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Search of human proteins with 27734799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27734799 REST corepressor 2 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27734799 REST corepressor 2 [Homo sapiens] 1072 0.0
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 558 e-159
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 546 e-155
gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 468 e-132
gi|7661892 REST corepressor 1 [Homo sapiens] 427 e-119
gi|209977082 REST corepressor 3 isoform b [Homo sapiens] 385 e-107
gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens] 214 2e-55
gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens] 214 2e-55
gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi... 214 2e-55
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 103 5e-22
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 100 6e-21
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 86 1e-16
gi|153792074 proline rich 12 [Homo sapiens] 66 7e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 66 9e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 64 3e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 64 3e-10
gi|160707881 formin 2 [Homo sapiens] 64 3e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 3e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 3e-10
gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens] 64 3e-10
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 63 6e-10
gi|150417989 cyclin K isoform 1 [Homo sapiens] 63 6e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 7e-10
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 61 2e-09
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 61 2e-09
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 60 4e-09
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 60 6e-09
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 60 6e-09
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 60 6e-09
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 60 6e-09
>gi|27734799 REST corepressor 2 [Homo sapiens]
Length = 523
Score = 1072 bits (2773), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MPSVMEKPSAGSGILSRSRAKTVPNGGQPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECK 60
MPSVMEKPSAGSGILSRSRAKTVPNGGQPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECK
Sbjct: 1 MPSVMEKPSAGSGILSRSRAKTVPNGGQPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECK 60
Query: 61 PESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEK 120
PESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEK
Sbjct: 61 PESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEK 120
Query: 121 SLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTR 180
SLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTR
Sbjct: 121 SLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTR 180
Query: 181 SRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGK 240
SRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGK
Sbjct: 181 SRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGK 240
Query: 241 KEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQS 300
KEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQS
Sbjct: 241 KEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQS 300
Query: 301 MKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGN 360
MKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGN
Sbjct: 301 MKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGN 360
Query: 361 KTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEV 420
KTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEV
Sbjct: 361 KTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEV 420
Query: 421 QITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL 480
QITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL
Sbjct: 421 QITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL 480
Query: 481 APNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
APNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAPSL
Sbjct: 481 APNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 558 bits (1439), Expect = e-159
Identities = 311/552 (56%), Positives = 387/552 (70%), Gaps = 48/552 (8%)
Query: 1 MPSVMEKPSAGSGILSRSRAK---------------TVPNGGQPHSEDDSS-EEEHSHDS 44
MP +MEK G +L ++R+ + NGG +SE +S + HD
Sbjct: 1 MPGMMEK---GPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDV 57
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
+RVG YQA IPE P + +Y++K+ GMLVWSP H + DAKLD+YIA+AKEKHGYN+
Sbjct: 58 GMRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV 116
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 117 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 176
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPA 220
I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P
Sbjct: 177 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KK 235
Query: 221 DPKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDL 279
+ K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+
Sbjct: 236 EAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNA 295
Query: 280 ANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLL 339
AN LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLL
Sbjct: 296 ANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLL 355
Query: 340 AVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---A 396
AVQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ A
Sbjct: 356 AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDA 415
Query: 397 PVPMEEARRGAPLPA-PALEEDDEVQITSVSTSVPRSVPPAPPPP---PPPT----SLSQ 448
EE + + +P+ + +E++E Q + PR++ P+PP P P PT +L+Q
Sbjct: 416 STLGEETKSASNVPSGKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTPTPTAPIATLNQ 471
Query: 449 PPPLLRPPLPTAPTLLRQPPPL-QQGRFLQPRLAPNQPPPPLIRPALA-APRHSARP--- 503
PPPLLRP LP AP L RQPPPL QQ RF+QPR NQPPPPLIRPA + PR + RP
Sbjct: 472 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 531
Query: 504 --GPQPPPTLIG 513
G Q PP+LIG
Sbjct: 532 TVGGQQPPSLIG 543
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 546 bits (1408), Expect = e-155
Identities = 295/491 (60%), Positives = 362/491 (73%), Gaps = 29/491 (5%)
Query: 46 IRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIE 105
+RVG YQA IPE P + +Y++K+ GMLVWSP H + DAKLD+YIA+AKEKHGYN+E
Sbjct: 1 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 59
Query: 106 QALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKL 165
QALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 60 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 119
Query: 166 IPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPAD 221
I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P +
Sbjct: 120 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KKE 178
Query: 222 PKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLA 280
K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+ A
Sbjct: 179 AKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAA 238
Query: 281 NLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLA 340
N LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLLA
Sbjct: 239 NTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLA 298
Query: 341 VQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---AP 397
VQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ A
Sbjct: 299 VQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDAS 358
Query: 398 VPMEEARRGAPLPA-PALEEDDEVQITSVSTSVPRSVPPAPPPP---PPPT----SLSQP 449
EE + + +P+ + +E++E Q + PR++ P+PP P P PT +L+QP
Sbjct: 359 TLGEETKSASNVPSGKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTPTPTAPIATLNQP 414
Query: 450 PPLLRPPLPTAPTLLRQPPPL-QQGRFLQPRLAPNQPPPPLIRPALA-APRHSARP---- 503
PPLLRP LP AP L RQPPPL QQ RF+QPR NQPPPPLIRPA + PR + RP
Sbjct: 415 PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 474
Query: 504 -GPQPPPTLIG 513
G Q PP+LIG
Sbjct: 475 VGGQQPPSLIG 485
>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
Length = 449
Score = 468 bits (1203), Expect = e-132
Identities = 253/445 (56%), Positives = 319/445 (71%), Gaps = 30/445 (6%)
Query: 1 MPSVMEKPSAGSGILSRSRAK---------------TVPNGGQPHSEDDSS-EEEHSHDS 44
MP +MEK G +L ++R+ + NGG +SE +S + HD
Sbjct: 1 MPGMMEK---GPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDV 57
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
+RVG YQA IPE P + +Y++K+ GMLVWSP H + DAKLD+YIA+AKEKHGYN+
Sbjct: 58 GMRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV 116
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 117 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 176
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPA 220
I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P
Sbjct: 177 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KK 235
Query: 221 DPKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDL 279
+ K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+
Sbjct: 236 EAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNA 295
Query: 280 ANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLL 339
AN LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLL
Sbjct: 296 ANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLL 355
Query: 340 AVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---A 396
AVQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ A
Sbjct: 356 AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDA 415
Query: 397 PVPMEEARRGAPLPA-PALEEDDEV 420
EE + + +P+ + +E++EV
Sbjct: 416 STLGEETKSASNVPSGKSTDEEEEV 440
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 427 bits (1098), Expect = e-119
Identities = 231/421 (54%), Positives = 290/421 (68%), Gaps = 22/421 (5%)
Query: 16 SRSRAKTVPNGG------QPHSEDDSSEEEHSHDSMIRVGTNYQAVIPECKPESPARYSN 69
++S A PNG + S SS+EEH M RVG YQAV+P+ P AR S
Sbjct: 67 NKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGM-RVGPQYQAVVPDFDPAKLARRSQ 125
Query: 70 -KELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIEQALGMLLWHKHDVEKSLADLANF 128
++ GMLVWSPN +S+AKLD+YIA+AKEKHGYN+EQALGML WHKH++EKSLADL NF
Sbjct: 126 ERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEKSLADLPNF 185
Query: 129 TPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDR 188
TPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK I SLVK+YYSWKKTR++TSVMDR
Sbjct: 186 TPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDR 245
Query: 189 QARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQY 248
AR+ R+ +E DELEE G + D +E P KKE +Q
Sbjct: 246 HARK-QKREREESEDELEEANG--NNPIDIEVDQNKESKKEVPPTETVPQVKKEKHSTQA 302
