Guide to the Human Genome
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Search of human proteins with 27477045

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27477045 mitochondrial malonyltransferase isoform b
precursor [Homo sapiens]
         (180 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27477045 mitochondrial malonyltransferase isoform b precursor...   359   e-100
gi|51243059 mitochondrial malonyltransferase isoform a precursor...   342   1e-94
gi|121949746 family with sequence similarity 132, member A [Homo...    30   1.5  
gi|13186302 calpain 10 isoform a [Homo sapiens]                        29   1.9  
gi|122937321 UNC homeobox [Homo sapiens]                               29   1.9  
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              29   2.5  
gi|38045915 pregnancy-associated plasma protein A preproprotein ...    29   2.5  
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]      29   2.5  
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]      29   2.5  
gi|122937480 Ras association (RalGDS/AF-6) domain family (N-term...    29   2.5  
gi|89353291 calpain 10 isoform c [Homo sapiens]                        28   3.3  
gi|21265043 ADAM metallopeptidase with thrombospondin type 1 mot...    28   4.3  
gi|73695936 ADAM metallopeptidase with thrombospondin type 1 mot...    28   4.3  
gi|21265034 ADAM metallopeptidase with thrombospondin type 1 mot...    28   4.3  
gi|41872631 fatty acid synthase [Homo sapiens]                         28   5.6  
gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]     27   7.3  
gi|4503811 fucosyltransferase 4 [Homo sapiens]                         27   9.5  
gi|4502805 chromogranin A precursor [Homo sapiens]                     27   9.5  
gi|239756193 PREDICTED: hypothetical protein [Homo sapiens]            27   9.5  
gi|239750725 PREDICTED: hypothetical protein XP_002347492 [Homo ...    27   9.5  
gi|239745029 PREDICTED: hypothetical protein XP_002343302 [Homo ...    27   9.5  
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]                 27   9.5  

>gi|27477045 mitochondrial malonyltransferase isoform b precursor
           [Homo sapiens]
          Length = 180

 Score =  359 bits (921), Expect = e-100
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG 60
           MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG
Sbjct: 1   MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG 60

Query: 61  QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC 120
           QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC
Sbjct: 61  QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC 120

Query: 121 QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGSTVSPEEFL 180
           QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGSTVSPEEFL
Sbjct: 121 QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGSTVSPEEFL 180


>gi|51243059 mitochondrial malonyltransferase isoform a precursor
           [Homo sapiens]
          Length = 390

 Score =  342 bits (877), Expect = 1e-94
 Identities = 171/171 (100%), Positives = 171/171 (100%)

Query: 1   MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG 60
           MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG
Sbjct: 1   MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG 60

Query: 61  QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC 120
           QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC
Sbjct: 61  QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC 120

Query: 121 QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEG 171
           QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEG
Sbjct: 121 QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEG 171


>gi|121949746 family with sequence similarity 132, member A [Homo
           sapiens]
          Length = 302

 Score = 29.6 bits (65), Expect = 1.5
 Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)

Query: 26  PVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVG 76
           P  PPGA+  AE L       +E    ATERR  G    LL  G G ++VG
Sbjct: 104 PPGPPGAEVTAETLLHEF---QELLKEATERRFSGLLDPLLPQGAGLRLVG 151


>gi|13186302 calpain 10 isoform a [Homo sapiens]
          Length = 672

 Score = 29.3 bits (64), Expect = 1.9
 Identities = 30/96 (31%), Positives = 37/96 (38%), Gaps = 20/96 (20%)

Query: 9   AWVRGLGASYRRGASSFPVPP--------PGAQGVAELLRDATGAEEEAPWAATERRMPG 60
           AWV+G  A   R  S FP  P        P    +A L R    A   A WA   R + G
Sbjct: 345 AWVKGQSAGGCRNNSGFPSNPKFWLRVSEPSEVYIAVLQRSRLHA---ADWAGRARALVG 401

Query: 61  QC----SVLLFPGQGSQVVGM-----GRGLLNYPRV 87
                 S    PG+  Q VG+      +  +N PRV
Sbjct: 402 DSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRV 437


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 1.9
 Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 3/45 (6%)

