Guide to the Human Genome
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Search of human proteins with 29570793

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo
sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo sap...   531   e-151
gi|4503095 casein kinase II alpha 1 subunit isoform a [Homo sapi...   531   e-151
gi|29570791 casein kinase II alpha 1 subunit isoform a [Homo sap...   531   e-151
gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens]    374   e-104
gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]         120   9e-28
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]                   117   7e-27
gi|225903437 glycogen synthase kinase 3 beta isoform 2 [Homo sap...   115   5e-26
gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]           114   8e-26
gi|21361340 glycogen synthase kinase 3 beta isoform 1 [Homo sapi...   114   1e-25
gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]        113   2e-25
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]             110   2e-24
gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]        110   2e-24
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]        109   2e-24
gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo ...   108   5e-24
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]        108   5e-24
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]           108   6e-24
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s...   107   1e-23
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s...   107   1e-23
gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo s...   105   3e-23
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]                   105   4e-23
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]         104   9e-23
gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]         104   9e-23
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]                   103   1e-22
gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens]             103   1e-22
gi|27477122 intestinal cell kinase [Homo sapiens]                     101   6e-22
gi|7662388 intestinal cell kinase [Homo sapiens]                      101   6e-22
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]              99   3e-21
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]               99   3e-21
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]           99   4e-21
gi|11496279 male germ cell-associated kinase [Homo sapiens]            99   5e-21

>gi|29570793 casein kinase II alpha 1 subunit isoform b [Homo
           sapiens]
          Length = 255

 Score =  531 bits (1367), Expect = e-151
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY
Sbjct: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD
Sbjct: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR
Sbjct: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180

Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240
           EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA
Sbjct: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240

Query: 241 NPLGMPVPAAAGAQQ 255
           NPLGMPVPAAAGAQQ
Sbjct: 241 NPLGMPVPAAAGAQQ 255


>gi|4503095 casein kinase II alpha 1 subunit isoform a [Homo
           sapiens]
          Length = 391

 Score =  531 bits (1367), Expect = e-151
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY
Sbjct: 137 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 196

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD
Sbjct: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR
Sbjct: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316

Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240
           EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA
Sbjct: 317 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 376

Query: 241 NPLGMPVPAAAGAQQ 255
           NPLGMPVPAAAGAQQ
Sbjct: 377 NPLGMPVPAAAGAQQ 391


>gi|29570791 casein kinase II alpha 1 subunit isoform a [Homo
           sapiens]
          Length = 391

 Score =  531 bits (1367), Expect = e-151
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY
Sbjct: 137 MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 196

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD
Sbjct: 197 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 256

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR
Sbjct: 257 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 316

Query: 181 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 240
           EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA
Sbjct: 317 EAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAA 376

Query: 241 NPLGMPVPAAAGAQQ 255
           NPLGMPVPAAAGAQQ
Sbjct: 377 NPLGMPVPAAAGAQQ 391


>gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens]
          Length = 350

 Score =  374 bits (960), Expect = e-104
 Identities = 171/197 (86%), Positives = 186/197 (94%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MYE+LKALDYCHS GIMHRDVKPHNVMIDH+ +KLRLIDWGLAEFYHP QEYNVRVASRY
Sbjct: 138 MYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRY 197

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           FKGPELLVDYQMYDYSLDMWSLGCMLASMIFR+EPFFHG DNYDQLVRIAKVLGTE+LY 
Sbjct: 198 FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYG 257

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           Y+ KY+I+LDP FNDILG+HSRKRWE F+HSEN+HLVSPEALD LDKLLRYDHQ RLTA+
Sbjct: 258 YLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAK 317

Query: 181 EAMEHPYFYTVVKDQAR 197
           EAMEHPYFY VVK+Q++
Sbjct: 318 EAMEHPYFYPVVKEQSQ 334


>gi|4506085 mitogen-activated protein kinase 13 [Homo sapiens]
          Length = 365

