Search of human proteins with 28827795

Search of human proteins with 28827795

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28827795 chromatin modifying protein 4B [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28827795 chromatin modifying protein 4B [Homo sapiens]             439   e-123
gi|22748643 chromatin modifying protein 4C [Homo sapiens]             289   1e-78
gi|40548422 chromatin modifying protein 4A [Homo sapiens]             271   3e-73
gi|189409150 chromatin modifying protein 5 [Homo sapiens]              72   5e-13
gi|31542673 chromatin modifying protein 6 [Homo sapiens]               67   2e-11
gi|22748641 CHMP family, member 7 [Homo sapiens]                       64   1e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    54   8e-08
gi|40254866 chromatin modifying protein 2B [Homo sapiens]              48   8e-06
gi|4506467 radixin [Homo sapiens]                                      42   3e-04
gi|4505257 moesin [Homo sapiens]                                       41   7e-04
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       41   7e-04
gi|4504063 golgin 97 [Homo sapiens]                                    41   0.001
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              40   0.001
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    40   0.002
gi|38044112 restin isoform b [Homo sapiens]                            40   0.002
gi|4506751 restin isoform a [Homo sapiens]                             40   0.002
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    40   0.002
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]    40   0.002
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]    40   0.002
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]    40   0.002
gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]        39   0.003
gi|221139761 zinc finger protein 853 [Homo sapiens]                    39   0.005
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     39   0.005
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         39   0.005
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         39   0.005
gi|203096856 kinesin family member 7 [Homo sapiens]                    39   0.005
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     38   0.006
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    38   0.008
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    37   0.010
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog...    37   0.010

>gi|28827795 chromatin modifying protein 4B [Homo sapiens]
          Length = 224

 Score =  439 bits (1128), Expect = e-123
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK 60
           MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK
Sbjct: 1   MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK 60

Query: 61  NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
           NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH
Sbjct: 61  NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
           DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL
Sbjct: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180

Query: 181 LEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELENWAGSM 224
           LEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELENWAGSM
Sbjct: 181 LEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELENWAGSM 224


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score =  289 bits (740), Expect = 1e-78
 Identities = 147/238 (61%), Positives = 184/238 (77%), Gaps = 23/238 (9%)

Query: 1   MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK 60
           MS  GK F  GG    +  P+PQEA+ RLR+TEEML KKQE+LE +I++E+  AKKHGT+
Sbjct: 1   MSKLGKFFKGGGSSKSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQ 60

Query: 61  NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
           NKRAALQALKRKKR+EKQL QIDGTLSTIEFQREALEN++TNTEVL+NMG+AAKAMK+ H
Sbjct: 61  NKRAALQALKRKKRFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVH 120

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
           +NMD++K+D+LMQ+I +QQ++A+EIS A S+ VGFG++FDEDELMAELEELEQEEL+K +
Sbjct: 121 ENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKM 180

Query: 181 LEISGPETVPLPNVPSIALPSKPAKK-----------------KEEEDDDMKELENWA 221
             I       LPNVPS +LP++P +K                  EEEDDD+K+L  WA
Sbjct: 181 TNIR------LPNVPSSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDDIKQLAAWA 232


>gi|40548422 chromatin modifying protein 4A [Homo sapiens]
          Length = 265

 Score =  271 bits (693), Expect = 3e-73
 Identities = 139/223 (62%), Positives = 180/223 (80%), Gaps = 6/223 (2%)

Query: 1   MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTK 60
           MS  G+LFG G  + G   PTP+EAIQ+L++TE++L KKQEFLE+KI+QEL  AKK+GTK
Sbjct: 44  MSGLGRLFGKGKKEKG---PTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTK 100

Query: 61  NKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
           NKRAALQAL+RKKR+E+QLAQ DGTLST+EFQREA+ENA TN EVL+ M  AA++MK A+
Sbjct: 101 NKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAY 160

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
            +MDIDKVDELM DI +QQE+A++IS AIS+P+GFG++ DEDEL+ ELEELEQEEL + L
Sbjct: 161 QDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQEL 220

Query: 181 LEISGPE---TVPLPNVPSIALPSKPAKKKEEEDDDMKELENW 220
           L +   E   +V LP+VPS  LP+ PA K +E+++ +K+L  W
Sbjct: 221 LNVGDKEEEPSVKLPSVPSTHLPAGPAPKVDEDEEALKQLAEW 263


>gi|189409150 chromatin modifying protein 5 [Homo sapiens]
          Length = 219

 Score = 71.6 bits (174), Expect = 5e-13
 Identities = 65/217 (29%), Positives = 101/217 (46%), Gaps = 29/217 (13%)

Query: 13  GKAGKGGPTPQ--EAIQRLRDTEEMLSKKQEFLEK---KIEQELTAAKKHGTKN--KRAA 65
           GKA    P P   + I  +    E + KK   L+    K + ++   ++   KN  K+ A
Sbjct: 6   GKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA 65

Query: 66  LQALKRKKRYEKQ---LAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDN 122
           L+ LK+K+ YE+Q   LAQ    +    +  ++L++  T  + +K      K MK A+  
Sbjct: 66  LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK---LGVKEMKKAYKQ 122

