Guide to the Human Genome
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Search of human proteins with 29171705

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
         (606 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29171705 melanoma antigen family D, 2 [Homo sapiens]              1172   0.0  
gi|19387846 melanoma antigen family D, 2 [Homo sapiens]              1172   0.0  
gi|41350320 melanoma antigen family D, 2 [Homo sapiens]              1172   0.0  
gi|89276766 trophinin isoform 5 [Homo sapiens]                        446   e-125
gi|29540551 trophinin isoform 2 [Homo sapiens]                        395   e-110
gi|29540541 trophinin isoform 2 [Homo sapiens]                        395   e-110
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]     370   e-102
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]     370   e-102
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]     370   e-102
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]    350   3e-96
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    350   3e-96
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]    350   3e-96
gi|149274614 melanoma antigen family D, 4 [Homo sapiens]              350   3e-96
gi|29826296 melanoma antigen family F, 1 [Homo sapiens]               221   1e-57
gi|20162572 necdin-like 2 [Homo sapiens]                              220   3e-57
gi|148746206 MAGE-like protein 2 [Homo sapiens]                       218   1e-56
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]               203   3e-52
gi|4505349 necdin [Homo sapiens]                                      191   2e-48
gi|73623441 melanoma antigen family B, 10 [Homo sapiens]              187   2e-47
gi|4505085 melanoma antigen family B, 4 [Homo sapiens]                184   2e-46
gi|222418639 melanoma antigen family B, 2 [Homo sapiens]              183   5e-46
gi|29171714 melanoma antigen family B, 3 [Homo sapiens]               180   4e-45
gi|153791873 melanoma antigen family B, 16 [Homo sapiens]             179   7e-45
gi|27734781 melanoma antigen family B, 18 [Homo sapiens]              176   4e-44
gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   176   6e-44
gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   176   6e-44
gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo sapi...   176   6e-44
gi|58530863 melanoma antigen family A, 10 [Homo sapiens]              176   6e-44
gi|10567820 melanoma antigen family A, 10 [Homo sapiens]              176   6e-44
gi|29171711 melanoma antigen family B, 1 [Homo sapiens]               175   9e-44

>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 1172 bits (3031), Expect = 0.0
 Identities = 606/606 (100%), Positives = 606/606 (100%)

Query: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60
           MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60

Query: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120
           SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA
Sbjct: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120

Query: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180
           TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
Sbjct: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180

Query: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240
           KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR
Sbjct: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240

Query: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300
           ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI
Sbjct: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300

Query: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360
           KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
Sbjct: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360

Query: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420
           GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF
Sbjct: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420

Query: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480
           VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME
Sbjct: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480

Query: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540
           ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK
Sbjct: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540

Query: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600
           AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA
Sbjct: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600

Query: 601 CGFSYK 606
           CGFSYK
Sbjct: 601 CGFSYK 606


>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 1172 bits (3031), Expect = 0.0
 Identities = 606/606 (100%), Positives = 606/606 (100%)

Query: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60
           MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60

Query: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120
           SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA
Sbjct: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120

Query: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180
           TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
Sbjct: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180

Query: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240
           KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR
Sbjct: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240

Query: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300
           ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI
Sbjct: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300

Query: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360
           KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
Sbjct: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360

Query: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420
           GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF
Sbjct: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420

Query: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480
           VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME
Sbjct: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480

Query: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540
           ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK
Sbjct: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540

Query: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600
           AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA
Sbjct: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600

Query: 601 CGFSYK 606
           CGFSYK
Sbjct: 601 CGFSYK 606


>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
          Length = 606

 Score = 1172 bits (3031), Expect = 0.0
 Identities = 606/606 (100%), Positives = 606/606 (100%)

Query: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60
           MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA
Sbjct: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKA 60

Query: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120
           SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA
Sbjct: 61  SGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPA 120

Query: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180
           TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV
Sbjct: 121 TETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKV 180

Query: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240
           KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR
Sbjct: 181 KHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARR 240

Query: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300
           ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI
Sbjct: 241 ALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPI 300

Query: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360
           KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL
Sbjct: 301 KRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGIL 360

Query: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420
           GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF
Sbjct: 361 GTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEF 420

Query: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480
           VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME
Sbjct: 421 VKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAME 480

Query: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540
           ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK
Sbjct: 481 ADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAK 540

Query: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600
           AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA
Sbjct: 541 AQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600

Query: 601 CGFSYK 606
           CGFSYK
Sbjct: 601 CGFSYK 606


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  446 bits (1146), Expect = e-125
 Identities = 279/616 (45%), Positives = 364/616 (59%), Gaps = 71/616 (11%)

Query: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234

Query: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294

Query: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346

Query: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402

Query: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462

Query: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521

Query: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581

Query: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641

Query: 478 AMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADI--------GPWAKA 529
           A+E +++AAA A AEA+ARAE RA+MGIG   E  AGP NWD+ DI        G  A+A
Sbjct: 642 AVEMEVQAAAVAVAEAEARAEARAQMGIG--EEAVAGPWNWDDMDIDCLTREELGDDAQA 699

Query: 530 RIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGG 589
             +   E +A+AQE+      A  STN + S  AST  GFS GAS++            G
Sbjct: 700 WSRFSFEIEARAQEN------ADASTNVNFSRGASTRAGFSDGASIS----------FNG 743

Query: 590 AGASTSGSSGACGFSY 605
           A +S+ G SG  G ++
Sbjct: 744 APSSSGGFSGGPGITF 759



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 53/238 (22%), Positives = 90/238 (37%), Gaps = 28/238 (11%)

Query: 15  QAEASEKDSSSMMQTLLTVTQN--------VEVPETPKASKALEVSEDVKVSKASGVSKA 66
           Q E +E+DS  +M TLL  T++        V  P+  K  KA   +       A  V  A
Sbjct: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAA 92

Query: 67  TEVSK-----TPEAREAPA----TQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVT 117
            E++      T +A   P     +QA  TT++T+TQ       S+ A  KK N   +   
Sbjct: 93  NEIATNKPKITWQALNLPVITQISQALPTTEVTNTQA-----SSVTAQPKKANKMKRVTA 147

Query: 118 MPATETKK-VSHVADT-KVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAK 175
             A  ++    H   T ++ +  Q  +          P     A +S  +Q     +K K
Sbjct: 148 KAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAP----IANESASSQALITSIKPK 203

Query: 176 KARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233
           KA K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 204 KASKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 27/68 (39%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 544  SGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSG------S 597
            SG  STG    +  S S     SGG S GA        G  AG GG  ++++G      S
Sbjct: 1368 SGGPSTGVGFCSGPSTSGF---SGGPSTGAGFGGGPNTG--AGFGGGPSTSAGFGSGAAS 1422

Query: 598  SGACGFSY 605
             GACGFSY
Sbjct: 1423 LGACGFSY 1430



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 544  SGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGL--FAGLGGAGASTSGSSGAC 601
            S S   G STST  S     ST+ GF  G + +A    GL   AG  G  +++SG  G  
Sbjct: 1184 SPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGL 1243

Query: 602  GFS 604
            G S
Sbjct: 1244 GTS 1246



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)

Query: 544  SGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFA--GLGGAGASTSGSSGA 600
            S SA  G + +TN S   + STS  FS   S +A  +       G GGA ++++G  GA
Sbjct: 1054 STSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGA 1112



