Search of human proteins with 27734727

Search of human proteins with 27734727

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27734727 INO80 complex subunit E [Homo sapiens]
         (244 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27734727 INO80 complex subunit E [Homo sapiens]                    499   e-141
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 51   1e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    50   2e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    50   2e-06
gi|153792074 proline rich 12 [Homo sapiens]                            47   2e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     47   2e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    46   3e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   4e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    45   6e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    45   6e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   6e-05
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    44   1e-04
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        44   1e-04
gi|47519490 reticulon 4 isoform D [Homo sapiens]                       44   2e-04
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       44   2e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    44   2e-04
gi|33356148 formin-like 1 [Homo sapiens]                               44   2e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    43   2e-04
gi|46852390 coiled-coil domain containing 6 [Homo sapiens]             43   2e-04
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    43   3e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    43   3e-04
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]              42   4e-04
gi|24431933 reticulon 4 isoform B [Homo sapiens]                       42   5e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   5e-04
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]         42   5e-04
gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]         42   5e-04
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   42   6e-04
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              42   6e-04
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    41   8e-04
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    41   8e-04

>gi|27734727 INO80 complex subunit E [Homo sapiens]
          Length = 244

 Score =  499 bits (1284), Expect = e-141
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MNGPADGEVDYKKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKSFLLDRLLQY 60
           MNGPADGEVDYKKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKSFLLDRLLQY
Sbjct: 1   MNGPADGEVDYKKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKSFLLDRLLQY 60

Query: 61  ENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPL 120
           ENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPL
Sbjct: 61  ENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPL 120

Query: 121 QASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCP 180
           QASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCP
Sbjct: 121 QASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCP 180

Query: 181 VGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDLVI 240
           VGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDLVI
Sbjct: 181 VGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDLVI 240

Query: 241 DIPE 244
           DIPE
Sbjct: 241 DIPE 244


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 60/213 (28%), Positives = 81/213 (38%), Gaps = 40/213 (18%)

Query: 12  KKKYRNLKRKLKFLIYEHECFQEELRKAQRKLLKVSRDKS------FLLDRLLQYENVDE 65
           +KK +N+K              +E+ +  R++ + S D           ++  Q ++ +E
Sbjct: 318 RKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEE 377

Query: 66  DSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGV 125
             SD  +TASS       +   S   AP     PPLG  P+P      P TG P      
Sbjct: 378 SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLP------ 431

Query: 126 PSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPL 185
           P P   +      PPF      L+ P    LR        LPR L     PP  P G P 
Sbjct: 432 PGPPPGA------PPF------LRPPGMPGLRGP------LPRLL-----PPGPPPGRP- 467

Query: 186 TFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVP 218
             PG   G   G  L P PPP+ PPP +    P
Sbjct: 468 --PGPPPGPPPG--LPPGPPPRGPPPRLPPPAP 496


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 14/140 (10%)

Query: 68  SDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPS 127
           S + A  +   +  EG P  +  P P  +  P  GG   P     PPS   PL  +G P+
Sbjct: 66  SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG----PPSPRRPLVPAG-PA 120

Query: 128 PYLSSL------ASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPV 181
           P  + L      ++    P P+       PEP+P  P +   P  P  L    GP   P 
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK---PAGPAALAARAGPGPGPG 177

Query: 182 GGPLTFPGRGSGAGVGTTLT 201
            GP   PG G  AG G   T
Sbjct: 178 PGPGPGPGPGKPAGPGAAQT 197



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 29/103 (28%), Positives = 37/103 (35%), Gaps = 14/103 (13%)

Query: 104 APSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKR 163
           AP+ S ++  P+   PL     P   + +      PPF     A   P P+   P     
Sbjct: 212 APAVSLVNNGPAALLPLPKPAAPGTVIQT------PPFVG---AAAPPAPAAPSPPAAPA 262

Query: 164 PRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPP 206
           P  P     A  PP  P    L  P  G  AG  T    +PPP
Sbjct: 263 PAAPA----AAPPPPPPAPATLARPP-GHPAGPPTAAPAVPPP 300



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 10/137 (7%)

Query: 85  PKLSDTPAPKRKRSPPLGGAPSPSSLSLPPS--TGFPLQASGVPSPYLS----SLASSRY 138
           P     PAP    + P    P+P++L+ PP    G P  A  VP P  +    S  ++  
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314

Query: 139 PPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAG--- 195
           P   +   A    +P P        P +  +    V     P    L   G  S A    
Sbjct: 315 PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV 374

Query: 196 VGTTLT-PLPPPKMPPP 211
           +G T+   LP P   PP
Sbjct: 375 IGPTMQGALPSPAAVPP 391


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 40/121 (33%), Positives = 46/121 (38%), Gaps = 17/121 (14%)

Query: 91  PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQL 150
           P P R   PP    P P   S PP    P +  G P P  S   ++  PP P    ++ +
Sbjct: 280 PPPSRGGPPP---PPPPPHNSGPPPP--PARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334

Query: 151 PEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPP 210
           P P P R      P LP       GPP          P   S  GVG    P PPP  PP
Sbjct: 335 PPPPPNRMYPPPPPALPSSAPS--GPP----------PPPPSVLGVGPVAPPPPPPPPPP 382

Query: 211 P 211
           P
Sbjct: 383 P 383



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 29/90 (32%), Positives = 33/90 (36%), Gaps = 10/90 (11%)

Query: 83  GTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFP 142
           G P    + AP     PP    PS +    PP+  +P      P P L S A S  PP P
Sbjct: 308 GAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYP-----PPPPALPSSAPSGPPPPP 362

Query: 143 SDYL-----ALQLPEPSPLRPKREKRPRLP 167
              L     A   P P P  P     P LP
Sbjct: 363 PSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/179 (28%), Positives = 68/179 (37%), Gaps = 35/179 (19%)

Query: 34   EELRKAQRKLLKVSRDKSFLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAP 93
            EEL++    L   S D+   + +     N D   S S A ++ D+    G PK + TP  
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAK-----NRDLQESISSAISALDDPPLAG-PKDTSTPD- 1420

Query: 94   KRKRSPPLGGAPSPSSLSLPPSTGFP-LQASGVPSPYLSSLASSRYPPFPSDYLALQLPE 152
                 PPL  AP+ +    PP  G P   ++G P P    L   + PP P        P+
Sbjct: 1421 ----GPPL--APAAAVPGPPPLPGLPSANSNGTPEP---PLLEEKPPPTPPP---APTPQ 1468

Query: 153  PSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPP 211
            P P  P    +P LP    +    P  P   PL                P PPP MP P
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP---------------PPPPPAMPSP 1512



 Score = 32.0 bits (71), Expect = 0.50
 Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 18/132 (13%)

Query: 93   PKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDY---LALQ 149
            P  +   P G   SPS          PL +   P   L     S +P     +    A  
Sbjct: 902  PNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961

Query: 150  LPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVG----GPLTFPGRGSGAGVGTTLTPLPP 205
              +  P  P+ E  P      K   GPP  P      GP   PGR SGAG  T    L P
Sbjct: 962  YGKAGP--PEDEGDP------KAGAGPPPGPPAYDPYGPYC-PGRASGAGPETPGLGLDP 1012

Query: 206  PKMPPPTILSTV 217
             K  PP + STV
Sbjct: 1013 NK--PPELPSTV 1022



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 45/163 (27%), Positives = 57/163 (34%), Gaps = 40/163 (24%)

Query: 104  APSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKR--- 160
            A  P+ + L P     L +S    P LS L    + P          P P P  P+R   
Sbjct: 1108 ADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCP----------PNPGPDGPRRRGR 1157

Query: 161  -------------EKRPRL-PRKLKMAVGPPDC--PVGGPLTFPGRGSGAG------VGT 198
                           RPR+ P ++    GP     P  G     GRG G G       GT
Sbjct: 1158 KPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGT 1217

Query: 199  TLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDLVID 241
             L PL P K     I  +VP+       S  DA+ G D   +D
Sbjct: 1218 RLEPLKPLK-----IKLSVPKAGEGLGTSSGDAISGTDHNSLD 1255



 Score = 31.2 bits (69), Expect = 0.86
 Identities = 27/89 (30%), Positives = 31/89 (34%), Gaps = 4/89 (4%)

Query: 82   EGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPY---LSSLASSRY 138
            E  P  +  PAP  +  PP    P   +L  PP    P  +S  P P          S  
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513

Query: 139  PPFPSDYLALQLPEPSPLRPKREKRPRLP 167
            PP P     L  P   P  P  E  P LP
Sbjct: 1514 PPPPPAAAPLAAPPEEPAAPSPED-PELP 1541



 Score = 28.1 bits (61), Expect = 7.3
 Identities = 35/120 (29%), Positives = 42/120 (35%), Gaps = 42/120 (35%)

