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Search of human proteins with 27436925
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436925 synoviolin 1 isoform a [Homo sapiens]
(616 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 1258 0.0
gi|27436927 synoviolin 1 isoform b [Homo sapiens] 1253 0.0
gi|21071001 autocrine motility factor receptor [Homo sapiens] 123 4e-28
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 86 1e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 86 1e-16
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 82 1e-15
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 82 1e-15
gi|153792074 proline rich 12 [Homo sapiens] 82 2e-15
gi|160707881 formin 2 [Homo sapiens] 78 2e-14
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 77 5e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 76 1e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 73 7e-13
gi|21314654 ring finger protein 139 [Homo sapiens] 73 7e-13
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 73 7e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 72 1e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 72 1e-12
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 71 3e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 70 4e-12
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 70 4e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 69 1e-11
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 69 1e-11
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 68 2e-11
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 68 2e-11
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 68 2e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 68 3e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 4e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 67 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 4e-11
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 66 8e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 8e-11
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 1258 bits (3254), Expect = 0.0
Identities = 616/616 (100%), Positives = 616/616 (100%)
Query: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
Sbjct: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
Query: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
Sbjct: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
Query: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
Sbjct: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
Query: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
Sbjct: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
Query: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
Sbjct: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
Query: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
Sbjct: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
Query: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA 420
PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA
Sbjct: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAA 420
Query: 421 TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 480
TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF
Sbjct: 421 TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 480
Query: 481 AGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVN 540
AGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVN
Sbjct: 481 AGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVN 540
Query: 541 STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA 600
STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA
Sbjct: 541 STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA 600
Query: 601 ELRRRRLQKLESPVAH 616
ELRRRRLQKLESPVAH
Sbjct: 601 ELRRRRLQKLESPVAH 616
>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
Length = 617
Score = 1253 bits (3242), Expect = 0.0
Identities = 616/617 (99%), Positives = 616/617 (99%), Gaps = 1/617 (0%)
Query: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV
Sbjct: 1 MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKV 60
Query: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA
Sbjct: 61 MGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLA 120
Query: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI
Sbjct: 121 EDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAI 180
Query: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF
Sbjct: 181 LMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTF 240
Query: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT
Sbjct: 241 PLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVT 300
Query: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP
Sbjct: 301 GAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP 360
Query: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTS-AALSRPSGA 419
PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTS AALSRPSGA
Sbjct: 361 PLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGA 420
Query: 420 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG
Sbjct: 421 ATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 480
Query: 480 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 539
FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV
Sbjct: 481 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV 540
Query: 540 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 599
NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA
Sbjct: 541 NSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDA 600
Query: 600 AELRRRRLQKLESPVAH 616
AELRRRRLQKLESPVAH
Sbjct: 601 AELRRRRLQKLESPVAH 617
>gi|21071001 autocrine motility factor receptor [Homo sapiens]
Length = 643
Score = 123 bits (309), Expect = 4e-28
Identities = 86/316 (27%), Positives = 143/316 (45%), Gaps = 26/316 (8%)
Query: 35 YLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSW-YAVTETCLAFT 93
YL S + VL A ++ L+ K++ + FG LR +E +HL ++ W + + F
Sbjct: 76 YLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFG 135
Query: 94 VFRDDFSPRFVAL---FTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMF---- 146
V V F L+FL L +DR +++ SP H R++SL+
Sbjct: 136 VLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLL 195
Query: 147 ----LLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSE 202
L + +H H++ A E ++ + ++YV+H DL E
Sbjct: 196 SCCGLAAVCSITGYTHGMHTLAFMAA--------ESLLVTVRTAHVILRYVIHLWDLNHE 247
Query: 203 NPWDNKAVYMLYTELFTGFIKVLL-YMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTD 261
W+ K Y+ YT+ + L M + +++ + + A +++ +R V
Sbjct: 248 GTWEGKGTYVYYTDFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQR 307
Query: 262 AIMSR----RAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLR 317
I R + NM + ATPEEL ++ C IC + M A++LPC H+FH SCLR
Sbjct: 308 RIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSM-QAARKLPCGHLFHNSCLR 366
Query: 318 SWFQRQQTCPTCRMDV 333
SW ++ +CPTCRM +
Sbjct: 367 SWLEQDTSCPTCRMSL 382
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 85.9 bits (211), Expect = 1e-16
Identities = 67/181 (37%), Positives = 76/181 (41%), Gaps = 40/181 (22%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLL---PPFPPGMFPLWPP--------MGPF 391
PPPP P D PP P PPP P PP P G+ PP PG + PP + P
Sbjct: 588 PPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 645
Query: 392 PPVP-----PPPSS---GEAVAPPSTSAALSR--PSGAATTTAAGTSATAASATAS---- 437
PP+P P PSS G A+ PP +R P +AG
Sbjct: 646 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP 705
Query: 438 --------GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF--PPMPVPPAGFAGLTPEE 487
GPG P PG P PPP MGMP PPPF F P PV P GLTP++
Sbjct: 706 PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP---FGLTPKK 762
Query: 488 L 488
L
Sbjct: 763 L 763
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/168 (33%), Positives = 70/168 (41%), Gaps = 23/168 (13%)
Query: 330 RMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG 389
+ ++ S A + PP P+ PPAP PL P ++PP P PP
Sbjct: 550 KKEMASLSAAAITVPPSVPSRAPVPPAP---PL----PGDSGTIIPPPPAPGDSTTPPPP 602
Query: 390 PFPPVPPPPSSGEAV--APPST--SAALSRP---SGAATTTAAG--TSATAASATASGPG 440
P PP PPPP G +PPS A+S P SG AT + +S PG
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662
Query: 441 SGSAPEAGPAPG---FPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
+ P P PG P PPP PLP PP P P G AG+ P
Sbjct: 663 GTAIPPPPPLPGSARIPPPPP----PLPGSAGIPPPPPPLPGEAGMPP 706
Score = 33.9 bits (76), Expect = 0.45
Identities = 18/41 (43%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP 379
P PPPP P G PP PPP + PP P G P P
Sbjct: 715 PGIPPPPPFPGGPGIPP---PPPGMGMPPPPPFGFGVPAAP 752
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 85.9 bits (211), Expect = 1e-16
Identities = 67/181 (37%), Positives = 76/181 (41%), Gaps = 40/181 (22%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLL---PPFPPGMFPLWPP--------MGPF 391
PPPP P D PP P PPP P PP P G+ PP PG + PP + P
Sbjct: 597 PPPPAPGDSTTPPPPPPPP--PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP 654
Query: 392 PPVP-----PPPSS---GEAVAPPSTSAALSR--PSGAATTTAAGTSATAASATAS---- 437
PP+P P PSS G A+ PP +R P +AG
Sbjct: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP 714
Query: 438 --------GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF--PPMPVPPAGFAGLTPEE 487
GPG P PG P PPP MGMP PPPF F P PV P GLTP++
Sbjct: 715 PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP---FGLTPKK 771
Query: 488 L 488
L
Sbjct: 772 L 772
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/168 (33%), Positives = 70/168 (41%), Gaps = 23/168 (13%)
Query: 330 RMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG 389
+ ++ S A + PP P+ PPAP PL P ++PP P PP
Sbjct: 559 KKEMASLSAAAITVPPSVPSRAPVPPAP---PL----PGDSGTIIPPPPAPGDSTTPPPP 611
Query: 390 PFPPVPPPPSSGEAV--APPST--SAALSRP---SGAATTTAAG--TSATAASATASGPG 440
P PP PPPP G +PPS A+S P SG AT + +S PG
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
Query: 441 SGSAPEAGPAPG---FPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
+ P P PG P PPP PLP PP P P G AG+ P
Sbjct: 672 GTAIPPPPPLPGSARIPPPPP----PLPGSAGIPPPPPPLPGEAGMPP 715
Score = 33.9 bits (76), Expect = 0.45
Identities = 18/41 (43%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP 379
P PPPP P G PP PPP + PP P G P P
Sbjct: 724 PGIPPPPPFPGGPGIPP---PPPGMGMPPPPPFGFGVPAAP 761
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 82.0 bits (201), Expect = 1e-15
Identities = 62/182 (34%), Positives = 75/182 (41%), Gaps = 45/182 (24%)
Query: 339 PAQSPPPPEPADQGP-PPAPHPPP-------------------------------LLPQP 366
P PPP P +QGP PP H PP ++P P
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 367 PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAG 426
P P G PP P G P W PP PPPPSS A + P + + TTT+AG
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP----WQQNTTTTTTSAG 537
Query: 427 TSA-----TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFA 481
T + +A A+ PG AP+ P PP + PLPP A PP P PP G A
Sbjct: 538 TGSIPPWQQQQAAAAASPG---APQMQGNPTMVPLPPGVQPPLPPG-APPPPPPPPPGSA 593
Query: 482 GL 483
G+
Sbjct: 594 GM 595
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/94 (32%), Positives = 35/94 (37%), Gaps = 27/94 (28%)
Query: 341 QSPPPPEPADQGPPPAPHP-----------------PPLLPQP------PNFPQ----GL 373
Q PPPP P+ P P PP Q P PQ
Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
Query: 374 LPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPP 407
+ P PPG+ P PP P PP PPPP S + PP
Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPP 599
Score = 41.6 bits (96), Expect = 0.002
Identities = 72/303 (23%), Positives = 92/303 (30%), Gaps = 73/303 (24%)
Query: 320 FQR----QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLP 375
FQR Q RMD SL A+ P PA G P PL P P
Sbjct: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
Query: 376 PFPPGMF------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSA 429
P PP + P W GP P G P S P + T
Sbjct: 354 P-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGPHSFPHPLPSLTGGHGGH 411
Query: 430 TAASATASGPGSGSAPEAGP------APGFPFPPP---WMG-----------------MP 463
P P P PG PPP ++G MP
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMP 471
Query: 464 LPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQY 523
PP PP P PP+G P L ++Q +
Sbjct: 472 PPPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPP--------------------- 508
Query: 524 LTVLASLGPPRPATSVNST-----EETATTVVAAASSTSIPSSEATTPTPGASPPAPEME 578
PP P++S+ S+ ++ TT +A + SIP + ASP AP+M+
Sbjct: 509 -------PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561
Query: 579 RPP 581
P
Sbjct: 562 GNP 564
Score = 36.2 bits (82), Expect = 0.091
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 522 QYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 581
+YL+++A LG SV ST ATT +A+A P++ A P P S + RPP
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPR---PAAPANNPPP-PSLMSTTQSRPP 367
Query: 582 APESVGTEEMPEDG 595
S +E P G
Sbjct: 368 WMNSGPSESRPYHG 381
Score = 33.5 bits (75), Expect = 0.59
Identities = 30/98 (30%), Positives = 35/98 (35%), Gaps = 12/98 (12%)
Query: 323 QQTCPTCRMDVLRASLPA-QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM 381
QQ T S+P Q A G P P ++P PP G+ PP PPG
Sbjct: 526 QQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP----GVQPPLPPGA 581
Query: 382 FPLWPPMGPF---PPVPPPPSSGEAVAPPSTSAALSRP 416
P PP P +PP G P S RP
Sbjct: 582 PPPPPPPPPGSAGMMIPPRGGDG----PSHESEDFPRP 615
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 82.0 bits (201), Expect = 1e-15
Identities = 62/182 (34%), Positives = 75/182 (41%), Gaps = 45/182 (24%)
Query: 339 PAQSPPPPEPADQGP-PPAPHPPP-------------------------------LLPQP 366
P PPP P +QGP PP H PP ++P P
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 367 PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAG 426
P P G PP P G P W PP PPPPSS A + P + + TTT+AG
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP----WQQNTTTTTTSAG 537
Query: 427 TSA-----TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFA 481
T + +A A+ PG AP+ P PP + PLPP A PP P PP G A
Sbjct: 538 TGSIPPWQQQQAAAAASPG---APQMQGNPTMVPLPPGVQPPLPPG-APPPPPPPPPGSA 593
Query: 482 GL 483
G+
Sbjct: 594 GM 595
Score = 51.6 bits (122), Expect = 2e-06
Identities = 45/146 (30%), Positives = 49/146 (33%), Gaps = 42/146 (28%)
Query: 341 QSPPPPEPADQGPPPAPHP-----------------PPLLPQP------PNFPQ----GL 373
Q PPPP P+ P P PP Q P PQ
Sbjct: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
Query: 374 LPPFPPGMFPLWPPMGPFPPVPPPP-SSGEAVAPPSTSAALSRPSGAATTTAAGTSATAA 432
+ P PPG+ P PP P PP PPPP S+G APP PS
Sbjct: 566 MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN-------------- 611
Query: 433 SATASGPGSGSAPEAGPAPGFPFPPP 458
T G G P G P P PPP
Sbjct: 612 FVTMMGMGVAGMPPFGMPPAPPPPPP 637
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
LP +PPPP P G + PP P PP P + G+ + PP G PP PPP
Sbjct: 577 LPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGM-PPFG-MPPAPPP 634
Query: 398 P 398
P
Sbjct: 635 P 635
Score = 41.6 bits (96), Expect = 0.002
Identities = 72/303 (23%), Positives = 92/303 (30%), Gaps = 73/303 (24%)
Query: 320 FQR----QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLP 375
FQR Q RMD SL A+ P PA G P PL P P
Sbjct: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
Query: 376 PFPPGMF------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSA 429
P PP + P W GP P G P S P + T
Sbjct: 354 P-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGPHSFPHPLPSLTGGHGGH 411
Query: 430 TAASATASGPGSGSAPEAGP------APGFPFPPP---WMG-----------------MP 463
P P P PG PPP ++G MP
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMP 471
Query: 464 LPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQY 523
PP PP P PP+G P L ++Q +
Sbjct: 472 PPPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPP--------------------- 508
Query: 524 LTVLASLGPPRPATSVNST-----EETATTVVAAASSTSIPSSEATTPTPGASPPAPEME 578
PP P++S+ S+ ++ TT +A + SIP + ASP AP+M+
Sbjct: 509 -------PPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ 561
Query: 579 RPP 581
P
Sbjct: 562 GNP 564
Score = 36.2 bits (82), Expect = 0.091
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 522 QYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 581
+YL+++A LG SV ST ATT +A+A P++ A P P S + RPP
Sbjct: 312 EYLSLMAELGEAPVPASVGSTSGPATTPLASAPR---PAAPANNPPP-PSLMSTTQSRPP 367
Query: 582 APESVGTEEMPEDG 595
S +E P G
Sbjct: 368 WMNSGPSESRPYHG 381
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 81.6 bits (200), Expect = 2e-15
Identities = 91/294 (30%), Positives = 113/294 (38%), Gaps = 31/294 (10%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNF--PQGLLPPFPPGMFPLWPPMGP 390
+L P PP P P Q PPP P P P LP PP P PP PP + P PP P
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP-PPPLPPPPPPAMP 1510
Query: 391 FPPVPPPPSSGEAVAPPSTSAALS---------RPSGAA--TTTAAGTSATAASATASGP 439
