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Search of human proteins with 28872725
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens] 808 0.0
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ... 114 1e-25
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ... 114 2e-25
gi|38373690 COP9 signalosome subunit 4 [Homo sapiens] 39 0.007
gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens] 39 0.007
gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens] 39 0.007
gi|52485606 formin-like 2 [Homo sapiens] 34 0.29
gi|81295809 pericentrin [Homo sapiens] 33 0.49
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 33 0.49
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 33 0.64
gi|32698688 citron [Homo sapiens] 32 0.83
gi|31542661 transmembrane protein 57 [Homo sapiens] 32 0.83
gi|38788380 dehydrogenase E1 and transketolase domain containing... 32 1.4
gi|194239731 eukaryotic translation elongation factor 1 delta is... 31 1.9
gi|194239727 eukaryotic translation elongation factor 1 delta is... 31 1.9
gi|194239725 eukaryotic translation elongation factor 1 delta is... 31 1.9
gi|194239723 eukaryotic translation elongation factor 1 delta is... 31 1.9
gi|25453472 eukaryotic translation elongation factor 1 delta iso... 31 1.9
gi|25453474 eukaryotic translation elongation factor 1 delta iso... 31 1.9
gi|194239729 eukaryotic translation elongation factor 1 delta is... 31 1.9
gi|25777612 proteasome 26S non-ATPase subunit 3 [Homo sapiens] 31 1.9
gi|157412259 notch1-induced protein isoform a [Homo sapiens] 30 3.2
gi|157671913 notch1-induced protein isoform b [Homo sapiens] 30 3.2
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 30 3.2
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 30 3.2
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 30 3.2
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 30 4.1
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 30 4.1
gi|11136628 eukaryotic translation elongation factor 1 beta 2 [H... 30 4.1
gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Ho... 30 4.1
>gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]
Length = 422
Score = 808 bits (2087), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKT 60
MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKT
Sbjct: 1 MAAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKT 60
Query: 61 GQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSE 120
GQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSE
Sbjct: 61 GQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSE 120
Query: 121 KRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHAL 180
KRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHAL
Sbjct: 121 KRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHAL 180
Query: 181 SNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYD 240
SNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYD
Sbjct: 181 SNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYD 240
Query: 241 SIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLA 300
SIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLA
Sbjct: 241 SIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLA 300
Query: 301 DFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKAD 360
DFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKAD
Sbjct: 301 DFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKAD 360
Query: 361 VERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKK 420
VERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKK
Sbjct: 361 VERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKK 420
Query: 421 LT 422
LT
Sbjct: 421 LT 422
>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
isoform 2 [Homo sapiens]
Length = 450
Score = 114 bits (286), Expect = 1e-25
Identities = 102/387 (26%), Positives = 177/387 (45%), Gaps = 34/387 (8%)
Query: 4 AAVVEFQRAQSLLSTDREASIDILHSIVKRDIQ-ENDEEAVQVKEQSILELGSLLAKTGQ 62
AA+ FQ+ L E L ++K + + N E + +Q + + S + +
Sbjct: 49 AALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYS 108