 Score =  120 bits (302), Expect = 9e-28
 Identities = 66/188 (35%), Positives = 111/188 (59%), Gaps = 10/188 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           +Y++LK L Y HS G++HRD+KP N+ ++ E  +L+++D+GLA   H   E    V +R+
Sbjct: 131 VYQMLKGLKYIHSAGVVHRDLKPGNLAVN-EDCELKILDFGLAR--HADAEMTGYVVTRW 187

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+++ +  Y+ ++D+WS+GC++A M+  K   F G D  DQL +I KV G     +
Sbjct: 188 YRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGK-TLFKGKDYLDQLTQILKVTGVPGT-E 245

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           ++ K N +    +   L +  RK + +          SP+A D L+K+L  D   RLTA 
Sbjct: 246 FVQKLNDKAAKSYIQSLPQTPRKDFTQLFPR-----ASPQAADLLEKMLELDVDKRLTAA 300

Query: 181 EAMEHPYF 188
           +A+ HP+F
Sbjct: 301 QALTHPFF 308


>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
          Length = 305

 Score =  117 bits (294), Expect = 7e-27
 Identities = 67/191 (35%), Positives = 112/191 (58%), Gaps = 15/191 (7%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           ++++L+ + +CHS  ++HRD+KP N++I+ E   ++L D+GLA  F  P + Y   V + 
Sbjct: 108 LFQLLQGVSFCHSHRVIHRDLKPQNLLIN-ELGAIKLADFGLARAFGVPLRTYTHEVVTL 166

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT--ED 117
           +++ PE+L+  + Y  ++D+WS+GC+ A M+ RK   F G    DQL RI ++LGT  ED
Sbjct: 167 WYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRK-ALFPGDSEIDQLFRIFRMLGTPSED 225

Query: 118 LYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRL 177
            +  + +      P +     + +RK  E  V +     + PE  D L +LL+YD   R+
Sbjct: 226 TWPGVTQL-----PDYKGSFPKWTRKGLEEIVPN-----LEPEGRDLLMQLLQYDPSQRI 275

Query: 178 TAREAMEHPYF 188
           TA+ A+ HPYF
Sbjct: 276 TAKTALAHPYF 286


>gi|225903437 glycogen synthase kinase 3 beta isoform 2 [Homo
           sapiens]
          Length = 420

 Score =  115 bits (287), Expect = 5e-26
 Identities = 77/250 (30%), Positives = 120/250 (48%), Gaps = 25/250 (10%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY++ ++L Y HS GI HRD+KP N+++D +   L+L D+G A+    G+     + SRY
Sbjct: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 221

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PEL+     Y  S+D+WS GC+LA ++   +P F G    DQLV I KVLGT     
Sbjct: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTP---- 276

Query: 121 YIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179
              +   E++P + +    +     W +           PEA+    +LL Y   +RLT 
Sbjct: 277 -TREQIREMNPNYTEFKFPQIKAHPWTKVFRPR----TPPEAIALCSRLLEYTPTARLTP 331

Query: 180 REAMEHPYFYTVVKDQARMGSSSMPGG---------STPVSSANMMSGISSVPTPSPLGP 230
            EA  H +F     D+ R  +  +P G         +T   S+N       +P  + +  
Sbjct: 332 LEACAHSFF-----DELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQA 386

Query: 231 LAGSPVIAAA 240
            A +P  A A
Sbjct: 387 AASTPTNATA 396


>gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]
          Length = 483

 Score =  114 bits (285), Expect = 8e-26
 Identities = 71/223 (31%), Positives = 110/223 (49%), Gaps = 16/223 (7%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY++ ++L Y HS G+ HRD+KP N+++D +   L+L D+G A+    G+     + SRY
Sbjct: 225 MYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 284

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PEL+     Y  S+D+WS GC+LA ++   +P F G    DQLV I KVLGT     
Sbjct: 285 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTP---- 339

Query: 121 YIDKYNIELDPRFNDI-LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTA 179
              +   E++P + +    +     W +   S       PEA+     LL Y   SRL+ 
Sbjct: 340 -TREQIREMNPNYTEFKFPQIKAHPWTKVFKSR----TPPEAIALCSSLLEYTPSSRLSP 394

