Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 27436927
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436927 synoviolin 1 isoform b [Homo sapiens]
(617 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436927 synoviolin 1 isoform b [Homo sapiens] 1259 0.0
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 1253 0.0
gi|21071001 autocrine motility factor receptor [Homo sapiens] 123 4e-28
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 85 2e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 85 2e-16
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 82 2e-15
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 82 2e-15
gi|153792074 proline rich 12 [Homo sapiens] 81 3e-15
gi|160707881 formin 2 [Homo sapiens] 77 5e-14
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 77 5e-14
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 76 8e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 2e-13
gi|21314654 ring finger protein 139 [Homo sapiens] 73 7e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 72 1e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 72 2e-12
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 72 2e-12
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 72 2e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 70 4e-12
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 69 1e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 1e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 69 1e-11
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 69 1e-11
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 69 2e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 69 2e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 69 2e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 67 4e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 4e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 67 4e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 67 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 5e-11
>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
Length = 617
Score = 1259 bits (3258), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
Sbjct: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
Query: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
Sbjct: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
Query: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
Sbjct: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
Query: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
Sbjct: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
Query: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
Sbjct: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
Query: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
Sbjct: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
Query: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA 420
PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA
Sbjct: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA 420
Query: 421 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
Sbjct: 421 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
Query: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 540
FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
Sbjct: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 540
Query: 541 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 600
NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
Sbjct: 541 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 600
Query: 601 AELRRRRLQKLESPVAH 617
AELRRRRLQKLESPVAH
Sbjct: 601 AELRRRRLQKLESPVAH 617
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 1253 bits (3242), Expect = 0.0
Identities = 616/617 (99%), Positives = 616/617 (99%), Gaps = 1/617 (0%)
Query: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
Sbjct: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
Query: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
Sbjct: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
Query: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
Sbjct: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
Query: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
Sbjct: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
Query: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
Sbjct: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
Query: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
Sbjct: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
Query: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA 420
PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTS AALSRPSGA
Sbjct: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTS-AALSRPSGA 419
Query: 421 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
Sbjct: 420 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
Query: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 540
FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
Sbjct: 480 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 539
Query: 541 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 600
NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
Sbjct: 540 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 599
Query: 601 AELRRRRLQKLESPVAH 617
AELRRRRLQKLESPVAH
Sbjct: 600 AELRRRRLQKLESPVAH 616
>gi|21071001 autocrine motility factor receptor [Homo sapiens]
Length = 643
Score = 123 bits (309), Expect = 4e-28
Identities = 86/316 (27%), Positives = 143/316 (45%), Gaps = 26/316 (8%)
Query: 35 YLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSW-YAVTETCLAFT 93
YL S + VL A ++ L+ K++ + FG LR +E +HL ++ W + + F
Sbjct: 76 YLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFG 135
Query: 94 VFRDDFSPRFVAL---FTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMF---- 146
V V F L+FL L +DR +++ SP H R++SL+
Sbjct: 136 VLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLL 195
Query: 147 ----LLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSE 202
L + +H H++ A E ++ + ++YV+H DL E
Sbjct: 196 SCCGLAAVCSITGYTHGMHTLAFMAA--------ESLLVTVRTAHVILRYVIHLWDLNHE 247
Query: 203 NPWDNKAVYMLYTELFTGFIKVLL-YMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTD 261
W+ K Y+ YT+ + L M + +++ + + A +++ +R V
Sbjct: 248 GTWEGKGTYVYYTDFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQR 307
Query: 262 AIMSR----RAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLR 317
I R + NM + ATPEEL ++ C IC + M A++LPC H+FH SCLR
Sbjct: 308 RIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSM-QAARKLPCGHLFHNSCLR 366
Query: 318 SWFQRQQTCPTCRMDV 333
SW ++ +CPTCRM +
Sbjct: 367 SWLEQDTSCPTCRMSL 382
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 85.1 bits (209), Expect = 2e-16
Identities = 68/186 (36%), Positives = 75/186 (40%), Gaps = 49/186 (26%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPP------VPP 396
PPPP P D PP P PPP P PP P G+ PP + P + P PP +PP
Sbjct: 588 PPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSL-PGGTAISPPPPLSGDATIPP 644
Query: 397 PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA-------PEAG 449
PP E V PS S S P G A +A P GSA P G
Sbjct: 645 PPPLPEGVGIPSPS----SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 700
Query: 450 PA------------------------PGFPFPPPWMGMPLPPPFAF--PPMPVPPAGFAG 483
A PG P PPP MGMP PPPF F P PV P G
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP---FG 757
Query: 484 LTPEEL 489
LTP++L
Sbjct: 758 LTPKKL 763
Score = 63.9 bits (154), Expect = 4e-10
Identities = 57/168 (33%), Positives = 70/168 (41%), Gaps = 22/168 (13%)
Query: 330 RMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG 389
+ ++ S A + PP P+ PPAP PL P ++PP P PP
Sbjct: 550 KKEMASLSAAAITVPPSVPSRAPVPPAP---PL----PGDSGTIIPPPPAPGDSTTPPPP 602
Query: 390 PFPPVPPPPSSGEAV--APPS-TSAAALSRP---SGAATTTAAG--TSATAASATASGPG 441
P PP PPPP G +PPS A+S P SG AT + +S PG
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662
Query: 442 SGSAPEAGPAPG---FPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 486
+ P P PG P PPP PLP PP P P G AG+ P
Sbjct: 663 GTAIPPPPPLPGSARIPPPPP----PLPGSAGIPPPPPPLPGEAGMPP 706
Score = 33.9 bits (76), Expect = 0.45
Identities = 18/41 (43%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP 379
P PPPP P G PP PPP + PP P G P P
Sbjct: 715 PGIPPPPPFPGGPGIPP---PPPGMGMPPPPPFGFGVPAAP 752
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 85.1 bits (209), Expect = 2e-16
Identities = 68/186 (36%), Positives = 75/186 (40%), Gaps = 49/186 (26%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPP------VPP 396
PPPP P D PP P PPP P PP P G+ PP + P + P PP +PP
Sbjct: 597 PPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSL-PGGTAISPPPPLSGDATIPP 653
Query: 397 PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA-------PEAG 449
PP E V PS S S P G A +A P GSA P G
Sbjct: 654 PPPLPEGVGIPSPS----SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
Query: 450 PA------------------------PGFPFPPPWMGMPLPPPFAF--PPMPVPPAGFAG 483
A PG P PPP MGMP PPPF F P PV P G
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP---FG 766
Query: 484 LTPEEL 489
LTP++L
Sbjct: 767 LTPKKL 772
Score = 63.9 bits (154), Expect = 4e-10
Identities = 57/168 (33%), Positives = 70/168 (41%), Gaps = 22/168 (13%)
Query: 330 RMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG 389
+ ++ S A + PP P+ PPAP PL P ++PP P PP
Sbjct: 559 KKEMASLSAAAITVPPSVPSRAPVPPAP---PL----PGDSGTIIPPPPAPGDSTTPPPP 611
Query: 390 PFPPVPPPPSSGEAV--APPS-TSAAALSRP---SGAATTTAAG--TSATAASATASGPG 441
P PP PPPP G +PPS A+S P SG AT + +S PG
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
Query: 442 SGSAPEAGPAPG---FPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 486
+ P P PG P PPP PLP PP P P G AG+ P
Sbjct: 672 GTAIPPPPPLPGSARIPPPPP----PLPGSAGIPPPPPPLPGEAGMPP 715
Score = 33.9 bits (76), Expect = 0.45
Identities = 18/41 (43%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP 379
P PPPP P G PP PPP + PP P G P P
Sbjct: 724 PGIPPPPPFPGGPGIPP---PPPGMGMPPPPPFGFGVPAAP 761
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 81.6 bits (200), Expect = 2e-15
Identities = 62/183 (33%), Positives = 75/183 (40%), Gaps = 46/183 (25%)
Query: 339 PAQSPPPPEPADQGP-PPAPHPPP-------------------------------LLPQP 366
P PPP P +QGP PP H PP ++P P
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 367 PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAA 426
P P G PP P G P W PP PPPPSS A + P + + TTT+A
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP-----WQQNTTTTTTSA 536
Query: 427 GTSA-----TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 481
GT + +A A+ PG AP+ P PP + PLPP A PP P PP G
Sbjct: 537 GTGSIPPWQQQQAAAAASPG---APQMQGNPTMVPLPPGVQPPLPPG-APPPPPPPPPGS 592
Query: 482 AGL 484
AG+
Sbjct: 593 AGM 595
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/94 (32%), Positives = 35/94 (37%), Gaps = 27/94 (28%)
Query: 341 QSPPPPEPADQGPPPAPHP-----------------PPLLPQP------PNFPQ----GL 373
Q PPPP P+ P P PP Q P PQ
Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
Query: 374 LPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPP 407
+ P PPG+ P PP P PP PPPP S + PP
Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPP 599
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/302 (24%), Positives = 94/302 (31%), Gaps = 70/302 (23%)
Query: 320 FQR----QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLP 375
FQR Q RMD SL A+ P PA G P PL P P
Sbjct: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
Query: 376 PFPPGMF------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTS 429
P PP + P W GP P G P + P + T G
Sbjct: 354 P-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHP 412
Query: 430 ATAASATASGPGSGSAP---EAGP-APGFPFPPP---WMG-----------------MPL 465
P P GP PG PPP ++G MP
Sbjct: 413 MQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP 472
Query: 466 PPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYL 525
PP PP P PP+G P L ++Q +
Sbjct: 473 PPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPP---------------------- 508
Query: 526 TVLASLGPPRPATSVNST-----EETATTVVAAASSTSIPSSEATTPTPGASPPAPEMER 580
PP P++S+ S+ ++ TT +A + SIP + ASP AP+M+
Sbjct: 509 ------PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562
Query: 581 PP 582
P
Sbjct: 563 NP 564
Score = 36.2 bits (82), Expect = 0.092
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 523 QYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 582
+YL+++A LG SV ST ATT +A+A P++ A P P S + RPP
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPR---PAAPANNPPP-PSLMSTTQSRPP 367
Query: 583 APESVGTEEMPEDG 596
S +E P G
Sbjct: 368 WMNSGPSESRPYHG 381
Score = 33.9 bits (76), Expect = 0.45
Identities = 30/99 (30%), Positives = 36/99 (36%), Gaps = 13/99 (13%)
Query: 323 QQTCPTCRMDVLRASLPA-QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM 381
QQ T S+P Q A G P P ++P PP G+ PP PPG
Sbjct: 526 QQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP----GVQPPLPPGA 581
Query: 382 FPLWPPMGPF---PPVPPPPSSGEAVAPPSTSAAALSRP 417
P PP P +PP G PS + RP
Sbjct: 582 PPPPPPPPPGSAGMMIPPRGGDG-----PSHESEDFPRP 615
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 81.6 bits (200), Expect = 2e-15
Identities = 62/183 (33%), Positives = 75/183 (40%), Gaps = 46/183 (25%)
Query: 339 PAQSPPPPEPADQGP-PPAPHPPP-------------------------------LLPQP 366
P PPP P +QGP PP H PP ++P P
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 367 PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAA 426
P P G PP P G P W PP PPPPSS A + P + + TTT+A
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP-----WQQNTTTTTTSA 536
Query: 427 GTSA-----TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 481
GT + +A A+ PG AP+ P PP + PLPP A PP P PP G
Sbjct: 537 GTGSIPPWQQQQAAAAASPG---APQMQGNPTMVPLPPGVQPPLPPG-APPPPPPPPPGS 592
Query: 482 AGL 484
AG+
Sbjct: 593 AGM 595
Score = 49.7 bits (117), Expect = 8e-06
Identities = 45/147 (30%), Positives = 50/147 (34%), Gaps = 43/147 (29%)
Query: 341 QSPPPPEPADQGPPPAPHP-----------------PPLLPQP------PNFPQ----GL 373
Q PPPP P+ P P PP Q P PQ
Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
Query: 374 LPPFPPGMFPLWPPMGPFPPVPPPP-SSGEAVAPPSTSAAALSRPSGAATTTAAGTSATA 432
+ P PPG+ P PP P PP PPPP S+G APP + PS
Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMD-PSN------------- 611
Query: 433 ASATASGPGSGSAPEAGPAPGFPFPPP 459
T G G P G P P PPP
Sbjct: 612 -FVTMMGMGVAGMPPFGMPPAPPPPPP 637
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
LP +PPPP P G + PP P PP P + G+ + PP G PP PPP
Sbjct: 577 LPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGM-PPFG-MPPAPPP 634
Query: 398 P 398
P
Sbjct: 635 P 635
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/302 (24%), Positives = 94/302 (31%), Gaps = 70/302 (23%)
Query: 320 FQR----QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLP 375
FQR Q RMD SL A+ P PA G P PL P P
Sbjct: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
Query: 376 PFPPGMF------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTS 429
P PP + P W GP P G P + P + T G
Sbjct: 354 P-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHP 412
Query: 430 ATAASATASGPGSGSAP---EAGP-APGFPFPPP---WMG-----------------MPL 465
P P GP PG PPP ++G MP
Sbjct: 413 MQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP 472
Query: 466 PPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYL 525
PP PP P PP+G P L ++Q +
Sbjct: 473 PPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPP---------------------- 508
Query: 526 TVLASLGPPRPATSVNST-----EETATTVVAAASSTSIPSSEATTPTPGASPPAPEMER 580
PP P++S+ S+ ++ TT +A + SIP + ASP AP+M+
Sbjct: 509 ------PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562
Query: 581 PP 582
P
Sbjct: 563 NP 564
Score = 36.2 bits (82), Expect = 0.092
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 523 QYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 582
+YL+++A LG SV ST ATT +A+A P++ A P P S + RPP
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPR---PAAPANNPPP-PSLMSTTQSRPP 367
Query: 583 APESVGTEEMPEDG 596
S +E P G
Sbjct: 368 WMNSGPSESRPYHG 381
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 80.9 bits (198), Expect = 3e-15
Identities = 90/294 (30%), Positives = 113/294 (38%), Gaps = 30/294 (10%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNF--PQGLLPPFPPGMFPLWPPMGP 390
+L P PP P P Q PPP P P P LP PP P PP PP + P PP P
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP-PPPLPPPPPPAMP 1510
Query: 391 FPPVPPPPSSGEAVAPPSTSAAAL--------SRPSGAA--TTTAAGTSATAASATASGP 440
PP PPPP++ APP AA +RP A TAA T A SG
Sbjct: 1511 SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESG- 1569
Query: 441 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPM-PVPPAGFAGLTPEELRALEGHERQH 499
G G E P + + L PP+ V A TPE ++ +RQ
Sbjct: 1570 GEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPE----IKDGQRQF 1625
Query: 500 LEAR-----LQSLRNIHTLLDAAMLQ-INQ--YLTVLASLGPPRPATSVNSTEETATTVV 551
+N + L L+ +N+ Y+ V A RP V + + V
Sbjct: 1626 CATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVS 1685
