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Search of human proteins with 26667183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26667183 calcium/calmodulin-dependent protein kinase II
delta isoform 1 [Homo sapiens]
(478 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 978 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 978 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 978 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 976 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 970 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 969 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 886 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 872 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 870 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 868 0.0
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 867 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 865 0.0
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 862 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 861 0.0
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 857 0.0
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 853 0.0
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 853 0.0
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 844 0.0
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 829 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 795 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 612 e-175
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 286 4e-77
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 286 4e-77
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 286 4e-77
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 249 4e-66
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 236 3e-62
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 236 4e-62
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 228 9e-60
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 226 4e-59
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 224 1e-58
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 978 bits (2529), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 978 bits (2529), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 978 bits (2529), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 976 bits (2524), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPI 477
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPI
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPI 477
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 970 bits (2507), Expect = 0.0
Identities = 478/489 (97%), Positives = 478/489 (97%), Gaps = 11/489 (2%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVK-----------ESTESSNTTIEDEDVKARKQE 349
KGAILTTMLATRNFSAAKSLLKKPDGVK ESTESSNTTIEDEDVKARKQE
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKKRKSSSSVQMMESTESSNTTIEDEDVKARKQE 360
Query: 350 IIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKP 409
IIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKP
Sbjct: 361 IIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKP 420
Query: 410 IHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHR 469
IHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHR
Sbjct: 421 IHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHR 480
Query: 470 SGSPTVPIK 478
SGSPTVPIK
Sbjct: 481 SGSPTVPIK 489
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 969 bits (2504), Expect = 0.0
Identities = 478/492 (97%), Positives = 478/492 (97%), Gaps = 14/492 (2%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGV--------------KESTESSNTTIEDEDVKAR 346
KGAILTTMLATRNFSAAKSLLKKPDGV KESTESSNTTIEDEDVKAR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
Query: 347 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 406
KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS
Sbjct: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
Query: 407 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 466
NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH
Sbjct: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
Query: 467 FHRSGSPTVPIK 478
FHRSGSPTVPIK
Sbjct: 481 FHRSGSPTVPIK 492
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 886 bits (2289), Expect = 0.0
Identities = 425/479 (88%), Positives = 456/479 (95%), Gaps = 1/479 (0%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 359
KGAILTTMLATRNFSAAKSLL KK DGVKES++S+NTTIEDED KARKQEIIK TEQLIE
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 360
Query: 360 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 419
A+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHV
Sbjct: 361 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 420
Query: 420 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
H++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 421 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 479
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 872 bits (2254), Expect = 0.0
Identities = 425/503 (84%), Positives = 456/503 (90%), Gaps = 25/503 (4%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVK------------------------ESTESSN 335
KGAILTTMLATRNFSAAKSLL KK DGVK ES++S+N
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 360
Query: 336 TTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFH 395
TTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFH
Sbjct: 361 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 420
Query: 396 RFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVW 455
RFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVW
Sbjct: 421 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 480
