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Search of human proteins with 30089926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
(843 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 1776 0.0
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 1393 0.0
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 1232 0.0
gi|124244083 F-box protein 10 [Homo sapiens] 175 1e-43
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] 63 1e-09
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 50 7e-06
gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] 47 7e-05
gi|22749363 F-box protein 15 isoform 1 [Homo sapiens] 47 1e-04
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 47 1e-04
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 47 1e-04
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 44 8e-04
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 44 8e-04
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 42 0.002
gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens] 42 0.002
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 42 0.002
gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [... 42 0.003
gi|67003566 F-box protein 48 [Homo sapiens] 42 0.003
gi|48928044 F-box only protein 8 [Homo sapiens] 41 0.005
gi|154426322 ubiquitin protein ligase E3 component n-recognin 7 ... 40 0.009
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 40 0.009
gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens] 40 0.009
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 40 0.012
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 40 0.012
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c... 39 0.015
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c... 39 0.015
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 39 0.015
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 39 0.020
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi... 39 0.026
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 38 0.034
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 38 0.034
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 1776 bits (4599), Expect = 0.0
Identities = 843/843 (100%), Positives = 843/843 (100%)
Query: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF
Sbjct: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
Query: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE
Sbjct: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
Query: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN
Sbjct: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
Query: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT
Sbjct: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
Query: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP
Sbjct: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
Query: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
Query: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN
Sbjct: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
Query: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT
Sbjct: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
Query: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG 600
GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG
Sbjct: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG 600
Query: 601 QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGL 660
QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGL
Sbjct: 601 QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGL 660
Query: 661 LEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGL 720
LEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGL
Sbjct: 661 LEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGL 720
Query: 721 FLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAI 780
FLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAI
Sbjct: 721 FLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAI 780
Query: 781 CVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTL 840
CVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTL
Sbjct: 781 CVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTL 840
Query: 841 QHN 843
QHN
Sbjct: 841 QHN 843
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 1393 bits (3606), Expect = 0.0
Identities = 663/682 (97%), Positives = 670/682 (98%), Gaps = 5/682 (0%)
Query: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF
Sbjct: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
Query: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE
Sbjct: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
Query: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN
Sbjct: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
Query: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT
Sbjct: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
Query: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP
Sbjct: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
Query: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
Query: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN
Sbjct: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
Query: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT
Sbjct: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
Query: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG 600
GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG
Sbjct: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGG 600
Query: 601 QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGL 660
QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRG+
Sbjct: 601 QNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGI 660
Query: 661 -----LEENDIFRNAQAGVLIS 677
L +N +F + ++I+
Sbjct: 661 VVNFALVKNPVFHYSSISLMIN 682
Score = 308 bits (790), Expect = 1e-83
Identities = 143/337 (42%), Positives = 217/337 (64%)
Query: 404 ANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGN 463
A PT+ C I + G+Y+ + +G + +N+I N AG+W+ ++ +P IR N I +G
Sbjct: 312 ACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGR 371
Query: 464 QGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVI 523
GV+ F G G E +I+ N +AG +++ + P V +IH GQ GGIYVHEKG+G
Sbjct: 372 DVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQF 431
Query: 524 EENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQ 583
EN++Y+N AGVW+T+ S P +R N I +G Q GVY + +G G++E NDIY + +G+Q
Sbjct: 432 IENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQ 491
Query: 584 IRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKI 643
IRT S P +R NKI GQ+GGI V+ G G IE+NE++ N +AGVW+ T S P LRRN+I
Sbjct: 492 IRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRI 551
Query: 644 HDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHA 703
H G+ G+ ++ G G+LE+NDI+ + +GV I T S+P +R+N+I+ G GI + N
Sbjct: 552 HSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSG 611
Query: 704 TATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQD 740
+E N+IF+N G+++ + N T++ NKI + +D
Sbjct: 612 LGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRD 648
Score = 147 bits (372), Expect = 3e-35
Identities = 92/297 (30%), Positives = 137/297 (46%), Gaps = 66/297 (22%)
Query: 485 NALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTP 544
NA ++I N PI+ H I G V GQG + P
Sbjct: 275 NAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQG--------------------ACP 314
Query: 545 VLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRN--------- 595
++ I + VG+Y D+ G+ EDN+I N+ +G+ ++ NP IRRN
Sbjct: 315 TIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVG 374
Query: 596 -------------------------------------KIWGGQNGGILVYNSGLGCIEDN 618
+I GQ GGI V+ G G +N
Sbjct: 375 VFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIEN 434
Query: 619 EIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLIST 678
+I+ N AGVWI ++S+PT+R N I +G GG+ IF GRGL+E NDI+ NA AG+ I T
Sbjct: 435 KIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRT 494
Query: 679 NSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKI 735
NS PI+R N+I DG GI + +E N++++N G+++ +G ++ N+I
Sbjct: 495 NSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRI 551
Score = 80.9 bits (198), Expect = 5e-15
Identities = 49/155 (31%), Positives = 73/155 (47%), Gaps = 23/155 (14%)
Query: 587 GSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDG 646
G+ P I+ I +N G+ + + G EDNEI +NA+AG+W+K NP +RRN IH G
Sbjct: 311 GACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHG 370
Query: 647 RDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATAT 706
RD G+ F+ G G E +I RN AG E+ +A T
Sbjct: 371 RDVGVFTFDHGMGYFESCNIHRNR-----------------------IAGFEVKAYANPT 407
Query: 707 LEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDA 741
+ +I + + GG+++ +NKI N A
Sbjct: 408 VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFA 442
>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
Length = 585
Score = 1232 bits (3187), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ
Sbjct: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
Query: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF
Sbjct: 61 DLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
Query: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE
Sbjct: 121 EYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRE 180
Query: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN
Sbjct: 181 NMLYYDTIEDALGGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIEN 240
Query: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT
Sbjct: 241 TRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCT 300
Query: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP
Sbjct: 301 VGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNP 360
Query: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGG 420
Query: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN
Sbjct: 421 IYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGN 480
Query: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT
Sbjct: 481 DIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT 540
Query: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIR 585
GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIR
Sbjct: 541 GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIR 585
Score = 264 bits (675), Expect = 2e-70
Identities = 121/273 (44%), Positives = 178/273 (65%)
Query: 404 ANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGN 463
A PT+ C I + G+Y+ + +G + +N+I N AG+W+ ++ +P IR N I +G
Sbjct: 312 ACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGR 371
Query: 464 QGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVI 523
GV+ F G G E +I+ N +AG +++ + P V +IH GQ GGIYVHEKG+G
Sbjct: 372 DVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQF 431
Query: 524 EENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQ 583
EN++Y+N AGVW+T+ S P +R N I +G Q GVY + +G G++E NDIY + +G+Q
Sbjct: 432 IENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQ 491
Query: 584 IRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKI 643
IRT S P +R NKI GQ+GGI V+ G G IE+NE++ N +AGVW+ T S P LRRN+I
Sbjct: 492 IRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRI 551
Query: 644 HDGRDGGICIFNGGRGLLEENDIFRNAQAGVLI 676
H G+ G+ ++ G G+LE+NDI+ + +GV I
Sbjct: 552 HSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQI 584
Score = 223 bits (567), Expect = 8e-58
Identities = 116/330 (35%), Positives = 181/330 (54%), Gaps = 20/330 (6%)
Query: 391 HRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNS 450
H N E+ +P + C I T G V G+G +
Sbjct: 273 HHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQG--------------------A 312
Query: 451 DPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQH 510
PTI+ +I + G+YI +G+ E N+I NALAGI ++ + PI+R N IH G+
Sbjct: 313 CPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRD 372
Query: 511 GGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLE 570
G++ + G G E ++ N +AG V + P + R IH G+ G+Y ++ G G
Sbjct: 373 VGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFI 432
Query: 571 DNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWI 630
+N IY + ++GV I + S+P IR N I+ G GG+ ++ G G IE N+I+ NA+AG+ I
Sbjct: 433 ENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQI 492
Query: 631 KTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIF 690
+T+S P +R NKIHDG+ GGI + G+G++EEN+++ N AGV ++T S P+LR+NRI
Sbjct: 493 RTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIH 552
Query: 691 DGFAAGIEITNHATATLEGNQIFNNRFGGL 720
G G+ ++ LE N I+N+ + G+
Sbjct: 553 SGKQVGVYFYDNGHGVLEDNDIYNHMYSGV 582
Score = 214 bits (545), Expect = 3e-55
Identities = 97/240 (40%), Positives = 154/240 (64%)
Query: 496 SCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGK 555
+CP ++H I D ++ G+Y+ + QG+ E+NE+ +N LAG+WV P++RRN IH G+
Sbjct: 312 ACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGR 371
Query: 556 QVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCI 615
VGV+ +D+G G E +I+ + +G +++ +NP + R +I GQ GGI V+ G G
Sbjct: 372 DVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQF 431
Query: 616 EDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVL 675
+N+I+ N AGVWI ++S+PT+R N I +G GG+ IF GRGL+E NDI+ NA AG+
Sbjct: 432 IENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQ 491
Query: 676 ISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKI 735
I TNS PI+R N+I DG GI + +E N++++N G+++ +G ++ N+I
Sbjct: 492 IRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRI 551
Score = 80.9 bits (198), Expect = 5e-15
Identities = 49/155 (31%), Positives = 73/155 (47%), Gaps = 23/155 (14%)
Query: 587 GSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDG 646
G+ P I+ I +N G+ + + G EDNEI +NA+AG+W+K NP +RRN IH G
Sbjct: 311 GACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHG 370
Query: 647 RDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATAT 706
RD G+ F+ G G E +I RN AG E+ +A T
Sbjct: 371 RDVGVFTFDHGMGYFESCNIHRNR-----------------------IAGFEVKAYANPT 407
Query: 707 LEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDA 741
+ +I + + GG+++ +NKI N A
Sbjct: 408 VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFA 442
