Guide to the Human Genome
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Search of human proteins with 27734871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734871 regulatory factor X, 6 [Homo sapiens]
         (928 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734871 regulatory factor X, 6 [Homo sapiens]                    1886   0.0  
gi|47132527 regulatory factor X4 isoform c [Homo sapiens]             433   e-121
gi|15011898 regulatory factor X4 isoform b [Homo sapiens]             427   e-119
gi|19743886 regulatory factor X4 isoform a [Homo sapiens]             332   1e-90
gi|19743879 regulatory factor X2 isoform b [Homo sapiens]             249   6e-66
gi|19743881 regulatory factor X2 isoform a [Homo sapiens]             247   3e-65
gi|4506495 regulatory factor X3 isoform a [Homo sapiens]              247   3e-65
gi|19743884 regulatory factor X3 isoform b [Homo sapiens]             247   3e-65
gi|238859557 regulatory factor X1 [Homo sapiens]                      242   1e-63
gi|224586784 hypothetical protein LOC731220 [Homo sapiens]            104   4e-22
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]    54   7e-07
gi|71040090 regulatory factor X, 5 [Homo sapiens]                      52   2e-06
gi|4557843 regulatory factor X, 5 [Homo sapiens]                       52   2e-06
gi|38373671 SEC24-related protein C [Homo sapiens]                     41   0.006
gi|38373669 SEC24-related protein C [Homo sapiens]                     41   0.006
gi|171543895 ataxin 2 [Homo sapiens]                                   37   0.11 
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    36   0.19 
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    36   0.19 
gi|47132519 Ras association and pleckstrin homology domains 1 is...    36   0.19 
gi|212276104 leucine rich repeat (in FLII) interacting protein 1...    35   0.32 
gi|212276096 leucine rich repeat (in FLII) interacting protein 1...    35   0.32 
gi|212276070 leucine rich repeat (in FLII) interacting protein 1...    35   0.32 
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              35   0.42 
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]     34   0.72 
gi|21361116 versican isoform 1 [Homo sapiens]                          34   0.72 
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]     34   0.72 
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]     34   0.72 
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]     34   0.72 
gi|4503249 DEK oncogene isoform 1 [Homo sapiens]                       34   0.72 
gi|28558973 mediator complex subunit 14 [Homo sapiens]                 34   0.72 

>gi|27734871 regulatory factor X, 6 [Homo sapiens]
          Length = 928

 Score = 1886 bits (4885), Expect = 0.0
 Identities = 928/928 (100%), Positives = 928/928 (100%)

Query: 1   MAKVPKLEDTFLQAQPAPQLSPGIQEDCCVQLLGKGLLVYPEETVYLAAEGQPGGEQGGG 60
           MAKVPKLEDTFLQAQPAPQLSPGIQEDCCVQLLGKGLLVYPEETVYLAAEGQPGGEQGGG
Sbjct: 1   MAKVPKLEDTFLQAQPAPQLSPGIQEDCCVQLLGKGLLVYPEETVYLAAEGQPGGEQGGG 60

Query: 61  EKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKDKKKQ 120
           EKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKDKKKQ
Sbjct: 61  EKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKDKKKQ 120

Query: 121 TQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTR 180
           TQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTR
Sbjct: 121 TQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTR 180

Query: 181 RLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTL 240
           RLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTL
Sbjct: 181 RLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTL 240

Query: 241 LPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPD 300
           LPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPD
Sbjct: 241 LPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPD 300

Query: 301 HLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSS 360
           HLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSS
Sbjct: 301 HLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSS 360

Query: 361 LENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNS 420
           LENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNS
Sbjct: 361 LENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNS 420

Query: 421 IGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKT 480
           IGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKT
Sbjct: 421 IGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKT 480

Query: 481 SKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQF 540
           SKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQF
Sbjct: 481 SKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQF 540

Query: 541 NNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYL 600
           NNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYL
Sbjct: 541 NNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYL 600

Query: 601 PLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGP 660
           PLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGP
Sbjct: 601 PLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGP 660

Query: 661 MAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYPH 720
           MAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYPH
Sbjct: 661 MAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYPH 720

Query: 721 HTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFL 780
           HTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFL
Sbjct: 721 HTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFL 780

Query: 781 SNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDP 840
           SNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDP
Sbjct: 781 SNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDP 840

Query: 841 LNILDDSGRKQTSSFYTDTSSPVACRTPVLASSLQTPIPSSSSQCMYGTSNQYPAQETLD 900
           LNILDDSGRKQTSSFYTDTSSPVACRTPVLASSLQTPIPSSSSQCMYGTSNQYPAQETLD
Sbjct: 841 LNILDDSGRKQTSSFYTDTSSPVACRTPVLASSLQTPIPSSSSQCMYGTSNQYPAQETLD 900

