BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo sapiens] (255 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo sap... 531 e-151 gi|4503095 casein kinase II alpha 1 subunit isoform a [Homo sapi... 531 e-151 gi|29570791 casein kinase II alpha 1 subunit isoform a [Homo sap... 531 e-151 gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens] 374 e-104 gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] 120 9e-28 gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 117 7e-27 gi|225903437 glycogen synthase kinase 3 beta isoform 2 [Homo sap... 115 5e-26 gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] 114 8e-26 gi|21361340 glycogen synthase kinase 3 beta isoform 1 [Homo sapi... 114 1e-25 gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] 113 2e-25 gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 110 2e-24 gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] 110 2e-24 gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 109 2e-24 gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ... 108 5e-24 gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 108 5e-24 gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 108 6e-24 gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s... 107 1e-23 gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s... 107 1e-23 gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s... 105 3e-23 gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 105 4e-23 gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] 104 9e-23 gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] 104 9e-23 gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 103 1e-22 gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] 103 1e-22 gi|27477122 intestinal cell kinase [Homo sapiens] 101 6e-22 gi|7662388 intestinal cell kinase [Homo sapiens] 101 6e-22 gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 99 3e-21 gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 99 3e-21 gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] 99 4e-21 gi|11496279 male germ cell-associated kinase [Homo sapiens] 99 5e-21 >gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo sapiens] Length = 255 Score = 531 bits (1367), Expect = e-151 Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY Sbjct: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD Sbjct: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR Sbjct: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA Sbjct: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240 Query: 241 NPLGMPVPAAAGAQQ 255 NPLGMPVPAAAGAQQ Sbjct: 241 NPLGMPVPAAAGAQQ 255 >gi|4503095 casein kinase II alpha 1 subunit isoform a [Homo sapiens] Length = 391 Score = 531 bits (1367), Expect = e-151 Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY Sbjct: 137 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 196 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD Sbjct: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR Sbjct: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316 Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA Sbjct: 317 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 376 Query: 241 NPLGMPVPAAAGAQQ 255 NPLGMPVPAAAGAQQ Sbjct: 377 NPLGMPVPAAAGAQQ 391 >gi|29570791 casein kinase II alpha 1 subunit isoform a [Homo sapiens] Length = 391 Score = 531 bits (1367), Expect = e-151 Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY Sbjct: 137 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 196 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD Sbjct: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR Sbjct: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316 Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA Sbjct: 317 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 376 Query: 241 NPLGMPVPAAAGAQQ 255 NPLGMPVPAAAGAQQ Sbjct: 377 