Query: 552 AAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRR 605
A SS P + A P P +P E+P PE MPE P+ L R
Sbjct: 1686 AGGSSAPPPKAPAPPPKP-ETPEKTTSEKP--PEQTPETAMPEPPAPEKPSLLR 1736
Score = 55.5 bits (132), Expect = 1e-07
Identities = 50/168 (29%), Positives = 53/168 (31%), Gaps = 48/168 (28%)
Query: 337 SLPAQSPPPPEPADQGPPPAPHPPPL----LPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
S P P P A GPPP P P P+PP LL PP P P P P
Sbjct: 1417 STPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPP-----LLEEKPPPTPPPAPTPQPQP 1471
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P PPPP +PP P P P
Sbjct: 1472 PPPPPPPQPALPSPP--------------------------------------PLVAPTP 1493
Query: 453 GFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHL 500
P PPP + P PP PP P PPA P E A E L
Sbjct: 1494 SSPPPPP-LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Score = 50.1 bits (118), Expect = 6e-06
Identities = 44/148 (29%), Positives = 52/148 (35%), Gaps = 20/148 (13%)
Query: 343 PPPPEPADQGPPPAPH--PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS 400
PP P D P P P +P PP P LP P P + PP PPP+
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG--LPSANSNGTPEPPLLEEKPPPTPPPAP 1465
Query: 401 GEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 460
PP P A + + T S P P P P P PPP
Sbjct: 1466 TPQPQPP---------PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP-PPPAMPSPPP- 1514
Query: 461 MGMPLPPPFAFPPMPVPPAGFAGLTPEE 488
PPP A P+ PP A +PE+
Sbjct: 1515 -----PPPPAAAPLAAPPEEPAAPSPED 1537
Score = 47.0 bits (110), Expect = 5e-05
Identities = 60/204 (29%), Positives = 78/204 (38%), Gaps = 45/204 (22%)
Query: 296 EEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPP 355
E ++GA LP + F +S S +Q + + R + +SL Q PP PA+ P
Sbjct: 129 ELFISGA--LPGSSTFPSSSALSAYQHPASFGS-RPFPVPSSLSLQDPPFSPPANGLLSP 185
Query: 356 ------APHPPPLLPQPPNFPQ----GLLPPFPPGMFPLW-PPMGPFPPVPPPPSSGEAV 404
P P +P F + G+L P G+ P PP P PP PPPP
Sbjct: 186 HDVLHLKPSQAPTVPSSLGFERLAGGGVLGP--AGLGPAQTPPYRPGPPDPPPP------ 237
Query: 405 APPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMP 464
R A +SA AA+A S P + A P P PPP +P
Sbjct: 238 ----------PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP----PPPERALP 283
Query: 465 LP---------PPFAFPPMPVPPA 479
P A PP P PPA
Sbjct: 284 RQDTVIKHYQRPASAQPPPPPPPA 307
Score = 43.1 bits (100), Expect = 7e-04
Identities = 75/278 (26%), Positives = 88/278 (31%), Gaps = 81/278 (29%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS 400
+SPPPP P Q P PH L P+ P +LPP PP + P P P P
Sbjct: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPL-VLPPPPPQLLPSVLSHAP-SPSPSASKV 819
Query: 401 GEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 460
G + P+T G P PPP
Sbjct: 820 GVHLLEPAT-----------------------------------------RDGAPQPPP- 837
Query: 461 MGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQH-LEARLQSLR-NIHTLLD--A 516
PPP PPMP+ LE H R H LE S R LD
Sbjct: 838 -----PPPPPPPPMPL--------------QLEAHLRSHGLEPAAPSPRLRPEESLDPPG 878
Query: 517 AMLQINQYLTVL------ASLGPPR-----PATSVNSTEETATTVVAAASSTSI--PSSE 563
AM ++ L L +GPP PA + S T TSI P S
Sbjct: 879 AMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSL 938
Query: 564 ATTPTPGASPPAPEMERPPAPESVGTEEMPED-GEPDA 600
P EM A + G PED G+P A
Sbjct: 939 LQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKA 976
Score = 40.8 bits (94), Expect = 0.004
Identities = 50/181 (27%), Positives = 58/181 (32%), Gaps = 33/181 (18%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHP----------PPLLPQPPNFPQGLLPPFPPGMFPL 384
R P PPPP P PPP P P P P P+ L P P M L
Sbjct: 829 RDGAPQPPPPPPPP----PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP-PGAMQEL 883
Query: 385 WPPMGPFPPVP------PPPSSGE--AVAPPSTSAAALSRPSGAATTTAAGTSATAASAT 436
+ P PP P PP S G+ A A S S P T+ +
Sbjct: 884 LGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEE 943
Query: 437 AS----------GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 486
S G + +AGP P G P PP P P P +G P
Sbjct: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003
Query: 487 E 487
E
Sbjct: 1004 E 1004
Score = 38.5 bits (88), Expect = 0.018
Identities = 34/128 (26%), Positives = 43/128 (33%), Gaps = 8/128 (6%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPP 393
+R S A++P + PP AP PPP P P+ PP P P PP
Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPAPPP----KPETPEKTTSEKPPEQTP--ETAMPEPP 1727
Query: 394 VPPPPSSGEAVAPPSTSAAAL--SRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA 451
P PS V RP T+ + S P + P+A P
Sbjct: 1728 APEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPT 1787
Query: 452 PGFPFPPP 459
PPP
Sbjct: 1788 KVKAEPPP 1795
Score = 32.3 bits (72), Expect = 1.3
Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 16/136 (11%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQ--GLLPPFPPGMFPLWPPMGPFP 392
+A P P PE PP P +P+PP P+ LL P G P
Sbjct: 1695 KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP-APEKPSLLRPVEKEKEKEKVTRGERP 1753
Query: 393 PVPPPPSSGEAVAP--------PSTSAAALSRPSGAAT-----TTAAGTSATAASATASG 439
+SG P P+TS +RP+ +ATA G
Sbjct: 1754 LRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGG 1813
Query: 440 PGSGSAPEAGPAPGFP 455
GS+ ++ +PG P
Sbjct: 1814 GPPGSSSDSESSPGAP 1829
Score = 32.0 bits (71), Expect = 1.7
Identities = 48/174 (27%), Positives = 58/174 (33%), Gaps = 63/174 (36%)
Query: 339 PAQSPP----PPEPADQGPPPAPHPPPLL-----------------PQPPNFPQGLLPPF 377
PAQ+PP PP+P PPP H P PQ NF G P
Sbjct: 221 PAQTPPYRPGPPDP----PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF-SGAAPGP 275
Query: 378 PPGMFPL----------WPPMGPFPPVPPPPS-------------------SGEAVAP-- 406
PP L P PP PPPP+ + A +P
Sbjct: 276 PPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLG 335
Query: 407 ---PSTSAAALSR--PSGA-ATTTAAGTSATAASATASGPGSGSAPEAGPAPGF 454
PS A S+ PSGA A + T AA +G G G +PG+
Sbjct: 336 GGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGY 389
Score = 32.0 bits (71), Expect = 1.7
Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 357 PHPPPLLPQPPNF-PQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAP 406
P+ PP LP N P GL+ P P PP P PP P G +P
Sbjct: 1012 PNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Score = 31.6 bits (70), Expect = 2.3
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 384 LWPPMGPFPPVPPP-PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGS 442
L PP+ P VPP P+ G PP+T A PSG A G +A + G G
Sbjct: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSG-----AFGLGGALEAAESEGLGL 1357
Query: 443 G 443
G
Sbjct: 1358 G 1358
Score = 31.2 bits (69), Expect = 2.9
Identities = 23/84 (27%), Positives = 28/84 (33%), Gaps = 10/84 (11%)
Query: 395 PPPPSS----------GEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGS 444
PPPP S G A A + A+ G A + A G G G
Sbjct: 406 PPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQ 465
Query: 445 APEAGPAPGFPFPPPWMGMPLPPP 468
A + AP + PP PPP
Sbjct: 466 AQDLSKAPSYSGGPPQPPSGPPPP 489
Score = 30.8 bits (68), Expect = 3.8
Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 15/168 (8%)
Query: 442 SGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPEELRALEGHERQHL 500
+G P P P P G+ PP A P +P PP+G GL ALE E + L
Sbjct: 1301 AGLTPPLSPPKSVPPSVPARGLQPQPP-ATPAVPHPPPSGAFGLG----GALEAAESEGL 1355
Query: 501 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 560
S LD ++ + L L S SV + ++ +A S+ P
Sbjct: 1356 GLGCPSPCK---RLDE---ELKRNLETLPSFSSDE-EDSVAKNRDLQESISSAISALDDP 1408
Query: 561 --SSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRR 606
+ T TP P AP P P G +G P+ L +
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK 1456
Score = 30.4 bits (67), Expect = 5.0
Identities = 88/408 (21%), Positives = 122/408 (29%), Gaps = 131/408 (32%)
Query: 339 PAQSPPPPEPADQGPPPA-----PHPPPLL------------PQPPNFPQGLLPPFP--- 378
P+ S PP+P PPP + P L P P QGL P
Sbjct: 473 PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLS 532
Query: 379 ------PGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAG---TS 429
P + GP +S + P S A RP G + A G +S
Sbjct: 533 YSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSS 592
Query: 430 ATAASATASGPGSGS-APEAGPAPGFPFPPPWMGMPLPPP-------------FAFPPMP 475
A++ + PG+GS A AG G + P PP P P
Sbjct: 593 VLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSP 652
Query: 476 VPPAGFAGL------------------------TPEELRALEGHERQHLEARLQSLRNIH 511
+G GL TP EL A E +R HL++ +++ ++
Sbjct: 653 PRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYEL-AKEDPQRYHLQSVIRTSASLD 711
Query: 512 TLLDAAM-------------------------LQINQYLTVLASLG------PPRPATSV 540
AA+ + Y LG PP P +
Sbjct: 712 EGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTA 771
Query: 541 NSTEETATTVVAAASSTSIP--------------SSEATTPTPGAS-------------- 572
ST+ T ++ A +P S A +P+P AS
Sbjct: 772 QSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDG 831
Query: 573 ----PPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 616
PP P PP P + EP A R R + L+ P A
Sbjct: 832 APQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA 879
Score = 30.4 bits (67), Expect = 5.0
Identities = 31/104 (29%), Positives = 34/104 (32%), Gaps = 38/104 (36%)
Query: 348 PADQGPP-----PAPHPPPLLPQPPNFPQ------------GLLPPFPP----------- 379
P D+G P P P PP P P P GL P PP
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 380 GMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATT 423
G+ P PP PPPP PP A S P G T+
Sbjct: 1028 GLIQSGPHQAAPPPPPPPP-------PPPAPA---SEPKGGLTS 1061
Score = 29.6 bits (65), Expect = 8.6
Identities = 64/261 (24%), Positives = 95/261 (36%), Gaps = 30/261 (11%)
Query: 356 APHPPPLLPQPPNF-PQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAP-PSTSAAA 413
APHP L N P GL F G+ GP V S+ E+ P P SA++
Sbjct: 52 APHP--LQSYATNHHPAGLSGLFDTGLHHAGSA-GPDASVMNLISALESRGPQPGPSASS 108
Query: 414 L-SRPSGAATTTAAGTSA-TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF 471
L S+ + TA T T + + PGS + P + + P + P P P +
Sbjct: 109 LLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSL 168
Query: 472 ----PPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAML---QINQY 524
PP P G L+P ++ L+ + + + L L +L +
Sbjct: 169 SLQDPPFSPPANGL--LSPHDVLHLKPSQAPTVPSSL----GFERLAGGGVLGPAGLGPA 222
Query: 525 LTVLASLGPPRP-------ATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPE 577
T GPP P T N +++ AAA +S + PG PP PE
Sbjct: 223 QTPPYRPGPPDPPPPPRHLPTQFNLL-ASSSAAAAAAEQSSPQLYNFSGAAPG--PPPPE 279
Query: 578 MERPPAPESVGTEEMPEDGEP 598
P + + P +P
Sbjct: 280 RALPRQDTVIKHYQRPASAQP 300
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 77.0 bits (188), Expect = 5e-14
Identities = 53/148 (35%), Positives = 58/148 (39%), Gaps = 22/148 (14%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV---PPPPS 399
PPPP P PPP P P +P PP P +PP PP PP P P V PPPP
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 400 SGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGFPFPP 458
G + PP A P PG G P P G P PP
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPL------------------PGVGIPPPPPLPGVGIPPPP 1199
Query: 459 PWMGMPLPPPFAFPPMPVPPAGFAGLTP 486
P G +PPP P M +PPA L P
Sbjct: 1200 PLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Score = 76.6 bits (187), Expect = 6e-14
Identities = 55/158 (34%), Positives = 62/158 (39%), Gaps = 17/158 (10%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV---PPPPS 399
PPPP P PPP P P +P PP P +PP PP PP P P PPPP
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 400 SGEAVAPPSTSAAALSRP----SGAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGF 454
G + PP A P GA PG+G P P G
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1063
Query: 455 PFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 486
P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1064 PPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1098
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/169 (34%), Positives = 67/169 (39%), Gaps = 28/169 (16%)
Query: 343 PPPPEPADQGPPPAPHP-------PPL----LPQPPNFPQGLLPPFPP---GMFPLWPPM 388
PPPP P PPP P P PPL +P PP P +PP PP PL PP+
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970
Query: 389 --GPFPPVPPPPSSGEAVAPPSTSAAALSRP--SGAATTTAAGTSATAASATASGPGSGS 444
PP PP P +G PP A P GA PG+G
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
Query: 445 APEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 486
P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1076
Score = 75.5 bits (184), Expect = 1e-13
Identities = 52/151 (34%), Positives = 60/151 (39%), Gaps = 14/151 (9%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV---PPPPS 399
PPPP P PPP P P +P PP P +PP PP PP P P PPPP
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 400 SGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGFPFPP 458
G + PP GA PG+G P P G P PP
Sbjct: 1125 PGAGIPPPPPL-------PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
Query: 459 PWMGMPLPPPFAFPPM---PVPPAGFAGLTP 486
P G+ +PPP P + P PP AG+ P
Sbjct: 1178 PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Score = 73.2 bits (178), Expect = 7e-13
Identities = 60/174 (34%), Positives = 67/174 (38%), Gaps = 28/174 (16%)
Query: 338 LPAQSPPPPEP---ADQGPPP------APHPPPL----LPQPPNFPQGLLPPFPPGMFPL 384
LP PPP P A PPP P PPPL +P PP P +PP PP
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
Query: 385 WPPMGPFPPV---PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPG 441
PP P P V PPPP G + PP GA PG
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPL-------PGAGIPPPPPLPGVGIPPPPPLPG 1192
Query: 442 SGSAPEAG-PAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEG 494
G P P G P PPP GM +PP P P+PP G G+ P L + G
Sbjct: 1193 VGIPPPPPLPGAGIPPPPPLPGMGIPPA---PAPPLPPPG-TGIPPPPLLPVSG 1242
Score = 71.2 bits (173), Expect = 3e-12
Identities = 58/169 (34%), Positives = 70/169 (41%), Gaps = 23/169 (13%)
Query: 337 SLPAQSPPPPEPADQG-----PPPAPHPPPLLPQPPNFP-QGL--LPPFPPGMFPLWPPM 388
+LP+ + P P P QG PPP P P +P PP P G+ LPP P P PP+
Sbjct: 890 TLPSTAIPQPPPL-QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL 948
Query: 389 --GPFPPVPPPPSSGEAVAPPSTSAAALSRP--SGAATTTAAGTSATAASATASGPGSGS 444
PP PP P +G + PP A P GA PG+G
Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008
Query: 445 APEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 486
P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1054
Score = 70.9 bits (172), Expect = 3e-12
Identities = 50/151 (33%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 338 LPAQSPPPPEPADQG--PPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV- 394
LP PPP P PPP P P +P PP P +PP PP PP P P
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 395 --PPPPSSGEAVAPPSTSAAALSRP----SGAATTTAAGTSATAASATASGPGSGSAPEA 448
PPPP G + PP P GA PG+G P
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 449 G-PAPGFPFPPPWMGMPLPPPFAFPPMPVPP 478
P G P PPP G +PPP P +PP
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Score = 70.1 bits (170), Expect = 6e-12
Identities = 59/171 (34%), Positives = 67/171 (39%), Gaps = 31/171 (18%)
Query: 343 PPPPEPADQGPPPA------PHPPPLL------PQPPNFPQGLLPPFPP----GMFPLWP 386
PPPP P P P PPPL P PP P +PP PP G+ PL P
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
Query: 387 PMGPFPPVPPPPSSGEAV-APPSTSAAALSRP---SGAATTTAAGTSATAASATASGPGS 442
G P PPPP G A+ PP A + P GA PG+
Sbjct: 937 LPGAGIP-PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995
Query: 443 GSAPEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 486
G P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 996 GIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1043
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/158 (34%), Positives = 64/158 (40%), Gaps = 31/158 (19%)
Query: 338 LPAQSPPPPEPADQG--PPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV- 394
LP PPP P PPP P P +P PP P +PP PP PP P P V
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1183
Query: 395 --PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
PPPP G + PP A P PG G PAP
Sbjct: 1184 IPPPPPLPGVGIPPPPPLPGAGIPPPPPL------------------PGMG----IPPAP 1221
Query: 453 GFPFPPPWMGMPLPP--PFAFPPMPVPPAGFAGL-TPE 487
P PPP G+P PP P + PP+ +P G + L TP+
Sbjct: 1222 APPLPPPGTGIPPPPLLPVSGPPL-LPQVGSSTLPTPQ 1258
Score = 65.5 bits (158), Expect = 1e-10
Identities = 51/156 (32%), Positives = 60/156 (38%), Gaps = 16/156 (10%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM---GPFPPVPPP-PS 399
PPP P + P + P PP P +P P P PP+ PP PPP P
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 400 SGEAVAPPSTSAAALSRP--SGAATTTAAGTSATAASATASGPGSG-SAPEAGPAPGFPF 456
+G PP A L P GA A PG+G P P G P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
Query: 457 PPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 486
PPP G +PPP PP+ P PP AG+ P
Sbjct: 978 PPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1010
Score = 43.5 bits (101), Expect = 6e-04
Identities = 28/81 (34%), Positives = 32/81 (39%), Gaps = 6/81 (7%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP------PGMFPLWPPMGPFPPVPP 396
PPPP P PPP P P +P PP P +PP P PG PP+ P P
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL 1245