Query: 63 AAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKR 122
+ +L Y+ S SK + L + +DL + T LE ++ AK+++
Sbjct: 109 EKSINSILDYI-----STSKQNSDFLCQ--MDLLQEFYETT-------LEALKDAKNDRL 154
Query: 123 TFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDK------ALLVEVQLLESKT 176
F +L LY + + Y + + QL + + D + L+E+ LE +
Sbjct: 155 WF---KTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQM 211
Query: 177 YHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAF 236
Y A N K +A + +AI P + + G +H E +++ A++ F+EAF
Sbjct: 212 YTAQKNNKKLKALYEQSLHIKSAIP-HPLIMGVIRECGGKMHL-REGEFEKAHTDFFEAF 269
Query: 237 EGYDSIDSPKAITSLKYMLLCKIMLNT---PEDVQALVSGKLALRYAGRQTEALKCVAQA 293
+ YD SP+ T LKY++L +++ + P D Q K + A+ + A
Sbjct: 270 KNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYK-----NDPEILAMTNLVSA 324
Query: 294 SKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSL 353
+N + +FEK L + + DDP I H+ +L N+ Q LI++I+P++R+ I IS
Sbjct: 325 YQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKE 384
Query: 354 IKLSKADVERKLSQMILDKKFHGILDQ 380
+ + ADVE L Q ILD HG +DQ
Sbjct: 385 LNIDVADVESLLVQCILDNTIHGRIDQ 411
>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
isoform 1 [Homo sapiens]
Length = 443
Score = 114 bits (284), Expect = 2e-25
Identities = 90/325 (27%), Positives = 157/325 (48%), Gaps = 28/325 (8%)
Query: 69 LLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLE----CIEWAKSEKRTF 124
LL Y+R +++++ + + + S+LD +T ++++L E +E K K
Sbjct: 95 LLTYIR---SAVTRNYSEKSINSILDYI-----STSKQMDLLQEFYETTLEALKDAKNDR 146
Query: 125 LRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDK------ALLVEVQLLESKTYH 178
L +L LY + + Y + + QL + + D + L+E+ LE + Y
Sbjct: 147 LWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYT 206
Query: 179 ALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEG 238
A N K +A + +AI P + + G +H E +++ A++ F+EAF+
Sbjct: 207 AQKNNKKLKALYEQSLHIKSAIP-HPLIMGVIRECGGKMHL-REGEFEKAHTDFFEAFKN 264
Query: 239 YDSIDSPKAITSLKYMLLCKIMLNT---PEDVQALVSGKLALRYAGRQTEALKCVAQASK 295
YD SP+ T LKY++L +++ + P D Q K + A+ + A +
Sbjct: 265 YDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYK-----NDPEILAMTNLVSAYQ 319
Query: 296 NRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIK 355
N + +FEK L + + DDP I H+ +L N+ Q LI++I+P++R+ I IS +
Sbjct: 320 NNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELN 379
Query: 356 LSKADVERKLSQMILDKKFHGILDQ 380
+ ADVE L Q ILD HG +DQ
Sbjct: 380 IDVADVESLLVQCILDNTIHGRIDQ 404
>gi|38373690 COP9 signalosome subunit 4 [Homo sapiens]
Length = 406
Score = 39.3 bits (90), Expect = 0.007
Identities = 22/88 (25%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
Query: 330 LLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFD 389
++E NL+ + ++ + E + +L+++ A E+ SQMI + + +G +DQ +G+ + F+
Sbjct: 304 VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGI-VHFE 362
Query: 390 EPPVDKTYEAALETIQNMSKVVDSLYNK 417
T++ + IQ++ V++L K
Sbjct: 363 TREALPTWD---KQIQSLCFQVNNLLEK 387
>gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]
Length = 491
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/236 (17%), Positives = 87/236 (36%)
Query: 166 LVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDW 225
+++V + H LS + KA + A + L +G+ A K
Sbjct: 205 VIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGLAELAARKYK 264
Query: 226 KTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTE 285
+ A +F+ D + Y LC + +++Q V + +
Sbjct: 265 QAAKCLLLASFDHCDFPELLSPSNVAIYGGLCALATFDRQELQRNVISSSSFKLFLELEP 324
Query: 286 ALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRV 345
++ + A K L + + L D ++ H+ LY + + LI+ P+
Sbjct: 325 QVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSA 384
Query: 346 QIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAAL 401
+ +++ + A +E +L+Q+IL+ +D +L D T+E +L
Sbjct: 385 DMHRMAAAFNTTVAALEDELTQLILEGLISARVDSHSKILYARDVDQRSTTFEKSL 440
>gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]
Length = 527
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/236 (17%), Positives = 87/236 (36%)