Query: 123 MDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEEL---DKN 179
           + ID++++L   + D  E A EI  A+S+  G   E DED+L AEL+ L  E L   D +
Sbjct: 123 VKIDQIEDLQDQLEDMMEDANEIQEALSRSYG-TPELDEDDLEAELDALGDELLADEDSS 181

Query: 180 LLEISG-----PETVPLPN-------VPSIALPSKPA 204
            L+ +      PE VP          V    LP  PA
Sbjct: 182 YLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPA 218


>gi|31542673 chromatin modifying protein 6 [Homo sapiens]
          Length = 201

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 46/199 (23%), Positives = 97/199 (48%), Gaps = 20/199 (10%)

Query: 5   GKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRA 64
           G LFG    K         +AI +L+   + L + Q+ + +++E+E   A++     ++ 
Sbjct: 2   GNLFGR---KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKE 58

Query: 65  ALQALKRKKRYEKQLA-QIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123
             + L +KKRY++QL  + +  +S++E   +++E      +V++ + +  + +   H  M
Sbjct: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM 118

Query: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183
            I++V+ ++ +  +  E   +I   ++   G   + DED ++ EL  + QE+++      
Sbjct: 119 SIEEVERILDETQEAVEYQRQIDELLA---GSFTQEDEDAILEELSAITQEQIE------ 169

Query: 184 SGPETVPLPNVPSIALPSK 202
                  LP VPS  LP K
Sbjct: 170 -------LPEVPSEPLPEK 181


>gi|22748641 CHMP family, member 7 [Homo sapiens]
          Length = 453

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 48/189 (25%), Positives = 94/189 (49%), Gaps = 11/189 (5%)

Query: 26  IQRLRDTEEMLSKKQEFLEKKIE---QELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82
           + +L  +E++LS+K E L ++ E   +E   A + G   K+ AL++LK K+R EK++  +
Sbjct: 241 VYQLMQSEQLLSRKVESLSQEAERCKEEARRACRAG--KKQLALRSLKAKQRTEKRIEAL 298

Query: 83  DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELA 142
              L T++   + +  + T+  V         A+K +  ++ ++K + L+  I +  +  
Sbjct: 299 HAKLDTVQGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQ 358

Query: 143 EEISTAISKPVGFGEEFDEDELMAELEELEQE------ELDKNLLEISGPETVPLPNVPS 196
           +E+S  ++  V  G +FD +EL  EL+ L Q+      +L  N        +VP P +  
Sbjct: 359 DEVSQTLAGGVTNGLDFDSEELEKELDILLQDTTKEPLDLPDNPRNRHFTNSVPNPRISD 418

Query: 197 IALPSKPAK 205
             L ++  K
Sbjct: 419 AELEAELEK 427


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 53/227 (23%), Positives = 102/227 (44%), Gaps = 30/227 (13%)

Query: 14  KAGKGGPTP------QEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQ 67
           K  K GP+       QEA+ +L++ EE   +++E   K++E EL A +K   + ++   +
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE-ELEAKRKEEERLEQEKRE 388

Query: 68  ALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMG---------------YA 112
             K+K++  K+  + +G L T + QREA   A    ++L+  G               Y 
Sbjct: 389 RKKQKEKERKERLKKEGKLLT-KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYE 447

Query: 113 AKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELE 172
            K  K     ++  +V E M+  A  + + + +      P     E +ED   A L++ E
Sbjct: 448 DKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507

Query: 173 QEELDKNLLEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELEN 219
               D+   ++ G       N   I +   P +++EEE+++ ++ E+
Sbjct: 508 AMASDEETEKVEG-------NKVHIEVKENPEEEEEEEEEEEEDEES 547



 Score = 35.0 bits (79), Expect = 0.052
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 13/115 (11%)

Query: 114 KAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQ 173
           K+  +  D++D+D +   ++     +E   + S    K     ++FDED+++ ELEEL  
Sbjct: 8   KSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSL 67

Query: 174 E----ELDKNLLEISGPETVPLPNVPSIALPSK-----PAKKKEEEDDDMKELEN 219
           E    + D+  + +   E     N        K       KK+  +D+D +ELE+
Sbjct: 68  EAQGIKADRETVAVKPTEN----NEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 44/206 (21%), Positives = 79/206 (38%), Gaps = 29/206 (14%)

Query: 28  RLRDTEEMLSKKQEFLEKKIEQELTAAKKHGT-------------KNKRAALQALKRKKR 74
           R+  + E   +  EFL+ +  Q+     K G              K K  A +  ++K+R
Sbjct: 179 RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKER 238

Query: 75  YEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQD 134
             K+  +    L  ++ ++E LE         K+     ++ +   +     KV      
Sbjct: 239 ERKKRDEEKAKLRKLK-EKEELETGK------KDQSKQKESQRKFEEETVKSKVTVDTGV 291

Query: 135 IADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPE--TVPLP 192
           I   +E AE  + A     G  ++ D+ +   E EE E+E+         GP   TV   
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKK-------KGPSKATVKAM 344

Query: 193 NVPSIALPSKPAKKKEEEDDDMKELE 218
                 L  +  ++K EE++ +K LE
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLE 370


>gi|40254866 chromatin modifying protein 2B [Homo sapiens]
          Length = 213

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 48/196 (24%), Positives = 83/196 (42%), Gaps = 9/196 (4%)