Query: 397 PPSSGEAVAPPSTSAAALSRP 417
P G + P L P
Sbjct: 1246 LPQVGSSTLPTPQVCGFLPPP 1266
Score = 38.5 bits (88), Expect = 0.018
Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 15/69 (21%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--FPPGMFPLWPPMG----PFPPV-- 394
PPPP G PPAP PP LP P G+ PP P PL P +G P P V
Sbjct: 1207 PPPPPLPGMGIPPAPAPP--LPPPGT---GIPPPPLLPVSGPPLLPQVGSSTLPTPQVCG 1261
Query: 395 --PPPPSSG 401
PPP SG
Sbjct: 1262 FLPPPLPSG 1270
Score = 37.4 bits (85), Expect = 0.041
Identities = 24/56 (42%), Positives = 26/56 (46%), Gaps = 10/56 (17%)
Query: 339 PAQSPPPPEPADQGPPPAPHP---PPLLPQ-------PPNFPQGLLPPFPPGMFPL 384
PA +PP P P PPP P PPLLPQ P L PP P G+F L
Sbjct: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL 1274
Score = 30.8 bits (68), Expect = 3.8
Identities = 38/169 (22%), Positives = 45/169 (26%), Gaps = 41/169 (24%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
A+ P + PP P AP P P + P PFP
Sbjct: 284 AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFP----------------- 326
Query: 396 PPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG------ 449
P +A A R GA T G A PG APE G
Sbjct: 327 -------EAGPGEEAAGAPVR--GAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQR 377
Query: 450 ---------PAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEEL 489
P P G P P F P P+ + T +L
Sbjct: 378 LGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQL 426
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 77.0 bits (188), Expect = 5e-14
Identities = 62/169 (36%), Positives = 68/169 (40%), Gaps = 24/169 (14%)
Query: 340 AQSPPPPEPAD-------QGPPPAPHPPPLLPQPPNFPQGLLPP-FPPGMFPLWPPMGPF 391
A +PPPP + G PP PPP PP P G LPP PP M P PPM P
Sbjct: 212 ADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPP--PPMPPG 269
Query: 392 PPVPPPPSSGEAVA---------PPSTSAAALSRPSGAATTTAAGTSATAASATASGPGS 442
PPS+G A P + P + A A PGS
Sbjct: 270 AAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGS 329
Query: 443 GSAPEAGPAPGFPFP-PPWMGM-PLPPPFAFP---PMPVPPAGFAGLTP 486
G P P PG P P PP MGM P PPF P P P+PP G G P
Sbjct: 330 GGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPP 378
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/139 (31%), Positives = 49/139 (35%), Gaps = 46/139 (33%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEA 403
P P G P P PPP +P P P G+ P PP P+ P GP PP G
Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHP-GPMPP------HGMR 374
Query: 404 VAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPP--WM 461
PP L P G +GP P PPP +
Sbjct: 375 GPPP------LMPPHG-----------------YTGP--------------PRPPPYGYQ 397
Query: 462 GMPLPPPFAFPPMPVPPAG 480
PLPPP P PVPP G
Sbjct: 398 RGPLPPPRPTPRPPVPPRG 416
Score = 37.4 bits (85), Expect = 0.041
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 15/73 (20%)
Query: 338 LPAQSPPPPEPADQGPPPAPH----PPPLLP--------QPP--NFPQGLLPPFPPGMFP 383
+P + PP P P PH PPPL+P +PP + +G LPP P P
Sbjct: 351 MPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRP 410
Query: 384 LWPPMGPF-PPVP 395
PP GP P+P
Sbjct: 411 PVPPRGPLRGPLP 423
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 76.3 bits (186), Expect = 8e-14
Identities = 56/151 (37%), Positives = 66/151 (43%), Gaps = 14/151 (9%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP---PGMFPLWPPMGPFPPV- 394
P PPP P Q P P PP PP+ P PP P P PP PV
Sbjct: 56 PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP----PPHPQPHQQQQPPPPPQDSSKPVV 111
Query: 395 --PPPPSSGEAVAPPSTSAAALSRP--SGAATTTAAGTSATAASATASGPGSGSAPEAGP 450
P P+ G APP++S+A + P SGA + G + T A S P G+ P P
Sbjct: 112 AQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP-PGAPPPTPP 170
Query: 451 APGFPFPPPWMGMPLPPPFAFP-PMPVPPAG 480
+ G P PP G P PPP A P P P P G
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201
Score = 60.5 bits (145), Expect = 5e-09
Identities = 56/174 (32%), Positives = 60/174 (34%), Gaps = 27/174 (15%)
Query: 341 QSPPPPEPAD-----QGPPPAPH----PPPLLPQPPNFP--QGLLPPFPPGMFPLWPPM- 388
Q PPPP+ + QGP PAP PP PP P G P PG P PP
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157
Query: 389 ---GPFPPVPPPPSSGEAVAPPSTSA-----AALSRPSGAATTTAAGTSATAASATASGP 440
P P P PPSSG PP AA+ P G G GP
Sbjct: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP-GPGPKQGPGPGGPKGGKMPGGP 216
Query: 441 GSGSAPEAGPAPGFPFPP------PWMGMPLPPPFAFPPMPVPPAGFAGLTPEE 488
G P G P PP P G PP+ PP G G EE
Sbjct: 217 KPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEE 270
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.1 bits (183), Expect = 2e-13
Identities = 77/263 (29%), Positives = 92/263 (34%), Gaps = 49/263 (18%)
Query: 345 PPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV----PPPPSS 400
P PA+ P AP PPP P G P PP P GP PP PPP S
Sbjct: 75 PAAPAEGAPGAAPEPPPAGRARPG-GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133
Query: 401 GEAVAPPSTSAAALSRPSGAATTTA--AGTSATAASATASGPGSGSAPEAGPAPGFPFPP 458
+ AP +AA + P A A AG +A AA A GPG G P GP PG
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA---GPGPGPGPGPGPGPG----- 185
Query: 459 PWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAM 518
P PAG P + L G +L N H A+
Sbjct: 186 ----------------PGKPAG-----PGAAQTLNGS---------AALLNSHHAAAPAV 215
Query: 519 LQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEM 578
+N L L P +V T A + P + P A+PP P
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP-- 273
Query: 579 ERPPAPESVGTEEMPEDGEPDAA 601
PPAP ++ G P AA
Sbjct: 274 --PPAPATLARPPGHPAGPPTAA 294
Score = 58.9 bits (141), Expect = 1e-08
Identities = 68/264 (25%), Positives = 93/264 (35%), Gaps = 41/264 (15%)
Query: 336 ASLPAQSPPPPEPADQGPP---PAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
A LP P P Q PP A P P P PP P P P P P P
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283
Query: 393 PVPP--PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGP 450
P P PP++ AV PP+ AA +GAA A A + GPG+ +A P
Sbjct: 284 PGHPAGPPTAAPAVPPPA--AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA---AP 338
Query: 451 APGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNI 510
APG P + PP A PA A
Sbjct: 339 APGVKAESPKRVVQAAPPAAQTLAASGPASTAA--------------------------- 371
Query: 511 HTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPG 570
+++ +Q L A++ PP P T + A V + S T ++ T
Sbjct: 372 -SMVIGPTMQ--GALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLT 428
Query: 571 ASPPAPEMERPPA-PESVGTEEMP 593
+ AP + +PP P ++ ++P
Sbjct: 429 PTVLAPRLPQPPQNPTNIQNFQLP 452
Score = 56.2 bits (134), Expect = 9e-08
Identities = 78/332 (23%), Positives = 102/332 (30%), Gaps = 83/332 (25%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLP----QPPNFPQGLLPPFPPGMFPLWPPMGPFP-- 392
PA PP PA P AP PPP P +PP P G PP P PP
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG-----PPTAAPAVPPPAAAQNG 306
Query: 393 ------PVPPP-----------PSSGEAVAPPSTSAAALS-------RPSGAATTTAAGT 428
P P P P G A A P+ A S P A T A+G
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGP 366
Query: 429 SATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMP------------------------ 464
++TAAS G+ P P PP G P
Sbjct: 367 ASTAASMVIGPTMQGALPSPAAVP-----PPAPGTPTGLPKGAAGAVTQSLSRTPTATTS 421
Query: 465 -----LPPPFAFPPMPVPPAGFAGL----TPEELRALEGHERQHLEARLQSLRNIHTLLD 515
L P P +P PP + P + + Q L Q+L +
Sbjct: 422 GIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAH 481
Query: 516 AAMLQINQYLTVLASLGPP-------RPATSVNSTEETATTVVAAAS--STSIPSSEATT 566
A + PP P T + + + T TT++ S T++ S
Sbjct: 482 AQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQ 541
Query: 567 PTPGASPPAPEMERPPAPESVGTEEMPEDGEP 598
+PG P + S+GT + G P
Sbjct: 542 RSPGVQPQL-VLGGAAQTASLGTATAVQTGTP 572
Score = 50.4 bits (119), Expect = 5e-06
Identities = 72/290 (24%), Positives = 87/290 (30%), Gaps = 71/290 (24%)
Query: 343 PPP--------PEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFP-LWPPMGPFPP 393
PPP P PA P P P P P P L PG P P GP P
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187
Query: 394 VPPPPSSGEAV------------APPSTS------AAALSRPSGAATTTAAGTSATAASA 435
P P + + + A P+ S AA L P AA T T +A
Sbjct: 188 KPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA 247
Query: 436 TASGPGSGSAPEA----GPAPGFPFPPPW-----------MGMPLPPPFAFPPMPVPPAG 480
P + S P A PA P PPP G P P PP G
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307
Query: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 540
AG P A G ++ A+ P P
Sbjct: 308 SAGAAPAPAPAAGG-----------------------PAGVSGQPGPGAAAAAPAPGVKA 344
Query: 541 NSTEET------ATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAP 584
S + A +AA+ S +S PT + P+P PPAP
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394
>gi|21314654 ring finger protein 139 [Homo sapiens]
Length = 664
Score = 73.2 bits (178), Expect = 7e-13
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 18/203 (8%)
Query: 141 IVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQ 200
+ + +F+L +L + H H L F E + + + LT+ Y L +D
Sbjct: 395 VSACLFILPVLLSYVLWH--HYALNTWLFAVTAFCVELCLKVIVSLTV---YTLFMIDGY 449
Query: 201 SENPWDNKAVYMLYTELFTGFIKVLLYMAFM------TIMI----KVHTFPLFAIRPMYL 250
W+ Y+ Y TG I ++ M T+M K+ F + + +
Sbjct: 450 YNVLWEKLDDYVYYVRS-TGSIIEFIFGVVMFGNGAYTMMFESGSKIRAF-MMCLHAYFN 507
Query: 251 AMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHI 310
Q K + R A++ +N+L P+ LQ +++VC IC E T A+ PCNH
Sbjct: 508 IYLQAKNGWKTFMNRRTAVKKINSL-PEIKGSRLQEINDVCAICYHEFTTSARITPCNHY 566
Query: 311 FHTSCLRSWFQRQQTCPTCRMDV 333
FH CLR W Q TCP C V
Sbjct: 567 FHALCLRKWLYIQDTCPMCHQKV 589
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/134 (32%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 331 MDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGP 390
++ ++ L Q+PPPP P+ GPPP P PP PP +G P PP P P
Sbjct: 265 VEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPP------PSRAP 318
Query: 391 FPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGP 450
PPPP S +VA P + P A ++A + + G G + P P
Sbjct: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
Query: 451 APGFPFPPPWMGMP 464
P P PPP G+P
Sbjct: 379 PPPPPGPPPPPGLP 392
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/128 (32%), Positives = 45/128 (35%), Gaps = 31/128 (24%)
Query: 343 PPPPEPADQGPPP-------APHPPPLL-------PQPPNFPQGLLPPFPPG-MFPLWPP 387
PPPP P + GPPP AP PPP P PP+ P +PP PP M+P PP
Sbjct: 289 PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPP 348
Query: 388 M-------GPFPPVP---------PPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSAT 431
GP PP P PPP P L T AG A
Sbjct: 349 ALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAA 408
Query: 432 AASATASG 439
G
Sbjct: 409 LLDQIREG 416
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/115 (31%), Positives = 41/115 (35%), Gaps = 16/115 (13%)
Query: 375 PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAAS 434
PP PP P G PP PPPP + PP+ A P A T A +
Sbjct: 277 PPPPP------PSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330
Query: 435 ATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF---------PPMPVPPAG 480
+ A P + P P P P G P PPP PP P PP G
Sbjct: 331 SVAVPPPPPNRMYPPPPPALPSSAP-SGPPPPPPSVLGVGPVAPPPPPPPPPPPG 384
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 72.0 bits (175), Expect = 2e-12
Identities = 50/154 (32%), Positives = 58/154 (37%), Gaps = 17/154 (11%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 69 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAAT------TTAAGTSATAASATASGPGSGSAP 446
P PPP G+ PP ++P G G + + +S + G G P
Sbjct: 129 PQGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185
Query: 447 EAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
+ G P P PPP PP P PP G
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Score = 72.0 bits (175), Expect = 2e-12
Identities = 51/155 (32%), Positives = 58/155 (37%), Gaps = 18/155 (11%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP---------FPPGMFPLWPPMGPF 391
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 392 PPVPPPPSSGEAVAPPSTSAAALSRPSGAAT------TTAAGTSATAASATASGPGSGSA 445
P PPP G+ PP ++P G G S + +S + G G
Sbjct: 252 QPQGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP 308
Query: 446 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
P+ G P P PPP PP P PP G
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/157 (31%), Positives = 58/157 (36%), Gaps = 22/157 (14%)
Query: 341 QSPPPPEPADQGPPP-------APHPPPLLPQPPNFPQG----LLPPFPPGMFPLWPPMG 389
Q PPPP QGPPP P PP PP PQG PPG PP G
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--PQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 390 PFPPVPPPPSSGEAVAPPSTSAAALSRPSGAAT------TTAAGTSATAASATASGPGSG 443
P PPP G+ PP ++P G G + + ++ + G G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG 244
Query: 444 SAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
P+ G P P PPP PP P PP G
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Score = 57.0 bits (136), Expect = 5e-08
Identities = 54/145 (37%), Positives = 57/145 (39%), Gaps = 21/145 (14%)
Query: 341 QSPPPPEPADQGPPP-------APHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPPM 388
Q PPPP QGPPP + PP PQ P N PQG PP PPG PP
Sbjct: 275 QGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQ 331
Query: 389 GPFPPVPPPPSSGEAVAPP---STSAAALSRP-SGAATTTAAGTSATAASATASG-PGSG 443
G P PPP PP S S +A S P G + A G P
Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391
Query: 444 SAPEAGPAPGFPFPPPWMGMPLPPP 468
AP AG G P PP G P PP
Sbjct: 392 QAPPAGQPQGPPRPPQG-GRPSRPP 415
Score = 56.6 bits (135), Expect = 7e-08
Identities = 49/148 (33%), Positives = 55/148 (37%), Gaps = 22/148 (14%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPP-LLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
L A P +PP QGPP P P PQ N PQG PP PPG PP G
Sbjct: 31 LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNK 88
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P PPP G+ PP P G + + + G G P+ G P
Sbjct: 89 PQGPPP-PGKPQGPP---------PQG---------DKSRSPRSPPGKPQGPPPQGGNQP 129
Query: 453 GFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
P PPP PP P PP G
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPG 157
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/181 (32%), Positives = 67/181 (37%), Gaps = 41/181 (22%)
Query: 337 SLPAQSPP--PPEPADQG--PPPAPHPPPLLPQPP-----NFPQGLLPP----------- 376
S A+SPP P P QG P P PPP PQ P N PQG PP
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 377 -------FPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAAT------T 423
PPG PP G P PPP G+ PP ++P G
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGP 348
Query: 424 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPP--PFAFPPM--PVPPA 479
G S + ++ + G G + G P P PPP G P P P A P P PP
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP-PPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Query: 480 G 480
G
Sbjct: 408 G 408
Score = 47.4 bits (111), Expect = 4e-05
Identities = 39/132 (29%), Positives = 45/132 (34%), Gaps = 34/132 (25%)
Query: 356 APHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALS 415
A +P PQ N PQG PP PPG PP G P PPP G+ PP
Sbjct: 33 AGNPQGAPPQGGNKPQG--PPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-------- 82
Query: 416 RPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 475
P G+ P+ P PG P PP G P + P P
Sbjct: 83 ------------------------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 118
Query: 476 VPPAGFAGLTPE 487
P G P+
Sbjct: 119 QGPPPQGGNQPQ 130
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 72.0 bits (175), Expect = 2e-12
Identities = 49/150 (32%), Positives = 54/150 (36%), Gaps = 10/150 (6%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPG--SGSAPEAGP 450
P PPP G+ PP P + ++ S PG G P+ G
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
Query: 451 APGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
P P PPP PP P PP G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258
Score = 71.2 bits (173), Expect = 3e-12
Identities = 49/150 (32%), Positives = 53/150 (35%), Gaps = 10/150 (6%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPG--SGSAPEAGP 450
P PPP G+ PP P + + S PG G P+ G
Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 167
Query: 451 APGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
P P PPP PP P PP G
Sbjct: 168 QPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197
Score = 65.9 bits (159), Expect = 1e-10
Identities = 54/158 (34%), Positives = 62/158 (39%), Gaps = 22/158 (13%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--------FPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAAT------TTAAGTSATAASATASGPGSGSAP 446
P PPP G+ PP ++P G A G S + ++ + G G
Sbjct: 230 PQGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
Query: 447 EAGPAPGFPFPPPWMGMPLPP--PFAFPPM--PVPPAG 480
+ G P P PPP G P P P A P P PP G
Sbjct: 287 QEGNNPQGP-PPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/162 (30%), Positives = 56/162 (34%), Gaps = 30/162 (18%)
Query: 340 AQSPPPPEPADQGPPPA----PHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
++SP P QGPPP P PP PP PQG PP G P PP P P
