Guide to the Human Genome
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Search of human proteins with 122937347

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937347 pleckstrin homology domain containing, family M,
member 3 [Homo sapiens]
         (761 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937347 pleckstrin homology domain containing, family M, me...  1551   0.0  
gi|40538728 pleckstrin homology domain containing, family M (wit...   264   3e-70
gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ...   244   2e-64
gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo s...   178   2e-44
gi|239756837 PREDICTED: similar to pleckstrin homology domain co...   173   6e-43
gi|156151402 hypothetical protein LOC80183 [Homo sapiens]             161   2e-39
gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]    150   3e-36
gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]    150   3e-36
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]        52   2e-06
gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]       52   2e-06
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit...    48   4e-05
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom...    40   0.008
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo...    40   0.008
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho...    40   0.008
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho...    40   0.008
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom...    40   0.008
gi|154354979 myosin X [Homo sapiens]                                   35   0.20 
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform...    35   0.34 
gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]      35   0.34 
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H...    34   0.58 
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H...    34   0.58 
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]             33   0.76 
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]             33   0.76 
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H...    33   1.3  
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H...    33   1.3  
gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]           32   1.7  
gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]            32   1.7  
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa...    32   2.2  
gi|4759158 small nuclear ribonucleoprotein D2 isoform 1 [Homo sa...    31   3.7  
gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long ...    31   4.9  

>gi|122937347 pleckstrin homology domain containing, family M,
           member 3 [Homo sapiens]
          Length = 761

 Score = 1551 bits (4017), Expect = 0.0
 Identities = 761/761 (100%), Positives = 761/761 (100%)

Query: 1   MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAM 60
           MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAM
Sbjct: 1   MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAM 60

Query: 61  RNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFF 120
           RNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFF
Sbjct: 61  RNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFF 120

Query: 121 NICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQG 180
           NICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQG
Sbjct: 121 NICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQG 180

Query: 181 PHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNL 240
           PHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNL
Sbjct: 181 PHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNL 240

Query: 241 YFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWG 300
           YFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWG
Sbjct: 241 YFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWG 300

Query: 301 QKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ 360
           QKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ
Sbjct: 301 QKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ 360

Query: 361 NILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDG 420
           NILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDG
Sbjct: 361 NILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDG 420

Query: 421 CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGH 480
           CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGH
Sbjct: 421 CDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGH 480

Query: 481 ELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCS 540
           ELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCS
Sbjct: 481 ELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCS 540

Query: 541 SCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAA 600
           SCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAA
Sbjct: 541 SCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAA 600

Query: 601 VLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFL 660
           VLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFL
Sbjct: 601 VLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFL 660

Query: 661 GKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSV 720
           GKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSV
Sbjct: 661 GKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSV 720

Query: 721 PCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT 761
           PCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT
Sbjct: 721 PCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT 761


>gi|40538728 pleckstrin homology domain containing, family M (with RUN
            domain) member 1 [Homo sapiens]
          Length = 1056

 Score =  264 bits (674), Expect = 3e-70
 Identities = 176/545 (32%), Positives = 275/545 (50%), Gaps = 37/545 (6%)

Query: 209  FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268
            F  ++K G +E R+     W+  + ELSP     Y   S+          L   +S+   
Sbjct: 532  FRGLMKLGTVE-RRGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 587

Query: 269  GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328
             + + R    +++   +L L+A S  EA DW  ++ E +    P    +Q +  ++    
Sbjct: 588  AHSDGRF--ELVFSGKKLALRASSQDEAEDWLDRVREALQKVRP----QQEDEWVNV--- 638

Query: 329  HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374
             + D  Q     +   G L PS +L      Q              + +K   LY L + 
Sbjct: 639  QYPD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLY-LYMD 695

Query: 375  NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434
              W  + F LS   L  F+    ++    S+ V+    +  D   G  S F++I  + VL
Sbjct: 696  RTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 755

Query: 435  RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493
            +L+A   + A  W + + K+ A+   ++E+   VTL     D+     L+   R++    
Sbjct: 756  KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 810

Query: 494  FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553
             L  L  + +E+GL +Q   CAGC R IG S  + K+C +SG YYC  CH DD+ +IPAR
Sbjct: 811  LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 870

