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Search of human proteins with 30039710
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
(328 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 678 0.0
gi|23097242 nephew of atonal 3 [Homo sapiens] 79 4e-15
gi|4507741 twist [Homo sapiens] 75 6e-14
gi|17981708 twist homolog 2 [Homo sapiens] 72 7e-13
gi|31077092 neurogenin 2 [Homo sapiens] 72 9e-13
gi|38455396 neurogenin 1 [Homo sapiens] 70 3e-12
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 67 3e-11
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 66 4e-11
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens] 65 6e-11
gi|226498192 atonal homolog 8 [Homo sapiens] 64 2e-10
gi|4885075 atonal homolog 1 [Homo sapiens] 64 2e-10
gi|21553337 atonal homolog 7 [Homo sapiens] 64 2e-10
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 63 3e-10
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 63 4e-10
gi|5031943 nescient helix loop helix 1 [Homo sapiens] 63 4e-10
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9... 62 5e-10
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9... 62 5e-10
gi|116805332 musculin [Homo sapiens] 62 7e-10
gi|148922889 scleraxis homolog B [Homo sapiens] 62 9e-10
gi|186972126 scleraxis homolog A [Homo sapiens] 62 9e-10
gi|68989258 neurogenin 3 [Homo sapiens] 60 2e-09
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 60 2e-09
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens] 60 3e-09
gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph... 59 5e-09
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph... 59 5e-09
gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo sa... 59 5e-09
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 59 5e-09
gi|4505299 myogenic factor 6 [Homo sapiens] 59 8e-09
gi|206597481 achaete-scute complex-like 4 [Homo sapiens] 59 8e-09
gi|10190680 ASCL3 [Homo sapiens] 59 8e-09
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 678 bits (1750), Expect = 0.0
Identities = 328/328 (100%), Positives = 328/328 (100%)
Query: 1 MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEY 60
MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEY
Sbjct: 1 MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEY 60
Query: 61 CYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPS 120
CYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPS
Sbjct: 61 CYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPS 120
Query: 121 CLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSIN 180
CLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSIN
Sbjct: 121 CLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSIN 180
Query: 181 DAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG 240
DAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG
Sbjct: 181 DAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG 240
Query: 241 RLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKV 300
RLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKV
Sbjct: 241 RLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKV 300
Query: 301 WTPEDPRKLNSKSSFNNIENEPPFEFVS 328
WTPEDPRKLNSKSSFNNIENEPPFEFVS
Sbjct: 301 WTPEDPRKLNSKSSFNNIENEPPFEFVS 328
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 79.3 bits (194), Expect = 4e-15
Identities = 39/79 (49%), Positives = 60/79 (75%), Gaps = 4/79 (5%)
Query: 143 GAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKV 202
G + +R+RV + A+ RQAAN+RER+RM ++N+AF+ LR +PT YEKRLS++
Sbjct: 85 GVSLLGRPKRKRVITYAQ----RQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRI 140
Query: 203 DTLRLAIGYINFLSELVQA 221
+TLRLAI YI+F++EL+++