Query: 901 SHGTSSREMVSSLPPINTVFMGTAAGGT 928
           SHGTSSREMVSSLPPINTVFMGTAAGGT
Sbjct: 901 SHGTSSREMVSSLPPINTVFMGTAAGGT 928


>gi|47132527 regulatory factor X4 isoform c [Homo sapiens]
          Length = 735

 Score =  433 bits (1114), Expect = e-121
 Identities = 249/603 (41%), Positives = 334/603 (55%), Gaps = 34/603 (5%)

Query: 117 KKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPL 176
           K   T  TLQWLEENY + EGVC+PR  LY HYLDFC K   +P  AA+FGK IRQ+FP 
Sbjct: 54  KPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQ 113

Query: 177 LTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSK 236
           LTTRRLGTRG SKYHYYGI +KESS YY  +YS KG    S +  K     T  YS  SK
Sbjct: 114 LTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSK 173

Query: 237 TGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQ 296
            GTLLPEFP+ + L     + ++KV T IMMY+THCQ ILD  I  NF+E+Q FLLHFWQ
Sbjct: 174 LGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQ 233

Query: 297 GMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQW 356
           GMP H+LP+L +  +++I  VCDSILYK ++ VL+P  +Q +P+SL   IR FAK  ++W
Sbjct: 234 GMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEW 293

Query: 357 VVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERV 416
           +  +L +LPE L + K  + RRF   L+RQTS  HL Q +R  +    +   M+ D   V
Sbjct: 294 LKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNV 353

Query: 417 DLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQR 476
           DLNSI  Q L T+  S D    + T+     ++QE   LL++ + +E++IEWLDT+V++ 
Sbjct: 354 DLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVDRC 408

Query: 477 VIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAM 536
           V+K + +   SLKK AQ FLL WS FG RV+ ++TL++A SFGSFHLI ++ D+Y+L  +
Sbjct: 409 VVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLL 468

Query: 537 ETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVE 596
           E+    ++  EL   +       + S A           A      + S    K+ + VE
Sbjct: 469 ESLHCQERANELMRAM-----KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVE 523

Query: 597 TTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVI 656
              +P PSS            P+     +  TG M   Q     +T  ++ A  S     
Sbjct: 524 ---VPPPSSPVSN--------PSPEYTGLSTTGAM---QSYTWSLTYTVTTAAGSPAENS 569

Query: 657 NQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSG 716
            Q P              PS   T+  P+Y   P      Y+ S NY +     PH    
Sbjct: 570 QQLPCMRN-------THVPSSSVTHRIPVY---PHREEHGYTGSYNYGSYGNQHPHPMQS 619

Query: 717 LYP 719
            YP
Sbjct: 620 QYP 622


>gi|15011898 regulatory factor X4 isoform b [Homo sapiens]
          Length = 563

 Score =  427 bits (1098), Expect = e-119
 Identities = 214/436 (49%), Positives = 285/436 (65%), Gaps = 5/436 (1%)

Query: 117 KKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPL 176
           K   T  TLQWLEENY + EGVC+PR  LY HYLDFC K   +P  AA+FGK IRQ+FP 
Sbjct: 63  KPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQ 122

Query: 177 LTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSK 236
           LTTRRLGTRG SKYHYYGI +KESS YY  +YS KG    S +  K     T  YS  SK
Sbjct: 123 LTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSK 182

Query: 237 TGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQ 296
            GTLLPEFP+ + L     + ++KV T IMMY+THCQ ILD  I  NF+E+Q FLLHFWQ
Sbjct: 183 LGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQ 242

Query: 297 GMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQW 356
           GMP H+LP+L +  +++I  VCDSILYK ++ VL+P  +Q +P+SL   IR FAK  ++W
Sbjct: 243 GMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEW 302

Query: 357 VVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERV 416
           +  +L +LPE L + K  + RRF   L+RQTS  HL Q +R  +    +   M+ D   V
Sbjct: 303 LKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNV 362

Query: 417 DLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQR 476
           DLNSI  Q L T+  S D    + T+     ++QE   LL++ + +E++IEWLDT+V++ 
Sbjct: 363 DLNSITKQTLYTMEDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVDRC 417

Query: 477 VIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAM 536
           V+K + +   SLKK AQ FLL WS FG RV+ ++TL++A SFGSFHLI ++ D+Y+L  +
Sbjct: 418 VVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLL 477

Query: 537 ETQFNNDKEQELQNLL 552
           E+    ++  EL   +
Sbjct: 478 ESLHCQERANELMRAM 493


>gi|19743886 regulatory factor X4 isoform a [Homo sapiens]
          Length = 641

 Score =  332 bits (851), Expect = 1e-90
 Identities = 200/530 (37%), Positives = 280/530 (52%), Gaps = 34/530 (6%)

