Guide to the Human Genome
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Search of human proteins with 27883882

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27883882 P18SRP protein [Homo sapiens]
         (155 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27883882 P18SRP protein [Homo sapiens]                             312   6e-86
gi|168229156 NFKB activating protein [Homo sapiens]                    67   5e-12
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              67   5e-12
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]            65   2e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    64   4e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            64   5e-11
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            61   3e-10
gi|56090620 NFKB activating protein-like [Homo sapiens]                61   3e-10
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            61   4e-10
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    60   8e-10
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    60   8e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    59   1e-09
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    59   1e-09
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                58   4e-09
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          58   4e-09
gi|21361576 zinc finger, CCHC domain containing 17 [Homo sapiens]      57   8e-09
gi|151301228 formin binding protein 3 [Homo sapiens]                   56   1e-08
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  55   2e-08
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    54   4e-08
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    54   4e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    54   4e-08
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    54   4e-08
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    53   9e-08
gi|42718020 retinitis pigmentosa 9 [Homo sapiens]                      53   9e-08
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     52   2e-07
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [...    52   2e-07
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H...    52   2e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           52   2e-07
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           52   2e-07
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           52   2e-07

>gi|27883882 P18SRP protein [Homo sapiens]
          Length = 155

 Score =  312 bits (800), Expect = 6e-86
 Identities = 155/155 (100%), Positives = 155/155 (100%)

Query: 1   MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELN 60
           MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELN
Sbjct: 1   MAVPGCNKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELN 60

Query: 61  KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKE 120
           KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKE
Sbjct: 61  KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKE 120

Query: 121 KKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           KKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK
Sbjct: 121 KKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 67.4 bits (163), Expect = 5e-12
 Identities = 38/107 (35%), Positives = 59/107 (55%), Gaps = 7/107 (6%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           S+TS+  S+EE ++       +  R  E  +K+++K   K K KK  + S S S +E D+
Sbjct: 171 STTSASTSEEEKKK-------KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           S +  ++  KK KKKEKK K +  K+ KK  KK +KE   S+   S+
Sbjct: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQ 270



 Score = 50.4 bits (119), Expect = 6e-07
 Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 20/113 (17%)

Query: 51  DSDE----ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
           DSDE    E+EE  K           EEEKKK+ S+ K + KK+RK+          +SK
Sbjct: 156 DSDEHTPVEDEEPKKSTTSAS---TSEEEKKKKSSRSKERSKKRRKKK---------SSK 203

Query: 107 QKKQKYQK---KEKKKEKKSKSKKGKHH-KKEKKKRKKEKHSSTPNSSEFSRK 155
           +K +KY +    +   E  S  +  K   KK KKK KK+KH S     + S+K
Sbjct: 204 RKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKK 256



 Score = 43.9 bits (102), Expect = 6e-05
 Identities = 23/79 (29%), Positives = 43/79 (54%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           S  S  DSD E +  ++    + K+  ++E+KKK +SK+  K + K+ R  SS S+ +++
Sbjct: 210 SEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKES 269

Query: 105 SKQKKQKYQKKEKKKEKKS 123
            ++  +   K   K E+ S
Sbjct: 270 QEEFLENPWKDRTKAEEPS 288


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 67.4 bits (163), Expect = 5e-12
 Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 33/133 (24%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRI--------------NEEEEKKKEKSKEKIK---- 86
           SS+SS DS++E ++  K +  ++ R               ++E  KKK+KSK++ +    
Sbjct: 113 SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKD 172

Query: 87  ---LKKKRKRSY-----------SSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK 132
              L KKRK+SY           S S  EED   +KK++ +++E+ KEK  K KK K HK
Sbjct: 173 VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKK-KQHK 231

Query: 133 KEKKKRKKEKHSS 145
           K  KK+KK+  SS
Sbjct: 232 KHSKKKKKKSGSS 244



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 41/111 (36%), Positives = 57/111 (51%), Gaps = 23/111 (20%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSS--STEE 102
           SS+SS DS   + +            +E+EEKK+ K +     KKK+ RSY SS  ST E
Sbjct: 106 SSSSSSDSSSSSSD------------SEDEEKKQGKRR-----KKKKNRSYKSSQSSTHE 148

Query: 103 DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
             S+ K    +  +KKK+ K +++K K  +   KKRKK      P SSE S
Sbjct: 149 SESESK----ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESS 195



 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 36/126 (28%), Positives = 66/126 (52%), Gaps = 16/126 (12%)

Query: 45  SSTSSEDSDEENEELNK-LQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE- 102
           S   +E  ++ NE   K L+  +EK ++  E   K++ ++K K KKK  RS SSSS+ + 
Sbjct: 55  SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK-KRKKKSCRSSSSSSSSDS 113

Query: 103 -----DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKE--------KKKRKKEKHSSTPNS 149
                D+  ++K++ ++++KKK +  KS +   H+ E        KKK+ K++     + 
Sbjct: 114 SSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDV 173

Query: 150 SEFSRK 155
              S+K
Sbjct: 174 RSLSKK 179



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 36/122 (29%), Positives = 62/122 (50%), Gaps = 24/122 (19%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKI-----------KLKKKRKR--------- 93
           E  +  +K  A  E+++NE  +K+ EKS+EK+           + KKKRK+         
Sbjct: 49  ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSS 108

Query: 94  -SYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKE---KKKRKKEKHSSTPNS 149
            S  SSS+  D+  ++K++ ++++KKK +  KS +   H+ E   K+  KK+K S     
Sbjct: 109 SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168

Query: 150 SE 151
            E
Sbjct: 169 KE 170



 Score = 37.4 bits (85), Expect = 0.005
 Identities = 20/70 (28%), Positives = 41/70 (58%)

Query: 84  KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKH 143
           K +L+ K+  S + +  EE  ++  K++ +K  +K    ++S   K  +K+K+K+K  + 
Sbjct: 45  KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104

Query: 144 SSTPNSSEFS 153
           SS+ +SS+ S
Sbjct: 105 SSSSSSSDSS 114



 Score = 34.3 bits (77), Expect = 0.044
 Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 44  VSSTSSEDSD-EENEELNKLQALQEK-RINEEEEKKKEKSKEKIKLKKKRKRSYSSSS 99
           +SS SS +SD EE+ +  K +  +E+ +  E+ +KKK+K  +K   KKK+K   S  S
Sbjct: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 83  EKIKLKKKRKRSYSSSSTE-EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKE 141
           E++K + + K++ S +  E E+   +  +K  +K ++K         K  +++KK++KK 
Sbjct: 42  EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101

Query: 142 KHSSTPNSSEFS 153
             SS+ +SS  S
Sbjct: 102 CRSSSSSSSSDS 113



 Score = 30.0 bits (66), Expect = 0.83
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 32/117 (27%)

Query: 68  KRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQK-YQKKEKKKEKKSKSK 126
           + + ++ E KK  SK   + ++K   ++     E + S++K     +   KK+E+K K K
Sbjct: 42  EEVKKQLENKKTGSKALAEFEEKMNENWKK---ELEKSREKLLSGNESSSKKRERKKKRK 98

Query: 127 K----------------------------GKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           K                            GK  KK+K +  K   SST  S   S++
Sbjct: 99  KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155


>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 65.1 bits (157), Expect = 2e-11
 Identities = 34/70 (48%), Positives = 47/70 (67%), Gaps = 11/70 (15%)

Query: 73  EEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK 132
           + E+KKEK KEK K KKK+K+            K+KK+K +KK+KKK+KK + +K K  +
Sbjct: 101 QREEKKEKEKEKKKKKKKKKK-----------KKKKKKKKKKKKKKKKKKKRKRKRKRKR 149

Query: 133 KEKKKRKKEK 142
           K KKKRKK+K
Sbjct: 150 KRKKKRKKKK 159



 Score = 60.5 bits (145), Expect = 6e-10
 Identities = 34/83 (40%), Positives = 52/83 (62%), Gaps = 13/83 (15%)

Query: 59  LNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKK 118
           L+ L   +EK+  E+E+KKK+K K+K K KKK+K             K+KK+K +KK++K
Sbjct: 96  LHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKK-------------KKKKKKKKKKKRK 142

Query: 119 KEKKSKSKKGKHHKKEKKKRKKE 141
           +++K K K+ K  KK+KKK   E
Sbjct: 143 RKRKRKRKRKKKRKKKKKKTGNE 165



 Score = 50.1 bits (118), Expect = 8e-07
 Identities = 27/79 (34%), Positives = 50/79 (63%), Gaps = 11/79 (13%)

Query: 53  DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112
           +E+ E+  + +  ++K+  ++++KKK+K K+K K KKKRKR            +++K+K 
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKR-----------KRKRKRKR 151

Query: 113 QKKEKKKEKKSKSKKGKHH 131
           +KK KKK+KK+ ++  K H
Sbjct: 152 KKKRKKKKKKTGNEGAKIH 170



 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 22/55 (40%), Positives = 36/55 (65%)

Query: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           E++  K+KK+K +KK+KKK+KK K KK K  KK++K+++K K        +  +K
Sbjct: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 11/79 (13%)

Query: 55  ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQK 114
           + EE  + +  ++K+  ++++KKK+K K+K K KKK+K+            +++K+K ++
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKK-----------KRKRKRKRKR 149

Query: 115 KEKKKEKKSKSKKGKHHKK 133
           K KKK KK K K G    K
Sbjct: 150 KRKKKRKKKKKKTGNEGAK 168



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 23/50 (46%), Positives = 34/50 (68%)

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           ++KK+K ++K+KKK+KK K KK K  KK+KKK+KK+K        +  RK
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 22/54 (40%), Positives = 36/54 (66%)

Query: 102 EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           E+  +++K+K +KK+KKK+KK K KK K  KK+KKK+K+++        +  RK
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 25/56 (44%), Positives = 36/56 (64%), Gaps = 1/56 (1%)

Query: 101 EEDTSKQK-KQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           EE   K+K K+K +KK+KKK+KK K KK K  KK+KKKRK+++        +  +K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158



 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 23/46 (50%), Positives = 30/46 (65%)

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           Q+ +KKEK+KEKK K KK K  KK+KKK+KK+K        +  RK
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146



 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 22/50 (44%), Positives = 34/50 (68%)

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +++++K ++KEKKK+KK K KK K  KK+KKK+KK+K        +  RK
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 64.3 bits (155), Expect = 4e-11
 Identities = 34/104 (32%), Positives = 65/104 (62%), Gaps = 10/104 (9%)

Query: 49  SEDSDEENEELNKLQALQEKRINEEEEKKK----EKSKEKIKLKKKRKRSYSSSSTEEDT 104
           +E+++EE E+  K +  ++++  E+E+KKK    EK KEK + +KKRKR       EE+ 
Sbjct: 16  TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75

Query: 105 SKQK------KQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
            +++      K++ +K+E ++ KK K ++ K  ++EKKK+++ K
Sbjct: 76  EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119



 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 34/109 (31%), Positives = 64/109 (58%), Gaps = 9/109 (8%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
           +E EE  + +  +E+   E+E K+KEK KEK K K+K+K++  +   +E   ++KK+K +
Sbjct: 8   KETEETEETEETEEEE--EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 114 KKEKKKEKK-------SKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K+KK+E++        + +K +  K+E ++RKK+K        E  +K
Sbjct: 66  RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 31/88 (35%), Positives = 52/88 (59%), Gaps = 3/88 (3%)

Query: 55  ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQK 114
           + +E  K     EKR  +EEE+KK K K K   KKK +        EE+  K++++K + 
Sbjct: 38  KEKEKKKKTKETEKRKEKEEEEKKRKRKRK---KKKEEEEREEEEEEEEEEKEEEEKEEG 94

Query: 115 KEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
           + +KK+KK + K+ +  KK+K++RK +K
Sbjct: 95  RRRKKKKKRRRKEEEEEKKKKRRRKTKK 122



 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 32/107 (29%), Positives = 63/107 (58%), Gaps = 18/107 (16%)