Query: 180 REAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSV 222
            EA  H +F     D+ R   + +P         N  +G  S+
Sbjct: 395 LEACAHSFF-----DELRCLGTQLPNNRPLPPLFNFSAGELSI 432


>gi|21361340 glycogen synthase kinase 3 beta isoform 1 [Homo
           sapiens]
          Length = 433

 Score =  114 bits (284), Expect = 1e-25
 Identities = 81/258 (31%), Positives = 120/258 (46%), Gaps = 28/258 (10%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY++ ++L Y HS GI HRD+KP N+++D +   L+L D+G A+    G+     + SRY
Sbjct: 162 MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRY 221

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---ED 117
           ++ PEL+     Y  S+D+WS GC+LA ++   +P F G    DQLV I KVLGT   E 
Sbjct: 222 YRAPELIFGATDYTSSIDVWSAGCVLAELLL-GQPIFPGDSGVDQLVEIIKVLGTPTREQ 280

Query: 118 LYDYIDKY------NIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRY 171
           + +    Y       I+  P   D  G        R           PEA+    +LL Y
Sbjct: 281 IREMNPNYTEFKFPQIKAHPWTKDSSGTGHFTSGVRVFRPR----TPPEAIALCSRLLEY 336

Query: 172 DHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGG---------STPVSSANMMSGISSV 222
              +RLT  EA  H +F     D+ R  +  +P G         +T   S+N       +
Sbjct: 337 TPTARLTPLEACAHSFF-----DELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILI 391

Query: 223 PTPSPLGPLAGSPVIAAA 240
           P  + +   A +P  A A
Sbjct: 392 PPHARIQAAASTPTNATA 409


>gi|48255970 mitogen-activated protein kinase 12 [Homo sapiens]
          Length = 367

 Score =  113 bits (282), Expect = 2e-25
 Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 10/188 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           +Y++LK L Y H+ GI+HRD+KP N+ ++ E  +L+++D+GLA       E    V +R+
Sbjct: 134 VYQMLKGLRYIHAAGIIHRDLKPGNLAVN-EDCELKILDFGLAR--QADSEMTGYVVTRW 190

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+++++  Y  ++D+WS+GC++A MI  K   F G D+ DQL  I KV GT    +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK-TLFKGSDHLDQLKEIMKVTGTPPA-E 248

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
           ++ +   +    +   L    +K +   + +      SP A++ L+K+L  D + R+TA 
Sbjct: 249 FVQRLQSDEAKNYMKGLPELEKKDFASILTN-----ASPLAVNLLEKMLVLDAEQRVTAG 303

Query: 181 EAMEHPYF 188
           EA+ HPYF
Sbjct: 304 EALAHPYF 311


>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
          Length = 297

 Score =  110 bits (274), Expect = 2e-24
 Identities = 62/190 (32%), Positives = 105/190 (55%), Gaps = 13/190 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           +Y+IL+ + +CHS  ++HRD+KP N++ID +   ++L D+GLA  F  P + Y   V + 
Sbjct: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEVVTL 167

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
           +++ PE+L+    Y   +D+WS+G + A +   K+P FHG    DQL RI + LGT    
Sbjct: 168 WYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKKPLFHGDSEIDQLFRIFRALGTP--- 223

Query: 120 DYIDKYNIELDPRFNDILG-RHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178
                 N E+ P    +   +++  +W+    + +   +    LD L K+L YD   R++
Sbjct: 224 ------NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277

Query: 179 AREAMEHPYF 188
            + A+ HPYF
Sbjct: 278 GKMALNHPYF 287


>gi|20128774 mitogen-activated protein kinase 11 [Homo sapiens]
          Length = 364

 Score =  110 bits (274), Expect = 2e-24
 Identities = 64/188 (34%), Positives = 110/188 (58%), Gaps = 10/188 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           +Y++L+ L Y HS GI+HRD+KP NV ++ E  +LR++D+GLA      +E    VA+R+
Sbjct: 131 VYQLLRGLKYIHSAGIIHRDLKPSNVAVN-EDCELRILDFGLAR--QADEEMTGYVATRW 187