Query: 23  QEAIQRLRDTEEMLSKKQEFLEKKIEQ-ELTAAKKHGTKNKRAALQALKRKKRYEKQLAQ 81
           +E  + LR T+  + + +  LEK+ +Q EL   K     NK A     K+     KQ  +
Sbjct: 15  KEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTR 74

Query: 82  IDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQEL 141
                S +       +  N+  ++   M   AK M+A +  MD  K  + MQ+   +   
Sbjct: 75  TFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMK 134

Query: 142 AEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIA--L 199
            E     I+  +   + FD  +   E +++  + LD+  +EISG     +   PS A  L
Sbjct: 135 MEMTEEMINDTL--DDIFDGSDDEEESQDIVNQVLDEIGIEISG----KMAKAPSAARSL 188

Query: 200 PSKPAKKKEEEDDDMK 215
           PS    K    D++++
Sbjct: 189 PSASTSKATISDEEIE 204


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 52/205 (25%), Positives = 85/205 (41%), Gaps = 25/205 (12%)

Query: 27  QRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTL 86
           +R  DT E+   K +  E+K +++L  A+    K KR   +  K K+R E++  ++   L
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAE--KEKERIEREKEELMERL 351

Query: 87  STIEFQ------------REALE------NANTNTEVLKNMGYAAKAMKAAHDNMDIDKV 128
             IE Q            R+ALE       A    E L+    AA+  K+A      D++
Sbjct: 352 KQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQM 411

Query: 129 DELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPET 188
               Q  A+  E   +I+          EE  E +  A      QE+L+K   E+    +
Sbjct: 412 KNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAA---QEDLEKTKEELKTVMS 468

Query: 189 VPLPNVPSIALPSKPAKKKEEEDDD 213
            P P  P   +P  P + + +E D+
Sbjct: 469 APPPPPPPPVIP--PTENEHDEHDE 491


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 42/194 (21%), Positives = 88/194 (45%), Gaps = 9/194 (4%)

Query: 27  QRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTL 86
           +R  DT E+   K +  E+K ++++  A     K KR    A K K++ E++  ++   L
Sbjct: 294 RRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKRE--MAEKEKEKIEREKEELMERL 351

Query: 87  STIE-----FQREALENANTNTEVLKNMGYA-AKAMKAAHDNMDIDKVDE-LMQDIADQQ 139
             IE      Q+E  E      E+ +    A ++A K A +  + ++  E L+Q   DQ+
Sbjct: 352 KQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQK 411

Query: 140 ELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIAL 199
           +  E+++  +++      + +      E E +E ++  + + E        L    S   
Sbjct: 412 KTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPH 471

Query: 200 PSKPAKKKEEEDDD 213
            ++PA+ +++E D+
Sbjct: 472 VAEPAENEQDEQDE 485


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 29/181 (16%)

Query: 23   QEAIQRLRDTEEMLSKK-----QEFLEKKIEQELTAAKKHGTKNKRAALQALKRK----- 72
            +EA+Q  R+ EE   K          E K EQ+ +A  +   KN    ++ L+ +     
Sbjct: 1744 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1803

Query: 73   ----KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKV 128
                K  +KQL +++  +  +E + EA +  N   E +K M  + + +K      + DK 
Sbjct: 1804 QIALKGGKKQLQKLEARVRELEGELEAEQKRNA--ESVKGMRKSERRIKELTYQTEEDKK 1861

Query: 129  DEL-MQDIADQ------------QELAEEISTAISKPVGFGEEFDEDELMAELEELEQEE 175
            + L +QD+ D+            +E  E+ +T +SK      E DE E  A++ E +  +
Sbjct: 1862 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921

Query: 176  L 176
            L
Sbjct: 1922 L 1922


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 45/193 (23%), Positives = 88/193 (45%), Gaps = 12/193 (6%)

Query: 27  QRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTL 86
           Q L   + ML KK+E L K +EQEL A  +  ++ +   + + +      ++L ++    
Sbjct: 179 QELSKIKHMLLKKEESLGK-MEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHY 237

Query: 87  STIEFQREALENANTNTE-VLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEI 145
           ST+E QR+ +  + T  E  +  +    + ++A    + ID     +Q +  + +  E++
Sbjct: 238 STLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSID-----LQKVTAETQEKEDV 292

Query: 146 STAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIALPSKPAK 205
            T + + V   E+  E  L  E E +++   +K L E +  +T        +A  S  AK
Sbjct: 293 ITHLQEKVASLEKRLEQNLSGE-EHVQELLKEKTLAEQNLEDT----RQQLLAARSSQAK 347

Query: 206 KKEEEDDDMKELE 218
                +  ++ELE
Sbjct: 348 AINTLETRVRELE 360



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 35/156 (22%), Positives = 68/156 (43%), Gaps = 17/156 (10%)

Query: 33  EEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQ 92
           EE+  +++EF ++     LTA      +N R   + L +K   E+++ Q++   ++   Q
Sbjct: 487 EEVRKQREEFQQQAAN--LTAIIDEKEQNLREKTEVLLQK---EQEILQLERGHNSALLQ 541