PP PPPP++ APP AA S RP A TAA T A SG
Sbjct: 1511 SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESG- 1569
Query: 440 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPM-PVPPAGFAGLTPEELRALEGHERQH 498
G G E P + + L PP+ V A TPE ++ +RQ
Sbjct: 1570 GEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPE----IKDGQRQF 1625
Query: 499 LEAR-----LQSLRNIHTLLDAAMLQ-INQ--YLTVLASLGPPRPATSVNSTEETATTVV 550
+N + L L+ +N+ Y+ V A RP V + + V
Sbjct: 1626 CATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVS 1685
Query: 551 AAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRR 604
A SS P + A P P +P E+P PE MPE P+ L R
Sbjct: 1686 AGGSSAPPPKAPAPPPKP-ETPEKTTSEKP--PEQTPETAMPEPPAPEKPSLLR 1736
Score = 50.4 bits (119), Expect = 5e-06
Identities = 44/147 (29%), Positives = 52/147 (35%), Gaps = 19/147 (12%)
Query: 343 PPPPEPADQGPPPAPH--PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS 400
PP P D P P P +P PP P LP P P + PP PPP+
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG--LPSANSNGTPEPPLLEEKPPPTPPPAP 1465
Query: 401 GEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWM 460
PP P A + + T S P P P P P PPP
Sbjct: 1466 TPQPQPP--------PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP-PPPAMPSPPP-- 1514
Query: 461 GMPLPPPFAFPPMPVPPAGFAGLTPEE 487
PPP A P+ PP A +PE+
Sbjct: 1515 ----PPPPAAAPLAAPPEEPAAPSPED 1537
Score = 47.4 bits (111), Expect = 4e-05
Identities = 60/203 (29%), Positives = 78/203 (38%), Gaps = 44/203 (21%)
Query: 296 EEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPP 355
E ++GA LP + F +S S +Q + + R + +SL Q PP PA+ P
Sbjct: 129 ELFISGA--LPGSSTFPSSSALSAYQHPASFGS-RPFPVPSSLSLQDPPFSPPANGLLSP 185
Query: 356 ------APHPPPLLPQPPNFPQ----GLLPPFPPGMFPLW-PPMGPFPPVPPPPSSGEAV 404
P P +P F + G+L P G+ P PP P PP PPPP
Sbjct: 186 HDVLHLKPSQAPTVPSSLGFERLAGGGVLGP--AGLGPAQTPPYRPGPPDPPPP------ 237
Query: 405 APPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPL 464
R A +SA AA+A S P + A P P PPP +P
Sbjct: 238 ---------PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP----PPPERALPR 284
Query: 465 P---------PPFAFPPMPVPPA 478
P A PP P PPA
Sbjct: 285 QDTVIKHYQRPASAQPPPPPPPA 307
Score = 43.5 bits (101), Expect = 6e-04
Identities = 75/277 (27%), Positives = 88/277 (31%), Gaps = 80/277 (28%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS 400
+SPPPP P Q P PH L P+ P +LPP PP + P P P P
Sbjct: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPL-VLPPPPPQLLPSVLSHAP-SPSPSASKV 819
Query: 401 GEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWM 460
G + P+T G P PPP
Sbjct: 820 GVHLLEPAT----------------------------------------RDGAPQPPP-- 837
Query: 461 GMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQH-LEARLQSLR-NIHTLLD--AA 516
PPP PPMP+ LE H R H LE S R LD A
Sbjct: 838 ----PPPPPPPPMPL--------------QLEAHLRSHGLEPAAPSPRLRPEESLDPPGA 879
Query: 517 MLQINQYLTVL------ASLGPPR-----PATSVNSTEETATTVVAAASSTSI--PSSEA 563
M ++ L L +GPP PA + S T TSI P S
Sbjct: 880 MQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLL 939
Query: 564 TTPTPGASPPAPEMERPPAPESVGTEEMPED-GEPDA 599
P EM A + G PED G+P A
Sbjct: 940 QDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKA 976
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/181 (28%), Positives = 60/181 (33%), Gaps = 34/181 (18%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHP----------PPLLPQPPNFPQGLLPPFPPGMFPL 384
R P PPPP P PPP P P P P P+ L P P M L
Sbjct: 829 RDGAPQPPPPPPPP----PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP-PGAMQEL 883
Query: 385 WPPMGPFPPVP------PPPSSGE----AVAPPSTSAALSRPSGAATTTAAGTSATAASA 434
+ P PP P PP S G+ A PS + T+ S
Sbjct: 884 LGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEE 943
Query: 435 TASGP------GSGSAPE---AGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
+ P G G+A + AGP P G P PP P P P +G P
Sbjct: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003
Query: 486 E 486
E
Sbjct: 1004 E 1004
Score = 39.3 bits (90), Expect = 0.011
Identities = 34/128 (26%), Positives = 45/128 (35%), Gaps = 9/128 (7%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPP 393
+R S A++P + PP AP PPP P P+ PP P P PP
Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPAPPP----KPETPEKTTSEKPPEQTP--ETAMPEPP 1727
Query: 394 VPPPPSSGEAVAPPSTSAALS---RPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA 450
P PS V ++ RP T+ + S P + P+A P
Sbjct: 1728 APEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPT 1787
Query: 451 PGFPFPPP 458
PPP
Sbjct: 1788 KVKAEPPP 1795
Score = 36.2 bits (82), Expect = 0.091
Identities = 44/160 (27%), Positives = 53/160 (33%), Gaps = 28/160 (17%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLW--------PPMGPFPPVP 395
PP P PP P L PQPP P PP P G F L +G P P
Sbjct: 1305 PPLSPPKSVPPSVP-ARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLGLGCPSP 1362
Query: 396 PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATA-------SGPGSGSAPEA- 447
E T + S + + +SA + +GP S P+
Sbjct: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGP 1422
Query: 448 --GPAPGFPFPPPWMGMPL--------PPPFAFPPMPVPP 477
PA P PPP G+P PP P P PP
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP 1462
Score = 35.0 bits (79), Expect = 0.20
Identities = 36/125 (28%), Positives = 47/125 (37%), Gaps = 18/125 (14%)
Query: 340 AQSPPPPEPA----------DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG 389
A PPPPE A Q P A PPP P P + Q L +P MG
Sbjct: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPP--PPPAHALQHYL-----SCGGSYPSMG 324
Query: 390 PFPPVPPPPSSGEAVAPPSTSAALSRPSGA-ATTTAAGTSATAASATASGPGSGSAPEAG 448
+ P G +P + + + PSGA A + T AA +G G G
Sbjct: 325 HRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPII 384
Query: 449 PAPGF 453
+PG+
Sbjct: 385 QSPGY 389
Score = 33.1 bits (74), Expect = 0.77
Identities = 64/261 (24%), Positives = 94/261 (36%), Gaps = 31/261 (11%)
Query: 356 APHPPPLLPQPPNF-PQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAP---PSTSA 411
APHP L N P GL F G+ GP V S+ E+ P PS S+
Sbjct: 52 APHP--LQSYATNHHPAGLSGLFDTGLHHAGSA-GPDASVMNLISALESRGPQPGPSASS 108
Query: 412 ALSRPSGAATTTAAGTSA-TAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAF 470
LS+ + TA T T + + PGS + P + + P + P P P +
Sbjct: 109 LLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSL 168
Query: 471 ----PPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAML---QINQY 523
PP P G L+P ++ L+ + + + L L +L +
Sbjct: 169 SLQDPPFSPPANGL--LSPHDVLHLKPSQAPTVPSSL----GFERLAGGGVLGPAGLGPA 222
Query: 524 LTVLASLGPPRP-------ATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPE 576
T GPP P T N +++ AAA +S + PG PP PE
Sbjct: 223 QTPPYRPGPPDPPPPPRHLPTQFNLL-ASSSAAAAAAEQSSPQLYNFSGAAPG--PPPPE 279
Query: 577 MERPPAPESVGTEEMPEDGEP 597
P + + P +P
Sbjct: 280 RALPRQDTVIKHYQRPASAQP 300
Score = 32.3 bits (72), Expect = 1.3
Identities = 35/137 (25%), Positives = 48/137 (35%), Gaps = 19/137 (13%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQ--GLLPPFPPGMFPLWPPMGPFP 392
+A P P PE PP P +P+PP P+ LL P G P
Sbjct: 1695 KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP-APEKPSLLRPVEKEKEKEKVTRGERP 1753
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATA---------------ASATAS 437
+SG P S A +P+ + A T A +ATA
Sbjct: 1754 LRGERATSGRQTR-PERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAG 1812
Query: 438 GPGSGSAPEAGPAPGFP 454
G GS+ ++ +PG P
Sbjct: 1813 GGPPGSSSDSESSPGAP 1829
Score = 32.0 bits (71), Expect = 1.7
Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 357 PHPPPLLPQPPNF-PQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAP 406
P+ PP LP N P GL+ P P PP P PP P G +P
Sbjct: 1012 PNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Score = 30.8 bits (68), Expect = 3.8
Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 11/84 (13%)
Query: 395 PPPPSSG-----EAVAPPSTSAALSRPSGA------ATTTAAGTSATAASATASGPGSGS 443
PPPP S +++ P+ + A + SGA A + A G G G
Sbjct: 406 PPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQ 465
Query: 444 APEAGPAPGFPFPPPWMGMPLPPP 467
A + AP + PP PPP
Sbjct: 466 AQDLSKAPSYSGGPPQPPSGPPPP 489
Score = 30.8 bits (68), Expect = 3.8
Identities = 31/103 (30%), Positives = 34/103 (33%), Gaps = 37/103 (35%)
Query: 348 PADQGPP-----PAPHPPPLLPQPPNFPQ------------GLLPPFPP----------- 379
P D+G P P P PP P P P GL P PP
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
Query: 380 GMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATT 422
G+ P PP PPPP PP A S P G T+
Sbjct: 1028 GLIQSGPHQAAPPPPPPPP-------PPPAPA--SEPKGGLTS 1061
Score = 30.8 bits (68), Expect = 3.8
Identities = 44/168 (26%), Positives = 61/168 (36%), Gaps = 15/168 (8%)
Query: 441 SGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPEELRALEGHERQHL 499
+G P P P P G+ PP A P +P PP+G GL ALE E + L
Sbjct: 1301 AGLTPPLSPPKSVPPSVPARGLQPQPP-ATPAVPHPPPSGAFGLG----GALEAAESEGL 1355
Query: 500 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 559
S LD ++ + L L S SV + ++ +A S+ P
Sbjct: 1356 GLGCPSPCK---RLDE---ELKRNLETLPSFSSDE-EDSVAKNRDLQESISSAISALDDP 1408
Query: 560 --SSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRR 605
+ T TP P AP P P G +G P+ L +
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK 1456
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 78.2 bits (191), Expect = 2e-14
Identities = 53/152 (34%), Positives = 59/152 (38%), Gaps = 9/152 (5%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV---PPPPS 399
PPPP P PPP P P +P PP P +PP PP PP P P PPPP
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135
Query: 400 SGEAVAPPSTSAALSRPS-----GAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGF 453
G + PP + P GA PG G P P G
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195
Query: 454 PFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
P PPP G +PPP P M +PPA L P
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Score = 77.8 bits (190), Expect = 3e-14
Identities = 59/169 (34%), Positives = 68/169 (40%), Gaps = 29/169 (17%)
Query: 343 PPPPEPADQGPPPAPHP-------PPL----LPQPPNFPQGLLPPFPP---GMFPLWPPM 388
PPPP P PPP P P PPL +P PP P +PP PP PL PP+
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970
Query: 389 --GPFPPVPPPPSSGEAVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGS 443
PP PP P +G PP A + P GA PG+G
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
Query: 444 APEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 485
P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1076
Score = 77.4 bits (189), Expect = 4e-14
Identities = 56/158 (35%), Positives = 65/158 (41%), Gaps = 18/158 (11%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP----GMFPLWP-PMGPFPPVPPP 397
PPPP P PPP P P +P PP P +PP PP G+ P P P PP PP
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 398 PSSGEAVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGF 453
P +G PP A + P GA PG+G P P G
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1063
Query: 454 PFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 485
P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1064 PPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1098
Score = 77.4 bits (189), Expect = 4e-14
Identities = 53/150 (35%), Positives = 63/150 (42%), Gaps = 13/150 (8%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGE 402
PPPP P PPP P P +P PP P +PP PP P +G PP PP P +G
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----LPGVG-IPPPPPLPGAGI 1118
Query: 403 AVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGSAPEAG-PAPGFPFPPP 458
PP A + P GA PG+G P P G P PPP
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Query: 459 WMGMPLPPPFAFPPM---PVPPAGFAGLTP 485
G+ +PPP P + P PP AG+ P
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Score = 74.3 bits (181), Expect = 3e-13
Identities = 58/167 (34%), Positives = 66/167 (39%), Gaps = 15/167 (8%)
Query: 338 LPAQSPPPPEPADQG--PPPAPHPPPLLPQPPNFPQGLLPPFPP----GMFPLWP-PMGP 390
LP PPP P PPP P P +P PP P +PP PP G+ P P P
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
Query: 391 FPPVPPPPSSGEAVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGSAPEA 447
PP PP P G PP A + P GA PG G P
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199
Query: 448 G-PAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEG 493
P G P PPP GM +PP P P+PP G G+ P L + G
Sbjct: 1200 PLPGAGIPPPPPLPGMGIPPA---PAPPLPPPG-TGIPPPPLLPVSG 1242
Score = 73.9 bits (180), Expect = 4e-13
Identities = 54/152 (35%), Positives = 64/152 (42%), Gaps = 10/152 (6%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV---PPPPS 399
PPPP P PPP P P +P PP P +PP PP PP P P PPPP
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Query: 400 SGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG--PAPGFPFPP 457
G + PP + P G A P P G PAP P PP
Sbjct: 1169 PGAGIPPPPPLPGVGIPP-PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Query: 458 PWMGMPLPP--PFAFPPMPVPPAGFAGL-TPE 486
P G+P PP P + PP+ +P G + L TP+
Sbjct: 1228 PGTGIPPPPLLPVSGPPL-LPQVGSSTLPTPQ 1258
Score = 73.2 bits (178), Expect = 7e-13
Identities = 58/169 (34%), Positives = 71/169 (42%), Gaps = 24/169 (14%)
Query: 337 SLPAQSPPPPEPADQG-----PPPAPHPPPLLPQPPNFP-QGL--LPPFPPGMFPLWPPM 388
+LP+ + P P P QG PPP P P +P PP P G+ LPP P P PP+
Sbjct: 890 TLPSTAIPQPPPL-QGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL 948
Query: 389 --GPFPPVPPPPSSGEAVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGS 443
PP PP P +G + PP A + P GA PG+G
Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1008
Query: 444 APEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 485
P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1054
Score = 72.8 bits (177), Expect = 9e-13
Identities = 50/151 (33%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 338 LPAQSPPPPEPADQG--PPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV- 394
LP PPP P PPP P P +P PP P +PP PP PP P P
Sbjct: 1025 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 395 --PPPPSSGEAVAPPSTSAALSRP-----SGAATTTAAGTSATAASATASGPGSGSAPEA 447
PPPP G + PP + P GA PG+G P
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 448 G-PAPGFPFPPPWMGMPLPPPFAFPPMPVPP 477
P G P PPP G +PPP P +PP
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Score = 70.5 bits (171), Expect = 4e-12
Identities = 58/169 (34%), Positives = 65/169 (38%), Gaps = 30/169 (17%)
Query: 343 PPPPEPADQGPP----PAPHPPPLL------PQPPNFPQGLLPPFPP----GMFPLWPPM 388
PPPP P P P PPPL P PP P +PP PP G+ PL P
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLP 938
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRP-----SGAATTTAAGTSATAASATASGPGSGS 443
G P PPPP G A+ PP P GA PG+G
Sbjct: 939 GAGIP-PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 997
Query: 444 APEAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 485
P P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 998 PPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1043
Score = 65.1 bits (157), Expect = 2e-10
Identities = 56/167 (33%), Positives = 64/167 (38%), Gaps = 28/167 (16%)
Query: 344 PPPEPADQ------GPPPAPHPPPLLP--QPPNFPQGLLPPFPP----GMFPLWPPMGP- 390
PPP P + G P PPP LP P P +P PP M P PP P
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 391 --FPPVPPPPSSGEAVAPPSTSAALSRP---SGAATTTAAGTSATAASATASGPGSGSAP 445
PP PP P +G PP A + P GAA PG+G P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
Query: 446 EAG-PAPGFPFPPPWMGMPLPPPFAFPPM------PVPPAGFAGLTP 485
P G P PPP G +PPP PP+ P PP AG+ P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPP 1021
Score = 37.4 bits (85), Expect = 0.041
Identities = 24/56 (42%), Positives = 26/56 (46%), Gaps = 10/56 (17%)
Query: 339 PAQSPPPPEPADQGPPPAPHP---PPLLPQ-------PPNFPQGLLPPFPPGMFPL 384
PA +PP P P PPP P PPLLPQ P L PP P G+F L
Sbjct: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGL 1274
Score = 33.5 bits (75), Expect = 0.59
Identities = 38/168 (22%), Positives = 45/168 (26%), Gaps = 40/168 (23%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
A+ P + PP P AP P P + P PFP
Sbjct: 284 AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE---------------- 327
Query: 396 PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG------- 448
A P AA + GA T G A PG APE G
Sbjct: 328 ---------AGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRL 378
Query: 449 --------PAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEEL 488
P P G P P F P P+ + T +L
Sbjct: 379 GEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQL 426
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 77.0 bits (188), Expect = 5e-14
Identities = 62/169 (36%), Positives = 68/169 (40%), Gaps = 25/169 (14%)
Query: 340 AQSPPPPEPAD-------QGPPPAPHPPPLLPQPPNFPQGLLPP-FPPGMFPLWPPMGPF 391
A +PPPP + G PP PPP PP P G LPP PP M P PPM P
Sbjct: 212 ADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPP--PPMPPG 269
Query: 392 PPVPPPPSSGEAVA----------PPSTSAALSRPSGAATTTAAGTSATAASATASGPGS 441
PPS+G A P + P + A A PGS
