Guide to the Human Genome
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Search of human proteins with 29540551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29540551 trophinin isoform 2 [Homo sapiens]
         (706 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29540551 trophinin isoform 2 [Homo sapiens]                       1370   0.0  
gi|29540541 trophinin isoform 2 [Homo sapiens]                       1370   0.0  
gi|89276766 trophinin isoform 5 [Homo sapiens]                       1274   0.0  
gi|29171705 melanoma antigen family D, 2 [Homo sapiens]               395   e-110
gi|19387846 melanoma antigen family D, 2 [Homo sapiens]               395   e-110
gi|41350320 melanoma antigen family D, 2 [Homo sapiens]               395   e-110
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]    362   e-100
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    362   e-100
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    362   e-100
gi|149274614 melanoma antigen family D, 4 [Homo sapiens]              362   e-100
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]     343   2e-94
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]     343   2e-94
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]     343   2e-94
gi|20162572 necdin-like 2 [Homo sapiens]                              204   2e-52
gi|29826296 melanoma antigen family F, 1 [Homo sapiens]               196   6e-50
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]               194   2e-49
gi|148746206 MAGE-like protein 2 [Homo sapiens]                       193   4e-49
gi|4505349 necdin [Homo sapiens]                                      183   5e-46
gi|4505085 melanoma antigen family B, 4 [Homo sapiens]                183   5e-46
gi|73623441 melanoma antigen family B, 10 [Homo sapiens]              182   1e-45
gi|29171714 melanoma antigen family B, 3 [Homo sapiens]               179   1e-44
gi|153791873 melanoma antigen family B, 16 [Homo sapiens]             175   1e-43
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   171   2e-42
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   171   2e-42
gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   171   2e-42
gi|27734781 melanoma antigen family B, 18 [Homo sapiens]              169   6e-42
gi|58530863 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|10567820 melanoma antigen family A, 10 [Homo sapiens]              168   2e-41
gi|29171711 melanoma antigen family B, 1 [Homo sapiens]               166   9e-41
gi|29171709 melanoma antigen family B, 1 [Homo sapiens]               166   9e-41

>gi|29540551 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score = 1370 bits (3547), Expect = 0.0
 Identities = 706/706 (100%), Positives = 706/706 (100%)

Query: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60
           MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP
Sbjct: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60

Query: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120
           PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP
Sbjct: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120

Query: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180
           TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ
Sbjct: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180

Query: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240
           NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN
Sbjct: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240

Query: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300
           ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS
Sbjct: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300

Query: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360
           KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA
Sbjct: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360

Query: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420
           DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE
Sbjct: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420

Query: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480
           RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE
Sbjct: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480

Query: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540
           YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL
Sbjct: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540

Query: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600
           SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP
Sbjct: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600

Query: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660
           PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR
Sbjct: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660

Query: 661 AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM 706
           AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM
Sbjct: 661 AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM 706


>gi|29540541 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score = 1370 bits (3547), Expect = 0.0
 Identities = 706/706 (100%), Positives = 706/706 (100%)

Query: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60
           MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP
Sbjct: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60

Query: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120
           PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP
Sbjct: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120

Query: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180
           TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ
Sbjct: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180

Query: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240
           NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN
Sbjct: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240

Query: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300
           ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS
Sbjct: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300

Query: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360
           KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA
Sbjct: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360

Query: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420
           DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE
Sbjct: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420

Query: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480
           RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE
Sbjct: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480

Query: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540
           YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL
Sbjct: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540

Query: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600
           SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP
Sbjct: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600

Query: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660
           PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR
Sbjct: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660

Query: 661 AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM 706
           AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM
Sbjct: 661 AEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHSSQGSYGQSAEGVM 706


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score = 1275 bits (3298), Expect = 0.0
 Identities = 662/662 (100%), Positives = 662/662 (100%)

Query: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60
           MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP
Sbjct: 1   MDRRNDYGYRVPLFQGPLPPPGSLGLPFPPDIQTETTEEDSVLLMHTLLAATKDSLAMDP 60

Query: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120
           PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP
Sbjct: 61  PVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANEIATNKPKITWQALNLPVITQISQALP 120

Query: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180
           TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ
Sbjct: 121 TTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQ 180

Query: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240
           NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN
Sbjct: 181 NIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITN 240

Query: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300
           ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS
Sbjct: 241 ETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKS 300

Query: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360
           KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA
Sbjct: 301 KGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNA 360

Query: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420
           DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE
Sbjct: 361 DQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHLNGDE 420

Query: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480
           RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE
Sbjct: 421 RSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDE 480

Query: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540
           YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL
Sbjct: 481 YFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVIL 540

Query: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600
           SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP
Sbjct: 541 SVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRP 600

Query: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660
           PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR
Sbjct: 601 PEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660

Query: 661 AE 662
           AE
Sbjct: 661 AE 662


>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  395 bits (1014), Expect = e-110
 Identities = 236/502 (47%), Positives = 307/502 (61%), Gaps = 45/502 (8%)

Query: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81

Query: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130

Query: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188

Query: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248

Query: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297

Query: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357

Query: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417

Query: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477

Query: 642 AVEMEVQAAAVAVAEAEARAEI 663
           A+E +++AAA A AEA+ARAEI
Sbjct: 478 AMEADLKAAAEAAAEAKARAEI 499



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/236 (19%), Positives = 87/236 (36%), Gaps = 24/236 (10%)

Query: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRP-KKSKTKKAPIKTITKAAPAAPPVPA 91
           Q E +E+DS  +M TLL  T++    + P  ++  + S+  K    +    A      P 
Sbjct: 15  QAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPE 74

Query: 92  ANEIATNKPKITWQALNLPVITQISQALPT-TEVTNTQASSVTAQPKKANKMK-----RV 145
           A E    +   T Q  +  V+   +++L   T+  N    +VT    +  K+      +V
Sbjct: 75  AREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKV 134

Query: 146 TAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKA 205
             KA +   +P+       + +S                  A +S  +Q     +K KKA
Sbjct: 135 NTKAQETEAAPSQAPADEPEPES-----------------AAAQSQENQDTRPKVKAKKA 177

Query: 206 SKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261
            K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233


>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  395 bits (1014), Expect = e-110
 Identities = 236/502 (47%), Positives = 307/502 (61%), Gaps = 45/502 (8%)

Query: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81

Query: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130

Query: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188

Query: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248

Query: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297

Query: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357

Query: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417

Query: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477

Query: 642 AVEMEVQAAAVAVAEAEARAEI 663
           A+E +++AAA A AEA+ARAEI
Sbjct: 478 AMEADLKAAAEAAAEAKARAEI 499



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/236 (19%), Positives = 87/236 (36%), Gaps = 24/236 (10%)