Query: 96  KRSPPLGGAPSPSSLSLPPST-GFPLQASGVPSPYLSSLASSRYPPFPSDYLALQL---P 151
           ++SPP    P P++ S  P+  G  L+A G   P +        PP P   L   L   P
Sbjct: 761 QKSPP---PPPPTAQSTQPTPHGLLLEAGGPDLPLV-------LPPPPPQLLPSVLSHAP 810

Query: 152 EPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPP 211
            PSP   K                     VG  L  P    GA       P PPP  PPP
Sbjct: 811 SPSPSASK---------------------VGVHLLEPATRDGA-------PQPPPPPPPP 842



 Score = 27.7 bits (60), Expect = 9.5
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 5/68 (7%)

Query: 165 RLPRKLKMAVGPPDCPVGGPLTFPGRGSGAG-VGTTLTPLPPPKMPPPTILST--VPRQM 221
           RL  K K      + P G   +    G+GA  +G  L   PPP  PPPT  ST   P  +
Sbjct: 724 RLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP--PPPTAQSTQPTPHGL 781

Query: 222 FSDAGSGD 229
             +AG  D
Sbjct: 782 LLEAGGPD 789


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 17/126 (13%)

Query: 93  PKRKRSPPLG-----GAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLA 147
           P+R  +PP       GAP+ ++ + PP T  P      P P   + A+    P  +   A
Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRAAAAAA 156

Query: 148 LQLPEPSPLRPKREKRPRLPRKLKMAVGPPDC---PVGGPLTFPGRGSGAGVGTTLTPLP 204
              P P P +P     PR  R   +A  PP     P   P   P R     V     PLP
Sbjct: 157 TAPPSPGPAQPG----PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP 212

Query: 205 PPKMPP 210
           PP  PP
Sbjct: 213 PPPQPP 218


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 51/160 (31%), Positives = 58/160 (36%), Gaps = 7/160 (4%)

Query: 64  DEDSSDSDATASSD-NSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQA 122
           D  S  SD    SD  S     P LSD P+P           PS S +  PPS   P   
Sbjct: 197 DVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPS-DVPSLL 255

Query: 123 SGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVG 182
           SGVPSP       S  P   SD  +L    PS L         +P  L     PP     
Sbjct: 256 SGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPS 315

Query: 183 GPLTFPGRGSGAGVGTTLTPLPPPKMPPP----TILSTVP 218
            P   P   SG     +  P PP  +P P     +LS VP
Sbjct: 316 PPSDIP-LLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVP 354



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 19/153 (12%)

Query: 84  TPKLSDTPAPKRKRSPPLGGAPS-PSSLSLPPS------TGFPLQASGVPSPYLSSLAS- 135
           +P LS  P+P       L G PS PS +S PPS      +  P   SGVPSP  S + S 
Sbjct: 108 SPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSP-PSDVPSP 166

Query: 136 -SRYPPFPSDYLALQLPEPSP---LRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRG 191
            S  P  PSD  +L    PSP   +       P  P  + +    P  P   PL      
Sbjct: 167 PSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPS 226

Query: 192 SGAGVGT------TLTPLPPPKMPPPTILSTVP 218
             + V +      +L+ +P P    P++LS VP
Sbjct: 227 PPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVP 259



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 48/152 (31%), Positives = 56/152 (36%), Gaps = 7/152 (4%)

Query: 68  SDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPS 127
           SD  +  S   S     P LS  P+P       L G PSP S   PPS   P   S VPS
Sbjct: 222 SDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPS-DVPSLLSDVPS 280

Query: 128 -PYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLT 186
            P       S  P  PSD  +L    PSP        P  P  + +  G P  P   P  
Sbjct: 281 LPSDVPSLLSGVPSPPSDVPSLLSDVPSP----PSDVPSPPSDIPLLSGVPSPPSDVPSP 336

Query: 187 FPGRGSGAGVGTTLTPLPPPKMPPPTILSTVP 218
                S       L+ +P P    P +LS VP
Sbjct: 337 PSDVPSPPSDVPLLSGVPSPLSDVP-LLSGVP 367



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 53/168 (31%), Positives = 67/168 (39%), Gaps = 23/168 (13%)

Query: 68  SDSDATASSDNSETEGTPKL-SDTPAPKRK-RSPP-----LGGAPSP-SSLSLPPS---- 115
           SD  +  S   S     P L SD P+P     SPP     L G PSP S +  PPS    
Sbjct: 283 SDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPS 342

Query: 116 --TGFPLQASGVPSPYLSSLASSRYPPFPSDYLA-------LQLPEPSPLRPKREKRPRL 166
             +  PL  SGVPSP       S  P  PSD  +       L +   S + P R   P L
Sbjct: 343 PPSDVPL-LSGVPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPSL 401

Query: 167 PRKL-KMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTI 213
              +  +  G P  P G P    G    +GV +  + +P P   P T+
Sbjct: 402 LSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPSPSGVPITL 449



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 45/146 (30%), Positives = 54/146 (36%), Gaps = 26/146 (17%)

Query: 87  LSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLAS--SRYPPFPSD 144
           LSD P+       P    PSP S    P +  P   SGVPSP  S + S  S  P  PSD
Sbjct: 146 LSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSP-PSDVPSPPSDVPSPPSD 204

Query: 145 Y-LALQLPEP-------SPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGV 196
             L   +P P       S +       P LP  +    G P  P   P    G       
Sbjct: 205 VPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSG------- 257

Query: 197 GTTLTPLPPPKMPP----PTILSTVP 218
                P PP  + P    P++LS VP
Sbjct: 258 ----VPSPPSDISPPSDVPSLLSDVP 279


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 44/149 (29%), Positives = 61/149 (40%), Gaps = 14/149 (9%)

Query: 72  ATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVP--SPY 129
           AT  S    +   P L   P+P    SPP+  + +P   + PP    PLQ    P  SP 
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746

Query: 130 LSSLAS--SRYPPF---PSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGP 184
           +S  A+   R PP    P   +    P   P+ P  +  P+ P  L  A  P       P
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL--ATPPLQALPSPP 804

Query: 185 LTFPGRGS-GAGVGTTLTPL--PPPKMPP 210
            +FPG+          ++PL  PPP+ PP
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPP 833



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 25/147 (17%)

Query: 73  TASSDNSETEGTPKLSDTPAPKRKRSPPLGGA-PSPSSLSLPPSTGFPLQASGVPSPYLS 131
           +++S++S TE        P+P  +R P  GG    P+S SL  S+  PL +     P  S
Sbjct: 210 SSASEHSTTE--------PSPAARRRPSAGGGLQRPASRSLS-SSATPLSSPARSGP--S 258

Query: 132 SLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRG 191
           +  + R P  PS       P+P  L+  R  +   PRK          P  GPL+     
Sbjct: 259 ARGTPRAPAHPSQ------PKPKGLQALRPPQVTPPRK-------DAAPALGPLSSSPLA 305

Query: 192 SGAGVGTTLTPLPPPKMPPPTILSTVP 218
           + +  GT   P+PPP      + +T+P
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLP 332



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 55/160 (34%), Positives = 64/160 (40%), Gaps = 27/160 (16%)

Query: 84  TPKLSDTP---APKRKRSPPLGGAPSP--SSLSLPPSTG------FPLQASGVP--SPYL 130
           TP    TP   AP    SPPL G PSP  S L+ PP          PLQA   P  SP L
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642

Query: 131 SSLASSRYPPFPSDYLALQL------PEPSPLRPKREKRPRLPRKLKMAVGPPDCP---V 181
           S LA+    P   + LA+ L      P PSP        P  P     A  P   P    
Sbjct: 643 SPLATP--SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 182 GGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQM 221
             PL  P     A    + +  PPP+ PPP  L+  P Q+
Sbjct: 701 APPLQVP-PSPPASPPMSPSATPPPQAPPP--LAAPPLQV 737



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 40/143 (27%), Positives = 53/143 (37%), Gaps = 22/143 (15%)

Query: 82  EGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPF 141
           +  P    TP P+   S       +P +L+ PP         G+PSP LS LA+   PP 
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPP-------LQGLPSPPLSPLATP--PPQ 620

Query: 142 PSDYLAL-------QLPEPSPLRPKREKRPRLPRKLKMAV------GPPDCPVGGPLTFP 188
               LAL         P   PL P     P+ P  L + +       PP  PV  P + P
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680

Query: 189 GRGSGAGVGTTLTPLPPPKMPPP 211
                +   T  +  PP    PP
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPP 703



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 41/127 (32%), Positives = 47/127 (37%), Gaps = 24/127 (18%)