Query: 249 RHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSL 308
++ R +R+PPKGM+LS E + AVS + A LR LD +L+S+KRQ+Q++KQTNS+L
Sbjct: 303 KN---RAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNSAL 359
Query: 309 RQALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKT 368
++ L+GGI+P R PE K N+RWTT+EQLLAVQAIR+YG+DF AI++VIGNK++ QVK
Sbjct: 360 KEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKN 419
Query: 369 FFVSYRRRFNLEEVLQEWEA----EQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITS 424
FFV+YRRRFN++EVLQEWEA E+ P P++ +P EE+DE +
Sbjct: 420 FFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMP----EEEDEAPVLD 475
Query: 425 V 425
V
Sbjct: 476 V 476
>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
Length = 436
Score = 385 bits (990), Expect = e-107
Identities = 210/376 (55%), Positives = 265/376 (70%), Gaps = 27/376 (7%)
Query: 1 MPSVMEKPSAGSGILSRSRAK---------------TVPNGGQPHSEDDSS-EEEHSHDS 44
MP +MEK G +L ++R+ + NGG +SE +S + HD
Sbjct: 1 MPGMMEK---GPELLGKNRSANGSAKSPAGGGGSGASSTNGGLHYSEPESGCSSDDEHDV 57
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
+RVG YQA IPE P + +Y++K+ GMLVWSP H + DA+LD+YIA+AKEKHGYN+
Sbjct: 58 GMRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDARLDEYIAIAKEKHGYNV 116
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 117 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 176
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPA 220
I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P
Sbjct: 177 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KK 235
Query: 221 DPKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDL 279
+ K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+
Sbjct: 236 EAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNA 295
Query: 280 ANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLL 339
AN LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLL
Sbjct: 296 ANTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLL 355
Query: 340 AVQAIRRYG-KDFGAI 354
AVQ G D G+I
Sbjct: 356 AVQGTDPTGSSDTGSI 371
Score = 36.6 bits (83), Expect = 0.057
Identities = 14/50 (28%), Positives = 30/50 (60%)
Query: 326 TKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRR 375
T F WT ++++L QA +GK F I +++ +KT+ + ++ S+++
Sbjct: 141 TPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 190
>gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]
Length = 266
Score = 214 bits (545), Expect = 2e-55
Identities = 117/181 (64%), Positives = 127/181 (70%), Gaps = 27/181 (14%)
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
M+RVGTNYQA+IPECKPES ARYSNK+LKG+LVWSPNHCVSDAKLDKYI MA EKHGYNI
Sbjct: 1 MVRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNI 60
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQ LG+ + V L W L Q + IQQ LPDK
Sbjct: 61 EQTLGVDSRGQGAVGTGL------------W------LPRQVW---------IQQTLPDK 93
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKR 224
LI SLVKY+YSWKKT SRTS+ DRQARRL G KDKEDSDE EE RGG+SEGEPD PKR
Sbjct: 94 LISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKR 153
Query: 225 E 225
E
Sbjct: 154 E 154
Score = 157 bits (397), Expect = 2e-38
Identities = 81/97 (83%), Positives = 83/97 (85%)
Query: 350 DFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPL 409
DFGAIAEVIGNKTLTQVKTFFVSY FNLEEVLQEWEAEQDGA GA VP+EEARRGAPL
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQDGARGATVPVEEARRGAPL 228
Query: 410 PAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
APA EED EVQITS+S SV RSVPP P PPPTSL
Sbjct: 229 LAPAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTSL 265
>gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]
Length = 266
Score = 214 bits (545), Expect = 2e-55
Identities = 117/181 (64%), Positives = 127/181 (70%), Gaps = 27/181 (14%)
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
M+RVGTNYQA+IPECKPES ARYSNK+LKG+LVWSPNHCVSDAKLDKYI MA EKHGYNI
Sbjct: 1 MVRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNI 60
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQ LG+ + V L W L Q + IQQ LPDK
Sbjct: 61 EQTLGVDSRGQGAVGTGL------------W------LPRQVW---------IQQTLPDK 93
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKR 224
LI SLVKY+YSWKKT SRTS+ DRQARRL G KDKEDSDE EE RGG+SEGEPD PKR
Sbjct: 94 LISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKR 153
Query: 225 E 225
E
Sbjct: 154 E 154
Score = 157 bits (397), Expect = 2e-38
Identities = 81/97 (83%), Positives = 83/97 (85%)
Query: 350 DFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPL 409
DFGAIAEVIGNKTLTQVKTFFVSY FNLEEVLQEWEAEQDGA GA VP+EEARRGAPL
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQDGARGATVPVEEARRGAPL 228
Query: 410 PAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
APA EED EVQITS+S SV RSVPP P PPPTSL
Sbjct: 229 LAPAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTSL 265
>gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo
sapiens]
Length = 266
Score = 214 bits (545), Expect = 2e-55
Identities = 117/181 (64%), Positives = 127/181 (70%), Gaps = 27/181 (14%)
Query: 45 MIRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNI 104
M+RVGTNYQA+IPECKPES ARYSNK+LKG+LVWSPNHCVSDAKLDKYI MA EKHGYNI
Sbjct: 1 MVRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNI 60
Query: 105 EQALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDK 164
EQ LG+ + V L W L Q + IQQ LPDK
Sbjct: 61 EQTLGVDSRGQGAVGTGL------------W------LPRQVW---------IQQTLPDK 93
Query: 165 LIPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKR 224
LI SLVKY+YSWKKT SRTS+ DRQARRL G KDKEDSDE EE RGG+SEGEPD PKR
Sbjct: 94 LISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKR 153
Query: 225 E 225
E
Sbjct: 154 E 154
Score = 157 bits (397), Expect = 2e-38
Identities = 81/97 (83%), Positives = 83/97 (85%)
Query: 350 DFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPL 409
DFGAIAEVIGNKTLTQVKTFFVSY FNLEEVLQEWEAEQDGA GA VP+EEARRGAPL
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQDGARGATVPVEEARRGAPL 228
Query: 410 PAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
APA EED EVQITS+S SV RSVPP P PPPTSL
Sbjct: 229 LAPAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTSL 265
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 103 bits (256), Expect = 5e-22
Identities = 99/393 (25%), Positives = 165/393 (41%), Gaps = 29/393 (7%)
Query: 135 WTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG 194
W+ ++K F + F H K F I L K + V YYY KK + S++ R RR G
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
Query: 195 GRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLR 254
+ ++ + ++ + + +P P + E + +++ +V + L+
Sbjct: 492 KSQQQQQQQQQQQQQ---QQQQPMPRSSQEEK-DEKEKEKEAEKEEEKPEVENDKEDLLK 547
Query: 255 TRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEG 314
+ G + A G + +SQ R +SM +S E
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGR--------KTANSQGRRKGRITRSMANEANS-----EE 594
Query: 315 GIDPLRPPE-ANTKFN--SRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFV 371
I P + E A+ + N SRWT +E A + + +G+++ AIA ++G+KT++Q K F+
Sbjct: 595 AITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYF 654
Query: 372 SYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPA--PALEEDDEVQITSVSTSV 429
+Y++R NL+E+LQ+ + + + A ++A A A P + ED+E++ + VS +
Sbjct: 655 NYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNE 714
Query: 430 PRSVPPAPPPPPPPTSL-SQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPP 488
V A + S P P T PP G P P PP
Sbjct: 715 EEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN--GPKPPATLGADGPPPGPPTPPPED 772
Query: 489 LIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
+ P P A P PPP AP P AP
Sbjct: 773 IPAPTEPTPASEATGAPTPPP----APPSPSAP 801
Score = 38.5 bits (88), Expect = 0.015
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 34/147 (23%)
Query: 391 DGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS----VPPAPPPPPPPTSL 446
+ +P P+ +++ ++ A P +Q+T V PR PAPP PPPP +L
Sbjct: 937 NASPQKPLDLKQLKQRAAAIPP-------IQVTKVHEP-PREDAAPTKPAPPAPPPPQNL 988
Query: 447 SQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPR-LAPNQPPPPLIRPALAAPRH------ 499
P AP +QP +G+ P A + P+ PA AA
Sbjct: 989 Q--------PESDAP---QQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDP 1037
Query: 500 ----SARPGPQPPPTLIGAPLEPPAPS 522
S P P PP +I A P PS
Sbjct: 1038 PCWTSGLPFPVPPREVIKASPHAPDPS 1064
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPP----------LLRPPLPTAPTLLRQPPPL 470
PR V A P P P++ S PP RP LP PT + PPPL
Sbjct: 1050 PREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT-ISNPPPL 1099
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 99.8 bits (247), Expect = 6e-21
Identities = 100/408 (24%), Positives = 167/408 (40%), Gaps = 42/408 (10%)
Query: 135 WTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG 194
W+ ++K F + F H K F I L K + V YYY KK + S++ R RR G
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
Query: 195 GRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRHHPLR 254
+ ++ + ++ + + +P P + E + +++ +V + L+
Sbjct: 492 KSQQQQQQQQQQQQQ---QQQQPMPRSSQEEK-DEKEKEKEAEKEEEKPEVENDKEDLLK 547
Query: 255 TRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEG 314
+ G + A G + +SQ R +SM +S E
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGR--------KTANSQGRRKGRITRSMANEANS-----EE 594
Query: 315 GIDPLRPPE-ANTKFN--SRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFV 371
I P + E A+ + N SRWT +E A + + +G+++ AIA ++G+KT++Q K F+
Sbjct: 595 AITPQQSAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYF 654
Query: 372 SYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPA--PALEEDDEVQITSVSTSV 429
+Y++R NL+E+LQ+ + + + A ++A A A P + ED+E++ + VS +
Sbjct: 655 NYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNE 714
Query: 430 P-------------RSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQG 473
VP P + S + P A Q PP G
Sbjct: 715 EEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLG 774
Query: 474 RFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
P P PP + P P A P PPP AP P AP
Sbjct: 775 ADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP----APPSPSAP 818
Score = 38.1 bits (87), Expect = 0.020
Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 3/95 (3%)
Query: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
EA +D P P P P P +++ + T + PPP PP S
Sbjct: 757 EAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPP-SP 815
Query: 447 SQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLA 481
S PPP++ P PP+++G +P A
Sbjct: 816 SAPPPVV--PKEEKEEETAAAPPVEEGEEQKPPAA 848
Score = 36.6 bits (83), Expect = 0.057