Sbjct: 148 SRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQG--PPPQGGKKPQGPPPPGKPQGP 202
Query: 396 PP--PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPG 453
PP S + +PP P G P G+ P+ P PG
Sbjct: 203 PPQGDKSRSSQSPPGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258
Query: 454 FPFPPPWM------------GMPLPPPFA---FPPMPVPPAG 480
P PP G P PP P P PPAG
Sbjct: 259 KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300
Score = 46.6 bits (109), Expect = 7e-05
Identities = 51/142 (35%), Positives = 55/142 (38%), Gaps = 30/142 (21%)
Query: 337 SLPAQSPP--PPEPADQG--PPPAPHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPP 387
S +QSPP P P QG P P PPP PQ P N PQG P PPG P
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG---PPPPG-----KP 260
Query: 388 MGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASG-PGSGSAP 446
G PP S A +PP +P G G + A G P AP
Sbjct: 261 QG--PPAQGGSKSQSARSPP-------GKPQG--PPQQEGNNPQGPPPPAGGNPQQPQAP 309
Query: 447 EAGPAPGFPFPPPWMGMPLPPP 468
AG G P PP G P PP
Sbjct: 310 PAGQPQGPPRPPQG-GRPSRPP 330
Score = 31.2 bits (69), Expect = 2.9
Identities = 27/106 (25%), Positives = 32/106 (30%), Gaps = 37/106 (34%)
Query: 387 PMGPFP-----PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPG 441
P GP P P PPP G+ PP P
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPP--------------------------------PQ 63
Query: 442 SGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPE 487
G+ P+ P PG P PP G P + P P P G P+
Sbjct: 64 GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 109
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 71.6 bits (174), Expect = 2e-12
Identities = 59/166 (35%), Positives = 69/166 (41%), Gaps = 24/166 (14%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLL-----PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
+ PP P GPP PPP L P+PP P+ L PP PPG PL PPM P P P
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPP-LPESLPPP-PPGGLPL-PPMPPTGPAP 271
Query: 396 PPPSSGEAVAPPSTS----AAALSRPSGAATTTAAGTSATAASATASGPG-----SGSAP 446
P + PP+ A + P+ A G A PG SG P
Sbjct: 272 SGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHP 331
Query: 447 EA----GPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPE 487
A PAPG PP G+ P P PP P V P AG+ P+
Sbjct: 332 PAPGVHPPAPG--VHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQ 375
Score = 57.4 bits (137), Expect = 4e-08
Identities = 53/152 (34%), Positives = 62/152 (40%), Gaps = 13/152 (8%)
Query: 339 PAQSPPPPEPADQGPPPAP--HPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPP 396
PA S PP P Q PPPAP HPP + PP G+ PP PG+ P P + P P
Sbjct: 269 PAPSGPPGPP--QLPPPAPGVHPPAPVVHPP--ASGVHPP-APGVHPPAPGVHPPAPGVH 323
Query: 397 PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPF 456
PP+SG V PP A + P+ A G A PG P AG P P
Sbjct: 324 PPTSG--VHPP---APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPG 378
Query: 457 PPPWMGMPLP-PPFAFPPMPVPPAGFAGLTPE 487
P P P PP P G+ P+
Sbjct: 379 VHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ 410
Score = 40.0 bits (92), Expect = 0.006
Identities = 28/74 (37%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 339 PAQSPPPPEPADQGP-----PPAPHP--PPLLPQPPNFPQ---GLLPP--FPPGMFPLWP 386
P PP P Q P PP HP P + PQPP G+ PP PP + P P
Sbjct: 391 PGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLP 450
Query: 387 PMGPFPPVPPPPSS 400
GP PPPP++
Sbjct: 451 SEGPGNIPPPPPTN 464
Score = 39.7 bits (91), Expect = 0.008
Identities = 39/134 (29%), Positives = 46/134 (34%), Gaps = 9/134 (6%)
Query: 339 PAQSPPPP---EPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
P PP P PA PPAP P P P + P PG+ P P + P P
Sbjct: 334 PGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGV 393
Query: 396 PPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFP 455
PP+ G P +P G +A G S PG P P
Sbjct: 394 HPPAPGMHPQAPGVH----PQPPG-VHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPP 448
Query: 456 FPPPWMG-MPLPPP 468
P G +P PPP
Sbjct: 449 LPSEGPGNIPPPPP 462
Score = 39.3 bits (90), Expect = 0.011
Identities = 43/140 (30%), Positives = 49/140 (35%), Gaps = 24/140 (17%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
PA PP P PPAP P P G+ PP G+ P P + P P P
Sbjct: 332 PAPGVHPPAPGVH--PPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQ 389
Query: 399 SSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPG-SGSAPEAGPAPGFPFP 457
+ G V PP A G A PG SAP P P P
Sbjct: 390 APG--VHPP-----------------APGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHP 430
Query: 458 P-PWMGMPLP-PPFAFPPMP 475
P + P P PP PP+P
Sbjct: 431 SNPGVHPPTPMPPMLRPPLP 450
Score = 35.4 bits (80), Expect = 0.16
Identities = 41/163 (25%), Positives = 47/163 (28%), Gaps = 64/163 (39%)
Query: 440 PGSGSAPEAGPAPGFPFPPPWM------------GMPLPPPFAFPPMPVPPAGFAGLTPE 487
P S P AGP PG PPP + +P PPP P P+PP G A P
Sbjct: 218 PAPPSLP-AGP-PGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPP 275
Query: 488 ELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETA 547
GPP+ A
Sbjct: 276 --------------------------------------------GPPQLPPPAPGVHPPA 291
Query: 548 TTVVAAASSTSIPSSEATTPTPGASPPAPEME------RPPAP 584
V AS P+ P PG PPAP + PPAP
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAP 334
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/158 (34%), Positives = 68/158 (43%), Gaps = 17/158 (10%)
Query: 343 PPPPEPADQGPPPAP-HPPPLLPQPPNFPQGLLPPF------PPGM-FPLWPPMGP--FP 392
PPP P Q PPP P PPP+L PP+ P ++PP PPGM P+ PP P P
Sbjct: 517 PPPFVPYSQMPPPLPTMPPPVL--PPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP 574
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P PPS A PP +LS S+TA P SA P P
Sbjct: 575 PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT---PPP 631
Query: 453 GFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELR 490
G PPP + +PP P+P + + PE+ R
Sbjct: 632 G--IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
Score = 65.1 bits (157), Expect = 2e-10
Identities = 89/359 (24%), Positives = 133/359 (37%), Gaps = 76/359 (21%)
Query: 309 HIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPA---------PHP 359
H+ L+ Q+Q C VL+ P PPPP P PPP P
Sbjct: 57 HLAQLQQLQQMHQKQMQC------VLQ---PHHLPPPPLP----PPPVMPGGGYGDWQPP 103
Query: 360 PPLLPQPP---------------------NFPQGLL----------PPFPPGMFPLWPPM 388
PP +P PP + P GL+ PP PPG + PP
Sbjct: 104 PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSY--MPPS 161
Query: 389 GPF--PPVPP----PPSSGEAVAPPSTSAAALSRPSGA-ATTTAAGTSATAASATASGPG 441
+ PP PP PP+S + PP+ + + S PS + T + +S++++S +
Sbjct: 162 QSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221
Query: 442 SGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLE 501
P + +P P L P PP PP + E L + G + + E
Sbjct: 222 QSYLPSSQASPSRPSQGHSKSQLLAP----PPPSAPPGNKTTVQQEPLES--GAKNKSTE 275
Query: 502 ARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPS 561
+ + + + Q Y L SL + T V+ VVA + +
Sbjct: 276 QQQAAPEPDPSTMTPQEQQQYWYRQHLLSL---QQRTKVHLPGHKKGPVVAKDTPEPV-K 331
Query: 562 SEATTPTPGASPPAPEMERPPAP---ESVGTEEMPEDGEPDAAELRRRRLQKLESPVAH 617
E T P P +P E PP P E V PE+ + + E RL++L++ AH
Sbjct: 332 EEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPE-EDARLKQLQAAAAH 389
Score = 57.0 bits (136), Expect = 5e-08
Identities = 50/149 (33%), Positives = 61/149 (40%), Gaps = 20/149 (13%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
+S P PPP + + PPP PP + +P P P P+ PP P PP+P
Sbjct: 1500 SSRPGMYPPPG--SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPI-PPPPPPPPLP 1556
Query: 396 PPPSSGEAVAPPSTSAAALSRPSGAA------TTTAAGTSATAASATASGPGSGSAPEAG 449
PPP V P TSA R + T G ++ S TA+ P SAP
Sbjct: 1557 PPP----PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIP---SAPVLP 1609
Query: 450 PAPGFPFPPPWMGMPLPPPFAFPPMPVPP 478
P P PP P P P PPM PP
Sbjct: 1610 PPPVHSSIPP----PGPVPMGMPPMSKPP 1634
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/176 (27%), Positives = 65/176 (36%), Gaps = 24/176 (13%)
Query: 334 LRASLPAQSPPPPEPADQGPPP--------APHPPPLLPQPP----NFPQGLLPP-FPPG 380
L ++ P PPP + GPPP + PPP++P PP P G+ PP P G
Sbjct: 582 LSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQG 641
Query: 381 MFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGP 440
+ PP PVPP SS + P A L P + SA S
Sbjct: 642 I----PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQ 697
Query: 441 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP-----PAGFAGLTPEELRA 491
+ AP + A P+ L A P P+ P GL P+ R+
Sbjct: 698 VNSKAPLSKSA--LPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/159 (28%), Positives = 54/159 (33%), Gaps = 24/159 (15%)
Query: 327 PTCRMDVLRASLPAQSPPPPE-----PADQGPPPAP------HPPPLLPQPPNFPQGLLP 375
P L A++P PPP P PP P PPP+LP P G P
Sbjct: 544 PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPP 603
Query: 376 PFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASA 435
PP P PPV P P A PP + P G A A+S+
Sbjct: 604 VLPPPSLSSTAP----PPVMPLPPLSSATPPPGIPPPGV--PQGIPPQLTAAPVPPASSS 657
Query: 436 TASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPM 474
+S PE P P P P PP PP+
Sbjct: 658 QSS-----QVPEK-PRPAL-LPTPVSFGSAPPTTYHPPL 689
Score = 43.9 bits (102), Expect = 4e-04
Identities = 41/138 (29%), Positives = 50/138 (36%), Gaps = 27/138 (19%)
Query: 380 GMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAAALSRPSGAATTTAAG--TSATAASAT 436
G + PP P+ +PPP P+ V PPS + P+ AT G S
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP-PALPATVPPPGMPPPVMPPSLP 570
Query: 437 ASGPGSGSAP---EAGPAPGFP------------FPPPWMGMPLPPPF--------AFPP 473
S P G P AGP P P PPP + PPP A PP
Sbjct: 571 TSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPP 630
Query: 474 MPVPPAGFAGLTPEELRA 491
+PP G P +L A
Sbjct: 631 PGIPPPGVPQGIPPQLTA 648
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 24/92 (26%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLL-PQ------------------PPNFPQGLLP 375
R+S+P PP P P PPP P PPP++ PQ N QGL
Sbjct: 1534 RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNS 1593
Query: 376 PFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPP 407
F + P PV PPP ++ PP
Sbjct: 1594 EFKSETAAI-----PSAPVLPPPPVHSSIPPP 1620
Score = 35.0 bits (79), Expect = 0.20
Identities = 39/123 (31%), Positives = 47/123 (38%), Gaps = 37/123 (30%)
Query: 381 MFPLWPPMG-----PFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASA 435
M+P W G P PPVPPPP VA P S P +++TT A S++ +
Sbjct: 1 MYPNWGRYGGSSHYPPPPVPPPP----PVALPEASPG----PGYSSSTTPAAPSSSGFMS 52
Query: 436 TASGPGSG---------------SAPEAGPAPGFPFPPPWM-----GMPLPPPFAFPPMP 475
+ P P P P PPP M G PPP PPMP
Sbjct: 53 FREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLP-PPPVMPGGGYGDWQPPP---PPMP 108
Query: 476 VPP 478
PP
Sbjct: 109 PPP 111
Score = 31.6 bits (70), Expect = 2.3
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 13/50 (26%)
Query: 442 SGSAPEAGPAPGFPFPPPWMGMP--------LPP-----PFAFPPMPVPP 478
+ S P P PG PPP MG P PP P PP+P+PP
Sbjct: 1499 TSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
Score = 30.0 bits (66), Expect = 6.6
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 5/67 (7%)
Query: 456 FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP--EELRALEGHERQHLEARLQSLRNIHTL 513
+PPP +P PPP A P P + TP QHL A+LQ L+ +H
Sbjct: 14 YPPP--PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHL-AQLQQLQQMHQK 70
Query: 514 LDAAMLQ 520
+LQ
Sbjct: 71 QMQCVLQ 77
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/327 (26%), Positives = 111/327 (33%), Gaps = 73/327 (22%)
Query: 334 LRASLPAQSPPPPEPADQGP------------------------PPAPHPPPLLPQPPNF 369
L ++ P PP P P+ GP P PH P+ P P +
Sbjct: 763 LGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALY 822
Query: 370 PQ-------GLLPPFPPGMFPLWPP---MGPFPPVPPPPSSGEAVAPPSTSAAALSRPSG 419
P GL+P P + P +GP PPV PS+ PP S L+
Sbjct: 823 PAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSA----PPPQFSGPELAMAVR 878
Query: 420 AATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFP---PMPV 476
ATTT A S TA P AP P P FP PPP PLP P+ +P P+
Sbjct: 879 PATTTVDSIQAPIPSHTAPRPNPTPAP---PPPCFPVPPP---QPLPTPYTYPAGAKQPI 932
Query: 477 P---------PAGFAG--LTPEELRALEGHERQHL--EARLQSLRNIHTLLDAAMLQINQ 523
P PAGF + P+ + H Q + Q L H L Q
Sbjct: 933 PAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPP-----Q 987
Query: 524 YLTVLASLGP----PRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEME 579
+L P P+P T + + +P+ P P PP P
Sbjct: 988 APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQP--- 1044
Query: 580 RPPAPESVGTEEMPEDGEPDAAELRRR 606
P P + G P AA L R
Sbjct: 1045 -PHPPLAYGPAPSTRPMGPQAAPLTIR 1070
Score = 60.1 bits (144), Expect = 6e-09
Identities = 51/176 (28%), Positives = 63/176 (35%), Gaps = 29/176 (16%)
Query: 328 TCRMDVLRASLPAQSPPPPEPADQGPPPA-PHPPPL-LPQPPNFPQGLLPPFP------- 378
T +D ++A +P+ + P P P PPP P PPP LP P +P G P P
Sbjct: 881 TTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSS 940
Query: 379 --PGMFPLWPPMGPFPPVPPPPSSGEAVAP-PSTSAAALSRP-------SGAATTTAAGT 428
P FP P +GP P P P +A P P L P G +
Sbjct: 941 GIPAGFPA-PRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYP 999
Query: 429 SATAASA---------TASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 475
A T PG P + PFP P P PP A+ P P
Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAP 1055
Score = 59.7 bits (143), Expect = 8e-09
Identities = 56/173 (32%), Positives = 63/173 (36%), Gaps = 19/173 (10%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLL-PQPPNFPQGLLPP--FPPGMFPLWPPMGPFP 392
+ +PA P P P P PHP PQPP P L P FPP L PP P+P
Sbjct: 940 SGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYP 999
Query: 393 PVPPPPSSGEAVAP------PSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAP 446
P P G+ P P + L SGA + G A GP + P
Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRP 1059
Query: 447 EAGP--APGFPFPPPWMGMPLPPPFAFP-------PMPVPPAGFAGLTPEELR 490
GP AP P G P P P P PVPP A P LR
Sbjct: 1060 -MGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLR 1111
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/176 (28%), Positives = 62/176 (35%), Gaps = 37/176 (21%)
Query: 337 SLPAQSPPPPEPADQGPP----PAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
+LP SP PP+P PP PAP P+ PQ P + P G P + P
Sbjct: 1033 ALPFPSPGPPQPPH--PPLAYGPAPSTRPMGPQAA--PLTIRGPSSAGQSTPSPHLVP-- 1086
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P PS G PP RP A A AA +S P S P
Sbjct: 1087 --SPAPSPGPGPVPP--------RPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGG 1136
Query: 453 GFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 508
G P P V A G P+ LR +E +H E RL+ L+
Sbjct: 1137 GQPL--------------LQPTKVDAA--EGRRPQALRLIERDPYEHPE-RLRQLQ 1175
Score = 38.5 bits (88), Expect = 0.018
Identities = 73/286 (25%), Positives = 92/286 (32%), Gaps = 91/286 (31%)
Query: 323 QQTCPT---CRMDVLRASLPAQSPPPP-------------EPADQGPPPAPH---PPPLL 363
Q TC R +L L + PP P E + G PP PP ++
Sbjct: 694 QSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMV 753
Query: 364 --PQPPNFPQGLLPP--FPPGMFPLWPPMGPF---PPVPPPPSSGEAVAPPSTSAAALSR 416
P+ P+ G P FPP FP GP P+PP SG T
Sbjct: 754 AGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGP------TQLIQPRA 807
Query: 417 PSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPV 476
P A A G + A A P G P + P G P++G+ PP A P
Sbjct: 808 PGPHAMPVAPGPALYPAPAYT--PELGLVPRSSPQHGV-VSSPYVGVGPAPPVAGLPS-A 863
Query: 477 PPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRP 536
PP F+G PE A+ RP
Sbjct: 864 PPPQFSG--PELAMAV------------------------------------------RP 879
Query: 537 ATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 582
AT+ T ++ A IPS A P P +PP P PP
Sbjct: 880 ATT------TVDSIQAP-----IPSHTAPRPNPTPAPPPPCFPVPP 914
Score = 38.1 bits (87), Expect = 0.024
Identities = 31/80 (38%), Positives = 35/80 (43%), Gaps = 16/80 (20%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
ASLP + PP G PPA P P P + P L P P P PPVP
Sbjct: 1518 ASLPGPAEPP------GLPPASLPEST-PIPSSSPPPLSSPLPEA-----PQPKEEPPVP 1565
Query: 396 PPPSSGEAVAPPSTSAAALS 415
PSSG PPS+S L+
Sbjct: 1566 EAPSSG----PPSSSLELLA 1581
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 68.9 bits (167), Expect = 1e-11
Identities = 73/271 (26%), Positives = 97/271 (35%), Gaps = 44/271 (16%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PPP P PP PP PP P P P + PF P P PP
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672
Query: 399 SSGEAVAPPSTSAA-ALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
P S + + + PS A + AA S AS P S SA P
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT----------P 722
Query: 458 PPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAA 517
PP PPP A PP+ VPP+ A + + LL A
Sbjct: 723 PP----QAPPPLAAPPLQVPPSPPAS--------------PPMSPSATPPPRVPPLLAAP 764
Query: 518 MLQI------NQYLTVLASLGPPRPATSVNSTEETATTVVAA-------ASSTSIPSSEA 564
LQ+ + ++ LA P P + + A+ + S S+P S
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 565 TTPTPGASP--PAPEMERPPAPESVGTEEMP 593
TP P A P AP ++ PP+P + T + P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Score = 68.9 bits (167), Expect = 1e-11
Identities = 74/255 (29%), Positives = 96/255 (37%), Gaps = 34/255 (13%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
