Guide to the Human Genome
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Search of human proteins with 27475985

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27475985 neurogenic differentiation 6 [Homo sapiens]
         (337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27475985 neurogenic differentiation 6 [Homo sapiens]               697   0.0  
gi|121114306 neurogenic differentiation 1 [Homo sapiens]              310   2e-84
gi|98986461 neurogenic differentiation 2 [Homo sapiens]               301   4e-82
gi|153792190 neurogenic differentiation 4 [Homo sapiens]              242   3e-64
gi|68989258 neurogenin 3 [Homo sapiens]                                87   2e-17
gi|38455396 neurogenin 1 [Homo sapiens]                                85   8e-17
gi|31077092 neurogenin 2 [Homo sapiens]                                82   9e-16
gi|4885075 atonal homolog 1 [Homo sapiens]                             77   3e-14
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    72   9e-13
gi|21553337 atonal homolog 7 [Homo sapiens]                            71   2e-12
gi|23097242 nephew of atonal 3 [Homo sapiens]                          70   2e-12
gi|226498192 atonal homolog 8 [Homo sapiens]                           63   3e-10
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    62   6e-10
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    60   3e-09
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    59   6e-09
gi|38202237 transcription factor 21 [Homo sapiens]                     59   8e-09
gi|38202239 transcription factor 21 [Homo sapiens]                     59   8e-09
gi|17981708 twist homolog 2 [Homo sapiens]                             57   2e-08
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    57   2e-08
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo...    57   2e-08
gi|148922889 scleraxis homolog B [Homo sapiens]                        55   7e-08
gi|186972126 scleraxis homolog A [Homo sapiens]                        55   7e-08
gi|116805332 musculin [Homo sapiens]                                   55   7e-08
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]      54   2e-07
gi|4507741 twist [Homo sapiens]                                        51   2e-06
gi|157739932 mesogenin 1 [Homo sapiens]                                50   3e-06
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]     49   5e-06
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    49   6e-06
gi|5031943 nescient helix loop helix 1 [Homo sapiens]                  49   6e-06
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    49   8e-06

>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score =  697 bits (1800), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MLTLPFDESVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRAPGEETEKEE 60
           MLTLPFDESVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRAPGEETEKEE
Sbjct: 1   MLTLPFDESVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRAPGEETEKEE 60

Query: 61  EEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKV 120
           EEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKV
Sbjct: 61  EEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKV 120

Query: 121 VPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGC 180
           VPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGC
Sbjct: 121 VPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGC 180

Query: 181 LQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELTTPPGHGTLDNSKSMKPYNYCSAY 240
           LQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELTTPPGHGTLDNSKSMKPYNYCSAY
Sbjct: 181 LQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELTTPPGHGTLDNSKSMKPYNYCSAY 240

Query: 241 ESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPL 300
           ESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPL
Sbjct: 241 ESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPL 300

Query: 301 GQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN 337
           GQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN
Sbjct: 301 GQGAMFRLPTDSHFPYDLHLRSQSLTMQDELNAVFHN 337


>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
          Length = 356

 Score =  310 bits (793), Expect = 2e-84
 Identities = 179/359 (49%), Positives = 232/359 (64%), Gaps = 26/359 (7%)

Query: 2   LTLPFDESVVM--PESQMCRKFSREC----EDQKQIKKPESFSKQIVLRGKSIKRAPGEE 55
           +T  + ES +M  P+ Q    ++ EC    +++ +  K E   + +     S++    EE
Sbjct: 1   MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEE 60

Query: 56  TEKE--EEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDA 113
            E E  EEEE+ EEED++  P+RRG +KKK TK RLER K RR +ANARERNRMHGLN A
Sbjct: 61  DEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA 120

Query: 114 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPT 173
           LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR GK PDL++FVQ LCKGLSQPT
Sbjct: 121 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT 180

Query: 174 TNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTF--YP-PYHSPELTTPPGHGTLDNSK- 229
           TNLVAGCLQLN R+FL  Q  +   H  +  ++F  +P  Y SP L +PP +GT+D+S  
Sbjct: 181 TNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPP-YGTMDSSHV 239