Query: 166 LVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDW 225
+++V + H LS + KA + A + L +G+ A K
Sbjct: 241 VIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKLKCAAGLAELAARKYK 300
Query: 226 KTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTE 285
+ A +F+ D + Y LC + +++Q V + +
Sbjct: 301 QAAKCLLLASFDHCDFPELLSPSNVAIYGGLCALATFDRQELQRNVISSSSFKLFLELEP 360
Query: 286 ALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRV 345
++ + A K L + + L D ++ H+ LY + + LI+ P+
Sbjct: 361 QVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSA 420
Query: 346 QIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAAL 401
+ +++ + A +E +L+Q+IL+ +D +L D T+E +L
Sbjct: 421 DMHRMAAAFNTTVAALEDELTQLILEGLISARVDSHSKILYARDVDQRSTTFEKSL 476
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 33.9 bits (76), Expect = 0.29
Identities = 37/178 (20%), Positives = 78/178 (43%), Gaps = 21/178 (11%)
Query: 208 ATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDV 267
A++ + ++H+ E+ +++ Y + + +D K S K + + L+ DV
Sbjct: 319 ASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDV 378
Query: 268 QALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLY 327
AL L A + AL+ V + +N ++ + L D E + + +L
Sbjct: 379 GAL------LEDAETKNAALERVEELEEN--ISHLSEKLQDTENEAM------SKIVELE 424
Query: 328 DNLLEQN----LIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQG 381
L+++N ++R I + Q+ + ++K + ++R Q L+KK H + QG
Sbjct: 425 KQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQR---QSTLEKKIHELEKQG 479
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 33.1 bits (74), Expect = 0.49
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
Query: 27 LHSIVKRDIQENDEEAVQV--KEQSILELGSLLAKTGQAAELG-------GLLKYVRPFL 77
+HS +++ +EE QV K Q +LE L ++ AEL G L+ +
Sbjct: 1287 IHSRFEKEFSFKNEETAQVVRKHQELLEC--LKEESAAKAELALELHKTQGTLEGFKVET 1344
Query: 78 NSISKAKAA------RLVRSLLDLFLDMEAATGQEVELCLECIE-WAKSEKRTFLRQALE 130
+ + A RLV L L ++ A ++ L EC W++ E +A E
Sbjct: 1345 ADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEARE 1404
Query: 131 ARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALS 181
A L D + Q R+ + D ALL ++++LES+ LS
Sbjct: 1405 AALRKEVEDLTKEQSET-------RKQAEKDRSALLSQMKILESELEEQLS 1448
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 33.1 bits (74), Expect = 0.49
Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 23/233 (9%)
Query: 11 RAQSLLSTDREASIDILHSIV---KRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELG 67
RA + + +++ HSI+ K +Q E A+ + EQ +LG LLA T + +L
Sbjct: 278 RASAARVGQLQEALNERHSIINALKAKLQMT-EAALALSEQKAQDLGELLA-TAEQEQLS 335
Query: 68 GLLKYVRPFLNSISKA--KAARLVRSL-----LDLFLDMEAATGQEVELCLECIEWAKSE 120
+ + +A + ++L+R L +L L + + C + + +
Sbjct: 336 LSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQ 395
Query: 121 KRTFLRQALEARLVS----LYFDTKRYQEALHLGSQL-LRELKKM------DDKALLVEV 169
+ T + L+ R + L + +R +++L L ++E++ M +KA+ V
Sbjct: 396 EMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERV 455
Query: 170 QLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEE 222
Q LE+ L + +AA S R A K QA L+ Q + H ++
Sbjct: 456 QRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDK 508
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 32.7 bits (73), Expect = 0.64
Identities = 65/306 (21%), Positives = 121/306 (39%), Gaps = 30/306 (9%)
Query: 127 QALEARLVSLYFDTKRYQEALHLGSQLLRELKKMD-DKALLVEVQLLESKTYHALSNLPK 185
+ALE + S Y K+Y E + + K++D + + E LL + Y + N
Sbjct: 288 EALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANA 347
Query: 186 ARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSP 245
A+ L + A KL+A ++ G ++ +++ + + A ID P
Sbjct: 348 AKPDLDKVISLKEA---NVKLRANALIKRGSMYMQQQQPLLSTQDFNMAA-----DID-P 398
Query: 246 KAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVA---QASKNRSLADF 302
+ + KI+L+ E+ A + LR +A KC A QA + +
Sbjct: 399 QNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQI 458
Query: 303 EKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVE 362
+ A+ + ++ P + A L +Q + F + E I L +