Query: 92  APKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLA---L 148
           AP    +PPL   PSP +        FP QA   PS  L     +  PP     LA   L
Sbjct: 788 APPALATPPLQALPSPPA-------SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 149 QLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKM 208
           Q+P PSP      + PR P         PD  V GP        G        P PPP  
Sbjct: 841 QVP-PSPPASPTLQAPRRP-----PTPGPDTSVSGPRLTLALAPG--------PPPPPSR 886

Query: 209 PPPTILS 215
            P + LS
Sbjct: 887 SPSSTLS 893



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 50/165 (30%), Positives = 58/165 (35%), Gaps = 57/165 (34%)

Query: 92  APKRKRSPPLGGAPSPSSLSLP------------------PSTGFPLQ-----ASGVPSP 128
           +P R  S P    P  + LSLP                  P T  PLQ     AS  P  
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502

Query: 129 YLSSL-------ASSRYPPFPSDYLALQLPEPSPLRPKREKRPRL-PRKLKMAVGP---- 176
            LSSL        SS  PP      +LQ P  S   P  E  P L P  L+ A  P    
Sbjct: 503 PLSSLIMPPLETQSSLAPP------SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556

Query: 177 ----PDCPV-------GGPLTFPGRGSGAGVGTTLTPLPPPKMPP 210
               P CP          PLT P   + + + T     PPP+ PP
Sbjct: 557 HLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT-----PPPQAPP 596



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 9/144 (6%)

Query: 81  TEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYP- 139
           TE   + + +   +R  S P  G PSP+      + G  +   G+P P  S  A  R P 
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV---GLPRPAPS--ARPRPPT 202

Query: 140 --PFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVG 197
             P  S   A +     P  P   +RP     L+            PL+ P R   +  G
Sbjct: 203 EGPRKSVSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261

Query: 198 TTLTPLPPPKMPPPTILSTVPRQM 221
           T   P  P +  P  + +  P Q+
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQV 285


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 54/176 (30%), Positives = 68/176 (38%), Gaps = 22/176 (12%)

Query: 70  SDATASSDNSETEGTPK--LSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPS 127
           S ++  S+      TP   L D P P     PP+G  PS    ++PP    P Q +  P 
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPP---PPPVGNRPSIHREAVPPP---PPQNNKPPV 294

Query: 128 PYLSS-LASSRYPPFPSDYLALQLPEPSPLRPK---REKRPRLP-RKLKMAVGPPDCPVG 182
           P      ASS+ PP P        P P PL P     ++ PRLP R L ++   P     
Sbjct: 295 PSTPRPSASSQAPPPPPPP---SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP----- 346

Query: 183 GPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDL 238
            PL  PGR        +  P PP + PP       P    S  GS   AL     L
Sbjct: 347 -PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/167 (29%), Positives = 64/167 (38%), Gaps = 28/167 (16%)

Query: 91  PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQ- 149
           P P +   PP+   P PS+ S  P    P    G P    SS  +   P  P   L+L  
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343

Query: 150 ----LPEP---SPLRPKREKRPRLPRK---LKMAVGPPDCPVGG--------PLTFPGRG 191
               LP P    PL P   +RP  P +    +    PP  PV          P T P   
Sbjct: 344 STPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-PQLP 402

Query: 192 SGAGVGTTLT----PLPPPK----MPPPTILSTVPRQMFSDAGSGDD 230
           S +GV +  +    PLPP +     PPP   ST  R  F D+   D+
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 44/164 (26%), Positives = 51/164 (31%), Gaps = 44/164 (26%)

Query: 88  SDTPAPKRKRSPP----LGGAP----------------SPSSLSLPPSTGFPLQASGVP- 126
           S  P P+R R PP    +G  P                SP +   PP  G P Q S  P 
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT 218

Query: 127 -------------------SPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLP 167
                              SP  SS   S  PP P         +P P  P    RP + 
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278

Query: 168 RKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPP 211
           R+   AV PP  P       P     +       P PPP  P P
Sbjct: 279 RE---AVPPPP-PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 54/176 (30%), Positives = 68/176 (38%), Gaps = 22/176 (12%)

Query: 70  SDATASSDNSETEGTPK--LSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPS 127
           S ++  S+      TP   L D P P     PP+G  PS    ++PP    P Q +  P 
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPP---PPPVGNRPSIHREAVPPP---PPQNNKPPV 294

Query: 128 PYLSS-LASSRYPPFPSDYLALQLPEPSPLRPK---REKRPRLP-RKLKMAVGPPDCPVG 182
           P      ASS+ PP P        P P PL P     ++ PRLP R L ++   P     
Sbjct: 295 PSTPRPSASSQAPPPPPPP---SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP----- 346

Query: 183 GPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDL 238
            PL  PGR        +  P PP + PP       P    S  GS   AL     L
Sbjct: 347 -PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/167 (29%), Positives = 64/167 (38%), Gaps = 28/167 (16%)

Query: 91  PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQ- 149
           P P +   PP+   P PS+ S  P    P    G P    SS  +   P  P   L+L  
Sbjct: 284 PPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSS 343

Query: 150 ----LPEP---SPLRPKREKRPRLPRK---LKMAVGPPDCPVGG--------PLTFPGRG 191
               LP P    PL P   +RP  P +    +    PP  PV          P T P   
Sbjct: 344 STPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-PQLP 402

Query: 192 SGAGVGTTLT----PLPPPK----MPPPTILSTVPRQMFSDAGSGDD 230
           S +GV +  +    PLPP +     PPP   ST  R  F D+   D+
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 44/164 (26%), Positives = 51/164 (31%), Gaps = 44/164 (26%)

Query: 88  SDTPAPKRKRSPP----LGGAP----------------SPSSLSLPPSTGFPLQASGVP- 126
           S  P P+R R PP    +G  P                SP +   PP  G P Q S  P 
Sbjct: 159 SGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT 218

Query: 127 -------------------SPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLP 167
                              SP  SS   S  PP P         +P P  P    RP + 
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278

Query: 168 RKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPP 211
           R+   AV PP  P       P     +       P PPP  P P
Sbjct: 279 RE---AVPPPP-PQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 41/157 (26%), Positives = 64/157 (40%), Gaps = 16/157 (10%)

Query: 62  NVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLG-GAPSPSSLSLPPSTGFPL 120
           N+    S  +A+   +NS +    K  D+PA     +PP   GAP+PS+++     G  L
Sbjct: 823 NLSSPVSPVEASFLPENSLSFQGSK--DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880

Query: 121 QASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPL------RPKREKRPRLPRKLKMAV 174
                P+P + +L      PFP +  A   P+ +P        PK+ +    P+ +  + 
Sbjct: 881 PPKETPTPSVVNL------PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934

Query: 175 GPPDCPVGGPLTFPG-RGSGAGVGTTLTPLPPPKMPP 210
            P   P     T P  +G  A       P PP   PP
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 42/155 (27%), Positives = 56/155 (36%), Gaps = 36/155 (23%)

Query: 90   TPAPKRKRSPPLGGAPSPSS-LSLPPSTGFPLQASGVP----------SPYLSSLASSRY 138
            TP PK   + P    PSP   L+ PP  G P   +  P          SP  +    +  
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 139  PPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGP----------PDCPVGGPLTFP 188
            PP P   LA   P+ +P  P     P  P+       P          P  P GGP T P
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAAT--PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259

Query: 189  GRGSGAGVGTTLTPLPPPKMPPPTI---LSTVPRQ 220
             +G+            PP   PP++   L+T P +
Sbjct: 1260 PKGAPT----------PPAATPPSLKGGLATPPHK 1284



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 39/140 (27%), Positives = 48/140 (34%), Gaps = 20/140 (14%)

Query: 90   TPAPKRKRSPPLGGAPSP-SSLSLPPSTGFPLQASGVPSPYLSSLAS----------SRY 138
            TP+PK    PP    PSP   L+ PP  G P   +  P      LA+          +  
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155

Query: 139  PPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGT 198
            PP P   LA   P+ +P  P     P  P+       P   P     T P    G     
Sbjct: 1156 PPSPKGGLATPPPKGAPTTP--AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-- 1211

Query: 199  TLTPLPPPKMPPPTILSTVP 218
                 P PK  P T  +T P
Sbjct: 1212 -----PSPKGAPTTPAATPP 1226



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 10/130 (7%)

Query: 90   TPAPKRKRSPPLGGAPSPSS-LSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLAL 148
            TP+PK   + P    PSP    + PP  G P   +  P      LA+   PP        
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT---PPHKG----- 1285

Query: 149  QLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKM 208
              P P+ + P   K        K A  PP      P   PG     G  T     PP   
Sbjct: 1286 -APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344

Query: 209  PPPTILSTVP 218
              PT+ +T P
Sbjct: 1345 GTPTLPATTP 1354



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 42/146 (28%), Positives = 57/146 (39%), Gaps = 38/146 (26%)