Query: 190 YHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQH 249
           YHYYGI +KESS YY  +YS KG    S +  K     T  YS  SK GTLLPEFP+ + 
Sbjct: 33  YHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKD 92

Query: 250 LVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENP 309
           L     + ++KV T IMMY+THCQ ILD  I  NF+E+Q FLLHFWQGMP H+LP+L + 
Sbjct: 93  LNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSS 152

Query: 310 VIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALT 369
            +++I  VCDSILYK ++ VL+P  +Q +P+SL   IR FAK  ++W+  +L +LPE L 
Sbjct: 153 TVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLR 212

Query: 370 DKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTI 429
           + K  + RRF   L+RQTS  HL Q +R  +    +   M+ D   VDLNSI  Q L T+
Sbjct: 213 NIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTM 272

Query: 430 SGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLK 489
             S D    + T+     ++QE   LL++ + +E++IEWLDT+V++ V+K + +   SLK
Sbjct: 273 EDSRDEHRKLITQ-----LYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLK 327

Query: 490 KRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQ 549
           K AQ FLL WS FG RV+ ++TL++A SFGSFHLI ++ D+Y+L  +E+    ++  EL 
Sbjct: 328 KVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELM 387

Query: 550 NLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGG 609
             +       + S A           A      + S    K+ + VE   +P PSS    
Sbjct: 388 RAM-----KGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVE---VPPPSSPVSN 439

Query: 610 LGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVG 669
                   P+     +  TG M   Q     +T  ++ A  S      Q P         
Sbjct: 440 --------PSPEYTGLSTTGAM---QSYTWSLTYTVTTAAGSPAENSQQLPCMRN----- 483

Query: 670 PVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYP 719
                PS   T+  P+Y   P      Y+ S NY +     PH     YP
Sbjct: 484 --THVPSSSVTHRIPVY---PHREEHGYTGSYNYGSYGNQHPHPMQSQYP 528


>gi|19743879 regulatory factor X2 isoform b [Homo sapiens]
          Length = 698

 Score =  249 bits (637), Expect = 6e-66
 Identities = 158/472 (33%), Positives = 238/472 (50%), Gaps = 64/472 (13%)

Query: 119 KQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLT 178
           + +  TLQWL +NY   EGV LPR  LY HYL  C++ KL+P  AA+FGK IR  F  L 
Sbjct: 169 RSSPATLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLR 228

Query: 179 TRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLT----------RFSGSK----LKNE 224
           TRRLGTRG+SKYHYYGI +K  S         + +           R+  ++    L + 
Sbjct: 229 TRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDS 288

Query: 225 GGFTRKYSLSSKT--------------GTLLPEFPSAQ--HLVYQGCISKDKVDTLIMMY 268
           G  +  +S   +T                + PEFP+      + Q  ++   V  L ++Y
Sbjct: 289 GSHSGLHSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVY 348

Query: 269 KTHCQCILDNAINGNFEEIQHFLLHFWQGMP-----------------------DHLLPL 305
           + HC+  +D  +N  F  I+   L FW                           D L+ L
Sbjct: 349 RRHCEATVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISL 408

Query: 306 LENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLP 365
            +   I+     CD ILY+ L ++LIP  ++ +P +L   IRNFAK+ E W+ +++ + P
Sbjct: 409 CQCDPILRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFP 468

Query: 366 EALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQA 425
           + +   K+ +V  F  +L+R TS  HLAQ AR  L +   +N M+SD+ RVD  ++  QA
Sbjct: 469 QQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQA 528

Query: 426 LLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNG 485
               S     E  +    +     Q+ K  L++ ++++ +  WLD+VV Q  +       
Sbjct: 529 ----SWVCQCEESVVQRLE-----QDFKLTLQQQSSLDQWASWLDSVVTQ--VLKQHAGS 577

Query: 486 RSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAME 537
            S  K A+ FLLKWSF+ + V+ +LTL +A+SFGSFHLIR+L DEY+   +E
Sbjct: 578 PSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVE 629


>gi|19743881 regulatory factor X2 isoform a [Homo sapiens]
          Length = 723

 Score =  247 bits (631), Expect = 3e-65
 Identities = 157/466 (33%), Positives = 235/466 (50%), Gaps = 64/466 (13%)

Query: 125 LQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGT 184
           LQWL +NY   EGV LPR  LY HYL  C++ KL+P  AA+FGK IR  F  L TRRLGT
Sbjct: 200 LQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLDPVNAASFGKLIRSVFMGLRTRRLGT 259

Query: 185 RGHSKYHYYGIGIKESSAYYHSVYSGKGLT----------RFSGSK----LKNEGGFTRK 230
           RG+SKYHYYGI +K  S         + +           R+  ++    L + G  +  
Sbjct: 260 RGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPMHQKPRYRPAQKTDSLGDSGSHSGL 319