Sbjct: 141 ETLRLAIVYISFMTELLES 159
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 75.5 bits (184), Expect = 6e-14
Identities = 53/128 (41%), Positives = 68/128 (53%), Gaps = 8/128 (6%)
Query: 95 GGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRR 154
GGG G G GG PGSP S G G +G ++
Sbjct: 47 GGGAGPGGAAGGGVGGGD-EPGSPAQ------GKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
Query: 155 VRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINF 214
+S ELQ R ANVRER+R QS+N+AF LR IPTLP +K LSK+ TL+LA YI+F
Sbjct: 100 PQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDF 158
Query: 215 LSELVQAD 222
L +++Q+D
Sbjct: 159 LYQVLQSD 166
Score = 35.4 bits (80), Expect = 0.070
Identities = 16/25 (64%), Positives = 16/25 (64%)
Query: 228 GGAGGCGGPGGGGRLGGDSPGSQAQ 252
GG G GG GGG GGD PGS AQ
Sbjct: 47 GGGAGPGGAAGGGVGGGDEPGSPAQ 71
Score = 30.0 bits (66), Expect = 2.9
Identities = 13/23 (56%), Positives = 14/23 (60%)
Query: 226 RGGGAGGCGGPGGGGRLGGDSPG 248
RG + GCGG GG G GG S G
Sbjct: 74 RGKKSAGCGGGGGAGGGGGSSSG 96
Score = 28.9 bits (63), Expect = 6.6
Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 4/33 (12%)
Query: 227 GGGAGGCGGPGGGGRLGGDSPGS----QAQKVI 255
G G GG G GGG GG SP S Q Q+V+
Sbjct: 80 GCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVM 112
>gi|17981708 twist homolog 2 [Homo sapiens]
Length = 160
Score = 72.0 bits (175), Expect = 7e-13
Identities = 44/90 (48%), Positives = 58/90 (64%), Gaps = 9/90 (10%)
Query: 133 SPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPT 192
SP RG G+ +A +S ELQ R ANVRER+R QS+N+AF LR IPT
Sbjct: 44 SPTPGKRGKKGSPSA--------QSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPT 95
Query: 193 LPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
LP +K LSK+ TL+LA YI+FL +++Q+D
Sbjct: 96 LPSDK-LSKIQTLKLAARYIDFLYQVLQSD 124
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 71.6 bits (174), Expect = 9e-13
Identities = 78/264 (29%), Positives = 106/264 (40%), Gaps = 51/264 (19%)
Query: 52 FLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDD--GGGGGYCCETGAPPG 109
F+ + E + +LL A PA AL P SS E ++ G GG + GA G
Sbjct: 2 FVKSETLELKEEEDVLVLLGSASPALA-ALTPLSSSADEEEEEEPGASGGARRQRGAEAG 60
Query: 110 GFPYSPGSPPSCLAYPCAGAAVLSPGARLRGL-------SGAAAAAARRRRRVRSEAELQ 162
AGA P ARL GL A A +R + + ++
Sbjct: 61 ---------QGARGGVAAGAEGCRP-ARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIK 110
Query: 163 QLRQA-ANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQA 221
+ R+ AN RER RM ++N A + LR +PT P + +L+K++TLR A YI L+E ++
Sbjct: 111 KTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRL 170
Query: 222 DLPLRGGGAGGCG---------GPGGGGRL---GGDSP------------------GSQA 251
GGG G G PGG GDSP S +
Sbjct: 171 ADHCGGGGGGLPGALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNS 230
Query: 252 QKVIICHRGTRSPSPSDPDYGLPP 275
C SP+ SD DY PP
Sbjct: 231 TSPYSCTLSPASPAGSDMDYWQPP 254
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 70.1 bits (170), Expect = 3e-12
Identities = 47/110 (42%), Positives = 65/110 (59%), Gaps = 7/110 (6%)
Query: 128 GAAVLSPGARLRGLSGAAAAAARRR--RRVRSEAELQQLRQA----ANVRERRRMQSIND 181
GA +S + + G RRR RVRSEA L LR++ AN RER RM ++N
Sbjct: 51 GAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNA 110
Query: 182 AFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ-ADLPLRGGGA 230
A + LRS +P+ P + +L+K++TLR A YI L+E ++ AD L GGGA
Sbjct: 111 ALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGA 160
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 66.6 bits (161), Expect = 3e-11
Identities = 46/133 (34%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 105 GAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQL 164