NPLGMPVPAAAGAQQ 391 >gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens] Length = 350 Score = 374 bits (960), Expect = e-104 Identities = 171/197 (86%), Positives = 186/197 (94%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MYE+LKALDYCHS GIMHRDVKPHNVMIDH+ +KLRLIDWGLAEFYHP QEYNVRVASRY Sbjct: 138 MYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRY 197 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFR+EPFFHG DNYDQLVRIAKVLGTE+LY Sbjct: 198 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYG 257 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 Y+ KY+I+LDP FNDILG+HSRKRWE F+HSEN+HLVSPEALD LDKLLRYDHQ RLTA+ Sbjct: 258 YLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAK 317 Query: 181 EAMEHPYFYTVVKDQAR 197 EAMEHPYFY VVK+Q++ Sbjct: 318 EAMEHPYFYPVVKEQSQ 334 >gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens] Length = 365 Score = 120 bits (302), Expect = 9e-28 Identities = 66/188 (35%), Positives = 111/188 (59%), Gaps = 10/188 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 +Y++LK L Y HS G++HRD+KP N+ ++ E +L+++D+GLA H E V +R+ Sbjct: 131 VYQMLKGLKYIHSAGVVHRDLKPGNLAVN-EDCELKILDFGLAR--HADAEMTGYVVTRW 187 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+++ + Y+ ++D+WS+GC++A M+ K F G D DQL +I KV G + Sbjct: 188 YRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGK-TLFKGKDYLDQLTQILKVTGVPGT-E 245 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 ++ K N + + L + RK + + SP+A D L+K+L D RLTA Sbjct: 246 FVQKLNDKAAKSYIQSLPQTPRKDFTQLFPR-----ASPQAADLLEKMLELDVDKRLTAA 300 Query: 181 EAMEHPYF 188 +A+ HP+F Sbjct: 301 QALTHPFF 308 >gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] Length = 305 Score = 117 bits (294), Expect = 7e-27 Identities = 67/191 (35%), Positives = 112/191 (58%), Gaps = 15/191 (7%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 ++++L+ + +CHS ++HRD+KP N++I+ E ++L D+GLA F P + Y V + Sbjct: 108 LFQLLQGVSFCHSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTL 166 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT--ED 117 +++ PE+L+ + Y ++D+WS+GC+ A M+ RK F G DQL RI ++LGT ED Sbjct: 167 WYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRK-ALFPGDSEIDQLFRIFRMLGTPSED 225 Query: 118 LYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRL 177 + + + P + + +RK E V + + PE D L +LL+YD R+ Sbjct: 226 TWPGVTQL-----PDYKGSFPKWTRKGLEEIVPN-----LEPEGRDLLMQLLQYDPSQRI 275 Query: 178 TAREAMEHPYF 188 TA+ A+ HPYF Sbjct: 276 TAKTALAHPYF 286 >gi|225903437 glycogen synthase kinase 3 beta isoform 2 [Homo sapiens] Length = 420 Score = 115 bits (287), Expect = 5e-26 Identities = 77/250 (30%), Positives = 120/250 (48%), Gaps = 25/250 (10%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY++ ++L Y HS GI HRD+KP N+++D + L+L D+G A+ G+ + SRY Sbjct: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 221 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PEL+ Y S+D+WS GC+LA ++ +P F G DQLV I KVLGT Sbjct: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTP---- 276 Query: 121 YIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179 + E++P + + + W + PEA+ +LL Y +RLT Sbjct: 277 -TREQIREMNPNYTEFKFPQIKAHPWTKVFRPR----TPPEAIALCSRLLEYTPTARLTP 331 Query: 180 REAMEHPYFYTVVKDQARMGSSSMPGG---------STPVSSANMMSGISSVPTPSPLGP 230 EA H +F D+ R + +P G +T S+N +P + + Sbjct: 332 LEACAHSFF-----DELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQA 386 Query: 231 LAGSPVIAAA 240 A +P A A Sbjct: 387 AASTPTNATA 396 >gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] Length = 483 Score = 114 bits (285), Expect = 8e-26 Identities = 71/223 (31%), Positives = 110/223 (49%), Gaps = 16/223 (7%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY++ ++L Y HS G+ HRD+KP N+++D + L+L D+G A+ G+ + SRY Sbjct: 225 MYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 284 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PEL+ Y S+D+WS GC+LA ++ +P F G DQLV