFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607 Score = 69.7 bits (169), Expect = 2e-11 Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%) Query: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85 ++ P S RRR + T+ ++ + N +RD + F + DYY Sbjct: 1386 LNIPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTHP------FHTPVNAKVVKDYY 1437 Query: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145 +++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL Sbjct: 1438 KIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1497 Query: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205 E ED + + + IL+ ++ ++A S Sbjct: 1498 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1546 Query: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265 F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P Sbjct: 1547 --FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1604 Query: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290 SQ K A I I Y E + H Sbjct: 1605 ESQYTKTAQEIVNICYQTITEYDEH 1629 Score = 54.3 bits (129), Expect = 9e-07 Identities = 24/73 (32%), Positives = 41/73 (56%) Query: 375 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 434 PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P Sbjct: 1546 PFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1605 Query: 435 SAIYKRVLKLQQV 447 S K ++ + Sbjct: 1606 SQYTKTAQEIVNI 1618 >gi|16445438 bromodomain and WD repeat domain containing 1 isoform B [Homo sapiens] Length = 2269 Score = 74.7 bits (182), Expect = 7e-13 Identities = 59/232 (25%), Positives = 101/232 (43%), Gaps = 30/232 (12%) Query: 385 YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYK----- 439 YP Y + P L IR +L N+ Y L L ++ + NA+ +N P S I + Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253 Query: 440 -----RVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK---SKKNIR---- 487 + +K Q + +D ++ + + S T S +R+ KK+IR Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313 Query: 488 -----KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHN 542 K++ K L N++ + + R+ DL +YPDY II PMD + Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLV-------EYPDYRDIIDTPMDFGTVRET 1366 Query: 543 IRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEKLLKEKRKEL 593 + Y +D++L+F NA+ Y + S++Y+ L L +EK K++ Sbjct: 1367 LDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418 Score = 73.9 bits (180), Expect = 1e-12 Identities = 71/301 (23%), Positives = 127/301 (42%), Gaps = 40/301 (13%) Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276 YP Y ++ P DL TI R+ N Y+ + A+ ++ + NA+T+NEP S + A S Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVI---ARSA 1250 Query: 277 KKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAA---- 332 KKI ++ K + N+ LS + + +E +D+ L Sbjct: 1251 KKIT---------DQLLKF---IKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGR 1298 Query: 333 -RYEEGESEAESITSFMDVS--NPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYY 389 R +G+ + T++++ + +L + + C ++ EPF +YPDY Sbjct: 1299 RRVHDGKKSIRA-TNYVESNWKKQCKELVNLIFQCEDS------EPFRQPVDLVEYPDYR 1351 Query: 390 QQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN--SAIYKRVLKLQQV 447 I P+ +R L Y++ D+ L+F NAK Y PN S IY L+L + Sbjct: 1352 DIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY-TPNKRSKIYSMTLRLSAL 1410 Query: 448 MQAKKKELAR--------RDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVL 499 + K K+++ + + S KS +N++ +R+K ++ Sbjct: 1411 FEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIP 1470 Query: 500 E 500 E Sbjct: 1471 E 1471 Score = 65.1 bits (157), Expect = 5e-10 Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 30/230 (13%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 P Y VV+ P DL I+ +L Y ++ L + + + +NA+++ +P+S ++A K+ Sbjct: 1195 PKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKIT 1254 Query: 142 DLYLR-------TRNEFVQKGEADDEDDDEDGQDNQGTVTEGSS---------------- 178 D L+ T + +DE + ED D+ T Sbjct: 1255 DQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYV 1314 Query: 179 PAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQ 238 + K+ ++L+ I + SE F++ V+YPDY II P+D T+ + + Sbjct: 1315 ESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLD 1368 Query: 239 NGSYKSIHAMAKDIDLLAKNAKTYN-EPGSQVFKDANSIKKIFYMKKAEI 287 G+Y S KDI L+ NAK Y S+++ + +F K +I Sbjct: 1369 AGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418 Score = 51.2 bits (121), Expect = 8e-06 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 28/234 (11%) Query: 523 YPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAH-I 581 YP Y ++ P DL I + N Y ++ +++ + NAR +NE S + A I Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253 Query: 582 LEKLLK---------------EKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPM 626 ++LLK + D DD PK R+ KKS T Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313 Query: 627 -----QQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHM 681 +++ E+ + D S F + E PDY I PMD +R + Sbjct: 1314 VESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETL 1367 Query: 682 MANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVLHKVLLETRRDLEGD 734 A Y +D ++F+NA Y S IY L L + E + + D Sbjct: 1368 DAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSD 1421 Score = 41.6 bits (96), Expect = 0.006 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 17/142 (11%) Query: 18 DFDDGHHSVSTPGPSR-----KRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELF 72 D DD ++ G R K R +N + C EL N I +D E F Sbjct: 1285 DLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDS------EPF 1338 Query: 73 IRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSP 132 + PDY +++ P+D +++ L YD D +L+F+NAK+Y +P Sbjct: 1339 RQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY----TP 1394 Query: 133 EYKAACKLWDLYLRTRNEFVQK 154 ++ K++ + LR F +K Sbjct: 1395 NKRS--KIYSMTLRLSALFEEK 1414 >gi|16445436 bromodomain and WD repeat domain containing 1 isoform A [Homo sapiens] Length = 2320 Score = 74.7 bits (182), Expect = 7e-13 Identities = 59/232 (25%), Positives = 101/232 (43%), Gaps = 30/232 (12%) Query: 385 YPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYK----- 439 YP Y + P L IR +L N+ Y L L ++ + NA+ +N P S I + Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253 Query: 440 -----RVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRK---SKKNIR---- 487 + +K Q + +D ++ + + S T S +R+ KK+IR Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313 Query: 488 -----KQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHN 542 K++ K L N++ + + R+ DL +YPDY II PMD + Sbjct: 1314 VESNWKKQCKELVNLIFQCEDSEPFRQPVDLV-------EYPDYRDIIDTPMDFGTVRET 1366 Query: 543 IRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEKLLKEKRKEL 593 + Y +D++L+F NA+ Y + S++Y+ L L +EK K++ Sbjct: 1367 LDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418 Score = 73.9 bits (180), Expect = 1e-12 Identities = 71/301 (23%), Positives = 127/301 (42%), Gaps = 40/301 (13%) Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276 YP Y ++ P DL