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Search of human proteins with 27501452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27501452 sprouty homolog 3 [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27501452 sprouty homolog 3 [Homo sapiens] 615 e-176
gi|5032115 sprouty 2 [Homo sapiens] 246 1e-65
gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens] 229 3e-60
gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens] 229 3e-60
gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo... 214 7e-56
gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo... 214 7e-56
gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform... 70 2e-12
gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform... 70 2e-12
gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo sa... 69 5e-12
gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a... 67 2e-11
gi|21264602 laminin alpha 5 [Homo sapiens] 36 0.045
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 35 0.076
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 35 0.076
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 35 0.100
gi|221219024 pleckstrin homology-like domain, family B, member 1... 34 0.13
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 34 0.13
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 34 0.17
gi|134244285 Notch homolog 3 [Homo sapiens] 33 0.22
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 33 0.22
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 33 0.22
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 33 0.22
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 33 0.22
gi|55770876 notch4 preproprotein [Homo sapiens] 33 0.29
gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Ho... 33 0.29
gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Hom... 33 0.29
gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Hom... 33 0.29
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 33 0.29
gi|148833508 notch1 preproprotein [Homo sapiens] 33 0.38
gi|148886718 zinc finger, CCHC domain containing 4 [Homo sapiens] 33 0.38
gi|123173777 keratin associated protein 5-8 [Homo sapiens] 33 0.38
>gi|27501452 sprouty homolog 3 [Homo sapiens]
Length = 288
Score = 615 bits (1586), Expect = e-176
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MDAAVTDDFQQILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPT 60
MDAAVTDDFQQILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPT
Sbjct: 1 MDAAVTDDFQQILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPT 60
Query: 61 SLPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAG 120
SLPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAG
Sbjct: 61 SLPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAG 120
Query: 121 VHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRCLCSAES 180
VHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRCLCSAES
Sbjct: 121 VHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRCLCSAES 180
Query: 181 LLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLP 240
LLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLP
Sbjct: 181 LLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLP 240
Query: 241 TRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV 288
TRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV
Sbjct: 241 TRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV 288
>gi|5032115 sprouty 2 [Homo sapiens]
Length = 315