Sbjct: 459 QAAMKGFEEVIKKFPRCAEGYALYAQALTDQ------QQFGKAD-EMYDKCIDLEPDNAT 511
Query: 363 RKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETI-------QNMSKVVDSLY 415
+ + +L ++ LD+ G+ +I +D + A ET+ NM K +D ++
Sbjct: 512 TYVHKGLLQLQWKQDLDR--GLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAID-MF 568
Query: 416 NKAKKL 421
NKA L
Sbjct: 569 NKAINL 574
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 32.3 bits (72), Expect = 0.83
Identities = 51/218 (23%), Positives = 87/218 (39%), Gaps = 25/218 (11%)
Query: 21 EASIDILHSIVKRDIQEND--EEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
E I +L + +K+D+ + + E +Q E+ E G +L++ Q A + + +R
Sbjct: 722 EEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSE--QKAMINAMDSKIRSLEQ 779
Query: 79 SISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQA--LEARLVSL 136
I + A + + LF T + ++ E I + +K QA LEA+ L
Sbjct: 780 RIVELSEANKLAANSSLF------TQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKL 833
Query: 137 YFDTKRYQEALHLGSQLLRELK-------------KMDDKALLVEVQLLESKTYHALSNL 183
++ H L EL+ K++ K L E+QL + L+ L
Sbjct: 834 EEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTAL 893
Query: 184 PKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAE 221
ARAAL S A +A ++Q+ H E
Sbjct: 894 QAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDE 931
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 32.3 bits (72), Expect = 0.83
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 78 NSISKAKA-ARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTF-----LRQALEA 131
N +SK A RL + + L D++A+ E EL + + +E+ LRQ E
Sbjct: 375 NQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENEL 434
Query: 132 RLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALT 191
L+ + Q+ SQL ++LK + VE QL+E K L ARA
Sbjct: 435 LQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAF 494
Query: 192 SA 193
+A
Sbjct: 495 AA 496
>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
[Homo sapiens]
Length = 919
Score = 31.6 bits (70), Expect = 1.4
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 25/162 (15%)
Query: 131 ARLVSLYFDTKRYQ---EALHLGSQLLRELKKMDDKALLVEVQLLESKTYHA-LSNLPKA 186
ARLV++Y + L G LL + ++ +AL VQ L+ + A L N+ K
Sbjct: 57 ARLVTVYCEHGHKAAKINPLFTGQALLENVPEI--QAL---VQTLQGPFHTAGLLNMGKE 111
Query: 187 RAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPK 246
A+L N IYC + +++ + + +EKDW F + FE +
Sbjct: 112 EASLEEVLVYLNQIYC-----GQISIETSQLQSQDEKDW------FAKRFEELQK----E 156
Query: 247 AITSLKYMLLCKIMLNTPE-DVQALVSGKLALRYAGRQTEAL 287
T+ + L K+ML + E D RY G E++
Sbjct: 157 TFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESM 198
>gi|194239731 eukaryotic translation elongation factor 1 delta
isoform 2 [Homo sapiens]
Length = 281
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 152 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 207
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 208 ETDMAQLEACVRSI 221
>gi|194239727 eukaryotic translation elongation factor 1 delta
isoform 2 [Homo sapiens]
Length = 281
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 152 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 207
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 208 ETDMAQLEACVRSI 221
>gi|194239725 eukaryotic translation elongation factor 1 delta
isoform 3 [Homo sapiens]
Length = 646
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 517 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 572
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 573 ETDMAQLEACVRSI 586
>gi|194239723 eukaryotic translation elongation factor 1 delta
isoform 1 [Homo sapiens]
Length = 647
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 518 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 573
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 574 ETDMAQLEACVRSI 587
>gi|25453472 eukaryotic translation elongation factor 1 delta
isoform 2 [Homo sapiens]
Length = 281
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 152 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 207