Sbjct: 270 AAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGS 329
Query: 442 GSAPEAGPAPGFPFP-PPWMGM-PLPPPFAFP---PMPVPPAGFAGLTP 485
G P P PG P P PP MGM P PPF P P P+PP G G P
Sbjct: 330 GGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPP 378
Score = 48.5 bits (114), Expect = 2e-05
Identities = 44/138 (31%), Positives = 49/138 (35%), Gaps = 45/138 (32%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEA 403
P P G P P PPP +P P P G+ P PP P+ P GP PP G
Sbjct: 322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHP-GPMPP------HGMR 374
Query: 404 VAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPP--WMG 461
PP L P G +GP P PPP +
Sbjct: 375 GPPP-----LMPPHG-----------------YTGP--------------PRPPPYGYQR 398
Query: 462 MPLPPPFAFPPMPVPPAG 479
PLPPP P PVPP G
Sbjct: 399 GPLPPPRPTPRPPVPPRG 416
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.9 bits (185), Expect = 1e-13
Identities = 73/260 (28%), Positives = 90/260 (34%), Gaps = 44/260 (16%)
Query: 345 PPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV----PPPPSS 400
P PA+ P AP PPP P G P PP P GP PP PPP S
Sbjct: 75 PAAPAEGAPGAAPEPPPAGRARPG-GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133
Query: 401 GEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWM 460
+ AP +AA++ A A + AA A +GPG G P GP PG
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG-------- 185
Query: 461 GMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQI 520
P PAG P + L G +L N H A+ +
Sbjct: 186 -------------PGKPAG-----PGAAQTLNGS---------AALLNSHHAAAPAVSLV 218
Query: 521 NQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERP 580
N L L P +V T A + P + P A+PP P P
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP----P 274
Query: 581 PAPESVGTEEMPEDGEPDAA 600
PAP ++ G P AA
Sbjct: 275 PAPATLARPPGHPAGPPTAA 294
Score = 65.9 bits (159), Expect = 1e-10
Identities = 69/259 (26%), Positives = 96/259 (37%), Gaps = 18/259 (6%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
A+ PA S PA P P P P + Q P F PP P P P P
Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAA 269
Query: 396 PPPSSGEAVAPPSTSAALSRPSG-AATTTAAGTSATAASATASGPGSGSAPEAGPAPGFP 454
PPP PP A L+RP G A A + +A +G +G+AP PA G
Sbjct: 270 PPP-------PPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG-- 320
Query: 455 FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLD 514
P G P P A P P G +P+ + Q L A + ++
Sbjct: 321 GPAGVSGQPGPGAAAAAPAP----GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 515 AAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPA 574
M L A++ PP P T + A V + S T ++ T + A
Sbjct: 377 PTM---QGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433
Query: 575 PEMERPPA-PESVGTEEMP 592
P + +PP P ++ ++P
Sbjct: 434 PRLPQPPQNPTNIQNFQLP 452
Score = 54.3 bits (129), Expect = 3e-07
Identities = 77/294 (26%), Positives = 100/294 (34%), Gaps = 45/294 (15%)
Query: 336 ASLPAQSPPPPEPADQGPP-------PAP-HPPPLLPQPPNFPQGLLPPFPPGMFPLWPP 387
A LP P P Q PP PAP P P P P PP PP L P
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283
Query: 388 MG-------PFPPVPPPPSS---GEAVAPPSTSAALSRPSGAATTTAAGTSATAAS---- 433
G P VPPP ++ G A A P+ + A P+G + G +A A +
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343
Query: 434 -------ATASGPGSGSAPEAGPA--PGFPFPPPWMGMPLPPPFAFPPMPVP------PA 478
A+ P + + +GPA P M LP P A PP P P P
Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP-PAPGTPTGLPK 402
Query: 479 GFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATS 538
G AG + L + A L T+L + Q Q T + + P
Sbjct: 403 GAAGAVTQSLSRTPTATTSGIRATLTP-----TVLAPRLPQPPQNPTNIQNFQLPPGMVL 457
Query: 539 VNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 592
V S + A + + A T A PA PP + T + P
Sbjct: 458 VRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPV--QISTVQAP 509
Score = 53.9 bits (128), Expect = 4e-07
Identities = 76/294 (25%), Positives = 93/294 (31%), Gaps = 73/294 (24%)
Query: 340 AQSPPPPE---------PADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFP-LWPPMG 389
A+ PPPE PA P P P P P P L PG P P G
Sbjct: 124 AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183
Query: 390 PFPPVPPPPSSGEAV------------APPSTS-------AALSRPSGAATTTAAGTSAT 430
P P P P + + + A P+ S A L P AA T T
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
Query: 431 AASATASGPGSGSAP----EAGPAPGFPFPPPW-------MGMPLPPPFAFPPMPVPPA- 478
+A P + S P A PA P PPP G P PP A P +P P A
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAA 303
Query: 479 ---GFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRP 535
G AG P A G ++ A+ P P
Sbjct: 304 QNGGSAGAAPAPAPAAGG-----------------------PAGVSGQPGPGAAAAAPAP 340
Query: 536 ATSVNSTEET------ATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAP 583
S + A +AA+ S +S PT + P+P PPAP
Sbjct: 341 GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 73.2 bits (178), Expect = 7e-13
Identities = 77/290 (26%), Positives = 102/290 (35%), Gaps = 45/290 (15%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPL-------LPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
P +PPP P+ PP PP L LP PP P PP P L P P
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
Query: 392 PPVPPPPSSGEAVAPPSTSAALS------------RPSGAATTTAAGTSATAASAT--AS 437
P PP S A P AL+ P A + + + SAT +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Query: 438 GPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQ 497
P S +AP P P PP PPP A PP+ PP P
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS---------P 745
Query: 498 HLEARLQSLRNIHTLLDAAMLQI------NQYLTVLASLGPPRPATSVNSTEETATTVVA 551
+ + LL A LQ+ + ++ LA P P + + A
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 552 A-------ASSTSIPSSEATTPTPGASP--PAPEMERPPAPESVGTEEMP 592
+ + S S+P S TP P A P AP ++ PP+P + T + P
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Score = 69.3 bits (168), Expect = 1e-11
Identities = 73/255 (28%), Positives = 95/255 (37%), Gaps = 35/255 (13%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
A+ P Q PP P PA P+ PPP P P P +PP PP P+ P P P VP
Sbjct: 700 AAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 396 PPPSSGEAVAPPSTSAAL------SRPSGAATTTAAGTSATAASATASGPGSGSAPEAGP 449
P ++ PPS A+L P A A S AS PG +
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 450 APGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
P P PPP PP A P + VPP+ A T LQ+ R
Sbjct: 819 LPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQAPR 856
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS----EA 563
T + + LA PP P+ S +ST ++S+TS P ++
Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 564 TTPTPGASPPAPEME 578
A+ P P+ E
Sbjct: 917 GPEGGAAASPPPDAE 931
Score = 67.0 bits (162), Expect = 5e-11
Identities = 53/160 (33%), Positives = 63/160 (39%), Gaps = 20/160 (12%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP P+ P
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P P PPP ++ PPS A S P + T A+ P S P +
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPA--SPPMSPSATPPPRVPPLLAAPPLQVP--PSPPASL 776
Query: 449 PAPGFPFPPPWMGMPLPPPFAFPP---MPVPPAGFAGLTP 485
P PPP PP A PP +P PPA F G P
Sbjct: 777 PMSPLAKPPP----QAPPALATPPLQALPSPPASFPGQAP 812
Score = 62.0 bits (149), Expect = 2e-09
Identities = 70/259 (27%), Positives = 88/259 (33%), Gaps = 45/259 (17%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPP--NFPQGLLPPFPPGMFPLWPPMGPFPPVPPP--- 397
PP + PP PP L PP N P PP PL P PP P P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 398 --PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPF 455
P S PP T PS AT A A+ P +P A P P
Sbjct: 570 QAPPSPLTTPPPET------PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ--- 620
Query: 456 PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDA 515
PP + +P PP P + A +P+ AL H Q
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ------------------ 662
Query: 516 AMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEATTP--TPGASP 572
A V A PP P S ++T + AA +P S +P +P A+P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 573 P--------APEMERPPAP 583
P AP ++ PP+P
Sbjct: 723 PPQAPPPLAAPPLQVPPSP 741
Score = 58.5 bits (140), Expect = 2e-08
Identities = 61/203 (30%), Positives = 74/203 (36%), Gaps = 50/203 (24%)
Query: 327 PTCRMDVLRASLPAQSPPPP----------EPADQGPPPAPHPP-PLLPQPPNFPQGLLP 375
P R+ L A+ P Q PP P +P Q PP PP LP PP G P
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 376 PFPPGMFPLWPPMGPFPPVPP------------PPSSGEAVAP-------PSTSAALSR- 415
P P+ P P P PP PP+S AP P TS + R
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 416 -----------PSGAATTT-----AAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 459
PS + ++T AG S++A S G S PE G A PPP
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS---PPPD 929
Query: 460 MGMPLPPPFAFPPMPVPPAGFAG 482
+ P A+ P PP F G
Sbjct: 930 AELAACHPAAWSRGPAPPLAFRG 952
Score = 57.8 bits (138), Expect = 3e-08
Identities = 81/296 (27%), Positives = 106/296 (35%), Gaps = 38/296 (12%)
Query: 344 PPPEPADQGP---------PPAPHPPP---LLPQPPNFPQGLLPP---FPPGMFPLWPPM 388
P P P PP+P PP LP PP P PP PP P P +
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSL 383
Query: 389 GPFPPVPPPPS--SGEAVAPPS--------TSAALSRPSGAATTTAAGTSATAASATASG 438
PP+ P S S APPS + +L P+ AT + S A+ +
Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS 443
Query: 439 PGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQH 498
P S P + P P P + +P PP P + LT L+AL
Sbjct: 444 P---SRPASTPPDSPPLQAP-LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 499 LEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSI 558
+A L SL + L + L T ASL P + T A ++ +
Sbjct: 500 PQAPLSSL-IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 559 PSSEATTPTPGASPPAPEMERPP-APESVGTEEMPEDGEPDAAELRRRRLQKLESP 613
+ P P +PP+P PP P S+ T P P A L LQ L SP
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIAT---PPPQAPPA--LASPPLQGLPSP 609
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/293 (27%), Positives = 113/293 (38%), Gaps = 51/293 (17%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
++ P SP P+ +G P AP P QP P+GL PP + P P P +
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHP---SQPK--PKGLQALRPPQVTP--PRKDAAPALG 297
Query: 396 PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPF 455
P SS +A PS S +RP A AT S P + P A P+P
Sbjct: 298 PLSSS--PLATPSPSGTKARPVPPPDNAATPLPAT---LPPSPPLATPLPLAPPSPS--A 350
Query: 456 PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDA 515
PP +P PP A PP PP+ +T ++A LQ++ I
Sbjct: 351 PPSLQTLPSPP--ATPPSQAPPS----MTTPPMQA---------PPSLQTIPPI------ 389
Query: 516 AMLQINQYLTVLASLGPPRP--------ATSVNSTEETATTVVAAASSTSIPSSEATTPT 567
Q+ LT + PP P TS+ S AT S +S +
Sbjct: 390 ---QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
Query: 568 PGASPP-APEMERP---PAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVAH 616
P ++PP +P ++ P PA + T P P ++ L LQ L S +H
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQALSSLASH 498
Score = 41.2 bits (95), Expect = 0.003
Identities = 62/239 (25%), Positives = 78/239 (32%), Gaps = 40/239 (16%)
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATA 431
GLL P PPG P PPPP + A+ + A+ R A G +
Sbjct: 23 GLLTPRPPGS-----------PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 432 ASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT--PEELR 489
SA +GP + SA + P P G PP P PV G A T P L
Sbjct: 72 ESAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL- 129
Query: 490 ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTV 549
G + + A R A+ P R A S + +T+
Sbjct: 130 ---GQKGLRISAEETVARG------------------KATEAPKRSALSAGARRDTSGPT 168
Query: 550 VAAASSTSIPSSEATTPTPGASPPAPEME-RPPAP---ESVGTEEMPEDGEPDAAELRR 604
S S A G PAP RPP +SV + EP A RR
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Score = 38.1 bits (87), Expect = 0.024
Identities = 66/268 (24%), Positives = 93/268 (34%), Gaps = 28/268 (10%)
Query: 330 RMDVLRASLPAQSPPPPEPA--DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPP 387
+ D +A A++P P PP +P PPP P P + L G PL
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAER 61
Query: 388 MGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 447
G P S+ A P+ SA S + A+ A+G A A + PG S+P
Sbjct: 62 AGGIGGATIPESAPR--AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
P P G+ + A T +A E +R L A +
Sbjct: 120 ASGTTRPGPLGQKGLRIS---------------AEETVARGKATEAPKRSALSAGARRDT 164
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATT-P 566
+ T + + +G PRPA S T S S S +TT P
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE----GPRKSVSSASEHSTTEP 220
Query: 567 TPGA--SPPAPEMERPPAPESVGTEEMP 592
+P A P A + PA S+ + P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATP 248
Score = 37.4 bits (85), Expect = 0.041
Identities = 79/353 (22%), Positives = 107/353 (30%), Gaps = 80/353 (22%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQ------GPPPAPHPPPLLPQPPNFPQGLLPPFPPG 380
P R L P SP PP P G A PL + +P P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 381 MFPLWPP-MGPFPPVPPPPSSGEAV-APPSTSAA---LSRPSGAATTTAAGT-------- 427
P P PP+SG APP+ + + +S P A+ TT G
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 428 ---------SATAASATASGPGSGSAPEAGPAPGFPFPP---------PWMGMPLPPPFA 469
AT A ++ +GP PG P P +G+P P P A
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 470 FPPMPVP------------------------PAGFAGLTPEELRALEGHERQHLEARLQS 505
P P P+ GL R+L L + +S
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPARS 255
Query: 506 LRNIHTLLDAAMLQINQYLTVLASLGPPR---------PATSVNSTEETATTVVAAASST 556
+ A L +L PP+ PA S+ AT + +
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 557 SIPSSE-ATTPTPGASPPAPEM--------ERPPAPESVGTEEMPEDGEPDAA 600
+P + A TP P PP+P + P AP S+ T P P A
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368
Score = 32.3 bits (72), Expect = 1.3
Identities = 38/122 (31%), Positives = 45/122 (36%), Gaps = 14/122 (11%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP-GMFPLWPPMGPFPPVPPPPSSGE 402
P P A +G P AP P P P + GL + G P G P P P +SG
Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 1002
Query: 403 AVAPPSTSAALSR----------PSGA--ATTTAAGTSATAASATASGPGSGSAPEAGPA 450
A + + A SR P GA A+ S T A A G GS G A
Sbjct: 1003 KAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 1062
Query: 451 PG 452
G
Sbjct: 1063 EG 1064
>gi|21314654 ring finger protein 139 [Homo sapiens]
Length = 664
Score = 73.2 bits (178), Expect = 7e-13
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 18/203 (8%)
Query: 141 IVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQ 200
+ + +F+L +L + H H L F E + + + LT+ Y L +D
Sbjct: 395 VSACLFILPVLLSYVLWH--HYALNTWLFAVTAFCVELCLKVIVSLTV---YTLFMIDGY 449
Query: 201 SENPWDNKAVYMLYTELFTGFIKVLLYMAFM------TIMI----KVHTFPLFAIRPMYL 250
W+ Y+ Y TG I ++ M T+M K+ F + + +
Sbjct: 450 YNVLWEKLDDYVYYVRS-TGSIIEFIFGVVMFGNGAYTMMFESGSKIRAF-MMCLHAYFN 507
Query: 251 AMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHI 310
Q K + R A++ +N+L P+ LQ +++VC IC E T A+ PCNH
Sbjct: 508 IYLQAKNGWKTFMNRRTAVKKINSL-PEIKGSRLQEINDVCAICYHEFTTSARITPCNHY 566
Query: 311 FHTSCLRSWFQRQQTCPTCRMDV 333
FH CLR W Q TCP C V
Sbjct: 567 FHALCLRKWLYIQDTCPMCHQKV 589
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 73.2 bits (178), Expect = 7e-13
Identities = 58/156 (37%), Positives = 66/156 (42%), Gaps = 20/156 (12%)
Query: 339 PAQSPPPPEPADQGPPPAPH-----PPPLLPQPPNFPQGLLPPFP---PGMFPLWPPMGP 390
P QS P P PPP PH PPP P P P PP P P PP
Sbjct: 51 PGQSGPKPPI----PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS 106
Query: 391 FPPV---PPPPSSGEAVAPPSTSA---ALSRPSGAATTTAAGTSATAASATASGPGSGSA 444
PV P P+ G APP++S+ A SGA + G + T A S P G+
Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP-PGAP 165
Query: 445 PEAGPAPGFPFPPPWMGMPLPPPFAFP-PMPVPPAG 479
P P+ G P PP G P PPP A P P P P G
Sbjct: 166 PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201
Score = 67.8 bits (164), Expect = 3e-11
Identities = 54/161 (33%), Positives = 70/161 (43%), Gaps = 24/161 (14%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS 400
+ P P P GP P P PPP PP+ Q PP P P PP PP P P
Sbjct: 44 RGPMGPGPGQSGPKP-PIPPP----PPHQQQQQPPPQQPP--PQQPPPHQPPPHPQPHQQ 96
Query: 401 GEAVAPPSTSA--ALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA-------- 450
+ PP S+ +++ G A + A++++ A+ P SG+ P +GP
Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPA 156
Query: 451 -----PGFPFP-PPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
PG P P PP G+P PP A P P PPA G P
Sbjct: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGGP-PPPPAAVPGPGP 196
Score = 64.3 bits (155), Expect = 3e-10
Identities = 54/173 (31%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 322 RQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM 381
+QQ P + + P Q PP P+P Q PP PPP P QG P PG+
Sbjct: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP---PPPQDSSKPVVAQG--PGPAPGV 121
Query: 382 FPLWPPMGPFPPVPP-----PPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATA 436
P PP P PP SG P A S P GA T + A