Query: 90   TPAPKRKRSPPLG---------------GAPSPSSLSLPPSTGFPLQASGVPSPYLSSLA 134
            TP+PK   +PP                 GAP+P +++ P   G P   +  P P  +S  
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP---AATPFPKGASTP 1035

Query: 135  SSRYPPFP-SDYLALQLPE-----PSPLRPKREKRPRLPRKLKMAVGP----PDCPVGGP 184
             +  PP P     A  LP+     P+   P  +  P  P  LK A  P    P  P GGP
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP-SLKGAPTPPAATPPSPKGGP 1094

Query: 185  LTFPGRGSGAGVGTTLTPLPPPKMPP 210
             T   +G+         P+PP   PP
Sbjct: 1095 ATPSPKGA---------PMPPAATPP 1111



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 84   TPKLSD-TPAPKRKRSPPL------GGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASS 136
            TPK +  TP+ K   SPP        GAPSP  L +PP       A   PSP  +    +
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-------AVTSPSPKEAPTPPA 1618

Query: 137  RYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPP---DCPVGGPLTFPGRGSG 193
              PP P    A   P+ +P  P     P  P  LK +   P    C +G  +    +G  
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSP-----PVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673

Query: 194  AGVG-TTLTPLPPPKMPPPTILSTVP 218
            A  G T L  +     P  T + T P
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAP 1699



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 39/136 (28%), Positives = 49/136 (36%), Gaps = 33/136 (24%)

Query: 75   SSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLA 134
            SS   +   TP     PA     SP   GAP+P + + P   G P      PSP  +   
Sbjct: 915  SSSPKKARATPAPKGIPA-----SPSPKGAPTPPAATPPSPKGGP----ATPSPKWAPTP 965

Query: 135  SSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGA 194
             +  PP P    A   P+ +P  P              A  PP  P GGP T   +G+  
Sbjct: 966  PAATPPSPKGGPATPSPKGAPTPP--------------AATPPS-PKGGPATPSPKGA-- 1008

Query: 195  GVGTTLTPLPPPKMPP 210
                   P PP   PP
Sbjct: 1009 -------PTPPAVTPP 1017



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 29/158 (18%)

Query: 90   TPAPKRKRSPPLGGAPSPSS-LSLPPSTGFPLQASGVP----------SPYLSSLASSRY 138
            TP+PK   + P    PSP   L+ P   G P   +  P          SP  +    +  
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247

Query: 139  PPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKM---------AVGPPDCPVGGPLTFPG 189
            PP P    A   P+ +P  P     P L   L           AV  P  P GGP T P 
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306

Query: 190  RGSG--------AGVGTTLTPLPPPKMPPPTILSTVPR 219
            +G+         +  G+  TP P     PP +    P+
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 36/161 (22%)

Query: 67   SSDSDATASSDNSETEGTPKLSD-TPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGV 125
            +S S   A +  + T  +PK    TP+PK   +PP    PSP      PS        G 
Sbjct: 932  ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS------PKGA 985

Query: 126  PSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPL 185
            P+P  ++      PP P    A   P+ +P  P              AV PP  P G P 
Sbjct: 986  PTPPAAT------PPSPKGGPATPSPKGAPTPP--------------AVTPPS-PKGSPA 1024

Query: 186  T--FPGRGSGAGVGTTLTP------LPPPKMPPPTILSTVP 218
               FP   S     T  +P       P PK  P T  +T+P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 45/157 (28%), Positives = 56/157 (35%), Gaps = 14/157 (8%)

Query: 67   SSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLS---LPPSTGFPLQAS 123
            S+   AT  S       TP     P       P   G P+  SL     PP+   P    
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092

Query: 124  G--VPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPV 181
            G   PSP  + +  +  PP P   LA    + +P  P     P  P K  +A  PP    
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP--AATPPSP-KGGLATPPPKGAP 1149

Query: 182  GGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVP 218
              P   P    G G+ T     PPPK  P T  +T P
Sbjct: 1150 TTPAATPPSPKG-GLAT-----PPPKGAPTTPAATPP 1180



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 8/160 (5%)

Query: 84   TPKLSDTPAPKRKR-SPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLS-SLASSRYPPF 141
            TP  +  P+PK    +PP  GAP+P +++ P   G P   +  PS     +  SS+  P 
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370

Query: 142  PSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGP---PDCPVGGPLTFPGRGSGAGVGT 198
            P          P+   P  ++ P +P        P   P  P   P T P    GA    
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-PVTREGAAT-P 1428

Query: 199  TLTPLPPPKMPPPTILSTVPRQMFSDAGSGDDALDGDDDL 238
            +   L PP + P + L   P       G    +  GD  L
Sbjct: 1429 SKGDLTPPAVTPVS-LKKAPATSAPKGGPATPSSKGDPTL 1467



 Score = 35.8 bits (81), Expect = 0.035
 Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 14/153 (9%)

Query: 81   TEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSS------LA 134
            ++G P L     P  K  P      + SS    P+T  P+ A  +P+   SS        
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520

Query: 135  SSRYPPFPSDYLALQLPEPSPLRPKREKRPRL-----PRKLKMAVGPPDCPVGGPLTFPG 189
            SSR  P       L    P+ L PK    P       P+K      P + P   P +   
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP-ATPSSKEA 1579

Query: 190  RGSGAGVGTTLTPLPPPK--MPPPTILSTVPRQ 220
                A   +T    P PK  + PP + S  P++
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 40/154 (25%), Positives = 51/154 (33%), Gaps = 23/154 (14%)

Query: 68   SDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPS 127
            S   A A+    E   TP   D   P          A +P SL   P+T  P      PS
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPP----------AVTPVSLKKAPATSAPKGGPATPS 1460

Query: 128  ----PYLSSLA--SSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPV 181
                P L ++   S + PP P        P+ +P  P     P LP  +      P  P 
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI------PSSPK 1514

Query: 182  GGPLTFPGRGSG-AGVGTTLTPLPPPKMPPPTIL 214
              P T   R    A   T L+   P  + P   L
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548



 Score = 28.9 bits (63), Expect = 4.3
 Identities = 43/167 (25%), Positives = 59/167 (35%), Gaps = 27/167 (16%)

Query: 67  SSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPS-----PSSLSLPPSTGFPLQ 121
           S+ + A+     S    TP     P      + PLG AP      P+ +  P S      
Sbjct: 59  SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118

Query: 122 ASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPV 181
           AS + +P L    SS  P      LAL    P  ++      P L         PP   V
Sbjct: 119 ASPMIAPTLKGTPSSSAP------LALVALAPHSVQKSSAFPPNL------LTSPPSVAV 166

Query: 182 ---GGPLTFPGRGSGAGVGTTLTPLPPPKMP-------PPTILSTVP 218
              G  +T     + +   T L  +P   +P       PP I+STVP
Sbjct: 167 AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213


>gi|40807452 peroxisome proliferator-activated receptor gamma,
            coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 43/159 (27%), Positives = 57/159 (35%), Gaps = 18/159 (11%)

Query: 84   TPKLSDTPAPKRKRSPPLGGAPSPSSLSLPP--STGFPLQASGV-PSPYLSSLASSRYPP 140
            +P +   P+       P GG   P SL  PP      PL    V P P+        +P 
Sbjct: 866  SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPC 925

Query: 141  FP----SDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVG--------GPLTFP 188
            +P    S Y  L  P   PL         +P    +   PP  PV         GPL   
Sbjct: 926  YPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPL--- 982

Query: 189  GRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGS 227
            G G G       + +PPP +PP +I   VP+      G+
Sbjct: 983  GWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGT 1021



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 40/129 (31%), Positives = 49/129 (37%), Gaps = 22/129 (17%)

Query: 85  PKLSDTPAPKRK----RSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPP 140
           P L   PAP +K    RSP      +P  + L P    P   S  P P    +ASS    
Sbjct: 793 PCLVIPPAPAKKTALQRSPE-----TPLEICLVPVGPSPASPSPEP-PVSKPVASSPTEQ 846

Query: 141 FPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTL 200
            PS  + L L  PSP  P +   P +P    M+   P         FP  G G       
Sbjct: 847 VPSQEMPL-LARPSP--PVQSVSPAVPTPPSMSAALP---------FPAGGLGMPPSLPP 894

Query: 201 TPLPPPKMP 209
            PL PP +P
Sbjct: 895 PPLQPPSLP 903


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 38/135 (28%), Positives = 55/135 (40%), Gaps = 17/135 (12%)

Query: 90  TPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQ 149
           +P P++    P   A SPS L L P    P + S   S  LS  ++ +  P  S   A  
Sbjct: 558 SPLPEQPLDSPAAPALSPSGLGLQPG---PERTSTTKSKELSPGSAQKGSPGSSQGTACA 614