TI R+ N Y+ + A+ ++ + NA+T+NEP S + A S Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVI---ARSA 1250 Query: 277 KKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAA---- 332 KKI ++ K + N+ LS + + +E +D+ L Sbjct: 1251 KKIT---------DQLLKF---IKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGR 1298 Query: 333 -RYEEGESEAESITSFMDVS--NPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYY 389 R +G+ + T++++ + +L + + C ++ EPF +YPDY Sbjct: 1299 RRVHDGKKSIRA-TNYVESNWKKQCKELVNLIFQCEDS------EPFRQPVDLVEYPDYR 1351 Query: 390 QQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN--SAIYKRVLKLQQV 447 I P+ +R L Y++ D+ L+F NAK Y PN S IY L+L + Sbjct: 1352 DIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY-TPNKRSKIYSMTLRLSAL 1410 Query: 448 MQAKKKELAR--------RDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVL 499 + K K+++ + + S KS +N++ +R+K ++ Sbjct: 1411 FEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIP 1470 Query: 500 E 500 E Sbjct: 1471 E 1471 Score = 65.1 bits (157), Expect = 5e-10 Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 30/230 (13%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 P Y VV+ P DL I+ +L Y ++ L + + + +NA+++ +P+S ++A K+ Sbjct: 1195 PKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKIT 1254 Query: 142 DLYLR-------TRNEFVQKGEADDEDDDEDGQDNQGTVTEGSS---------------- 178 D L+ T + +DE + ED D+ T Sbjct: 1255 DQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYV 1314 Query: 179 PAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQ 238 + K+ ++L+ I + SE F++ V+YPDY II P+D T+ + + Sbjct: 1315 ESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLD 1368 Query: 239 NGSYKSIHAMAKDIDLLAKNAKTYN-EPGSQVFKDANSIKKIFYMKKAEI 287 G+Y S KDI L+ NAK Y S+++ + +F K +I Sbjct: 1369 AGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKI 1418 Score = 51.2 bits (121), Expect = 8e-06 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 28/234 (11%) Query: 523 YPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAH-I 581 YP Y ++ P DL I + N Y ++ +++ + NAR +NE S + A I Sbjct: 1194 YPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKI 1253 Query: 582 LEKLLK---------------EKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPM 626 ++LLK + D DD PK R+ KKS T Sbjct: 1254 TDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNY 1313 Query: 627 -----QQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHM 681 +++ E+ + D S F + E PDY I PMD +R + Sbjct: 1314 VESNWKKQCKELVNLIFQCED------SEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETL 1367 Query: 682 MANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVLHKVLLETRRDLEGD 734 A Y +D ++F+NA Y S IY L L + E + + D Sbjct: 1368 DAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSD 1421 Score = 41.6 bits (96), Expect = 0.006 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 17/142 (11%) Query: 18 DFDDGHHSVSTPGPSR-----KRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELF 72 D DD ++ G R K R +N + C EL N I +D E F Sbjct: 1285 DLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDS------EPF 1338 Query: 73 IRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSP 132 + PDY +++ P+D +++ L YD D +L+F+NAK+Y +P Sbjct: 1339 RQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAY----TP 1394 Query: 133 EYKAACKLWDLYLRTRNEFVQK 154 ++ K++ + LR F +K Sbjct: 1395 NKRS--KIYSMTLRLSALFEEK 1414 >gi|34996489 pleckstrin homology domain interacting protein [Homo sapiens] Length = 1821 Score = 73.9 bits (180), Expect = 1e-12 Identities = 60/223 (26%), Positives = 103/223 (46%), Gaps = 35/223 (15%) Query: 68 LCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYY 127 + F+ + P Y VV+ P DL I+Q+L+ Y V+ L + + + +N +++ Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239 Query: 128 KPDSPEYKAACKLWDLYLR------------TRNEFVQKGEADDEDDDEDGQDNQGTVTE 175 +P SP K+A + DL L N +K +D ED+++D D GT T Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDA-DVPGTSTR 1298 Query: 176 ------------GSSPAY----LKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPD 219 + +Y K+ E+LL I + SE F++ ++YPD Sbjct: 1299 KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCED------SEPFRQPVDLLEYPD 1352 Query: 220 YYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTY 262 Y II P+D T+ + ++ G+Y+S + KD+ L+ N+K Y Sbjct: 1353 YRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAY 1395 Score = 73.9 bits (180), Expect = 1e-12 Identities = 71/279 (25%), Positives = 118/279 (42%), Gaps = 31/279 (11%) Query: 217 YPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSI 276 YP Y ++ P DL TI QR++N Y+ + ++ ++ + N +T+NEPGS + K A + Sbjct: 1193 YPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFV 1252 Query: 277 KK-IFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYE 335 + + K + ++ + L S K+ V A G+ + + R Sbjct: 1253 TDLLLHFIKDQTCYNII---PLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRL 1309 Query: 336 EGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMP 395 +++ I ++ +L + + C + +EPF +YPDY I P Sbjct: 1310 RNRAQSYDIQAW---KKQCEELLNLIFQCED------SEPFRQPVDLLEYPDYRDIIDTP 1360 Query: 396 ISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYN-VPNSAIYKRVLKLQQVMQAKKKE 454 + +R L+ YE+ L D+ L+F N+K Y S IY L+L Sbjct: 1361 MDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFF------ 1414 Query: 455 LARRDDIEDGDSMISSATSDTGSAKRKSKKN-IRKQRMK 492 + ISS SD SA R K+N I K+R K Sbjct: 1415 ----------EEHISSVLSDYKSALRFHKRNTITKRRKK 1443 Score = 61.2 bits (147), Expect = 8e-09 Identities = 55/244 (22%), Positives = 99/244 (40%), Gaps = 34/244 (13%) Query: 372 IAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYN 431 IA F + YP Y + P L I+ +L+N+ Y + L ++ + N + +N Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239 Query: 432 VPNSAIYKRVLKLQQVM-----------------QAKKKELARRDDIE-DGDSMISSATS 473 P S I K + ++ KKK L+ +D E D D +S Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRK 1299 Query: 474 DTGSAKRKSKKN--------IRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD 525 R+ +N K++ + L N++ + + R+ DL +YPD Sbjct: 1300 RKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLL-------EYPD 1352 Query: 526 YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYN-EEGSQVYNDAHILEK 584 Y II PMD + + Y + +D++L+F N++ Y + S++Y+ + L Sbjct: 1353 YRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSA 1412 Query: 585 LLKE 588 +E Sbjct: 1413 FFEE 1416 Score = 54.7 bits (130), Expect = 7e-07 Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 20/231 (8%) Query: 510 LCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYN 569 + F+ + YP Y ++ P DL I+ + N Y ++ +++ + N R +N Sbjct: 1180 IASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFN 1239 Query: 570 EEGSQVYNDAHILEKLLKEKRKE---LGPLPDDDDMASPKLKLSRKS-------GISPKK 619 E GS + A + LL K+ +P + M L S G S +K Sbjct: 1240 EPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRK 1299 Query: 620 SKYMTPMQQKLNEVYE-AVKNYTDKRGRRLSAIF-------LRLP-SRSELPDYYLTIKK 670 K P ++ N ++ + + L+ IF R P E PDY I Sbjct: 1300 RKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDT 1359 Query: 671 PMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYN-EPESLIYKDALVL 720 PMD +R + A Y+ + +D ++F+N+ Y S IY +L L Sbjct: 1360 PMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRL 1410 Score = 34.7 bits (78), Expect = 0.76 Identities = 19/69 (27%), Positives = 34/69 (49%) Query: 662 PDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLH 721 P Y + P D+ I+ + Y+ + S++ + + +N T+NEP S I K A + Sbjct: 1194 PMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVT 1253 Query: 722 KVLLETRRD 730 +LL +D Sbjct: 1254 DLLLHFIKD 1262 Score = 31.2 bits (69), Expect = 8.4 Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 5/117 (4%) Query: 787 PLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIK-IRD 845 P I++ +EN YRR+ + + R N S I + A + + I+D Sbjct: 1203 PTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKD 1262 Query: 846 ELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDS 902 + C N + P + K + +D E E K+ K K + +R S Sbjct: 1263 QTCYN----IIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQS 1315 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 66.6 bits (161), Expect = 2e-10 Identities = 47/122 (38%), Positives = 55/122 (45%), Gaps = 28/122 (22%) Query: 1397 EGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV 1456 +G+ G PPG+P + GP P GPP P G PGLPG PPG G Sbjct: 491 QGLQG--PPGIPGIGGPSG------------PIGPPGIPGPKGEPGLPG--PPGFPGIGK 534 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPKTQ 1515 + G P G P G LGP GQ P PG P P GPP + PT PPP+ + Sbjct: 535 PGVAGLHGPPGKP-----GALGPQGQPGLPGPPGPPGPPGPPAVMPPT------PPPQGE 583 Query: 1516 RL 1517 L Sbjct: 584 YL 585 Score = 57.4 bits (137), Expect = 1e-07 Identities = 39/90 (43%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPG--GPPPHHLPPGVPGLPGIPPPGVMN-QGVAPMV 1460 P GLP QG G P PG GPP H PPG GLPG+ PGV G + Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL 286 Query: 1461 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1490 G P G P Q G +G PG Q PP PG Sbjct: 287 GKPGAPGEPGPQ--GPIGVPGVQGPPGIPG 314 Score = 51.6 bits (122), Expect = 6e-06 Identities = 48/148 (32%), Positives = 60/148 (40%), Gaps = 40/148 (27%) Query: 1400 MGGYP--PGLPPLQGPVDGLVSMGSMQP------LHPGGPPPHHLPPGVPGLPGIP---- 1447 +GG P PGLP + GP+ ++G P + P GPP PG+ G PG P Sbjct: 385 IGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLG 444 Query: 1448 ---PPGVMN-------QGVAPMVGTPAPGGSPYGQQVGVLGPPGQ---------QAPPPY 1488 PPG+ +G A G P G P G+LGP G+ Q PP Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP-----GLLGPKGEPGIPGDQGLQGPPGI 499 Query: 1489 PG----PHPAGPPVIQQPTTPMFVAPPP 1512 PG P GPP I P + PP Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Score = 51.2 bits (121), Expect = 8e-06 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 3/111 (2%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P G V G P+ P G PG+PG+PG+ P G+ G Sbjct: 437 PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP-KGEPGIPGDQGLQG 495 Query: 1465 PGGSP-YGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPK 1513 P G P G G +GPPG P PG P P G P I +P PP K Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGK 546 Score = 48.1 bits (113), Expect = 7e-05 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMN-------QGVA 1457 PG P G +G + P G P PPG GLPGI PG +G Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 225 Query: 1458 PMVGTPAPGG--SPYGQQ-VGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAP 1510 G P P G P G + G+ G PG + PP G P P G P + +P F P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGP 282 Score = 48.1 bits (113), Expect = 7e-05 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 21/100 (21%) Query: 1404 PPGLPPL-------------QGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPG 1450 PPGLP + G V G ++G P G P PPG PGLPGIP P Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPG--ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP- 400 Query: 1451 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1490 G +G P P G G VG GPPG + P G Sbjct: 401 ---MGPPGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQG 435 Score = 47.0 bits (110), Expect = 1e-04 Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 15/109 (13%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP-------PPGVMNQGV 1456 PPG+ GPV GL +G +P G P P P G PG PG P PGV Sbjct: 256 PPGMHGPPGPV-GLPGVG--KPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPG 311 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTP 1505 P +G P G P Q G G G+Q P PG P G P I +P P Sbjct: 312 IPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLPG--PPGLPGIGKPGFP 356 Score = 46.6 bits (109), Expect = 2e-04 Identities = 43/123 (34%), Positives = 50/123 (40%), Gaps = 26/123 (21%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPG-----GPPPHHLPPGVPGLPGI------------ 1446 P G+P QGP G +P PG GP P G+PG G+ Sbjct: 189 PMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248 Query: 1447 PPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP------PPYPGPH-PAGPPVI 1499 PGV +G M G P P G P + GV G PG Q P P PGP P G P + Sbjct: 249 GAPGV--KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGV 306 Query: 1500 QQP 1502 Q P Sbjct: 307 QGP 309 Score = 46.2 bits (108), Expect = 3e-04 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 43/131 (32%) Query: 1406 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVP-----------------------G 1442 G P QGP+ + G P P G P PPG+P G Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337 Query: 1443 LPGIP-PPGVMNQGVAPMVGTPAPGG-----------SPYGQQVGVLGPPGQQAPPPYPG 1490 LPG+P PPG+ G G P P G P G++ G +G PG PP PG Sbjct: 338 LPGLPGPPGLPGIG---KPGFPGPKGDRGMGGVPGALGPRGEK-GPIGAPGIGGPPGEPG 393 Query: 1491 ----PHPAGPP 1497 P P GPP Sbjct: 394 LPGIPGPMGPP 404 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 22/107 (20%) Query: 1430 GPPPHHLPPGVPGLPGIPP---------------PGVMNQGVAPMVGTPAPGGSPYGQ-- 1472 GP P G PG PG+P PGV G+ M G P G P + Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180 Query: 1473 --QVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPP-PKTQR 1516 Q G +GP G P PGPH G P I +P P P PK R Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPH--GLPGIGKPGGPGLPGQPGPKGDR 225 Score = 39.3 bits (90), Expect = 0.031 Identities = 45/128 (35%), Positives = 53/128 (41%), Gaps = 14/128 (10%) Query: 1404 PPGLPPLQGPVDGLVSMGS--MQPLH-PGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1460 P G P L GP G +G + LH P G P P G PGLPG P P A M Sbjct: 517 PKGEPGLPGP-PGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575 Query: 1461 GTPAPGGSPYGQQVGVLGPPGQQAPPPY-------PGPHPAGPPVIQQPTTPM-FVAPPP 1512 TP P G Y +G LG G + P Y GP P + T P V P Sbjct: 576 PTPPPQGE-YLPDMG-LGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPV 633 Query: 1513 KTQRLLHS 1520 K +LL++ Sbjct: 634 KFNKLLYN 641 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 66.6 bits (161), Expect = 2e-10 Identities = 47/122 (38%), Positives = 55/122 (45%), Gaps = 28/122 (22%) Query: 1397 EGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV 1456 +G+ G PPG+P + GP P GPP P G PGLPG PPG G Sbjct: 491 QGLQG--PPGIPGIGGPSG------------PIGPPGIPGPKGEPGLPG--PPGFPGIGK 534 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPKTQ 1515 + G P G P G LGP GQ P PG P P GPP + PT PPP+ + Sbjct: 535 PGVAGLHGPPGKP-----GALGPQGQPGLPGPPGPPGPPGPPAVMPPT------PPPQGE 583 Query: 1516 RL 1517 L Sbjct: 584 YL 585 Score = 57.4 bits (137), Expect = 1e-07 Identities = 39/90 (43%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPG--GPPPHHLPPGVPGLPGIPPPGVMN-QGVAPMV 1460 P GLP QG G P PG GPP H PPG GLPG+ PGV G + Sbjct: 227 PKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPL 286 Query: 1461 GTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1490 G P G P Q G +G PG Q PP PG Sbjct: 287 GKPGAPGEPGPQ--GPIGVPGVQGPPGIPG 314 Score = 51.6 bits (122), Expect = 6e-06 Identities = 48/148 (32%), Positives = 60/148 (40%), Gaps = 40/148 (27%) Query: 1400 MGGYP--PGLPPLQGPVDGLVSMGSMQP------LHPGGPPPHHLPPGVPGLPGIP---- 1447 +GG P PGLP + GP+ ++G P + P GPP PG+ G PG P Sbjct: 385 IGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLG 444 Query: 1448 ---PPGVMN-------QGVAPMVGTPAPGGSPYGQQVGVLGPPGQ---------QAPPPY 1488 PPG+ +G A G P G P G+LGP G+ Q PP Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVP-----GLLGPKGEPGIPGDQGLQGPPGI 499 Query: 1489 PG----PHPAGPPVIQQPTTPMFVAPPP 1512 PG P GPP I P + PP Sbjct: 500 PGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Score = 51.2 bits (121), Expect = 8e-06 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 3/111 (2%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P G V G P+ P G PG+PG+PG+ P G+ G Sbjct: 437 PGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGP-KGEPGIPGDQGLQG 495 Query: 1465 PGGSP-YGQQVGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAPPPK 1513 P G P G G +GPPG P PG P P G P I +P PP K Sbjct: 496 PPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGK 546 Score = 48.1 bits (113), Expect = 7e-05 Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMN-------QGVA 1457 PG P G +G + P G P PPG GLPGI PG +G Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 225 Query: 1458 PMVGTPAPGG--SPYGQQ-VGVLGPPGQQAPPPYPG-PHPAGPPVIQQPTTPMFVAP 1510 G P P G P G + G+ G PG + PP G P P G P + +P F P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGP 282 Score = 48.1 bits (113), Expect = 7e-05 Identities = 37/100 (37%), Positives = 42/100 (42%), Gaps = 21/100 (21%) Query: 1404 PPGLPPL-------------QGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPG 1450 PPGLP + G V G ++G P G P PPG PGLPGIP P Sbjct: 344 PPGLPGIGKPGFPGPKGDRGMGGVPG--ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP- 400 Query: 1451 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPG 1490 G +G P P G G VG GPPG + P G Sbjct: 401 ---MGPPGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQG 435 Score = 47.0 bits (110), Expect = 1e-04 Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 15/109 (13%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIP-------PPGVMNQGV 1456 PPG+ GPV GL +G +P G P P P G PG PG P PGV Sbjct: 256 PPGMHGPPGPV-GLPGVG--KPGVTGFPGPQG-PLGKPGAPGEPGPQGPIGVPGVQGPPG 311 Query: 1457 APMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTP 1505 P +G P G P Q G G G+Q P PG P G P I +P P Sbjct: 312 IPGIGKPGQDGIP--GQPGFPGGKGEQGLPGLPG--PPGLPGIGKPGFP 356 Score = 46.6 bits (109), Expect = 2e-04 Identities = 43/123 (34%), Positives = 50/123 (40%), Gaps = 26/123 (21%) Query: 1404 PPGLPPLQGPVDGLVSMGSMQPLHPG-----GPPPHHLPPGVPGLPGI------------ 1446 P G+P QGP G +P PG GP P G+PG G+ Sbjct: 189 PMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248 Query: 1447 PPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAP------PPYPGPH-PAGPPVI 1499 PGV +G M G P P G P + GV G PG Q P P PGP P G P + Sbjct: 249 GAPGV--KGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGV 306 Query: 1500 QQP 1502 Q P Sbjct: 307 QGP 309 Score = 46.2 bits (108), Expect = 3e-04 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 43/131 (32%) Query: 1406 GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVP-----------------------G 1442 G P QGP+ + G P P G P PPG+P G Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQG 337 Query: 1443 LPGIP-PPGVMNQGVAPMVGTPAPGG-----------SPYGQQVGVLGPPGQQAPPPYPG 1490 LPG+P PPG+ G G P P G P G++ G +G PG PP PG Sbjct: 338 LPGLPGPPGLPGIG---KPGFPGPKGDRGMGGVPGALGPRGEK-GPIGAPGIGGPPGEPG 393 Query: 1491 ----PHPAGPP 1497 P P GPP Sbjct: 394 LPGIPGPMGPP 404 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 22/107 (20%) Query: 1430 GPPPHHLPPGVPGLPGIPP---------------PGVMNQGVAPMVGTPAPGGSPYGQ-- 1472 GP P G PG PG+P PGV G+ M G P G P + Sbjct: 121 GPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGE 180 Query: 1473 --QVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPP-PKTQR 1516 Q G +GP G P PGPH G P I +P P P PK R Sbjct: 181 IGQKGEIGPMGIPGPQGPPGPH--GLPGIGKPGGPGLPGQPGPKGDR 225 Score = 39.3 bits (90), Expect = 0.031 Identities = 45/128 (35%), Positives = 53/128 (41%), Gaps = 14/128 (10%) Query: 1404 PPGLPPLQGPVDGLVSMGS--MQPLH-PGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV 1460 P G P L GP G +G + LH P G P P G PGLPG P P A M Sbjct: 517 PKGEPGLPGP-PGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMP 575 Query: 1461 GTPAPGGSPYGQQVGVLGPPGQQAPPPY-------PGPHPAGPPVIQQPTTPM-FVAPPP 1512 TP P G Y +G LG G + P Y GP P + T P V P Sbjct: 576 PTPPPQGE-YLPDMG-LGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPV 633 Query: 1513 KTQRLLHS 1520 K +LL++ Sbjct: 634 KFNKLLYN 641 >gi|46399200 testis-specific bromodomain protein [Homo sapiens] Length = 947 Score = 63.9 bits (154), Expect = 1e-09 Identities = 28/78 (35%), Positives = 45/78 (57%) Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273 K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119 Query: 274 NSIKKIFYMKKAEIEHHE 291 +++K+F K +++ E Sbjct: 120 QALEKLFMQKLSQMPQEE 137 Score = 62.0 bits (149), Expect = 4e-09 Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%) Query: 382 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 441 K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119 Query: 442 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 501 L+++ K ++ + + + I K+ +++NI V A Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159 Query: 502 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 561 +E S +F + +P K + P L +++ N + + +K Sbjct: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212 Query: 562 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 621 R A S V + E P + +A P +K + + P + Sbjct: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259 Query: 622 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 674 ++ ++L E +K K+ + F + L +YY +K PMD+ Sbjct: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319 Query: 675 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 723 I+ M +Y+D D +MF N YN P+ + A +L V Sbjct: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/76 (34%), Positives = 38/76 (50%) Query: 660 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 719 +LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121 Query: 720 LHKVLLETRRDLEGDE 735 L K+ ++ + +E Sbjct: 122 LEKLFMQKLSQMPQEE 137 Score = 52.8 bits (125), Expect = 3e-06 Identities = 75/374 (20%), Positives = 132/374 (35%), Gaps = 73/374 (19%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123 Query: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQLLEAIVVAT 197 L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q Sbjct: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ--------- 174 Query: 198 NPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 257 Q++PS P+++ +Q S S A + K Sbjct: 175 -----------QEIPSVFPKTSI-----SPLNV------VQGASVNSSSQTAAQVTKGVK 212 Query: 258 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIE--HHEMAKSSLRMSNKRAVQGGRLSAITM 315 P + K ++ F K + M K+ L S + Q + + + Sbjct: 213 RKADTTTPATSAVKASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ---QYNVVKTVKV 269 Query: 316 ALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEP 375 Q SE + A ++ + PFY D +N ++ P Sbjct: 270 TEQLRHCSEILKEMLAKKH-------------FSYAWPFYNPVDVNALGLHNYYDVVKNP 316 Query: 376 FYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS 435 + L I+ K+ NQEY+ D+ LMF N +YN P+ Sbjct: 317 --------------------MDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDH 356 Query: 436 AIYKRVLKLQQVMQ 449 + LQ V + Sbjct: 357 EVVTMARMLQDVFE 370 Score = 50.1 bits (118), Expect = 2e-05 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278 +YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++ Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367 Query: 279 IF--YMKKAEIE 288 +F + K IE Sbjct: 368 VFETHFSKIPIE 379 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%) Query: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584 +YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+ Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367 Query: 585 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 644 + + ++ P+ + M +K + + + ++ + K Sbjct: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426 Query: 645 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 704 +L A+ +L S++P L KK ++ + + N ++ M E M Sbjct: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484 Query: 705 TYNEPE 710 N+P+ Sbjct: 485 KRNQPK 490 >gi|46399198 testis-specific bromodomain protein [Homo sapiens] Length = 947 Score = 63.9 bits (154), Expect = 1e-09 Identities = 28/78 (35%), Positives = 45/78 (57%) Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273 K+Q PDYY IIK P+DL TI +R++N Y +D + + N YN+PG + A Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119 Query: 274 NSIKKIFYMKKAEIEHHE 291 +++K+F K +++ E Sbjct: 120 QALEKLFMQKLSQMPQEE 137 Score = 62.0 bits (149), Expect = 4e-09 Identities = 75/349 (21%), Positives = 129/349 (36%), Gaps = 47/349 (13%) Query: 382 KKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRV 441 K + PDYY IK P+ L I+ +L+N+ Y D N MF N YN P I Sbjct: 60 KLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMA 119 Query: 442 LKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEA 501 L+++ K ++ + + + I K+ +++NI V A Sbjct: 120 QALEKLFMQKLSQMPQEEQVVGVKERI----------KKGTQQNI----------AVSSA 159 Query: 502 REPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLM 561 +E S +F + +P K + P L +++ N + + +K Sbjct: 160 KEKSSPSATEKVFKQQEIPSVFP---KTSISP--LNVVQGASVNSSSQTAAQVTKGVK-- 212 Query: 562 FRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSK 621 R A S V + E P + +A P +K + + P + Sbjct: 213 -RKADTTTPATSAV------------KASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ 259 Query: 622 YMTPMQ-----QKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELP--DYYLTIKKPMDM 674 ++ ++L E +K K+ + F + L +YY +K PMD+ Sbjct: 260 QYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDL 319 Query: 675 EKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV 723 I+ M +Y+D D +MF N YN P+ + A +L V Sbjct: 320 GTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/76 (34%), Positives = 38/76 (50%) Query: 660 ELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALV 719 +LPDYY IK PMD+ I+ + Y +EDF MF+N YN+P I A Sbjct: 62 QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQA 121 Query: 720 LHKVLLETRRDLEGDE 735 L K+ ++ + +E Sbjct: 122 LEKLFMQKLSQMPQEE 137 Score = 52.8 bits (125), Expect = 3e-06 Identities = 75/374 (20%), Positives = 132/374 (35%), Gaps = 73/374 (19%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 PDYY ++ P+DL I+++L+ + Y + DF +F+N Y KP A L Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123 Query: 142 DLYLRTRNEFVQKGE--ADDEDDDEDGQDN--QGTVTEGSSPAYLKEILEQLLEAIVVAT 197 L+++ ++ Q+ + E + Q N + E SSP+ +++ +Q Sbjct: 124 KLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKEKSSPSATEKVFKQ--------- 174 Query: 198 NPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAK 257 Q++PS P+++ +Q S S A + K Sbjct: 175 -----------QEIPSVFPKTSI-----SPLNV------VQGASVNSSSQTAAQVTKGVK 212 Query: 258 NAKTYNEPGSQVFKDANSIKKIFYMKKAEIE--HHEMAKSSLRMSNKRAVQGGRLSAITM 315 P + K ++ F K + M K+ L S + Q + + + Sbjct: 213 RKADTTTPATSAVKASSEFSPTFTEKSVALPPIKENMPKNVLPDSQQ---QYNVVKTVKV 269 Query: 316 ALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEP 375 Q SE + A ++ + PFY D +N ++ P Sbjct: 270 TEQLRHCSEILKEMLAKKH-------------FSYAWPFYNPVDVNALGLHNYYDVVKNP 316 Query: 376 FYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS 435 + L I+ K+ NQEY+ D+ LMF N +YN P+ Sbjct: 317 --------------------MDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDH 356 Query: 436 AIYKRVLKLQQVMQ 449 + LQ V + Sbjct: 357 EVVTMARMLQDVFE 370 Score = 50.1 bits (118), Expect = 2e-05 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278 +YY ++K P+DL TI +++ N YK + A D+ L+ N YN P +V A ++ Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367 Query: 279 IF--YMKKAEIE 288 +F + K IE Sbjct: 368 VFETHFSKIPIE 379 Score = 43.5 bits (101), Expect = 0.002 Identities = 37/186 (19%), Positives = 74/186 (39%), Gaps = 3/186 (1%) Query: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584 +YY ++ PMDL I+ + N +Y D++LMF N YN +V A +L+ Sbjct: 308 NYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQD 367 Query: 585 LLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKR 644 + + ++ P+ + M +K + + + ++ + K Sbjct: 368 VFETHFSKI-PIEPVESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKL 426 Query: 645 GRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNAC 704 +L A+ +L S++P L KK ++ + + N ++ M E M Sbjct: 427 QEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQ--MRLKEKS 484 Query: 705 TYNEPE 710 N+P+ Sbjct: 485 KRNQPK 490 >gi|164419758 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 62.8 bits (151), Expect = 3e-09 Identities = 93/429 (21%), Positives = 163/429 (37%), Gaps = 83/429 (19%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 PDY++++ QP+D+ I+++L+ Y + DF +F N Y KP A L Sbjct: 111 PDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLE 170 Query: 142 DLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSG 201 ++L QK + +++ E L+ I ++ G Sbjct: 171 