Score = 246 bits (629), Expect = 1e-65
Identities = 125/271 (46%), Positives = 167/271 (61%), Gaps = 16/271 (5%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSL--SQC 69
+L ++Q+R+ +N+Y E P + L HK + P L SQ
Sbjct: 40 VLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQV 99
Query: 70 HQLQPLPQHLSQSSIASSMSHST------TASDQRLL-ASITPSPSGQSIIRTQPGAGVH 122
H P S S+++S ST ++S+QRLL +S + P IIR QP + +
Sbjct: 100 HSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELK 159
Query: 123 PKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLL 182
P G LK +++ G H + CE+CG+CKC CT RPLPS W+C+++CLCSA++++
Sbjct: 160 P---GELKPLSKEDLGL---HAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVI 213
Query: 183 DYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTR 242
DYGTC+CCVKGLFYHCS DDEDNCAD PCSC S C RW+AM ++SLFLPCL CYLP +
Sbjct: 214 DYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAK 273
Query: 243 GCLHLCQQGYDSLRRPGCRCKRHTNTVCRKI 273
GCL LCQ YD + RPGCRCK ++NTVC K+
Sbjct: 274 GCLKLCQGCYDRVNRPGCRCK-NSNTVCCKV 303
>gi|188595697 sprouty homolog 4 isoform 2 [Homo sapiens]
Length = 299
Score = 229 bits (583), Expect = 3e-60
Identities = 124/285 (43%), Positives = 163/285 (57%), Gaps = 49/285 (17%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71
ILPI+Q++++H NDY++ P SLA + T R+ +
Sbjct: 37 ILPIDQVKTSHVENDYIDNP----------------------SLA-LTTGPKRTRGGAPE 73
Query: 72 LQPLPQHLSQ-------------SSIASSMSHSTTASDQRLLASITPSP----SGQSIIR 114
L P P Q SS++SS S+T+SDQRLL + P P + +R
Sbjct: 74 LAPTPARCDQDVTHHWISFSGRPSSVSSS---SSTSSDQRLLDHMAPPPVADQASPRAVR 130
Query: 115 TQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRC 174
QP D LKG A +H +CE CG+CKC C + R LPSCW+CNQ C
Sbjct: 131 IQPKVVHCQPLD--LKGPAVPP--ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQEC 186
Query: 175 LCSAESLLDYGTCLCCVKGLFYHCST-DDEDNCADEPCSCGPSSCFVRWAAMSLISLFLP 233
LCSA++L++YGTC+C V+G+FYHC+ DDE +CAD PCSC S+C RW+ M +S+ LP
Sbjct: 187 LCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLP 246
Query: 234 CLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSA 278
CL CYLP GC+ L Q+GYD LRRPGCRCK HTN+V K +SG A
Sbjct: 247 CLLCYLPATGCVKLAQRGYDRLRRPGCRCK-HTNSVICKAASGDA 290
>gi|23308574 sprouty homolog 4 isoform 1 [Homo sapiens]
Length = 322
Score = 229 bits (583), Expect = 3e-60
Identities = 124/285 (43%), Positives = 163/285 (57%), Gaps = 49/285 (17%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71
ILPI+Q++++H NDY++ P SLA + T R+ +
Sbjct: 60 ILPIDQVKTSHVENDYIDNP----------------------SLA-LTTGPKRTRGGAPE 96
Query: 72 LQPLPQHLSQ-------------SSIASSMSHSTTASDQRLLASITPSP----SGQSIIR 114
L P P Q SS++SS S+T+SDQRLL + P P + +R
Sbjct: 97 LAPTPARCDQDVTHHWISFSGRPSSVSSS---SSTSSDQRLLDHMAPPPVADQASPRAVR 153
Query: 115 TQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRC 174
QP D LKG A +H +CE CG+CKC C + R LPSCW+CNQ C
Sbjct: 154 IQPKVVHCQPLD--LKGPAVPP--ELDKHFLLCEACGKCKCKECASPRTLPSCWVCNQEC 209
Query: 175 LCSAESLLDYGTCLCCVKGLFYHCST-DDEDNCADEPCSCGPSSCFVRWAAMSLISLFLP 233
LCSA++L++YGTC+C V+G+FYHC+ DDE +CAD PCSC S+C RW+ M +S+ LP
Sbjct: 210 LCSAQTLVNYGTCMCLVQGIFYHCTNEDDEGSCADHPCSCSRSNCCARWSFMGALSVVLP 269
Query: 234 CLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSA 278
CL CYLP GC+ L Q+GYD LRRPGCRCK HTN+V K +SG A
Sbjct: 270 CLLCYLPATGCVKLAQRGYDRLRRPGCRCK-HTNSVICKAASGDA 313
>gi|40788001 sprouty homolog 1, antagonist of FGF signaling [Homo
sapiens]
Length = 319
Score = 214 bits (545), Expect = 7e-56