Query: 54  EENEELNKLQALQEKRINEEEEKK----KEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           ++ ++  + +  +E    EEEE+K    KEK KEK K K+K+K++  +   +E   ++KK
Sbjct: 2   KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61

Query: 110 QKYQKKEKKKE--------------KKSKSKKGKHHKKEKKKRKKEK 142
           +K ++K+KK+E              ++ + ++G+  KK+KK+R+KE+
Sbjct: 62  RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 9/79 (11%)

Query: 82  KEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSK---------KGKHHK 132
           K+K K KK+ + +  +  TEE+  K+ K+K ++KEK+KEK+ K K         K +  K
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 133 KEKKKRKKEKHSSTPNSSE 151
           K K+KRKK+K        E
Sbjct: 61  KRKRKRKKKKEEEEREEEE 79



 Score = 43.9 bits (102), Expect = 6e-05
 Identities = 28/91 (30%), Positives = 49/91 (53%), Gaps = 16/91 (17%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
           T      EE E+  K +  ++K   E EE+++E+ +EK + +K           EE   +
Sbjct: 49  TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK-----------EEGRRR 97

Query: 107 QKKQKYQKKEKKKEKKSKSKKGKHHKKEKKK 137
           +KK+K ++KE+++EKK K +     +K KKK
Sbjct: 98  KKKKKRRRKEEEEEKKKKRR-----RKTKKK 123



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 20/91 (21%), Positives = 52/91 (57%), Gaps = 10/91 (10%)

Query: 37  KRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYS 96
           K+    +      ++ +E+  +  + +  +E+   EEEE+++E+ +E+ K + +R++   
Sbjct: 42  KKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK-- 99

Query: 97  SSSTEEDTSKQKKQKYQKKEKKKEKKSKSKK 127
                    K++++K +++EKKK+++ K+KK
Sbjct: 100 --------KKKRRRKEEEEEKKKKRRRKTKK 122



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 8/68 (11%)

Query: 88  KKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTP 147
           KKK+K+   +  TEE    ++ ++ ++KE K+++K K K     +KEK+K+KK K +   
Sbjct: 1   KKKKKKKKETEETEET---EETEEEEEKEGKRKEKRKEK-----RKEKEKKKKTKETEKR 52

Query: 148 NSSEFSRK 155
              E   K
Sbjct: 53  KEKEEEEK 60


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 63.9 bits (154), Expect = 5e-11
 Identities = 30/116 (25%), Positives = 66/116 (56%), Gaps = 1/116 (0%)

Query: 41  VLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSST 100
           ++  S  S   +  E+E   + +  ++++   E+E+K+E+ K++ K +KKR+R       
Sbjct: 19  MVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK 78

Query: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHH-KKEKKKRKKEKHSSTPNSSEFSRK 155
            ++  KQ+K++ +K+ +K++K+ K ++ K   ++E+KK+K+ K     N     RK
Sbjct: 79  RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 28/106 (26%), Positives = 63/106 (59%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E   +E E+  K +  +E+R  ++E+KK+E+ +   + +KK+K         +   ++K+
Sbjct: 76  ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K +KK+++KE+K + ++GK  +K KK++K+E+      + +  +K
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 30/95 (31%), Positives = 54/95 (56%), Gaps = 3/95 (3%)

Query: 57  EELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKE 116
           E   K +  + +R N++  ++K K + K K +K+RKR       E    K+KK+K +++E
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER---KRKKRKKEERE 169

Query: 117 KKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           KK+E+  K +K +  +KE+++RKKE+        E
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKE 204



 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 31/104 (29%), Positives = 58/104 (55%), Gaps = 1/104 (0%)

Query: 53  DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTE-EDTSKQKKQK 111
           + E +   + +  +E+R  E  ++KKEK K + K + +R+R       E E  +KQ++++
Sbjct: 74  ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133

Query: 112 YQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
            +KK +KK+++ + K+ K   K ++KRKK K        E +RK
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177



 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 25/101 (24%), Positives = 62/101 (61%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
           +E E  NK +  ++++   +++++KE+ +EK + K++RKR        E   ++ +++ +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
           K+ ++KE++ + K+ K  +++KK+RKK++ +     S+  R
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221



 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 25/102 (24%), Positives = 60/102 (58%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
           E  +E  + +  +EK+  E  EK++ K K++ K +++++R       +++  +++++  Q
Sbjct: 70  ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           ++E+K++K+ K K+ K  K+EK++ K+E+        E  +K
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171



 Score = 57.0 bits (136), Expect = 6e-09
 Identities = 22/97 (22%), Positives = 58/97 (59%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           ++ + EN++  + +  + ++    +E+K+EK + K + K+K+++        E   K++K
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSST 146
           ++ ++KE+++ KK + K+ +  K+ KK RK ++ + +
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217



 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 27/110 (24%), Positives = 60/110 (54%), Gaps = 4/110 (3%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKI----KLKKKRKRSYSSSSTEEDTS 105
           ++   E  +  K +  + +R  E E K+KE+ K++     K ++KRK+       ++   
Sbjct: 52  KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +++K+K ++KE+++E K + ++ +  +++KK+RK+ K        E  RK
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161



 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 20/103 (19%), Positives = 57/103 (55%)

Query: 53  DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112
           +++  E  +    + K+  E +E+++E  + + + +KKR++       + +  + K+++ 
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERK 159

Query: 113 QKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +KK KK+E++ K ++ +  +K++++RK+ +        E  +K
Sbjct: 160 RKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202



 Score = 50.4 bits (119), Expect = 6e-07
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 1/105 (0%)

Query: 51  DSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQ 110
           ++ +  E   K +  +++R   + EK++ K + K K +KK +R        ++  K++++
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185

Query: 111 KYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTP-NSSEFSR 154
           K +++ KK+ KK + KK +  K  K  R+ +     P   S F+R
Sbjct: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230



 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 20/102 (19%), Positives = 60/102 (58%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
           +E ++  + Q  + +R  ++E K++E+  ++ + +K++KR       E    K++ ++ +
Sbjct: 99  KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           K++K+K+++ + K+ ++ K+ KK+R++++        +  R+
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200



 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 11/105 (10%)

Query: 44  VSSTSSEDSDEENEELNKLQA--LQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTE 101
           V + SS  + + N EL  +    + +     E E+KKE+ +     ++KRKR        
Sbjct: 2   VKAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERRE-----REKRKREREKERKR 56

Query: 102 EDTSKQKKQKYQK---KEKKKEKKSKSKKGKHHK-KEKKKRKKEK 142
           E   K+KK++ ++   KE+++++K + K+ K  + KE++KRKKEK
Sbjct: 57  ERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101



 Score = 35.0 bits (79), Expect = 0.026
 Identities = 15/61 (24%), Positives = 33/61 (54%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           ++  E+  E N+ +  +E+   E  E+KKE+ KE+ K K+++K   +   T+    +  +
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLR 224

Query: 110 Q 110
           +
Sbjct: 225 E 225


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 30/97 (30%), Positives = 60/97 (61%), Gaps = 1/97 (1%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
           TS E  + E +E  K +  +E+   +EE +K+ + KE+ K ++K+         E++  +
Sbjct: 126 TSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185

Query: 107 QKKQKYQKKEKKKEKKSKSKK-GKHHKKEKKKRKKEK 142
           +KK++  +KE+KKE++ K ++  K  +K+K++RKKE+
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEERKKER 222



 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 28/106 (26%), Positives = 58/106 (54%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E   EE E   + +  + K   E+E++KK++ KE+ +  K+ K        + +  K+++
Sbjct: 89  ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K +++EK++E+K + K+ +    EK++ +KEK        E +RK
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194



 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 35/118 (29%), Positives = 60/118 (50%), Gaps = 9/118 (7%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEK------KKEKSKEKIKLKKKRKRSYSSSST 100
           T  E   E   E  K +  +EKR  E E++      KKEK  E+ K +++RK+       
Sbjct: 47  TRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106

Query: 101 EEDTSKQKKQKYQKKEK---KKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +E   K+K++K +KKE+    KE K + +K +  ++E+K+R+++K           RK
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164



 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 10/116 (8%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKK----------EKSKEKIKLKKKRKRSYSSSS 99
           E   E   E  K +   E++  E E KK+          EK K K K KK+R R+     
Sbjct: 72  EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK 131

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
             E   ++K+++ +++E+KKE++ K ++ K  KK ++K+  EK           RK
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 29/102 (28%), Positives = 63/102 (61%), Gaps = 5/102 (4%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
           E   E+   +  +++R +E +++++E+ K K + +K+RKR       +E   ++KK++ +
Sbjct: 40  EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK---KEKKGERKKEERE 96

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K++++EK  ++K+G+  +K KKK KKE+  ++    E  RK
Sbjct: 97  RKKRRREK--ENKEGEEKEKRKKKEKKERGRTSKEGKERERK 136



 Score = 55.8 bits (133), Expect = 1e-08
 Identities = 26/95 (27%), Positives = 60/95 (63%), Gaps = 4/95 (4%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKS----KEKIKLKKKRKRSYSSSSTEEDTS 105
           ++  E+  E  + +  + K++ E+EE++KEK     K++ + +K+RK+        E   
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKK 140
           ++KK++ +KKE++K++++  ++ +  K+E+K+RKK
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 17/119 (14%)

Query: 50  EDSDEENEELNKLQALQEK------RINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEED 103
           E  ++E EE  K +  ++K      +  +E E+K+E+ +E+ K ++++K         ++
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162

Query: 104 TSK-----------QKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
             K           ++K+K +K+ KK+E+  K +K +  +KE+++RKKE+        E
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE 221



 Score = 53.1 bits (126), Expect = 9e-08
 Identities = 28/109 (25%), Positives = 62/109 (56%), Gaps = 10/109 (9%)

Query: 54  EENEELNKLQALQEKRINEE-------EEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
           EE E+  K +  +  R ++E       EE+K+E+ KE+ + K++R++       +E   +
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE---RERKERKKR 166

Query: 107 QKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           ++KQ  +K+E++KEK+ K +K +   ++++K+++E+        E  +K
Sbjct: 167 ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215



 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 24/105 (22%), Positives = 58/105 (55%)

Query: 51  DSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQ 110
           ++ +E ++  + +  +E+R  E+ ++++EK +++ + KK++K        E    +++K+
Sbjct: 46  ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105

Query: 111 KYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
             + +EK+K KK + K+     KE K+R++++        E  RK
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150



 Score = 50.4 bits (119), Expect = 6e-07
 Identities = 25/80 (31%), Positives = 50/80 (62%), Gaps = 3/80 (3%)

Query: 78  KEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK--KEK 135
           +E+ +E I+ +K+ K+   S   +E   ++K+++ ++KE+K+E+  K KKG+  K  +E+
Sbjct: 39  RERERE-IETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97

Query: 136 KKRKKEKHSSTPNSSEFSRK 155
           KKR++EK +      E  +K
Sbjct: 98  KKRRREKENKEGEEKEKRKK 117



 Score = 32.3 bits (72), Expect = 0.17
 Identities = 14/42 (33%), Positives = 31/42 (73%), Gaps = 1/42 (2%)

Query: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
           + +  +++++   +KE KKE++S+ KK +  ++EK+KR++EK
Sbjct: 35  QSEIREREREIETRKEGKKERESERKK-ERREREKRKREREK 75


>gi|56090620 NFKB activating protein-like [Homo sapiens]
          Length = 402

 Score = 61.2 bits (147), Expect = 3e-10
 Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 10/111 (9%)

Query: 51  DSDE----ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK------RSYSSSST 100
           DSDE    E+EE    Q       N EE +KK+ S+ + K K+K K      R YS S +
Sbjct: 147 DSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDS 206

Query: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
             ++         KK  K +KK K KK K  KK+ KK KKE   S+   SE
Sbjct: 207 NSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSE 257



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)

Query: 61  KLQALQEKRINEEEEKKKEK-----SKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKK 115
           +L + +   + +EEE   +K     S  +   KKK  RS +    +  +SK+K +KY   
Sbjct: 145 QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDS 204