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 550  GASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLG-GAGASTSGSSG 599
            G+ ++T+   +   STS GFS+G S     + G   G+G  +G STSG SG
Sbjct: 1338 GSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSG 1388



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 8/59 (13%)

Query: 546  SASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFS 604
            SA  G    T+   S   STS GF  G         G  AG GG   +++G  G  G S
Sbjct: 1216 SAGFGGGLGTSAGFSGGLSTSSGFDGG--------LGTSAGFGGGPGTSTGFGGGLGTS 1266



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 6/66 (9%)

Query: 545  GSASTGA--STSTNNSASASASTSGGFSAGASLTATLTFG----LFAGLGGAGASTSGSS 598
            G  ST A  S +T+ S     STS GFS G  L+    FG      AG GG   +++G S
Sbjct: 1171 GPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFS 1230

Query: 599  GACGFS 604
            G    S
Sbjct: 1231 GGLSTS 1236



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 5/57 (8%)

Query: 544 SGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGA 600
           S S S G S+S +   S SA+ SGG S+G   T + T G F+G+     STS S G+
Sbjct: 820 SASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAG-FSGV----LSTSTSFGS 871


>gi|29540551 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  395 bits (1014), Expect = e-110
 Identities = 236/502 (47%), Positives = 307/502 (61%), Gaps = 45/502 (8%)

Query: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234

Query: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294

Query: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346

Query: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402

Query: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462

Query: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521

Query: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581

Query: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641

Query: 478 AMEADLKAAAEAAAEAKARAEI 499
           A+E +++AAA A AEA+ARAEI
Sbjct: 642 AVEMEVQAAAVAVAEAEARAEI 663



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 53/238 (22%), Positives = 90/238 (37%), Gaps = 28/238 (11%)

Query: 15  QAEASEKDSSSMMQTLLTVTQN--------VEVPETPKASKALEVSEDVKVSKASGVSKA 66
           Q E +E+DS  +M TLL  T++        V  P+  K  KA   +       A  V  A
Sbjct: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAA 92

Query: 67  TEVSK-----TPEAREAPA----TQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVT 117
            E++      T +A   P     +QA  TT++T+TQ       S+ A  KK N   +   
Sbjct: 93  NEIATNKPKITWQALNLPVITQISQALPTTEVTNTQA-----SSVTAQPKKANKMKRVTA 147

Query: 118 MPATETKK-VSHVADT-KVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAK 175
             A  ++    H   T ++ +  Q  +          P     A +S  +Q     +K K
Sbjct: 148 KAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAP----IANESASSQALITSIKPK 203

Query: 176 KARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233
           KA K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 204 KASKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261


>gi|29540541 trophinin isoform 2 [Homo sapiens]
          Length = 706

 Score =  395 bits (1014), Expect = e-110
 Identities = 236/502 (47%), Positives = 307/502 (61%), Gaps = 45/502 (8%)

Query: 30  LLTVTQNVEVPETPKASKALEVSEDVKVSKAS--------GVSKATEVSKTPEAREAPAT 81
           L  ++QN+  P   +++ +  +   +K  KAS         ++ ATEVS    A     T
Sbjct: 175 LPVISQNIHAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATT 234

Query: 82  QASSTTQLTDTQVLAAENKSLAA-----------DTKKQNADPQAVTMPATETKKVSHVA 130
           Q   T +       AA  ++  A           +T  ++ +   VT  AT   + S VA
Sbjct: 235 QGQITNETASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVA 294

Query: 131 DTKVNTKAQETEAAPSQAPADEPEPESA--AAQSQENQDTRPKVKAKKARKVKHLDGEED 188
              +  K  + + A S+ P    E   A  A Q   NQ     ++ K+  + +     + 
Sbjct: 295 ---IRPKKSKGKKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRAR-----KA 346

Query: 189 GSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSP 248
            +  ++  S T    + ++A +AS     S    A   + A+  +  A    A LSL   
Sbjct: 347 ATKARATESQTPNADQGAQAKIASAQTNVS----ALETQVAAAVQALADDYLAQLSLEPT 402

Query: 249 KARRGKARRRAAKLQSSQEPEA-----------PPPRDVALLQGRANDLVKYLLAKDQTK 297
              RGK  R++  L   +   +            PPRDVA+LQ RAN LVKYLL KDQTK
Sbjct: 403 TRTRGKRNRKSKHLNGDERSGSNYRRIPWGRRPAPPRDVAILQERANKLVKYLLVKDQTK 462

Query: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357
           IPIKRSDML+D+I+EY + +PEIIERA Y+LEK+F + LKEIDK   LYIL+ST E + A
Sbjct: 463 IPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKEIDKQSSLYILISTQE-SSA 521

Query: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417
           GILGTTKD+PKLGLLMV+LS+IFMNGN++SEAVIWEVLRKLGLRPG+ HSLFG+V+KLIT
Sbjct: 522 GILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLRPGVRHSLFGEVRKLIT 581

Query: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477
           DEFVKQKYL+Y RVPNS PPEYEFFWGLRSY+ETSKMKVLKFAC+VQKKDPK+WA QYRE
Sbjct: 582 DEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACRVQKKDPKDWAVQYRE 641

Query: 478 AMEADLKAAAEAAAEAKARAEI 499
           A+E +++AAA A AEA+ARAEI
Sbjct: 642 AVEMEVQAAAVAVAEAEARAEI 663



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 53/238 (22%), Positives = 90/238 (37%), Gaps = 28/238 (11%)

Query: 15  QAEASEKDSSSMMQTLLTVTQN--------VEVPETPKASKALEVSEDVKVSKASGVSKA 66
           Q E +E+DS  +M TLL  T++        V  P+  K  KA   +       A  V  A
Sbjct: 33  QTETTEEDSVLLMHTLLAATKDSLAMDPPVVNRPKKSKTKKAPIKTITKAAPAAPPVPAA 92

Query: 67  TEVSK-----TPEAREAPA----TQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVT 117
            E++      T +A   P     +QA  TT++T+TQ       S+ A  KK N   +   
Sbjct: 93  NEIATNKPKITWQALNLPVITQISQALPTTEVTNTQA-----SSVTAQPKKANKMKRVTA 147

Query: 118 MPATETKK-VSHVADT-KVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAK 175
             A  ++    H   T ++ +  Q  +          P     A +S  +Q     +K K
Sbjct: 148 KAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNIHAP----IANESASSQALITSIKPK 203

Query: 176 KARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTR 233
           KA K K    +   S+ +   + T      ++  + +          +   ++AS+ R
Sbjct: 204 KASKAKKAANKAIASATEVSLAATATHTATTQGQITNETASIHTTAASIRTKKASKAR 261


>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
          Length = 834

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 505 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 564

Query: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 565 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 623

Query: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 624 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 683

Query: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 684 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 743

Query: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 744 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 800

Query: 545 GSASTGASTSTNNSASASASTSGGFSA 571
               T A        +ASA+ +  F A
Sbjct: 801 RFPQTFAGPIIGPGGTASANFAANFGA 827



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 78/319 (24%), Positives = 122/319 (38%), Gaps = 77/319 (24%)

Query: 10  GLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE----------DVKVSK 59
           G +   AEAS +DS+ +MQTL+   Q  E P T +A+ A               D++VS 
Sbjct: 66  GASPAPAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTANEMADIQVSA 125

Query: 60  ASGVSKAT---------------EVSKTPEAREAPATQASST-----------------T 87
           A+   K+                + S+   A++ P TQ  +                  +
Sbjct: 126 AAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPKGPNAAYDFS 185