Sbjct: 122 GSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQA 181
Query: 437 SG--------PGSGSAPEAGPAPGFP-------FPPPWMGMPLPPPFAFPPMP 474
G PG G P+ GP PG P P P G L P P P
Sbjct: 182 GGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
Score = 60.5 bits (145), Expect = 5e-09
Identities = 54/173 (31%), Positives = 58/173 (33%), Gaps = 26/173 (15%)
Query: 341 QSPPPPEPAD-----QGPPPAPH----PPPLLPQPPNFP--QGLLPPFPPGMFPLWPPM- 388
Q PPPP+ + QGP PAP PP PP P G P PG P PP
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157
Query: 389 ---GPFPPVPPPPSSGEAVAPPSTSAALSRPS-----GAATTTAAGTSATAASATASGPG 440
P P P PPSSG PP P+ G G GP
Sbjct: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217
Query: 441 SGSAPEAGPAPGFPFPP------PWMGMPLPPPFAFPPMPVPPAGFAGLTPEE 487
G P G P PP P G PP+ PP G G EE
Sbjct: 218 PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEE 270
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/134 (32%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Query: 331 MDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGL-LPPFPPGMFPLWPPMG 389
++ ++ L Q+PPPP P+ GPPP P PP PP +G PP PP P
Sbjct: 265 VEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP------ 318
Query: 390 PFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGP 449
P PPPPS PP + P A ++A + + G G + P P
Sbjct: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
Query: 450 APGFPFPPPWMGMP 463
P P PPP G+P
Sbjct: 379 PPPPPGPPPPPGLP 392
Score = 53.5 bits (127), Expect = 6e-07
Identities = 41/120 (34%), Positives = 46/120 (38%), Gaps = 33/120 (27%)
Query: 343 PPPPEPADQGPPP-------APHPPPLL-------PQPPNFPQGLLPPFPPG-MFPLWPP 387
PPPP P + GPPP AP PPP P PP+ P +PP PP M+P PP
Sbjct: 289 PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPP 348
Query: 388 M-------GPFPP-----------VPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSA 429
GP PP PPPP PP S TTA +A
Sbjct: 349 ALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAA 408
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 72.4 bits (176), Expect = 1e-12
Identities = 50/153 (32%), Positives = 58/153 (37%), Gaps = 16/153 (10%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 69 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAAT------TTAAGTSATAASATASGPGSGSAPE 446
P PPP G+ PP ++P G G + + +S + G G P+
Sbjct: 129 PQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Query: 447 AGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
G P P PPP PP P PP G
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Score = 72.4 bits (176), Expect = 1e-12
Identities = 51/154 (33%), Positives = 58/154 (37%), Gaps = 17/154 (11%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP---------FPPGMFPLWPPMGPF 391
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 392 PPVPPPPSSGEAVAPPSTSAALSRPSGAAT------TTAAGTSATAASATASGPGSGSAP 445
P PPP G+ PP ++P G G S + +S + G G P
Sbjct: 252 QPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309
Query: 446 EAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
+ G P P PPP PP P PP G
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Score = 62.8 bits (151), Expect = 9e-10
Identities = 49/156 (31%), Positives = 58/156 (37%), Gaps = 21/156 (13%)
Query: 341 QSPPPPEPADQGPPP-------APHPPPLLPQPPNFPQG----LLPPFPPGMFPLWPPMG 389
Q PPPP QGPPP P PP PP PQG PPG PP G
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--PQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 390 PFPPVPPPPSSGEAVAPPSTSAALSRPSGAAT------TTAAGTSATAASATASGPGSGS 443
P PPP G+ PP ++P G G + + ++ + G G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 444 APEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
P+ G P P PPP PP P PP G
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Score = 60.1 bits (144), Expect = 6e-09
Identities = 49/155 (31%), Positives = 55/155 (35%), Gaps = 19/155 (12%)
Query: 341 QSPPPPEPADQGPPP-APHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPS 399
Q PP P QGPPP + P P PP PQG PP G P PP P P PPP
Sbjct: 48 QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQGPPP-PGKPQGPPPQ 104
Query: 400 SGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPW 459
++ +P S P G P G+ P+ P PG P PP
Sbjct: 105 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164
Query: 460 MG--------MPLPPPFAFPPM-------PVPPAG 479
G P P PP P PP G
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 199
Score = 59.3 bits (142), Expect = 1e-08
Identities = 56/175 (32%), Positives = 62/175 (35%), Gaps = 39/175 (22%)
Query: 341 QSPPPPEPADQGPPP------APHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPPMG 389
Q PPPP QGPPP +P PP PQ P N PQG PP PPG PP G
Sbjct: 90 QGPPPPGKP-QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQG 146
Query: 390 PFPPVPPPPSSGEAVAPP-------STSAALSRPSGAAT---TTAAGTSATAASATASGP 439
P PPP PP S+ + +P G G P
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 440 GSGSAPEAGPAPGFPFPPPWMG--------MPLPPPFAFPPM-------PVPPAG 479
G+ P+ P PG P PP G P P PP P PP G
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG 261
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/163 (30%), Positives = 53/163 (32%), Gaps = 55/163 (33%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP---------FPPGMFPLWPPMGPF 391
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 392 PPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP 451
P PPP G+ PP P G+ P+ P P
Sbjct: 314 QPQGPPPPPGKPQGPP-------------------------------PQGGNKPQGPPPP 342
Query: 452 GFPFPPPWM------------GMPLPPPFA---FPPMPVPPAG 479
G P PP G P PP P P PPAG
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385
Score = 58.2 bits (139), Expect = 2e-08
Identities = 51/145 (35%), Positives = 59/145 (40%), Gaps = 22/145 (15%)
Query: 341 QSPPPPEPADQGPPP-------APHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPPM 388
Q PPPP QGPPP + PP PQ P N PQG PP PPG PP
Sbjct: 275 QGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQ 331
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGP----GSGSA 444
G P PPP G+ PP + SR + + G + P G+
Sbjct: 332 GGNKPQGPPP-PGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 390
Query: 445 PEAGPA--PGFPFPPPWMGMPLPPP 467
P+A PA P P PP G P PP
Sbjct: 391 PQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 57.0 bits (136), Expect = 5e-08
Identities = 49/147 (33%), Positives = 55/147 (37%), Gaps = 21/147 (14%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPP-LLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
L A P +PP QGPP P P PQ N PQG PP PPG PP G
Sbjct: 31 LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNK 88
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPG 452
P PPP G+ PP P G + + + G G P+ G P
Sbjct: 89 PQGPPP-PGKPQGPP--------PQG---------DKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 453 FPFPPPWMGMPLPPPFAFPPMPVPPAG 479
P PPP PP P PP G
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPG 157
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/180 (32%), Positives = 67/180 (37%), Gaps = 40/180 (22%)
Query: 337 SLPAQSPP--PPEPADQG--PPPAPHPPPLLPQPP-----NFPQGLLPP----------- 376
S A+SPP P P QG P P PPP PQ P N PQG PP
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 377 -------FPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAAT------TT 423
PPG PP G P PPP G+ PP ++P G
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPP 349
Query: 424 AAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPP--PFAFPPM--PVPPAG 479
G S + ++ + G G + G P P PPP G P P P A P P PP G
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGP-PPPAGGNPQQPQAPPAGQPQGPPRPPQG 408
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/131 (29%), Positives = 45/131 (34%), Gaps = 33/131 (25%)
Query: 356 APHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSR 415
A +P PQ N PQG PP PPG PP G P PPP G+ PP
Sbjct: 33 AGNPQGAPPQGGNKPQG--PPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-------- 82
Query: 416 PSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPV 475
P G+ P+ P PG P PP G P + P P
Sbjct: 83 -----------------------PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 119
Query: 476 PPAGFAGLTPE 486
P G P+
Sbjct: 120 GPPPQGGNQPQ 130
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 71.2 bits (173), Expect = 3e-12
Identities = 49/150 (32%), Positives = 55/150 (36%), Gaps = 11/150 (7%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 393 PVPPPPSSGEAVAPPSTSAALSR---PSGAATTTAAGTSATAASATASGPGSGSAPEAGP 449
P PPP G+ PP + P G + +S + G G P+ G
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
Query: 450 APGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
P P PPP PP P PP G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258
Score = 69.7 bits (169), Expect = 7e-12
Identities = 51/152 (33%), Positives = 56/152 (36%), Gaps = 15/152 (9%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG--------LLPPFPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSG---AATTTAAGTSATAASATASGPG--SGSAPEA 447
P PPP G+ PP +RP G + + S PG G P+
Sbjct: 108 PQGPPPPPGKPQGPPPQGG--NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
G P P PPP PP P PP G
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/157 (34%), Positives = 62/157 (39%), Gaps = 21/157 (13%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP--------FPPGMFPLWPPMGPFP 392
Q PPPP QGPPP P P PP PQG P PPG PP G
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAAT------TTAAGTSATAASATASGPGSGSAPE 446
P PPP G+ PP ++P G A G S + ++ + G G +
Sbjct: 230 PQGPPPPPGKPQGPPPQGG--NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ 287
Query: 447 AGPAPGFPFPPPWMGMPLPP--PFAFPPM--PVPPAG 479
G P P PPP G P P P A P P PP G
Sbjct: 288 EGNNPQGP-PPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
Score = 61.6 bits (148), Expect = 2e-09
Identities = 76/300 (25%), Positives = 93/300 (31%), Gaps = 85/300 (28%)
Query: 341 QSPPPPEPADQGPPP------APHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPPMG 389
Q PPPP QGPPP +P PP PQ P N PQG PP PPG PP G
Sbjct: 69 QGPPPPGKP-QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQG 125
Query: 390 ---------PFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPG 440
P P PPP ++ +P S P G P
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185
Query: 441 SGSAPEAGPAPGFPFPPPWMG-------MPLPPPFAFPPM-------PVPPAGFAGLTPE 486
G P+ P PG P PP G P P PP P PP G P+
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG----KPQ 241
Query: 487 ELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETA 546
G++ Q GPP P +
Sbjct: 242 GPPPQGGNKPQ---------------------------------GPPPPGKPQGPPAQGG 268
Query: 547 TTVVAAASSTSIP---------SSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEP 597
+ +A S P + + P G +P P + PPA + G P+ G P
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP--QAPPAGQPQGPPRPPQGGRP 326
Score = 47.0 bits (110), Expect = 5e-05
Identities = 51/141 (36%), Positives = 55/141 (39%), Gaps = 29/141 (20%)
Query: 337 SLPAQSPP--PPEPADQG--PPPAPHPPPLLPQPP-----NFPQGLLPPFPPGMFPLWPP 387
S +QSPP P P QG P P PPP PQ P N PQG P PPG P
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG---PPPPG-----KP 260
Query: 388 MGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASG-PGSGSAPE 446
G PP S A +PP +P G G + A G P AP
Sbjct: 261 QG--PPAQGGSKSQSARSPP------GKPQG--PPQQEGNNPQGPPPPAGGNPQQPQAPP 310
Query: 447 AGPAPGFPFPPPWMGMPLPPP 467
AG G P PP G P PP
Sbjct: 311 AGQPQGPPRPPQG-GRPSRPP 330
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 70.5 bits (171), Expect = 4e-12
Identities = 83/311 (26%), Positives = 102/311 (32%), Gaps = 65/311 (20%)
Query: 340 AQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQG-LLPPFPPGMFPLWPPMGPFPPVPPPP 398
A+ PPPP PPAP PPP LP P P L PP PP P+ PP P PP PP
Sbjct: 399 AKLPPPPLT-----PPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSPPPLPSPPPPPAQ 450
Query: 399 SSGEAVAPPSTSAALSRPSGAATTTA----------AGTSATAASATASGPGSGSAPEAG 448
E PP A SR G T AG T+ +G PE
Sbjct: 451 EEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510
Query: 449 PAPG-------------------------FPFPPPWMGM--PLPPPFAFPPMPVPPAGFA 481
P P +M P PP P+ PP +
Sbjct: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS 570
Query: 482 GLTPEELRALEGHERQHLEARL-----QSLRNIHTLLDAAMLQINQYLTVLASLGPPRPA 536
P+E + R + R+I + + L PP PA
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630
Query: 537 TSVNSTEETATTVVAAASSTSIPSSEA--------TTPTPGASPPAPEMERPPAPESVGT 588
S T++ + SEA TP P +P APE E PPA +S
Sbjct: 631 PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS--- 687
Query: 589 EEMPEDGEPDA 599
P + EP A
Sbjct: 688 ---PAEPEPRA 695
Score = 56.6 bits (135), Expect = 7e-08
Identities = 76/282 (26%), Positives = 102/282 (36%), Gaps = 60/282 (21%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPP---PLLPQPPNF--PQGLLPPFPPGM 381
PT R L LP P PP P PPPAP PLL + P F + L + +
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
Query: 382 FPLWPPMG-PFPPVPPPPSSGEAVAPPSTSAA-----LSRPSGAATTTA---AGTSATAA 432
P PP+G P P P PP + ++ A P A LS P A T A S A
Sbjct: 667 TP--PPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGA 724
Query: 433 SATASGPGSGS-------------APEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
A ++GP + + P+A P P PP P P PP+ A
Sbjct: 725 PALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP------PSPQQMPPL--EKAR 776
Query: 480 FAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQI-----NQYLTVLASLGPPR 534
AG+ L +E + +LL A +Q+ Q V AS+
Sbjct: 777 IAGVGSLPLSGVE--------------EKMFSLLKRAKVQLFKIDQQQQQKVAASM---- 818
Query: 535 PATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPE 576
P + EE A V + + S + + P PE
Sbjct: 819 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPE 860
Score = 47.0 bits (110), Expect = 5e-05
Identities = 81/313 (25%), Positives = 112/313 (35%), Gaps = 42/313 (13%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQP-PNFPQGLL--PPFP-PGMFPLWPPM 388
VLR + P P EPA PP PP P P P + +L P F + PP
Sbjct: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P PP PP PS A A S L R + T + A + T G+ APE
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLR-APQFTPSEAHLKIYESVLTPPPLGAPEAPEPE 680
Query: 449 PAPGFPFP----PPWMG----MPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLE 500
P P P P +G + LP F P+ P A ++P AL + +
Sbjct: 681 PPPADDSPAEPEPRAVGRTNHLSLP---RFAPVVTTPVK-AEVSPHGAPALSNGPQTQAQ 736
Query: 501 ARLQSLRNIHT-LLDAAMLQINQYLTVLASLGPPRP---------------ATSVNSTEE 544
LQ L+ + T LL A+ L PP P + ++ EE
Sbjct: 737 L-LQPLQALQTQLLPQALPPPQPQLQ-----PPPSPQQMPPLEKARIAGVGSLPLSGVEE 790
Query: 545 TATTVVAAASSTSIPSSEATTPTPGAS---PPAPEMERPPAPESVGTEEMPEDGEPDAAE 601
+++ A + AS P +ME ++ P E ++ E
Sbjct: 791 KMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVE 850
Query: 602 LRRRRLQKLESPV 614
+R R ESPV
Sbjct: 851 AKRERPSGPESPV 863
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 13/149 (8%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPV 394
R+ P+ P P P+ PP P L PP ++ P L PP GP P
Sbjct: 1912 RSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPT---SVVTALTPTSGELAPP-GPAPSP 1967
Query: 395 PPPPSSGEAVAPPSTSAALSRPSGAATTTAAGT--------SATAASATASGPGSGSAPE 446
PPP G + LS + GT +A A ++ GPG S E
Sbjct: 1968 PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEE 2027
Query: 447 AGPAPGF-PFPPPWMGMPLPPPFAFPPMP 474
+ P + FP + P P A P P
Sbjct: 2028 SSPTSRYIHFPVTVVSAPGLAPSATPGAP 2056
Score = 45.1 bits (105), Expect = 2e-04
Identities = 69/315 (21%), Positives = 95/315 (30%), Gaps = 88/315 (27%)
Query: 332 DVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLL----------------- 374
+ RA SPP P P+ P P + P+ F + +
Sbjct: 483 EAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT 542
Query: 375 --------PPFPPGMFP---LWPPMGPFPPVP----PPPSSGEAVAPPSTSAAL--SRPS 417
PP PP + L PP+ PPVP P PS A PPST L R S
Sbjct: 543 PRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602
Query: 418 GAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPP------------------- 458
T TS T P A P P P PPP
Sbjct: 603 ILREPTFRWTSLTRELPPP--------PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTP 654
Query: 459 -------WMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHT 511
+ + PPP P P P A +P E HL R
Sbjct: 655 SEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLP----RFAPV 710
Query: 512 LLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGAS 571
+ +++ + S GP A + + T ++ A
Sbjct: 711 VTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQA----------------LP 754
Query: 572 PPAPEMERPPAPESV 586
PP P+++ PP+P+ +
Sbjct: 755 PPQPQLQPPPSPQQM 769
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/180 (27%), Positives = 66/180 (36%), Gaps = 34/180 (18%)
Query: 317 RSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPP----PAPHPPPLLPQPPNFPQG 372
R W++ CR+ R P + P E A++ PAP P + P
Sbjct: 1773 RCWYR-------CRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTD 1825
Query: 373 LLPPFPPGMF--------PLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTA 424