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 208 ETDMAQLEACVRSI 221
>gi|25453474 eukaryotic translation elongation factor 1 delta
isoform 1 [Homo sapiens]
Length = 647
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 518 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 573
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 574 ETDMAQLEACVRSI 587
>gi|194239729 eukaryotic translation elongation factor 1 delta
isoform 4 [Homo sapiens]
Length = 257
Score = 31.2 bits (69), Expect = 1.9
Identities = 20/74 (27%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 19 DREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLN 78
D + ID+ S D +E D+EA Q++E+ + + AK +L V+P+ +
Sbjct: 128 DEDDDIDLFGS----DNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDD 183
Query: 79 SISKAKAARLVRSL 92
A+ VRS+
Sbjct: 184 ETDMAQLEACVRSI 197
>gi|25777612 proteasome 26S non-ATPase subunit 3 [Homo sapiens]
Length = 534
Score = 31.2 bits (69), Expect = 1.9
Identities = 79/435 (18%), Positives = 167/435 (38%), Gaps = 50/435 (11%)
Query: 27 LHSIVKRDIQEND---EEAVQVKE-QSILELGSLLAKTGQAAELGGLLKYVRPFLNSISK 82
L ++ DI+E+ E+AV KE + +L +L T + L K V+ F S +
Sbjct: 67 LDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVQGFFTSNNA 126
Query: 83 AKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKR 142
R L FL+ T +++ + A + + L+ +V ++KR
Sbjct: 127 T------RDFLLPFLEEPMDTEADLQFRPRTGKAASTPLLPEVEAYLQLLVVIFMMNSKR 180
Query: 143 YQEALHLGSQLLRELKKMDDKAL---LVEVQLLESKTYHALSNLPKARAALTSARTTANA 199
Y+EA + L++++ + +AL + ++ Y L L R+ L + TA
Sbjct: 181 YKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATL 240
Query: 200 IYCPPKLQATLDM-------------------QSGIIHAAEEKDWKTAYSYFYEAFEGY- 239
+ L++ +S A +W Y Y+ +
Sbjct: 241 RHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEW-ARYLYYTGRIKAIQ 299
Query: 240 -----------DSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALK 288
+++ T++ + +L E + + +L R + +
Sbjct: 300 LEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMP 359
Query: 289 --CVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQ 346
+ QA + +LA F + L + + + D T + +L N+++ + + +SR+
Sbjct: 360 YFLLTQAVRTGNLAKFNQVLDQFGEKFQADGTY-TLIIRLRHNVIKTGVRMISLSYSRIS 418
Query: 347 IEHISSLIKL-SKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQ 405
+ I+ ++L S D E +++ I D ++ +G + + + T E L Q
Sbjct: 419 LADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMIDIYSTREPQLAFHQ 478
Query: 406 NMSKVVDSLYNKAKK 420
+S +D ++N + K
Sbjct: 479 RISFCLD-IHNMSVK 492
>gi|157412259 notch1-induced protein isoform a [Homo sapiens]
Length = 451
Score = 30.4 bits (67), Expect = 3.2
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 17/103 (16%)
Query: 8 EFQRAQSLLSTDREASIDILHSIV-----------------KRDIQENDEEAVQVKEQSI 50
+FQ Q LLS E+S+ IL+ +V ++ + E A +VKE++I
Sbjct: 347 DFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVKERNI 406
Query: 51 LELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLL 93
L G L++ +L L+ + S+ K + + L+ LL
Sbjct: 407 LLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLL 449
>gi|157671913 notch1-induced protein isoform b [Homo sapiens]
Length = 401
Score = 30.4 bits (67), Expect = 3.2
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 17/103 (16%)
Query: 8 EFQRAQSLLSTDREASIDILHSIV-----------------KRDIQENDEEAVQVKEQSI 50
+FQ Q LLS E+S+ IL+ +V ++ + E A +VKE++I
Sbjct: 297 DFQETQKLLSMLEESSLCILYPVVVVSVHFLDFKLVPPSQKMENLMQIREFAKEVKERNI 356
Query: 51 LELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLL 93
L G L++ +L L+ + S+ K + + L+ LL
Sbjct: 357 LLYGLLISYPQDDQKLQESLRQGAIIIASLIKERNSGLIGQLL 399
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 30.4 bits (67), Expect = 3.2
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 31/182 (17%)
Query: 19 DREASIDILHS----IVKRDIQENDE--EAVQVKEQSILELGSLLAKTGQA--AELGGLL 70
+R+A I+ + S I K +Q E ++ Q E G LL Q E LL
Sbjct: 2983 ERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLL 3042
Query: 71 KYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLR--QA 128
R L ++ A L+ L + G E + +EC++ K+++R+ L QA