Query: 93  REALENANTNTEVLKNMGYAAKAMKAAHDNM---------DIDKVDELMQDIADQQELAE 143
              L+      E L+ +     A+ A  +++         +   V+E        Q+   
Sbjct: 542 IHQLQ---AELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEALSVNESHVTSRAMQDPVF 598

Query: 144 EISTAISKPVGFGEEFDEDELMAELEELEQEELDKN 179
           ++ TA   P G     D  +L  E ++LEQ+ L+KN
Sbjct: 599 QLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQLLEKN 634


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 54/216 (25%), Positives = 96/216 (44%), Gaps = 26/216 (12%)

Query: 10  AGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQAL 69
           +GGG      P+ Q   Q+L++ EEM    QE +EK  E+  T   K+     R  +  +
Sbjct: 327 SGGGMQAAAPPSSQPHPQQLQEQEEM----QEEMEKLREENETL--KNEIDELRTEMDEM 380

Query: 70  KRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH-DNMDIDKV 128
            R   +E+   Q       ++  R  LE AN N  +L+     A+  +  +    +ID  
Sbjct: 381 -RDTFFEEDACQ-------LQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEID-- 430

Query: 129 DELMQDIADQQELAEEISTAISKPVGFGEE---FDEDELMAELEELEQEELDKNLL--EI 183
            EL++ +    ++A+++S  +   +   EE     EDE     ++L + E+ K  L  E+
Sbjct: 431 GELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNEL 490

Query: 184 SGPETVPLPNVPSIALPSKPAKKK----EEEDDDMK 215
              + + L    S  LP    K +    EE+++D+K
Sbjct: 491 EKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLK 526


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 29/181 (16%)

Query: 23   QEAIQRLRDTEEMLSKK-----QEFLEKKIEQELTAAKKHGTKNKRAALQALKRK----- 72
            +EA+Q  R+ EE   K          E K EQ+ +A  +   KN    ++ L+ +     
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801

Query: 73   ----KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKV 128
                K  +KQL +++  +  +E + EA +  N   E +K M  + + +K      + D+ 
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNA--ESVKGMRKSERRIKELTYQTEEDRK 1859

Query: 129  DEL-MQDIADQ------------QELAEEISTAISKPVGFGEEFDEDELMAELEELEQEE 175
            + L +QD+ D+            +E  E+ +T +SK      E DE E  A++ E +  +
Sbjct: 1860 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1919

Query: 176  L 176
            L
Sbjct: 1920 L 1920



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 28/130 (21%), Positives = 61/130 (46%), Gaps = 9/130 (6%)

Query: 48  EQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLK 107
           E+E+ + K+  T+ K A  ++  R+K  E+++  +    + ++ Q +A ++   + E   
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905

Query: 108 NMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEF--DEDELM 165
           +     K    A       KV E+ + + D++E+  E++    K      E   D D+L 
Sbjct: 906 DQLIKNKIQLEA-------KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958

Query: 166 AELEELEQEE 175
             L ++E+E+
Sbjct: 959 LTLAKVEKEK 968


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 17   KGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYE 76
            K   + QEA ++  + ++ L +K   LEKK+E      ++   + +RA  +    K ++E
Sbjct: 939  KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSET---KTKHE 995

Query: 77   KQLAQIDGTLSTIEFQREALENANT----NTEVLKNMGYAAKAMKAAHDNMDI-----DK 127
            + L  +  TL   E + +     N+      E L+     AKA + A D M I      +
Sbjct: 996  EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1055

Query: 128  VDELMQDIADQQE----LAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
              E +  + D ++    L  E+ T     +   EE ++ + +  +E  + EE  K +
Sbjct: 1056 KTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI 1112



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 38/183 (20%)

Query: 21  TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLA 80
           T Q+ I+ L    E LSK+ E L+ K+E        H  K     +   K K   E  +A
Sbjct: 537 THQKEIKALYTATEKLSKENESLKSKLE--------HANKENSDVIALWKSK--LETAIA 586

Query: 81  QIDGTLSTIEFQ------REALENANTNTEV----------LKNMGYAAKAMKAAHDNMD 124
                +  ++         E  E A   T++          ++N+     + +AAH    
Sbjct: 587 SHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEM 646

Query: 125 IDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEE----LEQEELDKNL 180
                +LM+ I +++   E I + + K         ED+ + E+E+    L++ E+    
Sbjct: 647 EALRAKLMKVIKEKENSLEAIRSKLDKA--------EDQHLVEMEDTLNKLQEAEIKVKE 698

Query: 181 LEI 183
           LE+
Sbjct: 699 LEV 701


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 40/177 (22%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 17   KGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYE 76
            K   + QEA ++  + ++ L +K   LEKK+E      ++   + +RA  +    K ++E
Sbjct: 974  KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSET---KTKHE 1030

Query: 77   KQLAQIDGTLSTIEFQREALENANT----NTEVLKNMGYAAKAMKAAHDNMDI-----DK 127
            + L  +  TL   E + +     N+      E L+     AKA + A D M I      +
Sbjct: 1031 EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1090

Query: 128  VDELMQDIADQQE----LAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
              E +  + D ++    L  E+ T     +   EE ++ + +  +E  + EE  K +
Sbjct: 1091 KTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI 1147



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 38/183 (20%)