Query: 230 ---SMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYN 286
                 P+ Y +A E F+ES   +C SP F+GPLS PP++ NG FS K E + ++ KNY 
Sbjct: 240 FHVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLS-PPLSINGNFSFKHEPSAEFEKNYA 298

Query: 287 YGMHYCAVPPRGPLGQGAMF--------RLPTDSHFPYDLHLRSQSLTMQDELNAVFHN 337
           + MHY A    G    G++F         +P D+   +D H   + + M  +LNA+FH+
Sbjct: 299 FTMHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERV-MSAQLNAIFHD 356


>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
          Length = 382

 Score =  301 bits (772), Expect = 4e-82
 Identities = 172/333 (51%), Positives = 218/333 (65%), Gaps = 30/333 (9%)

Query: 34  PESFSKQIVLRGKSIKRAPGEETEKEEE---EEDREEEDENGL-------PRRRGLRKKK 83
           P   +K + LRG+    A   E ++E E   EE+ EEE+E GL       P++RG +K+K
Sbjct: 51  PARAAKPVPLRGEEGTEATLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRK 110

Query: 84  TTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYI 143
            TK RLER K RRQ+ANARERNRMH LN ALDNLRKVVPCYSKTQKLSKIETLRLAKNYI
Sbjct: 111 MTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYI 170

Query: 144 WALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAA---HHT 200
           WALSEILR GKRPDL+++VQ LCKGLSQPTTNLVAGCLQLN+R+FL  QG + A   H +
Sbjct: 171 WALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGS 230

Query: 201 RSPYSTFYPPYHSPELTTP--PGHGTLDN--SKSMKPYNYCSAYESFYES-----TSPEC 251
             P++    PY    L        G L    + +++ + YC+AYE+ Y +      SP+ 
Sbjct: 231 GGPFAMHPYPYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDY 290

Query: 252 ASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCAVPPRGPLGQGAMF----- 306
            S ++EGPLS PP+  NG FSLKQ+ + D+ K+Y+Y MHY A+P   P G G +F     
Sbjct: 291 NSSEYEGPLS-PPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAV 349

Query: 307 --RLPTDSHFPYDLHLRSQSLTMQDELNAVFHN 337
              + +++   YD+HL      M +ELNA FHN
Sbjct: 350 RGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN 382


>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
          Length = 331

 Score =  242 bits (618), Expect = 3e-64
 Identities = 136/266 (51%), Positives = 177/266 (66%), Gaps = 8/266 (3%)

Query: 54  EETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDA 113
           EE +  EEEE+ EE+ E   P+RRG +KKK TK RLER + RR +ANARER RMHGLNDA
Sbjct: 49  EEHDSIEEEEEEEEDGEK--PKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDA 106

Query: 114 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPT 173
           LDNLR+V+PCYSKTQKLSKIETLRLA+NYIWALSE+L  G+ P+   FV+ LCKGLSQPT
Sbjct: 107 LDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKGLSQPT 166

Query: 174 TNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPPYHSPELTTPPGHGTLDNSKSMKP 233
           +NLVAGCLQL  +S L+ +  + +    S  S     Y SP L +PP      +   +KP
Sbjct: 167 SNLVAGCLQLGPQSVLLEKHEDKSPICDSAISVHNFNYQSPGLPSPPYGHMETHLLHLKP 226

Query: 234 YNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYNYGMHYCA 293
             + S  ES + S  P+C++P +EGPL+ PP++ +G FSLKQ+ + D  K+Y++  HY  
Sbjct: 227 QVFKSLGESSFGSHLPDCSTPPYEGPLT-PPLSISGNFSLKQDGSPDLEKSYSFMPHY-- 283

Query: 294 VPPRGPLGQGAMFRLPTDSHFP-YDL 318
             P   L  G +   P  +  P YD+
Sbjct: 284 --PSSSLSSGHVHSTPFQAGTPRYDV 307


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 52/107 (48%), Positives = 65/107 (60%), Gaps = 5/107 (4%)

Query: 51  APGEETEKEEEEEDREEEDENGLPR----RRGLRKKKTTKLRLERVK-FRRQEANARERN 105
           AP   T       + EE    G PR    RRG R +  ++L L + +  RR++AN RERN
Sbjct: 35  APPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERN 94