Query: 231 YSLSSKT--------------GTLLPEFPSAQ--HLVYQGCISKDKVDTLIMMYKTHCQC 274
           +S   +T                + PEFP+      + Q  ++   V  L ++Y+ HC+ 
Sbjct: 320 HSTPEQTMAVQSQHHQQYIDVSHVFPEFPAPDLGSFLLQDGVTLHDVKALQLVYRRHCEA 379

Query: 275 ILDNAINGNFEEIQHFLLHFWQGMP-----------------------DHLLPLLENPVI 311
            +D  +N  F  I+   L FW                           D L+ L +   I
Sbjct: 380 TVDVVMNLQFHYIEKLWLSFWNSKASSSDGPTSLPASDEDPEGAVLPKDKLISLCQCDPI 439

Query: 312 IDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDK 371
           +     CD ILY+ L ++LIP  ++ +P +L   IRNFAK+ E W+ +++ + P+ +   
Sbjct: 440 LRWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMSDFPQQVIQT 499

Query: 372 KIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISG 431
           K+ +V  F  +L+R TS  HLAQ AR  L +   +N M+SD+ RVD  ++  QA    S 
Sbjct: 500 KVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQA----SW 555

Query: 432 STDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKR 491
               E  +    +     Q+ K  L++ ++++ +  WLD+VV Q  +        S  K 
Sbjct: 556 VCQCEESVVQRLE-----QDFKLTLQQQSSLDQWASWLDSVVTQ--VLKQHAGSPSFPKA 608

Query: 492 AQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAME 537
           A+ FLLKWSF+ + V+ +LTL +A+SFGSFHLIR+L DEY+   +E
Sbjct: 609 ARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVE 654


>gi|4506495 regulatory factor X3 isoform a [Homo sapiens]
          Length = 707

 Score =  247 bits (631), Expect = 3e-65
 Identities = 158/468 (33%), Positives = 231/468 (49%), Gaps = 67/468 (14%)

Query: 125 LQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGT 184
           LQWL +NY   EGV LPR  LY HYL  C++ KL+P  AA+FGK IR  F  L TRRLGT
Sbjct: 184 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT 243

Query: 185 RGHSKYHYYGIGIKESSAY----------------------YHSVYSGKGLTR-FSGSKL 221
           RG+SKYHYYGI +K  S                        Y  +    G+   F+GS  
Sbjct: 244 RGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQ 303

Query: 222 KNEGGFTRKYSLSSK-------TGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQC 274
           +      +     S+           LPEF   +        + + + +L  +Y+ HC+ 
Sbjct: 304 QTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEA 363

Query: 275 ILDNAINGNFEEIQHFLLHFWQGMPD------------------------HLLPLLENPV 310
           ILD  +N  F  I+     FW+  P                          L+ L ++  
Sbjct: 364 ILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHES 423

Query: 311 IIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTD 370
           I+   C CD  +Y+ L ++LIP  ++ +P +L   IRNFAK+ E W+ +++ N+P+ +  
Sbjct: 424 ILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQ 483

Query: 371 KKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTIS 430
            K+  V  F  +L+R TS  HLAQ AR  L +   +N M+SD+ RVD  ++  QA     
Sbjct: 484 TKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ 543

Query: 431 GSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGR-SLK 489
              +    + T         + K  L++ +T+E +  WLD V+ Q +       GR S  
Sbjct: 544 CDDNMVQRLET---------DFKMTLQQQSTLEQWAAWLDNVMMQAL---KPYEGRPSFP 591

Query: 490 KRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAME 537
           K A+ FLLKWSF+ + V+ +LTL +A+SFGSFHLIR+L DEY+   +E
Sbjct: 592 KAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVE 639


>gi|19743884 regulatory factor X3 isoform b [Homo sapiens]
          Length = 749

 Score =  247 bits (631), Expect = 3e-65
 Identities = 158/468 (33%), Positives = 231/468 (49%), Gaps = 67/468 (14%)

Query: 125 LQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGT 184
           LQWL +NY   EGV LPR  LY HYL  C++ KL+P  AA+FGK IR  F  L TRRLGT
Sbjct: 184 LQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGT 243

Query: 185 RGHSKYHYYGIGIKESSAY----------------------YHSVYSGKGLTR-FSGSKL 221
           RG+SKYHYYGI +K  S                        Y  +    G+   F+GS  
Sbjct: 244 RGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQ 303

Query: 222 KNEGGFTRKYSLSSK-------TGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQC 274
           +      +     S+           LPEF   +        + + + +L  +Y+ HC+ 
Sbjct: 304 QTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEA 363

Query: 275 ILDNAINGNFEEIQHFLLHFWQGMPD------------------------HLLPLLENPV 310
           ILD  +N  F  I+     FW+  P                          L+ L ++  
Sbjct: 364 ILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITESSNLSEIESRLPKAKLITLCKHES 423