Identities = 37/143 (25%), Positives = 56/143 (39%), Gaps = 27/143 (18%)
Query: 391 DGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPP 450
+ +P P+ +++ ++ A P + + E + + PAPP PPPP +L
Sbjct: 954 NASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPT-----KPAPPAPPPPQNLQ--- 1005
Query: 451 PLLRPPLPTAPTLLRQPPPLQQGRFLQPR-LAPNQPPPPLIRPALAAPRH---------- 499
P AP +QP +G+ P A + P+ PA AA
Sbjct: 1006 -----PESDAP---QQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWT 1057
Query: 500 SARPGPQPPPTLIGAPLEPPAPS 522
S P P PP +I A P PS
Sbjct: 1058 SGLPFPVPPREVIKASPHAPDPS 1080
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 11/51 (21%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPP----------LLRPPLPTAPTLLRQPPPL 470
PR V A P P P++ S PP RP LP PT + PPPL
Sbjct: 1066 PREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT-ISNPPPL 1115
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 85.5 bits (210), Expect = 1e-16
Identities = 78/340 (22%), Positives = 138/340 (40%), Gaps = 21/340 (6%)
Query: 131 FPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQA 190
F + WT +K +F+ F H K F I L K +P V YYY KK + +++ R
Sbjct: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
Query: 191 RRLGGRKDKEDSDELEEGRGGVSEGEPDPADPKREPLPSRPLNARPGPGKKEVQVSQYRH 250
+ GR + EE V E E D A+ + + + + ++ +
Sbjct: 496 GKRRGRNQQIARPSQEEK---VEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKD 552
Query: 251 HPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLRQ 310
T + +P G + R + ++ + +++
Sbjct: 553 KIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAA----------ASAAAAA 602
Query: 311 ALEGGIDPLRPP----EANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQV 366
A E PL PP SRWT +E +A + + +G+++ AIA+++G K+ Q
Sbjct: 603 ATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQC 662
Query: 367 KTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEV--QITS 424
K F+ +Y+RR NL+ +LQ+ + + P + + A + +ED E + +
Sbjct: 663 KNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEEN 722
Query: 425 VSTSVPRSVPPAPPPPPPPTSL--SQPPPLLRPPLPTAPT 462
S +V P+ P TS ++P L P TAP+
Sbjct: 723 PEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPS 762
Score = 35.8 bits (81), Expect = 0.098
Identities = 43/200 (21%), Positives = 80/200 (40%), Gaps = 24/200 (12%)
Query: 135 WTVEDKVLFEQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKKTRSRTSVMDRQARRLG 194
WT E+ + ++ HG+ + I +M+ K +Y+++K+ + +++ +Q ++
Sbjct: 628 WTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLL-QQHKQKT 686
Query: 195 GRKDKEDSD--ELEEGRGGVSEGEPDPADPKRE---PLPSRPLNARPGPGKKEVQVSQYR 249
RK +E+ D + E VS E + + E P S +P E S+
Sbjct: 687 SRKPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEVEAVKPSEDSPENATSRGN 746
Query: 250 HHPLRTRRRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLI------SLKRQVQSMKQ 303
P + L P TA S SP LA + + + + + S+ +
Sbjct: 747 TEP---------AVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQMD 797
Query: 304 TNSSLRQALEGGI-DPLRPP 322
+ A EG + DP PP
Sbjct: 798 VDQQEHSAEEGSVCDP--PP 815
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 66.2 bits (160), Expect = 7e-11
Identities = 54/139 (38%), Positives = 60/139 (43%), Gaps = 31/139 (22%)
Query: 391 DGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP--TSLSQ 448
DG P AP A P P P L + S T P + PPP PPP T Q
Sbjct: 1420 DGPPLAPA----AAVPGPPPLPGLPSAN-----SNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
Query: 449 PPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPP 508
PPP PP P P+ PPPL + P P+ PPPP + P P A P P PP
Sbjct: 1471 PPPPPPPPQPALPS----PPPL-----VAP--TPSSPPPPPLPP----PPPPAMPSPPPP 1515
Query: 509 PTLIGAPL-----EPPAPS 522
P APL EP APS
Sbjct: 1516 PPPAAAPLAAPPEEPAAPS 1534
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/126 (35%), Positives = 48/126 (38%), Gaps = 28/126 (22%)
Query: 392 GAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPP------PPP--- 442
G P P G P P P LEE T P+ PP PPP PPP
Sbjct: 1432 GPPPLPGLPSANSNGTPEP-PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVA 1490
Query: 443 PTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSAR 502
PT S PPP L PP P A + PPP PPPP P A P A
Sbjct: 1491 PTPSSPPPPPLPPPPPPA---MPSPPP---------------PPPPAAAPLAAPPEEPAA 1532
Query: 503 PGPQPP 508
P P+ P
Sbjct: 1533 PSPEDP 1538
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/169 (29%), Positives = 68/169 (40%), Gaps = 30/169 (17%)
Query: 377 FNLEEVLQEWEAEQDGAPGAPVPM----EEARRGAP-LPAPALEEDDEV-QITSVSTSVP 430
F L L+ E+E G G P P EE +R LP+ + +E+D V + + S+
Sbjct: 1341 FGLGGALEAAESEGLGL-GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESIS 1399
Query: 431 RSVPPAPPPP---PPPTSLSQPPPLLR-------PPLPTAPTLLRQPPPLQQGRFLQPRL 480
++ PP P TS PPL PPLP P+ P +P L
Sbjct: 1400 SAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP-------EPPL 1452
Query: 481 APNQPPP-----PLIRPALAAPRHSARPG-PQPPPTLIGAPLEPPAPSL 523
+PPP P +P P +P P PPP + P PP P L
Sbjct: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPL 1501
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/108 (35%), Positives = 45/108 (41%), Gaps = 26/108 (24%)
Query: 436 APPPPPPPTSLSQPPP---LLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPP---- 488
+PPPPPP +QP P LL P P +L PPP L P + + P P
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQ-----LLPSVLSHAPSPSPSAS 817
Query: 489 -----LIRPAL--AAPRHSARPGPQPPPT-------LIGAPLEPPAPS 522
L+ PA AP+ P P PPP L LEP APS
Sbjct: 818 KVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS 865
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 9/79 (11%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPP---------PPPPT 444
P AP P + P P PAL + + S+ P +PP PPP PP
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAA 1521
Query: 445 SLSQPPPLLRPPLPTAPTL 463
L+ PP P P P L
Sbjct: 1522 PLAAPPEEPAAPSPEDPEL 1540
Score = 39.7 bits (91), Expect = 0.007
Identities = 38/137 (27%), Positives = 49/137 (35%), Gaps = 7/137 (5%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLL 453
P P + AP P+P+ + + + PP PPPPPPP L L
Sbjct: 796 PPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR 855
Query: 454 RPPL-PTAPT-LLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGP-----Q 506
L P AP+ LR L +Q L +P PP P +S P
Sbjct: 856 SHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRS 915
Query: 507 PPPTLIGAPLEPPAPSL 523
P P AP P S+
Sbjct: 916 PSPQGTKAPRFVPLTSI 932
Score = 35.0 bits (79), Expect = 0.17
Identities = 29/91 (31%), Positives = 33/91 (36%), Gaps = 10/91 (10%)
Query: 434 PPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPA 493
P P PPPPP L LL A + P L + AP PPP P
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQL----YNFSGAAPGPPPPERALPR 284
Query: 494 L-AAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
+H RP PP P PPA +L
Sbjct: 285 QDTVIKHYQRPASAQPP-----PPPPPAHAL 310
Score = 35.0 bits (79), Expect = 0.17
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 37/172 (21%)
Query: 307 SLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLA--VQAIRRYGKDFGAIAEVIG--NKT 362
SL+ AL+ G +P PP W + LL I+ + F A + +G
Sbjct: 1589 SLKLALQTGREP--PPI--------WRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDA 1638
Query: 363 LTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQI 422
+ + +V + N ++ ++ + P PV RR P +
Sbjct: 1639 KNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPV-----RRSGQAKNP---------V 1684
Query: 423 TSVSTSVPRSVPPAPPPPP--PPTSLSQPPP-------LLRPPLPTAPTLLR 465
++ +S P PAPPP P P + S+ PP + PP P P+LLR
Sbjct: 1685 SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR 1736
Score = 34.7 bits (78), Expect = 0.22
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 12/50 (24%)
Query: 434 PPAPPPPPPPTSLSQPPPLLRPPL--PTAP----------TLLRQPPPLQ 471
PP PPPPPPP S+P L P+ T P L R+ PP Q
Sbjct: 1040 PPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
Score = 33.5 bits (75), Expect = 0.49
Identities = 28/92 (30%), Positives = 30/92 (32%), Gaps = 8/92 (8%)
Query: 434 PPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPA 493
P A PPP PP P P P P G L P P P P
Sbjct: 974 PKAGAGPPPG------PPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 494 --LAAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
+ + H A P P PPP AP P L
Sbjct: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGL 1059
Score = 33.5 bits (75), Expect = 0.49
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 4/73 (5%)
Query: 451 PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPT 510
P RPP+P + + P G P AP PP +P S +P Q P T
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP----KPETPEKTTSEKPPEQTPET 1721
Query: 511 LIGAPLEPPAPSL 523
+ P P PSL
Sbjct: 1722 AMPEPPAPEKPSL 1734
Score = 33.1 bits (74), Expect = 0.64
Identities = 16/54 (29%), Positives = 24/54 (44%)
Query: 425 VSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQP 478
VS + PP P PPP + +PP T T + +PP ++ L+P
Sbjct: 1684 VSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRP 1737
Score = 30.4 bits (67), Expect = 4.1
Identities = 36/150 (24%), Positives = 49/150 (32%), Gaps = 25/150 (16%)
Query: 392 GAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL----- 446
G AP P AP P P E ++ P + P PP P P+ L
Sbjct: 1687 GGSSAPPPK------APAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740
Query: 447 -------SQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL-------APNQPPPPLIRP 492
++ LR T+ R L G+ RL +PPP +
Sbjct: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK 1800
Query: 493 ALAAPRHSARPGPQPPPTLIGAPLEPPAPS 522
L +A G PP + + P APS
Sbjct: 1801 WLKEAGGNATAGGGPPGSSSDSESSPGAPS 1830
Score = 29.6 bits (65), Expect = 7.0
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 3/47 (6%)
Query: 465 RQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPG-PQPPPT 510
R PP Q G L P L+P + PP + P+ A P P PPP+
Sbjct: 1294 RHPPLYQAG--LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPS 1338
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 65.9 bits (159), Expect = 9e-11
Identities = 82/338 (24%), Positives = 121/338 (35%), Gaps = 64/338 (18%)
Query: 201 DSDELEEGRGGVSEGEPDPAD----PKREPLPSRPLNARPGPGKKEVQVSQYRHHPLRTR 256
D++ +E G P+P D P E P+ P + + + + L
Sbjct: 458 DTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFL 517
Query: 257 RRPPKGMYLSPEGLTAVSGSPDLANLTLRGLDSQLISLKRQVQSMKQTNSSLR------- 309
R P L EG S S L+ L G +SQ S + +++ L
Sbjct: 518 REPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL 577
Query: 310 ------QALEGGIDPLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTL 363
+ L+ G+ P PPE + + +A+ +++G++T
Sbjct: 578 PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL--------------DLVGDRTP 623