Query: 116 --------------EKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
                         +KK+ K  K KK K HK +KKK KK K  S+ +S + S +
Sbjct: 205 DSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258



 Score = 38.1 bits (87), Expect = 0.003
 Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 10/67 (14%)

Query: 43  DVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSS--- 99
           D  S S  D++ ++++        +KR+  +++KKK+K K K K  KK K+  S SS   
Sbjct: 203 DSDSNSESDTNSDSDD-------DKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKD 255

Query: 100 TEEDTSK 106
           +EED S+
Sbjct: 256 SEEDLSE 262


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 60.8 bits (146), Expect = 4e-10
 Identities = 28/77 (36%), Positives = 53/77 (68%)

Query: 66  QEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKS 125
           ++K+    ++KKK  +K+K   K K++ + +  +T   T +++K+K ++KEK+KEK+ + 
Sbjct: 35  KKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEK 94

Query: 126 KKGKHHKKEKKKRKKEK 142
           +K K  KK+KKK+KK+K
Sbjct: 95  EKEKKKKKKKKKKKKKK 111



 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 29/82 (35%), Positives = 53/82 (64%)

Query: 61  KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKE 120
           K +  ++K+  +   KKK+K+  K K   K K+  +++     T+ ++K+K ++KEK+KE
Sbjct: 28  KKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKE 87

Query: 121 KKSKSKKGKHHKKEKKKRKKEK 142
           K+ + +K K  KK+KKK+KK+K
Sbjct: 88  KEKEKEKEKEKKKKKKKKKKKK 109



 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 27/90 (30%), Positives = 50/90 (55%)

Query: 66  QEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKS 125
           ++K+  ++++KKK   K+K K   K+K +  +      T K      ++KEK+KEK+ + 
Sbjct: 27  RKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEK 86

Query: 126 KKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K K  +KEK+K+KK+K        + + K
Sbjct: 87  EKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 30/111 (27%)

Query: 57  EELNKLQALQEKRINEEEE------------KKKEKSKEKIKLKKK-----------RKR 93
           +EL+K  A+++  +  E+E            KKK+K K  +K KKK           +KR
Sbjct: 2   QELDKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKR 61

Query: 94  SYSSSSTEEDTSKQK-------KQKYQKKEKKKEKKSKSKKGKHHKKEKKK 137
           + ++  T   T+K+K       K+K ++KEK+KEK+ K KK K  KK+KKK
Sbjct: 62  TTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112



 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 25/102 (24%), Positives = 55/102 (53%), Gaps = 5/102 (4%)

Query: 59  LNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEK- 117
           + K+  + EK    +  +KK+ +K+K K K   K+   +++ ++ T+K KK+    K+  
Sbjct: 10  MEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTT 69

Query: 118 ----KKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
               K+++K K K+ +  K+++K+++KEK        +  +K
Sbjct: 70  TTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKK 111



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 20/81 (24%), Positives = 41/81 (50%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
           T+ +   ++     K +   +K+   + +K+   +K+      K K        E++  K
Sbjct: 31  TTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEK 90

Query: 107 QKKQKYQKKEKKKEKKSKSKK 127
           +K+++ +KK+KKK+KK K KK
Sbjct: 91  EKEKEKEKKKKKKKKKKKKKK 111



 Score = 37.4 bits (85), Expect = 0.005
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 5/61 (8%)

Query: 37  KRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYS 96
           KR      ++T++    E+ +E  K     EK   +E+EK+KEK K+K K KKK+K+  +
Sbjct: 60  KRTTTTKKTTTTTTKEKEKEKEKEK-----EKEKEKEKEKEKEKKKKKKKKKKKKKKKLN 114

Query: 97  S 97
           +
Sbjct: 115 A 115



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 15/48 (31%), Positives = 32/48 (66%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK 92
           ++T++++ ++E E+  + +  +EK   +E++KKK+K K+K K K   K
Sbjct: 69  TTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116



 Score = 26.6 bits (57), Expect = 9.2
 Identities = 13/51 (25%), Positives = 30/51 (58%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSST 100
           ++ ++E E+  + +  +EK+  ++++KKK+K K   K+      S+S  +T
Sbjct: 80  KEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKVCGLEIASWSEMTT 130


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 34/136 (25%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEE--------------KKKEKSK---EKIK- 86
           SS+SS DS++E+++  K +  ++ R ++  E              KKK+KSK   EK K 
Sbjct: 104 SSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163

Query: 87  ---LKKKRK----------RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKK 133
              L KKRK           S S S   E+   +KK+  +++EK  EK  K KK   HKK
Sbjct: 164 IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK---HKK 220

Query: 134 EKKKRKKEKHSSTPNS 149
             KK+KK+  SS+P+S
Sbjct: 221 HSKKKKKKAASSSPDS 236



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 14/106 (13%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKI--------------KLKKKRKRSYSSSS 99
           E+ ++ +K  A  E+++NE  +K+ EK +EK+              K +KK+   YSSSS
Sbjct: 39  EKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSS 98

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSS 145
           +    S       + ++KK+ K+ K KK + HK  +    + +  S
Sbjct: 99  SSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 144



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 43/70 (61%)

Query: 84  KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKH 143
           K +L+KK+K S + +  EE  ++  K++ +K  +K    S+S   K  +K+K+K+K  ++
Sbjct: 35  KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 94

Query: 144 SSTPNSSEFS 153
           SS+ +SS  S
Sbjct: 95  SSSSSSSSDS 104



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 20/113 (17%)

Query: 53  DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112
           +E  E+L K +    K + E EEK  E  K++++  +++  S S SS+       KK++ 
Sbjct: 32  EEVKEQLEKKKK-GSKALAEFEEKMNENWKKELEKHREKLLSGSESSS-------KKRQR 83

Query: 113 QKKEKKK------------EKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
           +KKEKKK            +  S S   +   K++ KR+K+K + +  SSE S
Sbjct: 84  KKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 136



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 68  KRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKK 127
           + + E+ EKKK+ SK   + ++K   ++      E   ++     +   KK+++K K KK
Sbjct: 32  EEVKEQLEKKKKGSKALAEFEEKMNENWKKEL--EKHREKLLSGSESSSKKRQRKKKEKK 89

Query: 128 GKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
                        +  SS+ +S +  +K
Sbjct: 90  KSGRYSSSSSSSSDSSSSSSDSEDEDKK 117



 Score = 28.9 bits (63), Expect = 1.9
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 39  DIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSS 98
           D  L   S S  +  EE     K  + + ++  E+ +KKK+  K     KKK+K++ SSS
Sbjct: 177 DKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHS---KKKKKKAASSS 233



 Score = 26.9 bits (58), Expect = 7.0
 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 4/63 (6%)

Query: 85  IKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK----KRKK 140
           I + + R    SS  T +D   + +  +++ +++ EKK K  K     +EK     K++ 
Sbjct: 4   IAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKEL 63

Query: 141 EKH 143
           EKH
Sbjct: 64  EKH 66


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 34/136 (25%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEE--------------KKKEKSK---EKIK- 86
           SS+SS DS++E+++  K +  ++ R ++  E              KKK+KSK   EK K 
Sbjct: 114 SSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173

Query: 87  ---LKKKRK----------RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKK 133
              L KKRK           S S S   E+   +KK+  +++EK  EK  K KK   HKK
Sbjct: 174 IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK---HKK 230

Query: 134 EKKKRKKEKHSSTPNS 149
             KK+KK+  SS+P+S
Sbjct: 231 HSKKKKKKAASSSPDS 246



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 14/106 (13%)

Query: 54  EENEELNKLQALQEKRINEEEEKKKEKSKEKI--------------KLKKKRKRSYSSSS 99
           E+ ++ +K  A  E+++NE  +K+ EK +EK+              K +KK+   YSSSS
Sbjct: 49  EKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSS 108

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSS 145
           +    S       + ++KK+ K+ K KK + HK  +    + +  S
Sbjct: 109 SSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 154



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 43/70 (61%)

Query: 84  KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKH 143
           K +L+KK+K S + +  EE  ++  K++ +K  +K    S+S   K  +K+K+K+K  ++
Sbjct: 45  KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 104

Query: 144 SSTPNSSEFS 153
           SS+ +SS  S
Sbjct: 105 SSSSSSSSDS 114



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 20/113 (17%)

Query: 53  DEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY 112
           +E  E+L K +    K + E EEK  E  K++++  +++  S S SS+       KK++ 
Sbjct: 42  EEVKEQLEKKKK-GSKALAEFEEKMNENWKKELEKHREKLLSGSESSS-------KKRQR 93

Query: 113 QKKEKKK------------EKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
           +KKEKKK            +  S S   +   K++ KR+K+K + +  SSE S
Sbjct: 94  KKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 146



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 68  KRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKK 127
           + + E+ EKKK+ SK   + ++K   ++      E   ++     +   KK+++K K KK
Sbjct: 42  EEVKEQLEKKKKGSKALAEFEEKMNENWKKEL--EKHREKLLSGSESSSKKRQRKKKEKK 99

Query: 128 GKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
                        +  SS+ +S +  +K
Sbjct: 100 KSGRYSSSSSSSSDSSSSSSDSEDEDKK 127



 Score = 28.9 bits (63), Expect = 1.9
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 39  DIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSS 98
           D  L   S S  +  EE     K  + + ++  E+ +KKK+  K     KKK+K++ SSS
Sbjct: 187 DKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHS---KKKKKKAASSS 243



 Score = 26.9 bits (58), Expect = 7.0
 Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 4/63 (6%)

Query: 85  IKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK----KRKK 140
           I + + R    SS  T +D   + +  +++ +++ EKK K  K     +EK     K++ 
Sbjct: 14  IAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKEL 73

Query: 141 EKH 143
           EKH
Sbjct: 74  EKH 76


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 37/121 (30%), Positives = 67/121 (55%), Gaps = 12/121 (9%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S +   +  E++ + + ++EK   +E E++KE+ KEK + K K +        E+D  
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430

Query: 106 K---QKKQKYQKKEKKKEKKSKSKKGKHHKKEK-----KKRKKEKHSSTP----NSSEFS 153
           K   ++++K  +K++ KEK+ +  K K  +K++     +KRKK+K S TP    N+S  S
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 490

Query: 154 R 154
           R
Sbjct: 491 R 491



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/133 (21%), Positives = 67/133 (50%), Gaps = 19/133 (14%)

Query: 38  RDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSS 97
           R+ + +      +D ++E E   + +  +E+  N++ +K++EK +EK K K + +     
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440

Query: 98  SSTEEDTSKQKKQKYQK-----------KEKKKEKKSK--------SKKGKHHKKEKKKR 138
              + D  K+K+Q  +K           +++KK+KKS+        S++ +   +E+++R
Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500

Query: 139 KKEKHSSTPNSSE 151
           +    S +P +S+
Sbjct: 501 RSRSSSRSPRTSK 513



 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 15/134 (11%)

Query: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK-- 92
           D +R+   +       + + E E        +EK  ++E+E++K++SKE  + +KK K  
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 477

Query: 93  ----RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK---------HHKKEKKKRK 139
               RSY++S     +S++++++  +   +  + SK+ K K          +KK+KK+ K
Sbjct: 478 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537

Query: 140 KEKHSSTPNSSEFS 153
           +  H S     E S
Sbjct: 538 ERDHISERRERERS 551



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S      ++ E  K ++    R   ++ ++K K KE++K K + K        E++  
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410

Query: 106 KQK-----KQKYQKKEKKKEKKSKSKKGKHHKKEK-----KKRKKEKHSSTPNSSEFSRK 155
           + K     K++ + +EK KEK  + ++ K H+K++     K++ KEK      S E   K
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470



 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 8/118 (6%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           SS+ S    + ++  ++ ++    R + ++++++ KS  K + K + +R   S S   D 
Sbjct: 318 SSSKSHSRRKRSQSKHRSRSHNRSR-SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKK-------RKKEKHSSTPNSSEFSRK 155
            K  ++K ++KE+ KEK  + ++ +  ++EK+K       R KE+        E  R+
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 33/134 (24%), Positives = 66/134 (49%), Gaps = 21/134 (15%)

