Search of human proteins with 30102946

Search of human proteins with 30102946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo
sapiens]
         (82 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo ...   167   2e-42
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ...   159   5e-40
gi|209862841 islet cell autoantigen 1 [Homo sapiens]                  102   9e-23
gi|94721350 islet cell autoantigen 1 [Homo sapiens]                   102   9e-23
gi|12545395 islet cell autoantigen 1 [Homo sapiens]                   102   9e-23
gi|224458301 family with sequence similarity 186, member A [Homo...    29   0.71 
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]      28   1.2  
gi|162287219 prune homolog 2 [Homo sapiens]                            28   2.1  
gi|87240000 5,10-methylenetetrahydrofolate reductase [Homo sapiens]    28   2.1  
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s...    27   2.7  
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...    27   2.7  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 27   3.5  
gi|38044112 restin isoform b [Homo sapiens]                            27   4.6  
gi|4506751 restin isoform a [Homo sapiens]                             27   4.6  
gi|116812628 coiled-coil domain containing 67 [Homo sapiens]           26   6.0  
gi|32698686 N-acetylgalactosaminyltransferase 5 [Homo sapiens]         26   7.8  

>gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo
          sapiens]
          Length = 82

 Score =  167 bits (422), Expect = 2e-42
 Identities = 82/82 (100%), Positives = 82/82 (100%)

Query: 1  MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
          MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ
Sbjct: 1  MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60

Query: 61 ETCTELLKIIEKYQLRLNGMKS 82
          ETCTELLKIIEKYQLRLNGMKS
Sbjct: 61 ETCTELLKIIEKYQLRLNGMKS 82


>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
          sapiens]
          Length = 482

 Score =  159 bits (402), Expect = 5e-40
 Identities = 78/78 (100%), Positives = 78/78 (100%)

Query: 1  MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60
          MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ
Sbjct: 1  MDSFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQ 60

Query: 61 ETCTELLKIIEKYQLRLN 78
          ETCTELLKIIEKYQLRLN
Sbjct: 61 ETCTELLKIIEKYQLRLN 78


>gi|209862841 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score =  102 bits (253), Expect = 9e-23
 Identities = 48/72 (66%), Positives = 59/72 (81%)

Query: 6  QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
          Q R   ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72

Query: 66 LLKIIEKYQLRL 77
          L K I  YQ R+
Sbjct: 73 LSKAIVLYQKRI 84


>gi|94721350 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score =  102 bits (253), Expect = 9e-23
 Identities = 48/72 (66%), Positives = 59/72 (81%)

Query: 6  QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
          Q R   ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72

Query: 66 LLKIIEKYQLRL 77
          L K I  YQ R+
Sbjct: 73 LSKAIVLYQKRI 84


>gi|12545395 islet cell autoantigen 1 [Homo sapiens]
          Length = 483

 Score =  102 bits (253), Expect = 9e-23
 Identities = 48/72 (66%), Positives = 59/72 (81%)

Query: 6  QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
          Q R   ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72

Query: 66 LLKIIEKYQLRL 77
          L K I  YQ R+
Sbjct: 73 LSKAIVLYQKRI 84


>gi|224458301 family with sequence similarity 186, member A [Homo
           sapiens]
          Length = 2351

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 8/70 (11%)

Query: 10  EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAE----LDAKL-EVFHSVQETCT 64
           E  ++++  +++K     + F K T  KE+E L  ++AE    + AK+ E F  V ET T
Sbjct: 671 EFQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKRAEAEKLGIIKAKMEEYFQKVAETVT 730

Query: 65  ELLKIIEKYQ 74
              KI+ KY+
Sbjct: 731 ---KILRKYK 737


>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
          Length = 4490

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/62 (24%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 17  RRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIEKYQLR 76
           +  Q  + KT+++  +++G+K  E    S+  +  K E F    E  TE++ +++ Y   
Sbjct: 329 KEYQASFHKTRKLISESSGEKSFE---VSEMYIFGKFEAFCKRLEKITEMITVVQTYSTL 385

Query: 77  LN 78
            N
Sbjct: 386 SN 387


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 16/40 (40%), Positives = 19/40 (47%)

Query: 32   KATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIE 71
            + T K ED H +  D  L  + E  HS  ETC E   I E
Sbjct: 2535 RCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAE 2574


>gi|87240000 5,10-methylenetetrahydrofolate reductase [Homo sapiens]
          Length = 656

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 14/28 (50%), Positives = 21/28 (75%), Gaps = 1/28 (3%)

Query: 51  AKLEVFHSVQETCTELLKIIEKYQLRLN 78
           A LE F S +ET   LL++++KY+LR+N
Sbjct: 511 AYLEFFTS-RETAEALLQVLKKYELRVN 537


>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
           sapiens]
          Length = 874

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 10/48 (20%), Positives = 26/48 (54%)

Query: 10  EDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFH 57
           +D +    +  +KY+   +  +  + KK++ HL  +D ++D + + F+
Sbjct: 128 KDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFY 175


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 3   SFGQPRPEDNQSVVRRMQKKYWKTKQVFIKATGK 36
           S G+P P   Q++VRR+Q+ Y    + F + TG+
Sbjct: 273 SKGRPHPRVPQALVRRLQEFYRPFNRRFYQMTGQ 306


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 5/43 (11%)

Query: 25   KTKQVFIKATGKKEDEHL-----VASDAELDAKLEVFHSVQET 62
            K  QV++ + GKK+ EH      VA     ++ + + HS+ ET
Sbjct: 2541 KENQVYVLSEGKKQQEHQPYSVNVAESMSRESDISLGHSLGET 2583


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 6/48 (12%)

Query: 36  KKEDEHLVASD------AELDAKLEVFHSVQETCTELLKIIEKYQLRL 77
           K ED+HLV  +       E + K++    +Q  C E  K+I+ +  +L
Sbjct: 673 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQL 720


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 14/48 (29%), Positives = 24/48 (50%), Gaps = 6/48 (12%)

Query: 36  KKEDEHLVASD------AELDAKLEVFHSVQETCTELLKIIEKYQLRL 77
           K ED+HLV  +       E + K++    +Q  C E  K+I+ +  +L
Sbjct: 708 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQL 755


>gi|116812628 coiled-coil domain containing 67 [Homo sapiens]
          Length = 604

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 14/64 (21%)

Query: 18  RMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTELLKIIEKYQLRL 77
           R + + W  +++  +        HL++ DA+   KL     + E C +  K  + YQ +L
Sbjct: 147 RAKSREWDKQEILYQT-------HLISLDAQ--QKL-----LSEKCNQFQKQAQSYQTQL 192

Query: 78  NGMK 81
           NG K
Sbjct: 193 NGKK 196


>gi|32698686 N-acetylgalactosaminyltransferase 5 [Homo sapiens]
          Length = 940

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 11/35 (31%), Positives = 19/35 (54%)

Query: 25  KTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSV 59
           KTK +F K  GK + +H+  + +E+ +     H V
Sbjct: 342 KTKTIFPKVLGKSQSKHISRNRSEMSSSSLAPHRV 376


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,931,136
Number of Sequences: 37866
Number of extensions: 99992
Number of successful extensions: 397
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 385
Number of HSP's gapped (non-prelim): 18
length of query: 82
length of database: 18,247,518
effective HSP length: 54
effective length of query: 28
effective length of database: 16,202,754
effective search space: 453677112
effective search space used: 453677112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.