A+ P Q PP P PA P+ PPP P P P +PP PP P+ P P P VP
Sbjct: 700 AAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 396 P----PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATA-ASATASGPGSGSAPEAGP 450
P PP P S + L++P A A A S AS PG +
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 451 APGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 508
P P PPP PP A P + VPP+ A T LQ+ R
Sbjct: 819 LPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQAPR 856
Query: 509 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS----EA 564
T + + LA PP P+ S +ST ++S+TS P ++
Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 565 TTPTPGASPPAPEME 579
A+ P P+ E
Sbjct: 917 GPEGGAAASPPPDAE 931
Score = 63.2 bits (152), Expect = 7e-10
Identities = 83/290 (28%), Positives = 105/290 (36%), Gaps = 51/290 (17%)
Query: 338 LPAQSPPPPEPADQGP--PPAPHPPP---LLPQPPNFPQGLLPPF---PPGMFPLWPPMG 389
LPA PP P A P PP+P PP LP PP P PP PP P P +
Sbjct: 327 LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSLQ 384
Query: 390 PFPPVPPPPS--SGEAVAPPSTSA-------AALSRPSGAATTTAAGTSATAASATASGP 440
PP+ P S S APPS A +L P+ AT + S A+ + P
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 441 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHL 500
S P + P P P + +P PP P + LT L+AL
Sbjct: 445 ---SRPASTPPDSPPLQAP-LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 501 EARLQSL-----RNIHTLLDAAMLQINQYLTV-----LASLGPP--RPATSVNSTEETAT 548
+A L SL +L ++ LT L SL PP + A++ +T T
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
Query: 549 TVVAAASSTSIPSSEATTPTPG----------------ASPPAPEMERPP 582
A P S TTP P ASPP + PP
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Score = 61.6 bits (148), Expect = 2e-09
Identities = 70/260 (26%), Positives = 88/260 (33%), Gaps = 46/260 (17%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPP--NFPQGLLPPFPPGMFPLWPPMGPFPPVPPP--- 397
PP + PP PP L PP N P PP PL P PP P P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 398 --PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFP 455
P S PP T PS AT A A+ P +P A P P
Sbjct: 570 QAPPSPLTTPPPET-------PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ-- 620
Query: 456 FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLD 515
PP + +P PP P + A +P+ AL H Q
Sbjct: 621 -APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ----------------- 662
Query: 516 AAMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEATTP--TPGAS 572
A V A PP P S ++T + AA +P S +P +P A+
Sbjct: 663 -APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 573 PP--------APEMERPPAP 584
PP AP ++ PP+P
Sbjct: 722 PPPQAPPPLAAPPLQVPPSP 741
Score = 58.5 bits (140), Expect = 2e-08
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 27/164 (16%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP PPM
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPM 716
Query: 389 GPFPPVPPPPSSGEAVAPP---STSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA 445
P PPP + APP S A S +AT AA P S
Sbjct: 717 SP-SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP---SP 772
Query: 446 PEAGPAPGFPFPPPWMGMPLPPPFAFPP---MPVPPAGFAGLTP 486
P + P PPP PP A PP +P PPA F G P
Sbjct: 773 PASLPMSPLAKPPP----QAPPALATPPLQALPSPPASFPGQAP 812
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/298 (26%), Positives = 112/298 (37%), Gaps = 60/298 (20%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
++ P SP P+ +G P AP P P P G+ L PP P
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPS-------------QPKPKGLQALRPPQ----VTP 287
Query: 396 PPPSSGEAVAPPSTSAAALSRPSG--AATTTAAGTSATAASAT--ASGPGSGSAPEAGPA 451
P + A+ P S+S A PSG A +AT AT S P + P A P+
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 452 PGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIH 511
P PP +P PP A PP PP+ +T ++A LQ++ I
Sbjct: 348 PS--APPSLQTLPSPP--ATPPSQAPPS----MTTPPMQA---------PPSLQTIPPI- 389
Query: 512 TLLDAAMLQINQYLTVLASLGPPRP--------ATSVNSTEETATTVVAAASSTSIPSSE 563
Q+ LT + PP P TS+ S AT S +S
Sbjct: 390 --------QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 564 ATTPTPGASPP-APEMERP---PAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVAH 617
+ P ++PP +P ++ P PA + T P P ++ L LQ L S +H
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQALSSLASH 498
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/203 (28%), Positives = 71/203 (34%), Gaps = 49/203 (24%)
Query: 327 PTCRMDVLRASLPAQSPPPP----------EPADQGPPPAPHPP-PLLPQPPNFPQGLLP 375
P R+ L A+ P Q PP P +P Q PP PP LP PP G P
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 376 PFPPGMFPLWP--------------PMGPFPPVPP----------PPSSGE--------- 402
P P+ P P+ PP PP PP+ G
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 403 --AVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 460
A+AP + S S + AG S++A S G S PE G A PPP
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS---PPPD 929
Query: 461 MGMPLPPPFAFPPMPVPPAGFAG 483
+ P A+ P PP F G
Sbjct: 930 AELAACHPAAWSRGPAPPLAFRG 952
Score = 53.1 bits (126), Expect = 7e-07
Identities = 86/340 (25%), Positives = 115/340 (33%), Gaps = 66/340 (19%)
Query: 334 LRASLPAQSPPPPE-------PADQGPPPAPHPPPL----LPQPPNFPQGL---LPPFPP 379
L+A P Q PP + P P P P +P P N L LPP PP
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336
Query: 380 --GMFPLWPPMGPFPP----VPPPPSSGEAVAPPSTSAAALSRP---------------- 417
PL PP PP +P PP++ + APPS + + P
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 418 -------------SGAATTTAAGTSATAAS---------ATASGPGSGSAPEAGPAPGFP 455
S TT+ G+ A+ T + S S P + P P
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456
Query: 456 FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLD 515
P + +P PP P + LT L+AL +A L SL + L
Sbjct: 457 LQAP-LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL-IMPPLET 514
Query: 516 AAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPA 575
+ L T ASL P + T A ++ + + P P +PP+
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574
Query: 576 PEMERPP-APESVGTEEMPEDGEPDAAELRRRRLQKLESP 614
P PP P S+ T P P A L LQ L SP
Sbjct: 575 PLTTPPPETPSSIAT---PPPQAPPA--LASPPLQGLPSP 609
Score = 47.8 bits (112), Expect = 3e-05
Identities = 74/273 (27%), Positives = 98/273 (35%), Gaps = 46/273 (16%)
Query: 359 PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPST---SAAALS 415
P P P P + G+ P P PP P S + + ST S AA
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 416 RPSGAA-----TTTAAGTSATAASATA-SGPGSGSAPEAGPAPGFPFPPPWMGM-PLPPP 468
RPS + + +SAT S+ A SGP + P AP P P G+ L PP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPP 283
Query: 469 FAFPPM--PVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLT 526
PP P G +P + G + + + N T L A +
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP----DNAATPLPATL-------- 331
Query: 527 VLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPA---PEMERPPA 583
PP P AT + A S S P S T P+P A+PP+ P M PP
Sbjct: 332 ------PPSP--------PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
Query: 584 PESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 616
+ +P P + L LQ SP+A
Sbjct: 378 QAPPSLQTIPPIQVPHS--LTSPSLQAPPSPLA 408
Score = 38.9 bits (89), Expect = 0.014
Identities = 85/368 (23%), Positives = 115/368 (31%), Gaps = 99/368 (26%)
Query: 330 RMDVLRASLPAQSPPPPEPA--DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPL--- 384
+ D +A A++P P PP +P PPP P P + L G PL
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAER 61
Query: 385 ------------WPPMGPF--------PPVPPPPSSGEAV-APP--STSAAALSRPSGAA 421
P GP P PP+SG APP +TS +S P A+
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 422 TTTAAGT-----------------SATAASATASGPGSGSAPEAGPAPGFPFPP------ 458
TT G AT A ++ +GP PG P P
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 459 ---PWMGMPLPPPFAFPPMPVP------------------------PAGFAGLTPEELRA 491
+G+P P P A P P P+ GL R+
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 492 LEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR---------PATSVNS 542
L L + +S + A L +L PP+ PA S
Sbjct: 242 LSS-SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 543 TEETATTVVAAASSTSIPSSE-ATTPTPGASPPAPEM--------ERPPAPESVGTEEMP 593
+ AT + + +P + A TP P PP+P + P AP S+ T P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 594 EDGEPDAA 601
P A
Sbjct: 361 PATPPSQA 368
Score = 38.5 bits (88), Expect = 0.018
Identities = 59/233 (25%), Positives = 77/233 (33%), Gaps = 33/233 (14%)
Query: 379 PGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATAS 438
PG+ PP P PP P P++ + +A A+ R A G + SA +
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLG----AAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 439 GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT--PEELRALEGHE 496
GP + SA + P P G PP P PV G A T P L G +
Sbjct: 78 GP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL----GQK 132
Query: 497 RQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASS 556
+ A R A+ P R A S + +T+ S
Sbjct: 133 GLRISAEETVARG------------------KATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 557 TSIPSSEATTPTPGASPPAPEME-RPPAP---ESVGTEEMPEDGEPDAAELRR 605
S A G PAP RPP +SV + EP A RR
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Score = 30.8 bits (68), Expect = 3.8
Identities = 35/122 (28%), Positives = 43/122 (35%), Gaps = 13/122 (10%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP-GMFPLWPPMGPFPPVPPPPSSGE 402
P P A +G P AP P P P + GL + G P G P P P +SG
Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 1002
Query: 403 AVAPPSTSAAALSRPSGA-----------ATTTAAGTSATAASATASGPGSGSAPEAGPA 451
A + + A+ P A A+ S T A A G GS G A
Sbjct: 1003 KAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 1062
Query: 452 PG 453
G
Sbjct: 1063 EG 1064
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 68.9 bits (167), Expect = 1e-11
Identities = 83/312 (26%), Positives = 104/312 (33%), Gaps = 66/312 (21%)
Query: 340 AQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG-LLPPFPPGMFPLWPPMGPFPPVPPPP 398
A+ PPPP PPAP PPP LP P P L PP PP P+ PP P PP PPP
Sbjct: 399 AKLPPPPLT-----PPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSPPPLPSPP-PPPA 449
Query: 399 SSGEAVAPPSTSAAALSRPSGAATTTA----------AGTSATAASATASGPGSGSAPEA 448
+ +PP A SR G T AG T+ +G PE
Sbjct: 450 QEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED 509
Query: 449 GPAPG-------------------------FPFPPPWMGM--PLPPPFAFPPMPVPPAGF 481
P P +M P PP P+ PP
Sbjct: 510 SPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT 569
Query: 482 AGLTPEELRALEGHERQHLEARL-----QSLRNIHTLLDAAMLQINQYLTVLASLGPPRP 536
+ P+E + R + R+I + + L PP P
Sbjct: 570 SPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP 629
Query: 537 ATSVNSTEETATTVVAAASSTSIPSSEA--------TTPTPGASPPAPEMERPPAPESVG 588
A S T++ + SEA TP P +P APE E PPA +S
Sbjct: 630 APSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS-- 687
Query: 589 TEEMPEDGEPDA 600
P + EP A
Sbjct: 688 ----PAEPEPRA 695
Score = 57.0 bits (136), Expect = 5e-08
Identities = 76/282 (26%), Positives = 102/282 (36%), Gaps = 59/282 (20%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP---PLLPQPPNF--PQGLLPPFPPGM 381
PT R L LP P PP P PPPAP PLL + P F + L + +
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
Query: 382 FPLWPPMG-PFPPVPPPPSSGEAVAPPSTSAAA----LSRPSGAATTTA---AGTSATAA 433
P PP+G P P P PP + ++ A P A LS P A T A S A
Sbjct: 667 TP--PPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGA 724
Query: 434 SATASGPGSGS-------------APEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
A ++GP + + P+A P P PP P P PP+ A
Sbjct: 725 PALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP------PSPQQMPPL--EKAR 776
Query: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQI-----NQYLTVLASLGPPR 535
AG+ L +E + +LL A +Q+ Q V AS+
Sbjct: 777 IAGVGSLPLSGVE--------------EKMFSLLKRAKVQLFKIDQQQQQKVAASM---- 818
Query: 536 PATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPE 577
P + EE A V + + S + + P PE
Sbjct: 819 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPE 860
Score = 47.8 bits (112), Expect = 3e-05
Identities = 79/315 (25%), Positives = 112/315 (35%), Gaps = 45/315 (14%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQP-PNFPQGLLPPFPPGMFPLWPPMGPF 391
VLR + P P EPA PP PP P P P + +L L + P
Sbjct: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
Query: 392 PPVPPPPSSGEAVAPPSTSAAALSRP----SGAATTTAAGTSATAASATASGPGSGSAPE 447
PP PPPP A +PP A + RP + T + A + T G+ APE
Sbjct: 622 PPAPPPP---PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678
Query: 448 AGPAPGFPFP----PPWMG----MPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQH 499
P P P P +G + LP F P+ P A ++P AL +
Sbjct: 679 PEPPPADDSPAEPEPRAVGRTNHLSLP---RFAPVVTTPVK-AEVSPHGAPALSNGPQTQ 734
Query: 500 LEARLQSLRNIHT-LLDAAMLQINQYLTVLASLGPPRP---------------ATSVNST 543
+ LQ L+ + T LL A+ L PP P + ++
Sbjct: 735 AQL-LQPLQALQTQLLPQALPPPQPQLQ-----PPPSPQQMPPLEKARIAGVGSLPLSGV 788
Query: 544 EETATTVVAAASSTSIPSSEATTPTPGAS---PPAPEMERPPAPESVGTEEMPEDGEPDA 600
EE +++ A + AS P +ME ++ P E ++
Sbjct: 789 EEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES 848
Query: 601 AELRRRRLQKLESPV 615
E +R R ESPV
Sbjct: 849 VEAKRERPSGPESPV 863
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/145 (28%), Positives = 50/145 (34%), Gaps = 4/145 (2%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV 394
R+ P+ P P P+ PP P L PP L P + P P P PP
Sbjct: 1912 RSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPE 1971
Query: 395 PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATAS---GPGSGSAPEAGPA 451
P + SAA L + T AA A S GPG S E+ P
Sbjct: 1972 DLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPT 2031
Query: 452 PGF-PFPPPWMGMPLPPPFAFPPMP 475
+ FP + P P A P P
Sbjct: 2032 SRYIHFPVTVVSAPGLAPSATPGAP 2056
Score = 43.1 bits (100), Expect = 7e-04
Identities = 49/181 (27%), Positives = 66/181 (36%), Gaps = 35/181 (19%)
Query: 317 RSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPP----PAPHPPPLLPQPPNFPQG 372
R W++ CR+ R P + P E A++ PAP P + P
Sbjct: 1773 RCWYR-------CRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTD 1825
Query: 373 LLPPFPPGMF--------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTT 424
+L P P PL P G PP P SG + P+ S + RP G +
Sbjct: 1826 VLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSR--RPLGGVSFG 1883
Query: 425 AAGTSATAASATASGPGSGSAPEAGPAPGFPFPP-----PWMGMPLPPP--FAFPPMPVP 477
+ + +S T P G P FP PP P P PPP +A PP+
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGD-------PDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTS 1936
Query: 478 P 478
P
Sbjct: 1937 P 1937
Score = 37.4 bits (85), Expect = 0.041
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 12/75 (16%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP-GMFPLWPPMGPFPPVPP 396
+ + P P P Q P PP + P P LPP P G+ P+ + P PP PP
Sbjct: 2204 MAGEGEPVPPPVKQ----PPLPPTISPTAPT--SWTLPPGPLLGVLPVVGVVRPAPPPPP 2257
Query: 397 PP-----SSGEAVAP 406
PP SSG A P
Sbjct: 2258 PPLTLVLSSGPASPP 2272
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/142 (27%), Positives = 50/142 (35%), Gaps = 20/142 (14%)
Query: 464 PLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQ 523
PLPPP P PP TP R EG ER ++A + LR A + +
Sbjct: 160 PLPPPRLADVAPTPPK-----TPARKRGEEGTERM-VQALTELLRRAQA-PQAPRSRACE 212
Query: 524 YLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPA 583
T S G P P VV A ++ +IP E PP P + P
Sbjct: 213 PSTPRRSRGRP-PGRPAGPCRRKQQAVVVAEAAVTIPKPE---------PPPPVV---PV 259
Query: 584 PESVGTEEMPEDGEPDAAELRR 605
G+ + E P RR
Sbjct: 260 KHQTGSWKCKEGPGPGPGTPRR 281
Score = 31.6 bits (70), Expect = 2.3
Identities = 42/149 (28%), Positives = 47/149 (31%), Gaps = 45/149 (30%)
Query: 348 PADQGPPPAPHPPPLLPQPPNFPQGLLP-PFPPGMFPLWPPMGP------FPPVPPPPSS 400
P ++ PPAP P QP QGL P P W P P P P PP
Sbjct: 2131 PREESLPPAP-PLANGSQPS---QGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPK- 2185
Query: 401 GEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 460
P+TS L G AG G P PPP
Sbjct: 2186 ------PATSKIILVNKLGQVFVKMAGE------------------------GEPVPPPV 2215
Query: 461 MGMPLPP---PFAFPPMPVPPAGFAGLTP 486
PLPP P A +PP G+ P
Sbjct: 2216 KQPPLPPTISPTAPTSWTLPPGPLLGVLP 2244
>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
sapiens]
Length = 245
Score = 68.9 bits (167), Expect = 1e-11
Identities = 54/161 (33%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 336 ASLPAQSPPPPEPADQ--GPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP- 392
+S+P+ PP P+ GP P P + P P P G PFPP PP GP+P
Sbjct: 47 SSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGP--PPGPPAPFPPSGPSCPPPGGPYPA 104
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P P P P+ L RP GA T AA + +SGP + P P
Sbjct: 105 PTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTP 164
Query: 453 GFPFPPPWMGMPLPP----PFAFPPMP---VPPAGFAGLTP 486
P+P P P PP P A PP+P VPP + P
Sbjct: 165 NMPYPSPG-PYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAP 204
Score = 54.3 bits (129), Expect = 3e-07
Identities = 52/154 (33%), Positives = 58/154 (37%), Gaps = 21/154 (13%)
Query: 339 PAQSPPPPEPADQGPPPAPHPP-PLLPQP---PNFPQGLLPPFPPGMF---PLWPPMG-- 389