KIFL-------QKVASMPQEEQE------------------------LVVTIPKNSHKKG 199 Query: 202 RLISELFQKLPSKVQYP-----DYYAIIKEPIDLKTIAQRIQNGSY------KSIHAMAK 250 ++ L + S Q P + A+ P ++ T I + S KS+H+ Sbjct: 200 AKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP 259 Query: 251 DIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRL 310 LLA A P +Q +K+ K+ A+ L Sbjct: 260 P--LLAVTAA----PPAQPLAKKKGVKR---------------KADTTTPTPTAI----L 294 Query: 311 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDV-----SNPFYQLYDTVRSCR 365 + + A GS + A L R E G D S+ +L + ++ C Sbjct: 295 APGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCN 354 Query: 366 NNQGQLIAE-------PFYHL--PSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHL 416 +L+++ PFY S DY+ IK P+ L ++ K++N++Y Sbjct: 355 GILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEF 414 Query: 417 ECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTG 476 D+ LMF N +YN P+ + KLQ V + + ++ + +E G +S+A G Sbjct: 415 AADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP-DEPLEPGPLPVSTA-MPPG 472 Query: 477 SAKRKSKKN 485 AK S+ + Sbjct: 473 LAKSSSESS 481 Score = 62.4 bits (150), Expect = 3e-09 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 1/166 (0%) Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278 DY+ IIK P+DL T+ ++++N Y+ A D+ L+ N YN P V A ++ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQD 444 Query: 279 IFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGE 338 +F + A++ + L +S + S+ + + + SES + +E E Sbjct: 445 VFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEE 504 Query: 339 SEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKK 384 E+ES S + ++ +L + +R+ L P P +K+ Sbjct: 505 EESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPI-SKPKRKR 549 Score = 58.5 bits (140), Expect = 5e-08 Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%) Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273 K+ PDY+ IIK+P+D+ TI +R++N Y + +D + + N YN+P + A Sbjct: 107 KLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMA 166 Query: 274 NSIKKIFYMKKAEI--EHHEMAKSSLRMSNKRAVQGGRLSAI 313 +++KIF K A + E E+ + + S+K+ G +L+A+ Sbjct: 167 QTLEKIFLQKVASMPQEEQELVVTIPKNSHKK---GAKLAAL 205 Score = 52.0 bits (123), Expect = 5e-06 Identities = 28/82 (34%), Positives = 40/82 (48%) Query: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 720 LPDY+ IK+PMDM I+ + N Y ++DF MF N YN+P I A L Sbjct: 110 LPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTL 169 Query: 721 HKVLLETRRDLEGDEDSHVPNV 742 K+ L+ + +E V + Sbjct: 170 EKIFLQKVASMPQEEQELVVTI 191 Score = 48.9 bits (115), Expect = 4e-05 Identities = 24/70 (34%), Positives = 36/70 (51%) Query: 520 KKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDA 579 K PDY+KII +PMD+ I+ + N+ Y ++D MF N YN+ + A Sbjct: 107 KLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMA 166 Query: 580 HILEKLLKEK 589 LEK+ +K Sbjct: 167 QTLEKIFLQK 176 Score = 45.8 bits (107), Expect = 3e-04 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584 DY+ II PMDL ++ + N Y + D++LMF N YN V A L+ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQD 444 Query: 585 L-------LKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNE 632 + + ++ E GPLP M K S +S S+ + +++ +E Sbjct: 445 VFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDE 499 Score = 40.8 bits (94), Expect = 0.011 Identities = 18/50 (36%), Positives = 26/50 (52%) Query: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPE 710 L DY+ IK PMD+ ++ M Y+D D +MF+N YN P+ Sbjct: 383 LHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPD 432 Score = 40.0 bits (92), Expect = 0.018 Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 9/125 (7%) Query: 785 KPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF---- 840 K P+ +++ +EN YR F + + + N D ++ A +LQ F Sbjct: 391 KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 450 Query: 841 IKIRDELCKNGEILLS----PALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREA 896 K+ DE + G + +S P L+ ++ ++ E + +E EED+ EEE+ E+ Sbjct: 451 AKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSE-ESSSESSSEEEEEEDEEDEEEEESES 509 Query: 897 EKSED 901 SE+ Sbjct: 510 SDSEE 514 >gi|4826806 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 62.8 bits (151), Expect = 3e-09 Identities = 93/429 (21%), Positives = 163/429 (37%), Gaps = 83/429 (19%) Query: 82 PDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLW 141 PDY++++ QP+D+ I+++L+ Y + DF +F N Y KP A L Sbjct: 111 PDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLE 170 Query: 142 DLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSG 201 ++L QK + +++ E L+ I ++ G Sbjct: 171 KIFL-------QKVASMPQEEQE------------------------LVVTIPKNSHKKG 199 Query: 202 RLISELFQKLPSKVQYP-----DYYAIIKEPIDLKTIAQRIQNGSY------KSIHAMAK 250 ++ L + S Q P + A+ P ++ T I + S KS+H+ Sbjct: 200 AKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP 259 Query: 251 DIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRL 310 LLA A P +Q +K+ K+ A+ L Sbjct: 260 P--LLAVTAA----PPAQPLAKKKGVKR---------------KADTTTPTPTAI----L 294 Query: 311 SAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDV-----SNPFYQLYDTVRSCR 365 + + A GS + A L R E G D S+ +L + ++ C Sbjct: 295 APGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCN 354 Query: 366 NNQGQLIAE-------PFYHL--PSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHL 416 +L+++ PFY S DY+ IK P+ L ++ K++N++Y Sbjct: 355 GILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEF 414 Query: 417 ECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTG 476 D+ LMF N +YN P+ + KLQ V + + ++ + +E G +S+A G Sbjct: 415 AADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMP-DEPLEPGPLPVSTA-MPPG 472 Query: 477 SAKRKSKKN 485 AK S+ + Sbjct: 473 LAKSSSESS 481 Score = 62.4 bits (150), Expect = 3e-09 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 1/166 (0%) Query: 219 DYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKK 278 DY+ IIK P+DL T+ ++++N Y+ A D+ L+ N YN P V A ++ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQD 444 Query: 279 IFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGE 338 +F + A++ + L +S + S+ + + + SES + +E E Sbjct: 445 VFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEE 504 Query: 339 SEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKK 384 E+ES S + ++ +L + +R+ L P P +K+ Sbjct: 505 EESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPI-SKPKRKR 549 Score = 58.5 bits (140), Expect = 5e-08 Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 5/102 (4%) Query: 214 KVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDA 273 K+ PDY+ IIK+P+D+ TI +R++N Y + +D + + N YN+P + A Sbjct: 107 KLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMA 166 Query: 274 NSIKKIFYMKKAEI--EHHEMAKSSLRMSNKRAVQGGRLSAI 313 +++KIF K A + E E+ + + S+K+ G +L+A+ Sbjct: 167 QTLEKIFLQKVASMPQEEQELVVTIPKNSHKK---GAKLAAL 205 Score = 52.0 bits (123), Expect = 5e-06 Identities = 28/82 (34%), Positives = 40/82 (48%) Query: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL 720 