Query: 150 LPEP------------SPLRPKREKRPRLPRKL--KMAVGPPDCPVGGPLTFPGRGSGAG 195
             +P            SP +P  ++ P   RK+  K+A  PP  P G P     + +G  
Sbjct: 615 GTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQP 674

Query: 196 VGTTLTPLPPPKMPP 210
              +L+P PP    P
Sbjct: 675 SPVSLSPTPPSTPSP 689



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 74  ASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSP--YLS 131
           A +D S  + +P +S +P P    SP   G   P   SL      P  A  + SP  + S
Sbjct: 665 AMADQSAGQPSP-VSLSPTPPSTPSPY--GLSYPQGYSLASGQLSPAAAPPLASPSVFTS 721

Query: 132 SLASSRYPPFPSDYLALQLPEP 153
           +L+ SR  P P     L  P+P
Sbjct: 722 TLSKSRPTPKPRQRPTLPPPQP 743


>gi|47519490 reticulon 4 isoform D [Homo sapiens]
          Length = 392

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 26/183 (14%)

Query: 59  QYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGF 118
           +Y+ V E   + +     +  E E    L +    +RK +  L  AP P++    P+ G 
Sbjct: 24  KYQFVREPEDEEEEEEEEEEDEDED---LEELEVLERKPAAGLSAAPVPTA----PAAGA 76

Query: 119 PLQASGV---------PSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRK 169
           PL   G          P P    +A  R P +    ++  +P PSPL        +LP  
Sbjct: 77  PLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPED 136

Query: 170 LKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGD 229
            +    PP  P       P   S         P P P  PP T     P++  S +GS D
Sbjct: 137 DEPPARPPPPP-------PASVSPQAEPVWTPPAPAPAAPPST--PAAPKRRGS-SGSVD 186

Query: 230 DAL 232
           + L
Sbjct: 187 ETL 189


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 26/183 (14%)

Query: 59  QYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGF 118
           +Y+ V E   + +     +  E E    L +    +RK +  L  AP P++    P+ G 
Sbjct: 24  KYQFVREPEDEEEEEEEEEEDEDED---LEELEVLERKPAAGLSAAPVPTA----PAAGA 76

Query: 119 PLQASGV---------PSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRK 169
           PL   G          P P    +A  R P +    ++  +P PSPL        +LP  
Sbjct: 77  PLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPED 136

Query: 170 LKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSGD 229
            +    PP  P       P   S         P P P  PP T     P++  S +GS D
Sbjct: 137 DEPPARPPPPP-------PASVSPQAEPVWTPPAPAPAAPPST--PAAPKRRGS-SGSVD 186

Query: 230 DAL 232
           + L
Sbjct: 187 ETL 189


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 51/188 (27%), Positives = 65/188 (34%), Gaps = 37/188 (19%)

Query: 81   TEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPP 140
            TE  P+     AP      P    P+P+     P T   L+ +  PS  +SS       P
Sbjct: 1044 TERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETS--LERAPAPSAVVSSRNGGETAP 1101

Query: 141  FPSDYLALQLPEPSPLRPKREKR-------PRLPRKLKMAVGPPDCPVGGPLTFPGRGSG 193
             P        P+   L P  E+R       PR P   ++ +G       G  T PG G G
Sbjct: 1102 GPLG----PAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPG 1157

Query: 194  AGV--------GTTLTPLPPPKMPPPTI----LSTVPRQMFSDA------------GSGD 229
            +GV         T   P PPP  PPP      L   P +   +               GD
Sbjct: 1158 SGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGD 1217

Query: 230  DALDGDDD 237
             AL GD D
Sbjct: 1218 TALSGDGD 1225



 Score = 32.3 bits (72), Expect = 0.39
 Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 17/107 (15%)

Query: 91  PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSP--------YLSSLASSRYPPFP 142
           P P     PP   AP+  + S  P +      SG+ SP        Y +    S    FP
Sbjct: 778 PPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFP 837

Query: 143 SDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPG 189
               A +   P P  P     P  PR       PPD    GPL  PG
Sbjct: 838 GGGAAEEEGVPRPRAPPEPPDPGAPRP------PPD---PGPLPLPG 875



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 46/181 (25%), Positives = 64/181 (35%), Gaps = 25/181 (13%)

Query: 64  DEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQAS 123
           D +   +  T + D +E  G  +    P  + +     G +P   S SL    G P +  
Sbjct: 640 DPEGRGAGETLAGDPAEVLG--ERGTAPWVEEEEEEEEGSSPGEDSSSLG---GGPSRRG 694

Query: 124 GVPSPYLSSLASSRYPPFP--------SDYLALQLPEP----SPLRPKREKRPRLPRKLK 171
            +P P  S   +    P            + AL  P P    S LR +R     LP    
Sbjct: 695 PLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMA-P 753

Query: 172 MAVGPPDC--PVGGPLT--FPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGS 227
            A  PP+   P+ G     +PGRG          P PPP+ P     S  P    +  GS
Sbjct: 754 PASAPPEFLDPLMGAAAPQYPGRGPPPAPPP---PPPPPRAPADPAASPDPPSAVASPGS 810

Query: 228 G 228
           G
Sbjct: 811 G 811


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 45/145 (31%), Positives = 50/145 (34%), Gaps = 36/145 (24%)

Query: 72  ATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLS 131
           AT S  ++ T G P  S +P       P  G AP P     PP  G P      PS    
Sbjct: 509 ATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP----PPLPGLPSPQEAPPS---- 560

Query: 132 SLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVG--GPLTFPG 189
             A  + PP P        PEP P  P       LP  L     PP  P G  GP+  P 
Sbjct: 561 --APPQAPPLPGS------PEPPPAPP-------LPGDLPPPPPPPPPPPGTDGPVPPPP 605

Query: 190 RGSGAGVGTTLTPLPPPKMPPPTIL 214
                       P PPP   PP  L
Sbjct: 606 -----------PPPPPPPGGPPDAL 619



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 40/127 (31%), Positives = 48/127 (37%), Gaps = 30/127 (23%)

Query: 93  PKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPE 152
           P    +P  G AP+P         G P   +G PSP L+  A       P+   A   P 
Sbjct: 505 PVAVATPSGGDAPTP---------GVP---TGSPSPDLAPAAE------PAPGAAPPPPP 546

Query: 153 PSPLRPK-REKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPP 211
           P P  P  +E  P  P +     G P+ P   PL  PG          L P PPP  PPP
Sbjct: 547 PLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPL--PG---------DLPPPPPPPPPPP 595

Query: 212 TILSTVP 218
                VP
Sbjct: 596 GTDGPVP 602


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 43/129 (33%), Positives = 49/129 (37%), Gaps = 27/129 (20%)

Query: 83  GTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFP 142
           G P     P P +   PPL G P+      PP   FP Q  G   P L  L     PP P
Sbjct: 245 GPPGPPGPPPPGQVLPPPLAGPPNRGDRP-PPPVLFPGQPFG--QPPLGPLPPGPPPPVP 301

Query: 143 SDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTP 202
                   P P P  P++              GPP  P  GP  FP R  G  +G  LT 
Sbjct: 302 G-----YGPPPGPPPPQQ--------------GPP--PPPGP--FPPRPPGP-LGPPLTL 337

Query: 203 LPPPKMPPP 211
            PPP +P P
Sbjct: 338 APPPHLPGP 346



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 11/78 (14%)

Query: 139 PPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDC--PVGG-----PLTFPGRG 191
           PPFP+     Q P   PL P     P  P      + PP    P  G     P+ FPG+ 
Sbjct: 228 PPFPAG----QTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283

Query: 192 SGAGVGTTLTPLPPPKMP 209
            G      L P PPP +P
Sbjct: 284 FGQPPLGPLPPGPPPPVP 301



 Score = 28.5 bits (62), Expect = 5.6
 Identities = 41/156 (26%), Positives = 51/156 (32%), Gaps = 29/156 (18%)

Query: 91  PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASG--------VPSPYLSSLASSRYPPFP 142
           P P     PP  G P P     PP   FP +  G         P P+L        PP P
Sbjct: 297 PPPVPGYGPP-PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355

Query: 143 SDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGS----GAGVGT 198
               A   P  +   P  + R            PP  P G P  +  RG     G  + T
Sbjct: 356 HVNPAFFPPPTNSGMPTSDSRG----------PPPTDPYGRPPPY-DRGDYGPPGREMDT 404

Query: 199 TLTPLPPPKMPP-----PTILSTVPRQMFSDAGSGD 229
             TPL   +          I S+   +  SDA +GD
Sbjct: 405 ARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGD 440