>gi|124244083 F-box protein 10 [Homo sapiens]
Length = 956
Score = 175 bits (444), Expect = 1e-43
Identities = 128/443 (28%), Positives = 200/443 (45%), Gaps = 45/443 (10%)
Query: 316 IKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGV 375
I+ C D + G+++ H + E N N A + N I+ RN I+ R G+
Sbjct: 432 IRKCLFRDGKG-GVFVCSHGRAKMEGNIFRNLTYAVRCIHN-SKIIMLRNDIYRCRASGI 489
Query: 376 FTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENK 435
F G G NI+ N AG +++ +NP ++ +IHHG GI V G+G N+
Sbjct: 490 FLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQ 549
Query: 436 IYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTN 495
I++N AG++I + +P + GN IF G G+ + +G+GLI N I N G+ IR
Sbjct: 550 IFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRG 609
Query: 496 SCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGK 555
P++R N I G G+ V ++G+G+IE N +Y+N GVW+ + S P + N +
Sbjct: 610 GIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNG 669
Query: 556 QVGVY--------------------FYDNGHGVL---------------------EDNDI 574
GV F ++G +L E N I
Sbjct: 670 LYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSI 729
Query: 575 YNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGC-IEDNEIFDNAMAGVWIKTD 633
++ SG+ +++ + N I + GI V S + +N I N +GV ++
Sbjct: 730 NHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQ 789
Query: 634 SNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGF 693
LR N I+D R GI I G ++ ENDI N +G+ + S + KNRI
Sbjct: 790 CKVELRGNGIYDNRGHGI-ITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVIKNRIHSFR 848
Query: 694 AAGIEITNHATATLEGNQIFNNR 716
A GI + A A ++ N IF +
Sbjct: 849 AYGIAVRGRAKALVQENIIFQGK 871
Score = 160 bits (404), Expect = 6e-39
Identities = 110/349 (31%), Positives = 172/349 (49%), Gaps = 17/349 (4%)
Query: 399 EVKAYANPT----VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTI 454
E A AN + +C G+ GG++V GR + +E I+ N V NS +
Sbjct: 419 EAMALANSVQGCLIRKCLFRDGK-GGVFVCSHGRAK-MEGNIFRNLTYAVRCIHNSKIIM 476
Query: 455 RGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIY 514
N I+ G+++ +G GLI GN+IY NA AG+ IR S P++ N+IH G GI
Sbjct: 477 LRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIV 536
Query: 515 VHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDI 574
V G+G+I N+++SN AG+++ PV+ N I G+ G+ +NG G++ +N I
Sbjct: 537 VLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVI 596
Query: 575 YNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDS 634
+ + GV IR G P +R N I G + G++V + G G IE N I+ N GVW+ + S
Sbjct: 597 RENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSS 656
Query: 635 NPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRI---FD 691
P + N + G+ +F+ G +++ R +A S + IL + + D
Sbjct: 657 LPHVTSNHVSYNGLYGVAVFSQKDG---SSELPRGHRAQENFSEDGDAILWETELEKEDD 713
Query: 692 GFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQD 740
I I A +E N I +N GL++ S + + N I N D
Sbjct: 714 PLRRPITI-----ALVESNSINHNGASGLYVQSSEALHVITNVIHANGD 757
Score = 154 bits (388), Expect = 4e-37
Identities = 117/400 (29%), Positives = 187/400 (46%), Gaps = 26/400 (6%)
Query: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVV--RCEIHHGQT 418
+IR+ G+ GVF HG E NI RN + V+ N ++ R +I+ +
Sbjct: 431 LIRKCLFRDGKG-GVFVCSHGRAKMEG-NIFRNLT--YAVRCIHNSKIIMLRNDIYRCRA 486
Query: 419 GGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIE 478
GI++ +G G N IY N AGV I S+P I N I +G + G+ + G+G+G+I
Sbjct: 487 SGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIR 546
Query: 479 GNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWV 538
N I+ N AGI I + P+V N I G+ GI V+E G+G+I EN + N GV +
Sbjct: 547 NNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDI 606
Query: 539 TTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIW 598
G PVLR N I G GV D G G++E N IY + GV + + S P + N +
Sbjct: 607 RRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVS 666
Query: 599 GGQNGGILVYNSGLGCIE-------DNEIFDNAMAGVW---IKTDSNPTLR--------R 640
G+ V++ G E ++ A +W ++ + +P R
Sbjct: 667 YNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVES 726
Query: 641 NKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPI-LRKNRIFDGFAAGIEI 699
N I+ G+ + + + N I N G+ ++ +S P + N I +G+++
Sbjct: 727 NSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKV 786
Query: 700 TNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQ 739
L GN I++NR G+ + G + + +N I+ N+
Sbjct: 787 EAQCKVELRGNGIYDNRGHGI-ITKGDSTIVIENDIIGNR 825
Score = 91.3 bits (225), Expect = 3e-18
Identities = 90/374 (24%), Positives = 149/374 (39%), Gaps = 30/374 (8%)
Query: 273 HHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYIT 332
HH + + N II + I S G + G P + +I G+ +