Query: 311 IIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTD 370
           I+   C CD  +Y+ L ++LIP  ++ +P +L   IRNFAK+ E W+ +++ N+P+ +  
Sbjct: 424 ILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQ 483

Query: 371 KKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTIS 430
            K+  V  F  +L+R TS  HLAQ AR  L +   +N M+SD+ RVD  ++  QA     
Sbjct: 484 TKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQ 543

Query: 431 GSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGR-SLK 489
              +    + T         + K  L++ +T+E +  WLD V+ Q +       GR S  
Sbjct: 544 CDDNMVQRLET---------DFKMTLQQQSTLEQWAAWLDNVMMQAL---KPYEGRPSFP 591

Query: 490 KRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAME 537
           K A+ FLLKWSF+ + V+ +LTL +A+SFGSFHLIR+L DEY+   +E
Sbjct: 592 KAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVE 639


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score =  242 bits (618), Expect = 1e-63
 Identities = 159/468 (33%), Positives = 236/468 (50%), Gaps = 68/468 (14%)

Query: 124 TLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLG 183
           T+QWL +NY   EGV LPR  LY HYL  C+++KLEP  AA+FGK IR  F  L TRRLG
Sbjct: 438 TVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLG 497

Query: 184 TRGHSKYHYYGIGIKESSA-------YYHSVYSGKGLTRFSGSK-LKNEGGFTRKYSLSS 235
           TRG+SKYHYYG+ IK SS          H    G+  ++    K ++   G T   ++  
Sbjct: 498 TRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQ 557

Query: 236 KTGTLLPEFPSAQHLVYQGCISKDK-----------------------VDTLIMMYKTHC 272
           +  T L +  SAQ   YQ  +   +                       +    ++Y+ HC
Sbjct: 558 QPSTGLSDI-SAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQVLYREHC 616

Query: 273 QCILDNAINGNFEEIQHFLLHFW--------------------QGMPDHLLPLLEN-PVI 311
           + I+D  +N  F  ++     FW                    + +P  +L LL     +
Sbjct: 617 EAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLLSKFEPV 676

Query: 312 IDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDK 371
           +     CD++LY+ L ++LIP  ++ +P +L   IRNFAK+ E W+  ++ N+PE +   
Sbjct: 677 LQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRV 736

Query: 372 KIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISG 431
           K+     F  +L+R TS  HLAQ AR  L +   +N M+SD+ RVD  ++  QA      
Sbjct: 737 KVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQA------ 790

Query: 432 STDTESGIYTEHDSIT--VFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLK 489
                S +    D +   + Q+ K  L++  ++E +  WLD VV Q  +    Q      
Sbjct: 791 -----SWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQ--VLKPYQGSAGFP 843

Query: 490 KRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAME 537
           K A+ FLLKWSF+ + V+ +LTL +A+SFGSFHLIR+L DEY+   +E
Sbjct: 844 KAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIE 891


>gi|224586784 hypothetical protein LOC731220 [Homo sapiens]
          Length = 473

 Score =  104 bits (259), Expect = 4e-22
 Identities = 72/281 (25%), Positives = 141/281 (50%), Gaps = 12/281 (4%)

Query: 268 YKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLT 327
           Y  +C+ IL N        ++  L  FW+ +    + L+  P +  +F   D  LYK + 
Sbjct: 69  YCNYCRDILRN--------VEDLLTSFWKSLQQDTVMLMSLPDVCQLFKCYDVQLYKGIE 120

Query: 328 DVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQT 387
           DVL+   ++++    L  ++ F+K ++ W++++LE +P  L   K+  V  FV  L+R+T
Sbjct: 121 DVLLHDFLEDVSIQYLKSVQLFSKKFKLWLLNALEGVPALLQISKLKEVTLFVKRLRRKT 180

Query: 388 SFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGIYTEHD-SI 446
              ++A+  R  L  +  V+ + SD++ + +N  G+ A    + ++D       E++  +
Sbjct: 181 YLSNMAKTMRMVLKSKRRVSVLKSDLQAI-INQ-GTLATSKKALASDRSGADELENNPEM 238

Query: 447 TVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARV 506
              + L  LL  +  +  F+  L + ++  V +TS+       K A  F L+W+     V
Sbjct: 239 KCLRNLISLLGTSTDLRVFLSCLSSHLQAFVFQTSRSK-EEFTKLAASFQLRWNLLLTAV 297

Query: 507 MHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQE 547
              +TL +  SFGS+HL  +LL EY++  +++    ++E+E
Sbjct: 298 SKAMTLCHRDSFGSWHLFHLLLLEYMIHILQSCLEEEEEEE 338


>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
          Length = 1460

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 28/89 (31%), Positives = 40/89 (44%)