Query: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRP-KKSKTKKAPIKTITKAAPAAPPVPA 91
           Q E +E+DS  +M TLL  T++    + P  ++  + S+  K    +    A      P 
Sbjct: 15  QAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPE 74

Query: 92  ANEIATNKPKITWQALNLPVITQISQALPT-TEVTNTQASSVTAQPKKANKMK-----RV 145
           A E    +   T Q  +  V+   +++L   T+  N    +VT    +  K+      +V
Sbjct: 75  AREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKV 134

Query: 146 TAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKA 205
             KA +   +P+       + +S                  A +S  +Q     +K KKA
Sbjct: 135 NTKAQETEAAPSQAPADEPEPES-----------------AAAQSQENQDTRPKVKAKKA 177

Query: 206 SKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261
            K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233


>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score =  395 bits (1014), Expect = e-110
 Identities = 236/502 (47%), Positives = 307/502 (61%), Gaps = 45/502 (8%)

Query: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81

Query: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130

Query: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188

Query: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248

Query: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297

Query: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357

Query: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417

Query: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477

Query: 642 AVEMEVQAAAVAVAEAEARAEI 663
           A+E +++AAA A AEA+ARAEI
Sbjct: 478 AMEADLKAAAEAAAEAKARAEI 499



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 45/236 (19%), Positives = 87/236 (36%), Gaps = 24/236 (10%)

Query: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRP-KKSKTKKAPIKTITKAAPAAPPVPA 91
           Q E +E+DS  +M TLL  T++    + P  ++  + S+  K    +    A      P 
Sbjct: 15  QAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPE 74

Query: 92  ANEIATNKPKITWQALNLPVITQISQALPT-TEVTNTQASSVTAQPKKANKMK-----RV 145
           A E    +   T Q  +  V+   +++L   T+  N    +VT    +  K+      +V
Sbjct: 75  AREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKV 134

Query: 146 TAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKA 205
             KA +   +P+       + +S                  A +S  +Q     +K KKA
Sbjct: 135 NTKAQETEAAPSQAPADEPEPES-----------------AAAQSQENQDTRPKVKAKKA 177

Query: 206 SKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261
            K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233


>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
          Length = 739

 Score =  362 bits (929), Expect = e-100
 Identities = 232/575 (40%), Positives = 315/575 (54%), Gaps = 93/575 (16%)

Query: 165 QLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSL 224
           +L++P+    L    Q     +ANE+A+  A +      +A+ + +AA  A A+A     
Sbjct: 75  ELENPVLAQTLVEALQLDPETLANETAARAANVA-----RAAASNRAARAAAAAARTAFS 129

Query: 225 AATATHTATTQGQITNETASIHTTAASIR--TKKASKARKTIAKVINTDTEHIEALNVTD 282
              A+H   T  Q++ E     T AA  +  T +   A    ++++ T          T 
Sbjct: 130 QVVASHRVATP-QVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATS 188

Query: 283 AATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATL------- 335
           A ++             S  ++AA+ GP+S    S+AP A ++  N+   A L       
Sbjct: 189 AQSQT-----------GSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFLGQNDVFD 237

Query: 336 -------------RVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSA----- 377
                        R KR + A++AAT+  +  S  P    G +      +T  S      
Sbjct: 238 FTQPAGVSGMAFPRPKRPAPAQEAATEGPSAASGVPQTGPGREVAATRPKTTKSGKALAK 297

Query: 378 ---LETQ---VAAAVQAL----------ADDYLAQLSLEPTTRTRGKRNRKSKHLNGDER 421
              +E Q    AAA +A           A    AQ S EP  R  GKR +KSKHL+ +  
Sbjct: 298 TRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLDDEYE 357

Query: 422 SGSNYRRIP-----W-------------GRRPA---------------PPRDVAILQERA 448
           S    R  P     W               RP                PPR+V +LQERA
Sbjct: 358 SSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERA 417

Query: 449 NKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQS 508
           NKLVKYL++KD  KIPIKR+DML+DVI+EYDE+FPEIIERA+YTLEK F ++LKEIDK+ 
Sbjct: 418 NKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEE 477

Query: 509 SLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGV 568
            LYIL+ T++SSA +LG TKDTP+L LL+VIL VIFMNGN+ASEAV+WE LRK+GLRPGV
Sbjct: 478 HLYILVCTRDSSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGV 537

Query: 569 RHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQ 628
           RH   G++RKLITD+FVKQKYLEYK++PNS PPEYEF WGLR+ HETSKM+VL+F  + Q
Sbjct: 538 RHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQ 597

Query: 629 KKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEI 663
            +DP++W   + EAV+   +   V +AE  ARA++
Sbjct: 598 NRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQM 632


>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  362 bits (929), Expect = e-100
 Identities = 232/575 (40%), Positives = 315/575 (54%), Gaps = 93/575 (16%)

Query: 165 QLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSL 224
           +L++P+    L    Q     +ANE+A+  A +      +A+ + +AA  A A+A     
Sbjct: 75  ELENPVLAQTLVEALQLDPETLANETAARAANVA-----RAAASNRAARAAAAAARTAFS 129

Query: 225 AATATHTATTQGQITNETASIHTTAASIR--TKKASKARKTIAKVINTDTEHIEALNVTD 282
              A+H   T  Q++ E     T AA  +  T +   A    ++++ T          T 
Sbjct: 130 QVVASHRVATP-QVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATS 188

Query: 283 AATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATL------- 335
           A ++             S  ++AA+ GP+S    S+AP A ++  N+   A L       
Sbjct: 189 AQSQT-----------GSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFLGQNDVFD 237

Query: 336 -------------RVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSA----- 377
                        R KR + A++AAT+  +  S  P    G +      +T  S      
Sbjct: 238 FTQPAGVSGMAFPRPKRPAPAQEAATEGPSAASGVPQTGPGREVAATRPKTTKSGKALAK 297

Query: 378 ---LETQ---VAAAVQAL----------ADDYLAQLSLEPTTRTRGKRNRKSKHLNGDER 421
              +E Q    AAA +A           A    AQ S EP  R  GKR +KSKHL+ +  
Sbjct: 298 TRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLDDEYE 357

Query: 422 SGSNYRRIP-----W-------------GRRPA---------------PPRDVAILQERA 448
           S    R  P     W               RP                PPR+V +LQERA
Sbjct: 358 SSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERA 417

Query: 449 NKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQS 508
           NKLVKYL++KD  KIPIKR+DML+DVI+EYDE+FPEIIERA+YTLEK F ++LKEIDK+ 
Sbjct: 418 NKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEE 477