Sbjct: 528 HHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGN---PVVSGNHIFKGRAAGIAVN 584
Query: 333 DHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHR 392
++ +G+ +N I N G+ ++ G P++R N I G GV D G G E I+
Sbjct: 585 ENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYA 644
Query: 393 NRIAGFEVKAYANPTVVRCEIHHGQTGGIYV-------HEKGRGQFIENKIYANNFAGVW 445
N+ G + + + P V + + G+ V E RG + + A +W
Sbjct: 645 NKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILW 704
Query: 446 IT---SNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRH 502
T DP R +I L+E N I N +G+ ++++ V
Sbjct: 705 ETELEKEDDPLRRPITI---------------ALVESNSINHNGASGLYVQSSEALHVIT 749
Query: 503 NKIHDGQHGGIYVHEKGQGV-IEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYF 561
N IH GI V + Q + N + N +GV V LR N I+ + G+
Sbjct: 750 NVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIIT 809
Query: 562 YDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIF 621
+ V+E NDI + SG+Q+ S+ K+ +N+I + GI V +++N IF
Sbjct: 810 KGDSTIVIE-NDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIF 868
Query: 622 DNAMAGVWIKTDSN 635
+ + SN
Sbjct: 869 QGKTSKTIFQQISN 882
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 603 GGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLE 662
GG+ V + G +E N IF N V +S + RN I+ R GI + G GL+
Sbjct: 442 GGVFVCSHGRAKMEGN-IFRNLTYAVRCIHNSKIIMLRNDIYRCRASGIFLRLEGGGLIA 500
Query: 663 ENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFL 722
N+I+ NA+AGV I S+P++ N+I G +GI + + + NQIF+N+ G+++
Sbjct: 501 GNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYI 560
Query: 723 ASGVNVTMKDNKIMNNQDA 741
N + N I + A
Sbjct: 561 LYHGNPVVSGNHIFKGRAA 579
Score = 35.0 bits (79), Expect = 0.29
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSE--LANDPILWKRLYMEVFEYTRPMMHPEPG 132
LP E+ I +YL DL R + VC+ + E L+ D W++L + E P +P
Sbjct: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQP- 64
Query: 133 KFYQINPEEYEHPNPWKESFQQLY 156
+ PE W+E+F+Q Y
Sbjct: 65 ---DVEPES------WREAFKQHY 79
>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
Length = 5183
Score = 63.2 bits (152), Expect = 1e-09
Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 739 QDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIR 798
+D+ E ++ C + I+ H +Y CHTC D +C C K CH+ H++ + +
Sbjct: 1650 EDSDEDSLCNKLCTFTITQKEFMNQH-WYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAK 1708
Query: 799 HDRFFCDCGAG------TLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQH 842
+ FFCDCGA L +G + ++ + S P I + ++H
Sbjct: 1709 YGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPRISESLVRH 1758
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 11/124 (8%)
Query: 3 AEESGPGAQNSPYQLRRKTLLPKRTACPTK----NSMEGASTSTTENFG------HRAKR 52
A+++ +++S +R + CP + G+STS++ G H
Sbjct: 34 AQKNVATSEDSDLSMRTLSTPSPALICPPNLPGFQNGRGSSTSSSSITGETVAMVHSPPP 93
Query: 53 ARVSGKSQDLSAAPA-EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPIL 111
R++ L++ P EQ ++LPD +++IFS+L LCR A VC+R+ LA DP L
Sbjct: 94 TRLTHPLIRLASRPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRL 153
Query: 112 WKRL 115
W+ +
Sbjct: 154 WRTI 157
>gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]
Length = 510
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/78 (34%), Positives = 35/78 (44%)
Query: 47 GHRAKRARVSGKSQDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELA 106
G A R G S+ + +P E++LKIFSYL L CV +RF LA
Sbjct: 49 GSAALRCHAGGGQHWESSFSCCSGFLDGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLA 108
Query: 107 NDPILWKRLYMEVFEYTR 124
ND +W +Y F R
Sbjct: 109 NDNFIWIGIYSTAFSPAR 126
>gi|22749363 F-box protein 15 isoform 1 [Homo sapiens]
Length = 434
Score = 46.6 bits (109), Expect = 1e-04
Identities = 22/50 (44%), Positives = 28/50 (56%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTR 124
+P E++LKIFSYL L CV +RF LAND +W +Y F R
Sbjct: 1 MPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIWIGIYSTAFSPAR 50
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 46.6 bits (109), Expect = 1e-04
Identities = 22/42 (52%), Positives = 28/42 (66%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLY 116
LP EV+L IFSYL Q+LCR + V ++S+L LWK LY
Sbjct: 82 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY 123
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 46.6 bits (109), Expect = 1e-04
Identities = 22/42 (52%), Positives = 28/42 (66%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLY 116
LP EV+L IFSYL Q+LCR + V ++S+L LWK LY
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLY 249
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 43.5 bits (101), Expect = 8e-04
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)
Query: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130