Query: 107 KKTITQIVKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATF 166
           +K+    +   + Q      W+           LP+  +Y  Y  +C      P  AA F
Sbjct: 91  EKSDQNAMSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLGYHPLSAADF 150

Query: 167 GKTIRQKFPLLTTRRLGTRGHSKYHYYGI 195
           GK ++  FP +  RRLGTRG SKY Y G+
Sbjct: 151 GKIMKNVFPNMKARRLGTRGKSKYCYSGL 179


>gi|71040090 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 126 QWLEENYIVCEGVCLPRCILYAHYLDFCRKEKL-EPACAATFGKTIRQKFPLLTTRRLGT 184
           +W+  +       CLP+  +Y  Y  +C       P   A FGK IR+ FP +  RRLG 
Sbjct: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153

Query: 185 RGHSKYHYYGI 195
           RG SKY Y GI
Sbjct: 154 RGQSKYCYSGI 164


>gi|4557843 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 126 QWLEENYIVCEGVCLPRCILYAHYLDFCRKEKL-EPACAATFGKTIRQKFPLLTTRRLGT 184
           +W+  +       CLP+  +Y  Y  +C       P   A FGK IR+ FP +  RRLG 
Sbjct: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153

Query: 185 RGHSKYHYYGI 195
           RG SKY Y GI
Sbjct: 154 RGQSKYCYSGI 164


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 44/164 (26%), Positives = 64/164 (39%), Gaps = 11/164 (6%)

Query: 602 LPSSQPGG--LGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQG 659
           LP SQP G  L P  +Q P       P T     +Q++G  ++  ++PA  S G  +  G
Sbjct: 104 LPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSG--LGFG 161

Query: 660 PMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYP 719
           P      + G   ++  +  +YP+   P L QA           QT  R+ P   S   P
Sbjct: 162 PPTSLASASGSFPNSGLY-GSYPQGQAPPLSQA-----QGHPGIQTPQRSAPSQASSFTP 215

Query: 720 HHTEHGRCMAWTEQQLSRDFFSGSCAGSP-YNSRPPSSYGPSLQ 762
             +   R  + T   L    F G     P + S PP +  P  Q
Sbjct: 216 PASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQ 259


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 44/164 (26%), Positives = 64/164 (39%), Gaps = 11/164 (6%)

Query: 602 LPSSQPGG--LGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQG 659
           LP SQP G  L P  +Q P       P T     +Q++G  ++  ++PA  S G  +  G
Sbjct: 104 LPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSG--LGFG 161

Query: 660 PMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYP 719
           P      + G   ++  +  +YP+   P L QA           QT  R+ P   S   P
Sbjct: 162 PPTSLASASGSFPNSGLY-GSYPQGQAPPLSQA-----QGHPGIQTPQRSAPSQASSFTP 215

Query: 720 HHTEHGRCMAWTEQQLSRDFFSGSCAGSP-YNSRPPSSYGPSLQ 762
             +   R  + T   L    F G     P + S PP +  P  Q
Sbjct: 216 PASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQ 259


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 19/177 (10%)

Query: 563  KAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPAGNT 622
            K  +    S  F    + GS+    A  N +    T  P PS+ P G   + H    G +
Sbjct: 1109 KLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQH----GGS 1164

Query: 623  DNMPLTGQMELSQIAG--HLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCST 680
               P   Q    Q A   HL +P        + S I    +A  PPS+ P  +  S  ++
Sbjct: 1165 HPAPSPVQHHQHQAAQALHLASP-------QQQSAIYHAGLAPTPPSMTPASNTQSPQNS 1217

Query: 681  YP---EPIYPALPQANHDFYSTSSNYQTVFRAQPHSTSGLYPHH-TEHGRCMAWTEQ 733
            +P   + ++   P      Y+   +   V   Q H  SG+ P H T H   M  T Q
Sbjct: 1218 FPAAQQTVFTIHPSHVQPAYTNPPHMAHV--PQAHVQSGMVPSHPTAHAPMMLMTTQ 1272


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 45/195 (23%), Positives = 68/195 (34%), Gaps = 23/195 (11%)

Query: 641 MTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTS 700
           M+ P  P     G++ + GP  G  PS GP+L         P P     P + H     S
Sbjct: 1   MSTPTDP-----GAMPHPGPSPGPGPSPGPILG--------PSPGPGPSPGSVHSMMGPS 47

Query: 701 SNYQTVFRAQPHSTSGLYPH---HTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPP-SS 756
               +V    P   S  +P    H  H       ++ +  D   GS  G+    RPP   
Sbjct: 48  PGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGT--GMRPPHPG 105

Query: 757 YGPSLQAQDSHNMQFL--NTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRL 814
            GP     D H+  ++  +        +  +    G   PP  P    G+ I  P   + 
Sbjct: 106 MGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALI--PGDPQA 163