Query: 21  TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLA 80
           T Q+ I+ L    E LSK+ E L+ K+E        H  K     +   K K   E  +A
Sbjct: 572 THQKEIKALYTATEKLSKENESLKSKLE--------HANKENSDVIALWKSK--LETAIA 621

Query: 81  QIDGTLSTIEFQ------REALENANTNTEV----------LKNMGYAAKAMKAAHDNMD 124
                +  ++         E  E A   T++          ++N+     + +AAH    
Sbjct: 622 SHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEM 681

Query: 125 IDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEE----LEQEELDKNL 180
                +LM+ I +++   E I + + K         ED+ + E+E+    L++ E+    
Sbjct: 682 EALRAKLMKVIKEKENSLEAIRSKLDKA--------EDQHLVEMEDTLNKLQEAEIKVKE 733

Query: 181 LEI 183
           LE+
Sbjct: 734 LEV 736


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 39/222 (17%)

Query: 24   EAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNK-------------------RA 64
            +AIQR  + EE   K  + L++  E   TA  K  +  K                     
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHT 1441

Query: 65   ALQALKRKKR-YEKQLAQIDGTLSTIEFQREAL--ENANTNTEVLKNMGYAAKAMKAAHD 121
            A   L +K+R ++K LA+    L   + + EA   E+ + +TE+ K        M+ A++
Sbjct: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFK--------MRNAYE 1493

Query: 122  NMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLL 181
             +    VD+L     + + L EEIS    +    G+   E E   +L E E+ +L   L 
Sbjct: 1494 EV----VDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALE 1549

Query: 182  EISGPETVPLPNVPSIAL-----PSKPAKKKEEEDDDMKELE 218
            E+ G        +  + L      S+  +K  E+D+++++L+
Sbjct: 1550 EVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591


>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 53/223 (23%), Positives = 93/223 (41%), Gaps = 29/223 (13%)

Query: 18  GGPTPQEA-----IQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAA------- 65
           GG   Q A      Q L+D ++ L  K+  L + +E+EL   K    K ++         
Sbjct: 665 GGARSQAASILTKFQELKDVQDELRIKENEL-RALEEELAGLKNTAEKYRQLKQQWEMKT 723

Query: 66  -----LQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
                LQ   ++  Y KQ  ++D    TIE   E L+N     E+ +      + ++   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTK---EIQRKAEEKYEVLENKM 780

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELD-KN 179
            N + ++  EL +D   + + A+  + A SK +   ++ + + +  ELEEL++E    K 
Sbjct: 781 KNAEAEREREL-KDAQKKLDCAKTKADASSKKMKEKQQ-EVEAITLELEELKREHTSYKQ 838

Query: 180 LLE-----ISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKEL 217
            LE     I   E+        +A   +   K +EE    KE+
Sbjct: 839 QLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEV 881


>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 53/223 (23%), Positives = 93/223 (41%), Gaps = 29/223 (13%)

Query: 18  GGPTPQEA-----IQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAA------- 65
           GG   Q A      Q L+D ++ L  K+  L + +E+EL   K    K ++         
Sbjct: 665 GGARSQAASILTKFQELKDVQDELRIKENEL-RALEEELAGLKNTAEKYRQLKQQWEMKT 723

Query: 66  -----LQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
                LQ   ++  Y KQ  ++D    TIE   E L+N     E+ +      + ++   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTK---EIQRKAEEKYEVLENKM 780

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELD-KN 179
            N + ++  EL +D   + + A+  + A SK +   ++ + + +  ELEEL++E    K 
Sbjct: 781 KNAEAEREREL-KDAQKKLDCAKTKADASSKKMKEKQQ-EVEAITLELEELKREHTSYKQ 838

Query: 180 LLE-----ISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKEL 217
            LE     I   E+        +A   +   K +EE    KE+
Sbjct: 839 QLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEV 881


>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 53/223 (23%), Positives = 93/223 (41%), Gaps = 29/223 (13%)

Query: 18  GGPTPQEA-----IQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAA------- 65
           GG   Q A      Q L+D ++ L  K+  L + +E+EL   K    K ++         
Sbjct: 665 GGARSQAASILTKFQELKDVQDELRIKENEL-RALEEELAGLKNTAEKYRQLKQQWEMKT 723

Query: 66  -----LQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAH 120
                LQ   ++  Y KQ  ++D    TIE   E L+N     E+ +      + ++   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTK---EIQRKAEEKYEVLENKM 780

Query: 121 DNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELD-KN 179
            N + ++  EL +D   + + A+  + A SK +   ++ + + +  ELEEL++E    K 
Sbjct: 781 KNAEAEREREL-KDAQKKLDCAKTKADASSKKMKEKQQ-EVEAITLELEELKREHTSYKQ 838

Query: 180 LLE-----ISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKEL 217
            LE     I   E+        +A   +   K +EE    KE+
Sbjct: 839 QLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEV 881


>gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]
          Length = 222

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 38/179 (21%), Positives = 80/179 (44%), Gaps = 14/179 (7%)

Query: 44  EKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNT 103
           E+K+++ +  A K G K+    +   K   R  K ++++  + + +      ++N     
Sbjct: 41  EEKVKRSVKDAAKKGQKD--VCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVL 98