+ LPDE++L IFS L +L + + VCKR+ LA+D LW+ L + T +HP+
Sbjct: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 43.5 bits (101), Expect = 8e-04
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)
Query: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130
+ LPDE++L IFS L +L + + VCKR+ LA+D LW+ L + T +HP+
Sbjct: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
Length = 326
Score = 42.4 bits (98), Expect = 0.002
Identities = 19/47 (40%), Positives = 31/47 (65%)
Query: 74 KLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
+LPD V+L+IFSYL +D R + VC R+ L +D LW+ + + ++
Sbjct: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY 52
>gi|24308129 F-box and WD repeat domain containing 5 [Homo sapiens]
Length = 566
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKF 134
LPD +V +IF L D+ A VC+++ ++ D LW+ + ++
Sbjct: 9 LPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFY---------------RY 53
Query: 135 YQINPEEYEHP--NPWKESFQQLY 156
YQ+ + HP W E FQ+LY
Sbjct: 54 YQVARDVPRHPAAMSWYEEFQRLY 77
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/57 (38%), Positives = 37/57 (64%), Gaps = 2/57 (3%)
Query: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTR 124
E + +KLP E++L+IFS+L LCR A V + ++ LA D W+R+ ++F++ R
Sbjct: 21 EAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRI--DLFDFQR 75
>gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [Homo
sapiens]
Length = 2799
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 765 DFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIR-HDRFFCDCGAGTLSNPCTLAGEPTH 823
D + C TC + C C + CH+GHD + R +CDC +AG+ +
Sbjct: 1192 DIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWE-KCKCKTLIAGQKSA 1250
Query: 824 DTDTLY 829
D LY
Sbjct: 1251 RLDLLY 1256
>gi|67003566 F-box protein 48 [Homo sapiens]
Length = 155
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/130 (26%), Positives = 53/130 (40%), Gaps = 12/130 (9%)
Query: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSE-LANDPILWKRLYMEVFEYTRPMMHPEP 131
E LP E+ KIFS L + LCRA+ C+ +++ + N LWK M V R +
Sbjct: 36 ELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVRAVCRREI---- 91
Query: 132 GKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDA 191
++ E W+ + Y+ + VK + YSN + Y D
Sbjct: 92 -------DDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADT 144
Query: 192 LGGVQEAHFD 201
G + EA +
Sbjct: 145 WGEILEAELE 154
>gi|48928044 F-box only protein 8 [Homo sapiens]
Length = 319
Score = 40.8 bits (94), Expect = 0.005
Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRL 115
E LP E+ I SYL DLC A+CV + +LAND +LW+ L
Sbjct: 72 EMLPPELSFTILSYLNATDLCLASCV---WQDLANDELLWQGL 111
>gi|154426322 ubiquitin protein ligase E3 component n-recognin 7
(putative) isoform 2 [Homo sapiens]
Length = 425
Score = 40.0 bits (92), Expect = 0.009
Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 6/95 (6%)
Query: 722 LASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRN--A 779
+ S V+V +D ++ N A+ +C Y S S Y C TC
Sbjct: 17 VVSLVDVLEEDEELENEACAVLGGSDSEKCSY---SQGSVKRQALYACSTCTPEGEEPAG 73
Query: 780 ICVNCIKKCHQGHDV-EFIRHDRFFCDCGAGTLSN 813
IC+ C +CH H + E F CDCG N
Sbjct: 74 ICLACSYECHGSHKLFELYTKRNFRCDCGNSKFKN 108
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/54 (38%), Positives = 34/54 (62%)
Query: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFE 121
E + +KLP E++L+IFS+L LCR A + K ++ LA D W+R+ + F+
Sbjct: 8 EGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQ 61
>gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens]
Length = 653
Score = 40.0 bits (92), Expect = 0.009
Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 16/151 (10%)
Query: 518 KGQGVIEENEVYSNTLAGVWVTTGSTPV--LRRNRIHSGKQVGVYFYDNGHGVLEDNDIY 575
KG G EE + S +V + + V + + I G G+ ++GH LE N I
Sbjct: 445 KGVGKREEIMITSEPSRDSFVVSKADNVKLMHLSLIQQGTVDGIVVVESGHMTLE-NCIL 503
Query: 576 NHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIF-----------DNA 624
+GV + TG+ I ++I G Q G+ +Y + +E NEI +
Sbjct: 504 KCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILERNEIHHCNNLRTSNSSKST 563
Query: 625 MAGVWIKTDSNPTLR--RNKIHDGRDGGICI 653
+ GV +K P L+ N I+ + G+ I
Sbjct: 564 LGGVNMKVLPAPKLKMTNNHIYSNKGYGVSI 594
Score = 31.2 bits (69), Expect = 4.2
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 631 KTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIF 690
K D+ + + I G GI + G LE N I + GV + T + + + I
Sbjct: 468 KADNVKLMHLSLIQQGTVDGIVVVESGHMTLE-NCILKCEGTGVCVLTGAALTITDSEIT 526
Query: 691 DGFAAGIEITNHATATLEGNQI 712
AG+E+ + A LE N+I
Sbjct: 527 GAQGAGVELYPGSIAILERNEI 548
Score = 31.2 bits (69), Expect = 4.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 315 TIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHH 369