Identities = 119/283 (42%), Positives = 163/283 (57%), Gaps = 30/283 (10%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71
IL ++Q+++ SN+Y E P + A P + K + + +P ++ + H
Sbjct: 38 ILSLDQIKAIRGSNEYTEGPSVVKRPA---PRTAPRQEKHERTHEIIPINVNNNYEHRHT 94
Query: 72 LQP-------------LPQHLSQSSIASSMSHSTTASDQRLLASITPS---PSGQS--II 113
L + S S ASS S+S+ +S+Q LL P+ P +S I
Sbjct: 95 SHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAI 154
Query: 114 RTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQR 173
RTQP + G+LK + Q H FICE+CG+CKC CTA R LPSC CN++
Sbjct: 155 RTQPKQLIVDDLKGSLKEDLTQ-------HKFICEQCGKCKCGECTAPRTLPSCLACNRQ 207
Query: 174 CLCSAESLLDYGTCLCCVKGLFYHCSTDDE-DNCADEPCSCGPSSCFVRWAAMSLISLFL 232
CLCSAES+++YGTC+C VKG+FYHCS DDE D+ +D PCSC S C R+ M +SLFL
Sbjct: 208 CLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLFL 267
Query: 233 PCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISS 275
PCL CY P +GCL LC++ YD + RPGCRCK ++NTV K+ S
Sbjct: 268 PCLLCYPPAKGCLKLCRRCYDWIHRPGCRCK-NSNTVYCKLES 309
>gi|40538726 sprouty homolog 1, antagonist of FGF signaling [Homo
sapiens]
Length = 319
Score = 214 bits (545), Expect = 7e-56
Identities = 119/283 (42%), Positives = 163/283 (57%), Gaps = 30/283 (10%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQ 71
IL ++Q+++ SN+Y E P + A P + K + + +P ++ + H
Sbjct: 38 ILSLDQIKAIRGSNEYTEGPSVVKRPA---PRTAPRQEKHERTHEIIPINVNNNYEHRHT 94
Query: 72 LQP-------------LPQHLSQSSIASSMSHSTTASDQRLLASITPS---PSGQS--II 113
L + S S ASS S+S+ +S+Q LL P+ P +S I
Sbjct: 95 SHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAI 154
Query: 114 RTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQR 173
RTQP + G+LK + Q H FICE+CG+CKC CTA R LPSC CN++
Sbjct: 155 RTQPKQLIVDDLKGSLKEDLTQ-------HKFICEQCGKCKCGECTAPRTLPSCLACNRQ 207
Query: 174 CLCSAESLLDYGTCLCCVKGLFYHCSTDDE-DNCADEPCSCGPSSCFVRWAAMSLISLFL 232
CLCSAES+++YGTC+C VKG+FYHCS DDE D+ +D PCSC S C R+ M +SLFL
Sbjct: 208 CLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLFL 267
Query: 233 PCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISS 275
PCL CY P +GCL LC++ YD + RPGCRCK ++NTV K+ S
Sbjct: 268 PCLLCYPPAKGCLKLCRRCYDWIHRPGCRCK-NSNTVYCKLES 309
>gi|189571671 sprouty-related protein with EVH-1 domain 2 isoform b
[Homo sapiens]
Length = 415
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 105 PSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPL 164
P G S+I+TQP G + K + E+S +F EE R C
Sbjct: 277 PKGRGGSVIKTQPSRGKSRRR----KEDGERSRCVYCRDMFNHEENRRGHC--------- 323
Query: 165 PSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS---CFVR 221
Q S + + +C+ C + YHC +D E + D PCSC S C +R
Sbjct: 324 -------QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFC-LR 374
Query: 222 WAAMSLISLFLPCLCCYLPTRGCLH 246
W A+ +S PC+CCYLP R C H
Sbjct: 375 WMALIALSFLAPCMCCYLPLRACYH 399
>gi|189571669 sprouty-related protein with EVH-1 domain 2 isoform a
[Homo sapiens]
Length = 418
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 105 PSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPL 164
P G S+I+TQP G + K + E+S +F EE R C
Sbjct: 280 PKGRGGSVIKTQPSRGKSRRR----KEDGERSRCVYCRDMFNHEENRRGHC--------- 326
Query: 165 PSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS---CFVR 221
Q S + + +C+ C + YHC +D E + D PCSC S C +R
Sbjct: 327 -------QDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTD-PCSCDTSDEKFC-LR 377
Query: 222 WAAMSLISLFLPCLCCYLPTRGCLH 246
W A+ +S PC+CCYLP R C H
Sbjct: 378 WMALIALSFLAPCMCCYLPLRACYH 402