Query: 28  PPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGS 72
           PPP A+G       A+GA   AP    E   PG C    +P Q S
Sbjct: 250 PPPAAKGPGA---HASGAAGTAPAPPGEPPAPGTCDPAFYPSQRS 291


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 9/68 (13%)

Query: 13  GLGASYRRGASSFPVPPPG--AQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQ 70
           G G+  R G +  P PP G   +GV    R  +G E  +P        P   S    PG 
Sbjct: 177 GGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASP-------SPSSSSAGKTPGT 229

Query: 71  GSQVVGMG 78
           GS+  G G
Sbjct: 230 GSRNSGSG 237


>gi|38045915 pregnancy-associated plasma protein A preproprotein
           [Homo sapiens]
          Length = 1627

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 20  RGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQV 74
           RG  + P PPP   G  E +R     ++     ATE   P     L F G+G Q+
Sbjct: 53  RGRRASPPPPPPPGGAWEAVRVPRRRQQREARGATEEPSP-PSRALYFSGRGEQL 106


>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
          Length = 350

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 14 LGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCS 63
          +GA+   GA++ P PPP +      L  A  A EE P   +E   PG CS
Sbjct: 12 VGAAKTEGAAALPPPPPVS---PPALTPAPAAGEEGPAPLSETGAPG-CS 57


>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
          Length = 275

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 4/50 (8%)

Query: 14 LGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCS 63
          +GA+   GA++ P PPP +      L  A  A EE P   +E   PG CS
Sbjct: 12 VGAAKTEGAAALPPPPPVS---PPALTPAPAAGEEGPAPLSETGAPG-CS 57


>gi|122937480 Ras association (RalGDS/AF-6) domain family
          (N-terminal) member 10 [Homo sapiens]
          Length = 615

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 10/54 (18%)

Query: 15 GASYRRGASSFPVPPP---------GAQGVAELLRDATGAEEEAPWAATERRMP 59
          GA+  RGA   P PP          G +G + + R  T     APWA  ERR P
Sbjct: 11 GAARLRGAGLGPEPPALPATALGLGGGKGWSHVGRSKT-RRSRAPWAEPERREP 63


>gi|89353291 calpain 10 isoform c [Homo sapiens]
          Length = 517

 Score = 28.5 bits (62), Expect = 3.3
 Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 15/81 (18%)

Query: 9   AWVRGLGASYRRGASSFPVPP--------PGAQGVAELLRDATGAEEEAPWAATERRMPG 60
           AWV+G  A   R  S FP  P        P    +A L R    A   A WA   R + G
Sbjct: 345 AWVKGQSAGGCRNNSGFPSNPKFWLRVSEPSEVYIAVLQRSRLHA---ADWAGRARALVG 401

Query: 61  QC----SVLLFPGQGSQVVGM 77
                 S    PG+  Q VG+
Sbjct: 402 DSHTSWSPASIPGKHYQAVGL 422


>gi|21265043 ADAM metallopeptidase with thrombospondin type 1 motif,
           13 isoform 3 preproprotein [Homo sapiens]
          Length = 1340

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 41  DATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLL 82
           DAT A E+AP      R   Q + +  P  GS  V  GRGL+
Sbjct: 841 DATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLM 882


>gi|73695936 ADAM metallopeptidase with thrombospondin type 1 motif,
           13 isoform 2 preproprotein [Homo sapiens]
          Length = 1371

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 41  DATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLL 82
           DAT A E+AP      R   Q + +  P  GS  V  GRGL+
Sbjct: 872 DATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLM 913


>gi|21265034 ADAM metallopeptidase with thrombospondin type 1 motif,
           13 isoform 1 preproprotein [Homo sapiens]
          Length = 1427

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 17/42 (40%), Positives = 21/42 (50%)

Query: 41  DATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLL 82
           DAT A E+AP      R   Q + +  P  GS  V  GRGL+
Sbjct: 872 DATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLM 913


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 27.7 bits (60), Expect = 5.6
 Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 16/120 (13%)

Query: 44  GAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYA---AARRVLGY 100
           G  E     A ER +   CS     G G+Q  GMG  L+   R R+       A +  G 
Sbjct: 478 GGPEVQQVPAGERPLWFICS-----GMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGL 532