Query: 509 SLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGV 568
            LYIL+ T++SSA +LG TKDTP+L LL+VIL VIFMNGN+ASEAV+WE LRK+GLRPGV
Sbjct: 478 HLYILVCTRDSSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGV 537

Query: 569 RHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQ 628
           RH   G++RKLITD+FVKQKYLEYK++PNS PPEYEF WGLR+ HETSKM+VL+F  + Q
Sbjct: 538 RHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQ 597

Query: 629 KKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEI 663
            +DP++W   + EAV+   +   V +AE  ARA++
Sbjct: 598 NRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQM 632


>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  362 bits (929), Expect = e-100
 Identities = 232/575 (40%), Positives = 315/575 (54%), Gaps = 93/575 (16%)

Query: 165 QLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSL 224
           +L++P+    L    Q     +ANE+A+  A +      +A+ + +AA  A A+A     
Sbjct: 75  ELENPVLAQTLVEALQLDPETLANETAARAANVA-----RAAASNRAARAAAAAARTAFS 129

Query: 225 AATATHTATTQGQITNETASIHTTAASIR--TKKASKARKTIAKVINTDTEHIEALNVTD 282
              A+H   T  Q++ E     T AA  +  T +   A    ++++ T          T 
Sbjct: 130 QVVASHRVATP-QVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATS 188

Query: 283 AATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATL------- 335
           A ++             S  ++AA+ GP+S    S+AP A ++  N+   A L       
Sbjct: 189 AQSQT-----------GSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFLGQNDVFD 237

Query: 336 -------------RVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSA----- 377
                        R KR + A++AAT+  +  S  P    G +      +T  S      
Sbjct: 238 FTQPAGVSGMAFPRPKRPAPAQEAATEGPSAASGVPQTGPGREVAATRPKTTKSGKALAK 297

Query: 378 ---LETQ---VAAAVQAL----------ADDYLAQLSLEPTTRTRGKRNRKSKHLNGDER 421
              +E Q    AAA +A           A    AQ S EP  R  GKR +KSKHL+ +  
Sbjct: 298 TRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLDDEYE 357

Query: 422 SGSNYRRIP-----W-------------GRRPA---------------PPRDVAILQERA 448
           S    R  P     W               RP                PPR+V +LQERA
Sbjct: 358 SSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERA 417

Query: 449 NKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQS 508
           NKLVKYL++KD  KIPIKR+DML+DVI+EYDE+FPEIIERA+YTLEK F ++LKEIDK+ 
Sbjct: 418 NKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEE 477

Query: 509 SLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGV 568
            LYIL+ T++SSA +LG TKDTP+L LL+VIL VIFMNGN+ASEAV+WE LRK+GLRPGV
Sbjct: 478 HLYILVCTRDSSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGV 537

Query: 569 RHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQ 628
           RH   G++RKLITD+FVKQKYLEYK++PNS PPEYEF WGLR+ HETSKM+VL+F  + Q
Sbjct: 538 RHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQ 597

Query: 629 KKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEI 663
            +DP++W   + EAV+   +   V +AE  ARA++
Sbjct: 598 NRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQM 632


>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
          Length = 739

 Score =  362 bits (929), Expect = e-100
 Identities = 232/575 (40%), Positives = 315/575 (54%), Gaps = 93/575 (16%)

Query: 165 QLKSPLQVLKLPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSL 224
           +L++P+    L    Q     +ANE+A+  A +      +A+ + +AA  A A+A     
Sbjct: 75  ELENPVLAQTLVEALQLDPETLANETAARAANVA-----RAAASNRAARAAAAAARTAFS 129

Query: 225 AATATHTATTQGQITNETASIHTTAASIR--TKKASKARKTIAKVINTDTEHIEALNVTD 282
              A+H   T  Q++ E     T AA  +  T +   A    ++++ T          T 
Sbjct: 130 QVVASHRVATP-QVSGEDTQPTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATS 188

Query: 283 AATRQIEASVVAIRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATL------- 335
           A ++             S  ++AA+ GP+S    S+AP A ++  N+   A L       
Sbjct: 189 AQSQT-----------GSPAQEAATEGPSSACAFSQAPCAREVDANRPSTAFLGQNDVFD 237

Query: 336 -------------RVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSA----- 377
                        R KR + A++AAT+  +  S  P    G +      +T  S      
Sbjct: 238 FTQPAGVSGMAFPRPKRPAPAQEAATEGPSAASGVPQTGPGREVAATRPKTTKSGKALAK 297

Query: 378 ---LETQ---VAAAVQAL----------ADDYLAQLSLEPTTRTRGKRNRKSKHLNGDER 421
              +E Q    AAA +A           A    AQ S EP  R  GKR +KSKHL+ +  
Sbjct: 298 TRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMGGKRTKKSKHLDDEYE 357

Query: 422 SGSNYRRIP-----W-------------GRRPA---------------PPRDVAILQERA 448
           S    R  P     W               RP                PPR+V +LQERA
Sbjct: 358 SSEEERETPAVPPTWRASQPSLTVRAQLAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERA 417

Query: 449 NKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQS 508
           NKLVKYL++KD  KIPIKR+DML+DVI+EYDE+FPEIIERA+YTLEK F ++LKEIDK+ 
Sbjct: 418 NKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEIDKEE 477

Query: 509 SLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGV 568
            LYIL+ T++SSA +LG TKDTP+L LL+VIL VIFMNGN+ASEAV+WE LRK+GLRPGV
Sbjct: 478 HLYILVCTRDSSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMGLRPGV 537

Query: 569 RHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQ 628
           RH   G++RKLITD+FVKQKYLEYK++PNS PPEYEF WGLR+ HETSKM+VL+F  + Q
Sbjct: 538 RHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQ 597

Query: 629 KKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAEI 663
            +DP++W   + EAV+   +   V +AE  ARA++
Sbjct: 598 NRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQM 632


>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
          Length = 834

 Score =  343 bits (881), Expect = 2e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 519 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 578

Query: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 579 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 638

Query: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 639 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 698

Query: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 699 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 745



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 73/267 (27%), Positives = 106/267 (39%), Gaps = 46/267 (17%)

Query: 180 QNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQIT 239
           Q+   P ANE A  Q    + +PK A K + A  K      + S A  A     TQ    
Sbjct: 108 QSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQ---- 163

Query: 240 NETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKK 299
                          K A K++    K  N   +  +A    + A  + E +        
Sbjct: 164 --------------PKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAF------- 202

Query: 300 SKGKKAASR-GPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTP 358
            K + A ++ GPN+    S++  A  +       A  R K   +A    TKA   ++QT 
Sbjct: 203 -KAQNATTKVGPNATYNFSQSLNANDL-------ANSRPKTPFKAWNDTTKAPTADTQTQ 254