I KVLGT Sbjct: 285 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTP---- 339 Query: 121 YIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179 + E++P + + + W + S PEA+ LL Y SRL+ Sbjct: 340 -TREQIREMNPNYTEFKFPQIKAHPWTKVFKSR----TPPEAIALCSSLLEYTPSSRLSP 394 Query: 180 REAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSV 222 EA H +F D+ R + +P N +G S+ Sbjct: 395 LEACAHSFF-----DELRCLGTQLPNNRPLPPLFNFSAGELSI 432 >gi|21361340 glycogen synthase kinase 3 beta isoform 1 [Homo sapiens] Length = 433 Score = 114 bits (284), Expect = 1e-25 Identities = 81/258 (31%), Positives = 120/258 (46%), Gaps = 28/258 (10%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY++ ++L Y HS GI HRD+KP N+++D + L+L D+G A+ G+ + SRY Sbjct: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 221 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---ED 117 ++ PEL+ Y S+D+WS GC+LA ++ +P F G DQLV I KVLGT E Sbjct: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTPTREQ 280 Query: 118 LYDYIDKY------NIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171 + + Y I+ P D G R PEA+ +LL Y Sbjct: 281 IREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPR----TPPEAIALCSRLLEY 336 Query: 172 DHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGG---------STPVSSANMMSGISSV 222 +RLT EA H +F D+ R + +P G +T S+N + Sbjct: 337 TPTARLTPLEACAHSFF-----DELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILI 391 Query: 223 PTPSPLGPLAGSPVIAAA 240 P + + A +P A A Sbjct: 392 PPHARIQAAASTPTNATA 409 >gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens] Length = 367 Score = 113 bits (282), Expect = 2e-25 Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 10/188 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 +Y++LK L Y H+ GI+HRD+KP N+ ++ E +L+++D+GLA E V +R+ Sbjct: 134 VYQMLKGLRYIHAAGIIHRDLKPGNLAVN-EDCELKILDFGLAR--QADSEMTGYVVTRW 190 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+++++ Y ++D+WS+GC++A MI K F G D+ DQL I KV GT + Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK-TLFKGSDHLDQLKEIMKVTGTPPA-E 248 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 ++ + + + L +K + + + SP A++ L+K+L D + R+TA Sbjct: 249 FVQRLQSDEAKNYMKGLPELEKKDFASILTN-----ASPLAVNLLEKMLVLDAEQRVTAG 303 Query: 181 EAMEHPYF 188 EA+ HPYF Sbjct: 304 EALAHPYF 311 >gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] Length = 297 Score = 110 bits (274), Expect = 2e-24 Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 13/190 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 +Y+IL+ + +CHS ++HRD+KP N++ID + ++L D+GLA F P + Y V + Sbjct: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTL 167 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119 +++ PE+L+ Y +D+WS+G + A + K+P FHG DQL RI + LGT Sbjct: 168 WYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKKPLFHGDSEIDQLFRIFRALGTP--- 223 Query: 120 DYIDKYNIELDPRFNDILG-RHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178 N E+ P + +++ +W+ + + + LD L K+L YD R++ Sbjct: 224 ------NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277 Query: 179 AREAMEHPYF 188 + A+ HPYF Sbjct: 278 GKMALNHPYF 287 >gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens] Length = 364 Score = 110 bits (274), Expect = 2e-24 Identities = 64/188 (34%), Positives = 110/188 (58%), Gaps = 10/188 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 +Y++L+ L Y HS GI+HRD+KP NV ++ E +LR++D+GLA +E VA+R+ Sbjct: 131 VYQLLRGLKYIHSAGIIHRDLKPSNVAVN-EDCELRILDFGLAR--QADEEMTGYVATRW 187 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+++++ Y+ ++D+WS+GC++A ++ + + F G D DQL RI +V+GT + Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELL-QGKALFPGSDYIDQLKRIMEVVGTPS-PE 245 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 + K + E + L +K N P A+D L ++L D R++A Sbjct: 246 VLAKISSEHARTYIQSLPPMPQKDLSSIFRGAN-----PLAIDLLGRMLVLDSDQRVSAA 300 Query: 181 EAMEHPYF 188 EA+ H YF Sbjct: 301 EALAHAYF 308 >gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] Length = 298 Score = 109 bits (273), Expect = 2e-24 Identities = 63/195 (32%), Positives = 108/195 (55%), Gaps = 13/195 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 ++++L+ L +CHS ++HRD+KP N++I+ E ++L D+GLA F P + Y V + Sbjct: 108 LFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTL 166 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119 +++ PE+L+ + Y ++D+WSLGC+ A M+ R+ F G DQL RI + LGT D Sbjct: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRR-ALFPGDSEIDQLFRIFRTLGTPDEV 225 Query: 120 DYIDKYNI-ELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178 + ++ + P F +W R S+ + + L ++L YD R++ Sbjct: 226 VWPGVTSMPDYKPSF---------PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRIS 276 Query: 179 AREAMEHPYFYTVVK 193 A+ A+ HP+F V K Sbjct: 277 AKAALAHPFFQDVTK 291 >gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo sapiens] Length = 360 Score = 108 bits (270), Expect = 5e-24 Identities = 61/188 (32%), Positives = 110/188 (58%), Gaps = 10/188 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 +Y+IL+ L Y HS I+HRD+KP N+ ++ E +L+++D+GLA H E VA+R+ Sbjct: 131 IYQILRGLKYIHSADIIHRDLKPSNLAVN-EDCELKILDFGLAR--HTDDEMTGYVATRW 187 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+++++ Y+ ++D+WS+GC++A ++ + F G D+ DQL I +++GT + Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR-TLFPGTDHIDQLKLILRLVGTPGA-E 245 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 + K + E + L + + + N P A+D L+K+L D R+TA Sbjct: 246 LLKKISSESARNYIQSLTQMPKMNFANVFIGAN-----PLAVDLLEKMLVLDSDKRITAA 300 Query: 181 EAMEHPYF 188 +A+ H YF Sbjct: 301 QALAHAYF 308 >gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] Length = 346 Score = 108 bits (270), Expect = 5e-24 Identities = 63/189 (33%), Positives = 107/189 (56%), Gaps = 11/189 (5%) Query: 4 ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHP--GQEYNVRVASRYF 61 +LK + +CH+ I+HRD+KP N++I + L++ D+GLA + P + Y +VA+R++ Sbjct: 111 LLKGVAFCHANNIVHRDLKPANLLISASGQ-LKIADFGLARVFSPDGSRLYTHQVATRWY 169 Query: 62 KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDY 121 + PELL + YD +D+WS+GC++ ++ P F G ++ +QL + ++LGT + + Sbjct: 170 RAPELLYGARQYDQGVDLWSVGCIMGELL-NGSPLFPGKNDIEQLCYVLRILGTPNPQVW 228 Query: 122 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 181 + + P +N I S K E VSP+ALD L + L Y R+ A + Sbjct: 229 PELTEL---PDYNKI----SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASK 281 Query: 182 AMEHPYFYT 190 A+ H YF+T Sbjct: 282 ALLHQYFFT 290 >gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] Length = 297 Score = 108 bits (269), Expect = 6e-24 Identities = 61/190 (32%), Positives = 104/190 (54%), Gaps = 13/190 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 +Y+IL+ + +CHS ++HRD+KP N++ID + ++L D+GLA F P + Y + Sbjct: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEAITL 167 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119 +++ PE+L+ Y +D+WS+G + A + K+P FHG DQL RI + LGT Sbjct: 168 WYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKKPLFHGDSEIDQLFRIFRALGTP--- 223 Query: 120 DYIDKYNIELDPRFNDILG-RHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178 N E+ P + +++ +W+ + + + LD L K+L YD R++ Sbjct: 224 ------NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277 Query: 179 AREAMEHPYF 188 + A+ HPYF Sbjct: 278 GKMALNHPYF 287 >gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo sapiens] Length = 357 Score = 107 bits (267), Expect = 1e-23 Identities = 63/205 (30%), Positives = 109/205 (53%), Gaps = 12/205 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56 +Y+IL+ L Y HS ++HRD+KP N++I+ L++ D+GLA P ++ V Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTTC-DLKICDFGLARIADPEHDHTGFLTEYV 205 Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116 A+R+++ PE++++ + Y S+D+WS+GC+LA M+ + P F G DQL I +LG+ Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 