Query: 364 TQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQIT 423
T S + + ++ E D P AP+ A P P + V
Sbjct: 624 T-------SEKMDEGQQSSGEDMEISDDEMPSAPIT------SADCPKPMV-----VTPG 665
Query: 424 SVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPN 483
+ + + P + P P PPPP PPP PP PPP Q G + P L P
Sbjct: 666 AAAVAAPSVLAPTLPLPPPPGFPPLPPP---PP----------PPPPQPGFPMPPPLPPP 712
Query: 484 QPPPPLIRPALAAPRH--SARPGPQPPPTLIGAPLEPP 519
PPPP PA+ P A PG PPP L P PP
Sbjct: 713 PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750
Score = 43.5 bits (101), Expect = 5e-04
Identities = 43/157 (27%), Positives = 56/157 (35%), Gaps = 36/157 (22%)
Query: 389 EQDG-----APGAP----VPMEE-----ARRGAPLPAPALEEDDEVQITSVSTSVPRSVP 434
EQDG APGAP + MEE AP P++ ++ + + + R P
Sbjct: 1167 EQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPP 1226
Query: 435 PAP----------PPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ 484
P P PP + PPL P + PP+ LQP L P +
Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR 1286
Query: 485 PPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
PP P P P+P T P PP P
Sbjct: 1287 PPRP------------PSPPPEPETTDASHPSVPPEP 1311
Score = 42.7 bits (99), Expect = 8e-04
Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 31/153 (20%)
Query: 389 EQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQ 448
E+ G +PV +E G PLP P L + + +V + R+ P PP P P + S
Sbjct: 1414 ERSGPLASPVLLET---GLPLPLP-LPLPLPLALPAVLRAQARAPTPLPPLLPAPLA-SC 1468
Query: 449 PPPLLRPP----------LPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPR 498
PPP+ R P L L+R P GR L L P QP P+ P+ PR
Sbjct: 1469 PPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELL--LLPGQPQTPVF-PSTHDPR 1525
Query: 499 -------HSARPGP------QPPPTLIGAPLEP 518
++ P P QPPP P+EP
Sbjct: 1526 TVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEP 1558
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/46 (43%), Positives = 21/46 (45%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRF 475
P PP PPPP P PPPL PP P +L PP G F
Sbjct: 708 PLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLF 753
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 22/143 (15%)
Query: 399 PMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS---------------VPPAPPPPPPP 443
P G P PA L + EV + V P S + P P
Sbjct: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPI 651
Query: 444 TSLSQPPPLLRPP---LPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHS 500
TS P P++ P AP++L PL P P PPPP P P
Sbjct: 652 TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP----PPGFPPLPPPPPPPPPQPGFPMPP 707
Query: 501 ARPGPQPPPTLIGAPLEPPAPSL 523
P P PPP + P P L
Sbjct: 708 PLPPPPPPPPPAHPAVTVPPPPL 730
Score = 37.0 bits (84), Expect = 0.044
Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 14/143 (9%)
Query: 390 QDGA----PGAPVPMEEARRG-APLPAPA--LEEDDEVQITSVSTSVPRSVPPAPPPPPP 442
Q+GA P P EAR +P AP LE + E + P PP PP PP
Sbjct: 1233 QEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPS 1292
Query: 443 PTSLSQPPPLLRPPLPTAPTLLRQPP--PLQQGRFLQPRLAPNQPPPPLIRPALAAPRHS 500
P + P +P P PP P G + + P P P L+
Sbjct: 1293 PPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSG 1352
Query: 501 -ARPGPQPPPTLIGAPLEPPAPS 522
+ PQ P G+P PAPS
Sbjct: 1353 LSLSSPQVP----GSPFSYPAPS 1371
Score = 37.0 bits (84), Expect = 0.044
Identities = 40/147 (27%), Positives = 53/147 (36%), Gaps = 19/147 (12%)
Query: 394 PGAPVPMEEARRGA--PLPAPALEEDDEVQITSVSTSVPRS-----VPPAPPPPPPPTSL 446
P +P P E + +P L ED + S+ +S VP P PP +
Sbjct: 1290 PPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGG 1349
Query: 447 SQPPPLLRPPLPTAPTLLRQPP--------PLQQGRFLQPRLAPNQPPPPLIRPALAAP- 497
S L P +P +P P P GR ++P PL+ P P
Sbjct: 1350 SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPT 1409
Query: 498 -RHSARPGPQPPPTLI--GAPLEPPAP 521
R R GP P L+ G PL P P
Sbjct: 1410 GRRDERSGPLASPVLLETGLPLPLPLP 1436
Score = 35.0 bits (79), Expect = 0.17
Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 26/89 (29%)
Query: 430 PRSVPPAPPPPPPPTSL-----------SQPPPLLRPPLPTAPTLL-------------- 464
P +PP PPPPPPP + +Q P PP P +
Sbjct: 1540 PPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPW 1599
Query: 465 RQPPPLQQGRFLQPRLAPN-QPPPPLIRP 492
R+PP + + P +P PP PL RP
Sbjct: 1600 RRPPKKRHEDLVPPAGSPELSPPQPLFRP 1628
Score = 34.7 bits (78), Expect = 0.22
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 24/113 (21%)
Query: 412 PALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQP---- 467
P+ + V + + +P PP PP PPPP PPP+ LP + P
Sbjct: 1519 PSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP---PPPPPVEPTKLPFKELDNQWPSEAI 1575
Query: 468 PPLQQGR---------FLQPRLAPNQPP--------PPLIRPALAAPRHSARP 503
PP +GR + R +PP PP P L+ P+ RP
Sbjct: 1576 PPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRP 1628
Score = 29.6 bits (65), Expect = 7.0
Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 7/135 (5%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPP---PPTSLSQPP 450
PG P+ G L +P + + S S+ P P PT
Sbjct: 1340 PGGEPPLSGGSSGLSLSSPQVP-GSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSG 1398
Query: 451 PLLRP--PLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPP 508
PLL P PLPT R P L L+ L P P + AL A + P P
Sbjct: 1399 PLLLPVCPLPTGRRDERSGP-LASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPL 1457
Query: 509 PTLIGAPLEPPAPSL 523
P L+ APL P +
Sbjct: 1458 PPLLPAPLASCPPPM 1472
Score = 29.3 bits (64), Expect = 9.2
Identities = 24/83 (28%), Positives = 32/83 (38%), Gaps = 10/83 (12%)
Query: 435 PAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPAL 494
PAPPP PP L++ +P P P PPP L R P P P
Sbjct: 432 PAPPPLPPAEPLAKE----KPGTPPGP-----PPPDTNSMELGGRPTFGWSPEPCDSPG- 481
Query: 495 AAPRHSARPGPQPPPTLIGAPLE 517
S+ GP+ P + + +E
Sbjct: 482 TPTLESSPAGPEKPHDSLDSRIE 504
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 64.3 bits (155), Expect = 3e-10
Identities = 47/141 (33%), Positives = 54/141 (38%), Gaps = 23/141 (16%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
A VP R PAP L D I + PP PPPPPPP PPPL
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP-----PPPL 612
Query: 453 ------LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPG-- 504
PP T + PPPL + PPPP + + P S+ PG
Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDATI--------PPPPPLPEGVGIPSPSSLPGGT 664
Query: 505 --PQPPPTLIGAPLEPPAPSL 523
P PPP A + PP P L
Sbjct: 665 AIPPPPPLPGSARIPPPPPPL 685
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 22/127 (17%)
Query: 395 GAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLR 454
G +P + G P +I +P S PPPPP P PPP
Sbjct: 651 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP--P 708
Query: 455 PPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIGA 514
PPLP P + PPP G P PPPP P + P PPP G
Sbjct: 709 PPLPGGPG-IPPPPPFPGG--------PGIPPPP---PGMGM--------PPPPPFGFGV 748
Query: 515 PLEPPAP 521
P P P
Sbjct: 749 PAAPVLP 755
Score = 31.6 bits (70), Expect = 1.8
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 20/101 (19%)
Query: 397 PVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPP--------PPPPTSLSQ 448
P P G P P P L E + +P PPP PPPP +
Sbjct: 681 PPPPLPGSAGIPPPPPPLP--GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM 738
Query: 449 PPPLLRPP----LPTAPTLLRQPPPLQQGRFLQPRLAPNQP 485
PPP PP +P AP L P L + +P + +P
Sbjct: 739 PPP---PPFGFGVPAAPVL---PFGLTPKKLYKPEVQLRRP 773
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 64.3 bits (155), Expect = 3e-10
Identities = 47/141 (33%), Positives = 54/141 (38%), Gaps = 23/141 (16%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
A VP R PAP L D I + PP PPPPPPP PPPL
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP-----PPPL 621
Query: 453 ------LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPG-- 504
PP T + PPPL + PPPP + + P S+ PG
Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATI--------PPPPPLPEGVGIPSPSSLPGGT 673
Query: 505 --PQPPPTLIGAPLEPPAPSL 523
P PPP A + PP P L
Sbjct: 674 AIPPPPPLPGSARIPPPPPPL 694
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 22/127 (17%)
Query: 395 GAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLR 454
G +P + G P +I +P S PPPPP P PPP
Sbjct: 660 GVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP--P 717
Query: 455 PPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIGA 514
PPLP P + PPP G P PPPP P + P PPP G
Sbjct: 718 PPLPGGPG-IPPPPPFPGG--------PGIPPPP---PGMGM--------PPPPPFGFGV 757
Query: 515 PLEPPAP 521
P P P
Sbjct: 758 PAAPVLP 764
Score = 31.6 bits (70), Expect = 1.8
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 20/101 (19%)
Query: 397 PVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPP--------PPPPTSLSQ 448
P P G P P P L E + +P PPP PPPP +
Sbjct: 690 PPPPLPGSAGIPPPPPPLP--GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGM 747
Query: 449 PPPLLRPP----LPTAPTLLRQPPPLQQGRFLQPRLAPNQP 485
PPP PP +P AP L P L + +P + +P
Sbjct: 748 PPP---PPFGFGVPAAPVL---PFGLTPKKLYKPEVQLRRP 782
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 64.3 bits (155), Expect = 3e-10
Identities = 46/138 (33%), Positives = 55/138 (39%), Gaps = 17/138 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + P +P A PPPPP + PP
Sbjct: 1037 PGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ---PPPPLIRPALAAPRHSARP 503
PL + PP P + PPPL P P PPPPL + P R
Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV 1149
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1150 GIPPPPPLPGAGIPPPPP 1167
Score = 64.3 bits (155), Expect = 3e-10
Identities = 46/138 (33%), Positives = 55/138 (39%), Gaps = 17/138 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + P +P A PPPPP + PP
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ---PPPPLIRPALAAPRHSARP 503
PL + PP P + PPPL P P PPPPL R + P
Sbjct: 1101 PLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1161 GIPPPPPLPGAGIPPPPP 1178
Score = 63.5 bits (153), Expect = 4e-10
Identities = 45/138 (32%), Positives = 55/138 (39%), Gaps = 17/138 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + +P +P A PPPPP + PP
Sbjct: 938 PGAGIPPPPPLPGAAIPPPP-------PLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ---PPPPLIRPALAAPRHSARP 503
PL + PP P + PPPL P P PPPPL + P
Sbjct: 991 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1050
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1051 GIPPPPPLPGAGIPPPPP 1068
Score = 63.2 bits (152), Expect = 6e-10
Identities = 47/138 (34%), Positives = 55/138 (39%), Gaps = 17/138 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + V P +P A PPPPP + PP
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPP-------PLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133