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+++++  Y+ ++D+WS+GC++A ++ + +  F G D  DQL RI +V+GT    +
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELL-QGKALFPGSDYIDQLKRIMEVVGTPS-PE 245

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
            + K + E    +   L    +K         N     P A+D L ++L  D   R++A 
Sbjct: 246 VLAKISSEHARTYIQSLPPMPQKDLSSIFRGAN-----PLAIDLLGRMLVLDSDQRVSAA 300

Query: 181 EAMEHPYF 188
           EA+ H YF
Sbjct: 301 EALAHAYF 308


>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
          Length = 298

 Score =  109 bits (273), Expect = 2e-24
 Identities = 63/195 (32%), Positives = 108/195 (55%), Gaps = 13/195 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           ++++L+ L +CHS  ++HRD+KP N++I+ E   ++L D+GLA  F  P + Y   V + 
Sbjct: 108 LFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-IKLADFGLARAFGVPVRTYTHEVVTL 166

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
           +++ PE+L+  + Y  ++D+WSLGC+ A M+ R+   F G    DQL RI + LGT D  
Sbjct: 167 WYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRR-ALFPGDSEIDQLFRIFRTLGTPDEV 225

Query: 120 DYIDKYNI-ELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178
            +    ++ +  P F          +W R   S+    +  +    L ++L YD   R++
Sbjct: 226 VWPGVTSMPDYKPSF---------PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRIS 276

Query: 179 AREAMEHPYFYTVVK 193
           A+ A+ HP+F  V K
Sbjct: 277 AKAALAHPFFQDVTK 291


>gi|20986512 mitogen-activated protein kinase 14 isoform 2 [Homo
           sapiens]
          Length = 360

 Score =  108 bits (270), Expect = 5e-24
 Identities = 61/188 (32%), Positives = 110/188 (58%), Gaps = 10/188 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           +Y+IL+ L Y HS  I+HRD+KP N+ ++ E  +L+++D+GLA   H   E    VA+R+
Sbjct: 131 IYQILRGLKYIHSADIIHRDLKPSNLAVN-EDCELKILDFGLAR--HTDDEMTGYVATRW 187

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+++++  Y+ ++D+WS+GC++A ++  +   F G D+ DQL  I +++GT    +
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR-TLFPGTDHIDQLKLILRLVGTPGA-E 245

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
            + K + E    +   L +  +  +       N     P A+D L+K+L  D   R+TA 
Sbjct: 246 LLKKISSESARNYIQSLTQMPKMNFANVFIGAN-----PLAVDLLEKMLVLDSDKRITAA 300

Query: 181 EAMEHPYF 188
           +A+ H YF
Sbjct: 301 QALAHAYF 308


>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
          Length = 346

 Score =  108 bits (270), Expect = 5e-24
 Identities = 63/189 (33%), Positives = 107/189 (56%), Gaps = 11/189 (5%)

Query: 4   ILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHP--GQEYNVRVASRYF 61
           +LK + +CH+  I+HRD+KP N++I    + L++ D+GLA  + P   + Y  +VA+R++
Sbjct: 111 LLKGVAFCHANNIVHRDLKPANLLISASGQ-LKIADFGLARVFSPDGSRLYTHQVATRWY 169

Query: 62  KGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDY 121
           + PELL   + YD  +D+WS+GC++  ++    P F G ++ +QL  + ++LGT +   +
Sbjct: 170 RAPELLYGARQYDQGVDLWSVGCIMGELL-NGSPLFPGKNDIEQLCYVLRILGTPNPQVW 228

Query: 122 IDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTARE 181
            +   +   P +N I    S K        E    VSP+ALD L + L Y    R+ A +
Sbjct: 229 PELTEL---PDYNKI----SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASK 281