Query: 456 HRRDGKWQNVHFHRSGSPTVPIK 478
HRRDGKWQNVHFH SG+P P++
Sbjct: 481 HRRDGKWQNVHFHCSGAPVAPLQ 503
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 870 bits (2248), Expect = 0.0
Identities = 421/495 (85%), Positives = 452/495 (91%), Gaps = 17/495 (3%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKK-----------------PDGVKESTESSNTTIEDEDV 343
KGAILTTML +RNFSAAKSLL K DG+K STES NTT EDED+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
Query: 344 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 403
K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
Query: 404 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 463
SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW
Sbjct: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
Query: 464 NVHFHRSGSPTVPIK 478
NVH+H SG+P P++
Sbjct: 481 NVHYHCSGAPAAPLQ 495
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 868 bits (2244), Expect = 0.0
Identities = 423/518 (81%), Positives = 455/518 (87%), Gaps = 40/518 (7%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKP------------------------------------ 324
KGAILTTMLATRNFSAAKSLL K
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 360
Query: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+F
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 420
Query: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
EPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 421 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480
Query: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 867 bits (2239), Expect = 0.0
Identities = 421/504 (83%), Positives = 452/504 (89%), Gaps = 26/504 (5%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKK--------------------------PDGVKESTESS 334
KGAILTTML +RNFSAAKSLL K DG+K STES
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
Query: 335 NTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDF 394
NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDF
Sbjct: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
Query: 395 HRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRV 454
H+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRV
Sbjct: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
Query: 455 WHRRDGKWQNVHFHRSGSPTVPIK 478
WHRRDGKW NVH+H SG+P P++
Sbjct: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 865 bits (2236), Expect = 0.0
Identities = 415/474 (87%), Positives = 448/474 (94%), Gaps = 1/474 (0%)
Query: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
Query: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
Query: 303 AILTTMLATRNFSAAKS-LLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAI 361
AILTTMLATRNFS KS KK DGVKES+ES+NTTIEDED K RKQEIIKVTEQLIEAI
Sbjct: 302 AILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAI 361
Query: 362 NNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHL 421
+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+HT ILNPH+HL
Sbjct: 362 SNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHL 421
Query: 422 VGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTV 475
+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRSG+P+V
Sbjct: 422 MGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSV 475
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 862 bits (2228), Expect = 0.0
Identities = 421/517 (81%), Positives = 452/517 (87%), Gaps = 39/517 (7%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVK-------------------------------- 328
KGAILTTMLATRNFSA L KK DGVK
Sbjct: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
Query: 329 -------ESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 381
ES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FE
Sbjct: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
Query: 382 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 441
PEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
Query: 442 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 861 bits (2225), Expect = 0.0
Identities = 421/518 (81%), Positives = 452/518 (87%), Gaps = 40/518 (7%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323
KGAILTTML +RNFSAAKSLL K
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360
Query: 324 ---PDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
DG+K STES NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+F
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 420
Query: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
EPEALGNLVEGMDFH+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 421 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480
Query: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
G P+T QSEETRVWHRRDGKW NVH+H SG+P P++
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 857 bits (2214), Expect = 0.0
Identities = 415/485 (85%), Positives = 448/485 (92%), Gaps = 12/485 (2%)
Query: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
Query: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
Query: 303 AILTTMLATRNFSAAKS-LLKKPDGVK-----------ESTESSNTTIEDEDVKARKQEI 350
AILTTMLATRNFS KS KK DGVK ES+ES+NTTIEDED K RKQEI
Sbjct: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
Query: 351 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 410
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
Query: 411 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 470
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
Query: 471 GSPTV 475
G+P+V
Sbjct: 482 GAPSV 486
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 853 bits (2205), Expect = 0.0
Identities = 421/527 (79%), Positives = 452/527 (85%), Gaps = 49/527 (9%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFS---------------------AAKSLLKK---------------- 323