264 Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176 D N++ + L ++ W + + +ALD LD++L ++ R Sbjct: 265 SQEDLNCIINMKA-RNYLQSLPSKTKVAWAKLFPKSDS-----KALDLLDRMLTFNPNKR 318 Query: 177 LTAREAMEHPYFYTVVKDQARMGSS 201 +T EA+ HPY +G S Sbjct: 319 ITVEEALAHPYLEQYYDPTDEVGQS 343 >gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo sapiens] Length = 379 Score = 107 bits (266), Expect = 1e-23 Identities = 61/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56 +Y+IL+ L Y HS ++HRD+KP N++I+ L++ D+GLA P ++ V Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTTC-DLKICDFGLARIADPEHDHTGFLTEYV 205 Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116 A+R+++ PE++++ + Y S+D+WS+GC+LA M+ + P F G DQL I +LG+ Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 264 Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176 D N++ + L ++ W + + +ALD LD++L ++ R Sbjct: 265 SQEDLNCIINMKA-RNYLQSLPSKTKVAWAKLFPKSDS-----KALDLLDRMLTFNPNKR 318 Query: 177 LTAREAMEHPY 187 +T EA+ HPY Sbjct: 319 ITVEEALAHPY 329 >gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo sapiens] Length = 360 Score = 105 bits (263), Expect = 3e-23 Identities = 60/188 (31%), Positives = 109/188 (57%), Gaps = 10/188 (5%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 +Y+IL+ L Y HS I+HRD+KP N+ ++ E +L+++D+GLA H E VA+R+ Sbjct: 131 IYQILRGLKYIHSADIIHRDLKPSNLAVN-EDCELKILDFGLAR--HTDDEMTGYVATRW 187 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+++++ Y+ ++D+WS+GC++A ++ + F G D+ +QL +I ++ GT Y Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR-TLFPGTDHINQLQQIMRLTGTPPAY- 245 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180 I++ + L + + + N P A+D L+K+L D R+TA Sbjct: 246 LINRMPSHEARNYIQSLTQMPKMNFANVFIGAN-----PLAVDLLEKMLVLDSDKRITAA 300 Query: 181 EAMEHPYF 188 +A+ H YF Sbjct: 301 QALAHAYF 308 >gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] Length = 292 Score = 105 bits (262), Expect = 4e-23 Identities = 61/193 (31%), Positives = 107/193 (55%), Gaps = 18/193 (9%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 ++++LK L +CHS ++HRD+KP N++I+ + +L+L D+GLA F P + Y+ V + Sbjct: 107 LFQLLKGLGFCHSRNVLHRDLKPQNLLINR-NGELKLADFGLARAFGIPVRCYSAEVVTL 165 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119 +++ P++L ++Y S+DMWS GC+ A + P F G+D DQL RI ++LGT Sbjct: 166 WYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGT---- 221 Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE----ALDFLDKLLRYDHQS 175 + ++ + K + + + + V P+ D L LL+ + Sbjct: 222 --------PTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQ 273 Query: 176 RLTAREAMEHPYF 188 R++A EA++HPYF Sbjct: 274 RISAEEALQHPYF 286 >gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens] Length = 360 Score = 104 bits (259), Expect = 9e-23 Identities = 60/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56 +Y+IL+ L Y HS ++HRD+KP N++++ L++ D+GLA P ++ V Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTC-DLKICDFGLARVADPDHDHTGFLTEYV 188 Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116 A+R+++ PE++++ + Y S+D+WS+GC+LA M+ + P F G DQL I +LG+ Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 247 Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176 D N++ + L ++ W R + + +ALD LDK+L ++ R Sbjct: 248 SQEDLNCIINLKA-RNYLLSLPHKNKVPWNRLFPNADS-----KALDLLDKMLTFNPHKR 301 Query: 177 LTAREAMEHPY 187 + +A+ HPY Sbjct: 302 IEVEQALAHPY 312 >gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens] Length = 360 Score = 104 bits (259), Expect = 9e-23 Identities = 60/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56 +Y+IL+ L Y HS ++HRD+KP N++++ L++ D+GLA P ++ V Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTC-DLKICDFGLARVADPDHDHTGFLTEYV 188 Query: 57 ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116 A+R+++ PE++++ + Y S+D+WS+GC+LA M+ + P F G DQL I +LG+ Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 247 Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176 