Query: 359 NADQGAQAKIASAQTNVS---ALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKH 415
           N +   QAK+A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +
Sbjct: 255 NVN---QAKMATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINN 310

Query: 416 LNGDERSGSNYRRIP-----WGRRPAP 437
           LN +E S  + RR P     W   P P
Sbjct: 311 LNVEENSSGDQRRAPLAAGTWRSAPVP 337



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 77/308 (25%), Positives = 114/308 (37%), Gaps = 73/308 (23%)

Query: 35  ETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAANE 94
           E + EDS LLM TL+ A + S A  PP         T +A       A+P +   P ANE
Sbjct: 73  EASVEDSALLMQTLMEAIQISEA--PP---------TNQA----TAAASPQSSQPPTANE 117

Query: 95  IATNKPKITWQALNLPVITQISQALPTTEVTNTQASSVTAQPKKANKMKRVTAKAAQGSQ 154
           +A                             + Q S+  A+PK A K++  T K   G  
Sbjct: 118 MA-----------------------------DIQVSAAAARPKSAFKVQNATTKGPNGVY 148

Query: 155 S-PTGHEGGTIQLKSPLQVLKLPVISQNI-----HAPIANESASSQALITSIKPKKASKA 208
                H    +    P    K    SQN      +A      A++   + + K + A KA
Sbjct: 149 DFSQAHNAKDVPNTQPKAAFK----SQNATPKGPNAAYDFSQAATTGELAANKSEMAFKA 204

Query: 209 KKAANKAIASAT---EVSLAAT--ATHTATTQGQITNETASIHTTAASIRTKKASKARKT 263
           + A  K   +AT     SL A   A     T  +  N+T    T  A  +T+  ++A+  
Sbjct: 205 QNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPT--ADTQTQNVNQAKMA 262

Query: 264 IAKVINTDTEHIEALNVTDAATRQIEA---------SVVAIRPKKSKGKKAASRGPNSVS 314
            ++    D E    ++  D AT Q  A         S   IR K+++     +   NS  
Sbjct: 263 TSQ---ADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENSSG 319

Query: 315 EISEAPLA 322
           +   APLA
Sbjct: 320 DQRRAPLA 327


>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score =  343 bits (881), Expect = 2e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 463 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 522

Query: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 523 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 582

Query: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 583 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 642

Query: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 643 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 73/267 (27%), Positives = 106/267 (39%), Gaps = 46/267 (17%)

Query: 180 QNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQIT 239
           Q+   P ANE A  Q    + +PK A K + A  K      + S A  A     TQ    
Sbjct: 52  QSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQ---- 107

Query: 240 NETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKK 299
                          K A K++    K  N   +  +A    + A  + E +        
Sbjct: 108 --------------PKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAF------- 146

Query: 300 SKGKKAASR-GPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTP 358
            K + A ++ GPN+    S++  A  +       A  R K   +A    TKA   ++QT 
Sbjct: 147 -KAQNATTKVGPNATYNFSQSLNANDL-------ANSRPKTPFKAWNDTTKAPTADTQTQ 198

Query: 359 NADQGAQAKIASAQTNVS---ALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKH 415
           N +   QAK+A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +
Sbjct: 199 NVN---QAKMATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINN 254

Query: 416 LNGDERSGSNYRRIP-----WGRRPAP 437
           LN +E S  + RR P     W   P P
Sbjct: 255 LNVEENSSGDQRRAPLAAGTWRSAPVP 281



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 78/310 (25%), Positives = 115/310 (37%), Gaps = 73/310 (23%)

Query: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAA 92
           Q E + EDS LLM TL+ A + S A  PP         T +A       A+P +   P A
Sbjct: 15  QAEASVEDSALLMQTLMEAIQISEA--PP---------TNQA----TAAASPQSSQPPTA 59

Query: 93  NEIATNKPKITWQALNLPVITQISQALPTTEVTNTQASSVTAQPKKANKMKRVTAKAAQG 152
           NE+A                             + Q S+  A+PK A K++  T K   G
Sbjct: 60  NEMA-----------------------------DIQVSAAAARPKSAFKVQNATTKGPNG 90

Query: 153 SQS-PTGHEGGTIQLKSPLQVLKLPVISQNI-----HAPIANESASSQALITSIKPKKAS 206
                  H    +    P    K    SQN      +A      A++   + + K + A 
Sbjct: 91  VYDFSQAHNAKDVPNTQPKAAFK----SQNATPKGPNAAYDFSQAATTGELAANKSEMAF 146

Query: 207 KAKKAANKAIASAT---EVSLAAT--ATHTATTQGQITNETASIHTTAASIRTKKASKAR 261
           KA+ A  K   +AT     SL A   A     T  +  N+T    T  A  +T+  ++A+
Sbjct: 147 KAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPT--ADTQTQNVNQAK 204

Query: 262 KTIAKVINTDTEHIEALNVTDAATRQIEA---------SVVAIRPKKSKGKKAASRGPNS 312
              ++    D E    ++  D AT Q  A         S   IR K+++     +   NS
Sbjct: 205 MATSQ---ADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENS 261

Query: 313 VSEISEAPLA 322
             +   APLA
Sbjct: 262 SGDQRRAPLA 271


>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score =  343 bits (881), Expect = 2e-94
 Identities = 166/227 (73%), Positives = 193/227 (85%)

Query: 436 APPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495
           A PRDVA+LQERANKLVKYL++KD TK+PIKRS+MLRD+I+EY + +PEIIERA + LEK
Sbjct: 463 AQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEK 522

Query: 496 MFRVNLKEIDKQSSLYILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVI 555
            F + LKEIDK+  LYILIST ES AGILGTTKDTPKLGLL+VIL VIFMNGN+ASEAV+
Sbjct: 523 KFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGVIFMNGNRASEAVL 582

Query: 556 WEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHET 615
           WE LRK+GLRPGVRH L G++RKL+T EFVKQKYL+Y+RVPNS PPEYEF WGLRSYHET
Sbjct: 583 WEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHET 642

Query: 616 SKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEARAE 662
           SKMKVL+F   VQK+DP+DW  Q+ EA +  + A   A AEAEARAE
Sbjct: 643 SKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAE 689



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 73/267 (27%), Positives = 106/267 (39%), Gaps = 46/267 (17%)

Query: 180 QNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQIT 239
           Q+   P ANE A  Q    + +PK A K + A  K      + S A  A     TQ    
Sbjct: 52  QSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQ---- 107

Query: 240 NETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKK 299
                          K A K++    K  N   +  +A    + A  + E +        
Sbjct: 108 --------------PKAAFKSQNATPKGPNAAYDFSQAATTGELAANKSEMAF------- 146