Query: 88  QLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATETKKVSHV-- 129
           Q   T  LAA    +A     A TK             NA+  A + P T  K  +    
Sbjct: 186 QAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTPFKAWNDTTK 245

Query: 130 ---ADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDTRPKVKAKKA 177
              ADT+   VN     T  A  +      EP+ A AQ+       +N ++R  ++ K+ 
Sbjct: 246 APTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLESRTIIRGKRT 305

Query: 178 RKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAW 237
           RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W    +    + W
Sbjct: 306 RKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTPLAWQNPSGW 364

Query: 238 ----ARRALLSLRSPKARR 252
               AR+   + +SP AR+
Sbjct: 365 QNQTARQTPPARQSPPARQ 383


>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 449 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508

Query: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 567

Query: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 568 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 627

Query: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 628 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 687

Query: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 688 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 744

Query: 545 GSASTGASTSTNNSASASASTSGGFSA 571
               T A        +ASA+ +  F A
Sbjct: 745 RFPQTFAGPIIGPGGTASANFAANFGA 771



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 85/328 (25%), Positives = 129/328 (39%), Gaps = 77/328 (23%)

Query: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE------- 53
           M+   + GAGL  FQAEAS +DS+ +MQTL+   Q  E P T +A+ A            
Sbjct: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60

Query: 54  ---DVKVSKASGVSKAT---------------EVSKTPEAREAPATQ------------- 82
              D++VS A+   K+                + S+   A++ P TQ             
Sbjct: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120

Query: 83  ----ASSTTQLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATE 122
               A   +Q   T  LAA    +A     A TK             NA+  A + P T 
Sbjct: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180

Query: 123 TK-----KVSHVADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDT 168
            K       +  ADT+   VN     T  A  +      EP+ A AQ+       +N ++
Sbjct: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240

Query: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARR 228
           R  ++ K+ RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W   
Sbjct: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTP 299

Query: 229 ASRTRLAAW----ARRALLSLRSPKARR 252
            +    + W    AR+   + +SP AR+
Sbjct: 300 LAWQNPSGWQNQTARQTPPARQSPPARQ 327


>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
          Length = 778

 Score =  370 bits (951), Expect = e-102
 Identities = 198/327 (60%), Positives = 237/327 (72%), Gaps = 16/327 (4%)

Query: 257 RRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDV 316
           R +   ++SQ P A  PRDVALLQ RAN LVKYL+ KD TK+PIKRS+ML+DII+EYTDV
Sbjct: 449 RPSPNSRASQNPGAAQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDV 508

Query: 317 YPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLL 376
           YPEIIERA + LEK FGIQLKEIDK +HLYIL+ST E   AGILGTTKD+PKLGLL+V+L
Sbjct: 509 YPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESL-AGILGTTKDTPKLGLLLVIL 567

Query: 377 SIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNP 436
            +IFMNGNR+SEAV+WE LRK+GLRPG+ H L GD++KL+T EFVKQKYLDY RVPNSNP
Sbjct: 568 GVIFMNGNRASEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP 627

Query: 437 PEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKAR 496
           PEYEF WGLRSY+ETSKMKVL+F  +VQK+DP++W AQ+ EA +  L A   AAAEA+AR
Sbjct: 628 PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEAR 687

Query: 497 AEIRARMGIGLGSENAAGPCNWD-----------EADIG-PWAKARIQAGAEAKAKAQES 544
           AE R RMGI  G E  +GP +WD           E D G PW++      A     A+ S
Sbjct: 688 AEARTRMGI--GDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR-S 744

Query: 545 GSASTGASTSTNNSASASASTSGGFSA 571
               T A        +ASA+ +  F A
Sbjct: 745 RFPQTFAGPIIGPGGTASANFAANFGA 771



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 85/328 (25%), Positives = 129/328 (39%), Gaps = 77/328 (23%)

Query: 1   MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSE------- 53
           M+   + GAGL  FQAEAS +DS+ +MQTL+   Q  E P T +A+ A            
Sbjct: 1   MAQKMDCGAGLLGFQAEASVEDSALLMQTLMEAIQISEAPPTNQATAAASPQSSQPPTAN 60

Query: 54  ---DVKVSKASGVSKAT---------------EVSKTPEAREAPATQ------------- 82
              D++VS A+   K+                + S+   A++ P TQ             
Sbjct: 61  EMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQPKAAFKSQNATPK 120

Query: 83  ----ASSTTQLTDTQVLAAENKSLA-----ADTK-----------KQNADPQAVTMPATE 122
               A   +Q   T  LAA    +A     A TK             NA+  A + P T 
Sbjct: 121 GPNAAYDFSQAATTGELAANKSEMAFKAQNATTKVGPNATYNFSQSLNANDLANSRPKTP 180

Query: 123 TK-----KVSHVADTK---VNTKAQETEAAPSQAPADEPEPESAAAQSQ------ENQDT 168
            K       +  ADT+   VN     T  A  +      EP+ A AQ+       +N ++
Sbjct: 181 FKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGISEPDGATAQTSADGSQAQNLES 240

Query: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARR 228
           R  ++ K+ RK+ +L+ EE+ S DQ +A    G  R S  +  +        P   W   
Sbjct: 241 RTIIRGKRTRKINNLNVEENSSGDQRRAPLAAGTWR-SAPVPVTTQNPPGAPPNVLWQTP 299

Query: 229 ASRTRLAAW----ARRALLSLRSPKARR 252
            +    + W    AR+   + +SP AR+
Sbjct: 300 LAWQNPSGWQNQTARQTPPARQSPPARQ 327


>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
          Length = 739

 Score =  350 bits (897), Expect = 3e-96
 Identities = 233/623 (37%), Positives = 321/623 (51%), Gaps = 99/623 (15%)

Query: 12  TRFQAEAS----EKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKAT 67
           T + AEA     E   +S   + + VT  +  PE P  S   +     + +   G S A 
Sbjct: 150 TTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSAC 209

Query: 68  EVSKTPEAREAPATQASST------------------------TQLTDTQVLAAENKSLA 103
             S+ P ARE  A + S+                          +    Q  A E  S A
Sbjct: 210 AFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSAA 269

Query: 104 ADTKKQNADPQ-AVTMPATETKKVSHVADTKVNTKAQETEAAPSQAP--ADEPEPE-SAA 159
           +   +     + A T P T TK    +A T+         AA ++A      PEPE +AA
Sbjct: 270 SGVPQTGPGREVAATRPKT-TKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAA 328

Query: 160 AQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASR 219
           A +Q + +   ++  K+ +K KHLD E + S ++ +        R S+  +   A+ A R
Sbjct: 329 ATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPR 388

Query: 220 GPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALL 279
            P+A  ++  SR  L                                     PPR+V LL
Sbjct: 389 PPMAPRSQIPSRHVLCL-----------------------------------PPRNVTLL 413

Query: 280 QGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEI 339
           Q RAN LVKYL+ KD  KIPIKR+DMLKD+I+EY + +PEIIERA Y+LEK FGI LKEI
Sbjct: 414 QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEI 473

Query: 340 DKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLG 399
           DK +HLYIL+ T + + A +LG TKD+P+L LL+V+L +IFMNGNR+SEAV+WE LRK+G
Sbjct: 474 DKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMG 532