D N++ + L ++ W R + + +ALD LDK+L ++ R Sbjct: 248 SQEDLNCIINLKA-RNYLLSLPHKNKVPWNRLFPNADS-----KALDLLDKMLTFNPHKR 301 Query: 177 LTAREAMEHPY 187 + +A+ HPY Sbjct: 302 IEVEQALAHPY 312 >gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] Length = 346 Score = 103 bits (258), Expect = 1e-22 Identities = 63/192 (32%), Positives = 106/192 (55%), Gaps = 18/192 (9%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59 M L+ L+Y H I+HRD+KP+N+++D E+ L+L D+GLA+ F P + Y +V +R Sbjct: 118 MLMTLQGLEYLHQHWILHRDLKPNNLLLD-ENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176 Query: 60 YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119 +++ PELL +MY +DMW++GC+LA ++ R PF G + DQL RI + LGT Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLR-VPFLPGDSDLDQLTRIFETLGT---- 231 Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS---PEALDFLDKLLRYDHQSR 176 + ++ D+ ++ F H+ S + LD + L ++ +R Sbjct: 232 --------PTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCAR 283 Query: 177 LTAREAMEHPYF 188 +TA +A++ YF Sbjct: 284 ITATQALKMKYF 295 >gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] Length = 419 Score = 103 bits (257), Expect = 1e-22 Identities = 65/212 (30%), Positives = 105/212 (49%), Gaps = 24/212 (11%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY++ K+LD+ H GI HRDVKP N++I + L+L D+G + Q Y +++R+ Sbjct: 109 MYQLCKSLDHIHRNGIFHRDVKPENILIKQD--VLKLGDFGSCRSVYSKQPYTEYISTRW 166 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE L+ Y Y +D+WS GC+ I +P F G + DQ+ +I V+GT Sbjct: 167 YRAPECLLTDGFYTYKMDLWSAGCVFYE-IASLQPLFPGVNELDQISKIHDVIGTP-AQK 224 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHL------VSPEALDFLDKLLRYDHQ 174 + K+ + SR F + + +SP+ L L ++ YD Sbjct: 225 ILTKF-------------KQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPD 271 Query: 175 SRLTAREAMEHPYFYTVVKDQAR-MGSSSMPG 205 R+ A +A++HPYF K + R +GS G Sbjct: 272 ERIAAHQALQHPYFQEQRKTEKRALGSHRKAG 303 >gi|27477122 intestinal cell kinase [Homo sapiens] Length = 632 Score = 101 bits (252), Expect = 6e-22 Identities = 58/191 (30%), Positives = 101/191 (52%), Gaps = 15/191 (7%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY+IL+ L + H G HRD+KP N++ +++ D+GLA Y V++R+ Sbjct: 106 MYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRW 164 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+L+ Y +D+W++GC++A ++ P F G D + +I +VLGT D Sbjct: 165 YRAPEVLLRSTNYSSPIDVWAVGCIMAE-VYTLRPLFPGASEIDTIFKICQVLGTPKKTD 223 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177 + + Y + F RW + V + + L+ S EA+ L +L++D + R Sbjct: 224 WPEGYQLSSAMNF----------RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273 Query: 178 TAREAMEHPYF 188 TA +A+ +PYF Sbjct: 274 TASQALRYPYF 284 >gi|7662388 intestinal cell kinase [Homo sapiens] Length = 632 Score = 101 bits (252), Expect = 6e-22 Identities = 58/191 (30%), Positives = 101/191 (52%), Gaps = 15/191 (7%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY+IL+ L + H G HRD+KP N++ +++ D+GLA Y V++R+ Sbjct: 106 MYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRW 164 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+L+ Y +D+W++GC++A ++ P F G D + +I +VLGT D Sbjct: 165 YRAPEVLLRSTNYSSPIDVWAVGCIMAE-VYTLRPLFPGASEIDTIFKICQVLGTPKKTD 223 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177 + + Y + F RW + V + + L+ S EA+ L +L++D + R Sbjct: 224 WPEGYQLSSAMNF----------RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273 Query: 178 TAREAMEHPYF 188 TA +A+ +PYF Sbjct: 274 TASQALRYPYF 284 >gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] Length = 1030 Score = 99.4 bits (246), Expect = 3e-21 Identities = 66/195 (33%), Positives = 100/195 (51%), Gaps = 16/195 (8%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ--EYNVRVAS 58 +Y+++KA+ +CH I+HRD+KP N++I H + L+L D+G A G Y VA+ Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISH-NDVLKLCDFGFARNLSEGNNANYTEYVAT 