Query: 554  IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613
            I+HNWD +K  + +QA +FL  +  +PLI++Q  NA LY H E +  + R R++LK L  
Sbjct: 871  IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 930

Query: 614  YLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYS 673
            YL  CR+   ++L +R+  R YLL+  H +S+ADLQQ+ +G    FL  +I+FA+ HVY 
Sbjct: 931  YLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYH 990

Query: 674  CSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSVPCPRCVRRELQK 732
            C LC+Q+GFIC+IC + +I++PFE  +T RC  C  VFH  C+      CPRC RR   +
Sbjct: 991  CDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKYQ 1050

Query: 733  KQKSF 737
            +Q  F
Sbjct: 1051 EQNIF 1055


>gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
           sapiens]
          Length = 528

 Score =  244 bits (623), Expect = 2e-64
 Identities = 167/535 (31%), Positives = 265/535 (49%), Gaps = 37/535 (6%)

Query: 209 FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268
           F  ++K G +E R+     W+  + ELSP     Y   S+          L   +S+   
Sbjct: 15  FQGLMKLGTVE-RQGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 70

Query: 269 GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328
            + + R    +++   +L L+A S  EA DW     ++V  A+     +Q +  ++    
Sbjct: 71  AHSDGRF--ELVFSGKKLALRASSQDEAEDW----LDLVREALQKVRPQQEDEWVNV--- 121

Query: 329 HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374
            + D  Q     +   G L PS +L      Q              + +K   LY L + 
Sbjct: 122 QYSD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLY-LYMD 178

Query: 375 NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434
             W  + F L    L  F+    ++    S+ V+    +  D   G  S F++I  + VL
Sbjct: 179 RTWMPYIFSLPLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 238

Query: 435 RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493
           +L+A   + A  W + + K+ A+   ++E+   VTL     D+     L+   R++    
Sbjct: 239 KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 293

Query: 494 FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553
            L  L  + +E+GL +Q   CAGC R IG S  + K+C +SG YYC  CH DD+ +IPAR
Sbjct: 294 LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 353

Query: 554 IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613
           I+HNWD +K  + +QA +FL  +  +PLI++Q  NA LY H E +  + R R++LK L  
Sbjct: 354 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGD 413

Query: 614 YLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYS 673
           YL  CR+   ++L +R+  R YLL+  H + +ADL+Q+ +     FL  +I+FA+ HVY 
Sbjct: 414 YLGLCRSGALKELSKRLNHRNYLLESPHRFRVADLRQIADEVYEGFLKALIEFASQHVYH 473

Query: 674 CSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSVPCPRCVR 727
           C LC+Q+ FIC+IC + +I++P E  +T RC  C  VFH  C+      CPRC R
Sbjct: 474 CDLCTQRSFICQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 14/128 (10%)

Query: 347 LPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLS----RAYLMAFQPGKLDEDPL 402
           LP  P L  S  +Q ++K GT+ R      WK     LS    R YL   +   ++   L
Sbjct: 5   LPLPPGL--SNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSL 62

Query: 403 LSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSE 462
           L      C +V   + DG    F+++F    L LRA ++  A++W++ ++ A    R  +
Sbjct: 63  LR-----CESVGPAHSDG---RFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQ 114

Query: 463 QNLQVTLR 470
           ++  V ++
Sbjct: 115 EDEWVNVQ 122


>gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo
           sapiens]
          Length = 512

 Score =  178 bits (451), Expect = 2e-44
 Identities = 85/234 (36%), Positives = 137/234 (58%), Gaps = 5/234 (2%)

Query: 504 ERGLTAQSFKCAGCQRSIGLSN--GKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTS 561
           E GL +Q ++CA C+  I L     +A+ C+Y+G YYCS CH +D  +IPAR+VHNWD  
Sbjct: 268 ETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFE 327

Query: 562 KYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAA 621
             KVS+ +  +L  +   P++ +++ N +L+ + E L  + +LRQ +  ++ Y  +CR A
Sbjct: 328 PRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREA 387

Query: 622 VAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHV-YSCSLCSQK 680
           +   L  ++  R++ ++   +YS+ DL  V  G+L   L ++      H+   C  C  K
Sbjct: 388 MEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAK 447