>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
          Length = 474

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 59/223 (26%), Positives = 87/223 (39%), Gaps = 46/223 (20%)

Query: 17  NLKRKLKFLIYEHECFQEELRKAQ----RKLLKV------SRDKSFLLDRLLQYENVDED 66
           N+ R ++FL  E E  +++LR AQ     K+ +        R+++  L R LQ E    +
Sbjct: 257 NMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERRE 316

Query: 67  SSDSDATASSDNSETEGTPKLSDTPAP---KRKRSPPLGGAPSPSSLSLPPSTGFPLQAS 123
           +     + S  + E +     ++  A     R  S P+   PSPSS S P S G    + 
Sbjct: 317 ALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSS-SRPISPGLSYASH 375

Query: 124 GVPSPYLSSLASSRYPPFPSDYLALQ-------LPEPSPLRPKREKRPRLPRKLKMAVGP 176
            V     +SL  +    + S  L +Q       +  PSP      +R   P K K    P
Sbjct: 376 TVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSP------RRSNSPDKFKRPTPP 429

Query: 177 PDCPVGGPLTFPGRGSGAGVGTTLTPL-PPPKMPPPTILSTVP 218
           P                     T TP+ PPP  PPP +  TVP
Sbjct: 430 PS------------------PNTQTPVQPPPPPPPPPMQPTVP 454


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 13/161 (8%)

Query: 58  LQYENVDEDSSDSDATASSDNSETEGTPKL-SDTPAPKRKRSPPLGGAPSPSSLSLPPST 116
           L  +++D    + D  A+  +  T+    L SD+PAP   ++ P    P  SS S+P   
Sbjct: 20  LAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPE-- 77

Query: 117 GFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPK-REKRPRLPRKLKM-AV 174
             P  + G P    +  A +   PF     A  L   SPL PK R   PR P  L+  A 
Sbjct: 78  --PFGSRGSPRKAATDGADT---PFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAY 132

Query: 175 GPPDCPVG-GPLTFPGRGSGAGVGTTLTPLPPP--KMPPPT 212
           G  D      P  F G GS  G   +  P P P  +  PPT
Sbjct: 133 GSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 36/132 (27%), Positives = 46/132 (34%), Gaps = 27/132 (20%)

Query: 60  YENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPP-----LGGAPSPSSLSL-- 112
           Y ++D  +S          S     P     P P R++ PP     LG A SP    L  
Sbjct: 132 YGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAE 191

Query: 113 --------------PPSTGFPLQASGVPSPYLSSLASSRYPPF-PSDYLALQLPEP---- 153
                         PP+T +   AS   S  L S  S+  PP    D L L+   P    
Sbjct: 192 GPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWN 251

Query: 154 -SPLRPKREKRP 164
            S L    EK+P
Sbjct: 252 ESDLDVAYEKKP 263


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 13/161 (8%)

Query: 58  LQYENVDEDSSDSDATASSDNSETEGTPKL-SDTPAPKRKRSPPLGGAPSPSSLSLPPST 116
           L  +++D    + D  A+  +  T+    L SD+PAP   ++ P    P  SS S+P   
Sbjct: 20  LAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPE-- 77

Query: 117 GFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPK-REKRPRLPRKLKM-AV 174
             P  + G P    +  A +   PF     A  L   SPL PK R   PR P  L+  A 
Sbjct: 78  --PFGSRGSPRKAATDGADT---PFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAY 132

Query: 175 GPPDCPVG-GPLTFPGRGSGAGVGTTLTPLPPP--KMPPPT 212
           G  D      P  F G GS  G   +  P P P  +  PPT
Sbjct: 133 GSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173



 Score = 30.4 bits (67), Expect = 1.5
 Identities = 36/132 (27%), Positives = 46/132 (34%), Gaps = 27/132 (20%)

Query: 60  YENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPP-----LGGAPSPSSLSL-- 112
           Y ++D  +S          S     P     P P R++ PP     LG A SP    L  
Sbjct: 132 YGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAE 191

Query: 113 --------------PPSTGFPLQASGVPSPYLSSLASSRYPPF-PSDYLALQLPEP---- 153
                         PP+T +   AS   S  L S  S+  PP    D L L+   P    
Sbjct: 192 GPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWN 251

Query: 154 -SPLRPKREKRP 164
            S L    EK+P
Sbjct: 252 ESDLDVAYEKKP 263


>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
          Length = 1505

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 12/124 (9%)

Query: 66   DSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGV 125
            ++++   +A ++  +++G  +  + P P  +  PP  G P P         G P++  G 
Sbjct: 1342 EATEGPGSADTEEPKSQGEAEREEVPRPAEQTEPPPSGTPGPDDARDDDHEGGPVEGPG- 1400

Query: 126  PSPYLSSLASSRYPPFPSDYL-----------ALQLPEPSPLRPKREKRPRLPRKLKMAV 174
            P P  +S  ++  P  P D             A     P P        PR P  L+   
Sbjct: 1401 PLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQSLF 1460

Query: 175  GPPD 178
            G P+
Sbjct: 1461 GLPE 1464


>gi|24431933 reticulon 4 isoform B [Homo sapiens]
          Length = 373

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 40/163 (24%), Positives = 58/163 (35%), Gaps = 23/163 (14%)

Query: 59  QYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGF 118
           +Y+ V E   + +     +  E E    L +    +RK +  L  AP P++    P+ G 
Sbjct: 24  KYQFVREPEDEEEEEEEEEEDEDED---LEELEVLERKPAAGLSAAPVPTA----PAAGA 76

Query: 119 PLQASGV---------PSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRK 169
           PL   G          P P    +A  R P +    ++  +P PSPL        +LP  
Sbjct: 77  PLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPED 136

Query: 170 LKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPT 212
            +    PP  P       P   S         P P P  PP T
Sbjct: 137 DEPPARPPPPP-------PASVSPQAEPVWTPPAPAPAAPPST 172


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 3/129 (2%)

Query: 84  TPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPS 143
           +P   ++P        P+   P  S L  PP    PL      SP      +SR  P P 
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRL-FPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631

Query: 144 DYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPL 203
           D      PE SP+ P  E     P  +   + PP  P   PL+ P   S        + L
Sbjct: 632 DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEASRL 689

Query: 204 PPPKMPPPT 212
            PP    PT
Sbjct: 690 SPPPEDSPT 698



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 43/147 (29%), Positives = 53/147 (36%), Gaps = 9/147 (6%)

Query: 80  ETEGTPKLSDTPAPKRKRSPPL--GGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSR 137
           E+  +P+L   P   R   PP   G  P+P  L L P  G P  +  +  P LS      
Sbjct: 848 ESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907

Query: 138 YPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLK---MAVGPPDCPVGGPLTFP--GRGS 192
             P P +       EPS L P+      LP  L     A  PP     G L +P   +G 
Sbjct: 908 LSPLPEELPLSPSGEPS-LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGD 966

Query: 193 GAGVGTTLTP-LPPPKMPPPTILSTVP 218
                    P L  P  PPP    T P
Sbjct: 967 SDPESPLAAPILETPISPPPEANCTDP 993



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 38/122 (31%), Positives = 43/122 (35%), Gaps = 7/122 (5%)

Query: 104 APSPSSLSLPPSTGFPLQASGVPSPYLSSLAS-SRYPPFPSDYLALQLPEPSPLRPKREK 162
           +P P  L L P T  P  +     P LS     S   P   +      PE S L P+ EK
Sbjct: 798 SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857

Query: 163 RPRLPRKLKMAVGPPDCPVGGPL-TFPGRGSGA-----GVGTTLTPLPPPKMPPPTILST 216
            P  PR  K    P  CP    L  FP  G  +     G      P  PP  P P  L  
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917

Query: 217 VP 218
            P
Sbjct: 918 SP 919



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 14/139 (10%)

Query: 78  NSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSR 137
           N E    P   ++P        P    P  S LS PP     L AS +P     S     
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE---LPASPLPEALHLSRPLEE 491

Query: 138 YPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCP----VGGPLTFPGRGSG 193
            P  P        PE SPL P  E  P  P +      P + P    +  PL+ P   S 
Sbjct: 492 SPLSPP-------PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544

Query: 194 AGVGTTLTPLPPPKMPPPT 212
                  +PL PP    PT
Sbjct: 545 LSPPFEESPLSPPPEELPT 563



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 36/129 (27%), Positives = 44/129 (34%), Gaps = 9/129 (6%)

Query: 90  TPAPKRKRSPPLGGAPSPSSLSLPPSTGF--PLQASGVPSPYLSSLASSRYPPFPSDYLA 147
           +P P+     PL  +P       PPS     PL      SP       S   P P +   
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT 563