KGAILTTML +RNFS AAKSLL K
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVH 360
Query: 324 ------------PDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTK 371
DG+K STES NTT EDED+K RKQEIIK+TEQLIEAINNGDFEAYTK
Sbjct: 361 LMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 420
Query: 372 ICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAY 431
ICDPGLT+FEPEALGNLVEGMDFH+FYFEN LSK++KPIHT ILNPHVH++G+DAACIAY
Sbjct: 421 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 480
Query: 432 IRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
IRLTQY+DG G P+T QSEETRVWHRRDGKW NVH+H SG+P P++
Sbjct: 481 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 853 bits (2205), Expect = 0.0
Identities = 422/542 (77%), Positives = 454/542 (83%), Gaps = 64/542 (11%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA------------------------AKSLLKKP------------ 324
KGAILTTMLATRNFS AKSLL K
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 325 ----------------------------DGVKESTESSNTTIEDEDVKARKQEIIKVTEQ 356
DG+KES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
Query: 357 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 416
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
Query: 417 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 476
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
Query: 477 IK 478
++
Sbjct: 541 LQ 542
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 844 bits (2180), Expect = 0.0
Identities = 422/556 (75%), Positives = 453/556 (81%), Gaps = 78/556 (14%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKK------------------------------------- 323
KGAILTTML +RNFSAAKSLL K
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360
Query: 324 ---PDGVKESTESSNTTIEDEDVKA----------------------------------- 345
DG+K STES NTT EDED+KA
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420
Query: 346 ---RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENA 402
RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN
Sbjct: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480
Query: 403 LSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKW 462
LSK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW
Sbjct: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540
Query: 463 QNVHFHRSGSPTVPIK 478
NVH+H SG+P P++
Sbjct: 541 LNVHYHCSGAPAAPLQ 556
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 829 bits (2142), Expect = 0.0
Identities = 401/478 (83%), Positives = 429/478 (89%), Gaps = 29/478 (6%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
KGAILTTMLATRNFS ARKQEIIK TEQLIEA
Sbjct: 301 KGAILTTMLATRNFS-----------------------------ARKQEIIKTTEQLIEA 331
Query: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH
Sbjct: 332 VNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVH 391
Query: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 392 VIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 795 bits (2053), Expect = 0.0
Identities = 397/518 (76%), Positives = 428/518 (82%), Gaps = 66/518 (12%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA------------------------AKSLLKKP------------ 324
KGAILTTMLATRNFS AKSLL K
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKEPQTTVI 360
Query: 325 ----DGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAF 380
DG+KES++S+NTTIEDED KARKQEIIK TEQLIEA+NNGDFEAY
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA---------- 410
Query: 381 EPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDG 440
FYFEN L+K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG
Sbjct: 411 ----------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 454
Query: 441 SGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 455 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 492
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 612 bits (1579), Expect = e-175
Identities = 312/409 (76%), Positives = 331/409 (80%), Gaps = 64/409 (15%)
Query: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA------------------------AKSLLKKP------------ 324
KGAILTTMLATRNFS AKSLL K
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 325 ----------------------------DGVKESTESSNTTIEDEDVKA 345
DG+KES++S+NTTIEDED KA
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA 409
Score = 246 bits (627), Expect = 4e-65
Identities = 110/134 (82%), Positives = 124/134 (92%)
Query: 345 ARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALS 404
+RKQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+
Sbjct: 533 SRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 592
Query: 405 KSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQN 464
K++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQN
Sbjct: 593 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 652
Query: 465 VHFHRSGSPTVPIK 478
VHFH SG+P P++
Sbjct: 653 VHFHCSGAPVAPLQ 666
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 286 bits (731), Expect = 4e-77
Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ TGQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
++ +CH N I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
AKDL+ +ML ++PA+RIT EAL HPW+ +R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 286 bits (731), Expect = 4e-77
Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ TGQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
++ +CH N I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
AKDL+ +ML ++PA+RIT EAL HPW+ +R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 286 bits (731), Expect = 4e-77