Query: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKE----------- 83
           D ++D   +      +D D+E E+    +  +EK  ++E ++K++K K+           
Sbjct: 428 DKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487

Query: 84  ---KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEK----K 136
              +   +++R+R   SSS    TSK  K   +K  +    +S++KK K  +KE+    +
Sbjct: 488 RRSRSSSRERRRRRSRSSSRSPRTSKTIK---RKSSRSPSPRSRNKKDKKREKERDHISE 544

Query: 137 KRKKEKHSSTPNSS 150
           +R++E+ +S   SS
Sbjct: 545 RRERERSTSMRKSS 558



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 67  EKRINEEEEKKKEKSKEKIKLKKKRKRSYS---SSSTEEDTSKQKKQKYQKKEKKKEKKS 123
           E++        + KS+   K   +RKRS S   S S     S+QK ++  K   KK  KS
Sbjct: 302 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361

Query: 124 KSKK---GKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           + ++    + H ++K+K  +EK        E  R+
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 396



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 15/101 (14%)

Query: 66  QEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK------------QKKQKYQ 113
           +++R ++   KK+ KS+E+   +K R RS+S    ++   K            +K+++ +
Sbjct: 346 KDRRRSKSPHKKRSKSRER---RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 402

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
           K+ +K++++ K+K     +++ +++ KEK        E  +
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 9/66 (13%)

Query: 69  RINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKG 128
           R   +++KK+EK ++ I  +++R+RS         TS +K    +  ++K EK S S K 
Sbjct: 526 RSRNKKDKKREKERDHISERRERERS---------TSMRKSSNDRDGKEKLEKNSTSLKE 576

Query: 129 KHHKKE 134
           K H KE
Sbjct: 577 KEHNKE 582



 Score = 35.0 bits (79), Expect = 0.026
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 80  KSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
           K  E++  + +  +S+ S++ E ++ K  ++K  +       KS+S    H    ++KR 
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH---SRRKRS 329

Query: 140 KEKHSSTPNSSEFSRK 155
           + KH S  ++   SR+
Sbjct: 330 QSKHRSRSHNRSRSRQ 345



 Score = 34.3 bits (77), Expect = 0.044
 Identities = 24/120 (20%), Positives = 50/120 (41%), Gaps = 7/120 (5%)

Query: 32  LRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKR 91
           L+++   + ++     + + + +E EE+ K     +  I+   E +  KS E       R
Sbjct: 251 LKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNE-------R 303

Query: 92  KRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           K   S S T   +    K   ++K  + + +S+S      +++ ++R K  H     S E
Sbjct: 304 KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRE 363



 Score = 33.9 bits (76), Expect = 0.058
 Identities = 27/120 (22%), Positives = 49/120 (40%), Gaps = 10/120 (8%)

Query: 44  VSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE- 102
           +S+    +S + NE          +  ++     K  S+ K    K R RS++ S + + 
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTR--SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 346

Query: 103 ----DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEK---KKRKKEKHSSTPNSSEFSRK 155
                 S  KK+   ++ +K   +S S+  +   +EK   K+R KEK        E  R+
Sbjct: 347 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 406


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 37/121 (30%), Positives = 67/121 (55%), Gaps = 12/121 (9%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S +   +  E++ + + ++EK   +E E++KE+ KEK + K K +        E+D  
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314

Query: 106 K---QKKQKYQKKEKKKEKKSKSKKGKHHKKEK-----KKRKKEKHSSTP----NSSEFS 153
           K   ++++K  +K++ KEK+ +  K K  +K++     +KRKK+K S TP    N+S  S
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 374

Query: 154 R 154
           R
Sbjct: 375 R 375



 Score = 53.5 bits (127), Expect = 7e-08
 Identities = 29/133 (21%), Positives = 67/133 (50%), Gaps = 19/133 (14%)

Query: 38  RDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSS 97
           R+ + +      +D ++E E   + +  +E+  N++ +K++EK +EK K K + +     
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324

Query: 98  SSTEEDTSKQKKQKYQK-----------KEKKKEKKSK--------SKKGKHHKKEKKKR 138
              + D  K+K+Q  +K           +++KK+KKS+        S++ +   +E+++R
Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384

Query: 139 KKEKHSSTPNSSE 151
           +    S +P +S+
Sbjct: 385 RSRSSSRSPRTSK 397



 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 15/134 (11%)

Query: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK-- 92
           D +R+   +       + + E E        +EK  ++E+E++K++SKE  + +KK K  
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 361

Query: 93  ----RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK---------HHKKEKKKRK 139
               RSY++S     +S++++++  +   +  + SK+ K K          +KK+KK+ K
Sbjct: 362 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421

Query: 140 KEKHSSTPNSSEFS 153
           +  H S     E S
Sbjct: 422 ERDHISERRERERS 435



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S      ++ E  K ++    R   ++ ++K K KE++K K + K        E++  
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294

Query: 106 KQK-----KQKYQKKEKKKEKKSKSKKGKHHKKEK-----KKRKKEKHSSTPNSSEFSRK 155
           + K     K++ + +EK KEK  + ++ K H+K++     K++ KEK      S E   K
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354



 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 8/118 (6%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           SS+ S    + ++  ++ ++    R + ++++++ KS  K + K + +R   S S   D 
Sbjct: 202 SSSKSHSRRKRSQSKHRSRSHNRSR-SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKK-------RKKEKHSSTPNSSEFSRK 155
            K  ++K ++KE+ KEK  + ++ +  ++EK+K       R KE+        E  R+
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 33/134 (24%), Positives = 66/134 (49%), Gaps = 21/134 (15%)

Query: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKE----------- 83
           D ++D   +      +D D+E E+    +  +EK  ++E ++K++K K+           
Sbjct: 312 DKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371

Query: 84  ---KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEK----K 136
              +   +++R+R   SSS    TSK  K   +K  +    +S++KK K  +KE+    +
Sbjct: 372 RRSRSSSRERRRRRSRSSSRSPRTSKTIK---RKSSRSPSPRSRNKKDKKREKERDHISE 428

Query: 137 KRKKEKHSSTPNSS 150
           +R++E+ +S   SS
Sbjct: 429 RRERERSTSMRKSS 442



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 67  EKRINEEEEKKKEKSKEKIKLKKKRKRSYS---SSSTEEDTSKQKKQKYQKKEKKKEKKS 123
           E++        + KS+   K   +RKRS S   S S     S+QK ++  K   KK  KS
Sbjct: 186 ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245

Query: 124 KSKK---GKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           + ++    + H ++K+K  +EK        E  R+
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 280



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 21/101 (20%), Positives = 52/101 (51%), Gaps = 15/101 (14%)

Query: 66  QEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK------------QKKQKYQ 113
           +++R ++   KK+ KS+E+   +K R RS+S    ++   K            +K+++ +
Sbjct: 230 KDRRRSKSPHKKRSKSRER---RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 286

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
           K+ +K++++ K+K     +++ +++ KEK        E  +
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 9/66 (13%)

Query: 69  RINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKG 128
           R   +++KK+EK ++ I  +++R+RS         TS +K    +  ++K EK S S K 
Sbjct: 410 RSRNKKDKKREKERDHISERRERERS---------TSMRKSSNDRDGKEKLEKNSTSLKE 460

Query: 129 KHHKKE 134
           K H KE
Sbjct: 461 KEHNKE 466



 Score = 35.0 bits (79), Expect = 0.026
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 80  KSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
           K  E++  + +  +S+ S++ E ++ K  ++K  +       KS+S    H    ++KR 
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH---SRRKRS 213

Query: 140 KEKHSSTPNSSEFSRK 155
           + KH S  ++   SR+
Sbjct: 214 QSKHRSRSHNRSRSRQ 229



 Score = 34.3 bits (77), Expect = 0.044
 Identities = 24/120 (20%), Positives = 50/120 (41%), Gaps = 7/120 (5%)

Query: 32  LRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKR 91
           L+++   + ++     + + + +E EE+ K     +  I+   E +  KS E       R
Sbjct: 135 LKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNE-------R 187

Query: 92  KRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           K   S S T   +    K   ++K  + + +S+S      +++ ++R K  H     S E
Sbjct: 188 KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRE 247



 Score = 33.9 bits (76), Expect = 0.058
 Identities = 27/120 (22%), Positives = 49/120 (40%), Gaps = 10/120 (8%)

Query: 44  VSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE- 102
           +S+    +S + NE          +  ++     K  S+ K    K R RS++ S + + 
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTR--SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 230

Query: 103 ----DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEK---KKRKKEKHSSTPNSSEFSRK 155
                 S  KK+   ++ +K   +S S+  +   +EK   K+R KEK        E  R+
Sbjct: 231 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 290


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 53/169 (31%), Positives = 78/169 (46%), Gaps = 49/169 (28%)

Query: 29  RNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQE----KRINEEEEKKKEKSKEK 84
           RN    DP ++ V      S  + D E E L  L   Q+    ++++  E+KKK+K ++K
Sbjct: 188 RNLTANDPSQEYV-----ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKK 242

Query: 85  IKLKKKRKR-------------SYSSSSTE--------EDTSKQKKQKYQKKEKKK---- 119
            K +K R +             S SSSSTE        E  +K+KK + +K++K K    
Sbjct: 243 KKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGH 302

Query: 120 -----EKKSKSKKGK--------HHKKEKKKRKKE--KHSSTPNSSEFS 153
                E+K KSKK K        HH +EK K K    KH S+   S++S
Sbjct: 303 NNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWS 351



 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 10/121 (8%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRI--NEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE 102
           SST + +S  E+E  NK + +Q K+   N+        S+EK K KK++     SSS   
Sbjct: 269 SSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHN 328

Query: 103 DTSKQKKQKYQKKEKKKEKKSKS-----KKGKHHKKEKKKR---KKEKHSSTPNSSEFSR 154
               ++K ++ K E  +E    S     KK + HK   +KR   +KE  S +    E SR
Sbjct: 329 REKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSR 388

Query: 155 K 155
           +
Sbjct: 389 R 389



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 26/122 (21%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           SS+SS  S  E  E +          +E E   KEK  ++ K +KK K S  ++S  E+ 
Sbjct: 262 SSSSSSSSSTETSESS----------SESESNNKEKKIQR-KKRKKNKCSGHNNSDSEEK 310

Query: 105 SKQKKQK--------YQKKEKKKEK-------KSKSKKGKHHKKEKKKRKKEKHSSTPNS 149
            K KK+K        +  +EK KEK        S+      H    KK +  KHS     
Sbjct: 311 DKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG 370

Query: 150 SE 151
           SE
Sbjct: 371 SE 372



 Score = 33.1 bits (74), Expect = 0.098
 Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 12/121 (9%)

Query: 45  SSTSSEDSDEE-----NEELNKLQALQEKRINEEEEKKKEKSKEKIKL------KKKRKR 93
           +++ SE+ D+      +EEL+     +EK   +    K E S+E  K       KK R  
Sbjct: 303 NNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTH 362

Query: 94  SYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
            +S      +  +   + + ++E+ +  +S+S  G + ++E +KR +       +    S
Sbjct: 363 KHSPEKRGSERKEGSSRSHGREERSRRSRSRS-PGSYKQRETRKRAQRNPGEEQSRRNDS 421

Query: 154 R 154
           R
Sbjct: 422 R 422



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 20/95 (21%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSS--STEEDT 104
           +S EDS   + + +K     +    +   ++KE S      +++ +RS S S  S ++  
Sbjct: 343 SSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRE 402

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
           ++++ Q+   +E+ +   S+S     ++ EK  R+
Sbjct: 403 TRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 9/118 (7%)

Query: 37  KRDIVLDVSSTSSEDSDEENEELNKLQALQEKR--INEEEEKKKEKSKEKIK--LKKKRK 92
           K   V   +    ED  EE E+  K  A +E +  I +EE+ KKE+ K+++K  +KK+ K
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEK 693