G P G P P L A AA +PG R G + RR + Q
Sbjct: 24 GTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPGGRRDSSI-------QR 76
Query: 165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLP 224
R +N RER+RM +N+AF+ LR IP + +K+LSK++TL LA YI L+ + L
Sbjct: 77 RLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATI---LT 133
Query: 225 LRGGGAGGCGGPG 237
+ G GPG
Sbjct: 134 MSSSRLPGLEGPG 146
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 66.2 bits (160), Expect = 4e-11
Identities = 68/220 (30%), Positives = 93/220 (42%), Gaps = 22/220 (10%)
Query: 73 APPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYP---CAGA 129
+P L L S G G GG + PP G+ S A+P G+
Sbjct: 14 SPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGS 73
Query: 130 AVLSPGARLRG-LSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRS 188
S + S AAA++ ++ ++ +E ELQQLR N RER+RM +N A +GLR
Sbjct: 74 GFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLRE 133
Query: 189 HIPTL--PYEKRLSKVDTLRLAIGYI----NFLSELVQADLPLRGGGAGG-----CGGPG 237
+P P ++LSK+ TL LA YI N L E+ + + GG G CGG
Sbjct: 134 VMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLA 193
Query: 238 GGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLA 277
L P + A H P+ P LPP A
Sbjct: 194 HSAPL----PAATAHPAAAAH-AAHHPAVHHPI--LPPAA 226
>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
Length = 331
Score = 65.5 bits (158), Expect = 6e-11
Identities = 41/83 (49%), Positives = 50/83 (60%), Gaps = 12/83 (14%)
Query: 169 NVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGG 228
N RER R Q++N AF LR IPT P +K+LSK + LRLA+ YINFL++L+ D G
Sbjct: 193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLN-DQEEEGT 251
Query: 229 -----------GAGGCGGPGGGG 240
GAGG GG GGGG
Sbjct: 252 QRAKTGKDPVVGAGGGGGGGGGG 274
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/164 (30%), Positives = 76/164 (46%), Gaps = 13/164 (7%)
Query: 72 PAPPAAPLALAP--PSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCA-- 127
P PP AP + AP P + EP C P P +P +PP P
Sbjct: 126 PPPPPAPQSQAPGGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPT 185
Query: 128 --GAAVLSPGARLRGLSGAAAAAARRRR---RVRSEAELQQLRQA----ANVRERRRMQS 178
G + S + + + ++A+ R+R + +E++ L+Q AN RER R+ +
Sbjct: 186 RPGESSYSSISHVIYNNHQDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHT 245
Query: 179 INDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
I+ AFE LR +P Y ++LSK+ LR+A YI L+ L D
Sbjct: 246 ISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLARLADLD 289
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 63.5 bits (153), Expect = 2e-10
Identities = 33/59 (55%), Positives = 44/59 (74%)
Query: 162 QQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ 220
+Q R AAN RERRRM +N AF+ LR+ IP+ +K+LSK +TL++A YIN LSEL+Q
Sbjct: 158 KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQ 216
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 63.5 bits (153), Expect = 2e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query: 125 PCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFE 184
P AGA V P A +G A A R R R AAN RERRRMQ +N AF+
Sbjct: 9 PPAGARVAPPCAGGTECAGTCAGAGRLESAARR-------RLAANARERRRMQGLNTAFD 61
Query: 185 GLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 219
LR +P +K+LSK +TL++A+ YI L+ ++
Sbjct: 62 RLRRVVPQWGQDKKLSKYETLQMALSYIMALTRIL 96
>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
sapiens]
Length = 199
Score = 63.2 bits (152), Expect = 3e-10
Identities = 31/55 (56%), Positives = 41/55 (74%)
Query: 165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 219
RQAAN RER R QS+N AF LR+ IPT P +++LSK++TLRLA YI L+ ++
Sbjct: 74 RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVL 128