Query: 106 RMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRI 152
           RMH LN ALD LR V+P +    KL+KIETLR A NYIWAL++ LRI
Sbjct: 95  RMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRI 141


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 85.1 bits (209), Expect = 8e-17
 Identities = 45/86 (52%), Positives = 57/86 (66%)

Query: 67  EEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSK 126
           ++DE    RRRG  + ++  L     + RR +AN RERNRMH LN ALD LR V+P +  
Sbjct: 65  QDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPD 124

Query: 127 TQKLSKIETLRLAKNYIWALSEILRI 152
             KL+KIETLR A NYIWAL+E LR+
Sbjct: 125 DTKLTKIETLRFAYNYIWALAETLRL 150


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 81.6 bits (200), Expect = 9e-16
 Identities = 43/79 (54%), Positives = 56/79 (70%), Gaps = 1/79 (1%)

Query: 75  RRRGLRKKKTTKLRLERVK-FRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKI 133
           R R + +   T   ++R+K  RR +AN RERNRMH LN ALD LR+V+P + +  KL+KI
Sbjct: 92  RARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKI 151

Query: 134 ETLRLAKNYIWALSEILRI 152
           ETLR A NYIWAL+E LR+
Sbjct: 152 ETLRFAHNYIWALTETLRL 170


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 6/109 (5%)

Query: 45  GKSIKRAPGEETEKEE--EEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANAR 102
           G S  ++PG    +E+  + +     DE G  R+R    K+   ++    K RR  ANAR
Sbjct: 112 GASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQ----KQRRLAANAR 167

Query: 103 ERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 151
           ER RMHGLN A D LR V+P ++  +KLSK ETL++A+ YI ALSE+L+
Sbjct: 168 ERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQ 216


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 71.6 bits (174), Expect = 9e-13
 Identities = 51/125 (40%), Positives = 66/125 (52%), Gaps = 5/125 (4%)

Query: 50  RAPGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHG 109
           RAP +  E   E+   E++      RRRG       + R    +  R   NARER RMH 
Sbjct: 56  RAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHD 115

Query: 110 LNDALDNLRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCK 167
           LNDALD LR V+P       +KLSKI TL LAKNYI   ++ L   +R  L+ F+ N  +
Sbjct: 116 LNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFL-NQGQ 172

Query: 168 GLSQP 172
           GL+ P
Sbjct: 173 GLAAP 177


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 38/68 (55%), Positives = 47/68 (69%)

Query: 88  RLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALS 147
           RLE    RR  ANARER RM GLN A D LR+VVP + + +KLSK ETL++A +YI AL+
Sbjct: 34  RLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALT 93

Query: 148 EILRIGKR 155
            IL   +R
Sbjct: 94  RILAEAER 101


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 43/97 (44%), Positives = 59/97 (60%), Gaps = 2/97 (2%)

Query: 54  EETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDA 113
           EE E E ++ D EEE+E    R RG+      K +      +RQ AN RER RM  LN+A
Sbjct: 63  EEEECEVDQGDGEEEEEE--ERGRGVSLLGRPKRKRVITYAQRQAANIRERKRMFNLNEA 120

Query: 114 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 150
            D LR+ VP ++  ++LS+IETLRLA  YI  ++E+L
Sbjct: 121 FDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELL 157


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 35/82 (42%), Positives = 49/82 (59%)

Query: 68  EDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKT 127
           +D +  PR+R       +       + RR  ANARER R+H ++ A + LRK VPCYS  
Sbjct: 204 QDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYG 263

Query: 128 QKLSKIETLRLAKNYIWALSEI 149
           QKLSK+  LR+A NYI +L+ +
Sbjct: 264 QKLSKLAILRIACNYILSLARL 285


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 38/82 (46%), Positives = 47/82 (57%), Gaps = 8/82 (9%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGK 154
           RR E+N RER RMH LN+A   LR+V+P     +KLSKIETL LAKNYI +L+       
Sbjct: 76  RRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLT------- 128