174 Query: 59 RYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDL 118 R+++ PELL+ Y S+DMWS+GC+L + +P F G DQL I KVLG Sbjct: 175 RWYRSPELLLG-APYGKSVDMWSVGCILGE-LSDGQPLFPGESEIDQLFTIQKVLGPLPS 232 Query: 119 YDYIDKYNIELDPRFNDI---LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175 Y+ +PRF+ + H + R++ N L LD + LL+ D Sbjct: 233 EQMKLFYS---NPRFHGLRFPAVNHPQSLERRYLGILNSVL-----LDLMKNLLKLDPAD 284 Query: 176 RLTAREAMEHPYFYT 190 R + + HP F T Sbjct: 285 RYLTEQCLNHPTFQT 299 >gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] Length = 1030 Score = 99.4 bits (246), Expect = 3e-21 Identities = 66/195 (33%), Positives = 100/195 (51%), Gaps = 16/195 (8%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ--EYNVRVAS 58 +Y+++KA+ +CH I+HRD+KP N++I H + L+L D+G A G Y VA+ Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISH-NDVLKLCDFGFARNLSEGNNANYTEYVAT 174 Query: 59 RYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDL 118 R+++ PELL+ Y S+DMWS+GC+L + +P F G DQL I KVLG Sbjct: 175 RWYRSPELLLG-APYGKSVDMWSVGCILGE-LSDGQPLFPGESEIDQLFTIQKVLGPLPS 232 Query: 119 YDYIDKYNIELDPRFNDI---LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175 Y+ +PRF+ + H + R++ N L LD + LL+ D Sbjct: 233 EQMKLFYS---NPRFHGLRFPAVNHPQSLERRYLGILNSVL-----LDLMKNLLKLDPAD 284 Query: 176 RLTAREAMEHPYFYT 190 R + + HP F T Sbjct: 285 RYLTEQCLNHPTFQT 299 >gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens] Length = 721 Score = 99.0 bits (245), Expect = 4e-21 Identities = 59/193 (30%), Positives = 101/193 (52%), Gaps = 16/193 (8%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVA--- 57 MY++L+ L Y HS ++HRD+KP N+ I+ E L++ D+GLA P + ++ Sbjct: 133 MYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGL 192 Query: 58 -SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGH--DNYDQLVRIAKVLG 114 +++++ P LL+ Y ++DMW+ GC+ A M+ K F H + ++ V+ Sbjct: 193 VTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVH 252 Query: 115 TEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQ 174 ED + + + + ND+ H K + + +S EALDFL+++L + Sbjct: 253 EEDRQELLSVIPVYIR---NDMTEPH--KPLTQLLPG-----ISREALDFLEQILTFSPM 302 Query: 175 SRLTAREAMEHPY 187 RLTA EA+ HPY Sbjct: 303 DRLTAEEALSHPY 315 >gi|11496279 male germ cell-associated kinase [Homo sapiens] Length = 623 Score = 98.6 bits (244), Expect = 5e-21 Identities = 64/242 (26%), Positives = 118/242 (48%), Gaps = 19/242 (7%) Query: 1 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60 MY+IL+ L + H G HRD+KP N++ +++ D+GLA Y V++R+ Sbjct: 106 MYQILQGLAFIHKHGFFHRDMKPENLLCMGPEL-VKIADFGLARELRSQPPYTDYVSTRW 164 Query: 61 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120 ++ PE+L+ +Y +D+W++G ++A ++ P F G D++ +I +VLGT D Sbjct: 165 YRAPEVLLRSSVYSSPIDVWAVGSIMAE-LYMLRPLFPGTSEVDEIFKICQVLGTPKKSD 223 Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177 + + Y + F R+ + V + L+ S EA+ + ++L +D + R Sbjct: 224 WPEGYQLASSMNF----------RFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRP 273 Query: 178 TAREAMEHPYFYT--VVKDQAR--MGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAG 233 TA +A++HPYF V+ + S+ P+ S + + P P + + G Sbjct: 274 TASQALKHPYFQVGQVLGPSSNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVG 333 Query: 234 SP 235 P Sbjct: 334 QP 335 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,572,503 Number of Sequences: 37866 Number of extensions: 505027 Number of successful extensions: 4098 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 559 Number of HSP's successfully gapped in prelim test: 232 Number of HSP's that attempted gapping in prelim test: 2580 Number of HSP's gapped (non-prelim): 1112 length of query: 255 length of database: 18,247,518 effective HSP length: 100 effective length of query: 155 effective length of database: 14,460,918 effective search space: 2241442290 effective search space used: 2241442290 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.