>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 203
Score = 62.8 bits (151), Expect = 4e-10
Identities = 69/192 (35%), Positives = 85/192 (44%), Gaps = 30/192 (15%)
Query: 105 GAPPGGFPYSPGSPPSC--LAYPCAGAAVLSPG--ARLRGLSGAAA--------AAARRR 152
GAP G G+ S L PC PG + + G +GA+ A RR
Sbjct: 4 GAPGLGLTARKGAEDSAEDLGGPCP-----EPGGDSGVLGANGASCSRGEAEEPAGRRRA 58
Query: 153 RRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYI 212
R VRS+A R AANVRER+R+ N+AF LR + KRLSK+ TLR AI I
Sbjct: 59 RPVRSKAR----RMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRI 114
Query: 213 NFLSELVQADLPLRGG-GAGGCGGPGGGGRLG--GDSPGSQAQKVIICHRGTRSPSPSD- 268
LS +++A RG G C GP G G G SP A + R PS
Sbjct: 115 AALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAP 174
Query: 269 -----PDYGLPP 275
P +G PP
Sbjct: 175 RCASCPPHGPPP 186
>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
Length = 133
Score = 62.8 bits (151), Expect = 4e-10
Identities = 49/130 (37%), Positives = 67/130 (51%), Gaps = 20/130 (15%)
Query: 90 GEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAA 149
G D GGG G GA PGG PG + G PG + L +
Sbjct: 22 GFSDCGGGAG---PDGAGPGG----PGGGQA------RGPEPGEPGRK--DLQHLSREER 66
Query: 150 RRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAI 209
RRRRR ++ R A RER R+++ N AF LR +PTLP +K+LSK++ LRLAI
Sbjct: 67 RRRRRATAK-----YRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAI 121
Query: 210 GYINFLSELV 219
YI++L+ ++
Sbjct: 122 CYISYLNHVL 131
Score = 28.5 bits (62), Expect = 8.6
Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 3/30 (10%)
Query: 227 GGGAGGCG-GPGG--GGRLGGDSPGSQAQK 253
GGGAG G GPGG GG+ G PG +K
Sbjct: 27 GGGAGPDGAGPGGPGGGQARGPEPGEPGRK 56
>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 62.4 bits (150), Expect = 5e-10
Identities = 66/180 (36%), Positives = 81/180 (45%), Gaps = 24/180 (13%)
Query: 105 GAPPGGFPYSPGSPPSC--LAYPCAGAAVLSPG--ARLRGLSGAAA--------AAARRR 152
GAP G G+ S L PC PG + + G +GA+ A RR
Sbjct: 4 GAPGLGLTARKGAEDSAEDLGGPCP-----EPGGDSGVLGANGASCSRGEAEEPAGRRRA 58
Query: 153 RRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYI 212
R VRS+A R AANVRER+R+ N+AF LR + KRLSK+ TLR AI I
Sbjct: 59 RPVRSKAR----RMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRI 114
Query: 213 NFLSELVQADLPLRGG-GAGGCGGPGGGGRLG--GDSPGSQAQKVIICHRGTRSPSPSDP 269
LS +++A RG G C GP G G G SP A + R PS P
Sbjct: 115 AALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAP 174
>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 62.4 bits (150), Expect = 5e-10
Identities = 66/180 (36%), Positives = 81/180 (45%), Gaps = 24/180 (13%)
Query: 105 GAPPGGFPYSPGSPPSC--LAYPCAGAAVLSPG--ARLRGLSGAAA--------AAARRR 152
GAP G G+ S L PC PG + + G +GA+ A RR
Sbjct: 4 GAPGLGLTARKGAEDSAEDLGGPCP-----EPGGDSGVLGANGASCSRGEAEEPAGRRRA 58
Query: 153 RRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYI 212
R VRS+A R AANVRER+R+ N+AF LR + KRLSK+ TLR AI I
Sbjct: 59 RPVRSKAR----RMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRI 114
Query: 213 NFLSELVQADLPLRGG-GAGGCGGPGGGGRLG--GDSPGSQAQKVIICHRGTRSPSPSDP 269
LS +++A RG G C GP G G G SP A + R PS P
Sbjct: 115 AALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAP 174
>gi|116805332 musculin [Homo sapiens]
Length = 206
Score = 62.0 bits (149), Expect = 7e-10
Identities = 51/158 (32%), Positives = 70/158 (44%), Gaps = 22/158 (13%)
Query: 72 PAPPAAPL-----ALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPC 126
PA PL + A PS E +D G C G + GS C
Sbjct: 24 PASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALG--------TAGSAEGCKR--- 72
Query: 127 AGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAE--LQQLRQAANVRERRRMQSINDAFE 184
