BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|26051243 tumor necrosis factor, alpha-induced protein 6 precursor [Homo sapiens] (277 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu... 591 e-169 gi|61743978 stabilin 1 precursor [Homo sapiens] 117 1e-26 gi|61743980 stabilin 2 precursor [Homo sapiens] 107 1e-23 gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 96 3e-20 gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 96 3e-20 gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 96 3e-20 gi|126091152 cubilin [Homo sapiens] 94 2e-19 gi|22547221 tolloid-like 1 [Homo sapiens] 92 6e-19 gi|6912724 tolloid-like 2 [Homo sapiens] 86 5e-17 gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 85 6e-17 gi|13899255 membrane frizzled-related protein [Homo sapiens] 84 1e-16 gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 83 2e-16 gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 83 2e-16 gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 83 2e-16 gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 83 2e-16 gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 83 2e-16 gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 83 2e-16 gi|66864913 neuropilin 1 isoform c [Homo sapiens] 81 9e-16 gi|66912178 neuropilin 1 isoform b [Homo sapiens] 81 9e-16 gi|182508169 neuropilin 1 isoform a [Homo sapiens] 81 9e-16 gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 80 1e-15 gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 78 7e-15 gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sap... 78 1e-14 gi|72384339 CUB domain containing protein 2 [Homo sapiens] 77 2e-14 gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 77 2e-14 gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 76 3e-14 gi|11141887 brain link protein-1 [Homo sapiens] 76 4e-14 gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 75 5e-14 gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 75 5e-14 gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 75 5e-14 >gi|26051243 tumor necrosis factor, alpha-induced protein 6 precursor [Homo sapiens] Length = 277 Score = 591 bits (1524), Expect = e-169 Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLTYAEAKAVCEF 60 MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLTYAEAKAVCEF Sbjct: 1 MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYHREARSGKYKLTYAEAKAVCEF 60 Query: 61 EGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRS 120 EGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRS Sbjct: 61 EGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRS 120 Query: 121 ERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180 ERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF Sbjct: 121 ERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180 Query: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240 Query: 241 QIKYVAMDPVSKSSQGKNTSTTSTGNKNFLAGRFSHL 277 QIKYVAMDPVSKSSQGKNTSTTSTGNKNFLAGRFSHL Sbjct: 241 QIKYVAMDPVSKSSQGKNTSTTSTGNKNFLAGRFSHL 277 >gi|61743978 stabilin 1 precursor [Homo sapiens] Length = 2570 Score = 117 bits (292), Expect = 1e-26 Identities = 50/104 (48%), Positives = 70/104 (67%) Query: 32 ERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGR 91 E+ AGV+H +A SG Y L ++EA+A CE +G LA++ QL AA+++GFH+C GW+A G Sbjct: 2204 EKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGS 2263 Query: 92 VGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKEC 135 +P+V P +CG G+ GI+ G R N SERWDAYC+ C Sbjct: 2264 TAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVAC 2307 >gi|61743980 stabilin 2 precursor [Homo sapiens] Length = 2551 Score = 107 bits (266), Expect = 1e-23 Identities = 46/104 (44%), Positives = 62/104 (59%) Query: 32 ERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGR 91 + GV+H + G+YKLT+ +A+ C E +ATY QL A+K +H+C+AGW+ GR Sbjct: 2194 DTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGR 2253 Query: 92 VGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKEC 135 V YP NCG G GI+DYG R N+SE WD +CY C Sbjct: 2254 VAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMKDVNC 2297 >gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens] Length = 730 Score = 95.9 bits (237), Expect = 3e-20 Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG +SP +P++Y +++C W I++ G + L+F F++E C DY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSKS 253 + D + + +GRYCG E PDDI ST + + LKF+SD S+ GF + + +D S+ Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 254 SQG 256 ++G Sbjct: 555 NRG 557 Score = 75.1 bits (183), Expect = 6e-14 Identities = 39/113 (34%), Positives = 58/113 (51%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG D F SP +PN Y + C W I + G++I L+F DL C DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 + D + GR+CG +LP+ I+ST + + ++F S ++ GF Y A+ Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434 Score = 70.9 bits (172), Expect = 1e-12 Identities = 38/110 (34%), Positives = 54/110 (49%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T SPG+P EY N+ C W + RI L F F+ E + C D+VE Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + G++CG E P+ I S N M ++F SD +V+ GF+ + Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700 >gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo sapiens] Length = 823 Score = 95.9 bits (237), Expect = 3e-20 Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG +SP +P++Y +++C W I++ G + L+F F++E C DY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSKS 253 + D + + +GRYCG E PDDI ST + + LKF+SD S+ GF + + +D S+ Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 254 SQG 256 ++G Sbjct: 555 NRG 557 Score = 75.1 bits (183), Expect = 6e-14 Identities = 39/113 (34%), Positives = 58/113 (51%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG D F SP +PN Y + C W I + G++I L+F DL C DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 + D + GR+CG +LP+ I+ST + + ++F S ++ GF Y A+ Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434 Score = 71.2 bits (173), Expect = 9e-13 Identities = 38/113 (33%), Positives = 56/113 (49%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T SPG+P EY N+ C W + RI L F F+ E + C D+VE Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 + G++CG E P+ I S N M ++F SD +V+ GF+ + ++ Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV 703 >gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo sapiens] Length = 986 Score = 95.9 bits (237), Expect = 3e-20 Identities = 43/123 (34%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG +SP +P++Y +++C W I++ G + L+F F++E C DY+E Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSKS 253 + D + + +GRYCG E PDDI ST + + LKF+SD S+ GF + + +D S+ Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554 Query: 254 SQG 256 ++G Sbjct: 555 NRG 557 Score = 85.5 bits (210), Expect = 5e-17 Identities = 38/110 (34%), Positives = 61/110 (55%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 C T SP +P++Y + C W I G R+ L+F++ D+E P C D++E Sbjct: 747 CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLE 806 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 ++D D +GR+CG + P+ +++TG+ M L+F SD SV GFQ + Sbjct: 807 VFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856 Score = 82.0 bits (201), Expect = 5e-16 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Query: 131 HAKECGGVF---TDPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186 HA ECGG K ++ F N Y C W I + G + L F F++E++ Sbjct: 856 HATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEET 915 Query: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 C DY+E++D YD +GRYCG P+++ S G+ + +KF SD ++T GF ++Y + Sbjct: 916 DCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975 Score = 75.1 bits (183), Expect = 6e-14 Identities = 39/113 (34%), Positives = 58/113 (51%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG D F SP +PN Y + C W I + G++I L+F DL C DYVE Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 + D + GR+CG +LP+ I+ST + + ++F S ++ GF Y A+ Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434 Score = 73.2 bits (178), Expect = 2e-13 Identities = 43/131 (32%), Positives = 62/131 (47%), Gaps = 1/131 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T SPG+P EY N+ C W + RI L F F+ E + C D+VE Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA-MDPVSKS 253 + G++CG E P+ I S N M ++F SD +V+ GF+ + + D SK Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710 Query: 254 SQGKNTSTTST 264 + G +T Sbjct: 711 NGGCQQDCVNT 721 >gi|126091152 cubilin [Homo sapiens] Length = 3623 Score = 93.6 bits (231), Expect = 2e-19 Identities = 48/137 (35%), Positives = 78/137 (56%), Gaps = 3/137 (2%) Query: 134 ECGGVFTDPKQIFKSPGFPN-EYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADY 192 +CGG + +S G P Y DN C WH++ G + +SF DF+L++ GC D+ Sbjct: 2335 QCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDF 2394 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY-VAMDPVS 251 VEI+D++ +GRYCG+ +PD I ++ N ++F++D SVTA GF++++ +M+ Sbjct: 2395 VEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECG 2453 Query: 252 KSSQGKNTSTTSTGNKN 268 QG + TS N Sbjct: 2454 GDLQGSIGTFTSPNYPN 2470 Score = 90.1 bits (222), Expect = 2e-18 Identities = 47/135 (34%), Positives = 68/135 (50%), Gaps = 2/135 (1%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG + T+ +SPG PN Y C WHI ++ IHL F F LE C DY+E Sbjct: 932 CGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 +YD+ D +GRYCG +P + S+GN + L F++D+ + GF I Y A+ + Sbjct: 992 VYDT--DSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISAATACL 1049 Query: 255 QGKNTSTTSTGNKNF 269 Q + + NF Sbjct: 1050 QDYTDDLGTFTSPNF 1064 Score = 89.0 bits (219), Expect = 4e-18 Identities = 46/112 (41%), Positives = 64/112 (57%), Gaps = 2/112 (1%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG F + IF SPG+P+ Y N C W+I G R+ LSF+ F LED C D+VE Sbjct: 1738 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVE 1797 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIIS-TGNVMTLKFLSDASVTAGGFQIKYV 245 I + H VGRYCG+ P + S G+ + ++F+SD S + GFQ ++ Sbjct: 1798 IREGNATGH-LVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFM 1848 Score = 84.0 bits (206), Expect = 1e-16 Identities = 46/114 (40%), Positives = 62/114 (54%), Gaps = 2/114 (1%) Query: 135 CGG-VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYG-QRIHLSFLDFDLEDDPGCLADY 192 CGG + T SP FP Y +NQ C W I+ + I LSF F+LE C D+ Sbjct: 1620 CGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDF 1679 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 VEI D + GRYCG ++P I S + +TL+F+SD+S++AGGF A Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733 Score = 81.6 bits (200), Expect = 7e-16 Identities = 39/110 (35%), Positives = 54/110 (49%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T F SP +P Y + CYW ++ +G L F DF LE P C DY+ Sbjct: 1165 CGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLA 1224 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 +YD + + CGDE P I S+G+ M +K +D GF+ +Y Sbjct: 1225 VYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274 Score = 79.3 bits (194), Expect = 3e-15 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 3/116 (2%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + F SPGFPN Y N+ C W+IR G I L+ DFD+E C D +E Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450 Query: 195 IYDSYDDVHGFVGRYCGDELPDD---IISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 IY D + + C P++ + STGN + ++F +D S+ GF + A+ Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506 Score = 78.2 bits (191), Expect = 7e-15 Identities = 43/119 (36%), Positives = 59/119 (49%), Gaps = 5/119 (4%) Query: 135 CGGVFTDPKQIFKSPGFPNE--YEDNQICYWHIRLKYGQRIHLSFLDFDLE---DDPGCL 189 CGG T F SP + Y+ N C W I + IHL+F F LE CL Sbjct: 3157 CGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCL 3216 Query: 190 ADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248 DYV++YD + G +CG +P IS+GN +T++F+SD ++ GF Y MD Sbjct: 3217 YDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIMD 3275 Score = 74.3 bits (181), Expect = 1e-13 Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG+F P SP +P+ Y N C W IR+ R+ L+F DFDLE C + Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IM 1565 Query: 195 IYDSYDDVHGFVGRYCG-DELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 YD + R CG ++L + I+S+GN + L+F S S GF+ ++ Sbjct: 1566 AYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616 Score = 73.6 bits (179), Expect = 2e-13 Identities = 43/122 (35%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Query: 128 YNPHAKECGGVF----TDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLD-FDL 182 Y + CGG D SP P+ Y + C W + RI L F D FD+ Sbjct: 2210 YEAKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDI 2269 Query: 183 EDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQI 242 E P C ++Y+E+ D D + ++CG LP S+G VM L+F SD S T GF+ Sbjct: 2270 EVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKA 2329 Query: 243 KY 244 KY Sbjct: 2330 KY 2331 Score = 71.2 bits (173), Expect = 9e-13 Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 5/101 (4%) Query: 145 IFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHG 204 I +S G+PN Y +NQ C W IR G ++ +FL FDLE C DY+E+YD Sbjct: 1290 ILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ--- 1346 Query: 205 FVGRYCGDELPDDIISTGNVMTLKFLSD-ASVTAGGFQIKY 244 +GRYCG +LP +T + + + L+D GFQ+++ Sbjct: 1347 -MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQW 1386 Score = 70.5 bits (171), Expect = 2e-12 Identities = 47/133 (35%), Positives = 65/133 (48%), Gaps = 5/133 (3%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPG-CLA 190 A C +TD F SP FPN Y +N C + I ++ GQ I + F +F LE+ G Sbjct: 1045 ATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYT 1104 Query: 191 DYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPV 250 D++EI D + +G + G LP IIS N + LKF SD T GF + Sbjct: 1105 DFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDG---- 1160 Query: 251 SKSSQGKNTSTTS 263 S + G N +T+S Sbjct: 1161 SSTGCGGNLTTSS 1173 Score = 70.1 bits (170), Expect = 2e-12 Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 1/111 (0%) Query: 135 CGGVFTDPKQIFKSPGFPN-EYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 CGGVF I SP + +Y ++ C + I + + I L F DFD+ C DY+ Sbjct: 3037 CGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYL 3096 Query: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 IYD + +G++CG + P ++ S+ N M L F +D+ TA G+++ + Sbjct: 3097 AIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSF 3147 Score = 68.9 bits (167), Expect = 4e-12 Identities = 38/114 (33%), Positives = 54/114 (47%), Gaps = 4/114 (3%) Query: 131 HAK----ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186 HAK +CGG+ + SP +PN Y+ C + G I L+F DFD+E Sbjct: 2681 HAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHT 2740 Query: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240 C D V + + +G+YCG+ P I S N + + F SD S+ GGF Sbjct: 2741 TCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGF 2794 Score = 65.1 bits (157), Expect = 6e-11 Identities = 41/143 (28%), Positives = 60/143 (41%), Gaps = 1/143 (0%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 ECGG+ T P KSPG+P Y + C W + + +F LE C DY+ Sbjct: 589 ECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYL 648 Query: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKS 253 EI D +G++C + +TG + F SD+ ++ GF I Y+ P Sbjct: 649 EIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLT-SPSDLR 707 Query: 254 SQGKNTSTTSTGNKNFLAGRFSH 276 G T L+G F+H Sbjct: 708 CGGNYTDPEGELFLPELSGPFTH 730 Score = 65.1 bits (157), Expect = 6e-11 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 1/101 (0%) Query: 148 SPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHGFVG 207 SP +P Y N W + + +H L+ D+E+ C D + IYD +G Sbjct: 1865 SPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIG 1924 Query: 208 RYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248 YCG + + STGN +T F SD+S++ GF +++ A+D Sbjct: 1925 AYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVD 1964 Score = 64.3 bits (155), Expect = 1e-10 Identities = 40/144 (27%), Positives = 65/144 (45%), Gaps = 7/144 (4%) Query: 133 KECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADY 192 +ECGG F SP +PN +IC W I G+RI L F + L P C ++ Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509 Query: 193 VEIYDSYDDVHGFVGRYCGD-ELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD--- 248 V +++ + + C + ++I S+GN M + F +D S GGF Y + + Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAV 2569 Query: 249 ---PVSKSSQGKNTSTTSTGNKNF 269 + + +G TS G +N+ Sbjct: 2570 CGGSLPNTPEGNFTSPGYDGVRNY 2593 Score = 63.9 bits (154), Expect = 1e-10 Identities = 37/112 (33%), Positives = 54/112 (48%), Gaps = 3/112 (2%) Query: 135 CGGVFT--DPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADY 192 CGG D SPG+P+ Y + C W I+ + L+ L D+E C D Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 2036 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + I D +++ + CG E+P I