Query: 400 LRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKF 459
           LRPG+ H   GD++KLITD+FVKQKYL+Y ++PNSNPPEYEF WGLR+ +ETSKM+VL+F
Sbjct: 533 LRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRF 592

Query: 460 ACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWD 519
             + Q +DP+EW A + EA++   K      AE  ARA++RA+M I  G E   G  +WD
Sbjct: 593 IAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQMRAQMNI--GDEALIGRWSWD 650

Query: 520 EADI------------GPWAKARI--------------QAGAEAKAKAQESGSASTGAST 553
           +  +              WA+                 +A   A  +A  S   + GAST
Sbjct: 651 DIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGAST 710

Query: 554 STNNSASASAS--TSGGFSAGAS 574
           S  +  S S++  T     AGAS
Sbjct: 711 SVLDGPSTSSTIRTRNAARAGAS 733


>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  350 bits (897), Expect = 3e-96
 Identities = 233/623 (37%), Positives = 321/623 (51%), Gaps = 99/623 (15%)

Query: 12  TRFQAEAS----EKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKAT 67
           T + AEA     E   +S   + + VT  +  PE P  S   +     + +   G S A 
Sbjct: 150 TTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSAC 209

Query: 68  EVSKTPEAREAPATQASST------------------------TQLTDTQVLAAENKSLA 103
             S+ P ARE  A + S+                          +    Q  A E  S A
Sbjct: 210 AFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSAA 269

Query: 104 ADTKKQNADPQ-AVTMPATETKKVSHVADTKVNTKAQETEAAPSQAP--ADEPEPE-SAA 159
           +   +     + A T P T TK    +A T+         AA ++A      PEPE +AA
Sbjct: 270 SGVPQTGPGREVAATRPKT-TKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAA 328

Query: 160 AQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASR 219
           A +Q + +   ++  K+ +K KHLD E + S ++ +        R S+  +   A+ A R
Sbjct: 329 ATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPR 388

Query: 220 GPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALL 279
            P+A  ++  SR  L                                     PPR+V LL
Sbjct: 389 PPMAPRSQIPSRHVLCL-----------------------------------PPRNVTLL 413

Query: 280 QGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEI 339
           Q RAN LVKYL+ KD  KIPIKR+DMLKD+I+EY + +PEIIERA Y+LEK FGI LKEI
Sbjct: 414 QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEI 473

Query: 340 DKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLG 399
           DK +HLYIL+ T + + A +LG TKD+P+L LL+V+L +IFMNGNR+SEAV+WE LRK+G
Sbjct: 474 DKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMG 532

Query: 400 LRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKF 459
           LRPG+ H   GD++KLITD+FVKQKYL+Y ++PNSNPPEYEF WGLR+ +ETSKM+VL+F
Sbjct: 533 LRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRF 592

Query: 460 ACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWD 519
             + Q +DP+EW A + EA++   K      AE  ARA++RA+M I  G E   G  +WD
Sbjct: 593 IAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQMRAQMNI--GDEALIGRWSWD 650

Query: 520 EADI------------GPWAKARI--------------QAGAEAKAKAQESGSASTGAST 553
           +  +              WA+                 +A   A  +A  S   + GAST
Sbjct: 651 DIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGAST 710

Query: 554 STNNSASASAS--TSGGFSAGAS 574
           S  +  S S++  T     AGAS
Sbjct: 711 SVLDGPSTSSTIRTRNAARAGAS 733


>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
          Length = 741

 Score =  350 bits (897), Expect = 3e-96
 Identities = 233/623 (37%), Positives = 321/623 (51%), Gaps = 99/623 (15%)

Query: 12  TRFQAEAS----EKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKAT 67
           T + AEA     E   +S   + + VT  +  PE P  S   +     + +   G S A 
Sbjct: 150 TTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSAC 209

Query: 68  EVSKTPEAREAPATQASST------------------------TQLTDTQVLAAENKSLA 103
             S+ P ARE  A + S+                          +    Q  A E  S A
Sbjct: 210 AFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSAA 269

Query: 104 ADTKKQNADPQ-AVTMPATETKKVSHVADTKVNTKAQETEAAPSQAP--ADEPEPE-SAA 159
           +   +     + A T P T TK    +A T+         AA ++A      PEPE +AA
Sbjct: 270 SGVPQTGPGREVAATRPKT-TKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAA 328

Query: 160 AQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASR 219
           A +Q + +   ++  K+ +K KHLD E + S ++ +        R S+  +   A+ A R
Sbjct: 329 ATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPR 388

Query: 220 GPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALL 279
            P+A  ++  SR  L                                     PPR+V LL
Sbjct: 389 PPMAPRSQIPSRHVLCL-----------------------------------PPRNVTLL 413

Query: 280 QGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEI 339
           Q RAN LVKYL+ KD  KIPIKR+DMLKD+I+EY + +PEIIERA Y+LEK FGI LKEI
Sbjct: 414 QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEI 473

Query: 340 DKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLG 399
           DK +HLYIL+ T + + A +LG TKD+P+L LL+V+L +IFMNGNR+SEAV+WE LRK+G
Sbjct: 474 DKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMG 532

Query: 400 LRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKF 459
           LRPG+ H   GD++KLITD+FVKQKYL+Y ++PNSNPPEYEF WGLR+ +ETSKM+VL+F
Sbjct: 533 LRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRF 592

Query: 460 ACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWD 519
             + Q +DP+EW A + EA++   K      AE  ARA++RA+M I  G E   G  +WD
Sbjct: 593 IAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQMRAQMNI--GDEALIGRWSWD 650

Query: 520 EADI------------GPWAKARI--------------QAGAEAKAKAQESGSASTGAST 553
           +  +              WA+                 +A   A  +A  S   + GAST
Sbjct: 651 DIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGAST 710

Query: 554 STNNSASASAS--TSGGFSAGAS 574
           S  +  S S++  T     AGAS
Sbjct: 711 SVLDGPSTSSTIRTRNAARAGAS 733


>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
          Length = 739

 Score =  350 bits (897), Expect = 3e-96
 Identities = 233/623 (37%), Positives = 321/623 (51%), Gaps = 99/623 (15%)

Query: 12  TRFQAEAS----EKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKAT 67
           T + AEA     E   +S   + + VT  +  PE P  S   +     + +   G S A 
Sbjct: 150 TTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSAC 209

Query: 68  EVSKTPEAREAPATQASST------------------------TQLTDTQVLAAENKSLA 103
             S+ P ARE  A + S+                          +    Q  A E  S A
Sbjct: 210 AFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSAA 269

Query: 104 ADTKKQNADPQ-AVTMPATETKKVSHVADTKVNTKAQETEAAPSQAP--ADEPEPE-SAA 159
           +   +     + A T P T TK    +A T+         AA ++A      PEPE +AA
Sbjct: 270 SGVPQTGPGREVAATRPKT-TKSGKALAKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAA 328

Query: 160 AQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASR 219
           A +Q + +   ++  K+ +K KHLD E + S ++ +        R S+  +   A+ A R
Sbjct: 329 ATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEERETPAVPPTWRASQPSLTVRAQLAPR 388

Query: 220 GPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALL 279
            P+A  ++  SR  L                                     PPR+V LL
Sbjct: 389 PPMAPRSQIPSRHVLCL-----------------------------------PPRNVTLL 413