V G G G+A ++ + A Q R AAN RER RM+ ++ AF
Sbjct: 73 KRPRVAGGG----GAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFS 128
Query: 185 GLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
L++ +P +P + +LSK+DTLRLA YI L +L+Q D
Sbjct: 129 RLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQED 166
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 61.6 bits (148), Expect = 9e-10
Identities = 45/106 (42%), Positives = 56/106 (52%), Gaps = 12/106 (11%)
Query: 140 GLSGAAAAAARRRRRV-----RSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLP 194
GL GA A RR R E +Q R AN RER R S+N AF LR+ IPT P
Sbjct: 48 GLQGARRRAGGRRAGGGGPGGRPGREPRQ-RHTANARERDRTNSVNTAFTALRTLIPTEP 106
Query: 195 YEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG 240
+++LSK++TLRLA YI+ L ++ A G A G G P G
Sbjct: 107 ADRKLSKIETLRLASSYISHLGNVLLA------GEACGDGQPCHSG 146
>gi|186972126 scleraxis homolog A [Homo sapiens]
Length = 201
Score = 61.6 bits (148), Expect = 9e-10
Identities = 45/106 (42%), Positives = 56/106 (52%), Gaps = 12/106 (11%)
Query: 140 GLSGAAAAAARRRRRV-----RSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLP 194
GL GA A RR R E +Q R AN RER R S+N AF LR+ IPT P
Sbjct: 48 GLQGARRRAGGRRAGGGGPGGRPGREPRQ-RHTANARERDRTNSVNTAFTALRTLIPTEP 106
Query: 195 YEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGG 240
+++LSK++TLRLA YI+ L ++ A G A G G P G
Sbjct: 107 ADRKLSKIETLRLASSYISHLGNVLLA------GEACGDGQPCHSG 146
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 60.5 bits (145), Expect = 2e-09
Identities = 55/174 (31%), Positives = 77/174 (44%), Gaps = 25/174 (14%)
Query: 102 CETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAEL 161
C T APP P+ CA A R L +R + + +
Sbjct: 31 CPTSAPPS---------PTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQR 81
Query: 162 QQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ- 220
+ R+ AN RER RM ++N A + LR +PT P + +L+K++TLR A YI L++ ++
Sbjct: 82 RSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRI 141
Query: 221 ADLPLRG--GGAGGCGGPGGGGRLGGD-----SPGSQAQKVIICHRGTRSPSPS 267
AD L A CG G G GD SP SQA G+ SP+ S
Sbjct: 142 ADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQA--------GSLSPAAS 187
>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
sapiens]
Length = 217
Score = 60.5 bits (145), Expect = 2e-09
Identities = 31/58 (53%), Positives = 39/58 (67%)
Query: 165 RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
R AN +ERRR QSIN AF LR IP +P + +LSK+ TLRLA YI +L +L+ D
Sbjct: 101 RGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKD 158
>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
Length = 108
Score = 60.1 bits (144), Expect = 3e-09
Identities = 41/99 (41%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
Query: 169 NVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGG 228
N RER R Q++N AF LR IPT P +K+LSK +TLRLA+ YINFL + V + L+
Sbjct: 8 NTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVK-VLGEQSLQQT 66
Query: 229 GAGGCGGPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPS 267
G G G G PG + + ++ + SP PS
Sbjct: 67 GVAAQGNILGLFPQGPHLPGLE-DRTLLENYQVPSPGPS 104
>gi|239752994 PREDICTED: achaete-scute complex homolog 5
(Drosophila) [Homo sapiens]
Length = 313
Score = 59.3 bits (142), Expect = 5e-09
Identities = 38/90 (42%), Positives = 49/90 (54%), Gaps = 9/90 (10%)
Query: 166 QAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ----- 220
Q N RER+R++ +N+ + LR H+P EKRLSKV+TLR AI YI +L EL+
Sbjct: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDG 252
Query: 221 ADLPLRGG--GAGGCGGPGGGGRLGGDSPG 248
+ P G G G C P R D PG
Sbjct: 253 STPPASRGLPGTGPCPAPPATPR--PDRPG 280
>gi|239747548 PREDICTED: achaete-scute complex homolog 5