Query: 300 SKGKKAASR-GPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTP 358
            K + A ++ GPN+    S++  A  +       A  R K   +A    TKA   ++QT 
Sbjct: 147 -KAQNATTKVGPNATYNFSQSLNANDL-------ANSRPKTPFKAWNDTTKAPTADTQTQ 198

Query: 359 NADQGAQAKIASAQTNVS---ALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKH 415
           N +   QAK+A++Q ++     +     A  Q  AD   AQ +LE  T  RGKR RK  +
Sbjct: 199 NVN---QAKMATSQADIETDPGISEPDGATAQTSADGSQAQ-NLESRTIIRGKRTRKINN 254

Query: 416 LNGDERSGSNYRRIP-----WGRRPAP 437
           LN +E S  + RR P     W   P P
Sbjct: 255 LNVEENSSGDQRRAPLAAGTWRSAPVP 281



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 78/310 (25%), Positives = 115/310 (37%), Gaps = 73/310 (23%)

Query: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAA 92
           Q E + EDS LLM TL+ A + S A  PP         T +A       A+P +   P A
Sbjct: 15  QAEASVEDSALLMQTLMEAIQISEA--PP---------TNQA----TAAASPQSSQPPTA 59

Query: 93  NEIATNKPKITWQALNLPVITQISQALPTTEVTNTQASSVTAQPKKANKMKRVTAKAAQG 152
           NE+A                             + Q S+  A+PK A K++  T K   G
Sbjct: 60  NEMA-----------------------------DIQVSAAAARPKSAFKVQNATTKGPNG 90

Query: 153 SQS-PTGHEGGTIQLKSPLQVLKLPVISQNI-----HAPIANESASSQALITSIKPKKAS 206
                  H    +    P    K    SQN      +A      A++   + + K + A 
Sbjct: 91  VYDFSQAHNAKDVPNTQPKAAFK----SQNATPKGPNAAYDFSQAATTGELAANKSEMAF 146

Query: 207 KAKKAANKAIASAT---EVSLAAT--ATHTATTQGQITNETASIHTTAASIRTKKASKAR 261
           KA+ A  K   +AT     SL A   A     T  +  N+T    T  A  +T+  ++A+
Sbjct: 147 KAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTKAPT--ADTQTQNVNQAK 204

Query: 262 KTIAKVINTDTEHIEALNVTDAATRQIEA---------SVVAIRPKKSKGKKAASRGPNS 312
              ++    D E    ++  D AT Q  A         S   IR K+++     +   NS
Sbjct: 205 MATSQ---ADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRTRKINNLNVEENS 261

Query: 313 VSEISEAPLA 322
             +   APLA
Sbjct: 262 SGDQRRAPLA 271


>gi|20162572 necdin-like 2 [Homo sapiens]
          Length = 304

 Score =  204 bits (519), Expect = 2e-52
 Identities = 102/216 (47%), Positives = 150/216 (69%), Gaps = 4/216 (1%)

Query: 438 PRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMF 497
           PR    L+ + ++LV++LL+KDQ KIPIKR+D+L+ VI +Y + FP++ +RA+  L+ +F
Sbjct: 79  PRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAERLQYVF 138

Query: 498 RVNLKEIDKQSSLYILISTQE---SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAV 554
              L E++ +S+ YILI+T E     A + G  + TP  GLLM++L +IFM GN   E  
Sbjct: 139 GYKLVELEPKSNTYILINTLEPVEEDAEMRGD-QGTPTTGLLMIVLGLIFMKGNTIKETE 197

Query: 555 IWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE 614
            W+ LR+LG+ P  +H +FG+ +KLIT++FV+Q+YLEY+R+P++ P +YEF WG R+  E
Sbjct: 198 AWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNLE 257

Query: 615 TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAA 650
           TSKMKVLKF  +V  +DPKDW  QY EA+  E   A
Sbjct: 258 TSKMKVLKFVAKVHNQDPKDWPAQYCEALADEENRA 293


>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
          Length = 307

 Score =  196 bits (498), Expect = 6e-50
 Identities = 108/223 (48%), Positives = 149/223 (66%), Gaps = 7/223 (3%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           L     +LV++LLVKD+ K PI RS+M++ VI +    FP+II RA+  L  +F   LK+
Sbjct: 76  LNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQ 135

Query: 504 IDKQSSLYILIST----QESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVL 559
            D++   YILI+     +E     LG   D P+LGLLM+IL +I+M GN A EA +WE+L
Sbjct: 136 FDRKHHTYILINKLKPLEEEEEEDLGG--DGPRLGLLMMILGLIYMRGNSAREAQVWEML 193

Query: 560 RKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMK 619
           R+LG++P   H LFG  ++LI ++FV+Q+YL Y+RVP++ PPEYEF WG RS  E SKM+
Sbjct: 194 RRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKME 253

Query: 620 VLKFACRVQKKDPKDWAVQYREAVEMEV-QAAAVAVAEAEARA 661
           VL F  ++ KK+P+ W VQYREA+  E  +A A A AEA  RA
Sbjct: 254 VLGFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRA 296


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score =  194 bits (493), Expect = 2e-49
 Identities = 111/281 (39%), Positives = 166/281 (59%), Gaps = 26/281 (9%)

Query: 423 GSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYF 482
           G N  R+    +P  P     +++   +L+++LLVKDQ+K PI+ S+M   +++EY   F
Sbjct: 475 GLNTSRVAITLKPQDP-----MEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQF 529

Query: 483 PEIIERASYTLEKMFRVNLKEIDKQSSLYILIST---------QESSAGILGTTKDTPKL 533
           PEI+ RA+  LE +FR  L+E+D ++  YIL++          +ES  G        PK+
Sbjct: 530 PEILRRAAAHLECIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNG--------PKM 581

Query: 534 GLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYK 593
           GLLM+IL  IF+NGN+A EA IWE+L ++G++   R S+FG  ++L++ EFV Q+YL+Y+
Sbjct: 582 GLLMMILGQIFLNGNQAKEAEIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYR 641

Query: 594 RVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVA 653
            V + +P EYEFFWG RS+ ET+KMK+LKF  ++  KDP DW  +Y EA+E   + AA A
Sbjct: 642 PVTDCKPVEYEFFWGPRSHLETTKMKILKFMAKIYNKDPMDWPEKYNEALE---EDAARA 698

Query: 654 VAEA-EARAEIYSPCLQIPLINCSSPSHGAKVHPWNLCPHS 693
            AE  +A      P  +       SP      +     PHS
Sbjct: 699 FAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHS 739