P +P P P GP P P+ P P LP+P P P P P G P P MG
Sbjct: 101 PYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQ 160
Query: 390 -PFPPVP-PPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPE 447
P P +P P P A PP AA P G A G A + T S P P
Sbjct: 161 YPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYP----TPG 216
Query: 448 AGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 481
P P PF P P PPMP P +
Sbjct: 217 LYPTPSNPFQVP------SGPSGAPPMPGGPHSY 244
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/141 (30%), Positives = 50/141 (35%), Gaps = 38/141 (26%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQ--PPNFPQGLLPPFPPGMFPLWPPMGPFPPVPP 396
P Q P P + P+ P L P P P G P P GM+P PP GP P P
Sbjct: 30 PPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFG---PAPTGMYPSVPPTGPPPGPPA 86
Query: 397 P-PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFP 455
P P SG + PP A + P GP P P
Sbjct: 87 PFPPSGPSCPPPGGPYPAPTVP-------------------------------GPGPTGP 115
Query: 456 FPPPWMGMP-LPPPFAFPPMP 475
+P P M P LP P+ P P
Sbjct: 116 YPTPNMPFPELPRPYGAPTDP 136
Score = 33.1 bits (74), Expect = 0.78
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
Query: 405 APPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGM- 463
+P TSA + ++P SA +S P SG P A P+ PF P GM
Sbjct: 15 SPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVP-SGLPPSATPST-VPFGPAPTGMY 72
Query: 464 PLPPPFA---FPPMPVPPAG 480
P PP PP P PP+G
Sbjct: 73 PSVPPTGPPPGPPAPFPPSG 92
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 70/256 (27%), Positives = 92/256 (35%), Gaps = 20/256 (7%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAP--PSTSAAALSRPSGAAT-TTAAGTSATAASATASGPGSGSAPEA 448
P PPP + AP P T L P G + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 449 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 508
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 509 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 568
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 569 PGASPPAPEMERPPAP 584
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/131 (33%), Positives = 51/131 (38%), Gaps = 23/131 (17%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
P EA++PP T LS PS + A P P PAP P
Sbjct: 191 PPVLEALSPPHT----LSSPSIPTPPDFIPPAPPLAFLAPPPP-----PVPAPAPPAPAS 241
Query: 458 PPWMGMPLPPP 468
P +G L PP
Sbjct: 242 PHTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/172 (30%), Positives = 63/172 (36%), Gaps = 33/172 (19%)
Query: 332 DVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
+ RAS P +SP P+ + GP P PH FP+ P P + P+
Sbjct: 270 EATRAS-PPRSPAEPKGSALGPNPEPHL--------TFPRSFKVPPPTPVRTSSIPVQEA 320
Query: 392 PPVPPPPSSGEAVAP------PSTSAAALSR--PSGAATTTAAGT-SATAASATASGPGS 442
P AP PS S+ P A G ATA ++ G
Sbjct: 321 QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 443 GSAPEAG--PAPGFPFPPPWMGMPLPPPF-----AFPPMPV------PPAGF 481
A E P P P PPP PLPPP A PP+P PPAGF
Sbjct: 381 SQADERAGTPPPAPPLPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 43.9 bits (102), Expect = 4e-04
Identities = 67/280 (23%), Positives = 94/280 (33%), Gaps = 19/280 (6%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--FPPGMFPLWPPMGPFP 392
RA P +PP P PA PPPAP PP P P + PP F P + P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P P ++ + + + + G S + PG AP++
Sbjct: 446 NPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG-SRREDRFLSHRPGPTVAPQSKEGK 504
Query: 453 GFP-FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELR---ALEGHERQHLEARLQSLR 508
P P + LP P +P G + LT E L + ++ S+R
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR 564
Query: 509 NIHTLLDAAMLQINQYLTVLASLG--PPRPATSVNSTEETAT---TVVAAASSTSIPSSE 563
I L+A + + S+G PP+P E + + P S
Sbjct: 565 QIRNELEARLSSAAE-KEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQST 623
Query: 564 ATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAEL 603
PT P A M P P + PE P A L
Sbjct: 624 TLLPTTSLQPKA--MLGPAIP----PKATPEPAIPPKATL 657
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)
Query: 365 QPPNFPQGLL-PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATT 423
+P + Q LL PP PPG P GP + PP +PPST+
Sbjct: 129 RPGQYGQDLLIPPPPPG-----PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP 183
Query: 424 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 477
+ S P + S+P P F P P + PPP PP+P P
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPP---PPVPAP 234
Score = 35.0 bits (79), Expect = 0.20
Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 13/157 (8%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV 394
+ S P PP+ P + P +L P P+ P P LWP P +
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKATPEPAIPPKATLWPATPPKATL 667
Query: 395 PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPG 453
P + +A + P+T A S P+ A+T T T+ + A SGP A
Sbjct: 668 -GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 454 FPFPPPWMGMP-----LP-----PPFAFPPMPVPPAG 480
P G P LP AFPP P G
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 529 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 585
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 586 SVGTEEMPEDGEPDAA 601
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 70/256 (27%), Positives = 92/256 (35%), Gaps = 20/256 (7%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAP--PSTSAAALSRPSGAAT-TTAAGTSATAASATASGPGSGSAPEA 448
P PPP + AP P T L P G + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 449 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 508
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 509 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 568
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 569 PGASPPAPEMERPPAP 584
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/131 (33%), Positives = 51/131 (38%), Gaps = 23/131 (17%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
P EA++PP T LS PS + A P P PAP P
Sbjct: 191 PPVLEALSPPHT----LSSPSIPTPPDFIPPAPPLAFLAPPPP-----PVPAPAPPAPAS 241
Query: 458 PPWMGMPLPPP 468
P +G L PP
Sbjct: 242 PHTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/172 (30%), Positives = 63/172 (36%), Gaps = 33/172 (19%)
Query: 332 DVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
+ RAS P +SP P+ + GP P PH FP+ P P + P+
Sbjct: 270 EATRAS-PPRSPAEPKGSALGPNPEPHL--------TFPRSFKVPPPTPVRTSSIPVQEA 320
Query: 392 PPVPPPPSSGEAVAP------PSTSAAALSR--PSGAATTTAAGT-SATAASATASGPGS 442
P AP PS S+ P A G ATA ++ G
Sbjct: 321 QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 443 GSAPEAG--PAPGFPFPPPWMGMPLPPPF-----AFPPMPV------PPAGF 481
A E P P P PPP PLPPP A PP+P PPAGF
Sbjct: 381 SQADERAGTPPPAPPLPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 43.9 bits (102), Expect = 4e-04
Identities = 67/280 (23%), Positives = 94/280 (33%), Gaps = 19/280 (6%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--FPPGMFPLWPPMGPFP 392
RA P +PP P PA PPPAP PP P P + PP F P + P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P P ++ + + + + G S + PG AP++
Sbjct: 446 NPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG-SRREDRFLSHRPGPTVAPQSKEGK 504
Query: 453 GFP-FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELR---ALEGHERQHLEARLQSLR 508
P P + LP P +P G + LT E L + ++ S+R
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR 564
Query: 509 NIHTLLDAAMLQINQYLTVLASLG--PPRPATSVNSTEETAT---TVVAAASSTSIPSSE 563
I L+A + + S+G PP+P E + + P S
Sbjct: 565 QIRNELEARLSSAAE-KEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQST 623
Query: 564 ATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAEL 603
PT P A M P P + PE P A L
Sbjct: 624 TLLPTTSLQPKA--MLGPAIP----PKATPEPAIPPKATL 657
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)
Query: 365 QPPNFPQGLL-PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATT 423
+P + Q LL PP PPG P GP + PP +PPST+
Sbjct: 129 RPGQYGQDLLIPPPPPG-----PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP 183
Query: 424 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 477
+ S P + S+P P F P P + PPP PP+P P
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPP---PPVPAP 234
Score = 35.0 bits (79), Expect = 0.20
Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 13/157 (8%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV 394
+ S P PP+ P + P +L P P+ P P LWP P +
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKATPEPAIPPKATLWPATPPKATL 667
Query: 395 PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPG 453
P + +A + P+T A S P+ A+T T T+ + A SGP A
Sbjct: 668 -GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 454 FPFPPPWMGMP-----LP-----PPFAFPPMPVPPAG 480
P G P LP AFPP P G
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 529 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 585
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 586 SVGTEEMPEDGEPDAA 601
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 68.6 bits (166), Expect = 2e-11
Identities = 70/256 (27%), Positives = 92/256 (35%), Gaps = 20/256 (7%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAP--PSTSAAALSRPSGAAT-TTAAGTSATAASATASGPGSGSAPEA 448
P PPP + AP P T L P G + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 449 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 508
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 509 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 568
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 569 PGASPPAPEMERPPAP 584
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/131 (33%), Positives = 51/131 (38%), Gaps = 23/131 (17%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
P EA++PP T LS PS + A P P PAP P
Sbjct: 191 PPVLEALSPPHT----LSSPSIPTPPDFIPPAPPLAFLAPPPP-----PVPAPAPPAPAS 241
Query: 458 PPWMGMPLPPP 468
P +G L PP
Sbjct: 242 PHTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/172 (30%), Positives = 63/172 (36%), Gaps = 33/172 (19%)
Query: 332 DVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
+ RAS P +SP P+ + GP P PH FP+ P P + P+
Sbjct: 270 EATRAS-PPRSPAEPKGSALGPNPEPHL--------TFPRSFKVPPPTPVRTSSIPVQEA 320
Query: 392 PPVPPPPSSGEAVAP------PSTSAAALSR--PSGAATTTAAGT-SATAASATASGPGS 442
P AP PS S+ P A G ATA ++ G
Sbjct: 321 QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 443 GSAPEAG--PAPGFPFPPPWMGMPLPPPF-----AFPPMPV------PPAGF 481
A E P P P PPP PLPPP A PP+P PPAGF
Sbjct: 381 SQADERAGTPPPAPPLPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 43.9 bits (102), Expect = 4e-04
Identities = 67/280 (23%), Positives = 94/280 (33%), Gaps = 19/280 (6%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--FPPGMFPLWPPMGPFP 392
RA P +PP P PA PPPAP PP P P + PP F P + P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P P ++ + + + + G S + PG AP++
Sbjct: 446 NPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG-SRREDRFLSHRPGPTVAPQSKEGK 504
Query: 453 GFP-FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELR---ALEGHERQHLEARLQSLR 508
P P + LP P +P G + LT E L + ++ S+R
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR 564
Query: 509 NIHTLLDAAMLQINQYLTVLASLG--PPRPATSVNSTEETAT---TVVAAASSTSIPSSE 563
I L+A + + S+G PP+P E + + P S
Sbjct: 565 QIRNELEARLSSAAE-KEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQST 623
Query: 564 ATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAEL 603
PT P A M P P + PE P A L
Sbjct: 624 TLLPTTSLQPKA--MLGPAIP----PKATPEPAIPPKATL 657
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/114 (28%), Positives = 43/114 (37%), Gaps = 9/114 (7%)
Query: 365 QPPNFPQGLL-PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATT 423
+P + Q LL PP PPG P GP + PP +PPST+
Sbjct: 129 RPGQYGQDLLIPPPPPG-----PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP 183
Query: 424 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 477
+ S P + S+P P F P P + PPP PP+P P
Sbjct: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPP---PPVPAP 234
Score = 35.0 bits (79), Expect = 0.20
Identities = 42/157 (26%), Positives = 56/157 (35%), Gaps = 13/157 (8%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV 394
+ S P PP+ P + P +L P P+ P P LWP P +
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLG-PAIPPKATPEPAIPPKATLWPATPPKATL 667
Query: 395 PPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPG 453
P + +A + P+T A S P+ A+T T T+ + A SGP A
Sbjct: 668 -GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
Query: 454 FPFPPPWMGMP-----LP-----PPFAFPPMPVPPAG 480
P G P LP AFPP P G
Sbjct: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 529 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 585
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 586 SVGTEEMPEDGEPDAA 601
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 67.4 bits (163), Expect = 4e-11
Identities = 59/168 (35%), Positives = 62/168 (36%), Gaps = 60/168 (35%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFP---QGLLPPF-----------PPGMFPLWP-- 386
PPPP PA Q PP P PP P PP P Q L PP PP +FP P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFG 285
Query: 387 --PMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGS 444
P+GP PP PPPP G P P G
Sbjct: 286 QPPLGPLPPGPPPPVPGYGPPPGPPP-----------------------------PQQGP 316
Query: 445 APEAGPAPGFPFPPPWMGMPL----------PPPFAFPPMP-VPPAGF 481
P GP P P PP +G PL PPP A PP P V PA F
Sbjct: 317 PPPPGPFP--PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 362
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/117 (37%), Positives = 47/117 (40%), Gaps = 7/117 (5%)
Query: 367 PNFPQGLLPPFPPGMFPLWPPMG-PFPPVPP-PPSSGEAVAPPSTSAAAL-SRPSGAATT 423
P P G PPFP G P PP+G P PP PP PP G+ + PP RP
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
Query: 424 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
GP P GP PG PPP P PPP FPP P P G
Sbjct: 280 PGQPFGQPPLGPLPPGP-PPPVPGYGPPPG---PPPPQQGPPPPPGPFPPRPPGPLG 332
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/138 (36%), Positives = 53/138 (38%), Gaps = 23/138 (16%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
LP PP D+ PPP P QPP L P PPG P P GP PP PPP
Sbjct: 259 LPPPLAGPPNRGDRPPPPVLFPGQPFGQPP------LGPLPPGPPPPVPGYGP-PPGPPP 311
Query: 398 PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASAT-ASGPGSGSAPEAGPAPGFPF 456
P G PP RP G G T A GP G+ P A F
Sbjct: 312 PQQG----PPPPPGPFPPRPPG-----PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 362
Query: 457 PPPW-MGMPL-----PPP 468
PPP GMP PPP
Sbjct: 363 PPPTNSGMPTSDSRGPPP 380
Score = 58.2 bits (139), Expect = 2e-08
Identities = 41/99 (41%), Positives = 45/99 (45%), Gaps = 23/99 (23%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM---------GPFPP 393
PPPP P GPPP P PP P P P G PP PPG PL PP+ GP P
Sbjct: 296 PPPPVPG-YGPPPGPPPPQQGPPP---PPGPFPPRPPG--PLGPPLTLAPPPHLPGPPPG 349
Query: 394 VPPP-PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSAT 431
PPP P A PP T+ SG T+ + G T
Sbjct: 350 APPPAPHVNPAFFPPPTN-------SGMPTSDSRGPPPT 381
Score = 47.4 bits (111), Expect = 4e-05
Identities = 46/138 (33%), Positives = 50/138 (36%), Gaps = 46/138 (33%)
Query: 350 DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPST 409
D+ P PA P PP FP G PP PP L PP P PP PPPP G+ + PP
Sbjct: 215 DRFPGPAGPGGP----PPPFPAGQTPPRPP----LGPPGPPGPPGPPPP--GQVLPPP-- 262
Query: 410 SAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA-PGFPFPPPWMGMPLPPP 468
A P G P PG PF P +G PLPP
Sbjct: 263 --------------------------LAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPG 295
Query: 469 FAFPPMPVPPAGFAGLTP 486
P PP G P
Sbjct: 296 ------PPPPVPGYGPPP 307
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/138 (31%), Positives = 48/138 (34%), Gaps = 30/138 (21%)
Query: 339 PAQSPPPP-------EPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP---PGMFPLWPP- 387
P Q PPPP P GPP PPP LP P P G PP P P FP PP
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP---PPGAPPPAPHVNPAFFP--PPT 366
Query: 388 ---------MGPFPPVP---PPPSSGEAVAPPSTSAAALSRPSGAA--TTTAAGTSATAA 433
GP P P PPP PP P A A ++
Sbjct: 367 NSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISS 426
Query: 434 SATASGPGSGSAPEAGPA 451
SA + SA + G A
Sbjct: 427 SAISRAVSDASAGDYGSA 444
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 67.4 bits (163), Expect = 4e-11
Identities = 69/246 (28%), Positives = 83/246 (33%), Gaps = 41/246 (16%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PPP P PP PP PP P P P + PF P P PP
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 399 SSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 458
AP S A+ PS A+ + P S +AP P P P
Sbjct: 448 ----VQAPFSPPASPPVSPS--------------ATPPSQAPPSLAAPPLQVPPSPPASP 489
Query: 459 PWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAM 518
P PPP A PP+ PP A P+ AL Q L + S +A
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 519 LQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEM 578
L ++ T PP A V AA +P P+P ASP
Sbjct: 550 LPMSPLAT------PPPQAPP-----------VLAAPLLQVP------PSPPASPTLQAP 586
Query: 579 ERPPAP 584
RPP P
Sbjct: 587 RRPPTP 592
Score = 66.6 bits (161), Expect = 6e-11
Identities = 60/171 (35%), Positives = 65/171 (38%), Gaps = 37/171 (21%)