Query: 451 PLLRPPLPTAPTLLR----QPPPLQQGRFLQPRLAPNQ---PPPPLIRPALAAPRHSARP 503
PL +P P L R PPPL P P PPPPL + P
Sbjct: 1134 PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGV 1193
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1194 GIPPPPPLPGAGIPPPPP 1211
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/138 (33%), Positives = 55/138 (39%), Gaps = 17/138 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPA--PPPPP-PPTSLSQPP 450
PGA +P GA +P P + P +P A PPPPP P + PP
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPN---QPPPPLIRPALAAPRHSARP 503
PL + PP P + PPPL P P PPPPL + P
Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1128 GIPPPPPLPGAGIPPPPP 1145
Score = 59.7 bits (143), Expect = 6e-09
Identities = 46/139 (33%), Positives = 55/139 (39%), Gaps = 21/139 (15%)
Query: 397 PVPMEEARRGAP----LPAPALEEDDEVQITSVSTSVPRSVP-------PAPPPPPPPTS 445
P+P E+ P +P P T ST++P+ P P PPPP P
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919
Query: 446 LSQPPPLLRP---PLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSAR 502
+ PPPL PLP P PPP G A PPPPL + P
Sbjct: 920 IPPPPPLPGAGILPLPPLPGAGIPPPPPLPG-------AAIPPPPPLPGAGIPLPPPLPG 972
Query: 503 PGPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 973 AGIPPPPPLPGAGIPPPPP 991
Score = 59.7 bits (143), Expect = 6e-09
Identities = 46/139 (33%), Positives = 55/139 (39%), Gaps = 19/139 (13%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + P +P A PPPPP + PP
Sbjct: 949 PGAAIPPPPPLPGAGIPLPP-------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ--PPPPLIRPALAAPRHSARPG 504
PL + PP P + PPPL P P PPPP + P P PG
Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPG 1060
Query: 505 P--QPPPTLIGAPLEPPAP 521
PPP L GA + PP P
Sbjct: 1061 AGIPPPPPLPGAGIPPPPP 1079
Score = 59.3 bits (142), Expect = 8e-09
Identities = 45/142 (31%), Positives = 55/142 (38%), Gaps = 19/142 (13%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + P +P A PPPPP + PP
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPP-------PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPN---QPPPPLIRPALAAPRHSARP 503
PL + PP P + PPPL P P PPPPL + P
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGA 1171
Query: 504 GPQPPPTL--IGAPLEPPAPSL 523
G PPP L +G P PP P +
Sbjct: 1172 GIPPPPPLPGVGIPPPPPLPGV 1193
Score = 58.5 bits (140), Expect = 1e-08
Identities = 46/149 (30%), Positives = 57/149 (38%), Gaps = 29/149 (19%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---------- 443
PG VP LP+ A+ + +Q T + P +P A PPPPP
Sbjct: 884 PGMTVPT--------LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935
Query: 444 ----TSLSQPPPLLRPPLPTAPTL----LRQPPPLQQGRFLQPRLAPNQ---PPPPLIRP 492
+ PPPL +P P L + PPPL P P PPPPL
Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995
Query: 493 ALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
+ P G PPP L GA + PP P
Sbjct: 996 GIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Score = 58.2 bits (139), Expect = 2e-08
Identities = 48/138 (34%), Positives = 55/138 (39%), Gaps = 28/138 (20%)
Query: 394 PGAPVPMEEARRGAP-LPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
PGA +P GA LP P L +P PPPP P ++ PPPL
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLP----------GAGIP------PPPPLPGAAIPPPPPL 959
Query: 453 ------LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQ---PPPPLIRPALAAPRHSARP 503
L PPLP A + PPPL P P PPPPL + P
Sbjct: 960 PGAGIPLPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 504 GPQPPPTLIGAPLEPPAP 521
G PPP L GA + PP P
Sbjct: 1018 GIPPPPPLPGAGIPPPPP 1035
Score = 56.6 bits (135), Expect = 5e-08
Identities = 51/148 (34%), Positives = 60/148 (40%), Gaps = 20/148 (13%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQIT---SVSTSVPRSVPPAPPPPPPPTSLSQ-- 448
P P + A +G P P E Q + SVS++ S PPP P T S
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870
Query: 449 ---------PPPLLRPPLPTAP-TLLRQPPPLQQGRFLQPRLAP----NQPPPPLIRPAL 494
PPPL +PT P T + QPPPLQ L P P PPPP + A
Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAG 930
Query: 495 AAPRHS-ARPGPQPPPTLIGAPLEPPAP 521
P G PPP L GA + PP P
Sbjct: 931 ILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Score = 52.8 bits (125), Expect = 8e-07
Identities = 43/136 (31%), Positives = 51/136 (37%), Gaps = 16/136 (11%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP---TSLSQPP 450
PGA +P GA +P P + V P +P A PPPPP + PP
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPP-------PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
Query: 451 PL----LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQ 506
PL + PP P + PPPL P P PP P L P P P
Sbjct: 1178 PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPL 1237
Query: 507 PPPTLIGAPLEPPAPS 522
P + G PL P S
Sbjct: 1238 LP--VSGPPLLPQVGS 1251
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 5/109 (4%)
Query: 394 PGAPVPMEEARRGA----PLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQP 449
PGA +P GA P P P + + V P +P A PPPPP
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Query: 450 PPLLRPPLPTAPTLLRQPPPLQ-QGRFLQPRLAPNQPPPPLIRPALAAP 497
PP PPLP T + PP L G L P++ + P P + L P
Sbjct: 1218 PPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
Score = 40.8 bits (94), Expect = 0.003
Identities = 44/157 (28%), Positives = 53/157 (33%), Gaps = 26/157 (16%)
Query: 391 DGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAP--PPPPPPTSL-- 446
DG PG P P P E V +S + P PPPPP+ L
Sbjct: 761 DGLPGRP-PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWS 819
Query: 447 -------SQPPPLLRPPLPTA-----------PTLLRQPPPLQ--QGRFLQPRLAPNQPP 486
SQPP + T+ + PPPL + P L PP
Sbjct: 820 AGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879
Query: 487 PPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
PP P + P + PQPPP L PP P L
Sbjct: 880 PPP-LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Score = 39.7 bits (91), Expect = 0.007
Identities = 31/104 (29%), Positives = 36/104 (34%), Gaps = 22/104 (21%)
Query: 394 PGAPVPMEEARRGA------PLPAPALEEDDEVQITSVSTSVP---RSVPPAPPPPPPPT 444
PGA +P G PLP + + + P +PPAP PP PP
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228
Query: 445 SLSQPPPLLRP-------------PLPTAPTLLRQPPPLQQGRF 475
PPP L P LPT PPPL G F
Sbjct: 1229 GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLF 1272
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 63.9 bits (154), Expect = 3e-10
Identities = 42/116 (36%), Positives = 46/116 (39%), Gaps = 25/116 (21%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL--------- 480
P VPP+PP PP + + PPP PPL P L +PPP P L
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537
Query: 481 ----APNQP-----------PPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
AP P PPP P LAAP P P PTL AP PP P
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL-QAPRRPPTP 592
Score = 63.5 bits (153), Expect = 4e-10
Identities = 49/136 (36%), Positives = 57/136 (41%), Gaps = 14/136 (10%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVP---PAPPPPPPPTSLSQP 449
AP +P P P+P V + S P S P P PP PP S S
Sbjct: 407 APPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 450 PPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAA-PRHSARPGPQPP 508
PP PP AP L P P P ++P+ PPP P LAA P A+P PQ P
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 509 PTLIGAPLE----PPA 520
P L PL+ PPA
Sbjct: 521 PALATPPLQALPSPPA 536
Score = 57.4 bits (137), Expect = 3e-08
Identities = 46/139 (33%), Positives = 60/139 (43%), Gaps = 10/139 (7%)
Query: 390 QDGAPGAPVPMEEARRGAPLPAPALEEDDEVQI------TSVSTSVPRSVPPAPPPPPPP 443
+D AP A P+ + P P+ AL+ + +S++ + +P APP P P
Sbjct: 290 KDAAP-ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348
Query: 444 TSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFL-QPRLAPNQPPPPLIRPALAAPRHSAR 502
SL P P A T L P FL P L+P PPP PALA P A
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
Query: 503 PGPQPPPTLIGAPLEPPAP 521
P P P L +PL P+P
Sbjct: 409 PSPPASPPL--SPLATPSP 425
Score = 52.0 bits (123), Expect = 1e-06
Identities = 46/149 (30%), Positives = 57/149 (38%), Gaps = 24/149 (16%)
Query: 397 PVPMEEARRGAP-----LPAPALEEDDE---------VQITSVSTSVPRSVPPAPPPPPP 442
P+P+ AP LP+P + +Q T P P A PPP
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396
Query: 443 PTSLSQPP------PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPP---PLIRPA 493
P +L+ PP P PPL T Q P LQ +P PP P PA
Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456
Query: 494 LAAPRHSARPGPQPPPTLIGAPLE-PPAP 521
SA P Q PP+L PL+ PP+P
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/123 (33%), Positives = 56/123 (45%), Gaps = 11/123 (8%)
Query: 394 PGAPVPME----EARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQP 449
P AP P+ + + P PAL + S S P P +P P + L+ P
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 450 PPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPR--HSARPGPQP 507
PP PP+ AP LL+ PP LQ AP +PP P +++ PR + PGP P
Sbjct: 559 PP-QAPPVLAAP-LLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Query: 508 PPT 510
PP+
Sbjct: 614 PPS 616
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/126 (30%), Positives = 43/126 (34%), Gaps = 13/126 (10%)
Query: 394 PGAPV-PMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
P P P +A R P P P S S PR P PPPP S S L
Sbjct: 575 PSPPASPTLQAPRRPPTPGP-----------DTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLI 512
P L + P +G P PPP A P +R GP PP
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFR 682
Query: 513 GAPLEP 518
GAP P
Sbjct: 683 GAPGAP 688
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.9 bits (154), Expect = 3e-10
Identities = 42/116 (36%), Positives = 46/116 (39%), Gaps = 25/116 (21%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRL--------- 480
P VPP+PP PP + + PPP PPL P L +PPP P L
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498
Query: 481 ----APNQP-----------PPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
AP P PPP P LAAP P P PTL AP PP P
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL-QAPRRPPTP 553
Score = 63.5 bits (153), Expect = 4e-10
Identities = 49/136 (36%), Positives = 57/136 (41%), Gaps = 14/136 (10%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVP---PAPPPPPPPTSLSQP 449
AP +P P P+P V + S P S P P PP PP S S
Sbjct: 368 APPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
Query: 450 PPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAA-PRHSARPGPQPP 508
PP PP AP L P P P ++P+ PPP P LAA P A+P PQ P
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 509 PTLIGAPLE----PPA 520
P L PL+ PPA
Sbjct: 482 PALATPPLQALPSPPA 497