 Score =  147 bits (371), Expect = 3e-35
 Identities = 78/210 (37%), Positives = 125/210 (59%), Gaps = 9/210 (4%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           L+ +A KLV+  L+ D TK+PI +  +L  + +E  + FP+++ RA+ TL  ++   L  
Sbjct: 745 LESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVV 804

Query: 504 IDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
           +D ++  Y L + +E      +  + + P    LM +LS IF+ GN A E+ +W  LR L
Sbjct: 805 LDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGL 864

Query: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
           G++ G +H        +IT  ++ Q+Y++  RVP+S P +YEF WG R+  ETSKMK L+
Sbjct: 865 GVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALR 916

Query: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAV 652
           +  R+ +K+P+DW  QYREA+E E   A V
Sbjct: 917 YVARIHRKEPQDWPQQYREAMEDEANRADV 946


>gi|148746206 MAGE-like protein 2 [Homo sapiens]
          Length = 646

 Score =  193 bits (491), Expect = 4e-49
 Identities = 99/201 (49%), Positives = 138/201 (68%), Gaps = 1/201 (0%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           L ERAN LV++LLVKDQ K+P++RS+M++ +++EY +   +II RA+  LE  F   LKE
Sbjct: 417 LDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKE 476

Query: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
           ID ++  YI+I+      G ++ +  D PK GLLMV+LS+IFM GN   E +I+  L KL
Sbjct: 477 IDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKL 536

Query: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
           GL     + LFG  +KLIT+ FV+QKYLEY+R+P + P EYEF WG R++ ETSKM VL+
Sbjct: 537 GLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLR 596

Query: 623 FACRVQKKDPKDWAVQYREAV 643
           F  ++ KKDP+ W   Y EA+
Sbjct: 597 FLAKLHKKDPQSWPFHYLEAL 617



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 31/311 (9%)

Query: 123 EVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNI 182
           EV  TQA +  AQ    +  + + A+ AQ    P       +QL+ P Q       +  I
Sbjct: 5   EVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPL------VQLEQPFQGAPPSQKAVQI 58

Query: 183 HAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITNET 242
             P     AS         P + S     A  A+  A      A A     +   +   T
Sbjct: 59  QLPPQQAQASGPQAEVPTLPLQPSWQ---APPAVLQAQPGPPVAAANFPLGSAKSLM--T 113

Query: 243 ASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKSKG 302
            S    A+SI  + +SK R+T +K     ++       T  A + + A+   +       
Sbjct: 114 PSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHL------- 166

Query: 303 KKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNADQ 362
             AA +   +  E      +    T+Q   A+L   +G  A     K+     Q P A  
Sbjct: 167 -PAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACV 225

Query: 363 GAQAKIASA-QTNVSALETQ---------VAAAVQALADDYLA-QLSLEPTTRTRGKRNR 411
            A   +    Q N++A +            AAA QA A    A + S+EP  R+ GK  R
Sbjct: 226 EALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRS-GKATR 284

Query: 412 KSKHLNGDERS 422
           K KHL   E S
Sbjct: 285 KKKHLEAQEDS 295


>gi|4505349 necdin [Homo sapiens]
          Length = 321

 Score =  183 bits (464), Expect = 5e-46
 Identities = 94/211 (44%), Positives = 139/211 (65%), Gaps = 2/211 (0%)

Query: 435 PAPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLE 494
           PAPP    ++Q +A++L+ Y+LVKDQ K+ I   DM++DVI  Y ++   I+ R S  L 
Sbjct: 90  PAPPAPAQLVQ-KAHELMWYVLVKDQKKMIIWFPDMVKDVIGSYKKWCRSILRRTSLILA 148

Query: 495 KMFRVNLKEIDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEA 553
           ++F ++L+     +  + L+   E      +  +   P  GLL++ILS+I++ G  A E+
Sbjct: 149 RVFGLHLRLTSLHTMEFALVKALEPEELDRVALSNRMPMTGLLLMILSLIYVKGRGARES 208

Query: 554 VIWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYH 613
            +W VLR LGLRP  +HS FG+VRKLIT+EFV+  YL+Y+RVP   PPEYEFFWG R+  
Sbjct: 209 AVWNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYLKYQRVPYVEPPEYEFFWGSRASR 268

Query: 614 ETSKMKVLKFACRVQKKDPKDWAVQYREAVE 644
           E +KM++++F  RV KKDP+ W  +YREA+E
Sbjct: 269 EITKMQIMEFLARVFKKDPQAWPSRYREALE 299


>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
          Length = 346

 Score =  183 bits (464), Expect = 5e-46
 Identities = 112/323 (34%), Positives = 166/323 (51%), Gaps = 1/323 (0%)

Query: 339 RGSRAR-KAATKARATESQTPNADQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQL 397
           RG +++ +A  K + T  QT +   G        ++  S+       A  +LA     + 
Sbjct: 3   RGQKSKLRAREKRQRTRGQTQDLKVGQPTAAEKEESPSSSSSVLRDTASSSLAFGIPQEP 62

Query: 398 SLEPTTRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLV 457
             EP T +       +    GDE                       L  +   LV++LL 
Sbjct: 63  QREPPTTSAAAAMSCTGSDKGDESQDEENASSSQASTSTERSLKDSLTRKTKMLVQFLLY 122

Query: 458 KDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQ 517
           K + K P  +++ML+ + ++Y E+FPEI  + S   E +F + LKE++  +  YIL+S  
Sbjct: 123 KYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQRTELVFGLALKEVNPTTHSYILVSML 182

Query: 518 ESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVR 577
             + G   +    P+ GLLM +LSVIF+NGN A E  IWE L  LG+  G RH +FGE R
Sbjct: 183 GPNDGNQSSAWTLPRNGLLMPLLSVIFLNGNCAREEEIWEFLNMLGIYDGKRHLIFGEPR 242

Query: 578 KLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAV 637
           KLIT + V++KYLEY++VPNS PP Y+F WG R++ ETSKMKVL+F  +V    P ++ +
Sbjct: 243 KLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTTPNNFPL 302

Query: 638 QYREAVEMEVQAAAVAVAEAEAR 660
            Y EA+  E + A      A  R
Sbjct: 303 LYEEALRDEEERAGARPRVAARR 325


>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
          Length = 347

 Score =  182 bits (461), Expect = 1e-45
 Identities = 96/218 (44%), Positives = 137/218 (62%), Gaps = 2/218 (0%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           + E+   LV YLL K Q K PI ++DMLR+V Q     FP I+ RAS  LE +F ++LKE
Sbjct: 111 VDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKE 170

Query: 504 IDKQSSLYILISTQESSAGI-LGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
           ++    +Y+L++  +      L      PK GLLM +L +IF NGN  +E  +W+V   +
Sbjct: 171 VEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTM 230