Query: 93  RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKE-KHSSTPNS 149
           +       +E   K+ K    K+ KK+EKK   K+ K  KKE KK  K+ K SSTP S
Sbjct: 694 KEPKKEVKKETPPKEVK----KEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLS 747



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 7/102 (6%)

Query: 48  SSEDSDEENEELNKLQA--LQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S E+      E+ + QA  ++ K   E+  KK+ K K + K ++K K     +  E+ T 
Sbjct: 609 SKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTP 668

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTP 147
            +K++K +K+E KKE K + K     K+EKK+ KKE    TP
Sbjct: 669 IKKEEKPKKEEVKKEVKKEIK-----KEEKKEPKKEVKKETP 705



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 32/102 (31%), Positives = 55/102 (53%), Gaps = 7/102 (6%)

Query: 61  KLQALQEKRINEE-----EEKKKEKSKEKIKLKKKRKRS--YSSSSTEEDTSKQKKQKYQ 113
           K +A +EK + +E     E+KK+EK K K ++ KK  ++        +++  K++ +K  
Sbjct: 629 KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEI 688

Query: 114 KKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           KKE+KKE K + KK    K+ KK+ KKE+        +  +K
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKK 730



 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 12/119 (10%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           S +  ++S EE  E+ K+  +++    E +EK   K  + IK + K   +     ++E+ 
Sbjct: 554 SKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEP 613

Query: 105 SKQKKQKYQK----------KEK--KKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           S  K +  +K          KEK  KKE K K +  K  K++ KK   +K   TP   E
Sbjct: 614 SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE 672



 Score = 36.2 bits (82), Expect = 0.012
 Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 4/115 (3%)

Query: 37  KRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKE-KIKLKKKRKRSY 95
           K++    +        +E  +E+ K    +EK+  ++E KK+   KE K ++KK+ K+  
Sbjct: 662 KKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEV 721

Query: 96  SSSSTEEDTSKQKKQKYQKKEK---KKEKKSKSKKGKHHKKEKKKRKKEKHSSTP 147
                E     +K  K  KK      + KK  + K K  KKE+  +K    +  P
Sbjct: 722 KKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKP 776



 Score = 36.2 bits (82), Expect = 0.012
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK---RSYSSSSTEEDTSK 106
           E+  E  +E+ K    +E +   ++E+KKE  KE+ + KK+ K   +    SST    +K
Sbjct: 691 EEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAK 750

Query: 107 QKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
           +      K  KK+E   K        KEK K K
Sbjct: 751 KPAALKPKVPKKEESVKKDSVAAGKPKEKGKIK 783



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 5/112 (4%)

Query: 32  LRVDPKRDIVLDVSSTSSEDSDEEN--EELNKLQALQEKRINEEEEKKKEKSKEKIKLKK 89
           ++ + K++I  +      ++  +E   +E+ K    +EK+  ++EE  KE  KE  KL K
Sbjct: 680 VKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEE--KEPKKEIKKLPK 737

Query: 90  KRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKE 141
             K+S S+  +E       K K  KKE+  +K S +      K + K  KKE
Sbjct: 738 DAKKS-STPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKE 788



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 18/99 (18%), Positives = 48/99 (48%)

Query: 45   SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
            + T   +  EE+ E +   +  +    E+EE  K ++   I+ K++   S    + E+  
Sbjct: 946  AETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMD 1005

Query: 105  SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKH 143
               +K + ++ E++ +++ K++  +  + E +K + E +
Sbjct: 1006 EAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDY 1044



 Score = 31.6 bits (70), Expect = 0.29
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 16/92 (17%)

Query: 78   KEKSKEKIKLKKKRKRSYSSSSTEEDTSKQK-----------KQKYQK-----KEKKKEK 121
            K+  KEK K KK   ++ SSS  ++   K K           K+   K       KKKE 
Sbjct: 2236 KKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKES 2295

Query: 122  KSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
              K+ K     + K  R +EK   T N++  S
Sbjct: 2296 VEKAAKPTTTPEVKAARGEEKDKETKNAANAS 2327



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 12/96 (12%)

Query: 70  INEEEEKKKEKSKEKIK-----LKKKRKRSYSSSSTEEDTSK---QKKQKYQKKEKKKEK 121
           + + + K++  S+E +K     L  K  R  S   T E T     +K  K + KEK   K
Sbjct: 530 VKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVK 589

Query: 122 KSKSKKG--KHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           K K  K   K    EK+   KE+ S  P  +E + K
Sbjct: 590 KDKPIKTETKPSVTEKEVPSKEEPS--PVKAEVAEK 623



 Score = 26.9 bits (58), Expect = 7.0
 Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 5/102 (4%)

Query: 50   EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
            ED     EE ++    +EK   EE E+ +E  +E + +   +      S TE++ S + +
Sbjct: 927  EDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASK-----HSPTEDEESAKAE 981

Query: 110  QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
                 +EK++   S   + +    E  ++ + + S      E
Sbjct: 982  ADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEE 1023



 Score = 26.6 bits (57), Expect = 9.2
 Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 37   KRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSY 95
            KR+ V      + ED D   E + K +A Q +   +EE+K ++  +E+ + +K     Y
Sbjct: 989  KRESVASGDDRAEEDMD---EAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDY 1044


>gi|21361576 zinc finger, CCHC domain containing 17 [Homo sapiens]
          Length = 241

 Score = 56.6 bits (135), Expect = 8e-09
 Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 13/122 (10%)

Query: 15  CKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEE 74
           CKKCG  GH   +C  F++    +  ++        D +EE EE    +  ++       
Sbjct: 133 CKKCGCKGHFAKDC--FMQPGGTKYSLIP-------DEEEEKEEAKSAE-FEKPDPTRNP 182

Query: 75  EKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKE 134
            +K++K K+K K + ++     SS +E DT   K+ ++  K+ K  KK K KK KH KK 
Sbjct: 183 SRKRKKEKKKKKHRDRKSSDSDSSDSESDTG--KRARHTSKDSKAAKKKKKKK-KHKKKH 239

Query: 135 KK 136
           K+
Sbjct: 240 KE 241



 Score = 30.0 bits (66), Expect = 0.83
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 95  YSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           YS    EE+  ++ K    + EK    ++ S+K K  KK+KK R ++   S  + SE
Sbjct: 155 YSLIPDEEEEKEEAKSA--EFEKPDPTRNPSRKRKKEKKKKKHRDRKSSDSDSSDSE 209


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 5/112 (4%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEE----EKKKEKSKEKIKLKKKRKRSYSSSSTE 101
           S S  DSD+++    K +   E R   E     E ++   K K   KK +KR + S S E
Sbjct: 801 SRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPE 860

Query: 102 EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
            D  ++K +K + +E +K++  +  + K HK  KKK  K+  +   + SE S
Sbjct: 861 SDAEREKDKKEKDRESEKDRTRQRSESK-HKSPKKKTGKDSGNWDTSGSELS 911



 Score = 53.1 bits (126), Expect = 9e-08
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 67  EKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSK 126
           E        K K+ SK+  K  +KR RS S S +++D S  KK++ + + +   + S S 
Sbjct: 774 EHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833

Query: 127 KG----KHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +     K  KK KKK KK +H S    S+  R+
Sbjct: 834 ESERSYKKSKKHKKKSKKRRHKSDSPESDAERE 866



 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 10/113 (8%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSK---EKIKLKKKRKRSYSSSSTEEDTSK 106
           E   + +   NK  + + K+ + +  + +  S    +    KKKR+RS S S++E  +S 
Sbjct: 774 EHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833

Query: 107 QKKQKYQKKEKKKEKKSKSKKGKHH------KKEKKKRKKEKHSSTPNSSEFS 153
           + ++ Y KK KK +KKSK ++ K        ++EK K++K++ S    + + S
Sbjct: 834 ESERSY-KKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRS 885



 Score = 35.0 bits (79), Expect = 0.026
 Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 27/138 (19%)

Query: 44  VSSTSSEDSDEENEELNKLQALQEKRINEEEEKK-----------KEKSKEKIKLKKKRK 92
           +   S E S    EE +K + + +    +EEE+            KE++K+  K   K K
Sbjct: 321 IQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEK 380

Query: 93  RSYSSSSTEEDTS--------------KQKKQKYQ--KKEKKKEKKSKSKKGKHHKKEKK 136
           R  S++S E+                  +KKQ +   K + +KE+K +++      KE  
Sbjct: 381 RVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESF 440

Query: 137 KRKKEKHSSTPNSSEFSR 154
           +R  E H    +++ + +
Sbjct: 441 QRFLENHEKMTSTTRYKK 458



 Score = 31.2 bits (69), Expect = 0.37
 Identities = 37/167 (22%), Positives = 62/167 (37%), Gaps = 50/167 (29%)

Query: 39  DIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSK---------------- 82
           D V  +SST    + +         +L EK    E E++KE+++                
Sbjct: 671 DFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQA 730

Query: 83  -----------------------EKIKLKKKRKRSYSS----SSTEEDTSKQKKQKYQKK 115
                                  E I L+ +RKR +         E      K +K+ KK
Sbjct: 731 APPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKK 790

Query: 116 EKK-KEKKSKSKKGK------HHKKEKKKRKKEKHSSTPNSSEFSRK 155
            KK   K+S+S+ G        H K+K++R + + +S  +SS  S +
Sbjct: 791 SKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837



 Score = 30.0 bits (66), Expect = 0.83
 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 52  SDEENEELNKLQALQEKRI----NEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE-DTSK 106
           S EE  +L    A+Q++ +    N  EE  K+++      KK+ + S  +  T   +T +
Sbjct: 308 STEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKE 367

Query: 107 QKKQKYQKKEKKKEKKSKS 125
           + KQ +  KE  KEK+  S
Sbjct: 368 EAKQAF--KELLKEKRVPS 384


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 6/80 (7%)

Query: 76  KKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKH----- 130
           K K K +EK + K     S SSS ++  +  Q        E   E+KSK +K KH     
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239

Query: 131 -HKKEKKKRKKEKHSSTPNS 149
            HKKEKKKRKK K S++  S
Sbjct: 240 KHKKEKKKRKKSKKSASSES 259



 Score = 51.6 bits (122), Expect = 3e-07
 Identities = 32/123 (26%), Positives = 65/123 (52%), Gaps = 3/123 (2%)

Query: 31  FLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQA--LQEKRINEEEEKKKEKSKEKIKLK 88
           F +V   +++V ++ +  ++ + +   E+  L    L  K   ++EEKK+ KS       
Sbjct: 141 FGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSS 200

Query: 89  KKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPN 148
                S S S +  D+S  +    +K +K+K+K  K+ + KH K++KK++K +K +S+ +
Sbjct: 201 SSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR-KHKKEKKKRKKSKKSASSES 259

Query: 149 SSE 151
            +E
Sbjct: 260 EAE 262



 Score = 50.4 bits (119), Expect = 6e-07
 Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 20/127 (15%)

Query: 48  SSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQ 107
           +SE  D+   ++ K    + +  ++E+ K KE+  +  + ++KR RS S     E+  ++
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500

Query: 108 KKQKYQK---------KEKKKEKKSKSKKGKHHKKEKKKRK-----------KEKHSSTP 147
           +KQ   K         KEK K+ +SKS +  H K ++K R+           K KHS   
Sbjct: 501 EKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNS 560

Query: 148 NSSEFSR 154
            + E SR
Sbjct: 561 RTRERSR 567



 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 9/124 (7%)

Query: 33  RVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK 92
           R + K   V D  S S E     N E +      +K  N+ +++ K KS+ K K K K K
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKD------DKYKNKVKKRAKSKSRSKSKEKSKSK 471

Query: 93  RSYSSSSTEEDTSKQKKQKYQKKE--KKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSS 150
              S  +  E+   + + K +  E  K+KEK+S S KGK  ++ + K K ++  S  N  
Sbjct: 472 ERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDS-KGKDQERSRSKEKSKQLESKSNEH 530

Query: 151 EFSR 154
           + S+
Sbjct: 531 DHSK 534



 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 14/133 (10%)