Query: 101 DLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLH--HLQPSVIENCVAAAGFSVGEFA 158
            + +L L   + T D  VH   ++    +  ++ L    L+P  I       G S+GE A
Sbjct: 533 KVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGI------VGHSLGEVA 586


>gi|114431216 tumor protein p53 inducible protein 13 [Homo sapiens]
          Length = 393

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 15/47 (31%), Positives = 19/47 (40%)

Query: 14  LGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG 60
           LG    R A  FP   PG+    + +    G E  AP   T   +PG
Sbjct: 211 LGPQPTRSALRFPSASPGSLKAKQSMAGIPGRESNAPSVPTVSLLPG 257


>gi|4503811 fucosyltransferase 4 [Homo sapiens]
          Length = 530

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 19/60 (31%), Positives = 25/60 (41%)

Query: 40 RDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLG 99
          R  +GA  E  WA   +  PG  S  L PG+  +      G  ++P    L A   R LG
Sbjct: 9  RKPSGAGWEKEWAEAPQEAPGAWSGRLGPGRSGRKGRAVPGWASWPAHLALAARPARHLG 68


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 2/65 (3%)

Query: 21  GASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPGQCSVLLFPGQGSQ--VVGMG 78
           GA    +P P  +  AE    A G EEE    AT    P       +PG  ++    G+ 
Sbjct: 148 GARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLS 207

Query: 79  RGLLN 83
           +GL++
Sbjct: 208 QGLVD 212


>gi|239756193 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 182

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 9/92 (9%)

Query: 28  PPPGAQGVAELLRDATGAEEEAPWAATERRMPG---------QCSVLLFPGQGSQVVGMG 78
           P P  +    L R  +GA  EA    T   M G         +CS+LL P    +     
Sbjct: 77  PCPSGKPRVHLQRTRSGAGAEAGGLPTRGSMRGCPFLGSSAAKCSLLLRPPSRGEASPWL 136

Query: 79  RGLLNYPRVRELYAAARRVLGYDLLELSLHGP 110
              + +P   +  A     LG  LLE +  GP
Sbjct: 137 PEFMTHPVHHQQLACVSGWLGTSLLEATCLGP 168


>gi|239750725 PREDICTED: hypothetical protein XP_002347492 [Homo
           sapiens]
          Length = 182

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 9/92 (9%)

Query: 28  PPPGAQGVAELLRDATGAEEEAPWAATERRMPG---------QCSVLLFPGQGSQVVGMG 78
           P P  +    L R  +GA  EA    T   M G         +CS+LL P    +     
Sbjct: 77  PCPSGKPRVHLQRTRSGAGAEAGGLPTRGSMRGCPFLGSSAAKCSLLLRPPSRGEASPWL 136

Query: 79  RGLLNYPRVRELYAAARRVLGYDLLELSLHGP 110
              + +P   +  A     LG  LLE +  GP
Sbjct: 137 PEFMTHPVHHQQLACVSGWLGTSLLEATCLGP 168


>gi|239745029 PREDICTED: hypothetical protein XP_002343302 [Homo
           sapiens]
          Length = 182

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 9/92 (9%)

Query: 28  PPPGAQGVAELLRDATGAEEEAPWAATERRMPG---------QCSVLLFPGQGSQVVGMG 78
           P P  +    L R  +GA  EA    T   M G         +CS+LL P    +     
Sbjct: 77  PCPSGKPRVHLQRTRSGAGAEAGGLPTRGSMRGCPFLGSSAAKCSLLLRPPSRGEASPWL 136

Query: 79  RGLLNYPRVRELYAAARRVLGYDLLELSLHGP 110
              + +P   +  A     LG  LLE +  GP
Sbjct: 137 PEFMTHPVHHQQLACVSGWLGTSLLEATCLGP 168


>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/34 (41%), Positives = 16/34 (47%)

Query: 26   PVPPPGAQGVAELLRDATGAEEEAPWAATERRMP 59
            P PPP   G+ E L+ A      A  AA  RR P
Sbjct: 1045 PAPPPAQAGLQEALQAAGTRAGRAALAAAARRPP 1078


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,494,870
Number of Sequences: 37866
Number of extensions: 344647
Number of successful extensions: 984
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 974
Number of HSP's gapped (non-prelim): 24
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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