T+++C I CE G+ + A D+EI+ AG+ + I+ RN IHH
Sbjct: 497 TLENC-ILKCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILERNEIHH 550
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 39.7 bits (91), Expect = 0.012
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
+V E GP + + R+T + G S + G R++ A +
Sbjct: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
Query: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 39.7 bits (91), Expect = 0.012
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 1 MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60
+V E GP + + R+T + G S + G R++ A +
Sbjct: 47 LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
Query: 61 DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112
+ P E +++P E++++IF L+ D L RAA VC+R+ E A+ P LW
Sbjct: 98 APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
component n-recognin 5 isoform 2 [Homo sapiens]
Length = 2277
Score = 39.3 bits (90), Expect = 0.015
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
Query: 765 DFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIR-HDRFFCDCGAGTLSNPCTLAGEPTH 823
D + C TC + C C CH+GHD + R +CDC +AG+ +
Sbjct: 671 DIFECRTCGLLESLCCCTECAGVCHKGHDWKLKRTSPTAYCDCWE-KCKCKTLIAGQKSA 729
Query: 824 DTDTLY 829
D LY
Sbjct: 730 RLDLLY 735
>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
component n-recognin 5 isoform 1 [Homo sapiens]
Length = 2796
Score = 39.3 bits (90), Expect = 0.015
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 2/66 (3%)
Query: 765 DFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIR-HDRFFCDCGAGTLSNPCTLAGEPTH 823
D + C TC + C C CH+GHD + R +CDC +AG+ +
Sbjct: 1190 DIFECRTCGLLESLCCCTECAGVCHKGHDWKLKRTSPTAYCDCWE-KCKCKTLIAGQKSA 1248
Query: 824 DTDTLY 829
D LY
Sbjct: 1249 RLDLLY 1254
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 39.3 bits (90), Expect = 0.015
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Query: 17 LRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSAAPAEQYLQEKLP 76
++ K +L +T+ N +E + + + G + + S S L P Y +KLP
Sbjct: 228 VKDKPVLSLKTSLIDMNDIEDDAYAEKDGCGMDSLNKKFS--SAVLGEGPNNGYF-DKLP 284
Query: 77 DEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVF 120
E++ I ++L DLCR A CK S+ DP+ + L ++ +
Sbjct: 285 YELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPY 328
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 38.9 bits (89), Expect = 0.020
Identities = 20/56 (35%), Positives = 31/56 (55%)
Query: 60 QDLSAAPAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRL 115
+DL+ + +LP E+ + IF YL ++L R A V K + +A D +LW RL
Sbjct: 104 RDLNEMNDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 159
>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
sapiens]
Length = 434
Score = 38.5 bits (88), Expect = 0.026
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFE-YTRPMMHPEPGK 133
LP VVL+IF YL D A+ VC+R++E+ + LW++ E+ + T P
Sbjct: 45 LPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWRKFEFELNQSATSSFKSTHPDL 104
Query: 134 FYQINPEEYEH 144
QI + + H
Sbjct: 105 IQQIIKKHFAH 115
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 38.1 bits (87), Expect = 0.034
Identities = 31/119 (26%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Query: 9 GAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSAAPAE 68
G +P +LR + L P + P S S S + R S + P +
Sbjct: 1000 GLNGTPRELRHQ-LGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLD 1058
Query: 69 QYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 127
+ EV + +FSYL QDLC VC+ ++ D LW R+ + + P+M
Sbjct: 1059 DGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLM 1117
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 38.1 bits (87), Expect = 0.034
Identities = 31/119 (26%), Positives = 48/119 (40%), Gaps = 1/119 (0%)
Query: 9 GAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSAAPAE 68
G +P +LR + L P + P S S S + R S + P +
Sbjct: 931 GLNGTPRELRHQ-LGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLD 989
Query: 69 QYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMM 127
+ EV + +FSYL QDLC VC+ ++ D LW R+ + + P+M
Sbjct: 990 DGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLM 1048
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,844,280
Number of Sequences: 37866
Number of extensions: 1684347
Number of successful extensions: 3508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3275
Number of HSP's gapped (non-prelim): 113
length of query: 843
length of database: 18,247,518
effective HSP length: 111
effective length of query: 732
effective length of database: 14,044,392
effective search space: 10280494944
effective search space used: 10280494944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.