+L P P PL P G PP P SG + P+ S + RP G +
Sbjct: 1826 VLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPS-RRPLGGVSFGP 1884
Query: 425 AGTSATAASATASGPGSGSAPEAGPAPGFPFPP-----PWMGMPLPPP--FAFPPMPVPP 477
+ + +S T P G P FP PP P P PPP +A PP+ P
Sbjct: 1885 LPSPGSPSSLTHHIPTVGD-------PDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSP 1937
Score = 37.7 bits (86), Expect = 0.031
Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 13/86 (15%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP-PGMFPLWPPMGPFPPVPP 396
+ + P P P Q P P PP + P P LPP P G+ P+ + P PP PP
Sbjct: 2204 MAGEGEPVPPPVKQ-P---PLPPTISPTAPT--SWTLPPGPLLGVLPVVGVVRPAPPPPP 2257
Query: 397 PP-----SSGEAVAPPSTSAALSRPS 417
PP SSG A +PP + + R S
Sbjct: 2258 PPLTLVLSSGPA-SPPRQAIRVKRVS 2282
Score = 34.7 bits (78), Expect = 0.27
Identities = 40/126 (31%), Positives = 44/126 (34%), Gaps = 21/126 (16%)
Query: 335 RASLPAQSPP--PPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP 392
R +P SP P GP P+P P L + P P FP P P P
Sbjct: 1864 RIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTH--HIPTVGDPDFPA---PPRRSRRPSP 1918
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPG 452
P PP S A P TS L P + TA P SG GPAP
Sbjct: 1919 LAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALT------------PTSGELAPPGPAP- 1965
Query: 453 FPFPPP 458
PPP
Sbjct: 1966 -SPPPP 1970
Score = 31.6 bits (70), Expect = 2.3
Identities = 39/142 (27%), Positives = 50/142 (35%), Gaps = 20/142 (14%)
Query: 463 PLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQ 522
PLPPP P PP TP R EG ER ++A + LR A + +
Sbjct: 160 PLPPPRLADVAPTPPK-----TPARKRGEEGTERM-VQALTELLRRAQA-PQAPRSRACE 212
Query: 523 YLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPA 582
T S G P P VV A ++ +IP E PP P + P
Sbjct: 213 PSTPRRSRGRP-PGRPAGPCRRKQQAVVVAEAAVTIPKPE---------PPPPVV---PV 259
Query: 583 PESVGTEEMPEDGEPDAAELRR 604
G+ + E P RR
Sbjct: 260 KHQTGSWKCKEGPGPGPGTPRR 281
Score = 30.0 bits (66), Expect = 6.6
Identities = 33/123 (26%), Positives = 40/123 (32%), Gaps = 18/123 (14%)
Query: 379 PGMFPLWPPMGPFPPVPP-----PPSSGEAVAPPSTSAALSRPSGAATTTAAGTS----- 428
PG P PP PP PS G +P + + GA
Sbjct: 2124 PGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEP 2183
Query: 429 ---ATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPP---PFAFPPMPVPPAGFAG 482
AT+ + G AG G P PPP PLPP P A +PP G
Sbjct: 2184 PKPATSKIILVNKLGQVFVKMAGE--GEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLG 2241
Query: 483 LTP 485
+ P
Sbjct: 2242 VLP 2244
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 70.5 bits (171), Expect = 4e-12
Identities = 62/169 (36%), Positives = 72/169 (42%), Gaps = 31/169 (18%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLL-----PQPPNFPQGLLPPFPPGMFPL--WPPMGPFPP 393
+ PP P GPP PPP L P+PP P+ L PP PPG PL PP GP P
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPP-LPESLPPP-PPGGLPLPPMPPTGPAPS 272
Query: 394 VP------PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPG-----SG 442
P PPP+ G V PP + + P+ A G A PG SG
Sbjct: 273 GPPGPPQLPPPAPG--VHPP--APVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG 328
Query: 443 SAPEA----GPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPE 486
P A PAPG PP G+ P P PP P V P AG+ P+
Sbjct: 329 VHPPAPGVHPPAPG--VHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQ 375
Score = 55.5 bits (132), Expect = 1e-07
Identities = 52/159 (32%), Positives = 62/159 (38%), Gaps = 17/159 (10%)
Query: 338 LPAQSPPPPEPADQG-------PPPAP--HPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388
LP PP PA G PPPAP HPP + PP G+ PP PG+ P P +
Sbjct: 259 LPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPP--ASGVHPP-APGVHPPAPGV 315
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P P PP+SG V PP + + P+ A G A PG P AG
Sbjct: 316 HPPAPGVHPPTSG--VHPP--APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAG 371
Query: 449 PAPGFPFPPPWMGMPLP-PPFAFPPMPVPPAGFAGLTPE 486
P P P P P PP P G+ P+
Sbjct: 372 VHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ 410
Score = 40.8 bits (94), Expect = 0.004
Identities = 39/133 (29%), Positives = 46/133 (34%), Gaps = 8/133 (6%)
Query: 339 PAQSPPPP---EPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
P PP P PA PPAP P P P + P PG+ P P + P P
Sbjct: 334 PGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGV 393
Query: 396 PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPF 455
PP+ G P +P G +A G S PG P P
Sbjct: 394 HPPAPG---MHPQAPGVHPQPPG-VHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPL 449
Query: 456 PPPWMG-MPLPPP 467
P G +P PPP
Sbjct: 450 PSEGPGNIPPPPP 462
Score = 40.0 bits (92), Expect = 0.006
Identities = 28/74 (37%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 339 PAQSPPPPEPADQGP-----PPAPHP--PPLLPQPPNFPQ---GLLPP--FPPGMFPLWP 386
P PP P Q P PP HP P + PQPP G+ PP PP + P P
Sbjct: 391 PGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLP 450
Query: 387 PMGPFPPVPPPPSS 400
GP PPPP++
Sbjct: 451 SEGPGNIPPPPPTN 464
Score = 35.4 bits (80), Expect = 0.16
Identities = 41/163 (25%), Positives = 47/163 (28%), Gaps = 64/163 (39%)
Query: 439 PGSGSAPEAGPAPGFPFPPPWM------------GMPLPPPFAFPPMPVPPAGFAGLTPE 486
P S P AGP PG PPP + +P PPP P P+PP G A P
Sbjct: 218 PAPPSLP-AGP-PGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPP 275
Query: 487 ELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETA 546
GPP+ A
Sbjct: 276 --------------------------------------------GPPQLPPPAPGVHPPA 291
Query: 547 TTVVAAASSTSIPSSEATTPTPGASPPAPEME------RPPAP 583
V AS P+ P PG PPAP + PPAP
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAP 334
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 69.3 bits (168), Expect = 1e-11
Identities = 52/150 (34%), Positives = 64/150 (42%), Gaps = 20/150 (13%)
Query: 343 PPPPEPADQGPPPAPH-PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSG 401
PPP P Q PPP P PPP+LP P+ P ++PP P P PP PPP
Sbjct: 517 PPPFVPYSQMPPPLPTMPPPVLP--PSLPPPVMPPALPATVP--------PPGMPPP--- 563
Query: 402 EAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMG 461
V PPS ++ P + ++AG + S G P P P P
Sbjct: 564 --VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAG---PPPVLPPPSLSSTAPPPV 618
Query: 462 MPLPP-PFAFPPMPVPPAGFAGLTPEELRA 490
MPLPP A PP +PP G P +L A
Sbjct: 619 MPLPPLSSATPPPGIPPPGVPQGIPPQLTA 648
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/163 (33%), Positives = 67/163 (41%), Gaps = 26/163 (15%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWP 386
PT VL SLP PP PA PP P PP++P P+ P + PPGM P
Sbjct: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMP--PPVMP--PSLPTSVP---PPGMPPSLS 583
Query: 387 PMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPE 446
GP PPV PPPS A PP L PS S+TA P P
Sbjct: 584 SAGP-PPVLPPPSLSSAGPPP----VLPPPS--------------LSSTAPPPVMPLPPL 624
Query: 447 AGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELR 489
+ P PPP + +PP P+P + + PE+ R
Sbjct: 625 SSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
Score = 62.0 bits (149), Expect = 2e-09
Identities = 88/357 (24%), Positives = 128/357 (35%), Gaps = 73/357 (20%)
Query: 309 HIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPA---------PHP 359
H+ L+ Q+Q C VL+ P PPPP P PPP P
Sbjct: 57 HLAQLQQLQQMHQKQMQC------VLQ---PHHLPPPPLP----PPPVMPGGGYGDWQPP 103
Query: 360 PPLLPQPP---------------------NFPQGLL----------PPFPPGMF-----P 383
PP +P PP + P GL+ PP PPG +
Sbjct: 104 PPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQS 163
Query: 384 LWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGA-ATTTAAGTSATAASATASGPGSG 442
PP P P PP SS + P S + S PS + T + +S++++S +
Sbjct: 164 YMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQS 223
Query: 443 SAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEAR 502
P + +P P L P PP PP + E L + G + + E +
Sbjct: 224 YLPSSQASPSRPSQGHSKSQLLAP----PPPSAPPGNKTTVQQEPLES--GAKNKSTEQQ 277
Query: 503 LQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSE 562
+ + + Q Y L SL + T V+ VVA + + E
Sbjct: 278 QAAPEPDPSTMTPQEQQQYWYRQHLLSL---QQRTKVHLPGHKKGPVVAKDTPEPV-KEE 333
Query: 563 ATTPTPGASPPAPEMERPPAP---ESVGTEEMPEDGEPDAAELRRRRLQKLESPVAH 616
T P P +P E PP P E V PE+ + + E RL++L++ AH
Sbjct: 334 VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPE-EDARLKQLQAAAAH 389
Score = 53.9 bits (128), Expect = 4e-07
Identities = 49/149 (32%), Positives = 59/149 (39%), Gaps = 21/149 (14%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
+S P PPP + + PPP PP + +P P P P+ PP P PP+P
Sbjct: 1500 SSRPGMYPPPG--SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPI-PPPPPPPPLP 1556
Query: 396 PPPSSGEAVAPPSTSAALSRPSGA-------ATTTAAGTSATAASATASGPGSGSAPEAG 448
PPP V P TSA T G ++ S TA+ P SAP
Sbjct: 1557 PPP----PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIP---SAPVLP 1609
Query: 449 PAPGFPFPPPWMGMPLPPPFAFPPMPVPP 477
P P PP P P P PPM PP
Sbjct: 1610 PPPVHSSIPP----PGPVPMGMPPMSKPP 1634
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 33/167 (19%)
Query: 334 LRASLPAQSPPPPEPADQGPPP--------APHPPPLLPQPP----NFPQGLLPPFPPGM 381
L ++ P PPP + GPPP + PPP++P PP P G+ PP P
Sbjct: 582 LSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQG 641
Query: 382 FPLWPPMGPFPP-----------------VPPPPSSGEA----VAPPSTSAALSRPSGAA 420
P P PP +P P S G A PP SA S +
Sbjct: 642 IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSK 701
Query: 421 TTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPP 467
+ ++ ++ G G SA + P P G LP P
Sbjct: 702 APLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDP 748
Score = 39.3 bits (90), Expect = 0.011
Identities = 54/229 (23%), Positives = 71/229 (31%), Gaps = 83/229 (36%)
Query: 380 GMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASG 438
G + PP P+ +PPP P+ V PPS + P+ AT
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATV---------------- 555
Query: 439 PGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQH 498
P G P P P P P GMP A PP +PP
Sbjct: 556 PPPGMPPPVMP-PSLPTSVPPPGMPPSLSSAGPPPVLPPPS------------------- 595
Query: 499 LEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR--PATSVNSTEETATTVVAAASST 556
L+S GPP P S++ST A
Sbjct: 596 ----------------------------LSSAGPPPVLPPPSLSST--------APPPVM 619
Query: 557 SIPSSEATTPTPGASPPA------PEMERPPAP--ESVGTEEMPEDGEP 597
+P + TP PG PP P++ P P S + ++PE P
Sbjct: 620 PLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/122 (31%), Positives = 47/122 (38%), Gaps = 36/122 (29%)
Query: 381 MFPLWPPMG-----PFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASAT 435
M+P W G P PPVPPPP VA P S P +++TT A S++ +
Sbjct: 1 MYPNWGRYGGSSHYPPPPVPPPP----PVALPEASPG---PGYSSSTTPAAPSSSGFMSF 53
Query: 436 ASGPGSG---------------SAPEAGPAPGFPFPPPWM-----GMPLPPPFAFPPMPV 475
+ P P P P PPP M G PPP PPMP
Sbjct: 54 REQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLP-PPPVMPGGGYGDWQPPP---PPMPP 109
Query: 476 PP 477
PP
Sbjct: 110 PP 111
Score = 31.6 bits (70), Expect = 2.3
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 13/50 (26%)
Query: 441 SGSAPEAGPAPGFPFPPPWMGMP--------LPP-----PFAFPPMPVPP 477
+ S P P PG PPP MG P PP P PP+P+PP
Sbjct: 1499 TSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
Score = 30.0 bits (66), Expect = 6.6
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 5/67 (7%)
Query: 455 FPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP--EELRALEGHERQHLEARLQSLRNIHTL 512
+PPP +P PPP A P P + TP QHL A+LQ L+ +H
Sbjct: 14 YPPP--PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHL-AQLQQLQQMHQK 70
Query: 513 LDAAMLQ 519
+LQ
Sbjct: 71 QMQCVLQ 77
>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
sapiens]
Length = 245
Score = 68.9 bits (167), Expect = 1e-11
Identities = 57/169 (33%), Positives = 68/169 (40%), Gaps = 21/169 (12%)
Query: 337 SLPAQSPPPPEPADQGPPPAPHPP--PLLPQP----PNFPQGLLPPFPPGMFP-----LW 385
S P +P P G PP+ P P P P P+ P PP PP FP
Sbjct: 37 SNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCP 96
Query: 386 PPMGPF--PPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGS 443
PP GP+ P VP P +G P L RP GA T AA + +SGP +
Sbjct: 97 PPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPG 156
Query: 444 APEAGPAPGFPFPPPWMGMPLPP----PFAFPPMP---VPPAGFAGLTP 485
P P P+P P P PP P A PP+P VPP + P
Sbjct: 157 MGGQYPTPNMPYPSPG-PYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAP 204
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/170 (30%), Positives = 61/170 (35%), Gaps = 45/170 (26%)
Query: 337 SLPAQSPPPPEPADQGP-PPAPHPPPLLPQP--------PNFPQGLLP----------PF 377
S P P P P GP P P+P P +P P P P P P+
Sbjct: 94 SCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPW 153
Query: 378 PPGM---FPL----WPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSAT 430
PGM +P +P GP+P PPP + G APP P G A G A
Sbjct: 154 APGMGGQYPTPNMPYPSPGPYPAPPPPQAPG--AAPPV-------PWGTVPPGAWGPPAP 204
Query: 431 AASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGF 480
+ T S P P P P PF P P PPMP P +
Sbjct: 205 YPAPTGSYP----TPGLYPTPSNPFQVP------SGPSGAPPMPGGPHSY 244
Score = 32.0 bits (71), Expect = 1.7
Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 405 APPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGM-P 463
+P TSA + G G++ + S SG P A P+ PF P GM P
Sbjct: 15 SPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPST-VPFGPAPTGMYP 73
Query: 464 LPPPFA---FPPMPVPPAG 479
PP PP P PP+G
Sbjct: 74 SVPPTGPPPGPPAPFPPSG 92
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.2 bits (165), Expect = 2e-11
Identities = 70/256 (27%), Positives = 93/256 (36%), Gaps = 21/256 (8%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAPPSTSAALSR--PSGAAT--TTAAGTSATAASATASGPGSGSAPEA 447
P PPP + AP S +R P G T + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 567
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 568 PGASPPAPEMERPPAP 583
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/130 (33%), Positives = 52/130 (40%), Gaps = 22/130 (16%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 457
P EA++PP T ++ S P+ A A A P PAP P P
Sbjct: 191 PPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP--------PPPVPAPAPPAPASP 242
Query: 458 PWMGMPLPPP 467
+G L PP
Sbjct: 243 HTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/217 (25%), Positives = 62/217 (28%), Gaps = 81/217 (37%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLW----------------- 385
PP P A PPP P P P P P + FPPG W
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275
Query: 386 PPMGPFPP--------------------VPPPPSSGEAVAPPSTSAALSRPSGAATTTAA 425
PP P P VPPP + P + R AT A
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 426 GT-----------------------------SATAASATASGPGSGSAPEAG--PAPGFP 454
ATA ++ G A E P P P
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 455 FPPPWMGMPLPPPF-----AFPPMPV------PPAGF 480
PPP PLPPP A PP+P PPAGF
Sbjct: 396 LPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 15/118 (12%)
Query: 304 RLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLL 363
RLP FH + + P C + L+A+ PA SP + Q A PPP
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGE-LKATAPA-SPRLGQSQSQADERAGTPPPA- 393
Query: 364 PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAALSRPSGAA 420
PP PP PL PP P PP PP P + +A PP+ + S A
Sbjct: 394 -----------PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA 440
Score = 43.5 bits (101), Expect = 6e-04
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP-----FPPGMFPLWPPMG 389
RA P +PP P PA PPPAP PP P P + PP P P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP-- 443
Query: 390 PFPPVPPPPSSGEAVAP 406
P PP P + + AP
Sbjct: 444 --KPNPPSPENTASSAP 458
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/121 (33%), Positives = 48/121 (39%), Gaps = 18/121 (14%)
Query: 365 QPPNFPQGLL-PPFPPGMFP------LWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPS 417
+P + Q LL PP PPG P PP G P+P PPS+ A PP P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG--SPLPSPPST--APPPPPLLLEPPPPP 184
Query: 418 GAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPP 477
A A + T S P + P+ P P PP P PPP P P PP
Sbjct: 185 SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP----PAPPLAFLAPPPPPV---PAPAPP 237
Query: 478 A 478
A
Sbjct: 238 A 238
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 528 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 584
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 585 SVGTEEMPEDGEPDAA 600
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
Score = 32.0 bits (71), Expect = 1.7
Identities = 45/151 (29%), Positives = 54/151 (35%), Gaps = 25/151 (16%)
Query: 354 PPAPHPPP----LLPQPPNFPQGLL-PPFPPGMFP--LWPPMGPF-PPVPPPPSSGEAVA 405
P A + PP LLP P+ +L P PP P PP P PP + G A
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
Query: 406 PPSTSA------ALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPGFPFPPP 458
+TS A S P+ A+T T T+ + A SGP A P
Sbjct: 673 LKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQAR 732