Query: 681 GFICEICNNGEILYPFEDISTSRCESCGAVFHSEC-KEKSVPCPRCVRRELQKK 733
           GF+CE+C  G++L+PF D  TS C  C AVFH +C  + S  CP+C R  L+K+
Sbjct: 448 GFVCELCREGDVLFPF-DSHTSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQ 500


>gi|239756837 PREDICTED: similar to pleckstrin homology domain
           containing, family M (with RUN domain) member 1, partial
           [Homo sapiens]
          Length = 623

 Score =  173 bits (438), Expect = 6e-43
 Identities = 155/557 (27%), Positives = 243/557 (43%), Gaps = 60/557 (10%)

Query: 209 FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268
           F  ++K G +E R+     W+  + ELSP     Y   S+          L   +S+   
Sbjct: 98  FRGLMKLGTVE-RRGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 153

Query: 269 GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328
            + + R    +++   +L L+A S  EA DW     ++V  A+     +Q +  ++    
Sbjct: 154 AHSDGRF--ELVFSGKKLALRASSQDEAEDW----LDLVREALQKVRPQQEDEWVNV--- 204

Query: 329 HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374
            + D  Q     +   G L PS +L      Q              + +K   LY L + 
Sbjct: 205 QYSD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEPDAIKESLLY-LYMD 261

Query: 375 NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434
             W  + F LS   L  F+    ++    S+ V+    +  D   G  S F++I  + VL
Sbjct: 262 RTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 321

Query: 435 RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493
           +L+A   + A  W + + K+ A+   ++E+   VTL     D+     L+   R++    
Sbjct: 322 KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 376

Query: 494 FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553
            L  L  + +E+GL +Q   CAGC R IG S  + K+C +SG YYC  CH DD+ +IPAR
Sbjct: 377 LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 436

Query: 554 IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613
           I+HNWD +K  + +QA +FL  +  +PLI++Q  NA LY H E +  + R R++LK L  
Sbjct: 437 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 496

Query: 614 YLFSCRAAVAEDLRRRIFPREYLLQQIH------------LYSLADLQQVIEGKLAPFLG 661
           YL  CR+   ++L +R  P    L+               L +   L+QV  G      G
Sbjct: 497 YLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRARVCLEQVPRGS----QG 552

Query: 662 KVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSV 720
            V    +    S SL  + G     C     +    D     C  C  VFH  C+     
Sbjct: 553 VVKSLGSGGALSPSLVKEPG----TCTG---MQTCVDQMPVGCAECKTVFHQSCQAVVKK 605

Query: 721 PCPRCVRRELQKKQKSF 737
            CPRC RR   ++Q  F
Sbjct: 606 GCPRCARRRKYQEQNIF 622


>gi|156151402 hypothetical protein LOC80183 [Homo sapiens]
          Length = 662

 Score =  161 bits (407), Expect = 2e-39
 Identities = 92/278 (33%), Positives = 145/278 (52%), Gaps = 6/278 (2%)

Query: 457 VARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAG 516
           V +  E ++ V    K K ++ G E     R  +     +I   L  +  + AQ+F CAG
Sbjct: 380 VRKDFESSMNVVQEIKFKSRIRGTEDWAPPRFQI---IFNIHPPLKRDLVVAAQNFFCAG 436

Query: 517 CQRSIGLSNGKA-KVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEY 575
           C   +     K  + C Y G Y+C  CH      IPARI+  WD  KY VS  +K+ L+ 
Sbjct: 437 CGTPVEPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDS 496

Query: 576 VYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREY 635
           ++ +P+ ++      LY  A+ L  V  ++++L  ++  L +CR A +        P  +
Sbjct: 497 IWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPG-H 555

Query: 636 LLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYP 695
           L  ++HL+SL DL ++ +G LAP L  ++K + +HV  C LC  KGFICE C N  +++P
Sbjct: 556 LTDELHLFSLEDLVRIKKGLLAPLLKDILKASLAHVAGCELCQGKGFICEFCQNTTVIFP 615

Query: 696 FEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKK 733
           F+  +  RC +C A FH +C + S  CPRC R   ++K
Sbjct: 616 FQTATCRRCSACRACFHKQCFQSS-ECPRCARITARRK 652


>gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens]
          Length = 927