Query: 280 QGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEI 339
           Q RAN LVKYL+ KD  KIPIKR+DMLKD+I+EY + +PEIIERA Y+LEK FGI LKEI
Sbjct: 414 QERANKLVKYLMIKDYKKIPIKRADMLKDVIREYDEHFPEIIERATYTLEKKFGIHLKEI 473

Query: 340 DKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLG 399
           DK +HLYIL+ T + + A +LG TKD+P+L LL+V+L +IFMNGNR+SEAV+WE LRK+G
Sbjct: 474 DKEEHLYILVCTRD-SSARLLGKTKDTPRLSLLLVILGVIFMNGNRASEAVLWEALRKMG 532

Query: 400 LRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKF 459
           LRPG+ H   GD++KLITD+FVKQKYL+Y ++PNSNPPEYEF WGLR+ +ETSKM+VL+F
Sbjct: 533 LRPGVRHPFLGDLRKLITDDFVKQKYLEYKKIPNSNPPEYEFLWGLRARHETSKMRVLRF 592

Query: 460 ACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWD 519
             + Q +DP+EW A + EA++   K      AE  ARA++RA+M I  G E   G  +WD
Sbjct: 593 IAQNQNRDPREWKAHFLEAVDDAFKTMDVDMAEEHARAQMRAQMNI--GDEALIGRWSWD 650

Query: 520 EADI------------GPWAKARI--------------QAGAEAKAKAQESGSASTGAST 553
           +  +              WA+                 +A   A  +A  S   + GAST
Sbjct: 651 DIQVELLTWDEDGDFGDAWARIPFAFWARYHQYILNSNRANRRATWRAGVSSGTNGGAST 710

Query: 554 STNNSASASAS--TSGGFSAGAS 574
           S  +  S S++  T     AGAS
Sbjct: 711 SVLDGPSTSSTIRTRNAARAGAS 733


>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
          Length = 307

 Score =  221 bits (564), Expect = 1e-57
 Identities = 140/333 (42%), Positives = 195/333 (58%), Gaps = 43/333 (12%)

Query: 180 VKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWAR 239
           V   +GE+DG  D    + T    R  + L A     A+   +    R+ +R    A A 
Sbjct: 12  VPQAEGEKDGGHDGETRAPTASQERPKEELGAGREEGAAEPALT---RKGAR----ALAA 64

Query: 240 RALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIP 299
           +AL            ARRRA +  +         R VA       +LV++LL KD+ K P
Sbjct: 65  KAL------------ARRRAYRRLN---------RTVA-------ELVQFLLVKDKKKSP 96

Query: 300 IKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGI 359
           I RS+M+K +I +   ++P+II RA   L  VFG +LK+ D+  H YIL++ L+P +   
Sbjct: 97  ITRSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEE 156

Query: 360 ---LGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLI 416
              LG   D P+LGLLM++L +I+M GN + EA +WE+LR+LG++P  +H LFG  K+LI
Sbjct: 157 EEDLGG--DGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLI 214

Query: 417 TDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYR 476
            ++FV+Q+YL Y RVP++NPPEYEF WG RS  E SKM+VL F  K+ KK+P+ W  QYR
Sbjct: 215 MEDFVQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYR 274

Query: 477 EAM--EADLKAAAEAAAEAKARAEIRARMGIGL 507
           EA+  EAD +A A+A AEA  RA   AR GI L
Sbjct: 275 EALADEAD-RARAKARAEASMRARASARAGIHL 306


>gi|20162572 necdin-like 2 [Homo sapiens]
          Length = 304

 Score =  220 bits (560), Expect = 3e-57
 Identities = 116/264 (43%), Positives = 168/264 (63%), Gaps = 3/264 (1%)

Query: 218 SRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVA 277
           S  P A  A   +R     +A  A  + R P   +G         + +Q   A  PR   
Sbjct: 24  SGNPGASRAGEDARVLRDGFAEEAPSTSRGPGGSQGSQGPSPQGARRAQAAPAVGPRSQK 83

Query: 278 LLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLK 337
            L+ + ++LV++LL KDQ KIPIKR+D+LK +I +Y D++P++ +RA   L+ VFG +L 
Sbjct: 84  QLELKVSELVQFLLIKDQKKIPIKRADILKHVIGDYKDIFPDLFKRAAERLQYVFGYKLV 143

Query: 338 EIDKNDHLYILLSTLEPT--DAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVL 395
           E++   + YIL++TLEP   DA + G  + +P  GLLM++L +IFM GN   E   W+ L
Sbjct: 144 ELEPKSNTYILINTLEPVEEDAEMRGD-QGTPTTGLLMIVLGLIFMKGNTIKETEAWDFL 202

Query: 396 RKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMK 455
           R+LG+ P   H +FGD KKLIT++FV+Q+YL+Y R+P+++P +YEF WG R+  ETSKMK
Sbjct: 203 RRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYEFQWGPRTNLETSKMK 262

Query: 456 VLKFACKVQKKDPKEWAAQYREAM 479
           VLKF  KV  +DPK+W AQY EA+
Sbjct: 263 VLKFVAKVHNQDPKDWPAQYCEAL 286


>gi|148746206 MAGE-like protein 2 [Homo sapiens]
          Length = 646

 Score =  218 bits (555), Expect = 1e-56
 Identities = 159/449 (35%), Positives = 223/449 (49%), Gaps = 48/449 (10%)

Query: 72  TPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMP---ATETKKVSH 128
           TPE     ++   +T+Q     + A +  S A++T K    P A+  P         V  
Sbjct: 176 TPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSL--PYALQDPFACVEALPAVPW 233

Query: 129 VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTR---PKVKAKKARKVKHLDG 185
           V    +N  ++ ++A P+   A    P+ A A +QE   T    P+   K  RK KHL+ 
Sbjct: 234 VPQPNMNA-SKASQAVPTFLMATAAAPQ-ATATTQEASKTSVEPPRRSGKATRKKKHLEA 291

Query: 186 EEDGSSD-----------------------QS--QASGTTGGRRVSKALMASMARRASR- 219
           +ED                           QS  Q SG        + L        SR 
Sbjct: 292 QEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRI 351

Query: 220 -----GPIAFWARRA----SRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA 270
                GP A WA  A    S +R    +     SL    +        ++  Q + + EA
Sbjct: 352 LSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEA 411

Query: 271 PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEK 330
            P   ++ L  RAN LV++LL KDQ K+P++RS+M+K I++EY D   +II RA   LE 
Sbjct: 412 QP---LSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLEC 468

Query: 331 VFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAV 390
            FG QLKEID  +H YI+++ L      ++ +  D PK GLLMV+LS+IFM GN   E +
Sbjct: 469 AFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDL 528

Query: 391 IWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYE 450
           I+  L KLGL     + LFG+ KKLIT+ FV+QKYL+Y R+P + P EYEF WG R++ E
Sbjct: 529 IFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLE 588

Query: 451 TSKMKVLKFACKVQKKDPKEWAAQYREAM 479
           TSKM VL+F  K+ KKDP+ W   Y EA+
Sbjct: 589 TSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score =  203 bits (517), Expect = 3e-52
 Identities = 145/452 (32%), Positives = 229/452 (50%), Gaps = 50/452 (11%)

Query: 43  PKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSL 102
           P A++ L  S    V   +G   +T V  TP    + +   ++T +L+ T V     +  
Sbjct: 298 PTATEGLSTS----VQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELS-TSVPPTPGEGP 352