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/138 (33%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 392 GAPGAPV----PMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVP-PAPPPPP--PPT 444
G P AP P + + P D +S P + P P+ PP P PP+
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311
Query: 445 SLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFL-QPRLAPNQPPPPLIRPALAAPRHSARP 503
+ P P PP A T L P FL P L+P PPP PALA P A P
Sbjct: 312 LQTLPSPPATPP-SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 504 GPQPPPTLIGAPLEPPAP 521
P P L +PL P+P
Sbjct: 371 SPPASPPL--SPLATPSP 386
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/123 (33%), Positives = 56/123 (45%), Gaps = 11/123 (8%)
Query: 394 PGAPVPME----EARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQP 449
P AP P+ + + P PAL + S S P P +P P + L+ P
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 450 PPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPR--HSARPGPQP 507
PP PP+ AP LL+ PP LQ AP +PP P +++ PR + PGP P
Sbjct: 520 PP-QAPPVLAAP-LLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 508 PPT 510
PP+
Sbjct: 575 PPS 577
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 10/112 (8%)
Query: 420 VQITSVSTSVPRSVPPAPPPPPPPTSLSQPP------PLLRPPLPTAPTLLRQPPPLQQG 473
+Q T P P A PPP P +L+ PP P PPL T Q P
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 474 RFLQPRLAPNQPPP---PLIRPALAAPRHSARPGPQPPPTLIGAPLE-PPAP 521
LQ +P PP P PA SA P Q PP+L PL+ PP+P
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/126 (30%), Positives = 43/126 (34%), Gaps = 13/126 (10%)
Query: 394 PGAPV-PMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
P P P +A R P P P S S PR P PPPP S S L
Sbjct: 536 PSPPASPTLQAPRRPPTPGP-----------DTSVSGPRLTLALAPGPPPPPSRSPSSTL 584
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLI 512
P L + P +G P PPP A P +R GP PP
Sbjct: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFR 643
Query: 513 GAPLEP 518
GAP P
Sbjct: 644 GAPGAP 649
Score = 38.9 bits (89), Expect = 0.012
Identities = 33/94 (35%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 430 PRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPL 489
P+ PP P LS P L P P+AP PP LQ P P+Q L
Sbjct: 274 PQVTPPRKDAAPALGPLSSSP--LATPSPSAPPSPSAPPSLQTLPS-PPATPPSQATTSL 330
Query: 490 IRPALAAPRHSARPGPQPPPTLIGAPLEPPAPSL 523
P L A HS P P P P PPA +L
Sbjct: 331 GSPTLQAT-HSFLPSPPLSPLATPPPQAPPALAL 363
Score = 33.9 bits (76), Expect = 0.37
Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 25/127 (19%)
Query: 403 ARRGAPLPAPALEEDDEVQITSVST---SVPRSVPPAPPPPPPPTSLSQPPP----LLRP 455
A R P L+ ++S +T S RS P A P P SQP P LRP
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273
Query: 456 PLPTAPTLLRQPP--PLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIG 513
P T P P PL P +P+ PP P SA P Q TL
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATP--SPSAPPSP-----------SAPPSLQ---TLPS 317
Query: 514 APLEPPA 520
P PP+
Sbjct: 318 PPATPPS 324
Score = 29.6 bits (65), Expect = 7.0
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 14/85 (16%)
Query: 434 PPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRF-------LQPRLAPNQP- 485
PP P PPPP + P LR L A + R+P + G PR P +
Sbjct: 29 PPGSPRPPPPVT----PAALR-VLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83
Query: 486 -PPPLIRPALAAPRHSARPGPQPPP 509
PP R A P + PGP P
Sbjct: 84 RPPASGRGERAPPAKNTSPGPVSSP 108
>gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]
Length = 515
Score = 63.9 bits (154), Expect = 3e-10
Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 33/167 (19%)
Query: 46 IRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKE------- 98
IRVG YQA IPE E + + + VW PN ++D ++D+++ +A+
Sbjct: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
Query: 99 -------------------KHGYNIEQALGMLLWHKHDVEKSLADLANF------TPFPD 133
+ A+ L H +D+ +++ L +
Sbjct: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
Query: 134 EWTVEDKVLFEQAFGFHGKCFQRIQQ-MLPDKLIPSLVKYYYSWKKT 179
EW+ + LFE+A +GK F I+Q LP K + S+++YYY WK T
Sbjct: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 318 PLRPPEANTKFNSRWTTDEQLLAVQAIRRYGKDFGAI-AEVIGNKTLTQVKTFFVSYRR- 375
PL P W+ E L +A+ +YGKDF I + + K+LT + ++ ++
Sbjct: 257 PLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
Query: 376 -RFNLEEVLQEWEAE 389
R+ ++ L+ EAE
Sbjct: 317 DRYVQQKRLKAAEAE 331
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 63.2 bits (152), Expect = 6e-10
Identities = 60/215 (27%), Positives = 88/215 (40%), Gaps = 34/215 (15%)
Query: 46 IRVGTNYQAVIPECKPESPARYSNKELKGMLVWSP-----NHCVS---DAKLDKYIAMAK 97
I +G +QA IPE + S K LVW P NH + + L+ + A
Sbjct: 781 INIGLRFQAEIPELQDISALAQDTH--KATLVWKPWPELENHDLQQRVENLLNLCCSSAL 838
Query: 98 EKHGYNIEQALGMLLWHKHDVEKSLADLANFTPF--------------PDEWTVEDKVLF 143
G N E AL L K DV +L L P D+WT ++ LF
Sbjct: 839 PGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLF 898
Query: 144 EQAFGFHGKCFQRIQQMLPDKLIPSLVKYYYSWKK---------TRSRTSVMDRQARRLG 194
+A + K F +Q+M+ K + V+YYY+WKK TR + D
Sbjct: 899 NKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEE 958
Query: 195 GRKDKEDSDELEEGRGGVSEGEPD-PADPKREPLP 228
++E+ ++ EE R E E + P P+ P+P
Sbjct: 959 EELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVP 993
Score = 43.9 bits (102), Expect = 4e-04
Identities = 58/266 (21%), Positives = 107/266 (40%), Gaps = 49/266 (18%)
Query: 236 PGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGS------PDLANLTLRGLDS 289
PGPG++ V V + LR + P+ +S + P+L N L+
Sbjct: 768 PGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVE 827
Query: 290 QLISL-------------KRQVQSMKQTNSSLRQALEGGI--DPLR---PPEANTKF--N 329
L++L + + S+ + + ALE + P+R P AN + +
Sbjct: 828 NLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGS 887
Query: 330 SRWTTDEQLLAVQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRR--------RFNLEE 381
+WT+ E+ L +A+ Y KDF + +++ +KT+ Q ++ ++++ R L E
Sbjct: 888 DKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAE 947
Query: 382 VLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPP 441
++ + ++ +EE P E+D + VP+S P P P
Sbjct: 948 IIDDCVTSEE-----EEELEEEEEEDP-------EEDRKSTKEEESEVPKSPEPPPVPVL 995
Query: 442 PPTSLSQPPPLLRPPLPTAPTLLRQP 467
PT + PPL P+ + P
Sbjct: 996 APT---EGPPLQALGQPSGSFICEMP 1018
Score = 38.5 bits (88), Expect = 0.015
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 8/65 (12%)
Query: 430 PRSVPPAPPPPPPPTSLSQPP------PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPN 483
P+ PP PPPPPPP PP P++ P + P L P P QG AP+
Sbjct: 554 PQPQPPLPPPPPPPPPPQLPPEAESLTPMVMP--VSVPVKLLPPKPSSQGFTNSTVAAPS 611
Query: 484 QPPPP 488
P
Sbjct: 612 ARDKP 616
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 464 LRQPPPLQQG---RFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPA 520
+R P L+Q + L P+ P PPPP P P + P P + L PP
Sbjct: 537 MRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPK 596
Query: 521 PS 522
PS
Sbjct: 597 PS 598
Score = 29.6 bits (65), Expect = 7.0
Identities = 43/166 (25%), Positives = 60/166 (36%), Gaps = 56/166 (33%)
Query: 378 NLEEVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAP 437
N+ +VL A DGAP + + +++ PAPA+ S + VP P
Sbjct: 161 NMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAI------------PSRYQQVPQQP 208
Query: 438 PP------PPPPTSLSQPP-----------PLLRPPLP-----TAPTLLRQP-------- 467
P P + Q P PL + P+ AP +L Q
Sbjct: 209 HPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQ 268
Query: 468 --PPLQQGRFLQPRLAPN--QPPPPLIRPALAAPRHSARPGPQPPP 509
PP QQ + Q R++ Q P IRP+ PQPPP
Sbjct: 269 YYPPQQQQQAGQQRISMQEIQTQPQQIRPS----------QPQPPP 304
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 63.2 bits (152), Expect = 6e-10
Identities = 41/103 (39%), Positives = 44/103 (42%), Gaps = 13/103 (12%)
Query: 430 PRSVPPAPPPPP-PPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQP-------RLA 481
P PP PPPPP PP S PPP + PP P P PPP F P
Sbjct: 475 PHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYP----PPPPTYNPNFPPPPPRLPPTHAV 530
Query: 482 PNQPPPPLIRPALAAPRHSARPGPQPP-PTLIGAPLEPPAPSL 523
P PPP L P + P + PG QPP P I P PP L
Sbjct: 531 PPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGL 573
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/141 (26%), Positives = 50/141 (35%), Gaps = 25/141 (17%)
Query: 390 QDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPP-------- 441
Q P P ++ + P+P +V+ V + + PPPP
Sbjct: 303 QQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH 362
Query: 442 PPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSA 501
PP + PPP +PPL A P P+ A + P + PA AP H
Sbjct: 363 PPLPPAHPPPDRKPPLAAALGEAEPPGPVD---------ATDLPKVQIPPPAHPAPVHQP 413
Query: 502 RPGPQPPPTLIGAPLEPPAPS 522
P P PP PP PS
Sbjct: 414 PPLPHRPP--------PPPPS 426
Score = 39.3 bits (90), Expect = 0.009
Identities = 35/139 (25%), Positives = 48/139 (34%), Gaps = 29/139 (20%)
Query: 412 PALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRP----PLPTAPTLLRQ- 466
P+L+ +V S S P P P Q P +P P P++P +++
Sbjct: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRA 336
Query: 467 ---------------PPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGP------ 505
PP + + P L P PPP P AA + PGP
Sbjct: 337 VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDL 396
Query: 506 ---QPPPTLIGAPLEPPAP 521
Q PP AP+ P P
Sbjct: 397 PKVQIPPPAHPAPVHQPPP 415
Score = 37.7 bits (86), Expect = 0.026
Identities = 35/123 (28%), Positives = 40/123 (32%), Gaps = 37/123 (30%)
Query: 438 PPPPPPTSLSQPPPLL-RPPLP------------------------------TAPTLLRQ 466
PPP P + QPPPL RPP P P+
Sbjct: 402 PPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461
Query: 467 PPPLQQGRFL--QPRLAPNQPPPPLIRPALAAPRHSA----RPGPQPPPTLIGAPLEPPA 520
PP L P + P PPPP + P A+ A PG PPP PP
Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPP 521
Query: 521 PSL 523
P L
Sbjct: 522 PRL 524
Score = 32.7 bits (73), Expect = 0.83
Identities = 27/101 (26%), Positives = 37/101 (36%), Gaps = 19/101 (18%)
Query: 434 PPA--PPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPP---- 487
PP+ P P P SQP P P +Q P Q + QP P +P P
Sbjct: 276 PPSLQPTPQVPQVQQSQPSQSSEPSQP------QQKDPQQPAQQQQPAQQPKKPSPQPSS 329
Query: 488 --PLIRPALAAPRHSARPGPQPPPTL-----IGAPLEPPAP 521
+ R + +P+ + PPP + PL P P
Sbjct: 330 PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370
Score = 30.0 bits (66), Expect = 5.4
Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 22/80 (27%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPP--PPTSLSQP-- 449
PG P P P P P L +VPP PPP PP S P
Sbjct: 504 PGYPPPPPTYNPNFPPPPPRLPPT-------------HAVPPHPPPGLGLPPASYPPPAV 550
Query: 450 PPLLRPPLPTAPTLLRQPPP 469
PP +PP+P P + PPP