Query: 815 GSMVNQHVSVISSIR 829
            S  N+  S  S ++
Sbjct: 164 MSQPNRGPSPFSPVQ 178


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 45/195 (23%), Positives = 68/195 (34%), Gaps = 23/195 (11%)

Query: 641 MTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQANHDFYSTS 700
           M+ P  P     G++ + GP  G  PS GP+L         P P     P + H     S
Sbjct: 1   MSTPTDP-----GAMPHPGPSPGPGPSPGPILG--------PSPGPGPSPGSVHSMMGPS 47

Query: 701 SNYQTVFRAQPHSTSGLYPH---HTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPP-SS 756
               +V    P   S  +P    H  H       ++ +  D   GS  G+    RPP   
Sbjct: 48  PGPPSVSHPMPTMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGT--GMRPPHPG 105

Query: 757 YGPSLQAQDSHNMQFL--NTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRL 814
            GP     D H+  ++  +        +  +    G   PP  P    G+ I  P   + 
Sbjct: 106 MGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALI--PGDPQA 163

Query: 815 GSMVNQHVSVISSIR 829
            S  N+  S  S ++
Sbjct: 164 MSQPNRGPSPFSPVQ 178


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 9/96 (9%)

Query: 601 PLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRG-----SV 655
           PLPS      G A   F   +T    +T     SQ +G L  PP  P M S+       V
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYST----ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703

Query: 656 INQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPALPQ 691
              G +   PP   P     +     P P  P+LPQ
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ 739


>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
           isoform 5 [Homo sapiens]
          Length = 752

 Score = 35.0 bits (79), Expect = 0.32
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 9/89 (10%)

Query: 42  EETVYLAAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAAD 101
           E+ +     G P G +G  ++   P       S +   N     +E D +  D + +A D
Sbjct: 455 EKPIKTEVPGSPAGTEGNCQEATGP-------STVDTQNEPLDMKEPDEEKSDQQGEALD 507

Query: 102 QYLSQKKTITQIVKDKKKQTQLTLQWLEE 130
              SQKKT  +  K+KKK++ + ++ L++
Sbjct: 508 S--SQKKTKNKKKKNKKKKSPVPVETLKD 534


>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
           isoform 3 [Homo sapiens]
          Length = 808

 Score = 35.0 bits (79), Expect = 0.32
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 9/89 (10%)

Query: 42  EETVYLAAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAAD 101
           E+ +     G P G +G  ++   P       S +   N     +E D +  D + +A D
Sbjct: 511 EKPIKTEVPGSPAGTEGNCQEATGP-------STVDTQNEPLDMKEPDEEKSDQQGEALD 563

Query: 102 QYLSQKKTITQIVKDKKKQTQLTLQWLEE 130
              SQKKT  +  K+KKK++ + ++ L++
Sbjct: 564 S--SQKKTKNKKKKNKKKKSPVPVETLKD 590


>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
           isoform 4 [Homo sapiens]
          Length = 784

 Score = 35.0 bits (79), Expect = 0.32
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 9/89 (10%)

Query: 42  EETVYLAAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAAD 101
           E+ +     G P G +G  ++   P       S +   N     +E D +  D + +A D
Sbjct: 487 EKPIKTEVPGSPAGTEGNCQEATGP-------STVDTQNEPLDMKEPDEEKSDQQGEALD 539

Query: 102 QYLSQKKTITQIVKDKKKQTQLTLQWLEE 130
              SQKKT  +  K+KKK++ + ++ L++
Sbjct: 540 S--SQKKTKNKKKKNKKKKSPVPVETLKD 566


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 11/88 (12%)

Query: 616  QFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQG-------PMAGRPPSV 668
            QFP   T N+P + +ME   +  HL+  P+S   AS+  ++++        PM+G  P+ 
Sbjct: 1892 QFPISTTINVPTSNEMETETL--HLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNH 1949

Query: 669  GPVLSAPSHCSTYPEPIYPALPQANHDF 696
            G  LS     ST    I   L    H F
Sbjct: 1950 G--LSENPSLSTSLRAITSTLADVKHTF 1975


>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
          Length = 813

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 38/171 (22%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 557 KNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQ 616
           + SD S+ ++  SP SC     + G +   +    ESH           +PG + PA+  
Sbjct: 498 EKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGN-------GLEPGEI-PAV-- 547

Query: 617 FPAGNTDNMPL----TGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVL 672
            P+G  ++  +     G+ + S+   H ++ P  PA +    V  Q P     P V  + 
Sbjct: 548 -PSGERNSFKVPSIAEGENKTSKSWRHPLSRP--PARSPMTLVKQQAPSDEELPEVLSIE 604

Query: 673 SAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHST--SGLYPHH 721
                  ++ +P+       + +F +      TV R +PH    + L P+H
Sbjct: 605 EEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYH 655