Query: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
           GL  G+ H +FGE RKL+T + VK+ YLEY++VPNS PP Y+F WG R++ ETSKMKVL+
Sbjct: 231 GLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLE 290

Query: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAEAR 660
           F  +V    P +++  Y EA++ E + A   VA A+AR
Sbjct: 291 FLAKVNDTAPSEFSNWYTEALQDEEERARARVA-AKAR 327


>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
          Length = 346

 Score =  179 bits (453), Expect = 1e-44
 Identities = 95/210 (45%), Positives = 137/210 (65%), Gaps = 4/210 (1%)

Query: 447 RANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDK 506
           + N LV++L+   + K PI ++DML+ V + +   FPEI+++AS+ +E +F V+LK++D 
Sbjct: 114 KTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDS 173

Query: 507 QSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLR 565
               Y+L+S  +  + G +   +  PK GLL+ +L VIFM GN A+E  IWE L K+ + 
Sbjct: 174 TKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIY 233

Query: 566 PGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFAC 625
            G +H +FGE RKLIT + VK KYLEY++VPNS P  YEF WG R++ ETSKMKVL+F  
Sbjct: 234 DGKKHFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWA 293

Query: 626 RVQKKDPKDWAVQYREAV---EMEVQAAAV 652
           +V K  P  +   Y EA+   E  VQAAA+
Sbjct: 294 KVNKTVPSAFQFWYEEALRDEEERVQAAAM 323


>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
          Length = 324

 Score =  175 bits (443), Expect = 1e-43
 Identities = 95/220 (43%), Positives = 139/220 (63%), Gaps = 3/220 (1%)

Query: 438 PRDVAI--LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEK 495
           PR+V    L ++   LV ++L K Q K PI ++DML+ +I++ + +F EI+ RAS  LE 
Sbjct: 105 PRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILLRASEHLEM 164

Query: 496 MFRVNLKEIDKQSSLY-ILISTQESSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAV 554
           +F +++ E+D  +  Y + I    +  G+L   K  PK GLL+++L VIFM GN+A+E  
Sbjct: 165 IFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMKGNRATEEE 224

Query: 555 IWEVLRKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHE 614
           +WEVL   G+  G +H +FGE R LIT +FVK+KYLEY++V NS P  YEF WG R+  E
Sbjct: 225 VWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFLWGPRAKAE 284

Query: 615 TSKMKVLKFACRVQKKDPKDWAVQYREAVEMEVQAAAVAV 654
           TSKMKVL+F  +V    P  +  QY EA++ E + A   +
Sbjct: 285 TSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEEERARARI 324


>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  171 bits (434), Expect = 2e-42
 Identities = 114/343 (33%), Positives = 181/343 (52%), Gaps = 25/343 (7%)

Query: 333 ATLRVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSALETQVAAAVQALADD 392
           +T+ + RG  +++ A + R           GAQA  A  +   S+      +  Q+  + 
Sbjct: 118 STVIMPRGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNA 177

Query: 393 YLAQLS------------LEPTTRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRD 440
            + Q S            +  T+   G + +K +  N      S+          +  RD
Sbjct: 178 GIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSFHGPSSS---------ESTGRD 228

Query: 441 VAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVN 500
             +L  +  +LV++LL K   K PI R  ML+ + ++Y ++FPEI+ R++  +E +F + 
Sbjct: 229 --LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLY 286

Query: 501 LKEIDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVL 559
           LKE+D     Y+L+   +  + G L      P  GLLMV+LS IFM+GN+A+E  +WE L
Sbjct: 287 LKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECL 346

Query: 560 RKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMK 619
             LG+  G +H ++GE ++L+T + V++ YLEY++VP+S PP YEF WG R+  ETSKMK
Sbjct: 347 NALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMK 406

Query: 620 VLKFACRVQKKDPKDWAVQYREAV-EMEVQAAAVAVAEAEARA 661
           VL+F  ++       +  +Y EA+ E E QA A AVA   ARA
Sbjct: 407 VLEFVAKLNDTVASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  171 bits (434), Expect = 2e-42
 Identities = 114/343 (33%), Positives = 181/343 (52%), Gaps = 25/343 (7%)

Query: 333 ATLRVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSALETQVAAAVQALADD 392
           +T+ + RG  +++ A + R           GAQA  A  +   S+      +  Q+  + 
Sbjct: 118 STVIMPRGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNA 177

Query: 393 YLAQLS------------LEPTTRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRD 440
            + Q S            +  T+   G + +K +  N      S+          +  RD
Sbjct: 178 GIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSFHGPSSS---------ESTGRD 228

Query: 441 VAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVN 500
             +L  +  +LV++LL K   K PI R  ML+ + ++Y ++FPEI+ R++  +E +F + 
Sbjct: 229 --LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLY 286

Query: 501 LKEIDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVL 559
           LKE+D     Y+L+   +  + G L      P  GLLMV+LS IFM+GN+A+E  +WE L
Sbjct: 287 LKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECL 346

Query: 560 RKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMK 619
             LG+  G +H ++GE ++L+T + V++ YLEY++VP+S PP YEF WG R+  ETSKMK
Sbjct: 347 NALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMK 406

Query: 620 VLKFACRVQKKDPKDWAVQYREAV-EMEVQAAAVAVAEAEARA 661
           VL+F  ++       +  +Y EA+ E E QA A AVA   ARA
Sbjct: 407 VLEFVAKLNDTVASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  171 bits (434), Expect = 2e-42
 Identities = 114/343 (33%), Positives = 181/343 (52%), Gaps = 25/343 (7%)

Query: 333 ATLRVKRGSRARKAATKARATESQTPNADQGAQAKIASAQTNVSALETQVAAAVQALADD 392
           +T+ + RG  +++ A + R           GAQA  A  +   S+      +  Q+  + 
Sbjct: 118 STVIMPRGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNA 177

Query: 393 YLAQLS------------LEPTTRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRD 440
            + Q S            +  T+   G + +K +  N      S+          +  RD
Sbjct: 178 GIPQESQRASYPSSPASAVSLTSSDEGAKGQKGESPNSFHGPSSS---------ESTGRD 228

Query: 441 VAILQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVN 500
             +L  +  +LV++LL K   K PI R  ML+ + ++Y ++FPEI+ R++  +E +F + 
Sbjct: 229 --LLNTKTGELVQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLY 286

Query: 501 LKEIDKQSSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVL 559
           LKE+D     Y+L+   +  + G L      P  GLLMV+LS IFM+GN+A+E  +WE L
Sbjct: 287 LKEMDPSRQSYVLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECL 346