(Drosophila) [Homo sapiens]
Length = 313
Score = 59.3 bits (142), Expect = 5e-09
Identities = 38/90 (42%), Positives = 49/90 (54%), Gaps = 9/90 (10%)
Query: 166 QAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ----- 220
Q N RER+R++ +N+ + LR H+P EKRLSKV+TLR AI YI +L EL+
Sbjct: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDG 252
Query: 221 ADLPLRGG--GAGGCGGPGGGGRLGGDSPG 248
+ P G G G C P R D PG
Sbjct: 253 STPPASRGLPGTGPCPAPPATPR--PDRPG 280
>gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo
sapiens]
Length = 313
Score = 59.3 bits (142), Expect = 5e-09
Identities = 38/90 (42%), Positives = 49/90 (54%), Gaps = 9/90 (10%)
Query: 166 QAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ----- 220
Q N RER+R++ +N+ + LR H+P EKRLSKV+TLR AI YI +L EL+
Sbjct: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDG 252
Query: 221 ADLPLRGG--GAGGCGGPGGGGRLGGDSPG 248
+ P G G G C P R D PG
Sbjct: 253 STPPASRGLPGTGPCPAPPATPR--PDRPG 280
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 59.3 bits (142), Expect = 5e-09
Identities = 52/141 (36%), Positives = 64/141 (45%), Gaps = 19/141 (13%)
Query: 80 ALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAA------VLS 133
A A + G EP+ G G T P G P +P A +G
Sbjct: 22 AAAGLAYGAAREPEAARGYG----TPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFE 77
Query: 134 PGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTL 193
R RG G+AA RR R RS LR + N RERRRM +NDA +GLR+ IP
Sbjct: 78 QRRRRRG-PGSAADGRRRPREQRS------LRLSINARERRRMHDLNDALDGLRAVIPYA 130
Query: 194 --PYEKRLSKVDTLRLAIGYI 212
P ++LSK+ TL LA YI
Sbjct: 131 HSPSVRKLSKIATLLLAKNYI 151
>gi|4505299 myogenic factor 6 [Homo sapiens]
Length = 242
Score = 58.5 bits (140), Expect = 8e-09
Identities = 51/166 (30%), Positives = 69/166 (41%), Gaps = 35/166 (21%)
Query: 60 YCYRDGACLLLQPAPPAAPLALAPPSSGGLGE------PDDGGGGGYCCETGAPPGGFPY 113
+ Y DG + LQP A L P S G L P+ G APPG P
Sbjct: 12 FFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQP- 70
Query: 114 SPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRER 173
P P CL + C + + ++ R+AA +RER
Sbjct: 71 -PHCPGQCLIWAC--------------------------KTCKRKSAPTDRRKAATLRER 103
Query: 174 RRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELV 219
RR++ IN+AFE L+ P +RL KV+ LR AI YI L +L+
Sbjct: 104 RRLKKINEAFEALKRRTVANP-NQRLPKVEILRSAISYIERLQDLL 148
>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
Length = 173
Score = 58.5 bits (140), Expect = 8e-09
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 7/92 (7%)
Query: 169 NVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGG 228
N RER+R++ +N+ + LR H+P +KRLSKV+TLR AI YI L EL++ G
Sbjct: 79 NERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEG 138
Query: 229 GAGG-------CGGPGGGGRLGGDSPGSQAQK 253
AG C G SP S+ ++
Sbjct: 139 AAGAVPQRRAECNSDGESKASSAPSPSSEPEE 170
>gi|10190680 ASCL3 [Homo sapiens]
Length = 181
Score = 58.5 bits (140), Expect = 8e-09
Identities = 28/54 (51%), Positives = 38/54 (70%)
Query: 169 NVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD 222
N RER+R++ +N+ + LR H+P EKRLSKV+TLR AI YIN+L L+ D
Sbjct: 99 NERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPD 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.137 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,609,305
Number of Sequences: 37866
Number of extensions: 1017991
Number of successful extensions: 10425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 253
Number of HSP's successfully gapped in prelim test: 349
Number of HSP's that attempted gapping in prelim test: 6676
Number of HSP's gapped (non-prelim): 3125
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.