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 16/51 (31%), Positives = 28/51 (54%)

Query: 66   PELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKD 116
            PE P  ++ +++ +  N   EEE A+  D  T  + QY++ K  +T + KD
Sbjct: 1373 PEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKD 1423


>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
          Length = 835

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 38/171 (22%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 557 KNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQ 616
           + SD S+ ++  SP SC     + G +   +    ESH           +PG + PA+  
Sbjct: 520 EKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGN-------GLEPGEI-PAV-- 569

Query: 617 FPAGNTDNMPL----TGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVL 672
            P+G  ++  +     G+ + S+   H ++ P  PA +    V  Q P     P V  + 
Sbjct: 570 -PSGERNSFKVPSIAEGENKTSKSWRHPLSRP--PARSPMTLVKQQAPSDEELPEVLSIE 626

Query: 673 SAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHST--SGLYPHH 721
                  ++ +P+       + +F +      TV R +PH    + L P+H
Sbjct: 627 EEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYH 677


>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
          Length = 1047

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 38/171 (22%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 557 KNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQ 616
           + SD S+ ++  SP SC     + G +   +    ESH           +PG + PA+  
Sbjct: 498 EKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGN-------GLEPGEI-PAV-- 547

Query: 617 FPAGNTDNMPL----TGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVL 672
            P+G  ++  +     G+ + S+   H ++ P  PA +    V  Q P     P V  + 
Sbjct: 548 -PSGERNSFKVPSIAEGENKTSKSWRHPLSRP--PARSPMTLVKQQAPSDEELPEVLSIE 604

Query: 673 SAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHST--SGLYPHH 721
                  ++ +P+       + +F +      TV R +PH    + L P+H
Sbjct: 605 EEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYH 655


>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
          Length = 1056

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 38/171 (22%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 557 KNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQ 616
           + SD S+ ++  SP SC     + G +   +    ESH           +PG + PA+  
Sbjct: 498 EKSDPSELSWPKSPESCSSVAESNGVLTEGEESDVESHGN-------GLEPGEI-PAV-- 547

Query: 617 FPAGNTDNMPL----TGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVL 672
            P+G  ++  +     G+ + S+   H ++ P  PA +    V  Q P     P V  + 
Sbjct: 548 -PSGERNSFKVPSIAEGENKTSKSWRHPLSRP--PARSPMTLVKQQAPSDEELPEVLSIE 604

Query: 673 SAPSHCSTYPEPIYPALPQANHDFYSTSSNYQTVFRAQPHST--SGLYPHH 721
                  ++ +P+       + +F +      TV R +PH    + L P+H
Sbjct: 605 EEVEETESWAKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYH 655


>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
          Length = 375

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 16/79 (20%)

Query: 48  AAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQK 107
           AAEG+    Q   EK  +PE+PG  +          S EEED D+ + + +       +K
Sbjct: 7   AAEGEGTPTQPASEK--EPEMPGPREE---------SEEEEDEDDEEEEEEE-----KEK 50

Query: 108 KTITQIVKDKKKQTQLTLQ 126
             I +  ++KKK  +LT+Q
Sbjct: 51  SLIVEGKREKKKVERLTMQ 69


>gi|28558973 mediator complex subunit 14 [Homo sapiens]
          Length = 1454

 Score = 33.9 bits (76), Expect = 0.72
 Identities = 49/181 (27%), Positives = 69/181 (38%), Gaps = 20/181 (11%)

Query: 742  GSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGY 801
            G+    P  S PP+SY  ++    S     ++T S     N  AAS     L   SP  +
Sbjct: 1014 GTSGAYPLTS-PPTSYHSTVNQSPS----MMHTQS---PGNLHAASSPSGALRAPSPASF 1065

Query: 802  YGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDPLNILDDSGRKQTSSFYTDTSS 861
              +    P SH  G  +    S  S   +L P S    P  ++  SGR          S 
Sbjct: 1066 VPTPP--PSSH--GISIGPGASFASPHGTLDPSS----PYTMVSPSGRAGNWPGSPQVSG 1117

Query: 862  PV-ACRTPVLAS---SLQTPIPSSSSQCMYGTSNQYPAQETLDSHGTSSREMVSSLPPIN 917
            P  A R P ++    SL +P+P +S     GTS+Q              R   +S+P I 
Sbjct: 1118 PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTIL 1177

Query: 918  T 918
            T
Sbjct: 1178 T 1178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,178,610
Number of Sequences: 37866
Number of extensions: 1919765
Number of successful extensions: 6768
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 6635
Number of HSP's gapped (non-prelim): 206
length of query: 928
length of database: 18,247,518
effective HSP length: 112
effective length of query: 816
effective length of database: 14,006,526
effective search space: 11429325216
effective search space used: 11429325216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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