STG M ++F SD+SVT GF + Sbjct: 2037 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088 Score = 63.5 bits (153), Expect = 2e-10 Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 2/135 (1%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG T + + +SP FPN Y + C W I Q I L+F F++ C DYVE Sbjct: 817 CGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 I S +YCG ++P I S N + + F+ +S GF K+ A D Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935 Query: 255 QGKNTST-TSTGNKN 268 ++T T S G+ N Sbjct: 936 LTESTGTIQSPGHPN 950 Score = 59.7 bits (143), Expect = 3e-09 Identities = 34/136 (25%), Positives = 69/136 (50%), Gaps = 9/136 (6%) Query: 107 KTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIR 166 K+G+++ R++ + + A C + K G + +SPG+P+ Y++++ C + Sbjct: 3376 KSGVVNRNSRMSFTYQI-ADCNRDYHKAFGNL--------RSPGWPDNYDNDKDCTVTLT 3426 Query: 167 LKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMT 226 I L F +E+ C D++E+ + + +G+YCG LP+ + S N + Sbjct: 3427 APQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELY 3486 Query: 227 LKFLSDASVTAGGFQI 242 L+F SD+ + G++I Sbjct: 3487 LRFKSDSVTSDRGYEI 3502 Score = 59.7 bits (143), Expect = 3e-09 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + F SPG+P Y +N C W + G+ + ++F ++D C+ +Y+ Sbjct: 3511 CGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570 Query: 195 IYDSYDDVHGFVGRYC-GDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 +YD + G YC GD +++ N + +KF +D + F++ + Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTW 3621 Score = 58.5 bits (140), Expect = 6e-09 Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 5/114 (4%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLED----DPGCLA 190 CG FT P SP +P +Y++N C + I + L+F+ F LE C+ Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979 Query: 191 DYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 D V I Y + CGDE+P + G V+ L F S+ +T GF+ Y Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSY 3032 Score = 58.2 bits (139), Expect = 8e-09 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 9/123 (7%) Query: 133 KECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSF-LDFDLED-DPGC-L 189 K CGG + I SP +P Y N C WH+ ++ G I + F F + + D C Sbjct: 2090 KSCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQ 2149 Query: 190 ADYVEIYDSYD------DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIK 243 DY+ + + D G G +CG + ++ N M ++F+SD S GF+IK Sbjct: 2150 GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIK 2209 Query: 244 YVA 246 Y A Sbjct: 2210 YEA 2212 Score = 57.0 bits (136), Expect = 2e-08 Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 2/104 (1%) Query: 146 FKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDDVHGF 205 ++SP ++ N C+W I+ + G+ + ++F F LE C +++++YD Sbjct: 487 YRSPDVGYVHDVN--CFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQ 544 Query: 206 VGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDP 249 +GR+CG LP +++S+ N + S+ GF +++ P Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 588 Score = 52.8 bits (125), Expect = 3e-07 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Query: 126 YCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD 185 Y +P CGG +TDP+ P + + C + ++ G++I ++F +L+ Sbjct: 699 YLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQ 758 Query: 186 PGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 +Y+E+ D +G+ CG+ I S N + ++F DASV F+ Y Sbjct: 759 SDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813 Score = 48.5 bits (114), Expect = 6e-06 Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 4/122 (3%) Query: 128 YNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDL--EDD 185 +N CGG+F +SP +P + +N C W + + +SF + L D Sbjct: 2798 WNTQTLGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGD 2857 Query: 186 PGCLADYVEIYDSYDDV-HGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C +V+++ ++V + CG+ P +I+ N T F S A GF + Sbjct: 2858 GQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF 2916 Query: 245 VA 246 V+ Sbjct: 2917 VS 2918 >gi|22547221 tolloid-like 1 [Homo sapiens] Length = 1013 Score = 91.7 bits (226), Expect = 6e-19 Identities = 40/108 (37%), Positives = 64/108 (59%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 EC P + SP +P++Y + C