 Score =  150 bits (380), Expect = 3e-36
 Identities = 83/226 (36%), Positives = 124/226 (54%), Gaps = 4/226 (1%)

Query: 510 QSFKCAGCQ-RSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQ 568
           Q+++CAGC  R+      + + C Y G Y+C  CH +    IP+R++  WD SKY VS  
Sbjct: 672 QNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNF 731

Query: 569 AKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRR 628
           +K+ L  ++ +PL ++Q  N+ LY   + L  V  LR +L  ++    +CR A  E L  
Sbjct: 732 SKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLA-KELLDS 790

Query: 629 RIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEIC- 687
                 +L + +HLYSL DL    +G+L P L ++ +   +HV  C LC  KGFICE C 
Sbjct: 791 FDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQ 850

Query: 688 NNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKK 733
           N  +I++PFE      CE C A +H  C  KS  CPRC R + +++
Sbjct: 851 NEDDIIFPFELHKCRTCEECKACYHKAC-FKSGSCPRCERLQARRE 895


>gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens]
          Length = 972

 Score =  150 bits (380), Expect = 3e-36
 Identities = 83/226 (36%), Positives = 124/226 (54%), Gaps = 4/226 (1%)

Query: 510 QSFKCAGCQ-RSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQ 568
           Q+++CAGC  R+      + + C Y G Y+C  CH +    IP+R++  WD SKY VS  
Sbjct: 717 QNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNF 776

Query: 569 AKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRR 628
           +K+ L  ++ +PL ++Q  N+ LY   + L  V  LR +L  ++    +CR A  E L  
Sbjct: 777 SKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLA-KELLDS 835

Query: 629 RIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEIC- 687
                 +L + +HLYSL DL    +G+L P L ++ +   +HV  C LC  KGFICE C 
Sbjct: 836 FDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQ 895

Query: 688 NNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKK 733
           N  +I++PFE      CE C A +H  C  KS  CPRC R + +++
Sbjct: 896 NEDDIIFPFELHKCRTCEECKACYHKAC-FKSGSCPRCERLQARRE 940


>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
          Length = 1047

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 8/120 (6%)

Query: 359 YQNILKSGTLYRLTVQNNWKAFTFVL--SRAYLMAFQPGKLDEDPLLSYNVDVC-LAVQM 415
           Y+NI+K G L +      WK   F+L  S A L+ F+  K    P    ++ VC + V  
Sbjct: 472 YKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVH 531

Query: 416 DNLDGCDSCFQVI---FPQD--VLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLR 470
           D+L G  +CFQ++   F ++  +     ET ++A++WM+ L+   N+ +SS       LR
Sbjct: 532 DSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLR 591


>gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]
          Length = 870

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 8/120 (6%)

Query: 359 YQNILKSGTLYRLTVQNNWKAFTFVL--SRAYLMAFQPGKLDEDPLLSYNVDVC-LAVQM 415
           Y+NI+K G L +      WK   F+L  S A L+ F+  K    P    ++ VC + V  
Sbjct: 295 YKNIVKKGYLLKKGKGKRWKNLYFILEGSDAQLIYFESEKRATKPKGLIDLSVCSVYVVH 354

Query: 416 DNLDGCDSCFQVI---FPQD--VLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLR 470
           D+L G  +CFQ++   F ++  +     ET ++A++WM+ L+   N+ +SS       LR
Sbjct: 355 DSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKRLR 414


>gi|158631203 dual adaptor of phosphotyrosine and
           3-phosphoinositides [Homo sapiens]
          Length = 280

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 8/127 (6%)

Query: 346 LLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSY 405
           L+P +P L + + Y  + K G L +      WK   F L R  L  F+  ++  +P+   
Sbjct: 157 LVPTAPSLGTKEGY--LTKQGGLVK-----TWKTRWFTLHRNELKYFKD-QMSPEPIRIL 208

Query: 406 NVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNL 465
           ++  C AVQ D      +CF ++FP     L A+T   A EW++ L+   +  R      
Sbjct: 209 DLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQG 268

Query: 466 QVTLRNK 472
           + T+R++
Sbjct: 269 EGTIRSR 275


>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 36/209 (17%)