Query: 148 LQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPK 207
              PE S L P  E+ P  P   +  + PP  P    L  P   S        +PL PP 
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPP--PEASRLFPPFEESPLSPPPEESPLSPPP 621

Query: 208 -----MPPP 211
                 PPP
Sbjct: 622 EASRLSPPP 630



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 48/202 (23%), Positives = 72/202 (35%), Gaps = 28/202 (13%)

Query: 27  YEHECFQEELRKAQ--RKLLKVSRDKSFLLDRLLQYENVDEDSSDSDATASSDNSETEG- 83
           +E+        KAQ  + +  V+   + +  R    E  D  + + DA   +   + +G 
Sbjct: 340 FENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGG 399

Query: 84  --TPKLSDTPAPKRKRSPPLGGA----------PSPSSLSL-PPSTGFPLQASGVPSPYL 130
             T      P P +  + PLG A          P    + L PP    PL      SP  
Sbjct: 400 HVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS 459

Query: 131 SSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGR 190
               +SR  P P +  A  LPE   L    E+ P  P   +  + PP  P   P +    
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP--PESSPFS---- 513

Query: 191 GSGAGVGTTLTPLPPPKMPPPT 212
                     +PL PP+  PP+
Sbjct: 514 ------PLEESPLSPPEESPPS 529



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 45/164 (27%), Positives = 65/164 (39%), Gaps = 31/164 (18%)

Query: 85   PKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPP---- 140
            P L +   P+   SP +GG  +   L  PP  G   +A  V    L + + S  PP    
Sbjct: 2250 PSLDNLAVPE---SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306

Query: 141  --FPSD-----YLALQLPE--PSPLRPKREK----------RPRLPRKLK-MAVGPPDCP 180
               PS       L L+ P+   +PL P+  +          RP+ P   + +A  PP  P
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHP 2366

Query: 181  VGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSD 224
                +  PG  +       LTP P P  PP +  +  PR + SD
Sbjct: 2367 ---DIFRPGSYTDPYAQPPLTPRPQPP-PPESCCALPPRSLPSD 2406



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 40/140 (28%), Positives = 50/140 (35%), Gaps = 29/140 (20%)

Query: 86   KLSDTPAPKRKRSPPLG---GAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFP 142
            K+     P   RSP  G   G PSP   + P + G P     VP P              
Sbjct: 2509 KVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP-------------- 2554

Query: 143  SDYLALQLPEPSPLRPKREKRPRL--PRKLKMAVGPPDC-PVGGPLTFPGRGSGAGVGTT 199
                   LP P  +       P L  P+     V   +  P G PL  P  GS  G    
Sbjct: 2555 ------GLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLG-PSSGS-TGESYG 2606

Query: 200  LTPLPPPK-MPPPTILSTVP 218
            L+PL PP  +PPP    ++P
Sbjct: 2607 LSPLRPPSVLPPPAPDGSLP 2626



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 49/188 (26%), Positives = 65/188 (34%), Gaps = 24/188 (12%)

Query: 58   LQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTG 117
            L+Y    +  SD ++  ++   ET  +P   +      +  PP+   PSP S   P    
Sbjct: 957  LEYPFGAKGDSDPESPLAAPILETPISPP-PEANCTDPEPVPPMILPPSPGS---PVGPA 1012

Query: 118  FPLQASGVP---SPYLS-SLASSRYPPFPSDYLALQLPEPSPLRPKRE-----KRPRLPR 168
             P+    +P   SP L  SL     PP      AL L  PSPL P  +         L  
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072

Query: 169  KLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTILSTVPRQMFSDAGSG 228
                 V  P+CP   P       S  G  +   P P P +             FS  G  
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDD-----------FSGLGED 1121

Query: 229  DDALDGDD 236
               LDG D
Sbjct: 1122 TAPLDGID 1129



 Score = 32.0 bits (71), Expect = 0.50
 Identities = 39/112 (34%), Positives = 43/112 (38%), Gaps = 13/112 (11%)

Query: 65  EDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPS---TGFPLQ 121
           EDS  S     S  S      +LS  P   R  SPP    P  S LS PP    T  P +
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL-SPP----PEESPLSPPPEESPTSPPPE 685

Query: 122 ASGVPSPYLSSLAS-----SRYPPFPSDYLALQLPEPSPLRPKREKRPRLPR 168
           AS +  P   S  S     S   P P D L     E SPL P  E+    PR
Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737



 Score = 29.6 bits (65), Expect = 2.5
 Identities = 30/110 (27%), Positives = 37/110 (33%), Gaps = 17/110 (15%)

Query: 85  PKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGF----PLQASGVPSPYLSSLAS----S 136
           P   ++P        PL   P  S LS PP        P ++   P P +S L+     S
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660

Query: 137 RYPPFPSDYLALQLPEPSP---------LRPKREKRPRLPRKLKMAVGPP 177
           R  P P +      PE SP         L P  E  P  P        PP
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710



 Score = 28.1 bits (61), Expect = 7.3
 Identities = 24/74 (32%), Positives = 28/74 (37%), Gaps = 15/74 (20%)

Query: 91   PAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQL 150
            P P+    PP   APSP+S    P    P +           LA    PP PS       
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTE----------PLAE---PPVPSPLPLASS 4955

Query: 151  PEPSPLRPKREKRP 164
            PE +  RPK   RP
Sbjct: 4956 PESA--RPKPRARP 4967


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 51/192 (26%), Positives = 67/192 (34%), Gaps = 30/192 (15%)

Query: 52  FLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLS 111
           F L  L     VDE   +     + +  + E     S +P P R   PP    P P    
Sbjct: 46  FGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP---- 101

Query: 112 LPPSTGFPLQASGVP--SPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREK------- 162
            PP    PL A  +P   PY    A   +P +  D   L +P+P P   KR +       
Sbjct: 102 -PPPLVPPLPAGSLPPYPPYFEG-APFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNR 159

Query: 163 ------------RPR--LPRKLKMAVGPPDCPVGGPLTFPGRGS-GAGVGTTLTPLPPPK 207
                       RPR  L  K K  + PP+   G P     R   G+G    L     P+
Sbjct: 160 DPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPE 219

Query: 208 MPPPTILSTVPR 219
              PT  +T  R
Sbjct: 220 NGEPTAAATARR 231


>gi|148839311 PWWP domain containing 2 isoform 2 [Homo sapiens]
          Length = 499

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 51/192 (26%), Positives = 67/192 (34%), Gaps = 30/192 (15%)

Query: 52  FLLDRLLQYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLS 111
           F L  L     VDE   +     + +  + E     S +P P R   PP    P P    
Sbjct: 46  FGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEP---- 101

Query: 112 LPPSTGFPLQASGVP--SPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREK------- 162
            PP    PL A  +P   PY    A   +P +  D   L +P+P P   KR +       
Sbjct: 102 -PPPLVPPLPAGSLPPYPPYFEG-APFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNR 159

Query: 163 ------------RPR--LPRKLKMAVGPPDCPVGGPLTFPGRGS-GAGVGTTLTPLPPPK 207
                       RPR  L  K K  + PP+   G P     R   G+G    L     P+
Sbjct: 160 DPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPE 219

Query: 208 MPPPTILSTVPR 219
              PT  +T  R
Sbjct: 220 NGEPTAAATARR 231


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 39/155 (25%), Positives = 54/155 (34%), Gaps = 27/155 (17%)

Query: 59  QYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGF 118
           + +  + +  ++      D+     +P  S +P P  +  PP    PSP    LPPST  
Sbjct: 57  EQQTPEPEPGEAGRDGMGDSGRDSRSPD-SSSPNPLPQGVPP----PSPPGPPLPPSTAP 111

Query: 119 PLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPD 178
            L  SG P P          PP P   L    P  S         P  P      V  P 
Sbjct: 112 SLGGSGAPPP----------PPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQ 161

Query: 179 CPVGGPLTFPGRGSGAGVGTTLTPLPPPKMPPPTI 213
             +   ++ PG GSG          PP  + PP +
Sbjct: 162 --INSTVSLPGGGSG----------PPEDVKPPVL 184



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 28/81 (34%), Positives = 29/81 (35%), Gaps = 16/81 (19%)

Query: 149 QLPEPSPL-----------RPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVG 197
           Q PEP P            R  R      P  L   V PP  P G PL      S  G G
Sbjct: 59  QTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPS-PPGPPLPPSTAPSLGGSG 117

Query: 198 TTLTPLPPPKMPPPTILSTVP 218
                 PPP MPPP + S  P
Sbjct: 118 AP----PPPPMPPPPLGSPFP 134


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 40/153 (26%), Positives = 55/153 (35%), Gaps = 26/153 (16%)