Query: 182 AMEHPYFYT 190
           A+ H YF+T
Sbjct: 282 ALLHQYFFT 290


>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
          Length = 297

 Score =  108 bits (269), Expect = 6e-24
 Identities = 61/190 (32%), Positives = 104/190 (54%), Gaps = 13/190 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           +Y+IL+ + +CHS  ++HRD+KP N++ID +   ++L D+GLA  F  P + Y     + 
Sbjct: 109 LYQILQGIVFCHSRRVLHRDLKPQNLLID-DKGTIKLADFGLARAFGIPIRVYTHEAITL 167

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
           +++ PE+L+    Y   +D+WS+G + A +   K+P FHG    DQL RI + LGT    
Sbjct: 168 WYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKKPLFHGDSEIDQLFRIFRALGTP--- 223

Query: 120 DYIDKYNIELDPRFNDILG-RHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT 178
                 N E+ P    +   +++  +W+    + +   +    LD L K+L YD   R++
Sbjct: 224 ------NNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277

Query: 179 AREAMEHPYF 188
            + A+ HPYF
Sbjct: 278 GKMALNHPYF 287


>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 357

 Score =  107 bits (267), Expect = 1e-23
 Identities = 63/205 (30%), Positives = 109/205 (53%), Gaps = 12/205 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56
           +Y+IL+ L Y HS  ++HRD+KP N++I+     L++ D+GLA    P  ++       V
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTTC-DLKICDFGLARIADPEHDHTGFLTEYV 205

Query: 57  ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116
           A+R+++ PE++++ + Y  S+D+WS+GC+LA M+  + P F G    DQL  I  +LG+ 
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 264

Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176
              D     N++    +   L   ++  W +     +      +ALD LD++L ++   R
Sbjct: 265 SQEDLNCIINMKA-RNYLQSLPSKTKVAWAKLFPKSDS-----KALDLLDRMLTFNPNKR 318

Query: 177 LTAREAMEHPYFYTVVKDQARMGSS 201
           +T  EA+ HPY          +G S
Sbjct: 319 ITVEEALAHPYLEQYYDPTDEVGQS 343


>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 379

 Score =  107 bits (266), Expect = 1e-23
 Identities = 61/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56
           +Y+IL+ L Y HS  ++HRD+KP N++I+     L++ D+GLA    P  ++       V
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTTC-DLKICDFGLARIADPEHDHTGFLTEYV 205

Query: 57  ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116
           A+R+++ PE++++ + Y  S+D+WS+GC+LA M+  + P F G    DQL  I  +LG+ 
Sbjct: 206 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 264

Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176
              D     N++    +   L   ++  W +     +      +ALD LD++L ++   R
Sbjct: 265 SQEDLNCIINMKA-RNYLQSLPSKTKVAWAKLFPKSDS-----KALDLLDRMLTFNPNKR 318

Query: 177 LTAREAMEHPY 187
           +T  EA+ HPY
Sbjct: 319 ITVEEALAHPY 329


>gi|4503069 mitogen-activated protein kinase 14 isoform 1 [Homo
           sapiens]
          Length = 360

 Score =  105 bits (263), Expect = 3e-23
 Identities = 60/188 (31%), Positives = 109/188 (57%), Gaps = 10/188 (5%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           +Y+IL+ L Y HS  I+HRD+KP N+ ++ E  +L+++D+GLA   H   E    VA+R+
Sbjct: 131 IYQILRGLKYIHSADIIHRDLKPSNLAVN-EDCELKILDFGLAR--HTDDEMTGYVATRW 187

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+++++  Y+ ++D+WS+GC++A ++  +   F G D+ +QL +I ++ GT   Y 
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGR-TLFPGTDHINQLQQIMRLTGTPPAY- 245

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAR 180
            I++        +   L +  +  +       N     P A+D L+K+L  D   R+TA 
Sbjct: 246 LINRMPSHEARNYIQSLTQMPKMNFANVFIGAN-----PLAVDLLEKMLVLDSDKRITAA 300