>gi|22749221 sprouty-related protein 1 with EVH-1 domain [Homo
sapiens]
Length = 444
Score = 68.9 bits (167), Expect = 5e-12
Identities = 47/146 (32%), Positives = 70/146 (47%), Gaps = 23/146 (15%)
Query: 106 SPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLP 165
SP + +TQP + + K K + E+S + F EE R KC A P+
Sbjct: 304 SPKDSVVFKTQPSS-LKIKKSKRRKEDGERSRCVYCQERFNHEENVRGKCQD--APDPI- 359
Query: 166 SCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS---CFVRW 222
+RC+ +C+ C + + YHC +D E + +D PCSC S C +RW
Sbjct: 360 ------KRCIYQV-------SCMLCAESMLYHCMSDSEGDFSD-PCSCDTSDDKFC-LRW 404
Query: 223 AAMSLISLFLPCLCCYLPTRGCLHLC 248
A+ +S +PC+CCY+P R C H C
Sbjct: 405 LALVALSFIVPCMCCYVPLRMC-HRC 429
>gi|110225353 sprouty-related, EVH1 domain containing 3 isoform a
[Homo sapiens]
Length = 410
Score = 67.0 bits (162), Expect = 2e-11
Identities = 29/61 (47%), Positives = 39/61 (63%), Gaps = 3/61 (4%)
Query: 186 TCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSC--FVRWAAMSLISLFLPCLCCYLPTRG 243
+CL C + L YHC +D E + +D PC+C P RWAA++ +SL +PCLCCY P R
Sbjct: 330 SCLWCAESLLYHCLSDAEGDFSD-PCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRA 388
Query: 244 C 244
C
Sbjct: 389 C 389
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 35.8 bits (81), Expect = 0.045
Identities = 37/128 (28%), Positives = 46/128 (35%), Gaps = 30/128 (23%)
Query: 150 CGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADE 209
C RC C PC +C + CLC A + C C +G H D C
Sbjct: 2020 CTRCDCTPCGT----EACDPHSGHCLCKAG--VTGRRCDRCQEG---HFGFDGCGGC--R 2068
Query: 210 PCSCGPSS-----------CFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRP 258
PC+CGP++ C R M C C G L +QG + P
Sbjct: 2069 PCACGPAAEGSECHPQSGQCHCRPGTMG-----PQCREC---APGYWGLPEQGCRRCQCP 2120
Query: 259 GCRCKRHT 266
G RC HT
Sbjct: 2121 GGRCDPHT 2128
Score = 35.4 bits (80), Expect = 0.058
Identities = 31/106 (29%), Positives = 36/106 (33%), Gaps = 41/106 (38%)
Query: 147 CEECGRCKCVP------CTAARP----LPSCWLCNQRCLCSAESLLDY-----GTCLC-- 189
C+E GRC C P C RP P+C Q C C LD G C C
Sbjct: 599 CDEAGRCLCQPEFAGPHCDRCRPGYHGFPNC----QACTCDPRGALDQLCGAGGLCRCRP 654
Query: 190 ---------CVKGLF-------YHCSTDDEDNCADEP----CSCGP 215
C G HCS + + A +P CSC P
Sbjct: 655 GYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRP 700
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 35.0 bits (79), Expect = 0.076
Identities = 53/223 (23%), Positives = 79/223 (35%), Gaps = 24/223 (10%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQA-LSSPSLIVQTHKSDWS--LATMPTSLPRSLSQ 68
I P + ST E+P P ++ +S+ L + T K S T+PT P ++S
Sbjct: 908 ISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP-TIST 966
Query: 69 CHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPS----GQSIIRTQPGAGVHPK 124
P + + + + T ++L A P PS G + + P A P
Sbjct: 967 EKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPM 1026
Query: 125 ADGALKGEAEQSAGHPSEHLFICEECGR---CKCVPCTAARPLPSCW-LCNQRCLCSAES 180
L G S C R C C P + P PSC LC + C+C+
Sbjct: 1027 TSVIL-GTTTTSRSSTER----CPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGF 1080
Query: 181 L------LDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS 217
L + +C C +Y + E C C P S
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGS 1123
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 35.0 bits (79), Expect = 0.076
Identities = 53/223 (23%), Positives = 79/223 (35%), Gaps = 24/223 (10%)
Query: 12 ILPIEQLRSTHASNDYVERPPAPCKQA-LSSPSLIVQTHKSDWS--LATMPTSLPRSLSQ 68