Query: 459 WMGMP-----LP-----PPFAFPPMPVPPAG 479
G P LP AFPP P G
Sbjct: 733 GEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 68.2 bits (165), Expect = 2e-11
Identities = 70/256 (27%), Positives = 93/256 (36%), Gaps = 21/256 (8%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAPPSTSAALSR--PSGAAT--TTAAGTSATAASATASGPGSGSAPEA 447
P PPP + AP S +R P G T + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 567
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 568 PGASPPAPEMERPPAP 583
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/130 (33%), Positives = 52/130 (40%), Gaps = 22/130 (16%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 457
P EA++PP T ++ S P+ A A A P PAP P P
Sbjct: 191 PPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP--------PPPVPAPAPPAPASP 242
Query: 458 PWMGMPLPPP 467
+G L PP
Sbjct: 243 HTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/217 (25%), Positives = 62/217 (28%), Gaps = 81/217 (37%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLW----------------- 385
PP P A PPP P P P P P + FPPG W
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275
Query: 386 PPMGPFPP--------------------VPPPPSSGEAVAPPSTSAALSRPSGAATTTAA 425
PP P P VPPP + P + R AT A
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 426 GT-----------------------------SATAASATASGPGSGSAPEAG--PAPGFP 454
ATA ++ G A E P P P
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 455 FPPPWMGMPLPPPF-----AFPPMPV------PPAGF 480
PPP PLPPP A PP+P PPAGF
Sbjct: 396 LPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 15/118 (12%)
Query: 304 RLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLL 363
RLP FH + + P C + L+A+ PA SP + Q A PPP
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGE-LKATAPA-SPRLGQSQSQADERAGTPPPA- 393
Query: 364 PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAALSRPSGAA 420
PP PP PL PP P PP PP P + +A PP+ + S A
Sbjct: 394 -----------PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA 440
Score = 43.5 bits (101), Expect = 6e-04
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP-----FPPGMFPLWPPMG 389
RA P +PP P PA PPPAP PP P P + PP P P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP-- 443
Query: 390 PFPPVPPPPSSGEAVAP 406
P PP P + + AP
Sbjct: 444 --KPNPPSPENTASSAP 458
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/121 (33%), Positives = 48/121 (39%), Gaps = 18/121 (14%)
Query: 365 QPPNFPQGLL-PPFPPGMFP------LWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPS 417
+P + Q LL PP PPG P PP G P+P PPS+ A PP P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG--SPLPSPPST--APPPPPLLLEPPPPP 184
Query: 418 GAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPP 477
A A + T S P + P+ P P PP P PPP P P PP
Sbjct: 185 SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP----PAPPLAFLAPPPPPV---PAPAPP 237
Query: 478 A 478
A
Sbjct: 238 A 238
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 528 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 584
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 585 SVGTEEMPEDGEPDAA 600
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
Score = 32.0 bits (71), Expect = 1.7
Identities = 45/151 (29%), Positives = 54/151 (35%), Gaps = 25/151 (16%)
Query: 354 PPAPHPPP----LLPQPPNFPQGLL-PPFPPGMFP--LWPPMGPF-PPVPPPPSSGEAVA 405
P A + PP LLP P+ +L P PP P PP P PP + G A
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
Query: 406 PPSTSA------ALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPGFPFPPP 458
+TS A S P+ A+T T T+ + A SGP A P
Sbjct: 673 LKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQAR 732
Query: 459 WMGMP-----LP-----PPFAFPPMPVPPAG 479
G P LP AFPP P G
Sbjct: 733 GEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 68.2 bits (165), Expect = 2e-11
Identities = 70/256 (27%), Positives = 93/256 (36%), Gaps = 21/256 (8%)
Query: 337 SLPAQSPPPPEPADQGPPP---APHPPPLLP--QPPNFPQGLLPPFPPGMFPLWPPMGPF 391
S P+ +PPPP + PPP AP PPP+L PP+ P PP P PP+
Sbjct: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
Query: 392 PPVPPPPSSGEAVAPPSTSAALSR--PSGAAT--TTAAGTSATAASATASGPGSGSAPEA 447
P PPP + AP S +R P G T + + A AT + P A
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
G A G P P P + P PP PV + +E E + +RL
Sbjct: 285 GSALG-PNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPT 567
+ H I V P A+ + + S + + P
Sbjct: 343 SFH---------IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
Query: 568 PGASPPAPEMERPPAP 583
P PPAP + PPAP
Sbjct: 394 PPLPPPAPPLP-PPAP 408
Score = 51.6 bits (122), Expect = 2e-06
Identities = 43/130 (33%), Positives = 52/130 (40%), Gaps = 22/130 (16%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPN-----FPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
PPPP P PAP PP + +PP P PP PP + PP PPP
Sbjct: 140 PPPP------PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA---PPP 190
Query: 398 PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 457
P EA++PP T ++ S P+ A A A P PAP P P
Sbjct: 191 PPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP--------PPPVPAPAPPAPASP 242
Query: 458 PWMGMPLPPP 467
+G L PP
Sbjct: 243 HTVGTRLFPP 252
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/217 (25%), Positives = 62/217 (28%), Gaps = 81/217 (37%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLW----------------- 385
PP P A PPP P P P P P + FPPG W
Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275
Query: 386 PPMGPFPP--------------------VPPPPSSGEAVAPPSTSAALSRPSGAATTTAA 425
PP P P VPPP + P + R AT A
Sbjct: 276 PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
Query: 426 GT-----------------------------SATAASATASGPGSGSAPEAG--PAPGFP 454
ATA ++ G A E P P P
Sbjct: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395
Query: 455 FPPPWMGMPLPPPF-----AFPPMPV------PPAGF 480
PPP PLPPP A PP+P PPAGF
Sbjct: 396 LPPP--APPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 15/118 (12%)
Query: 304 RLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLL 363
RLP FH + + P C + L+A+ PA SP + Q A PPP
Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGE-LKATAPA-SPRLGQSQSQADERAGTPPPA- 393
Query: 364 PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP-PSSGEAVAPPSTSAALSRPSGAA 420
PP PP PL PP P PP PP P + +A PP+ + S A
Sbjct: 394 -----------PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA 440
Score = 43.5 bits (101), Expect = 6e-04
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 9/77 (11%)
Query: 335 RASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPP-----FPPGMFPLWPPMG 389
RA P +PP P PA PPPAP PP P P + PP P P P
Sbjct: 386 RAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP-- 443
Query: 390 PFPPVPPPPSSGEAVAP 406
P PP P + + AP
Sbjct: 444 --KPNPPSPENTASSAP 458
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/121 (33%), Positives = 48/121 (39%), Gaps = 18/121 (14%)
Query: 365 QPPNFPQGLL-PPFPPGMFP------LWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPS 417
+P + Q LL PP PPG P PP G P+P PPS+ A PP P
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG--SPLPSPPST--APPPPPLLLEPPPPP 184
Query: 418 GAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPP 477
A A + T S P + P+ P P PP P PPP P P PP
Sbjct: 185 SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP----PAPPLAFLAPPPPPV---PAPAPP 237
Query: 478 A 478
A
Sbjct: 238 A 238
Score = 32.7 bits (73), Expect = 1.0
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 528 ASLGPPRP--ATSVNSTEETATTVVAAASS-TSIPSSEATTPTPGASPPAPEMERPPAPE 584
A+LGP P ATS +T AT+ A AS+ T++P++ + S PA + E+P + E
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 585 SVGTEEMPEDGEPDAA 600
+ +G P A
Sbjct: 725 VSTPSQARGEGSPSEA 740
Score = 32.0 bits (71), Expect = 1.7
Identities = 45/151 (29%), Positives = 54/151 (35%), Gaps = 25/151 (16%)
Query: 354 PPAPHPPP----LLPQPPNFPQGLL-PPFPPGMFP--LWPPMGPF-PPVPPPPSSGEAVA 405
P A + PP LLP P+ +L P PP P PP P PP + G A
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP 672
Query: 406 PPSTSA------ALSRPSGAATTTAAGTSATAASATA-SGPGSGSAPEAGPAPGFPFPPP 458
+TS A S P+ A+T T T+ + A SGP A P
Sbjct: 673 LKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQAR 732
Query: 459 WMGMP-----LP-----PPFAFPPMPVPPAG 479
G P LP AFPP P G
Sbjct: 733 GEGSPSEATRLPTQGARSSAAFPPKTSPGGG 763
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 67.8 bits (164), Expect = 3e-11
Identities = 59/167 (35%), Positives = 62/167 (37%), Gaps = 59/167 (35%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFP---QGLLPPF-----------PPGMFPLWP-- 386
PPPP PA Q PP P PP P PP P Q L PP PP +FP P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFG 285
Query: 387 --PMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSA 444
P+GP PP PPPP G P P G
Sbjct: 286 QPPLGPLPPGPPPPVPGYGPPPGPPP----------------------------PQQGPP 317
Query: 445 PEAGPAPGFPFPPPWMGMPL----------PPPFAFPPMP-VPPAGF 480
P GP P P PP +G PL PPP A PP P V PA F
Sbjct: 318 PPPGPFP--PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 362
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/117 (37%), Positives = 47/117 (40%), Gaps = 8/117 (6%)
Query: 367 PNFPQGLLPPFPPGMFPLWPPMG-PFPPVPP-PPSSGEAVAPPSTSAAL--SRPSGAATT 422
P P G PPFP G P PP+G P PP PP PP G+ + PP RP
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
Query: 423 TAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAG 479
GP P GP PG PPP P PPP FPP P P G
Sbjct: 280 PGQPFGQPPLGPLPPGP-PPPVPGYGPPPG---PPPPQQGPPPPPGPFPPRPPGPLG 332
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/137 (37%), Positives = 53/137 (38%), Gaps = 22/137 (16%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
LP PP D+ PPP P QPP L P PPG P P GP PP PPP
Sbjct: 259 LPPPLAGPPNRGDRPPPPVLFPGQPFGQPP------LGPLPPGPPPPVPGYGP-PPGPPP 311
Query: 398 PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASAT-ASGPGSGSAPEAGPAPGFPFP 456
P G PP RP G G T A GP G+ P A FP
Sbjct: 312 PQQG---PPPPPGPFPPRPPG-----PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 457 PPW-MGMPL-----PPP 467
PP GMP PPP
Sbjct: 364 PPTNSGMPTSDSRGPPP 380
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/129 (34%), Positives = 52/129 (40%), Gaps = 30/129 (23%)
Query: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPP--MGPFPPVPPPPSS 400
PPPP P GPPP P PP P P P G PP PPG PL PP + P P +P PP
Sbjct: 296 PPPPVPG-YGPPPGPPPPQQGPPP---PPGPFPPRPPG--PLGPPLTLAPPPHLPGPPPG 349
Query: 401 GEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPF--PPP 458
AP A P+ + G ++ GP P P+ PPP
Sbjct: 350 APPPAPHVNPAFFPPPTNS--------------------GMPTSDSRGPPPTDPYGRPPP 389
Query: 459 WMGMPLPPP 467
+ PP
Sbjct: 390 YDRGDYGPP 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 46/137 (33%), Positives = 50/137 (36%), Gaps = 45/137 (32%)
Query: 350 DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPST 409
D+ P PA P PP FP G PP PP L PP P PP PPPP G+ + PP
Sbjct: 215 DRFPGPAGPGGP----PPPFPAGQTPPRPP----LGPPGPPGPPGPPPP--GQVLPPP-- 262
Query: 410 SAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPA-PGFPFPPPWMGMPLPPPF 468
A P G P PG PF P +G PLPP
Sbjct: 263 -------------------------LAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPG- 295
Query: 469 AFPPMPVPPAGFAGLTP 485
P PP G P
Sbjct: 296 -----PPPPVPGYGPPP 307
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/83 (38%), Positives = 33/83 (39%), Gaps = 19/83 (22%)
Query: 339 PAQSPPPP-------EPADQGPPPAPHPPPLLPQPPNFPQGLLPPFP---PGMFPLWPPM 388
P Q PPPP P GPP PPP LP P P G PP P P FP PP
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP---PPGAPPPAPHVNPAFFP--PPT 366
Query: 389 GPFPPVP----PPPSSGEAVAPP 407
P PPP+ PP
Sbjct: 367 NSGMPTSDSRGPPPTDPYGRPPP 389
Score = 29.6 bits (65), Expect = 8.6
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 21/114 (18%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPL---LP------QPPNFPQGLLPPFPPGMFPLWPPM 388
LP P P PA PA PPP +P PP P G PP+ G + PP
Sbjct: 343 LPGPPPGAPPPAPH-VNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDY--GPPG 399
Query: 389 GPFPPVPPPPSSGE---------AVAPPSTSAALSRPSGAATTTAAGTSATAAS 433
P S E A++ + S A+S S +A T TA S
Sbjct: 400 REMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAIS 453
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 67.4 bits (163), Expect = 4e-11
Identities = 52/156 (33%), Positives = 59/156 (37%), Gaps = 9/156 (5%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PPP P PP PP PP P P P + PF P P PP
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 399 SSGEAVAP--PSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSA-PEAGPAPGFPF 455
P P S + + PS A + AA S AS P S SA P P
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 507
Query: 456 PPPWMGMP---LPPPFAFPP---MPVPPAGFAGLTP 485
PP + P PP A PP +P PPA F G P
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
Score = 66.2 bits (160), Expect = 8e-11
Identities = 71/259 (27%), Positives = 86/259 (33%), Gaps = 37/259 (14%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PP G P LP PP P PP P L P P P PP
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 399 SSGEAVAPPSTSAALS------------RPSGAATTTAAGTSATAASAT--ASGPGSGSA 444
S A P AL+ P A + + + SAT + P S +A
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 445 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQ 504
P P P PP PPP A PP+ PP A P+ AL Q L +
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 505 SLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEAT 564
S +A L ++ T PP A V AA +P
Sbjct: 537 SFPGQAPFSPSASLPMSPLAT------PPPQAPP-----------VLAAPLLQVP----- 574
Query: 565 TPTPGASPPAPEMERPPAP 583
P+P ASP RPP P
Sbjct: 575 -PSPPASPTLQAPRRPPTP 592
Score = 60.1 bits (144), Expect = 6e-09
Identities = 72/256 (28%), Positives = 91/256 (35%), Gaps = 44/256 (17%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP PPM
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPM 491
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P PPP + APP A P A A S AS PG +
Sbjct: 492 SP-SATPPPQAPPPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 449 PAPGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSL 506
P P PPP PP A P + VPP+ A T LQ+
Sbjct: 549 SLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQAP 586
Query: 507 RNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS----E 562
R T + + LA PP P+ S +ST ++S+TS P +
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646
Query: 563 ATTPTPGASPPAPEME 578
+ A+ P P+ E
Sbjct: 647 SGPEGGAAASPPPDAE 662
Score = 56.6 bits (135), Expect = 7e-08
Identities = 85/316 (26%), Positives = 102/316 (32%), Gaps = 51/316 (16%)
Query: 336 ASLPAQSPPP-PEPADQGPPPAPHPPPLLPQ---PPNFPQGLLPP-----FPPGMFPLWP 386
A+ P+Q+PP P Q PP P PP+ P PP P L P PP P
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Query: 387 PMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPE 446
P +P PP+S AP S SA+L S AT AA P +P
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPLLQVPP----SPP 578
Query: 447 AGPAPGFPFPPPWMGM----------------PLPPPFAFPPMPVPPAGFAG------LT 484
A P P PP G P PPP P + AG T
Sbjct: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Query: 485 PEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPP------RPATS 538
PEELR + A + AA + LA G P PAT
Sbjct: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR--GPAPPLAFRGAPGAPLPWPPATG 696
Query: 539 VNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPD 598
S + T E+ TP PGA P P + G P
Sbjct: 697 PGSADGLCTIY-------ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 749
Query: 599 AAELRRRRLQKLESPV 614
A L L L++ V
Sbjct: 750 QARLGELPLGALQASV 765
Score = 54.3 bits (129), Expect = 3e-07
Identities = 81/293 (27%), Positives = 102/293 (34%), Gaps = 44/293 (15%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM-------FPLWP 386
L+A P Q PP + A P P P P Q PP P L
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336
Query: 387 PMGPFPPVPP-PPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAP 445
P+ PP P PPS +PP+T PS A T+ + T S S P S A
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATP-----PSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Query: 446 EAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQS 505
AP PP P PP A PP+ + A +P+ AL H Q
Sbjct: 392 PPPQAPPALALPPLQAPPSPP--ASPPL----SPLATPSPQAPNALAVHLLQ-------- 437
Query: 506 LRNIHTLLDAAMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEAT 564
A V A PP P S ++T + AA +P S
Sbjct: 438 ----------APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 487
Query: 565 TP--TPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 615
+P +P A+PP P+ P A + + P P L LQ L SP A
Sbjct: 488 SPPMSPSATPP-PQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPA 536
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/223 (26%), Positives = 78/223 (34%), Gaps = 33/223 (14%)
Query: 359 PPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTS----AALS 414
P P P P + G+ P P PP P S + + ST+ AA