Query: 181 EAMEHPYF 188
           +A+ H YF
Sbjct: 301 QALAHAYF 308


>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
          Length = 292

 Score =  105 bits (262), Expect = 4e-23
 Identities = 61/193 (31%), Positives = 107/193 (55%), Gaps = 18/193 (9%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           ++++LK L +CHS  ++HRD+KP N++I+  + +L+L D+GLA  F  P + Y+  V + 
Sbjct: 107 LFQLLKGLGFCHSRNVLHRDLKPQNLLINR-NGELKLADFGLARAFGIPVRCYSAEVVTL 165

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
           +++ P++L   ++Y  S+DMWS GC+ A +     P F G+D  DQL RI ++LGT    
Sbjct: 166 WYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGT---- 221

Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPE----ALDFLDKLLRYDHQS 175
                     + ++  +      K +  +  + +   V P+      D L  LL+ +   
Sbjct: 222 --------PTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQ 273

Query: 176 RLTAREAMEHPYF 188
           R++A EA++HPYF
Sbjct: 274 RISAEEALQHPYF 286


>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  104 bits (259), Expect = 9e-23
 Identities = 60/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56
           +Y+IL+ L Y HS  ++HRD+KP N++++     L++ D+GLA    P  ++       V
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTC-DLKICDFGLARVADPDHDHTGFLTEYV 188

Query: 57  ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116
           A+R+++ PE++++ + Y  S+D+WS+GC+LA M+  + P F G    DQL  I  +LG+ 
Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 247

Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176
              D     N++    +   L   ++  W R   + +      +ALD LDK+L ++   R
Sbjct: 248 SQEDLNCIINLKA-RNYLLSLPHKNKVPWNRLFPNADS-----KALDLLDKMLTFNPHKR 301

Query: 177 LTAREAMEHPY 187
           +   +A+ HPY
Sbjct: 302 IEVEQALAHPY 312


>gi|66932916 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score =  104 bits (259), Expect = 9e-23
 Identities = 60/191 (31%), Positives = 106/191 (55%), Gaps = 12/191 (6%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYN----VRV 56
           +Y+IL+ L Y HS  ++HRD+KP N++++     L++ D+GLA    P  ++       V
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTC-DLKICDFGLARVADPDHDHTGFLTEYV 188

Query: 57  ASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTE 116
           A+R+++ PE++++ + Y  S+D+WS+GC+LA M+  + P F G    DQL  I  +LG+ 
Sbjct: 189 ATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGILGSP 247

Query: 117 DLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSR 176
              D     N++    +   L   ++  W R   + +      +ALD LDK+L ++   R
Sbjct: 248 SQEDLNCIINLKA-RNYLLSLPHKNKVPWNRLFPNADS-----KALDLLDKMLTFNPHKR 301

Query: 177 LTAREAMEHPY 187
           +   +A+ HPY
Sbjct: 302 IEVEQALAHPY 312


>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
          Length = 346

 Score =  103 bits (258), Expect = 1e-22
 Identities = 63/192 (32%), Positives = 106/192 (55%), Gaps = 18/192 (9%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE-FYHPGQEYNVRVASR 59
           M   L+ L+Y H   I+HRD+KP+N+++D E+  L+L D+GLA+ F  P + Y  +V +R
Sbjct: 118 MLMTLQGLEYLHQHWILHRDLKPNNLLLD-ENGVLKLADFGLAKSFGSPNRAYTHQVVTR 176

Query: 60  YFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLY 119
           +++ PELL   +MY   +DMW++GC+LA ++ R  PF  G  + DQL RI + LGT    
Sbjct: 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLR-VPFLPGDSDLDQLTRIFETLGT---- 231

Query: 120 DYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVS---PEALDFLDKLLRYDHQSR 176
                     + ++ D+        ++ F      H+ S    + LD +  L  ++  +R
Sbjct: 232 --------PTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCAR 283

Query: 177 LTAREAMEHPYF 188
           +TA +A++  YF
Sbjct: 284 ITATQALKMKYF 295


>gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens]
          Length = 419