I P + ST E+P P ++ +S+ L + T K S T+PT P ++S
Sbjct: 908 ISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP-TIST 966
Query: 69 CHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPS----GQSIIRTQPGAGVHPK 124
P + + + + T ++L A P PS G + + P A P
Sbjct: 967 EKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPM 1026
Query: 125 ADGALKGEAEQSAGHPSEHLFICEECGR---CKCVPCTAARPLPSCW-LCNQRCLCSAES 180
L G S C R C C P + P PSC LC + C+C+
Sbjct: 1027 TSVIL-GTTTTSRSSTER----CPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGF 1080
Query: 181 L------LDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSS 217
L + +C C +Y + E C C P S
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGS 1123
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 34.7 bits (78), Expect = 0.100
Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 12/117 (10%)
Query: 14 PIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQLQ 73
P + RS S D R + SS S +S WSL+ S RSL++
Sbjct: 465 PRRRSRSRSHSGDRYRRGGRGLRHHSSSRS------RSSWSLSP---SRSRSLTRSRSHS 515
Query: 74 PLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAGVHPKADGALK 130
P P S + S S S + + ++L G+ + +T+P AG K GA K
Sbjct: 516 PSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAG---KETGAAK 569
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 34.3 bits (77), Expect = 0.13
Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 21/102 (20%)
Query: 23 ASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQLQPLPQHLSQS 82
A++ + PP P K +S L V K D AT P LPR+ S PLP
Sbjct: 940 AASPHSSPPPLPAK---ASRQLQVYRSKMDGE-ATSP--LPRTRSG-----PLP------ 982
Query: 83 SIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAGVHPK 124
S S S+++S Q +A++ SPS +S + TQ G G P+
Sbjct: 983 ----SSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 34.3 bits (77), Expect = 0.13
Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 21/102 (20%)
Query: 23 ASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQLQPLPQHLSQS 82
A++ + PP P K +S L V K D AT P LPR+ S PLP
Sbjct: 940 AASPHSSPPPLPAK---ASRQLQVYRSKMDGE-ATSP--LPRTRSG-----PLP------ 982
Query: 83 SIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAGVHPK 124
S S S+++S Q +A++ SPS +S + TQ G G P+
Sbjct: 983 ----SSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 33.9 bits (76), Expect = 0.17
Identities = 25/98 (25%), Positives = 35/98 (35%), Gaps = 11/98 (11%)
Query: 149 ECGRC--------KCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCST 200
+C RC C PC C CL + + + C C+ G +
Sbjct: 850 QCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHN-CERCLAGYYGDPII 908
Query: 201 DDEDNCADEPCSCGPSS--CFVRWAAMSLISLFLPCLC 236
D+C PC GP S F R ++L L C+C
Sbjct: 909 GSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 33.5 bits (75), Expect = 0.22
Identities = 38/129 (29%), Positives = 46/129 (35%), Gaps = 34/129 (26%)
Query: 153 CKCVPCTAARPLPSCWLCNQRCL---CSAESLLDYG---TCLCCVKGLFYHCSTDDEDNC 206
C C+P A P C CL C + D+ TC C +HC D D
Sbjct: 873 CSCLPGFAG---PRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPD-- 927
Query: 207 ADEPCSCGPSSCFVRWAAMSLISLFLPCLC--------CY-----LPTRGCLHLCQQGYD 253
C PSSCF + ++ F CLC C +R CLH G
Sbjct: 928 ------CSPSSCFNGGTCVDGVNSF-SCLCRPGYTGAHCQHEADPCLSRPCLH---GGVC 977
Query: 254 SLRRPGCRC 262
S PG RC
Sbjct: 978 SAAHPGFRC 986
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 33.5 bits (75), Expect = 0.22
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 7/81 (8%)