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 415 RPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 474
RPS + + ++SAT + S P A P P A P P
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--------------AHPSQP 272
Query: 475 VPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR 534
P G L P ++ L L ++ L L S PP
Sbjct: 273 -KPKGLQALRPPQVTPPRKDAAPALGP-----------LSSSPLATPSPSAALQSQAPPT 320
Query: 535 -PATSVNS--TEETATTVVAAASSTSIPSSEATTPTPGASPPA 574
PAT +S T + AT + A S S P S T P+P A+PP+
Sbjct: 321 LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
Score = 41.2 bits (95), Expect = 0.003
Identities = 62/239 (25%), Positives = 78/239 (32%), Gaps = 40/239 (16%)
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATA 431
GLL P PPG P PPPP + A+ + A+ R A G +
Sbjct: 23 GLLTPRPPGS-----------PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 432 ASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLT--PEELR 489
SA +GP + SA + P P G PP P PV G A T P L
Sbjct: 72 ESAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL- 129
Query: 490 ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTV 549
G + + A R A+ P R A S + +T+
Sbjct: 130 ---GQKGLRISAEETVARG------------------KATEAPKRSALSAGARRDTSGPT 168
Query: 550 VAAASSTSIPSSEATTPTPGASPPAPEME-RPPAP---ESVGTEEMPEDGEPDAAELRR 604
S S A G PAP RPP +SV + EP A RR
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Score = 38.1 bits (87), Expect = 0.024
Identities = 66/268 (24%), Positives = 93/268 (34%), Gaps = 28/268 (10%)
Query: 330 RMDVLRASLPAQSPPPPEPA--DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPP 387
+ D +A A++P P PP +P PPP P P + L G PL
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAER 61
Query: 388 MGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEA 447
G P S+ A P+ SA S + A+ A+G A A + PG S+P
Sbjct: 62 AGGIGGATIPESAPR--AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 448 GPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLR 507
P P G+ + A T +A E +R L A +
Sbjct: 120 ASGTTRPGPLGQKGLRIS---------------AEETVARGKATEAPKRSALSAGARRDT 164
Query: 508 NIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATT-P 566
+ T + + +G PRPA S T S S S +TT P
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE----GPRKSVSSASEHSTTEP 220
Query: 567 TPGA--SPPAPEMERPPAPESVGTEEMP 592
+P A P A + PA S+ + P
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATP 248
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 67.4 bits (163), Expect = 4e-11
Identities = 52/156 (33%), Positives = 59/156 (37%), Gaps = 9/156 (5%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PPP P PP PP PP P P P + PF P P PP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 399 SSGEAVAP--PSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSA-PEAGPAPGFPF 455
P P S + + PS A + AA S AS P S SA P P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468
Query: 456 PPPWMGMP---LPPPFAFPP---MPVPPAGFAGLTP 485
PP + P PP A PP +P PPA F G P
Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Score = 66.2 bits (160), Expect = 8e-11
Identities = 71/259 (27%), Positives = 86/259 (33%), Gaps = 37/259 (14%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
P +PP G P LP PP P PP P L P P P PP
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 377
Query: 399 SSGEAVAPPSTSAALS------------RPSGAATTTAAGTSATAASAT--ASGPGSGSA 444
S A P AL+ P A + + + SAT + P S +A
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
Query: 445 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQ 504
P P P PP PPP A PP+ PP A P+ AL Q L +
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 505 SLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEAT 564
S +A L ++ T PP A V AA +P
Sbjct: 498 SFPGQAPFSPSASLPMSPLAT------PPPQAPP-----------VLAAPLLQVP----- 535
Query: 565 TPTPGASPPAPEMERPPAP 583
P+P ASP RPP P
Sbjct: 536 -PSPPASPTLQAPRRPPTP 553
Score = 60.1 bits (144), Expect = 6e-09
Identities = 72/256 (28%), Positives = 91/256 (35%), Gaps = 44/256 (17%)
Query: 338 LPAQSPPPPEPADQGPPPAPHPPPLLPQ-------PPNF--PQGLLPPFPPGMFPLWPPM 388
L A PPP P Q P P PP+ P PP+ P +PP PP PPM
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPM 452
Query: 389 GPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P PPP + APP A P A A S AS PG +
Sbjct: 453 SP-SATPPPQAPPPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 449 PAPGFPF--PPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSL 506
P P PPP PP A P + VPP+ A T LQ+
Sbjct: 510 SLPMSPLATPPP----QAPPVLAAPLLQVPPSPPASPT------------------LQAP 547
Query: 507 RNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSS----E 562
R T + + LA PP P+ S +ST ++S+TS P +
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 607
Query: 563 ATTPTPGASPPAPEME 578
+ A+ P P+ E
Sbjct: 608 SGPEGGAAASPPPDAE 623
Score = 57.0 bits (136), Expect = 5e-08
Identities = 79/290 (27%), Positives = 107/290 (36%), Gaps = 38/290 (13%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFP----LWPPMGPF 391
++ P SP P+ +G P AP P QP P+GL PP + P P +GP
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPS---QPK--PKGLQALRPPQVTPPRKDAAPALGPL 290
Query: 392 ---PPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAG 448
P P PS APPS SA S + + + AT + + + + S +
Sbjct: 291 SSSPLATPSPS-----APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 449 PAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRN 508
P PPP PP A PP+ PP+ A L L
Sbjct: 346 PLSPLATPPP----QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------- 393
Query: 509 IHTLLDAAMLQINQYLTVLASLGPP-RPATSVNSTEETATTVVAAASSTSIPSSEATTP- 566
+H L A V A PP P S ++T + AA +P S +P
Sbjct: 394 VHLL--QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 451
Query: 567 -TPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVA 615
+P A+PP P+ P A + + P P L LQ L SP A
Sbjct: 452 MSPSATPP-PQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPA 497
Score = 56.2 bits (134), Expect = 9e-08
Identities = 80/314 (25%), Positives = 95/314 (30%), Gaps = 58/314 (18%)
Query: 336 ASLPAQSPPPP----------EPADQGPPPAPHPP-PLLPQPPNFPQGLLP------PFP 378
A+ P Q PP P P Q PPP PP L PP P L P P
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495
Query: 379 PGMFPLWPPMGPFPPVP------PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAA 432
P FP P P +P PPP + +A P S P+
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555
Query: 433 SATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAG------LTPE 486
+ SGP A APG P PPP P + AG TPE
Sbjct: 556 DTSVSGPRLTLA----LAPG----------PPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 487 ELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPP------RPATSVN 540
ELR + A + AA + LA G P PAT
Sbjct: 602 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSR--GPAPPLAFRGAPGAPLPWPPATGPG 659
Query: 541 STEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAA 600
S + T E+ TP PGA P P + G P A
Sbjct: 660 SADGLCTIY-------ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 712
Query: 601 ELRRRRLQKLESPV 614
L L L++ V
Sbjct: 713 RLGELPLGALQASV 726
Score = 40.4 bits (93), Expect = 0.005
Identities = 63/233 (27%), Positives = 81/233 (34%), Gaps = 28/233 (12%)
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATA 431
GLL P PPG P PPPP + A+ + A+ R A G +
Sbjct: 23 GLLTPRPPG-----------SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 432 ASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLP---PPFAFPPMPVPPAGFAGL----- 483
SA +GP S P A G PP P P P A P G GL
Sbjct: 72 ESAPRAGPTRTSRPPAS-GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 484 -TPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNST 542
T +A E +R L A + + T + + +G PRPA S
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 543 EETATTVVAAASSTSIPSSEATT-PTPGA--SPPAPEMERPPAPESVGTEEMP 592
T S S S +TT P+P A P A + PA S+ + P
Sbjct: 191 PPTE----GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Score = 40.0 bits (92), Expect = 0.006
Identities = 76/324 (23%), Positives = 104/324 (32%), Gaps = 82/324 (25%)
Query: 330 RMDVLRASLPAQSPPPPEPA--DQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPL--- 384
+ D +A A++P P PP +P PPP P P + L G PL
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAER 61
Query: 385 ------------WPPMGPFPPVPPPPSSGEAVAPPSTSAA---LSRPSGAATTTAAGT-- 427
P GP PP S APP+ + + +S P A+ TT G
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 428 ---------------SATAASATASGPGSGSAPEAGPAPGFPFPP---------PWMGMP 463
AT A ++ +GP PG P P +G+P
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 181
Query: 464 LPPPFAFPPMPVP------------------------PAGFAGLTPEELRALEGHERQHL 499
P P A P P P+ GL R+L L
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS-SATPL 240
Query: 500 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR---------PATSVNSTEETATTVV 550
+ +S + A L +L PP+ PA S+ AT
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 551 AAASSTSIPSSEATTPTPGASPPA 574
+A S S P S T P+P A+PP+
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPS 324
Score = 32.3 bits (72), Expect = 1.3
Identities = 38/122 (31%), Positives = 45/122 (36%), Gaps = 14/122 (11%)
Query: 344 PPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPP-GMFPLWPPMGPFPPVPPPPSSGE 402
P P A +G P AP P P P + GL + G P G P P P +SG
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGS-ADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 694
Query: 403 AVAPPSTSAALSR----------PSGA--ATTTAAGTSATAASATASGPGSGSAPEAGPA 450
A + + A SR P GA A+ S T A A G GS G A
Sbjct: 695 KAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 754
Query: 451 PG 452
G
Sbjct: 755 EG 756
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 67.4 bits (163), Expect = 4e-11
Identities = 70/287 (24%), Positives = 101/287 (35%), Gaps = 23/287 (8%)
Query: 306 PCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQ 365
P H+ S + S F T + +A + + + P PP +P P + P
Sbjct: 563 PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLV---PPLSPQPKIVTPY 619
Query: 366 PPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAA 425
+ P LPP PP PP P PP PPPP + + PS +A +T T
Sbjct: 620 TASQPSPPLPPPPP------PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673
Query: 426 GTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTP 485
++ + A P P PP + P PPP PP P P + A L P
Sbjct: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP---PPPPTPGSAMAQLKP 730
Query: 486 EELR-ALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSV---NS 541
+L ++ +++I + L PP+P ++ S
Sbjct: 731 APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790
Query: 542 TEETATTVVAAASSTSIPSSEATTPTPG-------ASPPAPEMERPP 581
T+ A V AA T P P SPP P + PP
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
Score = 66.2 bits (160), Expect = 8e-11
Identities = 72/271 (26%), Positives = 96/271 (35%), Gaps = 41/271 (15%)
Query: 343 PPPPEPADQGPPPAPHPP--PLLPQP--PNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
PPPP P PPP P L P P P+ PQ PP P + + PP PPPP
Sbjct: 711 PPPPPP----PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 399 SSGEAVAPPST--SAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 456
A PP ++ P+ +T T A AA T + P P A P FP
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP----VPPAKKQPAFP-- 820
Query: 457 PPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAA 516
+PP PP+PVPP L + + L + +++
Sbjct: 821 ----ASYIPPSPPTPPVPVPPP-----------TLPKQQSFCAKPPPSPLSPVPSVVKQI 865
Query: 517 MLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAA----SSTSIPSSEATTPTPGAS- 571
Q T A P N ++ V A SS +PS + P P +S
Sbjct: 866 ASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSL 925
Query: 572 -----PPAPEMERPPAPESVGTEEMPEDGEP 597
PP+P PP P + + G P
Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Score = 64.3 bits (155), Expect = 3e-10
Identities = 60/202 (29%), Positives = 71/202 (35%), Gaps = 51/202 (25%)
Query: 333 VLRASLPAQSPPPPEPADQGPPPAPHPP---------------------PLLPQPPNFPQ 371
+ + + P PPPP PA PP AP P P P PP P
Sbjct: 755 ITQVAPPTPPPPPPIPAPL-PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPA 813
Query: 372 GLLPPFPPGMFPLWPPMGPFPPVP------------PPPS------------SGEAVAPP 407
P FP P PP P P P PPPS + + PP
Sbjct: 814 KKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP 873
Query: 408 STSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGM--PLP 465
+ A S+P A S A A S S P P+P FP PPP + P P
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPS-SIPV--PSPDFPPPPPESSLVFPPP 930
Query: 466 PPFAFPPMPVPPAGFAGLTPEE 487
PP P P PP A TP++
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDK 952
Score = 50.4 bits (119), Expect = 5e-06
Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 40/170 (23%)
Query: 338 LPAQSPPPPEP---------------ADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMF 382
+ +Q PPPP P A Q PP P P P PP PP
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924
Query: 383 PLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSG 442
++PP P P PPP PP T++ SG+ + TS+ P
Sbjct: 925 LVFPPPPPSPVPAPPP------PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978
Query: 443 SAPEAG-----PAPGFP---------FPPPWMGMP----LPPPFAFPPMP 474
S+ ++ P P P PP G P LPPP A PP P
Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP-AAPPKP 1027
Score = 49.7 bits (117), Expect = 8e-06
Identities = 72/315 (22%), Positives = 108/315 (34%), Gaps = 67/315 (21%)
Query: 336 ASLPAQSP----PPPEPADQGPPPAPHPPPLLPQPP---------------------NFP 370
+S+P SP PPPE + PPP P P P P PP + P
Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP 966
Query: 371 QGLLPP-FPPGMFPLWPPMGPFPPVPPPPSSGEAVA---PPSTSAALSR--------PSG 418
G PP P + G P P PS V+ PP+ S + S+ P
Sbjct: 967 GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK 1026
Query: 419 AATTTAAGTS---------ATAASATASGPGSGSAPEAGPAPG---FPFPPPWMGMPLPP 466
+G + +A + SG G S E P FP PPP +PLPP
Sbjct: 1027 PGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPP 1086
Query: 467 PFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSL-------RNIHTLLDAAMLQ 519
PA F+G T ++ + +Q + ++ RN T L A +
Sbjct: 1087 IEI-------PAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEIS 1139
Query: 520 INQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEME- 578
+ + P P +S++ + SI + + + P M+
Sbjct: 1140 EQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDD 1199
Query: 579 ---RPPAPESVGTEE 590
PP PE + ++
Sbjct: 1200 MALPPPPPELLSDQQ 1214
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 66.2 bits (160), Expect = 8e-11
Identities = 89/333 (26%), Positives = 113/333 (33%), Gaps = 86/333 (25%)
Query: 334 LRASLPAQSPPPPEPADQGP------------------------PPAPHPPPLLPQPPNF 369
L ++ P PP P P+ GP P PH P+ P P +
Sbjct: 763 LGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALY 822
Query: 370 PQ-------GLLPPFPP----------GMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAA 412
P GL+P P G+ P PP+ P PPP SG P + A
Sbjct: 823 PAPAYTPELGLVPRSSPQHGVVSSPYVGVGPA-PPVAGLPSAPPPQFSG-----PELAMA 876
Query: 413 LSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFP- 471
+ RP ATTT A S TA P AP P P FP PPP PLP P+ +P
Sbjct: 877 V-RP---ATTTVDSIQAPIPSHTAPRPNPTPAP---PPPCFPVPPP---QPLPTPYTYPA 926
Query: 472 --PMPVP---------PAGFAG--LTPEELRALEGHERQHL--EARLQSLRNIHTLLDAA 516
P+P PAGF + P+ + H Q + Q L H L
Sbjct: 927 GAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986
Query: 517 MLQINQYLTVLASLGP----PRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASP 572
Q +L P P+P T + + +P+ P P P
Sbjct: 987 -----QAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP 1041
Query: 573 PAPEMERPPAPESVGTEEMPEDGEPDAAELRRR 605
P P P P + G P AA L R
Sbjct: 1042 PQP----PHPPLAYGPAPSTRPMGPQAAPLTIR 1070
Score = 60.8 bits (146), Expect = 3e-09
Identities = 50/176 (28%), Positives = 61/176 (34%), Gaps = 30/176 (17%)
Query: 328 TCRMDVLRASLPAQSPPPPEPADQGPPPA-PHPPPL-LPQPPNFPQGLLPPFP------- 378
T +D ++A +P+ + P P P PPP P PPP LP P +P G P P
Sbjct: 881 TTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSS 940
Query: 379 --PGMFPLWPPMGPFPPVPPPPSSGEAVAP-------PSTSAALSRPSGAATTTAAGTSA 429
P FP P +GP P P P +A P P L P
Sbjct: 941 GIPAGFPA-PRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYP 999
Query: 430 TAASATASG-----------PGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP 474
A G PG P + PFP P P PP A+ P P
Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAP 1055
Score = 44.3 bits (103), Expect = 3e-04
Identities = 57/199 (28%), Positives = 64/199 (32%), Gaps = 64/199 (32%)
Query: 341 QSPPP------------PEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPM 388
Q PPP P PA G P P P P PQPP+ PP G P PM
Sbjct: 1009 QPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP--PQPPH------PPLAYGPAPSTRPM 1060
Query: 389 GP---------------FPPVP-----PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTS 428
GP P P P PS G PP RP A
Sbjct: 1061 GPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPP-------RPPAAEPPPCLRRG 1113
Query: 429 ATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEEL 488