Query: 155 RPDLLTFVQNLCKGLSQPTTNL 176
              +LT   +   GL  P   L
Sbjct: 129 -ATILTMSSSRLPGLEGPGPKL 149


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 45/120 (37%), Positives = 57/120 (47%), Gaps = 7/120 (5%)

Query: 93  KFRRQEANARERNRMHGLNDALDNLRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEIL 150
           K  R   NARER RMH LNDALD LR V+P       +KLSKI TL LAKNYI   ++ L
Sbjct: 241 KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 300

Query: 151 RIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTFYPP 210
                 ++   V  L +G +    +L +      A + L    G        P+S   PP
Sbjct: 301 E-----EMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPP 355


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 31/63 (49%), Positives = 41/63 (65%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGK 154
           +RQ ANARER+R   +N A   LR ++P     +KLSKIETLRLA +YI  L+ +L +G 
Sbjct: 73  QRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGD 132

Query: 155 RPD 157
             D
Sbjct: 133 SAD 135


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 10/126 (7%)

Query: 35  ESFSKQIVLRGKSIKRAPGEETEKEEEEEDREEEDENGLPRRR----GLRKKKTTK---- 86
           E   +  +L    +K    +E     E  +     ENG P++     G R+K  TK    
Sbjct: 10  EDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPL 69

Query: 87  --LRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIW 144
             +  E  + +R  ANARER RM  L+ A   L+  +P      KLSK++TLRLA +YI 
Sbjct: 70  SGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIA 129

Query: 145 ALSEIL 150
            L +IL
Sbjct: 130 HLRQIL 135


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 10/126 (7%)

Query: 35  ESFSKQIVLRGKSIKRAPGEETEKEEEEEDREEEDENGLPRRR----GLRKKKTTK---- 86
           E   +  +L    +K    +E     E  +     ENG P++     G R+K  TK    
Sbjct: 10  EDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRRKAPTKKSPL 69

Query: 87  --LRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIW 144
             +  E  + +R  ANARER RM  L+ A   L+  +P      KLSK++TLRLA +YI 
Sbjct: 70  SGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIA 129

Query: 145 ALSEIL 150
            L +IL
Sbjct: 130 HLRQIL 135


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 42/130 (32%), Positives = 65/130 (50%), Gaps = 16/130 (12%)

Query: 45  GKSIKRAPGEETEKEEEEEDRE--------------EEDENGLPRRRGLRKKKTTKLRLE 90
           G S   +P +     EEE +R+               ED +  P +RG +K   +    E
Sbjct: 4   GSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRG-KKGSPSAQSFE 62

Query: 91  RVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 150
            ++ +R  AN RER R   LN+A   LRK++P    + KLSKI+TL+LA  YI  L ++L
Sbjct: 63  ELQSQRILANVRERQRTQSLNEAFAALRKIIPTL-PSDKLSKIQTLKLAARYIDFLYQVL 121

Query: 151 RIGKRPDLLT 160
           +  +  + +T
Sbjct: 122 QSDEMDNKMT 131


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 30/72 (41%), Positives = 47/72 (65%), Gaps = 3/72 (4%)

Query: 80  RKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLA 139
           R++  ++  L+++   RQ AN RER RM  +NDA + LR  +P     ++LSK++TLRLA
Sbjct: 152 RRRVRSEAELQQL---RQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLA 208

Query: 140 KNYIWALSEILR 151
             YI  LSE+++
Sbjct: 209 IGYINFLSELVQ 220


>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
           sapiens]
          Length = 323

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 35/77 (45%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 81  KKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCY--SKTQKLSKIETLRL 138
           KK+ T+  L++++ +    N+RER RMH LN A+D LR+V+P       +KLSKI TL L
Sbjct: 98  KKQMTEPELQQLRLK---INSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154

Query: 139 AKNYIWALSEILRIGKR 155
           A+NYI  L+  L   KR
Sbjct: 155 ARNYILMLTNSLEEMKR 171


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 29/60 (48%), Positives = 39/60 (65%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGK 154
           +R  ANARER+R + +N A   LR ++P     +KLSKIETLRLA +YI  L  +L  G+
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 29/60 (48%), Positives = 39/60 (65%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGK 154
           +R  ANARER+R + +N A   LR ++P     +KLSKIETLRLA +YI  L  +L  G+
Sbjct: 76  QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 53/168 (31%), Positives = 70/168 (41%), Gaps = 33/168 (19%)