Identities = 146/306 (47%), Positives = 206/306 (67%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E +GKG FSVVRRC+ TGQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKHP+IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
++ +CH N I+HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
AKDL+ +ML ++PA+RIT EAL HPW+ +R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 249 bits (636), Expect = 4e-66
Identities = 142/337 (42%), Positives = 208/337 (61%), Gaps = 10/337 (2%)
Query: 11 TDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
+D +++ ELG+GA S+V RC + T + YA K++ D + + E + L H
Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98
Query: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLN 130
PNI++L + LV +LVTGGELF+ IV + YYSE DA+ ++QILE+V + H N
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 131 GIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDP 190
GIVHRDLKPENLL A+ + A +K+ADFGL+ ++ Q GTPGY +PE+LR
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 191 YGKPVDMWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248
YG VDMW+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AKDL
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 249 INKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTM 308
+ K++ ++P KR+T +AL+HPW+ ++ A+ +H L++FNARRKLK A+ +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334
Query: 309 LATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKA 345
++R SA+ S + K S + S +ED+KA
Sbjct: 335 ASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDMKA 371
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 236 bits (602), Expect = 3e-62
Identities = 133/334 (39%), Positives = 189/334 (56%), Gaps = 9/334 (2%)
Query: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
++ E LG GAFS V + TG+ +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L++V + H GIV
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLA--T 311
+P KR T +A +HPWI + + +H + K F A+ K + A T +
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNATAVVRHM 319
Query: 312 RNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKA 345
R SL D S SS + +D A
Sbjct: 320 RKLHLGSSL----DSSNASVSSSLSLASQKDCLA 349
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 236 bits (601), Expect = 4e-62
Identities = 124/294 (42%), Positives = 177/294 (60%), Gaps = 3/294 (1%)
Query: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
++ E LG GAFS V + TG+ +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L++V + H GIV
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTT 307
+P KR T +A +HPWI + + +H + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 228 bits (581), Expect = 9e-60
Identities = 125/296 (42%), Positives = 175/296 (59%), Gaps = 3/296 (1%)
Query: 12 DEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
D Y + LG GAFS V T + A K I + L ++ +E E + +KHP
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNG 131
NIV L D G YL+ LV+GGELF+ IV + +Y+E DAS I Q+L++V + H G
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 132 IVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY 191
IVHRDLKPENLL S + + + ++DFGL+ +++ GTPGY++PEVL + PY
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251
K VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 252 MLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTT 307
++ +P KR T +AL+HPWI + + +H Q + +KK A+ K K A T
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNAT 310
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 226 bits (576), Expect = 4e-59
Identities = 122/266 (45%), Positives = 162/266 (60%), Gaps = 6/266 (2%)
Query: 8 TRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRL 67
T + E LG GAFS V + TG+ +A K I KK A LE E + +
Sbjct: 17 TNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI--KKSPAFRDSSLENEIAVLKK 74
Query: 68 LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHC 127
+KH NIV L D +YLV LV+GGELF+ I+ R Y+E DAS IQQ+L +V +
Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134
Query: 128 HLNGIVHRDLKPENLLLASKSKGAAVKLADFGLA-IEVQGDQQAWFGFAGTPGYLSPEVL 186
H NGIVHRDLKPENLL + + + + + DFGL+ +E G GTPGY++PEVL
Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMST---ACGTPGYVAPEVL 191
Query: 187 RKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 246
+ PY K VD W+ GVI YILL GYPPF++E + +L+++IK G Y+F SP WD ++ AK
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 247 DLINKMLTINPAKRITASEALKHPWI 272
D I +L +P +R T +AL HPWI
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 224 bits (571), Expect = 1e-58
Identities = 120/260 (46%), Positives = 161/260 (61%), Gaps = 5/260 (1%)
Query: 14 YQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
Y++ E LG GAFS V + + A K I K L ++ +E E + R + HPNI
Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIV 133
V L D YL +LVTGGELF+ I+ R Y+E DASH + Q+L +V++ H GIV
Sbjct: 91 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150
Query: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GTPGYLSPEVLRKDPYG 192
HRDLKPENLL A+ + + + ++DFGL+ G+ G A GTPGY++PE+L + PYG
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207
Query: 193 KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 252
K VD+WA GVI YILL GYPPF+DE L+ QI +Y+F SP WD ++ AKD I +
Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267
Query: 253 LTINPAKRITASEALKHPWI 272
L +P KR T +AL+H WI
Sbjct: 268 LERDPQKRFTCQQALRHLWI 287
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,435,310
Number of Sequences: 37866
Number of extensions: 825779
Number of successful extensions: 4552
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 578
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 2146
Number of HSP's gapped (non-prelim): 1040
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.