W I G RI L+F +F++E C D++ Sbjct: 773 ECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHL 832 Query: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQ 241 E++D + +GR CG+++PD +++TGN M ++F+SDASV GFQ Sbjct: 833 EVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQ 880 Score = 83.6 bits (205), Expect = 2e-16 Identities = 36/110 (32%), Positives = 59/110 (53%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + +SP +P++Y + C W I + + L+F F++E C DY+E Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + D + +GR+CG + P+DI ST N + +KF+SD +V GF + Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571 Score = 80.1 bits (196), Expect = 2e-15 Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG+ T +PG+P EY N+ C W + RI + F F+LE + C DYVE Sbjct: 618 CGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVE 677 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA-MDPVSKS 253 I+ G++CG E+P+ I S N M ++F SD +V+ GF+ + + D SK Sbjct: 678 IWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKD 737 Query: 254 SQG 256 + G Sbjct: 738 NGG 740 Score = 79.3 bits (194), Expect = 3e-15 Identities = 39/113 (34%), Positives = 58/113 (51%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG + SPGFPN Y C W + + G++I L+F DL C DY+E Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAM 247 + D Y +GR+CGD+LP+ + ST + M ++F S ++ GF Y A+ Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461 Score = 78.6 bits (192), Expect = 6e-15 Identities = 39/118 (33%), Positives = 64/118 (54%), Gaps = 4/118 (3%) Query: 131 HAKECGGVF---TDPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186 H+ ECGG + P+ ++ F N Y C W + + G R+ LSF F++E++ Sbjct: 883 HSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEA 942 Query: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C DYVE++D D +GR+CG P++I S G+ + + F +D ++ GF I+Y Sbjct: 943 DCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000 >gi|6912724 tolloid-like 2 [Homo sapiens] Length = 1015 Score = 85.5 bits (210), Expect = 5e-17 Identities = 38/107 (35%), Positives = 62/107 (57%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 C + + SP +P++Y + C W+I G R+ L+F +F++E C D++E Sbjct: 776 CAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLE 835 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQ 241 +YD D + +GR+CG + PD +++G+ M L+F SDASV GFQ Sbjct: 836 MYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882 Score = 83.2 bits (204), Expect = 2e-16 Identities = 40/112 (35%), Positives = 60/112 (53%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG D F +PGFPN Y C W I + G++I L+F DL C DYVE Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 + D Y +GR+CGD++P+ ++ST + + ++F S +++ GF Y A Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462 Score = 82.8 bits (203), Expect = 3e-16 Identities = 35/110 (31%), Positives = 59/110 (53%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG +SP +P++Y ++ C W I + G + L+F F++E C DY+E Sbjct: 464 CGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLE 523 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + D + +G +CG E P+D+ S+ N + +KF+SD S+ GF + Sbjct: 524 VRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573 Score = 77.8 bits (190), Expect = 1e-14 Identities = 43/123 (34%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T SPG+P EY N+ C W + RI L F F+LE + C D+VE Sbjct: 620 CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA-MDPVSKS 253 + GR+CG E P+ I S N M ++F SD +V+ GF+ + + D +K Sbjct: 680 VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKD 739 Query: 254 SQG 256 + G Sbjct: 740 NGG 742 Score = 73.6 bits (179), Expect = 2e-13 Identities = 37/120 (30%), Positives = 62/120 (51%), Gaps = 4/120 (3%) Query: 131 HAKECGGVF---TDPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186 H+ ECGG K+++ F N Y C W I + G + L+F F++E++ Sbjct: 885 HSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEA 944 Query: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 C DY+E YD YD +GR+CG ++I S G+ + ++F +D ++ GF +Y + Sbjct: 945 DCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004 >gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] Length = 415 Score = 85.1 bits (209), Expect = 6e-17 Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG+ T