Sbjct: 551 PPGGQPPVP--PPI---PPP 565
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 62.8 bits (151), Expect = 7e-10
Identities = 46/139 (33%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 394 PGAPVPMEEARRGAPLPAPAL-----EEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQ 448
P AP P+ P PA ++ + + P VPP+PP P + L++
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 449 PPPLLRPPLPTAPTLLRQPPPLQ---QGRFLQPRLAPNQP---PPPLIRPALAAPRHSAR 502
PPP P L T P PP Q F P P PPP P LAAP
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 503 PGPQPPPTLIGAPLEPPAP 521
P P PTL AP PP P
Sbjct: 844 PSPPASPTL-QAPRRPPTP 861
Score = 62.4 bits (150), Expect = 1e-09
Identities = 47/129 (36%), Positives = 57/129 (44%), Gaps = 23/129 (17%)
Query: 396 APVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAP---PPPPPPTSLSQPPPL 452
AP P++ A APL P LE P PP+P PPP P+S++ PPP
Sbjct: 542 APPPLQTA--SAPLTTPHLETPP------CPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLI 512
P L + PPLQ P L+P PPP P LA P A P P P L
Sbjct: 594 APPALAS--------PPLQ--GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL- 642
Query: 513 GAPLEPPAP 521
+PL P+P
Sbjct: 643 -SPLATPSP 650
Score = 61.6 bits (148), Expect = 2e-09
Identities = 48/142 (33%), Positives = 54/142 (38%), Gaps = 14/142 (9%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVP---PAPPPPPPPTSLSQP 449
AP +P P P+P V + S P S P P PP PP S S
Sbjct: 632 APPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 450 PPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAP---------RHS 500
PP PP AP L P P P Q PPPL P L P S
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 501 ARPGPQPPPTLIGAPLE-PPAP 521
A P P+ PP L PL+ PP+P
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSP 772
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 16/131 (12%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEV--QITSVSTSVPRSVPPAPPPPPPPTSLSQ-PP 450
P PV + +P +P+ + + + VP S P +PP P T Q PP
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 451 PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPT 510
PL PPL P+ PP P ++P+ PPP + P LAAP + P PP +
Sbjct: 729 PLAAPPLQVPPS----PP-------ASPPMSPSATPPPRVPPLLAAP--PLQVPPSPPAS 775
Query: 511 LIGAPLEPPAP 521
L +PL P P
Sbjct: 776 LPMSPLAKPPP 786
Score = 56.2 bits (134), Expect = 7e-08
Identities = 41/120 (34%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
+P A +PM + P PAL + S S P P +P P + L+ PPP
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP- 829
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPR--HSARPGPQPPPT 510
PP+ AP LL+ PP LQ AP +PP P +++ PR + PGP PPP+
Sbjct: 830 QAPPVLAAP-LLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
Score = 51.2 bits (121), Expect = 2e-06
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 32/155 (20%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPP-APPP----PPPPTS-LS 447
P P P +PL P E +S++T P++ P A PP P PP S L+
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETP-----SSIATPPPQAPPALASPPLQGLPSPPLSPLA 615
Query: 448 QPPP-----LLRPPLPTAPTLLRQPP--PLQQGRFLQPRL-------APNQPPP------ 487
PPP L PPL P+ PP PL P AP PPP
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Query: 488 PLIRPALAAPRHSARPGPQPPPTLIGAPLE-PPAP 521
P PA SA P Q PP+L PL+ PP+P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/142 (30%), Positives = 56/142 (39%), Gaps = 13/142 (9%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDD--------EVQITSVSTSVPRSVPPAPPPPPPPT 444
AP +P+ + + L +P L+ + Q + S S P S PP PP P
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 445 SLSQPPPLLRPPLPTAPTLLRQP---PPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSA 501
SL PP L+ L A + L P PLQ L +P P LI P L A
Sbjct: 462 SLPASPP-LQTSLSPAVSPLSSPLTIHPLQALSSLASH-SPQAPLSSLIMPPLETQSSLA 519
Query: 502 RPGPQPPPTLIGAPLEPPAPSL 523
P Q PP + P PSL
Sbjct: 520 PPSLQTPPASLTTPPLENLPSL 541
Score = 46.6 bits (109), Expect = 6e-05
Identities = 40/116 (34%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 411 APALEEDDEVQITSVSTSVPRSVPPAPPP---PPPPTSLSQPPPLLRPPLPTAPTLLRQP 467
APAL + + S S ++ P PP P P +L PPL P LP AP P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP-LPLAPPSPSAP 351
Query: 468 PPLQQGRFLQPRLAPNQPPPPLIRPALAAPRH-SARPGPQPPPTLIGAPLE-PPAP 521
P LQ P P+Q PP + P + AP P Q P +L L+ PP+P
Sbjct: 352 PSLQTLPS-PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Score = 45.8 bits (107), Expect = 9e-05
Identities = 46/155 (29%), Positives = 62/155 (40%), Gaps = 22/155 (14%)
Query: 381 EVLQEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPP 440
+ L + AP + + M + L P+L+ S++T ++P PPP
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP----ASLTTPPLENLPSLAPPP 545
Query: 441 PPPTSLSQPPPLLRPPLPTAPTLLRQPP-PLQQGRFLQPRLAPNQ--PPPPLIRPALAAP 497
S P L P AP L+ PP PL P P+ PPP PALA+P
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT----PPPETPSSIATPPPQAPPALASP 601
Query: 498 ----------RHSARPGPQPPPTLIGAPLE-PPAP 521
A P PQ PP L PL+ PP+P
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/126 (30%), Positives = 43/126 (34%), Gaps = 13/126 (10%)
Query: 394 PGAPV-PMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
P P P +A R P P P S S PR P PPPP S S L
Sbjct: 844 PSPPASPTLQAPRRPPTPGP-----------DTSVSGPRLTLALAPGPPPPPSRSPSSTL 892
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPTLI 512
P L + P +G P PPP A P +R GP PP
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFR 951
Query: 513 GAPLEP 518
GAP P
Sbjct: 952 GAPGAP 957
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 34/159 (21%)
Query: 392 GAPGAPVPMEEARRGAPLPA---PALEEDDEVQITSVSTSVPRSV-----PPAPPPPPPP 443
G PVP + PLPA P+ + + S S P S+ PPA PP P
Sbjct: 311 GTKARPVPPPD-NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 444 TSLSQPP-----------PLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQP------- 485
S++ PP P+ P T+P+L P PL LQ + P
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS-LQATTSLGSPTLQATHS 428
Query: 486 ----PPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPPA 520
P + +L +P A P PP + APL PA
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPP--LQAPLSLPA 465
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/131 (32%), Positives = 51/131 (38%), Gaps = 15/131 (11%)
Query: 403 ARRGAPLPAPALEEDDEVQITSVST---SVPRSVPPAPPPPPPPTSLSQPPP----LLRP 455
A R P L+ ++S +T S RS P A P P SQP P LRP
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 456 PLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQP----PPTL 511
P T P R+ G LA P RP + P ++A P P PP
Sbjct: 283 PQVTPP---RKDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPLPATLPPSPPLA 338
Query: 512 IGAPLEPPAPS 522
PL PP+PS
Sbjct: 339 TPLPLAPPSPS 349
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 61.2 bits (147), Expect = 2e-09
Identities = 54/149 (36%), Positives = 60/149 (40%), Gaps = 34/149 (22%)
Query: 397 PVPMEEARRGAPLPAPALEEDDEVQITSV-STSVPR------SVPPAPPPPP--PPTSLS 447
P P E ++ P A A E D Q S+ S PR S PP PPPPP P +S
Sbjct: 379 PKPSVEGQQ--PAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAE 436
Query: 448 QPPPLLRPPLPTA-----PTLLRQPPPLQQGRFLQPRLAPNQPP----------PPLIRP 492
PPP PPLP+ PT PPPL + P P PP PP P
Sbjct: 437 PPPPPPPPPLPSVGAKALPTA-PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLP 495
Query: 493 ALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
L P P PPP L G PP P
Sbjct: 496 GLGCP-------PPPPPLLPGMGWGPPPP 517
Score = 56.2 bits (134), Expect = 7e-08
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 371 VSYRRRFNLEEVLQEWEAEQDGA---PGAPVPMEEARRGAPLPAPALEEDDEVQITSVST 427
V + + ++ +V Q EQ + P P P+ P P P + SV
Sbjct: 397 VDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP-----PPPLPSVGA 451
Query: 428 SVPRSVPPAPPPPPPPT--SLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQP 485
+++P APPPPP P +++ P P L PPLP + L PPP G P P
Sbjct: 452 ---KALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPP------P 502
Query: 486 PPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPP 519
PPPL+ P P PPP L+ PP
Sbjct: 503 PPPLLPGMGWGP-------PPPPPPLLPCTCSPP 529
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 61.2 bits (147), Expect = 2e-09
Identities = 54/149 (36%), Positives = 60/149 (40%), Gaps = 34/149 (22%)
Query: 397 PVPMEEARRGAPLPAPALEEDDEVQITSV-STSVPR------SVPPAPPPPP--PPTSLS 447
P P E ++ P A A E D Q S+ S PR S PP PPPPP P +S
Sbjct: 379 PKPSVEGQQ--PAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAE 436
Query: 448 QPPPLLRPPLPTA-----PTLLRQPPPLQQGRFLQPRLAPNQPP----------PPLIRP 492
PPP PPLP+ PT PPPL + P P PP PP P
Sbjct: 437 PPPPPPPPPLPSVGAKALPTA-PPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLP 495
Query: 493 ALAAPRHSARPGPQPPPTLIGAPLEPPAP 521
L P P PPP L G PP P
Sbjct: 496 GLGCP-------PPPPPLLPGMGWGPPPP 517
Score = 56.2 bits (134), Expect = 7e-08
Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 26/154 (16%)
Query: 371 VSYRRRFNLEEVLQEWEAEQDGA---PGAPVPMEEARRGAPLPAPALEEDDEVQITSVST 427
V + + ++ +V Q EQ + P P P+ P P P + SV
Sbjct: 397 VDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP-----PPPLPSVGA 451
Query: 428 SVPRSVPPAPPPPPPPT--SLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQP 485
+++P APPPPP P +++ P P L PPLP + L PPP G P P
Sbjct: 452 ---KALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPP------P 502
Query: 486 PPPLIRPALAAPRHSARPGPQPPPTLIGAPLEPP 519
PPPL+ P P PPP L+ PP
Sbjct: 503 PPPLLPGMGWGP-------PPPPPPLLPCTCSPP 529
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/118 (36%), Positives = 54/118 (45%), Gaps = 24/118 (20%)
Query: 422 ITSVSTSVPRSVPPA---------PPPPPPPTSLSQPPPLLR------PPLPTAPTLLRQ 466
+ +V + R PP PPPPPPP + PPP R PP APT
Sbjct: 265 VEAVKNELRRQAPP-PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPP 323
Query: 467 PPPLQQGRFLQPRLAPNQ--PPPPLIRPALAAPRHSARPGPQPPPTLIG-APLEPPAP 521
PPP + P PN+ PPPP PAL P + P PPP+++G P+ PP P
Sbjct: 324 PPPPSRPSVAVPPPPPNRMYPPPP---PAL--PSSAPSGPPPPPPSVLGVGPVAPPPP 376
Score = 60.1 bits (144), Expect = 5e-09
Identities = 47/132 (35%), Positives = 54/132 (40%), Gaps = 19/132 (14%)
Query: 396 APVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPP--PTSLSQPPPLL 453
AP P +R G P P P S P APPPPP PT+ PPP
Sbjct: 276 APPPPPPSRGGPPPPPPPPHN-------SGPPPPPARGRGAPPPPPSRAPTAAPPPPPPS 328
Query: 454 RPPL---PTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQPPPT 510
RP + P P + PPP P AP+ PPPP P++ A P P PPP
Sbjct: 329 RPSVAVPPPPPNRMYPPPPPAL-----PSSAPSGPPPP--PPSVLGVGPVAPPPPPPPPP 381
Query: 511 LIGAPLEPPAPS 522
G P P PS
Sbjct: 382 PPGPPPPPGLPS 393
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/111 (38%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 418 DEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFL- 476