Query: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKS--------KEKIK 86
           + KR      SS+SS DSD  ++  +   +   +   EE+ KK++K         K++ K
Sbjct: 187 EKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKK 246

Query: 87  LKKKRKRSYSSSSTEEDTSKQKKQKYQKK------EKKKEKKSKSKKGKHHKKEKKKRKK 140
            +KK K+S SS S  E+   Q +   + +      E +   +    K    +++ ++R++
Sbjct: 247 KRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERER 306

Query: 141 EKHSSTPNSSEFS 153
           E+  + PNS   S
Sbjct: 307 ERECNPPNSQPAS 319



 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 5/111 (4%)

Query: 49  SEDSDEENEELNKLQALQEKRINEEEEKKKEKS-KEKIKLKKKRKRSYSSSSTEEDTSKQ 107
           SE  + +NE+  K++  +      +  +  EK  K K K+KK+ K    S S E+  SK+
Sbjct: 413 SESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKE 472

Query: 108 KKQKYQKKEKKKEKKSKSKKGKHH---KKEKKKRKKEKHSSTPNSSEFSRK 155
           +  K+ + E+K+  +S+SK   H    +KEK+   K K      S E S++
Sbjct: 473 RDSKHNRNEEKR-MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ 522



 Score = 43.5 bits (101), Expect = 7e-05
 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 9/107 (8%)

Query: 55  ENEELNKLQALQEKRINEEEEKKKE-----KSKEKIKLKKKRKRSYSSSSTEEDTSK--Q 107
           +  ELN+++  Q   +  +E K  +     +S  +   K+K+ + + S+S E D  +  +
Sbjct: 384 DKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE 443

Query: 108 KKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
           K  KY+ K KK+ K     K K  +K K K +  KH+        SR
Sbjct: 444 KDDKYKNKVKKRAKSKSRSKSK--EKSKSKERDSKHNRNEEKRMRSR 488



 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           S +S    + E+E+    ++      N   EKK ++ +      K+     SS   E  +
Sbjct: 649 SKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ-----SSQDNELKS 703

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           S  K ++ +K     EK+++  KG+ +    +K KK  H S+P + E
Sbjct: 704 SMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDE 750



 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 10/122 (8%)

Query: 38  RDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSS 97
           RD    V S + +     ++E ++ +  + +R      +++     + + K +R+R   S
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDS 628

Query: 98  SSTE-EDTSKQKKQKYQKKEKK---------KEKKSKSKKGKHHKKEKKKRKKEKHSSTP 147
            S+E E++  + K KY+ +E K          EK+  SK   H+     + KK     +P
Sbjct: 629 RSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSP 688

Query: 148 NS 149
            S
Sbjct: 689 FS 690



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 22/100 (22%), Positives = 50/100 (50%), Gaps = 4/100 (4%)

Query: 48  SSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK-RSYSSSSTEEDTSK 106
           S  + +EE    ++ +    + + E+E++   K K++ + + K K +   S S E D SK
Sbjct: 475 SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSK 534

Query: 107 QKKQKYQKKEKKKEKKSKSKKGKH-HKKEKKKRKKEKHSS 145
            K++   ++ + + ++    KGKH +    ++R + +  S
Sbjct: 535 SKEK--DRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS 572



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 23/138 (16%), Positives = 58/138 (42%), Gaps = 29/138 (21%)

Query: 47  TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKK------KRKRSYSSSST 100
           + S+  D+E     +     E + NE +  K ++   + + +       K K SY+S + 
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563

Query: 101 EEDTSKQ-----------------------KKQKYQKKEKKKEKKSKSKKGKHHKKEKKK 137
           E   S+                        ++Q+Y+++ + + ++ ++  G+   K++++
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623

Query: 138 RKKEKHSSTPNSSEFSRK 155
           R+++  SS    S+   K
Sbjct: 624 RRRDSRSSEREESQSRNK 641



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 7/76 (9%)

Query: 80  KSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
           KSK K + KK+ K S SSSS+  D+           + +    S   +    +K KK++K
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSS-------DSQSSSDSSDSESATEEKSKKRKK 232

Query: 140 KEKHSSTPNSSEFSRK 155
           K + +S  +  E  ++
Sbjct: 233 KHRKNSRKHKKEKKKR 248



 Score = 30.0 bits (66), Expect = 0.83
 Identities = 15/81 (18%), Positives = 35/81 (43%)

Query: 71  NEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKH 130
           + E E+ + ++K+K + ++ +      +S  E     K + +      +EKK+   +   
Sbjct: 630 SSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPF 689

Query: 131 HKKEKKKRKKEKHSSTPNSSE 151
            K ++  +  E  SS   + E
Sbjct: 690 SKIKQSSQDNELKSSMLKNKE 710


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 38/129 (29%), Positives = 60/129 (46%), Gaps = 19/129 (14%)

Query: 39  DIVLDVSSTSSEDSDEENEELNK-LQALQ---------------EKRINEEEEKKKEKSK 82
           DIV +    ++  SDE++++ N   +AL                +K  N E  K  EK  
Sbjct: 775 DIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDV 834

Query: 83  EKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
             ++ K K+ +       E++  K+KK++   KEKKK  K K KK +  K+E+ K KK+ 
Sbjct: 835 PMVEKKSKKPKKKEKKHKEKERDKEKKKE---KEKKKSPKPKKKKHRKEKEERTKGKKKS 891

Query: 143 HSSTPNSSE 151
               P S E
Sbjct: 892 KKQPPGSEE 900



 Score = 43.1 bits (100), Expect = 9e-05
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 2/119 (1%)

Query: 35  DPKR--DIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK 92
           DP R  DI LD     SE    +     +     EK +   E+K K+  K++ K K+K +
Sbjct: 797 DPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKER 856

Query: 93  RSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
                   E+  S + K+K  +KEK++  K K K  K     ++   +   +  P   +
Sbjct: 857 DKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQ 915



 Score = 37.0 bits (84), Expect = 0.007
 Identities = 38/159 (23%), Positives = 61/159 (38%), Gaps = 59/159 (37%)

Query: 56  NEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE------------- 102
           +++  KL+  +  R   E++K+++K KEK K  K+R  S  + S E+             
Sbjct: 721 SDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 780

Query: 103 -------------------------------DTSKQKKQKYQKKE------------KKK 119
                                          D+ K   QK++  E            +KK
Sbjct: 781 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKK 840

Query: 120 EKKSKSKKGKHHKKEK---KKRKKEKHSSTPNSSEFSRK 155
            KK K K+ KH +KE+   KK++KEK  S     +  RK
Sbjct: 841 SKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRK 879



 Score = 36.6 bits (83), Expect = 0.009
 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 18/107 (16%)

Query: 63  QALQEKRINEEEEKKKEKSKEKIKLKKK---RKRSYSSSSTEE------DTSKQKK---- 109
           +A +E+     E +K+E++     +K     +KR   +   E       D S   K    
Sbjct: 659 EADEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGL 718

Query: 110 ---QKYQKKEKKKEKKSKSKKGKHHKK--EKKKRKKEKHSSTPNSSE 151
               +Y K E+++  + K +K K  KK  EK+K+ K +HSS P  S+
Sbjct: 719 PMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESD 765



 Score = 27.3 bits (59), Expect = 5.4
 Identities = 16/76 (21%), Positives = 37/76 (48%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E   +E E   + +  +EK+ + + +KKK + +++ + K K+K       +EE   +  +
Sbjct: 848 EKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQ 907

Query: 110 QKYQKKEKKKEKKSKS 125
               ++E+   + S S
Sbjct: 908 NGAPEEEQLPPESSYS 923


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 31/139 (22%), Positives = 75/139 (53%), Gaps = 19/139 (13%)

Query: 21  PGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKK-- 78
           PG  T   R+FLR+               +++ E +E L + Q LQE+++ E+EE K+  
Sbjct: 347 PGESTLR-RDFLRLQ--------------QENKERSEALRRQQLLQEQQLREQEEYKRQL 391

Query: 79  --EKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK 136
             E+ K   + K++R+R       E +  +Q++++ +++E++++++ +  + +  ++E++
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451

Query: 137 KRKKEKHSSTPNSSEFSRK 155
           +R +E+        E+ R+
Sbjct: 452 RRAEEEKRRVEREQEYIRR 470



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 15/73 (20%), Positives = 43/73 (58%), Gaps = 5/73 (6%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E+      E  + Q  +++R  +EE+++ E+ + + K +++R+R     + EE    +++
Sbjct: 410 EEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR-----AEEEKRRVERE 464

Query: 110 QKYQKKEKKKEKK 122
           Q+Y +++ ++E++
Sbjct: 465 QEYIRRQLEEEQR 477


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 31/139 (22%), Positives = 75/139 (53%), Gaps = 19/139 (13%)

Query: 21  PGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKK-- 78
           PG  T   R+FLR+               +++ E +E L + Q LQE+++ E+EE K+  
Sbjct: 347 PGESTLR-RDFLRLQ--------------QENKERSEALRRQQLLQEQQLREQEEYKRQL 391

Query: 79  --EKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK 136
             E+ K   + K++R+R       E +  +Q++++ +++E++++++ +  + +  ++E++
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451

Query: 137 KRKKEKHSSTPNSSEFSRK 155
           +R +E+        E+ R+
Sbjct: 452 RRAEEEKRRVEREQEYIRR 470



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 15/73 (20%), Positives = 43/73 (58%), Gaps = 5/73 (6%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E+      E  + Q  +++R  +EE+++ E+ + + K +++R+R     + EE    +++
Sbjct: 410 EEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR-----AEEEKRRVERE 464

Query: 110 QKYQKKEKKKEKK 122
           Q+Y +++ ++E++
Sbjct: 465 QEYIRRQLEEEQR 477


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 31/139 (22%), Positives = 75/139 (53%), Gaps = 19/139 (13%)

Query: 21  PGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKK-- 78
           PG  T   R+FLR+               +++ E +E L + Q LQE+++ E+EE K+  
Sbjct: 347 PGESTLR-RDFLRLQ--------------QENKERSEALRRQQLLQEQQLREQEEYKRQL 391

Query: 79  --EKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK 136
             E+ K   + K++R+R       E +  +Q++++ +++E++++++ +  + +  ++E++
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEER 451

Query: 137 KRKKEKHSSTPNSSEFSRK 155
           +R +E+        E+ R+
Sbjct: 452 RRAEEEKRRVEREQEYIRR 470



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 15/73 (20%), Positives = 43/73 (58%), Gaps = 5/73 (6%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           E+      E  + Q  +++R  +EE+++ E+ + + K +++R+R     + EE    +++
Sbjct: 410 EEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR-----AEEEKRRVERE 464

Query: 110 QKYQKKEKKKEKK 122
           Q+Y +++ ++E++
Sbjct: 465 QEYIRRQLEEEQR 477


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 53.1 bits (126), Expect = 9e-08
 Identities = 35/98 (35%), Positives = 55/98 (56%), Gaps = 10/98 (10%)

Query: 55  ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQK 114
           E EE  KL+  + KR  EE +KKKE+ KE   LK+K +R       +E   KQ+ ++ ++
Sbjct: 353 EREEKEKLKE-EAKRAKEEAKKKKEEEKE---LKEKERREKREKDEKEKAEKQRLKEERR 408

Query: 115 KEK------KKEKKSKSKKGKHHKKEKKKRKKEKHSST 146
           KE+      K E+K K ++ K  ++E+K+ K EK   T
Sbjct: 409 KERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 446



 Score = 50.4 bits (119), Expect = 6e-07
 Identities = 28/91 (30%), Positives = 53/91 (58%), Gaps = 5/91 (5%)

Query: 55  ENEELNKLQALQEKRINEEEEKKKE---KSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQK 111
           + E L K   L+ +R  EE+EK KE   ++KE+ K KK+ ++        E   K +K+K
Sbjct: 340 DQERLGKQLKLRAER--EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397

Query: 112 YQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
            +K+  K+E++ + ++    K E+K++K+E+
Sbjct: 398 AEKQRLKEERRKERQEALEAKLEEKRKKEEE 428