Sbjct: 3043 AAFRTELTALGTTDAVGLLNCLEQRIQEQ----GVEYQAAMECLQ--KADRRSLLSEIQA 3096
Query: 129 LEARLVSLYFDTKRYQEALHLGSQLLR---------------ELKKMDDKALLVEVQLLE 173
L A++ KR QE+ +LL EL M D+A ++ QL
Sbjct: 3097 LHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSS 3156
Query: 174 SK 175
K
Sbjct: 3157 EK 3158
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 30.4 bits (67), Expect = 3.2
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 31/182 (17%)
Query: 19 DREASIDILHS----IVKRDIQENDE--EAVQVKEQSILELGSLLAKTGQA--AELGGLL 70
+R+A I+ + S I K +Q E ++ Q E G LL Q E LL
Sbjct: 2975 ERKAYINTISSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLL 3034
Query: 71 KYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLR--QA 128
R L ++ A L+ L + G E + +EC++ K+++R+ L QA
Sbjct: 3035 AAFRTELTALGTTDAVGLLNCLEQRIQEQ----GVEYQAAMECLQ--KADRRSLLSEIQA 3088
Query: 129 LEARLVSLYFDTKRYQEALHLGSQLLR---------------ELKKMDDKALLVEVQLLE 173
L A++ KR QE+ +LL EL M D+A ++ QL
Sbjct: 3089 LHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSS 3148
Query: 174 SK 175
K
Sbjct: 3149 EK 3150
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 30.4 bits (67), Expect = 3.2
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 75 PFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLV 134
P+L+ + KAA+ V L+ F+ E G+ C +C + + KR + ++ +
Sbjct: 256 PYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTL 315
Query: 135 SLYFDTKRYQEALHLGSQLLRELK 158
SL KR+ A G ++ +++K
Sbjct: 316 SL----KRF--ANFTGGKIAKDVK 333
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 30.0 bits (66), Expect = 4.1
Identities = 32/147 (21%), Positives = 59/147 (40%), Gaps = 19/147 (12%)
Query: 107 VELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALL 166
+E C ++ + + +LR+A Y DT++Y+EA+ ++ + K + K LL
Sbjct: 258 IEDCTNAVKLDDTYIKAYLRRA------QCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLL 311
Query: 167 VEVQL----LESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEE 222
QL + K Y+ + + K ++ Y L D SG ++
Sbjct: 312 KNAQLELKKSKRKDYYKILGVDK-----NASEDEIKKAYRKRALMHHPDRHSGASAEVQK 366
Query: 223 KDWKTAYSYFYEAFEGYDSIDSPKAIT 249
++ K F E E + + PK T
Sbjct: 367 EEEKK----FKEVGEAFTILSDPKKKT 389
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 30.0 bits (66), Expect = 4.1
Identities = 32/147 (21%), Positives = 59/147 (40%), Gaps = 19/147 (12%)
Query: 107 VELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALL 166
+E C ++ + + +LR+A Y DT++Y+EA+ ++ + K + K LL
Sbjct: 314 IEDCTNAVKLDDTYIKAYLRRA------QCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLL 367
Query: 167 VEVQL----LESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEE 222
QL + K Y+ + + K ++ Y L D SG ++
Sbjct: 368 KNAQLELRKSKRKDYYKILGVDK-----NASEDEIKKAYRKRALMHHPDRHSGASAEVQK 422
Query: 223 KDWKTAYSYFYEAFEGYDSIDSPKAIT 249
++ K F E E + + PK T
Sbjct: 423 EEEKK----FKEVGEAFTILSDPKKKT 445
>gi|11136628 eukaryotic translation elongation factor 1 beta 2 [Homo
sapiens]
Length = 225
Score = 30.0 bits (66), Expect = 4.1
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 17 STDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPF 76
+TD + DI + D +E EEA +++E+ + + S AK +L V+P+
Sbjct: 92 ATDSKDDDDI--DLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPW 149
Query: 77 LNSISKAKAARLVRSL 92
+ AK VRS+
Sbjct: 150 DDETDMAKLEECVRSI 165
>gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Homo
sapiens]
Length = 225
Score = 30.0 bits (66), Expect = 4.1
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 17 STDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPF 76
+TD + DI + D +E EEA +++E+ + + S AK +L V+P+
Sbjct: 92 ATDSKDDDDI--DLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPW 149
Query: 77 LNSISKAKAARLVRSL 92
+ AK VRS+
Sbjct: 150 DDETDMAKLEECVRSI 165
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,838,881
Number of Sequences: 37866
Number of extensions: 477104
Number of successful extensions: 1744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1705
Number of HSP's gapped (non-prelim): 87
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.