Query: 103 AADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQS 162
           +        +  + ++P T     S  +DT V     E  +   Q  A +    S     
Sbjct: 353 STSVLPIPGEGLSTSVPPT----ASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPNP 408

Query: 163 QENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMAR--RASRG 220
            E   T     A   R             + S+ S      RV+KA + S +   + + G
Sbjct: 409 GEGPSTLFSSSASVDR-------------NPSKCSLVLPSPRVTKASVDSDSEGPKGAEG 455

Query: 221 PIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQ 280
           PI F   R   +  +     +++ L +            +++  + +P+ P  ++VA   
Sbjct: 456 PIEFEVLRDCESPNSI----SIMGLNT------------SRVAITLKPQDPMEQNVA--- 496

Query: 281 GRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEID 340
               +L+++LL KDQ+K PI+ S+M + I+KEY + +PEI+ RA   LE +F  +L+E+D
Sbjct: 497 ----ELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLECIFRFELRELD 552

Query: 341 KNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGL 400
              H YILL+ L P     L  + + PK+GLLM++L  IF+NGN++ EA IWE+L ++G+
Sbjct: 553 PEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEAEIWEMLWRMGV 612

Query: 401 RPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFA 460
           +     S+FG+ K+L++ EFV Q+YLDY  V +  P EYEFFWG RS+ ET+KMK+LKF 
Sbjct: 613 QRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHLETTKMKILKFM 672

Query: 461 CKVQKKDPKEWAAQYREAMEADLKAAAEAAAE 492
            K+  KDP +W  +Y EA+E D   AA A AE
Sbjct: 673 AKIYNKDPMDWPEKYNEALEED---AARAFAE 701



 Score =  154 bits (389), Expect = 2e-37
 Identities = 80/227 (35%), Positives = 131/227 (57%), Gaps = 8/227 (3%)

Query: 260 AKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPE 319
           +++ S     AP     + L+ +A  LV+  L  D TK+PI +  +L  I +E + V+P+
Sbjct: 726 SEVSSYSSKYAPHSWPESRLESKARKLVQLFLLMDSTKLPIPKKGILYYIGRECSKVFPD 785

Query: 320 IIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSII 379
           ++ RA  +L  V+G +L  +D  +H Y L +  E  +   +  + + P    LM +LS I
Sbjct: 786 LLNRAARTLNHVYGTELVVLDPRNHSYTLYNRREMEETEEIVDSPNRPGNNFLMQVLSFI 845

Query: 380 FMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEY 439
           F+ GN + E+ +W  LR LG++ G  H        +IT  ++ Q+Y+D  RVP+S+P +Y
Sbjct: 846 FIMGNHARESAVWAFLRGLGVQAGRKH--------VITCRYLSQRYIDSLRVPDSDPVQY 897

Query: 440 EFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAA 486
           EF WG R+  ETSKMK L++  ++ +K+P++W  QYREAME +   A
Sbjct: 898 EFVWGPRARLETSKMKALRYVARIHRKEPQDWPQQYREAMEDEANRA 944



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 35/145 (24%), Positives = 54/145 (37%), Gaps = 14/145 (9%)

Query: 41  ETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPAT-------QASSTTQL---- 89
           E P  S     SE    S      + T  S  P A E P+T       +  ST+ L    
Sbjct: 146 EEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPG 205

Query: 90  --TDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVS-HVADTKVNTKAQETEAAPS 146
               T V  A  + L+   +    +  + ++P T T+ +S  V  T+    +    A P 
Sbjct: 206 EGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPG 265

Query: 147 QAPADEPEPESAAAQSQENQDTRPK 171
           + P+    P ++  QS     TR K
Sbjct: 266 EGPSTSVLPAASDGQSISLVPTRGK 290


>gi|4505349 necdin [Homo sapiens]
          Length = 321

 Score =  191 bits (485), Expect = 2e-48
 Identities = 103/243 (42%), Positives = 151/243 (62%), Gaps = 3/243 (1%)

Query: 248 PKARRGKARR-RAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDML 306
           PKA +  A   RA +  S+ +P   PP    L+Q +A++L+ Y+L KDQ K+ I   DM+
Sbjct: 67  PKALQQAAEEGRAHQAPSAAQPGPAPPAPAQLVQ-KAHELMWYVLVKDQKKMIIWFPDMV 125

Query: 307 KDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDS 366
           KD+I  Y      I+ R    L +VFG+ L+    +   + L+  LEP +   +  +   
Sbjct: 126 KDVIGSYKKWCRSILRRTSLILARVFGLHLRLTSLHTMEFALVKALEPEELDRVALSNRM 185

Query: 367 PKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYL 426
           P  GLL+++LS+I++ G  + E+ +W VLR LGLRP   HS FGDV+KLIT+EFV+  YL
Sbjct: 186 PMTGLLLMILSLIYVKGRGARESAVWNVLRILGLRPWKKHSTFGDVRKLITEEFVQMNYL 245

Query: 427 DYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAA 486
            Y RVP   PPEYEFFWG R+  E +KM++++F  +V KKDP+ W ++YREA+E + +A 
Sbjct: 246 KYQRVPYVEPPEYEFFWGSRASREITKMQIMEFLARVFKKDPQAWPSRYREALE-EARAL 304

Query: 487 AEA 489
            EA
Sbjct: 305 REA 307


>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
          Length = 347

 Score =  187 bits (475), Expect = 2e-47
 Identities = 96/218 (44%), Positives = 139/218 (63%), Gaps = 1/218 (0%)

Query: 286 LVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHL 345
           LV YLL K Q K PI ++DML+++ +     +P I+ RA   LE +FG+ LKE++ N H+
Sbjct: 118 LVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKHI 177

Query: 346 YILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIH 405
           Y+L++ L+      L      PK GLLM +L IIF NGN  +E  +W+V   +GL  GI 
Sbjct: 178 YVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGIE 237

Query: 406 HSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQK 465
           H +FG+ +KL+T + VK+ YL+Y +VPNS+PP Y+F WG R++ ETSKMKVL+F  KV  
Sbjct: 238 HFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVND 297

Query: 466 KDPKEWAAQYREAM-EADLKAAAEAAAEAKARAEIRAR 502
             P E++  Y EA+ + + +A A  AA+A+  A   AR
Sbjct: 298 TAPSEFSNWYTEALQDEEERARARVAAKARVSATAGAR 335


>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
          Length = 346

 Score =  184 bits (467), Expect = 2e-46
 Identities = 117/336 (34%), Positives = 170/336 (50%), Gaps = 12/336 (3%)

Query: 170 PKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWA-RR 228
           P+ +  K R  +        + D      T   +  S +  +S+ R  +   +AF   + 
Sbjct: 2   PRGQKSKLRAREKRQRTRGQTQDLKVGQPTAAEKEESPSSSSSVLRDTASSSLAFGIPQE 61

Query: 229 ASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK 288
             R      A  A+    S K    +    A+  Q+S   E         L  +   LV+
Sbjct: 62  PQREPPTTSAAAAMSCTGSDKGDESQDEENASSSQASTSTERSLKDS---LTRKTKMLVQ 118

Query: 289 YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYIL 348
           +LL K + K P  +++MLK I K+Y + +PEI  +     E VFG+ LKE++   H YIL
Sbjct: 119 FLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQRTELVFGLALKEVNPTTHSYIL 178