Query: 4   LEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNV 63
           ++ +D++P +EVT E  S+      K+V   +    Q +      E +SNI  NG+  + 
Sbjct: 526 IKSEDVTP-MEVTAEKRSSTIFKTTKSVGSTQ----QTL------ENISNIAGNGSFSSP 574

Query: 64  TSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNIC 123
           +S         H  S             K+Q +  +   P+ L+ ++ ++ S    F   
Sbjct: 575 SS--------SHLPSE----------NEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAV 616

Query: 124 QRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVV--LKTTPLQQQQQQQPLLQGP 181
                 P S + LL + + F+    +SR +I Q D  VV   + T   QQQQQ PL +  
Sbjct: 617 SASSQLPNS-DALLQQATQFQTRETQSR-EILQSDGTVVNLSQLTEASQQQQQSPLQEQA 674

Query: 182 HVTRP---SFLLPSPNKIEDAQGNTEHKQ 207
              +    S + PSPN +   Q   +  Q
Sbjct: 675 QTLQQQISSNIFPSPNSVSQLQNTIQQLQ 703


>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
           sapiens]
          Length = 1531

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 36/209 (17%)

Query: 4   LEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNV 63
           ++ +D++P +EVT E  S+      K+V   +    Q +      E +SNI  NG+  + 
Sbjct: 602 IKSEDVTP-MEVTAEKRSSTIFKTTKSVGSTQ----QTL------ENISNIAGNGSFSSP 650

Query: 64  TSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNIC 123
           +S         H  S             K+Q +  +   P+ L+ ++ ++ S    F   
Sbjct: 651 SS--------SHLPSE----------NEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAV 692

Query: 124 QRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVV--LKTTPLQQQQQQQPLLQGP 181
                 P S + LL + + F+    +SR +I Q D  VV   + T   QQQQQ PL +  
Sbjct: 693 SASSQLPNS-DALLQQATQFQTRETQSR-EILQSDGTVVNLSQLTEASQQQQQSPLQEQA 750

Query: 182 HVTRP---SFLLPSPNKIEDAQGNTEHKQ 207
              +    S + PSPN +   Q   +  Q
Sbjct: 751 QTLQQQISSNIFPSPNSVSQLQNTIQQLQ 779


>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
           sapiens]
          Length = 1548

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 36/209 (17%)

Query: 4   LEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNV 63
           ++ +D++P +EVT E  S+      K+V   +    Q +      E +SNI  NG+  + 
Sbjct: 619 IKSEDVTP-MEVTAEKRSSTIFKTTKSVGSTQ----QTL------ENISNIAGNGSFSSP 667

Query: 64  TSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNIC 123
           +S         H  S             K+Q +  +   P+ L+ ++ ++ S    F   
Sbjct: 668 SS--------SHLPSE----------NEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAV 709

Query: 124 QRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVV--LKTTPLQQQQQQQPLLQGP 181
                 P S + LL + + F+    +SR +I Q D  VV   + T   QQQQQ PL +  
Sbjct: 710 SASSQLPNS-DALLQQATQFQTRETQSR-EILQSDGTVVNLSQLTEASQQQQQSPLQEQA 767

Query: 182 HVTRP---SFLLPSPNKIEDAQGNTEHKQ 207
              +    S + PSPN +   Q   +  Q
Sbjct: 768 QTLQQQISSNIFPSPNSVSQLQNTIQQLQ 796


>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
           sapiens]
          Length = 1549

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 36/209 (17%)

Query: 4   LEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNV 63
           ++ +D++P +EVT E  S+      K+V   +    Q +      E +SNI  NG+  + 
Sbjct: 620 IKSEDVTP-MEVTAEKRSSTIFKTTKSVGSTQ----QTL------ENISNIAGNGSFSSP 668

Query: 64  TSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNIC 123
           +S         H  S             K+Q +  +   P+ L+ ++ ++ S    F   
Sbjct: 669 SS--------SHLPSE----------NEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAV 710

Query: 124 QRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVV--LKTTPLQQQQQQQPLLQGP 181
                 P S + LL + + F+    +SR +I Q D  VV   + T   QQQQQ PL +  
Sbjct: 711 SASSQLPNS-DALLQQATQFQTRETQSR-EILQSDGTVVNLSQLTEASQQQQQSPLQEQA 768