Query: 336 ASLPAQSPPPPE-PADQGPPPAPHPPPLLP---QPPNFPQGLL----------PPFPPGM 381
A+ P Q+PP P Q PP P PPL P P P L PP PP
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 382 FPLWPPMGPFPPVPP---PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATAS 438
P PP PPV P PPS APPS +A L P + SAT
Sbjct: 450 APFSPPAS--PPVSPSATPPSQ----APPSLAAPPLQVPPSPPASPPMSPSATP------ 497
Query: 439 GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPP---MPVPPAGFAGLTP 486
P P A P PPP PP A PP +P PPA F G P
Sbjct: 498 -PPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPSPPASFPGQAP 543
Score = 59.7 bits (143), Expect = 8e-09
Identities = 72/257 (28%), Positives = 91/257 (35%), Gaps = 45/257 (17%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP PPM
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPM 491
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 448
P PPP + APP A P A A S AS PG +
Sbjct: 492 SP-SATPPPQAPPPLAAPPLQLA---KPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547
Query: 449 GPAPGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQS 506
P P PPP PP A P + VPP+ A T LQ+
Sbjct: 548 ASLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQA 585
Query: 507 LRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS---- 562
R T + + LA PP P+ S +ST ++S+TS P
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Query: 563 EATTPTPGASPPAPEME 579
++ A+ P P+ E
Sbjct: 646 DSGPEGGAAASPPPDAE 662
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/311 (25%), Positives = 100/311 (32%), Gaps = 40/311 (12%)
Query: 336 ASLPAQSPPP-PEPADQGPPPAPHPPPLLPQ---PPNFPQGLLPP-----FPPGMFPLWP 386
A+ P+Q+PP P Q PP P PP+ P PP P L P PP P
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Query: 387 PMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSG--- 443
P +P PP+S AP S SA+ P A A P +
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583
Query: 444 SAPEAGPAPG--FPFPPPWMGMPLPPPFAFPPMPVPPAGFAG-----------LTPEELR 490
AP P PG P + + L P PP P + +G TPEELR
Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
Query: 491 ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPP------RPATSVNSTE 544
+ A + AA + LA G P PAT S +
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSR--GPAPPLAFRGAPGAPLPWPPATGPGSAD 701
Query: 545 ETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELR 604
T E+ TP PGA P P + G P A L
Sbjct: 702 GLCTIY-------ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 754
Query: 605 RRRLQKLESPV 615
L L++ V
Sbjct: 755 ELPLGALQASV 765
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/294 (27%), Positives = 102/294 (34%), Gaps = 45/294 (15%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM-------FPLWP 386
L+A P Q PP + A P P P P Q PP P L
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336
Query: 387 PMGPFPPVPP-PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA 445
P+ PP P PPS +PP+T PS A T+ + T S S P S A
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATP------PSQATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 446 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQ 505
AP PP P PP A PP+ + A +P+ AL H Q
Sbjct: 391 TPPPQAPPALALPPLQAPPSPP--ASPPL----SPLATPSPQAPNALAVHLLQ------- 437
Query: 506 SLRNIHTLLDAAMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEA 564
A V A PP P S ++T + AA +P S
Sbjct: 438 -----------APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Query: 565 TTP--TPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 616
+P +P A+PP P+ P A + + P P L LQ L SP A
Sbjct: 487 ASPPMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPA 536
Score = 43.5 bits (101), Expect = 6e-04
Identities = 59/223 (26%), Positives = 78/223 (34%), Gaps = 32/223 (14%)
Query: 359 PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPST---SAAALS 415
P P P P + G+ P P PP P S + + ST S AA
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 416 RPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 475
RPS + + ++SAT + S P A P P A P P
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--------------AHPSQP 272
Query: 476 VPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR 535
P G L P ++ L L ++ L L S PP
Sbjct: 273 -KPKGLQALRPPQVTPPRKDAAPALGP-----------LSSSPLATPSPSAALQSQAPPT 320
Query: 536 -PATSVNS--TEETATTVVAAASSTSIPSSEATTPTPGASPPA 575
PAT +S T + AT + A S S P S T P+P A+PP+
Sbjct: 321 LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
Score = 38.5 bits (88), Expect = 0.018
Identities = 59/233 (25%), Positives = 77/233 (33%), Gaps = 33/233 (14%)
Query: 379 PGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATAS 438
PG+ PP P PP P P++ + +A A+ R A G + SA +
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLG----AAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 439 GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT--PEELRALEGHE 496
GP + SA + P P G PP P PV G A T P L G +
Sbjct: 78 GP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL----GQK 132
Query: 497 RQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASS 556
+ A R A+ P R A S + +T+ S
Sbjct: 133 GLRISAEETVARG------------------KATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 557 TSIPSSEATTPTPGASPPAPEME-RPPAP---ESVGTEEMPEDGEPDAAELRR 605
S A G PAP RPP +SV + EP A RR
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 67.4 bits (163), Expect = 4e-11
Identities = 69/246 (28%), Positives = 83/246 (33%), Gaps = 41/246 (16%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PPP P PP PP PP P P P + PF P P PP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 399 SSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 458
AP S A+ PS A+ + P S +AP P P P
Sbjct: 409 ----VQAPFSPPASPPVSPS--------------ATPPSQAPPSLAAPPLQVPPSPPASP 450
Query: 459 PWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAM 518
P PPP A PP+ PP A P+ AL Q L + S +A
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 519 LQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEM 578
L ++ T PP A V AA +P P+P ASP
Sbjct: 511 LPMSPLAT------PPPQAPP-----------VLAAPLLQVP------PSPPASPTLQAP 547
Query: 579 ERPPAP 584
RPP P
Sbjct: 548 RRPPTP 553
Score = 66.6 bits (161), Expect = 6e-11
Identities = 60/171 (35%), Positives = 65/171 (38%), Gaps = 37/171 (21%)
Query: 336 ASLPAQSPPPPE-PADQGPPPAPHPPPLLP---QPPNFPQGLL----------PPFPPGM 381
A+ P Q+PP P Q PP P PPL P P P L PP PP
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 382 FPLWPPMGPFPPVPP---PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATAS 438
P PP PPV P PPS APPS +A L P + SAT
Sbjct: 411 APFSPPAS--PPVSPSATPPSQ----APPSLAAPPLQVPPSPPASPPMSPSATP------ 458
Query: 439 GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPP---MPVPPAGFAGLTP 486
P P A P PPP PP A PP +P PPA F G P
Sbjct: 459 -PPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPSPPASFPGQAP 504
Score = 59.7 bits (143), Expect = 8e-09
Identities = 72/257 (28%), Positives = 91/257 (35%), Gaps = 45/257 (17%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP PPM
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPM 452
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 448
P PPP + APP A P A A S AS PG +
Sbjct: 453 SP-SATPPPQAPPPLAAPPLQLA---KPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 449 GPAPGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQS 506
P P PPP PP A P + VPP+ A T LQ+
Sbjct: 509 ASLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQA 546
Query: 507 LRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS---- 562
R T + + LA PP P+ S +ST ++S+TS P
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 563 EATTPTPGASPPAPEME 579
++ A+ P P+ E
Sbjct: 607 DSGPEGGAAASPPPDAE 623
Score = 56.6 bits (135), Expect = 7e-08
Identities = 76/292 (26%), Positives = 104/292 (35%), Gaps = 38/292 (13%)
Query: 337 SLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPP 396
SL + + P PA GP + P P P+ P+ P G+ L PP PP
Sbjct: 232 SLSSSATPLSSPARSGP--SARGTPRAPAHPSQPK------PKGLQALRPPQ----VTPP 279
Query: 397 PPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA----P 452
+ A+ P S+S A PS + +A + T S A+ P + P
Sbjct: 280 RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339
Query: 453 GFPFPPPWMGMPLPPP-----FAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSL 507
F PP + PPP A PP+ PP+ A L L
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA------ 393
Query: 508 RNIHTLLDAAMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEATT 566
+H L A V A PP P S ++T + AA +P S +
Sbjct: 394 --VHLL--QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 567 P--TPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 616
P +P A+PP P+ P A + + P P L LQ L SP A
Sbjct: 450 PPMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPA 497
Score = 55.1 bits (131), Expect = 2e-07
Identities = 80/311 (25%), Positives = 100/311 (32%), Gaps = 40/311 (12%)
Query: 336 ASLPAQSPPP-PEPADQGPPPAPHPPPLLPQ---PPNFPQGLLPP-----FPPGMFPLWP 386
A+ P+Q+PP P Q PP P PP+ P PP P L P PP P
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Query: 387 PMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSG--- 443
P +P PP+S AP S SA+ P A A P +
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544
Query: 444 SAPEAGPAPG--FPFPPPWMGMPLPPPFAFPPMPVPPAGFAG-----------LTPEELR 490
AP P PG P + + L P PP P + +G TPEELR
Sbjct: 545 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604
Query: 491 ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPP------RPATSVNSTE 544
+ A + AA + LA G P PAT S +
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSR--GPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Query: 545 ETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELR 604
T E+ TP PGA P P + G P A L
Sbjct: 663 GLCTIY-------ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715
Query: 605 RRRLQKLESPV 615
L L++ V
Sbjct: 716 ELPLGALQASV 726
Score = 42.7 bits (99), Expect = 0.001
Identities = 78/324 (24%), Positives = 104/324 (32%), Gaps = 81/324 (25%)
Query: 330 RMDVLRASLPAQSPPPPEPA--DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPL--- 384
+ D +A A++P P PP +P PPP P P + L G PL
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAER 61
Query: 385 ------------WPPMGPFPPVPPPPSSGEAVAPP--STSAAALSRPSGAATTTAAGT-- 428
P GP PP S APP +TS +S P A+ TT G
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 429 ---------------SATAASATASGPGSGSAPEAGPAPGFPFPP---------PWMGMP 464
AT A ++ +GP PG P P +G+P
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 181
Query: 465 LPPPFAFPPMPVP------------------------PAGFAGLTPEELRALEGHERQHL 500
P P A P P P+ GL R+L L
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS-SATPL 240
Query: 501 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR---------PATSVNSTEETATTVV 551
+ +S + A L +L PP+ PA S+ AT
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 552 AAASSTSIPSSEATTPTPGASPPA 575
+A S S P S T P+P A+PP+
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPS 324
Score = 38.9 bits (89), Expect = 0.014
Identities = 63/240 (26%), Positives = 73/240 (30%), Gaps = 50/240 (20%)
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSAT 431
GLL P PPG P PPPP + A+ R GAA A
Sbjct: 23 GLLTPRPPGS-----------PRPPPPVTPAAL-----------RVLGAAGAVGRKPLAE 60
Query: 432 AASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT--PEEL 489
A SAP AGP P G PP P PV G A T P L
Sbjct: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120
Query: 490 RALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATT 549
G + + A R A+ P R A S + +T+
Sbjct: 121 ----GQKGLRISAEETVARG------------------KATEAPKRSALSAGARRDTSGP 158
Query: 550 VVAAASSTSIPSSEATTPTPGASPPAPEME-RPPAP---ESVGTEEMPEDGEPDAAELRR 605
S S A G PAP RPP +SV + EP A RR
Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 67.4 bits (163), Expect = 4e-11
Identities = 58/151 (38%), Positives = 67/151 (44%), Gaps = 17/151 (11%)
Query: 339 PAQSPPPPE--PADQGPPPAPHPPPLLPQPPN------FPQGLLPPFPPGMFPLWPPMGP 390
PA +PP P+ PA P AP PP P P P+G P PP P P GP
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA--PTPPAATPPSPKGGP 1000
Query: 391 FPPVPPPPSSGEAVAPPST--SAAALSRPSGAATTTAAGTSATAAS--ATASGPGSGSAP 446
P P + AV PPS S AA P GA+T AA + S AT G+ + P
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 447 EAG-PAP-GFPFPPPWMGMPLPPPFAFPPMP 475
A P+P G P P G P PP A PP P
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPA-ATPPSP 1090
Score = 65.9 bits (159), Expect = 1e-10
Identities = 73/268 (27%), Positives = 89/268 (33%), Gaps = 59/268 (22%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
PA +PP P+ PPP P PP+ GL P P G P P PP
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG--------APTTPAATPP 1180
Query: 399 SSGEAVAPPS------TSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA---PEAG 449
S +A PS T AA P G T + + T +AT P G A P+
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 450 PAPGFPFPPPWMGMPLPPP---FAFPPMPVPPAGFAGL-TPEELRALEGHERQHLEARLQ 505
P PP G P PP PP PP+ GL TP A
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP----------- 1289
Query: 506 SLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEAT 565
A + PP P ++ AA+ S S T
Sbjct: 1290 -----------------------AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 566 TPTPGASPPAPEMERPPAPESVGTEEMP 593
P GA P P PP+P+ GT +P
Sbjct: 1327 PPPKGA--PTPPAVTPPSPK--GTPTLP 1350
Score = 65.5 bits (158), Expect = 1e-10
Identities = 71/272 (26%), Positives = 88/272 (32%), Gaps = 55/272 (20%)
Query: 339 PAQSPPPPE------PADQGPPPAPHPPPLLPQP---PNFPQGLLPPFPPGMFPLWPPMG 389
PA +PP P+ P +G P P LP P P P P PP P P G
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093
Query: 390 PFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 449
P P P A PPS + P A TT A T + A+ P G+
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 450 PAPGFPFPPPWMGMPLPPPFAFP--PMPVPPAGFAGL-TPEELRALEGHERQHLEARLQS 506
P P P G+ PPP P P PP+ GL TP A
Sbjct: 1154 ATP----PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA--------------- 1194
Query: 507 LRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATT 566
+ PP P + + AA+ S P T
Sbjct: 1195 -------------------PTTPAATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGLAT 1234
Query: 567 PTPGASPPAPEMERPPAPESVGTEEMPEDGEP 598
P+P +P P PP+P+ G P G P
Sbjct: 1235 PSPKGAPTTP-AATPPSPKG-GPATPPPKGAP 1264
Score = 64.7 bits (156), Expect = 2e-10
Identities = 79/286 (27%), Positives = 96/286 (33%), Gaps = 60/286 (20%)
Query: 336 ASLPAQSPPPPEPADQG--PPPAPHPP-----PLLPQPPN--FPQGLLPPFPPGMFPLWP 386
A+LP+ P P+ +G PPA PP P P P P PP P G P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 387 PMG-PFPP--VPPPPSSGEAVAP----PSTSAAALSRPSGAATTTAAGTSATAASATASG 439
G P P PP P G A P P+T AA P G T + T +AT
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181
Query: 440 PGSGSA---PEAGP-APGFPFPPPWMGMPLPPPFAFP--PMPVPPAGFAGL-TPEELRAL 492
P G A P+ P P P P G+ P P P P PP+ GL TP A
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA- 1240
Query: 493 EGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVA 552
+ PP P +
Sbjct: 1241 ---------------------------------PTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 553 AASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEP 598
AA+ S+ AT P GA P P + PP+P+ G P G P
Sbjct: 1268 AATPPSLKGGLATPPHKGA--PNPAVVTPPSPKG-GPATSPPKGAP 1310
Score = 62.0 bits (149), Expect = 2e-09
Identities = 77/295 (26%), Positives = 110/295 (37%), Gaps = 55/295 (18%)
Query: 336 ASLPAQSPPPPEPADQG----PPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
+S +PP P+ +G PP+P P +P P P P + PL P P
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS------PAVIPLSPKKAPA 1417
Query: 392 PPVP----PPPSSGEAVAPPST-----SAAALSRPSGAATTTAAGTSATAASATASGPGS 442
PV PS G+ P T A A S P G T ++ T + T P
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 443 GSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPEELRALEGHERQHLE 501
AP+ P P P P P +P V P+ +P+E+ A R +
Sbjct: 1478 PPAPKQVATSSSPKKAP----ATPAPMGAPTLPAVIPS-----SPKEVPATPSSRRDPIA 1528
Query: 502 --ARLQSLRNIHTLLDAAMLQINQYLTVLA-----SLGPPRPATSVNSTEETATTVVAAA 554
A L S + TL L I +TV + ++ P+ A + S++E ++
Sbjct: 1529 PTATLLSKKTPATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 555 SS----------------TSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 593
S+ TS EA TP P +PP+PE + P P GT P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPE-KGPATPAPKGTPTSP 1640
Score = 61.2 bits (147), Expect = 3e-09
Identities = 74/282 (26%), Positives = 95/282 (33%), Gaps = 59/282 (20%)
Query: 339 PAQSPPP-----PEPADQGPPPAPHPPPLLPQPPNFP-QGLLPPFPPGMFPLWPPMG-PF 391
P ++P P P P + PAP P L + P + P P G+ P G P
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941
Query: 392 PP--VPPPPSSGEAVA----PPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSA 445
PP PP P G A P+ AA P G T + + T +AT P G A
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 446 ---PEAGPAPGFPFPPPWMGMPLPPPF----AFPPMPVPPA--GFAGLTPEELRALEGHE 496
P+ P P PP G P PF + PP PP+ G TP
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP---------- 1051
Query: 497 RQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASS 556
L T A+L P+ + S + T A S