Query: 349 LSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSL 408
           +S L P D G   +    P+ GLLM LLS+IF+NGN + E  IWE L  LG+  G  H +
Sbjct: 179 VSMLGPND-GNQSSAWTLPRNGLLMPLLSVIFLNGNCAREEEIWEFLNMLGIYDGKRHLI 237

Query: 409 FGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDP 468
           FG+ +KLIT + V++KYL+Y +VPNS+PP Y+F WG R++ ETSKMKVL+F  KV    P
Sbjct: 238 FGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTTP 297

Query: 469 KEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMG 504
             +   Y EA+        +    A AR  + AR G
Sbjct: 298 NNFPLLYEEALR-------DEEERAGARPRVAARRG 326


>gi|222418639 melanoma antigen family B, 2 [Homo sapiens]
          Length = 319

 Score =  183 bits (464), Expect = 5e-46
 Identities = 110/322 (34%), Positives = 181/322 (56%), Gaps = 19/322 (5%)

Query: 169 RPKVKAKKAR-KVKHLDGEEDGSSDQSQA---SGTTGGRRVSKALMASMARRASRGPIAF 224
           R + K +KAR + + L+  +   +++ +A   S +  G   S +  A + +   R P   
Sbjct: 10  RAREKRRKARDETRGLNVPQVTEAEEEEAPCCSSSVSGGAASSSPAAGIPQEPQRAPTT- 68

Query: 225 WARRASRTRLAAWARRALLSLRSPK-ARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRA 283
                     AA A   + S +S K A+  +  + A+  Q+S   ++P       L  ++
Sbjct: 69  ----------AAAAAAGVSSTKSKKGAKSHQGEKNASSSQASTSTKSPSEDP---LTRKS 115

Query: 284 NDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKND 343
             LV++LL K + K  + + +MLK + K + + +PEI+++A   L  VFG++L +++ N 
Sbjct: 116 GSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILKKASEGLSVVFGLELNKVNPNG 175

Query: 344 HLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPG 403
           H Y  +  ++ TD   L ++ D P+  LLM LL +IF+NGN ++E  IWE L  LG+  G
Sbjct: 176 HTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLNGNSATEEEIWEFLNMLGVYDG 235

Query: 404 IHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKV 463
             HS+FG+  KLIT + V++KYL+Y +VP+S+PP ++F WG R+Y ETSKMKVL+F  KV
Sbjct: 236 EEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFLWGPRAYAETSKMKVLEFLAKV 295

Query: 464 QKKDPKEWAAQYREAMEADLKA 485
               P  +   Y EA++ + KA
Sbjct: 296 NGTTPCAFPTHYEEALKDEEKA 317


>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
          Length = 346

 Score =  180 bits (456), Expect = 4e-45
 Identities = 91/210 (43%), Positives = 137/210 (65%), Gaps = 1/210 (0%)

Query: 282 RANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDK 341
           + N LV++L+   + K PI ++DMLK + K + + +PEI+++A +++E VFG+ LK++D 
Sbjct: 114 KTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKVDS 173

Query: 342 NDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLR 401
               Y+L+S ++  + G +   +  PK GLL+ LL +IFM GN ++E  IWE L K+ + 
Sbjct: 174 TKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMRIY 233

Query: 402 PGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFAC 461
            G  H +FG+ +KLIT + VK KYL+Y +VPNSNP  YEF WG R++ ETSKMKVL+F  
Sbjct: 234 DGKKHFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEFWA 293

Query: 462 KVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
           KV K  P  +   Y EA+  D +   +AAA
Sbjct: 294 KVNKTVPSAFQFWYEEALR-DEEERVQAAA 322


>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
          Length = 324

 Score =  179 bits (454), Expect = 7e-45
 Identities = 105/246 (42%), Positives = 144/246 (58%), Gaps = 19/246 (7%)

Query: 264 SSQEPEAPP--------PRDVAL--LQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEY 313
           S+QE E  P        PR+V    L  +   LV ++L K Q K PI ++DMLK IIK+ 
Sbjct: 88  SNQEEEDSPSSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDD 147

Query: 314 TDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLM 373
              + EI+ RA   LE +FG+ + E+D   H Y L   L  T  G+L   K  PK GLL+
Sbjct: 148 ESHFSEILLRASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLI 207

Query: 374 VLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPN 433
           ++L +IFM GNR++E  +WEVL   G+  G  H +FG+ + LIT +FVK+KYL+Y +V N
Sbjct: 208 IVLGVIFMKGNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVAN 267

Query: 434 SNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEA 493
           S+P  YEF WG R+  ETSKMKVL+F  KV    P  + +QY EA++ +         E 
Sbjct: 268 SDPARYEFLWGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEE---------EE 318

Query: 494 KARAEI 499
           +ARA I
Sbjct: 319 RARARI 324


>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
          Length = 343

 Score =  176 bits (447), Expect = 4e-44
 Identities = 98/257 (38%), Positives = 146/257 (56%), Gaps = 4/257 (1%)

Query: 247 SPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDML 306
           S  +  G + +    L SS+E E         L  +   LV +LL K +TK PI + DM+
Sbjct: 78  SCSSNEGASSQDEKSLGSSREAEGWKEDP---LNKKVVSLVHFLLQKYETKEPITKGDMI 134

Query: 307 KDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDS 366
           K +I++    + EI++RA   +E   G+ LKE+D   H Y   S L+ T        +  
Sbjct: 135 KFVIRKDKCHFNEILKRASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKI 194

Query: 367 PKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYL 426
           PK GLLM+ L +IF+NGNR+ E  +WE++  +G+     H L+GD +K++T + V+ KYL
Sbjct: 195 PKTGLLMIALGVIFLNGNRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKDLVQLKYL 254

Query: 427 DYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAM-EADLKA 485
           +Y +VPNS+PP YEF WG R++ ETSKMKVL+F  K+    P  + + Y EA+ + + + 
Sbjct: 255 EYQQVPNSDPPRYEFLWGPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEEQRT 314

Query: 486 AAEAAAEAKARAEIRAR 502
            A AAA A   A   AR
Sbjct: 315 QARAAARAHTAAMANAR 331


>gi|169216977 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  176 bits (446), Expect = 6e-44
 Identities = 116/332 (34%), Positives = 178/332 (53%), Gaps = 9/332 (2%)

Query: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRAS--RGPIAFWA 226
           R +   ++AR+ +     ED     +QA+     +  S +  A  +   S     I   +
Sbjct: 124 RGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNAGIPQES 183

Query: 227 RRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDL 286
           +RAS     A A     S    K ++G++        S   P +       LL  +  +L
Sbjct: 184 QRASYPSSPASAVSLTSSDEGAKGQKGESPN------SFHGPSSSESTGRDLLNTKTGEL 237

Query: 287 VKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLY 346
           V++LL K   K PI R  MLK I ++Y   +PEI+ R+  ++E VFG+ LKE+D +   Y
Sbjct: 238 VQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSY 297

Query: 347 ILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHH 406
           +L+  L+  + G L      P  GLLMVLLS IFM+GNR++E  +WE L  LG+  G  H
Sbjct: 298 VLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKH 357

Query: 407 SLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKK 466
            ++G+ ++L+T + V++ YL+Y +VP+S+PP YEF WG R+  ETSKMKVL+F  K+   
Sbjct: 358 FIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDT 417

Query: 467 DPKEWAAQYREAM-EADLKAAAEAAAEAKARA 497
               + ++Y EA+ E + +A A A A   ARA
Sbjct: 418 VASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|169216191 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  176 bits (446), Expect = 6e-44
 Identities = 116/332 (34%), Positives = 178/332 (53%), Gaps = 9/332 (2%)