Query: 104 EVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDE 163
            V  ++  + + MKA    + I ++   M++++ +   A  I   +       E  D+ E
Sbjct: 99  RVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTF---ESMDDQE 155

Query: 164 LMAELEELEQEELDKNLLEISGPETVPLPNVPSIALP------SKPAKKKEEEDDDMKE 216
              E+EE  + E+D+ L EI+       P+  + ALP      +  A + EEE+++  E
Sbjct: 156 ---EMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALE 211


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 39/180 (21%), Positives = 85/180 (47%), Gaps = 14/180 (7%)

Query: 27  QRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQAL--KRKKRYEKQLAQID- 83
           Q+ +  +++L ++QE L+++ +Q+L   ++   + ++     L  + ++  E +L  +D 
Sbjct: 270 QQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDL 329

Query: 84  GTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAE 143
           G+   +E QR+ LE      E+ +        +K   +   +++  E  Q   +QQE+  
Sbjct: 330 GSEQELEQQRQELER---QQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQL 386

Query: 144 EISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIALPSKP 203
           E++     PV  G +  + E+  EL  + Q EL   L+  +G     +P  P+  + + P
Sbjct: 387 ELT-----PVELGAQ--QQEVQLELTPV-QPELQLELVPAAGGGGAAVPGAPAAVVVAPP 438



 Score = 33.5 bits (75), Expect = 0.15
 Identities = 34/196 (17%), Positives = 87/196 (44%), Gaps = 20/196 (10%)

Query: 23  QEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82
           QE +Q  +  E+ + ++QE L+++++++    ++     ++  LQ  ++ ++ + Q  Q 
Sbjct: 174 QEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQ- 232

Query: 83  DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELA 142
                 ++ Q++ L        +L+  G   + +             +L Q + +QQ+  
Sbjct: 233 ----EQLQQQQQLL--------LLQQQGQLQQQLLQQQQA-------QLQQQLLEQQQAQ 273

Query: 143 EEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIALPSK 202
            +    + +     ++  +  L  + E+L+Q++L    LE    E V L  +P      +
Sbjct: 274 LQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQ 333

Query: 203 PAKKKEEEDDDMKELE 218
             +++ +E +  +ELE
Sbjct: 334 ELEQQRQELERQQELE 349


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 37/154 (24%)

Query: 29   LRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLST 88
            L D    L+K+++ LE +I +  T   +   K+K  A    K K ++E  +  ++  L  
Sbjct: 983  LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA----KLKNKHEAMITDLEERLRR 1038

Query: 89   IEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDI-DKVDELMQDIAD-QQELAEEIS 146
             E QR+ LE      E                D+ D+ D++ EL   IA+ + +LA++  
Sbjct: 1039 EEKQRQELEKTRRKLE---------------GDSTDLSDQIAELQAQIAELKMQLAKK-- 1081

Query: 147  TAISKPVGFGEEFDEDELMAELEELEQEELDKNL 180
                          E+EL A L  +E+E   KN+
Sbjct: 1082 --------------EEELQAALARVEEEAAQKNM 1101



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 33/165 (20%), Positives = 71/165 (43%), Gaps = 27/165 (16%)

Query: 23   QEAIQRLRDTEEMLS---KKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQL 79
            +E ++  +   E+++   KK      +I  +L   + H  KN+ A  Q  ++ K  + +L
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794

Query: 80   AQIDGT--------LSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMD--IDKVD 129
             +++GT        ++ +E +   LE    N    K    A K ++     +   + +VD
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNE--TKERQAACKQVRRTEKKLKDVLLQVD 1852

Query: 130  ELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQE 174
            +  ++    ++ A++ ST +             +L  +LEE E+E
Sbjct: 1853 DERRNAEQYKDQADKASTRLK------------QLKRQLEEAEEE 1885



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 42/166 (25%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 24   EAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQAL----KRKKRYEKQL 79
            +A++ L +  E   + +  LEK  +Q L   +       +  LQ       ++K+ E QL
Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKA-KQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254

Query: 80   AQIDGTLSTIEFQREALENANTNTEV-LKNM-GYAAKA-MKAAHDNMDIDKVDELMQDIA 136
             ++    +  E  R  L +  T  +V L N+ G  +++  K++    D   ++  +QD  
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT- 1313

Query: 137  DQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLE 182
             Q+ L EE    +S      +   EDE  +  E+LE+EE  K+ LE
Sbjct: 1314 -QELLQEENRQKLSLSTKLKQV--EDEKNSFREQLEEEEEAKHNLE 1356


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/142 (23%), Positives = 69/142 (48%), Gaps = 14/142 (9%)

Query: 45  KKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLS----TIEFQREALENAN 100
           KK+++E    KKH  K+K    +  K++   EK+  +   +      ++EF RE  +   
Sbjct: 618 KKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENF 677

Query: 101 TNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFD 160
             ++  +++      +   H+++ ++K  +L ++I D +   E+    +SK   F EE  
Sbjct: 678 FKSDETEDL-----FLNMEHESLTLEKKSKLEKNIKDDKSTKEK---HVSKERNFKEE-- 727

Query: 161 EDELMAELEELEQEELDKNLLE 182
            D++  E E+  +EE  K+L E
Sbjct: 728 RDKIKKESEKSFREEKIKDLKE 749



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 17/153 (11%)