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 26/98 (26%), Positives = 61/98 (62%), Gaps = 4/98 (4%)

Query: 58  ELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEK 117
           E NKL+  +++    ++ K + + +EK KLK++ KR+   +  +++  K+ K+K +++++
Sbjct: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390

Query: 118 KKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +K++K K++K    ++ K++R+KE+  +     E  RK
Sbjct: 391 EKDEKEKAEK----QRLKEERRKERQEALEAKLEEKRK 424



 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 27/92 (29%), Positives = 52/92 (56%), Gaps = 10/92 (10%)

Query: 61  KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEK-KK 119
           +LQ  QE+   + + + + + KEK+K + KR +  +    EE+   ++K++ +K+EK +K
Sbjct: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395

Query: 120 EKKSKSKKGKHHKKEK---------KKRKKEK 142
           EK  K +  +  +KE+         +KRKKE+
Sbjct: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEE 427



 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 21/98 (21%), Positives = 57/98 (58%), Gaps = 1/98 (1%)

Query: 32  LRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKR 91
           L++  +R+    +   +    +E  ++  + + L+EK   E+ EK +++  EK +LK++R
Sbjct: 348 LKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEER 407

Query: 92  KRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK 129
           ++     + E    +++K++ +K+ +++EK+ K++K +
Sbjct: 408 RKE-RQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444



 Score = 39.3 bits (90), Expect = 0.001
 Identities = 27/117 (23%), Positives = 54/117 (46%), Gaps = 10/117 (8%)

Query: 36  PKRDIVLDVSSTSSEDSD----------EENEELNKLQALQEKRINEEEEKKKEKSKEKI 85
           P+ D VL  SS SS  S           +++   +        R   ++  K    K K+
Sbjct: 276 PEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKL 335

Query: 86  KLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
           +L++ ++R         +  +++K K + K  K+E K K ++ K  K+++++ K+EK
Sbjct: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREK 392


>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
          Length = 221

 Score = 53.1 bits (126), Expect = 9e-08
 Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 7/91 (7%)

Query: 63  QALQEKRINEEEEK----KKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKK 118
           Q L++ R+  E+      +  K  EK    ++ K+    S+++ED S     + ++K KK
Sbjct: 128 QKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKK 187

Query: 119 KEKKSKSKKGKHHKKEKKKRKKEKHSSTPNS 149
           K+KK K KK    KKEKKK+KK KH S+ ++
Sbjct: 188 KKKKEKHKK---RKKEKKKKKKRKHKSSKSN 215



 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 17/125 (13%)

Query: 6   CNKDSVRAGCKKCGY--PGHLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQ 63
           C +   R G K+C +   G+   E       DP  DI+ D          E++  + +L+
Sbjct: 108 CKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRD------NKRHEKDVRIQQLK 161

Query: 64  ALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKS 123
            L E   ++E+      S+ K K KKK+K+        E   K+KK+K +KK+K+K K S
Sbjct: 162 QLLEDSTSDEDRSSSSSSEGKEKHKKKKKK--------EKHKKRKKEK-KKKKKRKHKSS 212

Query: 124 KSKKG 128
           KS +G
Sbjct: 213 KSNEG 217



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 101 EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           E+D   Q+ ++  +     E +S S   +  +K KKK+KKEKH       +  +K
Sbjct: 152 EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKK 206


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 34/116 (29%), Positives = 65/116 (56%), Gaps = 6/116 (5%)

Query: 44  VSSTSSEDSDEENEELNK--LQALQEKRINEEEEKKKEKSKE--KIKLKKKRKRSYSSSS 99
           +S    E+ D + E+  +   +A++E      E  K++KSK+  K+K+K ++K + S  S
Sbjct: 588 MSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVKVKMEKKSTPSRGS 647

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKR--KKEKHSSTPNSSEFS 153
           + + +S+Q  + ++ KE     +S S + K  KK ++    ++E+ +STP SSE S
Sbjct: 648 SSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEELASTPPSSEDS 703



 Score = 34.7 bits (78), Expect = 0.034
 Identities = 21/104 (20%), Positives = 44/104 (42%), Gaps = 5/104 (4%)

Query: 51  DSDEEN-----EELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           DSDE+      E + +   ++E+  N+  +   E++ E     ++ +       +    S
Sbjct: 443 DSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASAS 502

Query: 106 KQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNS 149
               +    +++KK K+ K  K    +K +KK  + K    PN+
Sbjct: 503 SSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNA 546



 Score = 34.3 bits (77), Expect = 0.044
 Identities = 33/150 (22%), Positives = 58/150 (38%), Gaps = 40/150 (26%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKK------------------------EK 80
           +S+SS + D + +E  + Q  + K   + + +KK                          
Sbjct: 501 ASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNA 560

Query: 81  SKEKIK----------LKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKS------K 124
           S+EKIK          L KK    +   S E+     +K +  +++ +K  K       +
Sbjct: 561 SREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGE 620

Query: 125 SKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
           S K    KK+KK + K +  STP+    S+
Sbjct: 621 SSKRDKSKKKKKVKVKMEKKSTPSRGSSSK 650


>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
           [Homo sapiens]
          Length = 759

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 21/112 (18%)

Query: 43  DVSSTSSEDSDEEN---------EELNKLQALQEKR--------INEEEEKKKEKSKEKI 85
           D S+++SE+S+ EN         + L K    Q ++         N      K++  E+ 
Sbjct: 115 DDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEK 174

Query: 86  KLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKK 137
           K KKK K+S S    E     +KK    KK+K KEKK K +K K  K+E+KK
Sbjct: 175 KKKKKEKKSKSDDKNENKNDPEKK----KKKKDKEKKKKEEKSKDKKEEEKK 222



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 16/63 (25%), Positives = 33/63 (52%)

Query: 41  VLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSST 100
           + +V+++S++D + E ++  K +   +     E +   EK K+K   +KK+K   S    
Sbjct: 158 LFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKK 217

Query: 101 EED 103
           EE+
Sbjct: 218 EEE 220


>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
           sapiens]
          Length = 690

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 21/112 (18%)

Query: 43  DVSSTSSEDSDEEN---------EELNKLQALQEKR--------INEEEEKKKEKSKEKI 85
           D S+++SE+S+ EN         + L K    Q ++         N      K++  E+ 
Sbjct: 46  DDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEK 105

Query: 86  KLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKK 137
           K KKK K+S S    E     +KK    KK+K KEKK K +K K  K+E+KK
Sbjct: 106 KKKKKEKKSKSDDKNENKNDPEKK----KKKKDKEKKKKEEKSKDKKEEEKK 153



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 16/63 (25%), Positives = 33/63 (52%)

Query: 41  VLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSST 100
           + +V+++S++D + E ++  K +   +     E +   EK K+K   +KK+K   S    
Sbjct: 89  LFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKK 148

Query: 101 EED 103
           EE+
Sbjct: 149 EEE 151


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 7/117 (5%)

Query: 36   PKRDIVLDVSSTSSED--SDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKR 93
            PK      V    SE+  S+E    L++L+  +     EEEE+++E+ +E+ +++++ + 
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE- 2267

Query: 94   SYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSS 150
                   EE+  ++K+ + +++EKKK+KK K K+    K+E  + K+E  S     S
Sbjct: 2268 ----ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETES 2320



 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 9/99 (9%)

Query: 50   EDSDEENEELNKLQALQEKRINEEEE----KKKEKSKEKIKLKKKRKRSYSSSSTEEDT- 104
            E+  EE EE  + +  +EK++ +EEE    KKKEK KE+++ K++         +EE+T 
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319

Query: 105  ----SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRK 139
                 +++++    +E+   +K   KK K  K ++++RK
Sbjct: 2320 SLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRK 2358



 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 29/111 (26%), Positives = 56/111 (50%), Gaps = 9/111 (8%)

Query: 41   VLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSST 100
            +LD        S EE EE  + +  +E+ + EEEE++KE+ + + K  +K          
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE--------- 2283

Query: 101  EEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
            EE+  K+KK+K +++ ++KE+  + K+    ++E +    E+      S E
Sbjct: 2284 EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334



 Score = 43.9 bits (102), Expect = 6e-05
 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 7/127 (5%)

Query: 23   HLTFECRNFLRVDPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSK 82
            H + E  + L    K++ +        E+ +E  EE  + +  + K   E EEK+ EK +
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284

Query: 83   EKIKLKKKRKRSYS-------SSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEK 135
            E+ K KKK K+              EE  S+++ +    +E+++E  S  ++    K+  
Sbjct: 2285 EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344

Query: 136  KKRKKEK 142
            KK K+ K
Sbjct: 2345 KKEKQFK 2351



 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 31/88 (35%), Positives = 51/88 (57%), Gaps = 11/88 (12%)

Query: 57   EELNKLQALQEKRINEEEE---KKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQ 113
            +E  KL   +EK   EEE    K+++  ++K+KL +KR+R  +S    E+ +K K   YQ
Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM---EELTKNKMILYQ 1835

Query: 114  KKEKKKEKKSKSKKGKHHKKEKKKRKKE 141
            KK   +EKK+ ++     +KEK  ++KE
Sbjct: 1836 KKNLAQEKKNLAQ-----EKEKLAQRKE 1858



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 28/103 (27%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 50   EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
            E+   + EELN+    +E ++ EE++K  E+ +     ++K     +  + EE+   Q+K
Sbjct: 1726 EELSWKEEELNQ----EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781

Query: 110  QKY-QKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
            +K  Q KEK  E++ +  + +    EKK +  +K     NS E
Sbjct: 1782 EKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSME 1824



 Score = 38.5 bits (88), Expect = 0.002
 Identities = 26/126 (20%), Positives = 58/126 (46%), Gaps = 21/126 (16%)

Query: 51   DSDEEN--EELNKLQALQEKRINEEEEKKKEKSKEKIK-------------------LKK 89
            D +EE   EE   +  L+ +    +E K+ +K KEK                     L +
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236

Query: 90   KRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNS 149
              K+   SS  EE+  ++++++ ++  +++E++ + ++G+  + EK++ +K+K       
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296

Query: 150  SEFSRK 155
             E   K
Sbjct: 2297 EEVQEK 2302



 Score = 35.8 bits (81), Expect = 0.015
 Identities = 21/91 (23%), Positives = 49/91 (53%), Gaps = 1/91 (1%)

Query: 50   EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
            E+   E EE  K +  +EK+  EE ++K+E  +EK ++  + +    S   EE+ S   +
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKK-KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334

Query: 110  QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKK 140
            ++  ++++  +K+ + K  +  +K  + R++
Sbjct: 2335 EEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365



 Score = 34.7 bits (78), Expect = 0.034
 Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 6/91 (6%)

Query: 45   SSTS----SEDSDEENEELNKLQ-ALQEKRINEEEEKKKEKSK-EKIKLKKKRKRSYSSS 98
            SSTS    S+D D + ++++K   AL  KR+ +  +K+ +K+  +K+K K K+K   +  
Sbjct: 1142 SSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKV 1201

Query: 99   STEEDTSKQKKQKYQKKEKKKEKKSKSKKGK 129
              EE T    +Q   KK K + + +    G+
Sbjct: 1202 INEETTPPVMEQPVTKKVKIQGRGASGISGR 1232



 Score = 33.9 bits (76), Expect = 0.058
 Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 11/99 (11%)

Query: 47   TSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSK 106
            T  E+   E EE  + Q  +E+R  +EE K     +++ + +KKR +     + EE+   
Sbjct: 1545 TLEEEVSREGEEKEQ-QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603

Query: 107  QKKQKYQKKEKK----------KEKKSKSKKGKHHKKEK 135
            Q++++  ++E+K           +++    +GK  +KE+
Sbjct: 1604 QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEE 1642



 Score = 32.7 bits (73), Expect = 0.13
 Identities = 22/99 (22%), Positives = 55/99 (55%), Gaps = 13/99 (13%)