A AA +S P S P G P P V A G P+ L
Sbjct: 1114 AAAADLLSSSPESQHGGTQSPGGGQPL--------------LQPTKVDAA--EGRRPQAL 1157
Query: 489 RALEGHERQHLEARLQSLR 507
R +E +H E RL+ L+
Sbjct: 1158 RLIERDPYEHPE-RLRQLQ 1175
Score = 39.7 bits (91), Expect = 0.008
Identities = 73/285 (25%), Positives = 93/285 (32%), Gaps = 90/285 (31%)
Query: 323 QQTCPT---CRMDVLRASLPAQSPPPP-------------EPADQGPPPAPH---PPPLL 363
Q TC R +L L + PP P E + G PP PP ++
Sbjct: 694 QSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMV 753
Query: 364 --PQPPNFPQGLLPP--FPPGMFPLWPPMGPF---PPVPPPPSSGEAVAPPSTSAALSRP 416
P+ P+ G P FPP FP GP P+PP SG P+ P
Sbjct: 754 AGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSG-----PTQLIQPRAP 808
Query: 417 SGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP 476
A A G + A A P G P + P G P++G+ PP A P P
Sbjct: 809 GPHAMPVAPGPALYPAPAYT--PELGLVPRSSPQHGV-VSSPYVGVGPAPPVAGLPS-AP 864
Query: 477 PAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPA 536
P F+G PE A+ RPA
Sbjct: 865 PPQFSG--PELAMAV------------------------------------------RPA 880
Query: 537 TSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPP 581
T+ T ++ A IPS A P P +PP P PP
Sbjct: 881 TT------TVDSIQAP-----IPSHTAPRPNPTPAPPPPCFPVPP 914
Score = 35.4 bits (80), Expect = 0.16
Identities = 29/82 (35%), Positives = 32/82 (39%), Gaps = 7/82 (8%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
ASLP + PP G PPA P P P + P L P P P P P P
Sbjct: 1518 ASLPGPAEPP------GLPPASLPEST-PIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSS 1570
Query: 396 PPPSSGEAVAPPSTSAALSRPS 417
PPSS + T A S S
Sbjct: 1571 GPPSSSLELLASLTPEAFSLDS 1592
Score = 30.4 bits (67), Expect = 5.0
Identities = 29/105 (27%), Positives = 40/105 (38%), Gaps = 10/105 (9%)
Query: 334 LRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMG-PFP 392
++A++ S PP + P A P P +PP P LP P PP+ P P
Sbjct: 1498 IQATIAKLSIRPPGGLES--PVASLPGPA--EPPGLPPASLPESTPIPSSSPPPLSSPLP 1553
Query: 393 PVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATAS 437
P P PP A S P ++ A + A S +S
Sbjct: 1554 EAPQPKEE-----PPVPEAPSSGPPSSSLELLASLTPEAFSLDSS 1593
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 66.2 bits (160), Expect = 8e-11
Identities = 57/151 (37%), Positives = 67/151 (44%), Gaps = 18/151 (11%)
Query: 339 PAQSPPPPE--PADQGPPPAPHPPPLLPQPPN------FPQGLLPPFPPGMFPLWPPMGP 390
PA +PP P+ PA P AP PP P P P+G P PP P P GP
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA--PTPPAATPPSPKGGP 1000
Query: 391 FPPVPPPPSSGEAVAPPS---TSAALSRPSGAATTTAAGTSATAAS--ATASGPGSGSAP 445
P P + AV PPS + AA P GA+T AA + S AT G+ + P
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 446 EAG-PAP-GFPFPPPWMGMPLPPPFAFPPMP 474
A P+P G P P G P PP A PP P
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPA-ATPPSP 1090
Score = 65.1 bits (157), Expect = 2e-10
Identities = 73/268 (27%), Positives = 90/268 (33%), Gaps = 60/268 (22%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPP 398
PA +PP P+ PPP P PP+ GL P P G P P PP
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG--------APTTPAATPP 1180
Query: 399 SSGEAVAPPSTSAALSRPS--------GAATTTAAGTSATAASATASGPGSGSAPEAGPA 450
S +A PS A + P+ G AT + G T A+ S G + P A
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 451 PGFPF--PPPWMGMPLPPP---FAFPPMPVPPAGFAGL-TPEELRALEGHERQHLEARLQ 504
P P PP G P PP PP PP+ GL TP A
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP----------- 1289
Query: 505 SLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEAT 564
A + PP P ++ AA+ S S T
Sbjct: 1290 -----------------------AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 565 TPTPGASPPAPEMERPPAPESVGTEEMP 592
P GA P P PP+P+ GT +P
Sbjct: 1327 PPPKGA--PTPPAVTPPSPK--GTPTLP 1350
Score = 64.3 bits (155), Expect = 3e-10
Identities = 76/274 (27%), Positives = 92/274 (33%), Gaps = 60/274 (21%)
Query: 339 PAQSPPPPE------PADQGPPPAPHPPPLLPQP---PNFPQGLLPPFPPGMFPLWPPMG 389
PA +PP P+ P +G P P LP P P P P PP P P G
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093
Query: 390 PFPPVPPPPSSGEAVAPPSTSAALSRP--SGAATTTAAGT-SATAASATASGPGSGSAPE 446
P P P A PPS L+ P GA TT AA S AT G+ + P
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 447 AGPAPGFPFPPPWMGMPLPPPFAFP--PMPVPPAGFAGL-TPEELRALEGHERQHLEARL 503
A P P P G+ PPP P P PP+ GL TP A
Sbjct: 1154 ATP------PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA------------- 1194
Query: 504 QSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEA 563
+ PP P + + AA+ S P
Sbjct: 1195 ---------------------PTTPAATPPSPKGGLATPSPKGAPTTPAATPPS-PKGGL 1232
Query: 564 TTPTPGASPPAPEMERPPAPESVGTEEMPEDGEP 597
TP+P +P P PP+P+ G P G P
Sbjct: 1233 ATPSPKGAPTTP-AATPPSPKG-GPATPPPKGAP 1264
Score = 63.9 bits (154), Expect = 4e-10
Identities = 78/281 (27%), Positives = 102/281 (36%), Gaps = 59/281 (20%)
Query: 339 PAQSPPPPEPADQGPPP--APH----PPPL----LPQPPN----FPQGLLPPFPPGMFPL 384
PA +PP P+ PPP AP PP L PP+ P + PP P G
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 385 WPPMG-PFPP--VPPPPSSGEAVAPPS---TSAALSRPS--GAATTTAAGTSATAASATA 436
PP G P PP PP P PP T A++ PS G T A S+ T
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 437 SGPGSGSAPEAGPA----PGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALE 492
S + P A P+ P P P G +P P P P L+P++ A
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP----AVIPLSPKKAPATP 1419
Query: 493 GHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAA 552
+ A LT P T V+ + AT+
Sbjct: 1420 ------------------VTREGAATPSKGDLT-------PPAVTPVSLKKAPATSAPKG 1454
Query: 553 ASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPE 593
+T PSS+ P +PP+P + PPAP+ V T P+
Sbjct: 1455 GPAT--PSSKGDPTLPAVTPPSP--KEPPAPKQVATSSSPK 1491
Score = 60.8 bits (146), Expect = 3e-09
Identities = 70/271 (25%), Positives = 86/271 (31%), Gaps = 56/271 (20%)
Query: 339 PAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLP---PFPPGMFPLWPPMGPFPPVP 395
PA P PA +P P P P P P PP P P GP P P
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 396 PPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSA---PEAGPAPG 452
+ A PPS P G T + + T +AT P G A P+ P P
Sbjct: 960 KWAPTPPAATPPS-------PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 453 FPFPPPWMGMPLPPPF----AFPPMPVPPA--GFAGLTPEELRALEGHERQHLEARLQSL 506
PP G P PF + PP PP+ G TP
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP--------------------- 1051
Query: 507 RNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTP 566
L T A+L P+ + S + T A S P TP
Sbjct: 1052 -----------LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS---PKGGPATP 1097
Query: 567 TPGASPPAPEMERPPAPESVGTEEMPEDGEP 597
+P + P P PP+P+ G P G P
Sbjct: 1098 SPKGA-PMPPAATPPSPKG-GLATPPHKGAP 1126
Score = 60.8 bits (146), Expect = 3e-09
Identities = 78/289 (26%), Positives = 95/289 (32%), Gaps = 67/289 (23%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPN------------FPQGLLPPFPPGMFP 383
A+LP+ P P+ +G AP PP P P P PP P G
Sbjct: 1062 ATLPSPKGGPATPSLKG---APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118
Query: 384 LWPPMG-PFPP--VPPPPSSGEAVAPPS---TSAALSRPS---GAATTTAAGTSATAASA 434
P G P P PP P G A PP T+ A + PS G AT G T A+
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
Query: 435 TASGPGSGSAPEAGPAPGFPF---PPPWMGMPLPPPFAFP--PMPVPPAGFAGL-TPEEL 488
S G + P AP P P P G+ P P P P PP+ GL TP
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 489 RALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATT 548
A + PP P +
Sbjct: 1239 GA----------------------------------PTTPAATPPSPKGGPATPPPKGAP 1264
Query: 549 VVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEP 597
AA+ S+ AT P GA P P + PP+P+ G P G P
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGA--PNPAVVTPPSPKG-GPATSPPKGAP 1310
Score = 60.8 bits (146), Expect = 3e-09
Identities = 76/295 (25%), Positives = 109/295 (36%), Gaps = 56/295 (18%)
Query: 336 ASLPAQSPPPPEPADQG----PPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPF 391
+S +PP P+ +G PP+P P +P P P P + PL P P
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS------PAVIPLSPKKAPA 1417
Query: 392 PPV----PPPPSSGEAVAPPSTSAAL------SRPSGAATTTAAGTSATAASATASGPGS 441
PV PS G+ P T +L S P G T ++ T + T P
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 442 GSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMP-VPPAGFAGLTPEELRALEGHERQHL- 499
AP+ P P P P P +P V P+ +P+E+ A R +
Sbjct: 1478 PPAPKQVATSSSPKKAP----ATPAPMGAPTLPAVIPS-----SPKEVPATPSSRRDPIA 1528
Query: 500 -EARLQSLRNIHTLLDAAMLQINQYLTV-----LASLGPPRPATSVNSTEETATTVVAAA 553
A L S + TL L I +TV ++ P+ A + S++E ++
Sbjct: 1529 PTATLLSKKTPATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 554 SS----------------TSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 592
S+ TS EA TP P +PP+PE + P P GT P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPE-KGPATPAPKGTPTSP 1640
Score = 57.4 bits (137), Expect = 4e-08
Identities = 80/304 (26%), Positives = 111/304 (36%), Gaps = 52/304 (17%)
Query: 339 PAQSPPPPEPADQGPPP--APHPPPLLPQPP--------------------NFPQGLLPP 376
PA +PP P+ + PPP AP PP + P P + +G PP
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 377 FP-------PGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRP---SGAATTTAAG 426
P M P P GP P P + AV P S A + P GAAT +
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 427 TSATAASATA--SGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVP-------- 476
+ A + + P + SAP+ GPA P + PP PP P
Sbjct: 1433 LTPPAVTPVSLKKAPAT-SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 477 --PAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPR 534
PA A + L A+ + + A S R+ A +L T+
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD-PIAPTATLLSKKTPATLAPKEALIP 1550
Query: 535 PATSVNSTEETATTVVAAASSTSIPSSEATTP---TPGASPPAP---EMERPPAPESVGT 588
PA +V S ++T + + S EA++P TP AP E+ PPA S
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610
Query: 589 EEMP 592
+E P
Sbjct: 1611 KEAP 1614
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/277 (24%), Positives = 93/277 (33%), Gaps = 66/277 (23%)
Query: 336 ASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVP 395
+S A SPP P+ P+P L+P P P PP + P P GP P P
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKEL-LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Query: 396 PPPSSGEAVAPPSTSAAL--SRPSGAATTTAAGTSATAASA---TASGPGS------GSA 444
G +PP T ++L S S A+ T G + AS GP + A
Sbjct: 1634 ----KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA 1689
Query: 445 PEAGP---APGFPFPPPWMGMPLPPPFAFPPMP----------VPPAGFAGLTPEELRAL 491
PE+ P AP P PP P V PA + + +
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA 1749
Query: 492 EGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVA 551
+G + H + GP P S + +T + A
Sbjct: 1750 KGKDASH-----------------------------SPKGPLAPPES-----KASTPLTA 1775
Query: 552 AASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGT 588
AA +P E+ + + SPP + P AP V T
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPP---VSLPLAPSPVPT 1809
Score = 43.1 bits (100), Expect = 7e-04
Identities = 56/235 (23%), Positives = 76/235 (32%), Gaps = 36/235 (15%)
Query: 364 PQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTT 423
P PP+ P+G P P + PL P PP P S + P A P A +
Sbjct: 856 PTPPS-PKGA--PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 424 AAGTSATAASATASGPG--SGSAPEAGPAPGFPFPPPWMGMPLPPPFAF---PPMPVPPA 478
+S A AT + G + +P+ P P PP G P P + PP PP+
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 479 GFAG-LTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPAT 537
G TP A A S + GP P+
Sbjct: 973 PKGGPATPSPKGA-----PTPPAATPPSPKG----------------------GPATPSP 1005
Query: 538 SVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 592
T T S + P + + P A+PP+P+ P G P
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Score = 39.3 bits (90), Expect = 0.011
Identities = 67/289 (23%), Positives = 93/289 (32%), Gaps = 58/289 (20%)
Query: 327 PTCRMDVLRASLPAQSPPPPEPADQGP---PPAPHPPPLLPQP--PNFPQGLLPPFPPGM 381
PT +VL A P +P P +GP + PP+ P P N +G
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG--------- 1728
Query: 382 FPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSG--AATTTAAGTSATAASATASGP 439
P+ P P P ++ A P G A + A T TAA+ P
Sbjct: 1729 -----PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783
Query: 440 GSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHL 499
PE+ P PP + +PL P P+P P L LE +
Sbjct: 1784 ----KPESASVSAAPSPP--VSLPLAP----SPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
Query: 500 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 559
A L L PP P S ++ + S IP
Sbjct: 1834 PADEDE---------------------LLPLIPPEP-ISGGVPFQSVLVNMPTPKSAGIP 1871
Query: 560 SSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQ 608
PTP A P + + ES E +PE E D+ + ++ Q
Sbjct: 1872 -----VPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Score = 37.4 bits (85), Expect = 0.041
Identities = 63/301 (20%), Positives = 92/301 (30%), Gaps = 34/301 (11%)
Query: 323 QQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAP------HPPPLLP---QPPNFP--- 370
Q TC VL +P P P P PP H L P P P
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
Query: 371 ---------QGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAAT 421
+G L PL + P PP+ + P + LS P
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSP--QTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832
Query: 422 TTAAGTSATAASATASGPGSGSAP-----EAGPAPGFPFPPPWMGMPLPPPFAFPP---- 472
+ ++ + + P + +P + P P P G+ LPP P
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 473 MPVPPAGFAGLTPEELRALEGHERQHLEARLQSL-RNIHTLLDAAMLQINQYLTVLASLG 531
+P P G A P++ AL +AR + I T + G
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 532 PPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEM 591
P + + A T + + PS + P A+PP+P+ P P G
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK-GGPATPSPKGAPTP 1011
Query: 592 P 592
P
Sbjct: 1012 P 1012
Score = 36.2 bits (82), Expect = 0.091
Identities = 48/196 (24%), Positives = 69/196 (35%), Gaps = 44/196 (22%)
Query: 386 PPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAP 445
PP P P P ++ +A PS S S P ++ SG+A
Sbjct: 47 PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS---------------SGTAL 91
Query: 446 EAGPAPGFP-FPPPWMGMPLPP-------PFAFPPMPVPPAGFAGLTPEELRALEGHERQ 497
G AP P F P +G P+ P P P + P+ A P L AL H Q
Sbjct: 92 PLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA---PLALVALAPHSVQ 148
Query: 498 HLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTS 557
A +L + + A+ + +T+ A + P P T++N
Sbjct: 149 KSSAFPPNL--LTSPPSVAVAESGSVITLSAPIAPSEPKTNLN----------------K 190
Query: 558 IPSSEATTPTPGASPP 573
+PS P SPP
Sbjct: 191 VPSEVVPNPKGTPSPP 206
Score = 35.4 bits (80), Expect = 0.16
Identities = 53/207 (25%), Positives = 69/207 (33%), Gaps = 22/207 (10%)
Query: 401 GEAVAP-PSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAP-GFPFPPP 458
GEA P+T L +P A T +SA + +A PG P PAP P
Sbjct: 3 GEATETVPATEQELPQPQ-AETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 459 WMGMPLPPP--FAFPPMPVP----------PAGFAGLTPEELRALEGHERQHLEARLQSL 506
P P P A P+ VP P G A P L L G L S
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 507 RNIHTL-------LDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 559
TL A++ + + +S PP TS S + V S+ P
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 560 SSEATTPTPGASPPAPEMERPPAPESV 586
S T S P + P+P +
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCI 208
Score = 30.8 bits (68), Expect = 3.8
Identities = 64/294 (21%), Positives = 100/294 (34%), Gaps = 79/294 (26%)
Query: 341 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGM--FPLWPPMG--------- 389
Q+ P P+ Q +P P L P+ + L P P G + P+G
Sbjct: 564 QAAPKNSPSFQSTSSSPEIP-LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK 622
Query: 390 ----PFPPVPPPPSSGEAVAPPSTSAALSR--PSGAATTTAAGTSATAASATASGPGSGS 443
P P + P + L P+G A TTA GTS +A+ G+ S
Sbjct: 623 TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVS 682
Query: 444 -APEAGP------------------APGFPFP----PPWMGMPLPP--PFAFPPMPVPPA 478
AP+ P P P P P + L P P + P +PPA
Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA 742
Query: 479 GFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATS 538
G TP + ++G ++ ++L P +
Sbjct: 743 G----TPPGTKKVDG------------------------------ISHTSALAPVASSPK 768
Query: 539 VNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMP 592
TE++ + A ASS + A +P+P +P+ +RPP + + P
Sbjct: 769 ECPTEDSGAS--ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,616,974
Number of Sequences: 37866
Number of extensions: 2166749
Number of successful extensions: 65287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1025
Number of HSP's successfully gapped in prelim test: 1887
Number of HSP's that attempted gapping in prelim test: 20144
Number of HSP's gapped (non-prelim): 22498
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.