Query: 33  EEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQ 92
           E +  +K+  LEK I+ + +  +KH +K +    +  K KK  EK   +       I+  
Sbjct: 693 ESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFRE-----EKIKDL 747

Query: 93  REALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELM------QDIADQQELAEEIS 146
           +E  EN  T+    K+  + +  M A  +++ +  V++ +      + I + +E  E+ S
Sbjct: 748 KEERENIPTD----KDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRS 803

Query: 147 TAISKPVGFGEE--FDEDELMAELEELEQEELD 177
               K +   E   F++++ +    + E+++LD
Sbjct: 804 QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLD 836


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 34/142 (23%), Positives = 69/142 (48%), Gaps = 14/142 (9%)

Query: 45  KKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLS----TIEFQREALENAN 100
           KK+++E    KKH  K+K    +  K++   EK+  +   +      ++EF RE  +   
Sbjct: 641 KKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENF 700

Query: 101 TNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFD 160
             ++  +++      +   H+++ ++K  +L ++I D +   E+    +SK   F EE  
Sbjct: 701 FKSDETEDL-----FLNMEHESLTLEKKSKLEKNIKDDKSTKEK---HVSKERNFKEE-- 750

Query: 161 EDELMAELEELEQEELDKNLLE 182
            D++  E E+  +EE  K+L E
Sbjct: 751 RDKIKKESEKSFREEKIKDLKE 772



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 17/153 (11%)

Query: 33  EEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQ 92
           E +  +K+  LEK I+ + +  +KH +K +    +  K KK  EK   +       I+  
Sbjct: 716 ESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFRE-----EKIKDL 770

Query: 93  REALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELM------QDIADQQELAEEIS 146
           +E  EN  T+    K+  + +  M A  +++ +  V++ +      + I + +E  E+ S
Sbjct: 771 KEERENIPTD----KDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRS 826

Query: 147 TAISKPVGFGEE--FDEDELMAELEELEQEELD 177
               K +   E   F++++ +    + E+++LD
Sbjct: 827 QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLD 859


>gi|203096856 kinesin family member 7 [Homo sapiens]
          Length = 1343

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 39/173 (22%), Positives = 83/173 (47%), Gaps = 23/173 (13%)

Query: 28   RLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLS 87
            R+++ E    ++Q+ L+ K E E+ A ++        ++ +L+++++ E+Q   +D  + 
Sbjct: 862  RVKELELKHEQQQKILKIKTE-EIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEME 920

Query: 88   TIEFQREALEN------------ANTNTEVLKNMGYAAKAMKAAHD-NMDIDKVDELMQD 134
             +  QR ALE             A     + +  G  +K ++++   N DI +V   ++ 
Sbjct: 921  KVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEH 980

Query: 135  IADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEE--LDKNLLEISG 185
            +  ++EL+E+     S  +  G    + ++  E++ L QE+  L K  LEI G
Sbjct: 981  L--EKELSEK-----SGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDG 1026


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 32/170 (18%), Positives = 73/170 (42%), Gaps = 15/170 (8%)

Query: 23  QEAIQRLRDTEEMLSKKQEFLEKKIE---QELTAAKKHGTKNKRAALQALKRKKRYEKQL 79
           +E IQ  ++   +L+ ++E L+++++   QEL   K      K   +  L+  K   +QL
Sbjct: 299 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQL 358

Query: 80  AQIDGTL---------STIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDE 130
            Q  G +          T+E + E +    +  + +   G   +  K   +    +++++
Sbjct: 359 EQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEK 418

Query: 131 LMQDIADQQELAEEISTAISKPVGFGEEFDEDE---LMAELEELEQEELD 177
            +      +E   ++   + + +   E+  E+E   L  EL  ++QE +D
Sbjct: 419 ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVD 468



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 25/171 (14%)

Query: 29  LRDTEEMLSKKQEFLE------KKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82
           L++ ++ L + Q  +E      K+ E EL  A       +       ++ K YE+QLAQ+
Sbjct: 765 LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQL 824

Query: 83  DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDK--VDELMQDIADQQE 140
              L  +E +R  L       E  K         K     +D  K  V +LMQ +  Q  
Sbjct: 825 QQKLLDLETERILLTKQVAEVEAQK---------KDVCTELDAHKIQVQDLMQQLEKQNS 875

Query: 141 LAEEISTAISKPV------GFGEEFDEDELMAELEE--LEQEELDKNLLEI 183
             E+   ++++        G  E+    +++ E E   L+  E  K  +EI
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEI 926


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 19/200 (9%)

Query: 24  EAIQRLRDTEEMLSKKQEFLEKKI-EQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82
           E  +++RD E+ +  ++E +EKK  EQE     +     +   ++  ++K R E+++ + 
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR- 606

Query: 83  DGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM--DIDKVDELMQDIADQQE 140
                  E + +  E      E  + M    + M+   + M    +K+ E  + + +QQ 
Sbjct: 607 -------EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659

Query: 141 LAEEISTAISKPVGFGEEFDEDELMAELEE--LEQEELDKNLLEISGPETVPLPNVPSIA 198
           L E+      + +   E+  E E M E EE   EQE+++K   E    +T     +    
Sbjct: 660 LPEQ-----KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE-QEKKTWDQEKMREEE 713