LPDY+ IK+PMDM I+ + N Y ++DF MF N YN+P I A L Sbjct: 110 LPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTL 169 Query: 721 HKVLLETRRDLEGDEDSHVPNV 742 K+ L+ + +E V + Sbjct: 170 EKIFLQKVASMPQEEQELVVTI 191 Score = 48.9 bits (115), Expect = 4e-05 Identities = 24/70 (34%), Positives = 36/70 (51%) Query: 520 KKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDA 579 K PDY+KII +PMD+ I+ + N+ Y ++D MF N YN+ + A Sbjct: 107 KLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMA 166 Query: 580 HILEKLLKEK 589 LEK+ +K Sbjct: 167 QTLEKIFLQK 176 Score = 45.8 bits (107), Expect = 3e-04 Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 525 DYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEK 584 DY+ II PMDL ++ + N Y + D++LMF N YN V A L+ Sbjct: 385 DYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQD 444 Query: 585 L-------LKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNE 632 + + ++ E GPLP M K S +S S+ + +++ +E Sbjct: 445 VFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDE 499 Score = 40.8 bits (94), Expect = 0.011 Identities = 18/50 (36%), Positives = 26/50 (52%) Query: 661 LPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPE 710 L DY+ IK PMD+ ++ M Y+D D +MF+N YN P+ Sbjct: 383 LHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPD 432 Score = 40.0 bits (92), Expect = 0.018 Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 9/125 (7%) Query: 785 KPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFF---- 840 K P+ +++ +EN YR F + + + N D ++ A +LQ F Sbjct: 391 KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY 450 Query: 841 IKIRDELCKNGEILLS----PALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREA 896 K+ DE + G + +S P L+ ++ ++ E + +E EED+ EEE+ E+ Sbjct: 451 AKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSE-ESSSESSSEEEEEEDEEDEEEEESES 509 Query: 897 EKSED 901 SE+ Sbjct: 510 SDSEE 514 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 61.6 bits (148), Expect = 6e-09 Identities = 50/122 (40%), Positives = 55/122 (45%), Gaps = 19/122 (15%) Query: 1404 PPGLPP----LQGPVDGLVSMGSMQP---LHPGGP----PPHHLPPGVPG-LPGI-PPPG 1450 PPG PP L P+ G + G P L PG P P LPPG P +PG PPPG Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPG 308 Query: 1451 VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPY-PGPHPAGPPVIQQPTTPMFVA 1509 P G P P G + G LGPP APPP+ PGP P PP P F Sbjct: 309 PP----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH-VNPAFFP 363 Query: 1510 PP 1511 PP Sbjct: 364 PP 365 Score = 58.5 bits (140), Expect = 5e-08 Identities = 47/136 (34%), Positives = 53/136 (38%), Gaps = 30/136 (22%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGV-APMVGTP 1463 PG P G G P P G P P G PG PG P P Q + P+ G P Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267 Query: 1464 APG----------GSPYGQ-QVGVL----------------GPPGQQAPPPYPGPHPAGP 1496 G G P+GQ +G L PP QQ PPP PGP P P Sbjct: 268 NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRP 327 Query: 1497 PVIQQPTTPMFVAPPP 1512 P P P+ +APPP Sbjct: 328 PGPLGP--PLTLAPPP 341 Score = 42.0 bits (97), Expect = 0.005 Identities = 37/120 (30%), Positives = 44/120 (36%), Gaps = 26/120 (21%) Query: 1400 MGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVA-- 1457 +G PPG PP PV G PG PPP PP PG PPG + + Sbjct: 289 LGPLPPGPPP---PVPGYGPP-------PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338 Query: 1458 --PMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQ---PTTPMFVAPPP 1512 P + P PG P P P +P P +G P P T + PPP Sbjct: 339 PPPHLPGPPPGAPP---------PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 Score = 37.7 bits (86), Expect = 0.090 Identities = 33/92 (35%), Positives = 34/92 (36%), Gaps = 11/92 (11%) Query: 1428 PGGPPPHHLPPGVPG---LPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQA 1484 PGG P G G PG P G G A G P P P GQ PP Sbjct: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP--FPAGQT-----PPRPPL 241 Query: 1485 PPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQR 1516 PP P P P GPP Q P PP + R Sbjct: 242 GPPGP-PGPPGPPPPGQVLPPPLAGPPNRGDR 272 Score = 35.4 bits (80), Expect = 0.45 Identities = 27/77 (35%), Positives = 31/77 (40%), Gaps = 14/77 (18%) Query: 1448 PPGVMNQGVAPMVGTPA---PGGSPYGQQV-GVLGPPGQQAPPPYPGPH--------PAG 1495 PPG ++ P G PG P G + G GP G PPP+P P G Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP--PPPFPAGQTPPRPPLGPPG 245 Query: 1496 PPVIQQPTTPMFVAPPP 1512 PP P P V PPP Sbjct: 246 PPGPPGPPPPGQVLPPP 262 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 61.2 bits (147), Expect = 8e-09 Identities = 63/189 (33%), Positives = 75/189 (39%), Gaps = 33/189 (17%) Query: 1385 WRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLP 1444 W N ++ Y GM GG P G P GP + S+ H GG P H P G P Sbjct: 368 WMNSGPSESRPYHGMHGGGPGG--PGGGPHSFPHPLPSLTGGH-GGHPMQHNPNGPPPPW 424 Query: 1445 GIPPPGVMNQGVAPMVGTPAP------GGSPYGQQV-------GVLGPP--GQQAPPP-- 1487 PPP MNQG P P G +P G V G++ PP G PPP Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484 Query: 1488 ---YPGPHPAG--PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEG-----LSAESNSI 1537 P P P+G PP QQ P PPP + S L + + SA + SI Sbjct: 485 PSGQPPPPPSGPLPPWQQQQQQP---PPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541 Query: 1538 SKWDQTLAA 1546 W Q AA Sbjct: 542 PPWQQQQAA 550 Score = 40.0 bits (92), Expect = 0.018 Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 9/57 (15%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVG 1461 PG P +QG +M PL PG PP LPPG P P PPPG + P G Sbjct: 555 PGAPQMQGNP-------TMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMIPPRGG 602 Score = 35.4 bits (80), Expect = 0.45 Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 27/132 (20%) Query: 1400 MGGYPPGLPPLQG----PVDGLVSMGSMQPLHPGGPPP--HHLPPGVP------------ 1441 MG PP PP G P G + Q P PPP + P Sbjct: 475 MGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTT 534 Query: 1442 --GLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVI 1499 G IPP A G P G+P V PPG Q P P P P PP Sbjct: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNP----TMVPLPPGVQPPLPPGAPPPPPPP-- 588 Query: 1500 QQPTTPMFVAPP 1511 P + + PP Sbjct: 589 -PPGSAGMMIPP 599 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 61.2 bits (147), Expect = 8e-09 Identities = 63/189 (33%), Positives = 75/189 (39%), Gaps = 33/189 (17%) Query: 1385 WRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLP 1444 W N ++ Y GM GG P G P GP + S+ H GG P H P G P Sbjct: 368 WMNSGPSESRPYHGMHGGGPGG--PGGGPHSFPHPLPSLTGGH-GGHPMQHNPNGPPPPW 424 Query: 1445 GIPPPGVMNQGVAPMVGTPAP------GGSPYGQQV-------GVLGPP--GQQAPPP-- 1487 PPP MNQG P P G +P G V G++ PP G PPP Sbjct: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484 Query: 1488 ---YPGPHPAG--PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEG-----LSAESNSI 1537 P P P+G PP QQ P PPP + S L + + SA + SI Sbjct: 485 PSGQPPPPPSGPLPPWQQQQQQP---PPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541 Query: 1538 SKWDQTLAA 1546 W Q AA Sbjct: 542 PPWQQQQAA 550 Score = 47.8 bits (112), Expect = 9e-05 Identities = 35/92 (38%), Positives = 38/92 (41%), Gaps = 12/92 (13%) Query: 1405 PGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPA 1464 PG P +QG +M PL PG PP LPPG P P PPPG AP P Sbjct: 555 PGAPQMQGNP-------TMVPLPPGVQPP--LPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605 Query: 1465 ---PGGSPYGQQVGVLGPPGQQAPPPYPGPHP 1493 P +GV G P PP P P P Sbjct: 606 PMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637 Score = 38.5 bits (88), Expect = 0.053 Identities = 39/135 (28%), Positives = 45/135 (33%), Gaps = 26/135 (19%) Query: 1400 MGGYPPGLPPLQG----PVDGLVSMGSMQPLHPGGPPP--HHLPPGVP------------ 1441 MG PP PP G P G + Q P PPP + P Sbjct: 475 MGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTT 534 Query: 1442 --GLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQV--GVLGPPGQQAPPPYPGPHPAGPP 1497 G IPP A G P G+P + GV P APPP P P P Sbjct: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAG 594 Query: 1498 VIQQPTTPMFVAPPP 1512 ++ P P PPP Sbjct: 595 MMYAPPPP----PPP 605 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 61.2 bits (147), Expect = 8e-09 Identities = 44/122 (36%), Positives = 50/122 (40%), Gaps = 10/122 (8%) Query: 1398 GMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVA 1457 G+ G PPG PP P G + L P GPPP P PG P PPG +G Sbjct: 429 GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPP 488 Query: 1458 PMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGP---PVIQQPTTPMFVAPPPKT 1514 P + PAP G P + PG PP P PA P P P + APP Sbjct: 489 PRLPPPAPPGIPPPR-------PGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLI 541 Query: 1515 QR 1516 QR Sbjct: 542 QR 543 Score = 60.8 bits (146), Expect = 1e-08 Identities = 56/149 (37%), Positives = 64/149 (42%), Gaps = 17/149 (11%) Query: 1404 PPGLPPLQ--GPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVG 1461 PP PPL+ GP GL P P G PP PPG+PGL G P P ++ G P Sbjct: 415 PPPAPPLRPPGPPTGL------PPGPPPGAPPFLRPPGMPGLRG-PLPRLLPPGPPPGRP 467 Query: 1462 TPAPGGSPYGQQVG--VLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLH 1519 P G P G G GPP + PP PG P P +++ P P PP L Sbjct: 468 PGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG----LF 523 Query: 1520 SEAYLKYIEGLSAESNSIS--KWDQTLAA 1546 A L LSA N I K D T AA Sbjct: 524 PPAPLPNPGVLSAPPNLIQRPKADDTSAA 552 Score = 52.0 bits (123), Expect = 5e-06 Identities = 42/111 (37%), Positives = 46/111 (41%), Gaps = 20/111 (18%) Query: 1408 PPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVP-GLPGIPPPGV---MNQGVAPMVGTP 1463 PP+ GP PL P PP PPG P GLP PPPG + P + P Sbjct: 405 PPMPGP----------PPLGPPPAPPLR-PPGPPTGLPPGPPPGAPPFLRPPGMPGLRGP 453 Query: 1464 APGGSPYGQQVGVLGPPGQQAPPP---YPGPHPAGPPVIQQPTTPMFVAPP 1511 P P G G PPG PP PGP P GPP P P + PP Sbjct: 454 LPRLLPPGPPPG--RPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPP 502 Score = 36.6 bits (83), Expect = 0.20 Identities = 30/100 (30%), Positives = 37/100 (37%), Gaps = 25/100 (25%) Query: 1415 DGLVSMGSMQPLHPGGPPPHHLP-PGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQ 1473 DG + S Q P PP + P +PG P + PP PAP P G Sbjct: 381 DGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPP-------------PAPPLRPPG-- 425 Query: 1474 VGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPK 1513 PP PGP P PP ++ P P P P+ Sbjct: 426 -----PPTGLP----PGPPPGAPPFLRPPGMPGLRGPLPR 456 Score = 33.1 bits (74), Expect = 2.2 Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 1432 PPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPY-GQQVGVLGPPGQQAPPPYPG 1490 P + L +P LPG PP ++ + A T A P G V L PPG++ P P PG Sbjct: 148 PSNILIQDIP-LPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRL-PPGRKPPGPPPG 205 Query: 1491 PHPAGPPVIQ 1500 P P P V+Q Sbjct: 206 PPP--PQVVQ 213 >gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] Length = 832 Score = 60.5 bits (145), Expect = 1e-08 Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 22/222 (9%) Query: 384 KYPDYYQQIKMPISLQQIRTKLKN--QEYETLDHLECDLN--LMFENAKRYNVPNSAIYK 439 K + ++IK+P +TK ++YE + C+LN + + I K Sbjct: 618 KKQGFSKEIKIP------KTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIK 671 Query: 440 RVLKLQQVMQAKK-------KELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMK 492 ++++ +Q K K+ R+ IE + + +G K K ++ + Sbjct: 672 KLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQ---- 727 Query: 493 ILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEE 552 L++ + + + FM + + P YY++I PMDLK + ++N Y ++ Sbjct: 728 -LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786 Query: 553 GMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELG 594 + D++ +F N + YN S+ Y A+ILEK K KE G Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAG 828 Score = 60.1 bits (144), Expect = 2e-08 Identities = 28/79 (35%), Positives = 46/79 (58%) Query: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267 F + + + P YY +I+ P+DLKT+++R++N Y S D+ + N K YN P S Sbjct: 748 FMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPES 807 Query: 268 QVFKDANSIKKIFYMKKAE 286 + +K AN ++K F+ K E Sbjct: 808 EYYKCANILEKFFFSKIKE 826 Score = 55.8 bits (133), Expect = 3e-07 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 356 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 414 QLY T++S + A PF + + P YY+ I+ P+ L+ + +LKN+ Y + Sbjct: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786 Query: 415 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 454 DL +F N K YN P S YK L++ +K KE Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826 Score = 55.8 bits (133), Expect = 3e-07 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%) Query: 52 ELYNTIRDYKDE-QGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110 +LY+T++ + + F+ KR P YYEV+ P+DL + ++LK Y Sbjct: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786 Query: 111 LLTADFQLLFNNAKSYYKPDSPEYKAA 137 L AD Q +F N K Y P+S YK A Sbjct: 787 LFMADLQRVFTNCKEYNPPESEYYKCA 813 Score = 47.8 bits (112), Expect = 9e-05 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 4/114 (3%) Query: 611 RKSGISPK-KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTI 668 R++G P K K P +++Y +K+ + SA F+ R+E P YY I Sbjct: 707 RETGWKPSGKEKSKEPRDP--DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI 764 Query: 669 KKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 722 + PMD++ + + Y + D +F N YN PES YK A +L K Sbjct: 765 RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK 818 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 69,026,902 Number of Sequences: 37866 Number of extensions: 3895317 Number of successful extensions: 40167 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 350 Number of HSP's successfully gapped in prelim test: 839 Number of HSP's that attempted gapping in prelim test: 22638 Number of HSP's gapped (non-prelim): 9284 length of query: 1602 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1486 effective length of database: 13,855,062 effective search space: 20588622132 effective search space used: 20588622132 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.