Sbjct: 1052 ----------------------LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 557 TSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEP 598
P TP+P + P P PP+P+ G P G P
Sbjct: 1090 ---PKGGPATPSPKGA-PMPPAATPPSPKG-GLATPPHKGAP 1126
Score = 60.8 bits (146), Expect = 3e-09
Identities = 76/284 (26%), Positives = 99/284 (34%), Gaps = 80/284 (28%)
Query: 336 ASLPAQSPPP--------------PEPADQGPP-----PAPHPPPLLPQPPNFPQGLLPP 376
A P + PP P PA PP PA PP P PP PP
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP----AATPP 1318
Query: 377 FPPGMFPLWPPMG-PFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASA 435
P G PP G P PP PPS P+T+ ++ G TT ++ T +A
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS----KGGPTTPSSKEGPTPPAA 1374
Query: 436 TASGPGSGS----APEAGPAPGFPFPPPWMGMPLP-PPFAFPPMPVPPAGFAGLTPEELR 490
T S G + +P+ GPA P P +P P P PV G A TP +
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA--TPSK-- 1430
Query: 491 ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTV 550
L PP T V+ + AT+
Sbjct: 1431 --------------------------------------GDLTPP-AVTPVSLKKAPATSA 1451
Query: 551 VAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPE 594
+T PSS+ P +PP+P + PPAP+ V T P+
Sbjct: 1452 PKGGPAT--PSSKGDPTLPAVTPPSP--KEPPAPKQVATSSSPK 1491
Score = 60.5 bits (145), Expect = 5e-09
Identities = 71/275 (25%), Positives = 93/275 (33%), Gaps = 33/275 (12%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP------PGMFPLWPPMGPFP 392
PA +PP P+ P P P PP+ GL P P P P P G
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 393 PVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 452
P P + A PPS + P A T A T + A+ P G+ A P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 453 ----GFPFPPPWMGMPLPPPFAFPPMP------VPPAGFAGLTPEELRALEGHERQHLEA 502
G P P G P PP A PP P PP G TP + L A
Sbjct: 1295 PSPKGGPATSPPKGAPTPPA-ATPPSPKGSPGTPPPKG--APTPPAVTPPSPKGTPTLPA 1351
Query: 503 RLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS 562
S + T T + GP PA + + A T + +IPS
Sbjct: 1352 TTPSSKGGPT-------------TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 563 EATTPTPGASPPAPEMERPPAPESVGTEEMPEDGE 597
+ +P P +P+ + P P + P G+
Sbjct: 1399 KGDPTSPAVIPLSPK-KAPATPVTREGAATPSKGD 1432
Score = 57.0 bits (136), Expect = 5e-08
Identities = 81/305 (26%), Positives = 109/305 (35%), Gaps = 53/305 (17%)
Query: 339 PAQSPPPPEPADQGPPP--APHPPPLLPQPP--------------------NFPQGLLPP 376
PA +PP P+ + PPP AP PP + P P + +G PP
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 377 FP-------PGMFPLWPPMGPFPPVPPPPSSGEAVAP--PSTSAAALSRPSGAATTTAAG 427
P M P P GP P P + AV P P + A GAAT +
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 428 TSATAASATA--SGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP---------- 475
+ A + + P + SAP+ GPA P + PP PP P
Sbjct: 1433 LTPPAVTPVSLKKAPAT-SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 476 VPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLA---SLG 532
PA A + L A+ + + A S R+ + A L + LA +L
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD--PIAPTATLLSKKTPATLAPKEALI 1549
Query: 533 PPR---PATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAP-EMERPPAPESVG 588
PP P+ T A SS S A TP+ P+P E+ PPA S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Query: 589 TEEMP 593
+E P
Sbjct: 1610 PKEAP 1614
Score = 45.8 bits (107), Expect = 1e-04
Identities = 64/277 (23%), Positives = 91/277 (32%), Gaps = 65/277 (23%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
+S A SPP P+ P+P L+P P P PP + P P GP P P
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKEL-LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Query: 396 PPPSSGEAVAPPSTSAAALSRPSGAATTT----AAGTSATAASATASGPGS------GSA 445
G +PP T ++ P+ A+ T A A+ GP + A
Sbjct: 1634 ----KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA 1689
Query: 446 PEAGP---APGFPFPPPWMGMPLPPPFAFPP----------MPVPPAGFAGLTPEELRAL 492
PE+ P AP P PP P V PA + + +
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA 1749
Query: 493 EGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVA 552
+G + H + GP P S + +T + A
Sbjct: 1750 KGKDASH-----------------------------SPKGPLAPPES-----KASTPLTA 1775
Query: 553 AASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGT 589
AA +P E+ + + SPP + P AP V T
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPP---VSLPLAPSPVPT 1809
Score = 41.6 bits (96), Expect = 0.002
Identities = 54/235 (22%), Positives = 76/235 (32%), Gaps = 35/235 (14%)
Query: 364 PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAAALSRPSGAAT 422
P PP+ P+G P P + PL P PP P PS P A + + A +
Sbjct: 856 PTPPS-PKGA--PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 423 TTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF---PPMPVPPA 479
T++ A+ G + +P+ P P PP G P P + PP PP+
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 480 GFAG-LTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPAT 538
G TP A A S + GP P+
Sbjct: 973 PKGGPATPSPKGA-----PTPPAATPPSPKG----------------------GPATPSP 1005
Query: 539 SVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 593
T T S + P + + P A+PP+P+ P G P
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Score = 41.2 bits (95), Expect = 0.003
Identities = 52/193 (26%), Positives = 72/193 (37%), Gaps = 35/193 (18%)
Query: 390 PFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 449
P P +PPP S P S + A PS +T A T +S SG+A G
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPS---PSTIASTPLEVPFPQSS---SGTALPLG 94
Query: 450 PAPGFP-FPPPWMGMPLPP-------PFAFPPMPVPPAGFAGLTPEELRALEGHERQHLE 501
AP P F P +G P+ P P P + P+ A P L AL H Q
Sbjct: 95 TAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA---PLALVALAPHSVQKSS 151
Query: 502 ARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPS 561
A +L + + A+ + +T+ A + P P T++N +PS
Sbjct: 152 AFPPNL--LTSPPSVAVAESGSVITLSAPIAPSEPKTNLN----------------KVPS 193
Query: 562 SEATTPTPGASPP 574
P SPP
Sbjct: 194 EVVPNPKGTPSPP 206
Score = 39.3 bits (90), Expect = 0.011
Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 18/165 (10%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGPPPA--PHPPPLLPQPPNFPQGLLPPF------- 377
P V +S P ++P P P PA P P +P P+ + + P
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 378 -PPGMFPLWPPMGPFPPVPPP------PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSA 430
P + P + P VP P P+ EA A PS+ A S P +T G +
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA--SSPPAVTPSTYKGAPS 1595
Query: 431 TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 475
S S EA P P P G P P P P
Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640
Score = 38.5 bits (88), Expect = 0.018
Identities = 65/302 (21%), Positives = 91/302 (30%), Gaps = 35/302 (11%)
Query: 323 QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAP------HPPPLLP---QPPNFP--- 370
Q TC VL +P P P P PP H L P P P
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Query: 371 ---------QGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAA 421
+G L PL + P PP A P T LS P
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS---AGPDTPIGNLSSPVSPV 831
Query: 422 TTTAAGTSATAASATASGPGSGSAP-----EAGPAPGFPFPPPWMGMPLPPPFAFPP--- 473
+ ++ + + P + +P + P P P G+ LPP P
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
Query: 474 -MPVPPAGFAGLTPEELRALEGHERQHLEARLQSL-RNIHTLLDAAMLQINQYLTVLASL 531
+P P G A P++ AL +AR + I T +
Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
Query: 532 GPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEE 591
G P + + A T + + PS + P A+PP+P+ P P G
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK-GGPATPSPKGAPT 1010
Query: 592 MP 593
P
Sbjct: 1011 PP 1012
Score = 38.1 bits (87), Expect = 0.024
Identities = 67/294 (22%), Positives = 94/294 (31%), Gaps = 67/294 (22%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGPPP---APHPPPLLPQPP--NFPQGLLPPFPPGM 381
PT +VL A P +P P +GP + PP+ P P N +G L P
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA- 1736
Query: 382 FPLWPPMGPFPPVPPPPSSGEA----VAPPSTSAAALSRPSGAATTTAAGTSATAASATA 437
PL P + + +APP + A S P AA +AS +A
Sbjct: 1737 -PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA---STPLTAAAFEKVLPKPESASVSA 1792
Query: 438 SGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF--PPMPVPPAGFAGLTPEELRALEGH 495
+ S P A P+P PP +P P P P+ PA L P
Sbjct: 1793 APSPPVSLPLA-PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP--------- 1842
Query: 496 ERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAAS 555
L PP P + ++ +
Sbjct: 1843 -----------------------------------LIPPEPISG-GVPFQSVLVNMPTPK 1866
Query: 556 STSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQ 609
S IP PTP A P + + ES E +PE E D+ + ++ Q
Sbjct: 1867 SAGIP-----VPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Score = 36.2 bits (82), Expect = 0.092
Identities = 78/316 (24%), Positives = 112/316 (35%), Gaps = 63/316 (19%)
Query: 324 QTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP-------PL--LPQPPNFPQGLL 374
Q CP L A+ A P P P P P PL P+ P F L+
Sbjct: 54 QQCP------LSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLI 107
Query: 375 -PPFPPGMFPLWPPMGPFPPVPPPPSSGE-----AVAPPSTSAAALSRPSGAATTTAAGT 428
PP P L PM P + PSS A+AP S ++ P+ + +
Sbjct: 108 GPPISPAALALASPMIA-PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAV 166
Query: 429 SATAASATASGPGSGSAPEA--GPAPGFPFPPPWMGMPLPP------PF-AFPPMPVPPA 479
+ + + T S P + S P+ P P P G P PP P+ PM +
Sbjct: 167 AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMASIQS 225
Query: 480 GFAGL---TPEELRALEGHERQH--LEARLQSLRNIHTLL-------DAAMLQINQYLTV 527
G A L TP A+ + + + + L S +N +L AA+ Q L V
Sbjct: 226 GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285
Query: 528 LAS----LGPPRP---------------ATSVNSTEETATTVVAAASSTSIPSSEATTPT 568
+ S GP P +S S + T +A S ++ + +
Sbjct: 286 VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345
Query: 569 PGASPPAPEMERPPAP 584
GAS P+ PP P
Sbjct: 346 TGASYPSQRSVIPPLP 361
Score = 33.9 bits (76), Expect = 0.45
Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 21/207 (10%)
Query: 401 GEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP-GFPFPPP 459
GEA + L +P A T +SA + +A PG P PAP P
Sbjct: 3 GEATETVPATEQELPQPQ-AETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 460 WMGMPLPPP--FAFPPMPVP----------PAGFAGLTPEELRALEGHERQHLEARLQSL 507
P P P A P+ VP P G A P L L G L S
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 508 RNIHTL-------LDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 560
TL A++ + + +S PP TS S + V S+ P
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 561 SSEATTPTPGASPPAPEMERPPAPESV 587
S T S P + P+P +
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCI 208
Score = 32.7 bits (73), Expect = 1.0
Identities = 66/294 (22%), Positives = 105/294 (35%), Gaps = 78/294 (26%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM--FPLWPPMG--------P 390
Q+ P P+ Q +P P L P+ + L P P G + P+G
Sbjct: 564 QAAPKNSPSFQSTSSSPEIP-LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK 622
Query: 391 FPPVPPPPSSG----EAVAPPSTSAAALSR--PSGAATTTAAGTSATAASATASGPGSGS 444
P S+G ++ P+ +A L P+G A TTA GTS +A+ G+ S
Sbjct: 623 TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVS 682
Query: 445 -APEAGP------------------APGFPFP----PPWMGMPLPP--PFAFPPMPVPPA 479
AP+ P P P P P + L P P + P +PPA
Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA 742
Query: 480 GFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATS 539
G TP + ++G ++ ++L P +
Sbjct: 743 G----TPPGTKKVDG------------------------------ISHTSALAPVASSPK 768
Query: 540 VNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 593
TE++ + A ASS + A +P+P +P+ +RPP + + P
Sbjct: 769 ECPTEDSGAS--ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 67.0 bits (162), Expect = 5e-11
Identities = 73/271 (26%), Positives = 96/271 (35%), Gaps = 40/271 (14%)
Query: 343 PPPPEPADQGPPPAPHPP--PLLPQP--PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
PPPP P PPP P L P P P+ PQ PP P + + PP PPPP
Sbjct: 711 PPPPPP----PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 399 SSGEAVAPPSTSAAAL-SRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
A PP L + P+ +T T A AA T + P P A P FP
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP----VPPAKKQPAFP-- 820
Query: 458 PPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAA 517
+PP PP+PVPP L + + L + +++
Sbjct: 821 ----ASYIPPSPPTPPVPVPPP-----------TLPKQQSFCAKPPPSPLSPVPSVVKQI 865
Query: 518 MLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAA----SSTSIPSSEATTPTPGAS- 572
Q T A P N ++ V A SS +PS + P P +S
Sbjct: 866 ASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925
Query: 573 -----PPAPEMERPPAPESVGTEEMPEDGEP 598
PP+P PP P + + G P
Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Score = 65.5 bits (158), Expect = 1e-10
Identities = 62/202 (30%), Positives = 70/202 (34%), Gaps = 50/202 (24%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPP---------------------PLLPQPPNFPQ 371
+ + + P PPPP PA PP AP P P P PP P
Sbjct: 755 ITQVAPPTPPPPPPIPAPL-PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPA 813
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVP------------PPPSSGEAV-----------APPS 408
P FP P PP P P P PPPS V PP
Sbjct: 814 KKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP 873
Query: 409 TSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGM--PLP 466
T A S+P A S A A S S P P+P FP PPP + P P
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPS-SIPV--PSPDFPPPPPESSLVFPPP 930
Query: 467 PPFAFPPMPVPPAGFAGLTPEE 488
PP P P PP A TP++
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDK 952
Score = 58.5 bits (140), Expect = 2e-08
Identities = 71/288 (24%), Positives = 101/288 (35%), Gaps = 24/288 (8%)
Query: 306 PCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQ 365
P H+ S + S F T + +A + + + P PP +P P + P
Sbjct: 563 PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLV---PPLSPQPKIVTPY 619
Query: 366 PPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTA 425
+ P LPP PP P PP P PP P S AP + SAA + +T T
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS-----APSAGSAAPMF--VKYSTITR 672
Query: 426 AGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT 485
++ + A P P PP + P PPP PP P P + A L
Sbjct: 673 LQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP---PPPPTPGSAMAQLK 729
Query: 486 PEELR-ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV---N 541
P +L ++ +++I + L PP+P ++
Sbjct: 730 PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPT 789
Query: 542 STEETATTVVAAASSTSIPSSEATTPTPG-------ASPPAPEMERPP 582
ST+ A V AA T P P SPP P + PP
Sbjct: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
Score = 50.4 bits (119), Expect = 5e-06
Identities = 43/164 (26%), Positives = 55/164 (33%), Gaps = 27/164 (16%)
Query: 338 LPAQSPPPPEP---------------ADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMF 382
+ +Q PPPP P A Q PP P P P PP PP
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924
Query: 383 PLWPPMGPFPPVPPPPSSGEAVAP-------PSTSAAALSRPSGAATTTAAGTSATAASA 435
++PP P P PPP +P P + S P G +++ S+
Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 436 TASGPGSGSAPEAGPAPGFPFPPPWMGMP----LPPPFAFPPMP 475
+ + P PP G P LPPP A PP P
Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP-AAPPKP 1027
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/315 (23%), Positives = 107/315 (33%), Gaps = 66/315 (20%)
Query: 336 ASLPAQSP----PPPEPADQGPPPAPHPPPLLPQPP---------------------NFP 370
+S+P SP PPPE + PPP P P P P PP + P
Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP 966
Query: 371 QGLLPP-FPPGMFPLWPPMGPFPPVPPPPSSGEAVA---PPSTSA----------AALSR 416
G PP P + G P P PS V+ PP+ S AA +
Sbjct: 967 GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK 1026
Query: 417 P-----SGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPG---FPFPPPWMGMPLPP 467
P SG +A A SG G S E P FP PPP +PLPP
Sbjct: 1027 PGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPP 1086
Query: 468 PFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSL-------RNIHTLLDAAMLQ 520
PA F+G T ++ + +Q + ++ RN T L A +
Sbjct: 1087 IEI-------PAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEIS 1139
Query: 521 INQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEME- 579
+ + P P +S++ + SI + + + P M+
Sbjct: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199
Query: 580 ---RPPAPESVGTEE 591
PP PE + ++
Sbjct: 1200 MALPPPPPELLSDQQ 1214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,639,529
Number of Sequences: 37866
Number of extensions: 2167993
Number of successful extensions: 65702
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1046
Number of HSP's successfully gapped in prelim test: 1893
Number of HSP's that attempted gapping in prelim test: 19896
Number of HSP's gapped (non-prelim): 23116
length of query: 617
length of database: 18,247,518
effective HSP length: 108
effective length of query: 509
effective length of database: 14,157,990
effective search space: 7206416910
effective search space used: 7206416910
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.