Query: 145 FICEECGRCKCVPCTAARP-LPSCWLCNQRCLCSAESLLDYGTCL------CCVKGLFYH 197
F+ +C C CT + L S C C C ++D GTC+ C GL Y
Sbjct: 335 FVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS 394
Query: 198 CSTDDEDNCADEPCSCGPSSC 218
+ E C + C G +C
Sbjct: 395 VGSKIEQECTECVCVGGVWNC 415
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 33.5 bits (75), Expect = 0.22
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 7/81 (8%)
Query: 145 FICEECGRCKCVPCTAARP-LPSCWLCNQRCLCSAESLLDYGTCL------CCVKGLFYH 197
F+ +C C CT + L S C C C ++D GTC+ C GL Y
Sbjct: 335 FVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS 394
Query: 198 CSTDDEDNCADEPCSCGPSSC 218
+ E C + C G +C
Sbjct: 395 VGSKIEQECTECVCVGGVWNC 415
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo
sapiens]
Length = 2250
Score = 33.5 bits (75), Expect = 0.22
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 7/81 (8%)
Query: 145 FICEECGRCKCVPCTAARP-LPSCWLCNQRCLCSAESLLDYGTCL------CCVKGLFYH 197
F+ +C C CT + L S C C C ++D GTC+ C GL Y
Sbjct: 335 FVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS 394
Query: 198 CSTDDEDNCADEPCSCGPSSC 218
+ E C + C G +C
Sbjct: 395 VGSKIEQECTECVCVGGVWNC 415
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 33.5 bits (75), Expect = 0.22
Identities = 26/80 (32%), Positives = 29/80 (36%), Gaps = 15/80 (18%)
Query: 149 ECGRCKCVPC-TAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCA 207
E C C PC T R P LC+ CLC C C + C DE NC
Sbjct: 2 ETAMCVCCPCCTWQRCCPQ--LCS--CLCCKFIFTSERNCTC------FPCPYKDERNCQ 51
Query: 208 DEPCSCGPSS----CFVRWA 223
C+C S C WA
Sbjct: 52 FCHCTCSESPNCHWCCCSWA 71
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 33.1 bits (74), Expect = 0.29
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 25/120 (20%)
Query: 147 CEECGRCKCVPCTAARPLPSC---WL---CNQRCLCSAESLLDYGTCLCCVKGLFYHCST 200
C + GRC + RP SC W C R CSA ++ G CL + HC
Sbjct: 127 CSKRGRCHIQ--ASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPP 184
Query: 201 DDEDNCAD---EPCSCGPSSCFVRWAAMSLISLFLPCLC--------CYL-----PTRGC 244
E + + C P C + + + F CLC C L P RGC
Sbjct: 185 GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSF-QCLCPVGQEGPRCELRAGPCPPRGC 243
>gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Homo
sapiens]
Length = 420
Score = 33.1 bits (74), Expect = 0.29
Identities = 33/120 (27%), Positives = 40/120 (33%), Gaps = 11/120 (9%)
Query: 148 EECGRCKCVPCTAARPLPS--CWLCNQRCL-CSAESLLDYGTCLCCVKG-LFYHCSTDDE 203
E CG+C A R C C C CS + CL C KG +H D
Sbjct: 190 EACGQCGLGYFEAERNASHLVCSACFGPCARCSGP---EESNCLQCKKGWALHHLKCVDI 246
Query: 204 DNCADEPCSCGPSS-CFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRC 262
D C E +CG C + CL C G C GY + G +C
Sbjct: 247 DECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV---GSKC 303
>gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Homo
sapiens]
Length = 422
Score = 33.1 bits (74), Expect = 0.29
Identities = 33/120 (27%), Positives = 40/120 (33%), Gaps = 11/120 (9%)
Query: 148 EECGRCKCVPCTAARPLPS--CWLCNQRCL-CSAESLLDYGTCLCCVKG-LFYHCSTDDE 203
E CG+C A R C C C CS + CL C KG +H D
Sbjct: 190 EACGQCGLGYFEAERNASHLVCSACFGPCARCSGP---EESNCLQCKKGWALHHLKCVDI 246
Query: 204 DNCADEPCSCGPSS-CFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRC 262
D C E +CG C + CL C G C GY + G +C
Sbjct: 247 DECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV---GSKC 303
>gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Homo
sapiens]
Length = 420