Query: 560 RKLGLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMK 619
             LG+  G +H ++GE ++L+T + V++ YLEY++VP+S PP YEF WG R+  ETSKMK
Sbjct: 347 NALGMYKGRKHFIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMK 406

Query: 620 VLKFACRVQKKDPKDWAVQYREAV-EMEVQAAAVAVAEAEARA 661
           VL+F  ++       +  +Y EA+ E E QA A AVA   ARA
Sbjct: 407 VLEFVAKLNDTVASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
          Length = 343

 Score =  169 bits (429), Expect = 6e-42
 Identities = 112/325 (34%), Positives = 166/325 (51%), Gaps = 25/325 (7%)

Query: 347 ATKARATESQTPNADQGAQAKIASAQTNVSALETQVAAAVQALADDYLAQLSLEPTTRTR 406
           AT+A   E ++P++   A         N+ A ET         A      ++    +   
Sbjct: 27  ATQATVAEGESPSS---AYLLFGDRPQNLPAAETPSIPEALQGAPSTTNAIAPVSCSSNE 83

Query: 407 GKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTKIPIK 466
           G  ++  K L G  R    ++  P             L ++   LV +LL K +TK PI 
Sbjct: 84  GASSQDEKSL-GSSREAEGWKEDP-------------LNKKVVSLVHFLLQKYETKEPIT 129

Query: 467 RSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQESSAGILGT 526
           + DM++ VI++   +F EI++RAS  +E    V+LKE+D     Y   S  + +     T
Sbjct: 130 KGDMIKFVIRKDKCHFNEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYD--ET 187

Query: 527 TKDT---PKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLITDE 583
           T D    PK GLLM+ L VIF+NGN+A E  +WE++  +G+    +H L+G+ RK++T +
Sbjct: 188 TSDEEKIPKTGLLMIALGVIFLNGNRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKD 247

Query: 584 FVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYREAV 643
            V+ KYLEY++VPNS PP YEF WG R++ ETSKMKVL+F  ++    P  +   Y EA+
Sbjct: 248 LVQLKYLEYQQVPNSDPPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEAL 307

Query: 644 ---EMEVQAAAVAVAEAEARAEIYS 665
              E   QA A A A   A A   S
Sbjct: 308 RDEEQRTQARAAARAHTAAMANARS 332


>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (425), Expect = 2e-41
 Identities = 81/216 (37%), Positives = 136/216 (62%), Gaps = 1/216 (0%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           + E+   LV++LL K Q K PI ++++L  VI+ Y+++FP +   AS  +  +F +++KE
Sbjct: 134 IDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKE 193

Query: 504 IDKQSSLYILISTQESSA-GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
           +D     ++L+++   +  G+L   +  PK G+L++ILS+IF+ G    E VIWE L  +
Sbjct: 194 VDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMM 253

Query: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
           GL  G+ H ++GE RKL+T ++V++ YLEY++VP S P  YEF WG R++ E  KM +LK
Sbjct: 254 GLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLK 313

Query: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAE 658
           F  +V   DP+ + + Y EA++ E + A   +A  +
Sbjct: 314 FLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTD 349


>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  168 bits (425), Expect = 2e-41
 Identities = 81/216 (37%), Positives = 136/216 (62%), Gaps = 1/216 (0%)

Query: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
           + E+   LV++LL K Q K PI ++++L  VI+ Y+++FP +   AS  +  +F +++KE
Sbjct: 134 IDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYEDHFPLLFSEASECMLLVFGIDVKE 193

Query: 504 IDKQSSLYILISTQESSA-GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
           +D     ++L+++   +  G+L   +  PK G+L++ILS+IF+ G    E VIWE L  +
Sbjct: 194 VDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIIFIEGYCTPEEVIWEALNMM 253

Query: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
           GL  G+ H ++GE RKL+T ++V++ YLEY++VP S P  YEF WG R++ E  KM +LK
Sbjct: 254 GLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLK 313

Query: 623 FACRVQKKDPKDWAVQYREAVEMEVQAAAVAVAEAE 658
           F  +V   DP+ + + Y EA++ E + A   +A  +
Sbjct: 314 FLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTD 349


>gi|29171711 melanoma antigen family B, 1 [Homo sapiens]
          Length = 347

 Score =  166 bits (419), Expect = 9e-41
 Identities = 86/206 (41%), Positives = 130/206 (63%), Gaps = 1/206 (0%)

Query: 448 ANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQ 507
           A  L+ ++L K + + PI ++DML+ V ++Y ++F EI+  AS  LE +F ++LKE +  
Sbjct: 112 AGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPS 171

Query: 508 SSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRP 566
              Y L+S    ++ G L    D P+ GLLM +L VIF+ GN A+E  IW+ +  LG   
Sbjct: 172 GHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYD 231

Query: 567 GVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACR 626
           G  H ++GE RK IT + V++KYL+Y++VPNS PP Y+F WG R+Y ET+KMKVL+F  +
Sbjct: 232 GEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAK 291

Query: 627 VQKKDPKDWAVQYREAVEMEVQAAAV 652
           +    P+D+   Y EA+  E + A V
Sbjct: 292 MNGATPRDFPSHYEEALRDEEERAQV 317


>gi|29171709 melanoma antigen family B, 1 [Homo sapiens]
          Length = 347

 Score =  166 bits (419), Expect = 9e-41
 Identities = 86/206 (41%), Positives = 130/206 (63%), Gaps = 1/206 (0%)

Query: 448 ANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQ 507
           A  L+ ++L K + + PI ++DML+ V ++Y ++F EI+  AS  LE +F ++LKE +  
Sbjct: 112 AGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPS 171

Query: 508 SSLYILISTQE-SSAGILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRP 566
              Y L+S    ++ G L    D P+ GLLM +L VIF+ GN A+E  IW+ +  LG   
Sbjct: 172 GHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYD 231

Query: 567 GVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACR 626
           G  H ++GE RK IT + V++KYL+Y++VPNS PP Y+F WG R+Y ET+KMKVL+F  +
Sbjct: 232 GEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAK 291

Query: 627 VQKKDPKDWAVQYREAVEMEVQAAAV 652
           +    P+D+   Y EA+  E + A V
Sbjct: 292 MNGATPRDFPSHYEEALRDEEERAQV 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.125    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,400,455
Number of Sequences: 37866
Number of extensions: 1035651
Number of successful extensions: 5167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 178
Number of HSP's that attempted gapping in prelim test: 4406
Number of HSP's gapped (non-prelim): 713
length of query: 706
length of database: 18,247,518
effective HSP length: 109
effective length of query: 597
effective length of database: 14,120,124
effective search space: 8429714028
effective search space used: 8429714028
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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