Query: 9   SVVMPESQMCRKFSRECEDQKQIKKPESFSKQIVLRGKSIKRA-PGEETEKEEEEEDREE 67
           SV  PE    R   RE         P   SK+  LRG     A P + +  EEE+ D EE
Sbjct: 5   SVSDPEEMELRGLQREY--------PVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEE 56

Query: 68  E--------DENGLPRRR----------------GLRKKKTTKLRLERVKFRRQEANARE 103
           E           G  R+R                G +         E  + +R  ANARE
Sbjct: 57  ERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARE 116

Query: 104 RNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 151
           R RM  L+ A   L+  +P      KLSK++TLRLA +YI  L ++L+
Sbjct: 117 RARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQ 164


>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
          Length = 272

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 34/77 (44%), Positives = 48/77 (62%), Gaps = 5/77 (6%)

Query: 81  KKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCY--SKTQKLSKIETLRL 138
           KK+ ++  L++++ +    N RER RMH LN A+D LR+V+P       +KLSKI TL L
Sbjct: 73  KKQLSEQDLQQLRLK---INGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLL 129

Query: 139 AKNYIWALSEILRIGKR 155
           A+NYI  L+  L   KR
Sbjct: 130 ARNYILMLTSSLEEMKR 146


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 28/62 (45%), Positives = 40/62 (64%), Gaps = 1/62 (1%)

Query: 90  ERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEI 149
           E ++ +R  AN RER R   LN+A   LRK++P    + KLSKI+TL+LA  YI  L ++
Sbjct: 104 EELQTQRVMANVRERQRTQSLNEAFAALRKIIPTL-PSDKLSKIQTLKLAARYIDFLYQV 162

Query: 150 LR 151
           L+
Sbjct: 163 LQ 164


>gi|157739932 mesogenin 1 [Homo sapiens]
          Length = 193

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 33/81 (40%), Positives = 50/81 (61%), Gaps = 4/81 (4%)

Query: 78  GLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVV-PCYS-KTQKLSKIET 135
           G + +K TK+R+     RR++A+ RE+ RM  L DAL  LR  + P YS + Q L+KI+T
Sbjct: 110 GPKAQKGTKVRMSVQ--RRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQT 167

Query: 136 LRLAKNYIWALSEILRIGKRP 156
           L+    YI  L+++L  G+ P
Sbjct: 168 LKYTIKYIGELTDLLNRGREP 188


>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
          Length = 271

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 30/63 (47%), Positives = 39/63 (61%), Gaps = 7/63 (11%)

Query: 96  RQEANARERNRMHGLNDALDNLRKVVPCYSKT-------QKLSKIETLRLAKNYIWALSE 148
           R++ N+RER RM  LN A+D LR+V+  YS         +KLSKI TL LA+NYI  L  
Sbjct: 107 RRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGS 166

Query: 149 ILR 151
            L+
Sbjct: 167 SLQ 169


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 26/56 (46%), Positives = 34/56 (60%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL 150
           RR  AN +ER R   +N A   LR+ +P      KLSKI+TLRLA +YI  L ++L
Sbjct: 100 RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLL 155


>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 17/101 (16%)

Query: 52  PGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLN 111
           PGE   K+ +   REE       RRR  R++ T K R             RER R+   N
Sbjct: 50  PGEPGRKDLQHLSREE-------RRR--RRRATAKYRTAHA--------TRERIRVEAFN 92

Query: 112 DALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRI 152
            A   LRK++P     +KLSKIE LRLA  YI  L+ +L +
Sbjct: 93  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 133


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 27/57 (47%), Positives = 34/57 (59%)

Query: 95  RRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 151
           RR   N+RER R   +N A   LRK++P +   +KLSK E LRLA  YI  L  +LR
Sbjct: 151 RRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLR 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,289,277
Number of Sequences: 37866
Number of extensions: 801162
Number of successful extensions: 14282
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 338
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 8260
Number of HSP's gapped (non-prelim): 3708
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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