Query: 182 HVTRP---SFLLPSPNKIEDAQGNTEHKQ 207
              +    S + PSPN +   Q   +  Q
Sbjct: 769 QTLQQQISSNIFPSPNSVSQLQNTIQQLQ 797


>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 36/209 (17%)

Query: 4   LEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNV 63
           ++ +D++P +EVT E  S+      K+V   +    Q +      E +SNI  NG+  + 
Sbjct: 526 IKSEDVTP-MEVTAEKRSSTIFKTTKSVGSTQ----QTL------ENISNIAGNGSFSSP 574

Query: 64  TSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNIC 123
           +S         H  S             K+Q +  +   P+ L+ ++ ++ S    F   
Sbjct: 575 SS--------SHLPSE----------NEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAV 616

Query: 124 QRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVV--LKTTPLQQQQQQQPLLQGP 181
                 P S + LL + + F+    +SR +I Q D  VV   + T   QQQQQ PL +  
Sbjct: 617 SASSQLPNS-DALLQQATQFQTRETQSR-EILQSDGTVVNLSQLTEASQQQQQSPLQEQA 674

Query: 182 HVTRP---SFLLPSPNKIEDAQGNTEHKQ 207
              +    S + PSPN +   Q   +  Q
Sbjct: 675 QTLQQQISSNIFPSPNSVSQLQNTIQQLQ 703


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 12/113 (10%)

Query: 360  QNILKSGTLYR------LTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAV 413
            Q  LK G L++         + NWK   FVL ++ LM F+    D +  L   V+V  A 
Sbjct: 1211 QEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFEN---DSEEKLKGTVEVRTAK 1267

Query: 414  QMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQ 466
            ++ +    ++   +I       L AE+ + A +W   L   + V  S++Q +Q
Sbjct: 1268 EIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVL---SQVHASTDQEIQ 1317


>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
            [Homo sapiens]
          Length = 1045

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 7/111 (6%)

Query: 352  VLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGK----LDEDPLLSYNV 407
            ++D S   +N L    L +    N W+    V +   L  ++  +    L   PLL Y++
Sbjct: 924  MVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSL 983

Query: 408  DVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVA 458
             +    + +N+   D  F++ F   V   RAE+    + WME ++ A + A
Sbjct: 984  TI--PSESENIQK-DYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSA 1031


>gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]
          Length = 359

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)

Query: 207 QTFPNILKKGYLEIRKDHDSY----WQSCYAELSPYNLYFYSLDSSGNQN---LYATYQL 259
           Q  P +LK GYLE R+   S+    WQ  +  LS    Y+Y  D    Q        Y +
Sbjct: 112 QDLPFVLKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSV 171

Query: 260 SHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKL 303
               ++   G  +    +    D    Q  A SP +A +W Q+L
Sbjct: 172 RMNNTLRKDGKKDC-CFEISAPDKRIYQFTAASPKDAEEWVQQL 214


>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
           sapiens]
          Length = 1379

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 17/93 (18%)

Query: 680 KGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVP--------CPRCVRRELQ 731
           + ++C +C+ G+     ED     C+ C   +H  C    +P        CP+CV  E +
Sbjct: 256 ESYVCRMCSRGD-----EDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECK 310

Query: 732 KKQKSF-WQRLNMDESLE---EACTMFELSYQN 760
           +  ++F +++   + +L+   E    F+  Y N
Sbjct: 311 RPPEAFGFEQATREYTLQSFGEMADSFKADYFN 343


>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
           sapiens]
          Length = 1560

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 17/93 (18%)

Query: 680 KGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVP--------CPRCVRRELQ 731
           + ++C +C+ G+     ED     C+ C   +H  C    +P        CP+CV  E +
Sbjct: 323 ESYVCRMCSRGD-----EDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECK 377

Query: 732 KKQKSF-WQRLNMDESLE---EACTMFELSYQN 760
           +  ++F +++   + +L+   E    F+  Y N
Sbjct: 378 RPPEAFGFEQATREYTLQSFGEMADSFKADYFN 410


>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
          Length = 634

 Score = 33.5 bits (75), Expect = 0.76
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 18/64 (28%)