Query: 59   QYENVDEDSSDSDATASSDNSETEGTPKLSDTPAPKR-------KRSPPLGGAPSPSSLS 111
            +YE + +      +   S+  E++  P   + P PK           PP G  PSP+   
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPAR 1152

Query: 112  LPPSTGFPLQASGVPSPYLSSLASSRYPPF-------PSDYLALQLPEPSPLRPKREKRP 164
                 G      GVPS         R PP        P+  LA + P   PL P +E   
Sbjct: 1153 FTARGGRVFTPRGVPS--RRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKE--- 1207

Query: 165  RLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVG 197
              P K K+  GP       P+   G   G+ VG
Sbjct: 1208 --PLKEKLIPGPL-----SPVARGGSNGGSNVG 1233



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 5/126 (3%)

Query: 65   EDSSDSDATASSDNSETEGTPKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASG 124
            ED + ++ + S    +  G  ++S  P  +R  SP  G   +       P    PL A  
Sbjct: 1639 EDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRS-SPDGGLKGAAEGPPKRPGGSSPLNAVP 1697

Query: 125  VPSPYLSSLASSRYPPFPSDYLALQLPEPSPLRP---KREKRPRLPRKLKMAVGPPDCPV 181
               P   S    R PP P D    +LP   PL P     E+  R  R  +     P    
Sbjct: 1698 CEGPP-GSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRP 1756

Query: 182  GGPLTF 187
            G P+ F
Sbjct: 1757 GPPVQF 1762



 Score = 28.1 bits (61), Expect = 7.3
 Identities = 44/198 (22%), Positives = 55/198 (27%), Gaps = 45/198 (22%)

Query: 64  DEDSSDSDATASSDNSETE---------------GTPKLSDTPAPKR-----KRSPPLGG 103
           +ED  DSD   +  + +++               G    S+ P PK       R P    
Sbjct: 344 EEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEP 403

Query: 104 APSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSD------------------- 144
            P      LPP    P    G P  Y         PP P D                   
Sbjct: 404 GPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463

Query: 145 -YLALQLPEPSPLRPKREKRPRLPRKLKM---AVGPPDCPVGGPLTFPGRGSGAGVGTTL 200
              A +  E    R + E+R     KLK      G PD  +      P            
Sbjct: 464 VERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPA 523

Query: 201 TP--LPPPKMPPPTILST 216
            P  LP P  PPP    T
Sbjct: 524 VPKELPAPPAPPPASAPT 541



 Score = 28.1 bits (61), Expect = 7.3
 Identities = 33/132 (25%), Positives = 50/132 (37%), Gaps = 22/132 (16%)

Query: 79  SETEGTPKLSDTPAP--------KRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVP---- 126
           +E    P    TPAP            +PP   AP+P +    P+   P Q++  P    
Sbjct: 506 AEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAA 565

Query: 127 SPYL----SSLASSRYPPFPSDYLALQLP-EPSPLRPKREKRPRLPRKLKM-----AVGP 176
           +P L     S +S+    F +  +  QLP +  P  P+    P  P   K+      +GP
Sbjct: 566 APTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGP 625

Query: 177 PDCPVGGPLTFP 188
              P    L +P
Sbjct: 626 TRQPPSQGLGYP 637



 Score = 27.7 bits (60), Expect = 9.5
 Identities = 30/125 (24%), Positives = 44/125 (35%), Gaps = 23/125 (18%)

Query: 94  KRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDYLALQLPEP 153
           KR ++ P     +PS+ + PP+    L A   P P                  +   PE 
Sbjct: 502 KRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPP-----------------ASAPTPET 544

Query: 154 SPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGS--GAGVGTTLT----PLPPPK 207
            P  P +    +      +A  P     GG  +    GS   + V   L     P PP +
Sbjct: 545 EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEE 604

Query: 208 MPPPT 212
           +PPPT
Sbjct: 605 VPPPT 609


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 53/186 (28%), Positives = 69/186 (37%), Gaps = 49/186 (26%)

Query: 85  PKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFP-----LQASGVPS------PYLSSL 133
           P     P P +  S P GG+P PS    PPST  P     L+    PS      P L +L
Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPS----PPSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197

Query: 134 A-----SSRYPPFPSDY------LALQLPEPSPLRPKREKRPRLPRKLKMAVGPP----- 177
           +     SS   P P D+      LA   P P P+       P  P  +   + PP     
Sbjct: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTK 257

Query: 178 ---DCPVGG-----PLTFPGRGSGAGVGTTLTPLPPP--------KMPPPTIL--STVPR 219
              D  + G         P R      G+ L P P P        K+PPPT +  S++P 
Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317

Query: 220 QMFSDA 225
           Q   +A
Sbjct: 318 QEAQEA 323



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 39/150 (26%), Positives = 56/150 (37%), Gaps = 24/150 (16%)

Query: 78  NSETEGTPKLSDTPAPKRKRSPPLGGAPSPS-----SLSLPPSTGFPLQASGVP------ 126
           N       + S   +P   +   LG  P P      S  +PP T  P++ S +P      
Sbjct: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQE 322

Query: 127 SPYLSSLASSRYP---PFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGG 183
           +P     A+ + P   P P  +    +   S + P R   P  P +LK A  P    +G 
Sbjct: 323 APRKEEGATKKAPSRLPLPPSF---HIRPASQVYPDRAPEPDCPGELK-ATAPASPRLGQ 378

Query: 184 PLTFPGRGSGAGVGTTLTPLPPP--KMPPP 211
             +       AG      PLPPP   +PPP
Sbjct: 379 SQS--QADERAGTPPPAPPLPPPAPPLPPP 406



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 18/119 (15%)

Query: 86  KLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDY 145
           ++ +  A   K S P+     P S +L P+T   LQ   +  P +   A+          
Sbjct: 599 RICENGADDDKLSKPVAKNLPPQSTTLLPTTS--LQPKAMLGPAIPPKAT---------- 646

Query: 146 LALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLP 204
                PEP+ + PK    P  P K  +    P     GP T     SG  + +T T LP
Sbjct: 647 -----PEPA-IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLP 699


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 53/186 (28%), Positives = 69/186 (37%), Gaps = 49/186 (26%)

Query: 85  PKLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFP-----LQASGVPS------PYLSSL 133
           P     P P +  S P GG+P PS    PPST  P     L+    PS      P L +L
Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPS----PPSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197

Query: 134 A-----SSRYPPFPSDY------LALQLPEPSPLRPKREKRPRLPRKLKMAVGPP----- 177
           +     SS   P P D+      LA   P P P+       P  P  +   + PP     
Sbjct: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTK 257

Query: 178 ---DCPVGG-----PLTFPGRGSGAGVGTTLTPLPPP--------KMPPPTIL--STVPR 219
              D  + G         P R      G+ L P P P        K+PPPT +  S++P 
Sbjct: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317

Query: 220 QMFSDA 225
           Q   +A
Sbjct: 318 QEAQEA 323



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 39/150 (26%), Positives = 56/150 (37%), Gaps = 24/150 (16%)

Query: 78  NSETEGTPKLSDTPAPKRKRSPPLGGAPSPS-----SLSLPPSTGFPLQASGVP------ 126
           N       + S   +P   +   LG  P P      S  +PP T  P++ S +P      
Sbjct: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQE 322

Query: 127 SPYLSSLASSRYP---PFPSDYLALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGG 183
           +P     A+ + P   P P  +    +   S + P R   P  P +LK A  P    +G 
Sbjct: 323 APRKEEGATKKAPSRLPLPPSF---HIRPASQVYPDRAPEPDCPGELK-ATAPASPRLGQ 378

Query: 184 PLTFPGRGSGAGVGTTLTPLPPP--KMPPP 211
             +       AG      PLPPP   +PPP
Sbjct: 379 SQS--QADERAGTPPPAPPLPPPAPPLPPP 406



 Score = 31.6 bits (70), Expect = 0.66
 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 18/119 (15%)

Query: 86  KLSDTPAPKRKRSPPLGGAPSPSSLSLPPSTGFPLQASGVPSPYLSSLASSRYPPFPSDY 145
           ++ +  A   K S P+     P S +L P+T   LQ   +  P +   A+          
Sbjct: 599 RICENGADDDKLSKPVAKNLPPQSTTLLPTTS--LQPKAMLGPAIPPKAT---------- 646

Query: 146 LALQLPEPSPLRPKREKRPRLPRKLKMAVGPPDCPVGGPLTFPGRGSGAGVGTTLTPLP 204
                PEP+ + PK    P  P K  +    P     GP T     SG  + +T T LP
Sbjct: 647 -----PEPA-IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLP 699


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,246,347
Number of Sequences: 37866
Number of extensions: 945318
Number of successful extensions: 8893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 869
Number of HSP's that attempted gapping in prelim test: 6378
Number of HSP's gapped (non-prelim): 2800
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.