 Score =  103 bits (257), Expect = 1e-22
 Identities = 65/212 (30%), Positives = 105/212 (49%), Gaps = 24/212 (11%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY++ K+LD+ H  GI HRDVKP N++I  +   L+L D+G     +  Q Y   +++R+
Sbjct: 109 MYQLCKSLDHIHRNGIFHRDVKPENILIKQD--VLKLGDFGSCRSVYSKQPYTEYISTRW 166

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE L+    Y Y +D+WS GC+    I   +P F G +  DQ+ +I  V+GT     
Sbjct: 167 YRAPECLLTDGFYTYKMDLWSAGCVFYE-IASLQPLFPGVNELDQISKIHDVIGTP-AQK 224

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHL------VSPEALDFLDKLLRYDHQ 174
            + K+             + SR     F   +   +      +SP+ L  L  ++ YD  
Sbjct: 225 ILTKF-------------KQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPD 271

Query: 175 SRLTAREAMEHPYFYTVVKDQAR-MGSSSMPG 205
            R+ A +A++HPYF    K + R +GS    G
Sbjct: 272 ERIAAHQALQHPYFQEQRKTEKRALGSHRKAG 303


>gi|27477122 intestinal cell kinase [Homo sapiens]
          Length = 632

 Score =  101 bits (252), Expect = 6e-22
 Identities = 58/191 (30%), Positives = 101/191 (52%), Gaps = 15/191 (7%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY+IL+ L + H  G  HRD+KP N++       +++ D+GLA        Y   V++R+
Sbjct: 106 MYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRW 164

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+L+    Y   +D+W++GC++A  ++   P F G    D + +I +VLGT    D
Sbjct: 165 YRAPEVLLRSTNYSSPIDVWAVGCIMAE-VYTLRPLFPGASEIDTIFKICQVLGTPKKTD 223

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177
           + + Y +     F          RW + V +  + L+   S EA+  L  +L++D + R 
Sbjct: 224 WPEGYQLSSAMNF----------RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273

Query: 178 TAREAMEHPYF 188
           TA +A+ +PYF
Sbjct: 274 TASQALRYPYF 284


>gi|7662388 intestinal cell kinase [Homo sapiens]
          Length = 632

 Score =  101 bits (252), Expect = 6e-22
 Identities = 58/191 (30%), Positives = 101/191 (52%), Gaps = 15/191 (7%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY+IL+ L + H  G  HRD+KP N++       +++ D+GLA        Y   V++R+
Sbjct: 106 MYQILQGLAFIHKHGFFHRDLKPENLLCMGPEL-VKIADFGLAREIRSKPPYTDYVSTRW 164

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+L+    Y   +D+W++GC++A  ++   P F G    D + +I +VLGT    D
Sbjct: 165 YRAPEVLLRSTNYSSPIDVWAVGCIMAE-VYTLRPLFPGASEIDTIFKICQVLGTPKKTD 223

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177
           + + Y +     F          RW + V +  + L+   S EA+  L  +L++D + R 
Sbjct: 224 WPEGYQLSSAMNF----------RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRP 273

Query: 178 TAREAMEHPYF 188
           TA +A+ +PYF
Sbjct: 274 TASQALRYPYF 284


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 66/195 (33%), Positives = 100/195 (51%), Gaps = 16/195 (8%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ--EYNVRVAS 58
           +Y+++KA+ +CH   I+HRD+KP N++I H +  L+L D+G A     G    Y   VA+
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISH-NDVLKLCDFGFARNLSEGNNANYTEYVAT 174

Query: 59  RYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDL 118
           R+++ PELL+    Y  S+DMWS+GC+L   +   +P F G    DQL  I KVLG    
Sbjct: 175 RWYRSPELLLG-APYGKSVDMWSVGCILGE-LSDGQPLFPGESEIDQLFTIQKVLGPLPS 232

Query: 119 YDYIDKYNIELDPRFNDI---LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175
                 Y+   +PRF+ +      H +    R++   N  L     LD +  LL+ D   
Sbjct: 233 EQMKLFYS---NPRFHGLRFPAVNHPQSLERRYLGILNSVL-----LDLMKNLLKLDPAD 284