Query: 684 CEICN-NGEILYPFEDISTSRCESCGAVFHSECKE---KSVP-----CPRCVRRELQKKQ 734
           C +C  +G++L          C++C  V+H +C +   K++P     CPRC  + L+K++
Sbjct: 445 CSVCRKSGQLLM---------CDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEE 495

Query: 735 KSFW 738
              W
Sbjct: 496 AIPW 499


>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
          Length = 680

 Score = 33.5 bits (75), Expect = 0.76
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 18/64 (28%)

Query: 684 CEICN-NGEILYPFEDISTSRCESCGAVFHSECKE---KSVP-----CPRCVRRELQKKQ 734
           C +C  +G++L          C++C  V+H +C +   K++P     CPRC  + L+K++
Sbjct: 491 CSVCRKSGQLLM---------CDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEE 541

Query: 735 KSFW 738
              W
Sbjct: 542 AIPW 545


>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
           sapiens]
          Length = 358

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 14/103 (13%)

Query: 207 QTFPNILKKGYLEIR-KDHD---SYWQSCYAELSPYNLYFYSLDSSGNQ------NLYAT 256
           Q   N++K+GYLE + KDH    S WQ  +  +S    Y+Y+ + S           Y  
Sbjct: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162

Query: 257 YQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDW 299
               H +  S     +    +    D    +  A SP EA DW
Sbjct: 163 RMAPHLRRDS----KKESCFELTSQDRRSYEFTATSPAEARDW 201


>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 14/103 (13%)

Query: 207 QTFPNILKKGYLEIR-KDHD---SYWQSCYAELSPYNLYFYSLDSSGNQ------NLYAT 256
           Q   N++K+GYLE + KDH    S WQ  +  +S    Y+Y+ + S           Y  
Sbjct: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162

Query: 257 YQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDW 299
               H +  S     +    +    D    +  A SP EA DW
Sbjct: 163 RMAPHLRRDS----KKESCFELTSQDRRSYEFTATSPAEARDW 201


>gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]
          Length = 489

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 16/63 (25%)

Query: 684 CEICNNGEILYPFEDISTSRCESCGAVFHSECKE---KSVP-----CPRCVRRELQKKQK 735
           C  C  G  L P        C +C   +H  C E   K+ P     CPRC ++ L+K + 
Sbjct: 313 CAACKRGANLQP--------CGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEG 364

Query: 736 SFW 738
             W
Sbjct: 365 VPW 367


>gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]
          Length = 531

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 16/63 (25%)

Query: 684 CEICNNGEILYPFEDISTSRCESCGAVFHSECKE---KSVP-----CPRCVRRELQKKQK 735
           C  C  G  L P        C +C   +H  C E   K+ P     CPRC ++ L+K + 
Sbjct: 355 CAACKRGANLQP--------CGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEG 406

Query: 736 SFW 738
             W
Sbjct: 407 VPW 409


>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
            sapiens]
          Length = 1054

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 11/111 (9%)

Query: 354  DSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDED----PLLSYNVDV 409
            D S   +N L    L +    + W+    V +   L  ++  + D      PLL Y+V +
Sbjct: 923  DHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSI 982

Query: 410  CLAVQMDNLDGC--DSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVA 458
                     DG   D  F++ F   V   RAE++   + WME ++ A++ A
Sbjct: 983  -----PREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEVIQGASSSA 1028


>gi|4759158 small nuclear ribonucleoprotein D2 isoform 1 [Homo
           sapiens]
          Length = 118

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 2/66 (3%)

Query: 467 VTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNG 526
           ++L NKPK +M   EL+K + +   T  LS+LT     +  T     C   ++ +G    
Sbjct: 1   MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLT--QSVKNNTQVLINCRNNKKLLGRVKA 58

Query: 527 KAKVCN 532
             + CN
Sbjct: 59  FDRHCN 64


>gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long B
           isoform [Homo sapiens]
          Length = 537

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 9/62 (14%)

Query: 672 YSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVF--------HSECKEKSVPCP 723
           Y C  C  KGF      NG I          +C++C A F        H  C E  VPC 
Sbjct: 413 YICQSCG-KGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQ 471

Query: 724 RC 725
            C
Sbjct: 472 VC 473


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,082,543
Number of Sequences: 37866
Number of extensions: 1318054
Number of successful extensions: 4262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 4200
Number of HSP's gapped (non-prelim): 79
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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