Query: 44   VSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEED 103
            +SS S E   ++ EE+     L+E+   E EEK+++ ++E+  ++++ K +         
Sbjct: 1529 LSSKSKEQQYKDEEEVT----LEEEVSREGEEKEQQVTEEQRHIQEEHKWA--------- 1575

Query: 104  TSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
               +K+ + +KK  ++E+K   ++ K  ++E++  ++E+
Sbjct: 1576 RIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEER 1614



 Score = 31.2 bits (69), Expect = 0.37
 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 7/123 (5%)

Query: 40   IVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEE--KKKEK---SKEKIKLKKKRKRS 94
            I+  V    +++ +   ++  KL   ++K +  E+   KK+EK    K K+ L+K   + 
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946

Query: 95   YSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKH--HKKEKKKRKKEKHSSTPNSSEF 152
                  E D +K++K    + ++  E+K +  +GK    K E  +  +++  +      F
Sbjct: 1947 KKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELF 2006

Query: 153  SRK 155
             RK
Sbjct: 2007 ERK 2009



 Score = 31.2 bits (69), Expect = 0.37
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 9/112 (8%)

Query: 43   DVSSTSSEDSDEENEELNKLQALQEKR---INEEEEKKKEKSKEKIKLKKKRKRSYSSSS 99
            D S   SE + +E +   K + L  K    IN+EE+  +E+SK        RK S     
Sbjct: 2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK------LARKHSEVILD 2177

Query: 100  TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
             EE+   ++++     +++  K+ ++K+G   K++   +  E  S    S E
Sbjct: 2178 DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEE 2229



 Score = 30.4 bits (67), Expect = 0.64
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 92   KRSYSSSSTEEDTSKQK----KQKYQKKEKKKEKKSKSKK-GKHHKKEKKKRKKEKHSST 146
            K S    S E+D SK       ++ QK   K++KK+ ++K  K HKK+ K+ K     +T
Sbjct: 1148 KLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETT 1207

Query: 147  P 147
            P
Sbjct: 1208 P 1208



 Score = 30.4 bits (67), Expect = 0.64
 Identities = 19/95 (20%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 53   DEENEELNKLQALQEKRINEEEEKKKEKSKE------KIKLKKKRKRSYSSSSTEEDTSK 106
            +E+  +  +  + +E+ + E+++ K E+ K+        K K+++ +     + EE+ S+
Sbjct: 1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552

Query: 107  QKKQKYQK-KEKKKEKKSKSKKGKHHKKEKKKRKK 140
            + ++K Q+  E+++  + + K  + H+K  +  KK
Sbjct: 1553 EGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587



 Score = 30.4 bits (67), Expect = 0.64
 Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 6/87 (6%)

Query: 61   KLQALQEKRINEEEEK-KKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKE--- 116
            K +A +E+++ +EEEK  +E+ ++  + ++K  ++Y   + ++    Q + K+ +KE   
Sbjct: 1586 KKRAQEERKLAQEEEKLAQEE-RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETL 1644

Query: 117  -KKKEKKSKSKKGKHHKKEKKKRKKEK 142
             ++ EK S+  +    K++K  +K EK
Sbjct: 1645 AQRGEKLSQEAEKLAQKRKKLAKKWEK 1671



 Score = 30.0 bits (66), Expect = 0.83
 Identities = 21/101 (20%), Positives = 55/101 (54%), Gaps = 8/101 (7%)

Query: 50   EDSDEENEELN--KLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSS---TEEDT 104
            E+  +E+++L   + + + E  ++ + ++++ K +E++ L+++  R         TEE  
Sbjct: 1507 EEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQR 1566

Query: 105  SKQKKQKY---QKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
              Q++ K+    +K  + EKK   ++ K  ++E+K  ++E+
Sbjct: 1567 HIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEER 1607



 Score = 29.6 bits (65), Expect = 1.1
 Identities = 24/90 (26%), Positives = 48/90 (53%), Gaps = 9/90 (10%)

Query: 54   EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKY- 112
            +E E+L    A +E+++ +EE K  +   +  +  ++  ++    + +E+T  Q+ +K  
Sbjct: 1597 QEEEKL----AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652

Query: 113  QKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
            Q+ EK  +K+ K  K    K EK  R++EK
Sbjct: 1653 QEAEKLAQKRKKLAK----KWEKVAREEEK 1678



 Score = 29.6 bits (65), Expect = 1.1
 Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 7/60 (11%)

Query: 35   DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRS 94
            + K +I+ +  + S  D +EE E  +    L+E+   E+E  KKEK   + KL+++R++S
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCS----LEEEVDREKEILKKEK---QFKLQEQRRKS 2359



 Score = 29.3 bits (64), Expect = 1.4
 Identities = 21/90 (23%), Positives = 46/90 (51%), Gaps = 7/90 (7%)

Query: 60   NKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQK-------Y 112
            NK+ A  E+++ +E+E   +K ++  + +KK  +   S + +++   Q+K K        
Sbjct: 1885 NKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMV 1944

Query: 113  QKKEKKKEKKSKSKKGKHHKKEKKKRKKEK 142
            Q K++ + +   +K+ K    E K+  +EK
Sbjct: 1945 QGKKRLRGELDIAKEEKALNLEMKRLAEEK 1974



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 73   EEEKKKEKSKEKIKLKKKR---KRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK 129
            EEE+ ++K+++ + L++ +   K+       E       K+   KKE+KK  +   K+G+
Sbjct: 1346 EEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKE-ISKKEEKKTFQKSPKQGR 1404

Query: 130  HHKKEKKKRKKEKHSSTPNSSEFSRK 155
               ++++K  K K   T    + S +
Sbjct: 1405 KAVQKERKVGKIKREMTKEERDMSEE 1430



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query: 37   KRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKR-SY 95
            K  ++L      +++     +E  KL   +E  +  +E     K K+ +++K K    + 
Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK-KQLVQVKNKLGMFNK 1886

Query: 96   SSSSTEEDTSKQKKQKYQKKEKKKEKKSK--------SKKGKHHKKEKKKRKKEK 142
              +  EE  +++K+   +KKEK  E + K        +KK +   +EK K   EK
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEK 1941



 Score = 26.6 bits (57), Expect = 9.2
 Identities = 16/81 (19%), Positives = 37/81 (45%)

Query: 73   EEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK 132
            ++EKK  + + K+  K +R  +     TEE++   +K      + ++E   + ++     
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193

Query: 133  KEKKKRKKEKHSSTPNSSEFS 153
            K + +++KE         +FS
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFS 2214


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 10/116 (8%)

Query: 50  EDSDEENEELNK--LQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSS-------- 99
           ED DE++ +L+K  L A +E+  N+++  ++ +SK +    +   RS S SS        
Sbjct: 171 EDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR 230

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +   +S Q + +   +E+ + + SKS+      +     +K  +SS+ +S E +RK
Sbjct: 231 SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 11/105 (10%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           ED + E EE ++ + L + +++E+E++      +   L K     Y+  ++EE+ S +KK
Sbjct: 149 EDKESEGEEEDEDEDLSKYKLDEDEDE------DDADLSK-----YNLDASEEEDSNKKK 197

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
              + + K +   S+S          + R + +  S+ +S   SR
Sbjct: 198 SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSR 242



 Score = 36.2 bits (82), Expect = 0.012
 Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 2/107 (1%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           SS SS  S   +   ++ ++    + +      +E+S+ +    +   RS+  SS+    
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQ-SRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKE-KHSSTPNSS 150
           S        ++ +K+ +   S  G   K+  + R  E +H S+  SS
Sbjct: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319



 Score = 36.2 bits (82), Expect = 0.012
 Identities = 22/103 (21%), Positives = 43/103 (41%), Gaps = 3/103 (2%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S   S   +   ++ ++   +R      K +  S+        RKRSYSSSS+  + +
Sbjct: 225 SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN 284

Query: 106 KQKKQKYQKKE---KKKEKKSKSKKGKHHKKEKKKRKKEKHSS 145
           +++ +         KK+  +S+S + +H           + SS
Sbjct: 285 RKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327



 Score = 34.7 bits (78), Expect = 0.034
 Identities = 21/104 (20%), Positives = 42/104 (40%), Gaps = 8/104 (7%)

Query: 46  STSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS 105
           S S   S   ++  ++  + +  R    + +   +S       +KR  S SSSS E +  
Sbjct: 227 SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286

Query: 106 KQKKQKYQKKEKKK--------EKKSKSKKGKHHKKEKKKRKKE 141
           + + +     ++KK        E++ +S  G  H   +   KK+
Sbjct: 287 RSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 31/146 (21%), Positives = 57/146 (39%), Gaps = 5/146 (3%)

Query: 12  RAGCKKCGYPGHLTFECRN-FLRVDPKRDIVLDVSSTSSEDSDEENEELN-KLQALQEKR 69
           R+ C  C  P +   E R  +     +R+   +V     E+SD E +E   K +  + K 
Sbjct: 82  RSECNMCNTPKYAKLEERTGYGGGFNERE---NVEYIEREESDGEYDEFGRKKKKYRGKA 138

Query: 70  INEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK 129
           +      K+ + KE    ++      S    +ED  +      +      E++  +KK  
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS 198

Query: 130 HHKKEKKKRKKEKHSSTPNSSEFSRK 155
           + +   K R     SS+ +SS  S +
Sbjct: 199 NRRSRSKSRSSHSRSSSRSSSPSSSR 224


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 10/116 (8%)

Query: 50  EDSDEENEELNK--LQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSS-------- 99
           ED DE++ +L+K  L A +E+  N+++  ++ +SK +    +   RS S SS        
Sbjct: 171 EDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR 230

Query: 100 TEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
           +   +S Q + +   +E+ + + SKS+      +     +K  +SS+ +S E +RK
Sbjct: 231 SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 11/105 (10%)

Query: 50  EDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKK 109
           ED + E EE ++ + L + +++E+E++      +   L K     Y+  ++EE+ S +KK
Sbjct: 149 EDKESEGEEEDEDEDLSKYKLDEDEDE------DDADLSK-----YNLDASEEEDSNKKK 197

Query: 110 QKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSR 154
              + + K +   S+S          + R + +  S+ +S   SR
Sbjct: 198 SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSR 242



 Score = 33.5 bits (75), Expect = 0.075
 Identities = 19/107 (17%), Positives = 42/107 (39%), Gaps = 1/107 (0%)

Query: 45  SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDT 104
           SS SS  S   +   ++ ++    + +      +E+S+ +    +   RS+  SS+    
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQ-SRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272

Query: 105 SKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
           S        ++ +K+ +   S  G   K+  + R  E      N+ +
Sbjct: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQVIGENTKQ 319



 Score = 32.0 bits (71), Expect = 0.22
 Identities = 31/146 (21%), Positives = 57/146 (39%), Gaps = 5/146 (3%)

Query: 12  RAGCKKCGYPGHLTFECRN-FLRVDPKRDIVLDVSSTSSEDSDEENEELN-KLQALQEKR 69
           R+ C  C  P +   E R  +     +R+   +V     E+SD E +E   K +  + K 
Sbjct: 82  RSECNMCNTPKYAKLEERTGYGGGFNERE---NVEYIEREESDGEYDEFGRKKKKYRGKA 138

Query: 70  INEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGK 129
           +      K+ + KE    ++      S    +ED  +      +      E++  +KK  
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS 198

Query: 130 HHKKEKKKRKKEKHSSTPNSSEFSRK 155
           + +   K R     SS+ +SS  S +
Sbjct: 199 NRRSRSKSRSSHSRSSSRSSSPSSSR 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.300    0.118    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,810,682
Number of Sequences: 37866
Number of extensions: 372344
Number of successful extensions: 35312
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1653
Number of HSP's successfully gapped in prelim test: 782
Number of HSP's that attempted gapping in prelim test: 5033
Number of HSP's gapped (non-prelim): 15380
length of query: 155
length of database: 18,247,518
effective HSP length: 93
effective length of query: 62
effective length of database: 14,725,980
effective search space: 913010760
effective search space used: 913010760
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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