Query: 199 LPSKPAKKKEEEDDDMKELE 218
              +  KK  EE++ M+E E
Sbjct: 714 SMREREKKMREEEEMMREQE 733



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 9/158 (5%)

Query: 23  QEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQI 82
           +E  +++R+ EEM+ +++E ++++ E+     +K   + ++   Q  K  ++ EK   Q 
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651

Query: 83  DGTLST--IEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQE 140
           +       +  Q+E L       E  K      K  +   + M+  K  E  +   DQ++
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE--QEKME-KKTQEQEKKTWDQEK 708

Query: 141 LAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDK 178
           + EE S    +     +  +E+E+M E EE  QE+ +K
Sbjct: 709 MREEESMREREK----KMREEEEMMREQEEKMQEQEEK 742



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 40/212 (18%), Positives = 94/212 (44%), Gaps = 20/212 (9%)

Query: 24  EAIQRLRDTEEMLSKKQ---EFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLA 80
           E  +RLR+ EE + +++   E +EK  E++    ++  T+++   +Q  +R +  EK++ 
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460

Query: 81  QIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM--------DIDKVDELM 132
           + +    T+  Q E ++    N    +   +  + +    + +          +K+ E  
Sbjct: 461 EEE---ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517

Query: 133 QDIADQQEL-AEEISTAISKPVGFGEE--FDEDELMAELEEL---EQEELDKNLLEISGP 186
           + I DQ+E+  +E      + +   E+  ++++E M + E+    ++E ++K   E    
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577

Query: 187 ETVPLPNVPSIALPSKPAKKKEEEDDDMKELE 218
                  +       +  KK  EE++ M+E E
Sbjct: 578 TWDQEEKMREEERMREREKKMREEEEMMREQE 609


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 47/205 (22%), Positives = 84/205 (40%), Gaps = 17/205 (8%)

Query: 24   EAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQID 83
            E  QRL    E L  +   L+KK+E E+   ++  T  +   +Q L  K++ +    + +
Sbjct: 832  ETKQRLSSQIEKLEHEISHLKKKLENEV---EQRHTLTRNLDVQLLDTKRQLD---TETN 885

Query: 84   GTLSTIEFQREALENANTNTEVLKNMGY---------AAKAMKAAHDNMDIDKVDELMQD 134
              L+T E  + A +   T  + L NM             K   +  +++D D V +L Q 
Sbjct: 886  LHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVD-DLVSQLRQT 944

Query: 135  IADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNV 194
                 +L E + T+ S    +       E     E+   EE+ KN +E+   E+      
Sbjct: 945  EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKN-IEVRLKESAEFQTQ 1003

Query: 195  PSIALPSKPAKKKEEEDDDMKELEN 219
                L     +K+E +DD  + +E+
Sbjct: 1004 LEKKLMEVEKEKQELQDDKRRAIES 1028



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 28/131 (21%), Positives = 64/131 (48%), Gaps = 9/131 (6%)

Query: 63  RAALQALKRK-KRYEKQLAQIDGTLSTI--EFQREALENANTNTEVLKNMGYAAKAMKAA 119
           +AAL+ L+   + Y+K+ A+ +   +    + Q +  +  + NT++   + +A+K  +  
Sbjct: 669 KAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEML 728

Query: 120 HDNM-----DIDKVDELMQDIADQQELAEEISTAISKPV-GFGEEFDEDELMAELEELEQ 173
            DN+     +I  + E  Q +    +  E+I   +++ + G  E+    E+ AE  + E+
Sbjct: 729 QDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEK 788

Query: 174 EELDKNLLEIS 184
           E L  + + +S
Sbjct: 789 EMLKLSEVRLS 799


>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
           [Homo sapiens]
          Length = 766

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 47/214 (21%), Positives = 95/214 (44%), Gaps = 35/214 (16%)

Query: 20  PTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNK---------RAALQALK 70
           P  +E I  LR+ EE  S ++     ++ Q+   A    TK+          RA  Q LK
Sbjct: 411 PVAEEEIL-LREFEERQSLRKR---SELNQDAEPASSQETKDSSSQEVLSELRALSQKLK 466

Query: 71  RKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDE 130
            K +  KQ A  +GT+  ++ +  A E A                ++ +     +++++E
Sbjct: 467 EKHQSRKQKASSEGTVPQVQREEPAPEEAEP------------LLLQRSERVQTLEELEE 514

Query: 131 LMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVP 190
           L ++   Q +        + +PV  G++ +           E++E ++ L+ +    T  
Sbjct: 515 LGKEDCFQNK-------ELPRPVLEGQQSERTPNNRPDAPKEKKEKEQ-LINLQNFLTTQ 566

Query: 191 LPNVPSIALPSKPAKKKEEEDDDMKEL--ENWAG 222
            P+V S+A+P+   + ++EE+ D +++  E +AG
Sbjct: 567 SPSVRSLAVPTIIEELEDEEERDQRQMIKEAFAG 600


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.127    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,769,430
Number of Sequences: 37866
Number of extensions: 418235
Number of successful extensions: 3077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 367
Number of HSP's that attempted gapping in prelim test: 2570
Number of HSP's gapped (non-prelim): 837
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.