Query: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRAS--RGPIAFWA 226
           R +   ++AR+ +     ED     +QA+     +  S +  A  +   S     I   +
Sbjct: 124 RGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNAGIPQES 183

Query: 227 RRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDL 286
           +RAS     A A     S    K ++G++        S   P +       LL  +  +L
Sbjct: 184 QRASYPSSPASAVSLTSSDEGAKGQKGESPN------SFHGPSSSESTGRDLLNTKTGEL 237

Query: 287 VKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLY 346
           V++LL K   K PI R  MLK I ++Y   +PEI+ R+  ++E VFG+ LKE+D +   Y
Sbjct: 238 VQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSY 297

Query: 347 ILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHH 406
           +L+  L+  + G L      P  GLLMVLLS IFM+GNR++E  +WE L  LG+  G  H
Sbjct: 298 VLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKH 357

Query: 407 SLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKK 466
            ++G+ ++L+T + V++ YL+Y +VP+S+PP YEF WG R+  ETSKMKVL+F  K+   
Sbjct: 358 FIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDT 417

Query: 467 DPKEWAAQYREAM-EADLKAAAEAAAEAKARA 497
               + ++Y EA+ E + +A A A A   ARA
Sbjct: 418 VASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|169216802 PREDICTED: melanoma antigen family B, 17 [Homo
           sapiens]
          Length = 457

 Score =  176 bits (446), Expect = 6e-44
 Identities = 116/332 (34%), Positives = 178/332 (53%), Gaps = 9/332 (2%)

Query: 169 RPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRAS--RGPIAFWA 226
           R +   ++AR+ +     ED     +QA+     +  S +  A  +   S     I   +
Sbjct: 124 RGQASKRRAREKRRQARGEDQCLGGAQATAAEKEKLPSSSSPACQSPPQSFPNAGIPQES 183

Query: 227 RRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDL 286
           +RAS     A A     S    K ++G++        S   P +       LL  +  +L
Sbjct: 184 QRASYPSSPASAVSLTSSDEGAKGQKGESPN------SFHGPSSSESTGRDLLNTKTGEL 237

Query: 287 VKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLY 346
           V++LL K   K PI R  MLK I ++Y   +PEI+ R+  ++E VFG+ LKE+D +   Y
Sbjct: 238 VQFLLNKYIRKEPITREAMLKVINRKYKQHFPEILRRSTENVEVVFGLYLKEMDPSRQSY 297

Query: 347 ILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHH 406
           +L+  L+  + G L      P  GLLMVLLS IFM+GNR++E  +WE L  LG+  G  H
Sbjct: 298 VLVGKLDFPNQGSLSDGGGFPLSGLLMVLLSTIFMHGNRATEEEMWECLNALGMYKGRKH 357

Query: 407 SLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKK 466
            ++G+ ++L+T + V++ YL+Y +VP+S+PP YEF WG R+  ETSKMKVL+F  K+   
Sbjct: 358 FIYGEPQELVTKDLVREGYLEYQQVPSSDPPRYEFLWGPRARAETSKMKVLEFVAKLNDT 417

Query: 467 DPKEWAAQYREAM-EADLKAAAEAAAEAKARA 497
               + ++Y EA+ E + +A A A A   ARA
Sbjct: 418 VASTYKSRYEEALREEEEQARARAVARDSARA 449


>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  176 bits (446), Expect = 6e-44
 Identities = 89/237 (37%), Positives = 144/237 (60%), Gaps = 9/237 (3%)

Query: 264 SSQEPEAPPPRDV---------ALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYT 314
           SSQ+ E+P    V         + +  +  DLV++LL K Q K PI ++++L+ +IK Y 
Sbjct: 110 SSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYE 169

Query: 315 DVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMV 374
           D +P +   A   +  VFGI +KE+D   H ++L+++L  T  G+L   +  PK G+L++
Sbjct: 170 DHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILIL 229

Query: 375 LLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNS 434
           +LSIIF+ G  + E VIWE L  +GL  G+ H ++G+ +KL+T ++V++ YL+Y +VP S
Sbjct: 230 ILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGS 289

Query: 435 NPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
           +P  YEF WG R++ E  KM +LKF  KV   DP+ +   Y EA++ + + A +  A
Sbjct: 290 DPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIA 346


>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
          Length = 369

 Score =  176 bits (446), Expect = 6e-44
 Identities = 89/237 (37%), Positives = 144/237 (60%), Gaps = 9/237 (3%)

Query: 264 SSQEPEAPPPRDV---------ALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYT 314
           SSQ+ E+P    V         + +  +  DLV++LL K Q K PI ++++L+ +IK Y 
Sbjct: 110 SSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIKNYE 169

Query: 315 DVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMV 374
           D +P +   A   +  VFGI +KE+D   H ++L+++L  T  G+L   +  PK G+L++
Sbjct: 170 DHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILIL 229

Query: 375 LLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNS 434
           +LSIIF+ G  + E VIWE L  +GL  G+ H ++G+ +KL+T ++V++ YL+Y +VP S
Sbjct: 230 ILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGS 289

Query: 435 NPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAA 491
           +P  YEF WG R++ E  KM +LKF  KV   DP+ +   Y EA++ + + A +  A
Sbjct: 290 DPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIA 346


>gi|29171711 melanoma antigen family B, 1 [Homo sapiens]
          Length = 347

 Score =  175 bits (444), Expect = 9e-44
 Identities = 97/265 (36%), Positives = 152/265 (57%), Gaps = 10/265 (3%)

Query: 238 ARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTK 297
           A  A+    S +  + +    A+  Q++   E+     VA   G    L+ ++L K + +
Sbjct: 70  AAAAVSCTESDEGAKCQGEENASFSQATTSTESSVKDPVAWEAGM---LMHFILRKYKMR 126

Query: 298 IPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDA 357
            PI ++DMLK + ++Y D + EI+  A   LE VFG+ LKE + + H Y L+S L  T+ 
Sbjct: 127 EPIMKADMLKVVDEKYKDHFTEILNGASRRLELVFGLDLKEDNPSGHTYTLVSKLNLTND 186

Query: 358 GILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLIT 417
           G L    D P+ GLLM LL +IF+ GN ++E  IW+ +  LG   G  H ++G+ +K IT
Sbjct: 187 GNLSNDWDFPRNGLLMPLLGVIFLKGNSATEEEIWKFMNVLGAYDGEEHLIYGEPRKFIT 246

Query: 418 DEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYRE 477
            + V++KYL Y +VPNS+PP Y+F WG R+Y ET+KMKVL+F  K+    P+++ + Y E
Sbjct: 247 QDLVQEKYLKYEQVPNSDPPRYQFLWGPRAYAETTKMKVLEFLAKMNGATPRDFPSHYEE 306

Query: 478 AMEADLKAAAEAAAEAKARAEIRAR 502
           A+        +    A+ R+ +RAR
Sbjct: 307 ALR-------DEEERAQVRSSVRAR 324


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.123    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,600,002
Number of Sequences: 37866
Number of extensions: 882080
Number of successful extensions: 7832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 5985
Number of HSP's gapped (non-prelim): 2016
length of query: 606
length of database: 18,247,518
effective HSP length: 108
effective length of query: 498
effective length of database: 14,157,990
effective search space: 7050679020
effective search space used: 7050679020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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