D ++ T +V + PPPPPP S PPP PP + P PPP +GR
Sbjct: 257 DFIEKTGGVEAVKNELRRQAPPPPPP-SRGGPPPPPPPPHNSGP-----PPPPARGRGAP 310
Query: 477 --QPRLAPN--QPPPPLIRPALAAPRHSA-RPGPQPPPTL-IGAPLEPPAP 521
P AP PPPP RP++A P R P PPP L AP PP P
Sbjct: 311 PPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPP 361
Score = 36.6 bits (83), Expect = 0.057
Identities = 28/79 (35%), Positives = 29/79 (36%), Gaps = 23/79 (29%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPP-PTSLS--QPP 450
P VP R P P PAL P S P PPPPPP + PP
Sbjct: 330 PSVAVPPPPPNRMYPPPPPAL---------------PSSAPSGPPPPPPSVLGVGPVAPP 374
Query: 451 PLLRPPLPTAPTLLRQPPP 469
P PP P P PPP
Sbjct: 375 PPPPPPPPPGP-----PPP 388
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/155 (32%), Positives = 63/155 (40%), Gaps = 25/155 (16%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS---VPPAPPPPPPP------- 443
P P PM A P+P ++ S + R+ V P PPPPPPP
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
Query: 444 -----TSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQGRFLQPRLAPNQPP--PPLIRP- 492
+ S PPP + PP P T L+ PPP + L P PP PPL++P
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 493 ---ALAAPRHSARP-GPQPPPTLIGAPLEPPAPSL 523
A AAP P P P + G P PP P L
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/148 (33%), Positives = 58/148 (39%), Gaps = 35/148 (23%)
Query: 408 PLPAPALEEDDEVQITSVSTSVPRSVPPAPPP---------PPPPTSLSQPPPLLRP-PL 457
P P P+ ++ + ST P PP PPP PPPP L P +L P P
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
Query: 458 PTAPTLLRQPPP---------------LQQGRF--LQPRLAPNQPPPPLIRP-------A 493
P AP L++ PP L QG L P P PPP IRP A
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTA 447
Query: 494 LAAPRHSARPGPQPPPTLIGAPLEPPAP 521
LA P P P P PL PP+P
Sbjct: 448 LAHPPSGLHPTPSTAPG-PHVPLMPPSP 474
Score = 43.1 bits (100), Expect = 6e-04
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 23/122 (18%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
AP P R AP+ + V + + + +PP PPPPP PPP
Sbjct: 390 APPLVQPSPPVARAAPVC-------ETVPVHPLPQGEVQGLPPPPPPPP------LPPPG 436
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQP---PP 509
+RP P T L PP G P AP P PL+ P +P P +P P
Sbjct: 437 IRPSSPVTVTALAHPP---SGLHPTPSTAPG-PHVPLMPP---SPPSQVIPASEPKRHPS 489
Query: 510 TL 511
TL
Sbjct: 490 TL 491
Score = 42.7 bits (99), Expect = 8e-04
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 433 VPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLL-RQPPPLQQGR---FLQPRLAPNQPPPP 488
V P PPPPPP + + + +A L+ +P GR F+ P P PPPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP--TPPPPPPP 330
Query: 489 L--------IRPAL-AAPRHSARPGPQPPPTLIGAPLEPPAPS 522
L +R ++ + P P P PP T + AP PP P+
Sbjct: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
+ E G P P P PLP P + V +T+++ PP+ P P T+
Sbjct: 417 QGEVQGLPPPPPP-------PPLPPPGIRPSSPVTVTALAH------PPSGLHPTPSTAP 463
Query: 447 SQPPPLLRPPLPTAPTLLRQPP 468
PL+ PP P + + P
Sbjct: 464 GPHVPLM-PPSPPSQVIPASEP 484
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/155 (32%), Positives = 63/155 (40%), Gaps = 25/155 (16%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS---VPPAPPPPPPP------- 443
P P PM A P+P ++ S + R+ V P PPPPPPP
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
Query: 444 -----TSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQGRFLQPRLAPNQPP--PPLIRP- 492
+ S PPP + PP P T L+ PPP + L P PP PPL++P
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 493 ---ALAAPRHSARP-GPQPPPTLIGAPLEPPAPSL 523
A AAP P P P + G P PP P L
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/148 (33%), Positives = 58/148 (39%), Gaps = 35/148 (23%)
Query: 408 PLPAPALEEDDEVQITSVSTSVPRSVPPAPPP---------PPPPTSLSQPPPLLRP-PL 457
P P P+ ++ + ST P PP PPP PPPP L P +L P P
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
Query: 458 PTAPTLLRQPPP---------------LQQGRF--LQPRLAPNQPPPPLIRP-------A 493
P AP L++ PP L QG L P P PPP IRP A
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTA 447
Query: 494 LAAPRHSARPGPQPPPTLIGAPLEPPAP 521
LA P P P P PL PP+P
Sbjct: 448 LAHPPSGLHPTPSTAPG-PHVPLMPPSP 474
Score = 43.1 bits (100), Expect = 6e-04
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 23/122 (18%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
AP P R AP+ + V + + + +PP PPPPP PPP
Sbjct: 390 APPLVQPSPPVARAAPVC-------ETVPVHPLPQGEVQGLPPPPPPPP------LPPPG 436
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQP---PP 509
+RP P T L PP G P AP P PL+ P +P P +P P
Sbjct: 437 IRPSSPVTVTALAHPP---SGLHPTPSTAPG-PHVPLMPP---SPPSQVIPASEPKRHPS 489
Query: 510 TL 511
TL
Sbjct: 490 TL 491
Score = 42.7 bits (99), Expect = 8e-04
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 433 VPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLL-RQPPPLQQGR---FLQPRLAPNQPPPP 488
V P PPPPPP + + + +A L+ +P GR F+ P P PPPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP--TPPPPPPP 330
Query: 489 L--------IRPAL-AAPRHSARPGPQPPPTLIGAPLEPPAPS 522
L +R ++ + P P P PP T + AP PP P+
Sbjct: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
+ E G P P P PLP P + V +T+++ PP+ P P T+
Sbjct: 417 QGEVQGLPPPPPP-------PPLPPPGIRPSSPVTVTALAH------PPSGLHPTPSTAP 463
Query: 447 SQPPPLLRPPLPTAPTLLRQPP 468
PL+ PP P + + P
Sbjct: 464 GPHVPLM-PPSPPSQVIPASEP 484
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/155 (32%), Positives = 63/155 (40%), Gaps = 25/155 (16%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS---VPPAPPPPPPP------- 443
P P PM A P+P ++ S + R+ V P PPPPPPP
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
Query: 444 -----TSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQGRFLQPRLAPNQPP--PPLIRP- 492
+ S PPP + PP P T L+ PPP + L P PP PPL++P
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 493 ---ALAAPRHSARP-GPQPPPTLIGAPLEPPAPSL 523
A AAP P P P + G P PP P L
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/148 (33%), Positives = 58/148 (39%), Gaps = 35/148 (23%)
Query: 408 PLPAPALEEDDEVQITSVSTSVPRSVPPAPPP---------PPPPTSLSQPPPLLRP-PL 457
P P P+ ++ + ST P PP PPP PPPP L P +L P P
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
Query: 458 PTAPTLLRQPPP---------------LQQGRF--LQPRLAPNQPPPPLIRP-------A 493
P AP L++ PP L QG L P P PPP IRP A
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTA 447
Query: 494 LAAPRHSARPGPQPPPTLIGAPLEPPAP 521
LA P P P P PL PP+P
Sbjct: 448 LAHPPSGLHPTPSTAPG-PHVPLMPPSP 474
Score = 43.1 bits (100), Expect = 6e-04
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 23/122 (18%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
AP P R AP+ + V + + + +PP PPPPP PPP
Sbjct: 390 APPLVQPSPPVARAAPVC-------ETVPVHPLPQGEVQGLPPPPPPPP------LPPPG 436
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQP---PP 509
+RP P T L PP G P AP P PL+ P +P P +P P
Sbjct: 437 IRPSSPVTVTALAHPP---SGLHPTPSTAPG-PHVPLMPP---SPPSQVIPASEPKRHPS 489
Query: 510 TL 511
TL
Sbjct: 490 TL 491
Score = 42.7 bits (99), Expect = 8e-04
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 433 VPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLL-RQPPPLQQGR---FLQPRLAPNQPPPP 488
V P PPPPPP + + + +A L+ +P GR F+ P P PPPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP--TPPPPPPP 330
Query: 489 L--------IRPAL-AAPRHSARPGPQPPPTLIGAPLEPPAPS 522
L +R ++ + P P P PP T + AP PP P+
Sbjct: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
+ E G P P P PLP P + V +T+++ PP+ P P T+
Sbjct: 417 QGEVQGLPPPPPP-------PPLPPPGIRPSSPVTVTALAH------PPSGLHPTPSTAP 463
Query: 447 SQPPPLLRPPLPTAPTLLRQPP 468
PL+ PP P + + P
Sbjct: 464 GPHVPLM-PPSPPSQVIPASEP 484
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 59.7 bits (143), Expect = 6e-09
Identities = 51/155 (32%), Positives = 63/155 (40%), Gaps = 25/155 (16%)
Query: 394 PGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRS---VPPAPPPPPPP------- 443
P P PM A P+P ++ S + R+ V P PPPPPPP
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALST 337
Query: 444 -----TSLSQPPPLLRPPLPTAPTLLRQ---PPPLQQGRFLQPRLAPNQPP--PPLIRP- 492
+ S PPP + PP P T L+ PPP + L P PP PPL++P
Sbjct: 338 SSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Query: 493 ---ALAAPRHSARP-GPQPPPTLIGAPLEPPAPSL 523
A AAP P P P + G P PP P L
Sbjct: 398 PPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPL 432
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/148 (33%), Positives = 58/148 (39%), Gaps = 35/148 (23%)
Query: 408 PLPAPALEEDDEVQITSVSTSVPRSVPPAPPP---------PPPPTSLSQPPPLLRP-PL 457
P P P+ ++ + ST P PP PPP PPPP L P +L P P
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPP 387
Query: 458 PTAPTLLRQPPP---------------LQQGRF--LQPRLAPNQPPPPLIRP-------A 493
P AP L++ PP L QG L P P PPP IRP A
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTA 447
Query: 494 LAAPRHSARPGPQPPPTLIGAPLEPPAP 521
LA P P P P PL PP+P
Sbjct: 448 LAHPPSGLHPTPSTAPG-PHVPLMPPSP 474
Score = 43.1 bits (100), Expect = 6e-04
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 23/122 (18%)
Query: 393 APGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSLSQPPPL 452
AP P R AP+ + V + + + +PP PPPPP PPP
Sbjct: 390 APPLVQPSPPVARAAPVC-------ETVPVHPLPQGEVQGLPPPPPPPP------LPPPG 436
Query: 453 LRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSARPGPQP---PP 509
+RP P T L PP G P AP P PL+ P +P P +P P
Sbjct: 437 IRPSSPVTVTALAHPP---SGLHPTPSTAPG-PHVPLMPP---SPPSQVIPASEPKRHPS 489
Query: 510 TL 511
TL
Sbjct: 490 TL 491
Score = 42.7 bits (99), Expect = 8e-04
Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 433 VPPAPPPPPPPTSLSQPPPLLRPPLPTAPTLL-RQPPPLQQGR---FLQPRLAPNQPPPP 488
V P PPPPPP + + + +A L+ +P GR F+ P P PPPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP--TPPPPPPP 330
Query: 489 L--------IRPAL-AAPRHSARPGPQPPPTLIGAPLEPPAPS 522
L +R ++ + P P P PP T + AP PP P+
Sbjct: 331 LPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPA 373
Score = 30.4 bits (67), Expect = 4.1
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 387 EAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPPTSL 446
+ E G P P P PLP P + V +T+++ PP+ P P T+
Sbjct: 417 QGEVQGLPPPPPP-------PPLPPPGIRPSSPVTVTALAH------PPSGLHPTPSTAP 463
Query: 447 SQPPPLLRPPLPTAPTLLRQPP 468
PL+ PP P + + P
Sbjct: 464 GPHVPLM-PPSPPSQVIPASEP 484
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,480,421
Number of Sequences: 37866
Number of extensions: 2014584
Number of successful extensions: 39856
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 838
Number of HSP's successfully gapped in prelim test: 1352
Number of HSP's that attempted gapping in prelim test: 13621
Number of HSP's gapped (non-prelim): 12012
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.