Score = 33.1 bits (74), Expect = 0.29
Identities = 33/120 (27%), Positives = 40/120 (33%), Gaps = 11/120 (9%)
Query: 148 EECGRCKCVPCTAARPLPS--CWLCNQRCL-CSAESLLDYGTCLCCVKG-LFYHCSTDDE 203
E CG+C A R C C C CS + CL C KG +H D
Sbjct: 190 EACGQCGLGYFEAERNASHLVCSACFGPCARCSGP---EESNCLQCKKGWALHHLKCVDI 246
Query: 204 DNCADEPCSCGPSS-CFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRC 262
D C E +CG C + CL C G C GY + G +C
Sbjct: 247 DECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV---GSKC 303
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 33.1 bits (74), Expect = 0.29
Identities = 27/106 (25%), Positives = 34/106 (32%), Gaps = 16/106 (15%)
Query: 150 CGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDY-GTCLCCVKGLFYHCSTDDE-DNCA 207
CG C C C+ +P C C C Y C CC CS+ +C
Sbjct: 72 CGSCGCSQCSCCKPCCCSSGCGSSC-CQCSCCKPYCSQCSCCKP----CCSSSGRGSSCC 126
Query: 208 DEPC---SCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQ 250
C C S C S C C +R C+ +C Q
Sbjct: 127 QSSCCKPCCSSSGCGSSCCQSSC------CKPCCSQSRCCVPVCYQ 166
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 32.7 bits (73), Expect = 0.38
Identities = 32/103 (31%), Positives = 42/103 (40%), Gaps = 9/103 (8%)
Query: 10 QQILPIEQLRSTHASNDYVERPPAPCK-QALSSPSLIVQTHKSDWSLATMPTSLPRSL-- 66
Q L + S H ++ P+ Q L SL V T S A +PTSLP SL
Sbjct: 2416 QPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPA-LPTSLPSSLVP 2474
Query: 67 --SQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSP 107
+ L P QH S + ++ SH + L TPSP
Sbjct: 2475 PVTAAQFLTPPSQHSYSSPVDNTPSHQLQVPEHPFL---TPSP 2514
>gi|148886718 zinc finger, CCHC domain containing 4 [Homo sapiens]
Length = 513
Score = 32.7 bits (73), Expect = 0.38
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 140 PSEHLFICEECGRCKCVPCTAARPLPS--CWLCNQRCLCSAESLLDYGTC-LC--CVKGL 194
P + + E G C PC L + C LCN C+++ + C LC CVK
Sbjct: 365 PPNKIILPTEEGYRFCSPCQRYVSLENQHCELCNS---CTSKDGRKWNHCFLCKKCVKPS 421
Query: 195 FYHCSTDDEDNCADEPCSCGPSSCFV 220
+ HCS + D C CF+
Sbjct: 422 WIHCSICNHCAVPDHSCEGPKHGCFI 447
>gi|123173777 keratin associated protein 5-8 [Homo sapiens]
Length = 187
Score = 32.7 bits (73), Expect = 0.38
Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 28/118 (23%)
Query: 147 CEECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCC--VKGLFYHC--STDD 202
C CG CVP +P+ C C CS +C C KG C S D
Sbjct: 21 CGGCGSSCCVPICCCKPV---CCCVPACSCS--------SCGSCGGSKGGRGSCGGSKGD 69
Query: 203 EDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGC 260
+C CG C S S + PC C + GC C Q S +P C
Sbjct: 70 CGSCGGSKGGCGSCGC-------SQCSCYKPCCC----SSGCGSSCCQ--SSCCKPCC 114
Score = 30.4 bits (67), Expect = 1.9
Identities = 29/114 (25%), Positives = 36/114 (31%), Gaps = 24/114 (21%)
Query: 150 CGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADE 209
CG C C C+ +P C C S+ CC CS+ +C
Sbjct: 80 CGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKP---CSCSSGCGSSCCQS 136
Query: 210 PC---SCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGC 260
C C SSC PC C + GC C Q S +P C
Sbjct: 137 SCCKPCCSQSSC------------CKPCCC----SSGCGSSCCQ--SSCCKPCC 172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.132 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,666,723
Number of Sequences: 37866
Number of extensions: 713993
Number of successful extensions: 5123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 4944
Number of HSP's gapped (non-prelim): 266
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.