Query: 176 RLTAREAMEHPYFYT 190
           R    + + HP F T
Sbjct: 285 RYLTEQCLNHPTFQT 299


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 66/195 (33%), Positives = 100/195 (51%), Gaps = 16/195 (8%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQ--EYNVRVAS 58
           +Y+++KA+ +CH   I+HRD+KP N++I H +  L+L D+G A     G    Y   VA+
Sbjct: 116 IYQLIKAIHWCHKNDIVHRDIKPENLLISH-NDVLKLCDFGFARNLSEGNNANYTEYVAT 174

Query: 59  RYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDL 118
           R+++ PELL+    Y  S+DMWS+GC+L   +   +P F G    DQL  I KVLG    
Sbjct: 175 RWYRSPELLLG-APYGKSVDMWSVGCILGE-LSDGQPLFPGESEIDQLFTIQKVLGPLPS 232

Query: 119 YDYIDKYNIELDPRFNDI---LGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQS 175
                 Y+   +PRF+ +      H +    R++   N  L     LD +  LL+ D   
Sbjct: 233 EQMKLFYS---NPRFHGLRFPAVNHPQSLERRYLGILNSVL-----LDLMKNLLKLDPAD 284

Query: 176 RLTAREAMEHPYFYT 190
           R    + + HP F T
Sbjct: 285 RYLTEQCLNHPTFQT 299


>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
          Length = 721

 Score = 99.0 bits (245), Expect = 4e-21
 Identities = 59/193 (30%), Positives = 101/193 (52%), Gaps = 16/193 (8%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVA--- 57
           MY++L+ L Y HS  ++HRD+KP N+ I+ E   L++ D+GLA    P   +   ++   
Sbjct: 133 MYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEGL 192

Query: 58  -SRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGH--DNYDQLVRIAKVLG 114
            +++++ P LL+    Y  ++DMW+ GC+ A M+  K  F   H  +    ++    V+ 
Sbjct: 193 VTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVH 252

Query: 115 TEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQ 174
            ED  + +    + +    ND+   H  K   + +       +S EALDFL+++L +   
Sbjct: 253 EEDRQELLSVIPVYIR---NDMTEPH--KPLTQLLPG-----ISREALDFLEQILTFSPM 302

Query: 175 SRLTAREAMEHPY 187
            RLTA EA+ HPY
Sbjct: 303 DRLTAEEALSHPY 315


>gi|11496279 male germ cell-associated kinase [Homo sapiens]
          Length = 623

 Score = 98.6 bits (244), Expect = 5e-21
 Identities = 64/242 (26%), Positives = 118/242 (48%), Gaps = 19/242 (7%)

Query: 1   MYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRY 60
           MY+IL+ L + H  G  HRD+KP N++       +++ D+GLA        Y   V++R+
Sbjct: 106 MYQILQGLAFIHKHGFFHRDMKPENLLCMGPEL-VKIADFGLARELRSQPPYTDYVSTRW 164

Query: 61  FKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYD 120
           ++ PE+L+   +Y   +D+W++G ++A  ++   P F G    D++ +I +VLGT    D
Sbjct: 165 YRAPEVLLRSSVYSSPIDVWAVGSIMAE-LYMLRPLFPGTSEVDEIFKICQVLGTPKKSD 223

Query: 121 YIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLV---SPEALDFLDKLLRYDHQSRL 177
           + + Y +     F          R+ + V    + L+   S EA+  + ++L +D + R 
Sbjct: 224 WPEGYQLASSMNF----------RFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRP 273

Query: 178 TAREAMEHPYFYT--VVKDQAR--MGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAG 233
           TA +A++HPYF    V+   +       S+     P+ S   +  +   P P  +  + G
Sbjct: 274 TASQALKHPYFQVGQVLGPSSNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVG 333

Query: 234 SP 235
            P
Sbjct: 334 QP 335


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,572,503
Number of Sequences: 37866
Number of extensions: 505027
Number of successful extensions: 4098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 2580
Number of HSP's gapped (non-prelim): 1112
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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