S GFP Y N C W I + G+ + L+F DLE D C D+V+ Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 +Y+ + + +GR+CG P ++S+GN M ++ +SDA+ GF + A +P + Sbjct: 93 VYNGHANGQR-IGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151 Query: 255 Q 255 Q Sbjct: 152 Q 152 Score = 84.3 bits (207), Expect = 1e-16 Identities = 55/158 (34%), Positives = 77/158 (48%), Gaps = 15/158 (9%) Query: 120 SERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPN-EYEDNQICYWHIRLKYGQRIHLSFL 178 +ER D YC GG+ P FK+P +P+ +Y C WHI Q I L F Sbjct: 147 NERGDQYC--------GGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFE 198 Query: 179 DFDLEDDPGCLADYVEIYDS--YDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVT 236 FD+E D C DYV +++ +D +G+YCGD P I+S N + ++FLSD S+T Sbjct: 199 KFDVERDNYCRYDYVAVFNGGEVNDARR-IGKYCGDSPPAPIVSERNELLIQFLSDLSLT 257 Query: 237 AGGFQIKYVAMD---PVSKSSQGKNTSTTSTGNKNFLA 271 A GF Y+ P + T +TG K +A Sbjct: 258 ADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVA 295 >gi|13899255 membrane frizzled-related protein [Homo sapiens] Length = 579 Score = 84.0 bits (206), Expect = 1e-16 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 1/134 (0%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T + F +P + +Y +C WHI + G I L F +F LE C DYVE Sbjct: 301 CGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVE 360 Query: 195 IYD-SYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKS 253 +Y+ S +GR+CG E P ++S+ + + + F +D +++GGF Y+A + Sbjct: 361 VYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENP 420 Query: 254 SQGKNTSTTSTGNK 267 S + G K Sbjct: 421 CGPSELSCQAGGCK 434 Score = 68.6 bits (166), Expect = 6e-12 Identities = 37/115 (32%), Positives = 56/115 (48%), Gaps = 3/115 (2%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG+ + P+ F SP +P+ Y N C WHI++ I L +E CL D +E Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDP 249 + + G + R CG P + + + + + F+SD+SV GF Y AM P Sbjct: 204 L---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAP 255 >gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] Length = 909 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] Length = 901 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] Length = 931 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] Length = 555 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] Length = 906 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] Length = 926 Score = 83.2 bits (204), Expect = 2e-16 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 6/119 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP----- 186 +++C FT P +SPGFP +Y N C + I K I L FL FDLE DP Sbjct: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205 Query: 187 -GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D+++I+D V +G+YCG + P ++ S+ +++L F +D +V GF +Y Sbjct: 206 GDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264 Score = 66.2 bits (160), Expect = 3e-11 Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 2/132 (1%) Query: 135 CGGVFTDPKQIF-KSPGFPNEYEDNQICYWHIRL-KYGQRIHLSFLDFDLEDDPGCLADY 192 CGG + SPG+P +Y +Q C W + + Q+I L+F + C D+ Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 +EI D + +G++CG+ P IIS+G+++ +KF SD + GF ++Y S+ Sbjct: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147 Query: 253 SSQGKNTSTTST 264 TS T Sbjct: 148 DCSKNFTSPNGT 159 >gi|66864913 neuropilin 1 isoform c [Homo sapiens] Length = 609 Score = 81.3 bits (199), Expect = 9e-16 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 6/117 (5%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD---PG--- 187 EC +T P + KSPGFP +Y ++ C + + I L F FDLE D PG Sbjct: 146 ECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205 Query: 188 CLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D +EI+D + DV +GRYCG + P I S+ ++++ F +D+++ GF Y Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262 Score = 72.0 bits (175), Expect = 5e-13 Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 3/114 (2%) Query: 148 SPGFPNEYEDNQICYWHIRLKYG-QRIHLSFLD-FDLEDDPGCLADYVEIYDSYDDVHGF 205 SPG+P+ Y ++ C W I+ QRI ++F FDLED C DYVE++D ++ F Sbjct: 41 SPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHF 99 Query: 206 VGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSSQGKNT 259 G++CG P ++S+G + +KF+SD GF I+Y + SQ T Sbjct: 100 RGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTT 153 >gi|66912178 neuropilin 1 isoform b [Homo sapiens] Length = 644 Score = 81.3 bits (199), Expect = 9e-16 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 6/117 (5%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD---PG--- 187 EC +T P + KSPGFP +Y ++ C + + I L F FDLE D PG Sbjct: 146 ECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205 Query: 188 CLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D +EI+D + DV +GRYCG + P I S+ ++++ F +D+++ GF Y Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262 Score = 72.0 bits (175), Expect = 5e-13 Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 3/114 (2%) Query: 148 SPGFPNEYEDNQICYWHIRLKYG-QRIHLSFLD-FDLEDDPGCLADYVEIYDSYDDVHGF 205 SPG+P+ Y ++ C W I+ QRI ++F FDLED C DYVE++D ++ F Sbjct: 41 SPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHF 99 Query: 206 VGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSSQGKNT 259 G++CG P ++S+G + +KF+SD GF I+Y + SQ T Sbjct: 100 RGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTT 153 >gi|182508169 neuropilin 1 isoform a [Homo sapiens] Length = 923 Score = 81.3 bits (199), Expect = 9e-16 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 6/117 (5%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD---PG--- 187 EC +T P + KSPGFP +Y ++ C + + I L F FDLE D PG Sbjct: 146 ECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205 Query: 188 CLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 C D +EI+D + DV +GRYCG + P I S+ ++++ F +D+++ GF Y Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262 Score = 72.0 bits (175), Expect = 5e-13 Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 3/114 (2%) Query: 148 SPGFPNEYEDNQICYWHIRLKYG-QRIHLSFLD-FDLEDDPGCLADYVEIYDSYDDVHGF 205 SPG+P+ Y ++ C W I+ QRI ++F FDLED C DYVE++D ++ F Sbjct: 41 SPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHF 99 Query: 206 VGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSSQGKNT 259 G++CG P ++S+G + +KF+SD GF I+Y + SQ T Sbjct: 100 RGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTT 153 >gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] Length = 3487 Score = 80.5 bits (197), Expect = 1e-15 Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 4/111 (3%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 +CGG + + + SPGFP Y N C W I L G H+ FL+F E + DY+ Sbjct: 1967 QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYI 2022 Query: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 EI + + +GR+ G ELP ++ST + T+ F SD S GF+++Y Sbjct: 2023 EIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073 Score = 74.3 bits (181), Expect = 1e-13 Identities = 46/132 (34%), Positives = 63/132 (47%), Gaps = 4/132 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T P + SP +P Y + C W + + I L F F+LE PG D++ Sbjct: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLE--PGY--DFLH 1500 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 IYD D + +G + G +LP I S+ N + L F SDASV+ GF I Y S Sbjct: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560 Query: 255 QGKNTSTTSTGN 266 G + T G+ Sbjct: 1561 PGSIKNGTRVGS 1572 Score = 68.9 bits (167), Expect = 4e-12 Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 4/133 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T+ + SPGFP Y ++ C W I + G I + + F E + D +E Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLE 1851 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 ++D D+ +G + G +P + ST N + L F SD SV+A GF ++Y + S Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPE 1911 Query: 255 QGKNTSTTSTGNK 267 ++ TG + Sbjct: 1912 PAVPSNGVKTGER 1924 Score = 67.8 bits (164), Expect = 1e-11 Identities = 45/138 (32%), Positives = 62/138 (44%), Gaps = 9/138 (6%) Query: 120 SERWDAYCYNPHAKE-CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFL 178 S WD + A + CGG I SP FP+EY +N C W I + G I L F+ Sbjct: 186 SATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFI 245 Query: 179 DFDLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAG 238 DF LED D++E+ G + G LP +IS+ N + L F SD + Sbjct: 246 DFQLEDG----YDFLEV----TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQR 297 Query: 239 GFQIKYVAMDPVSKSSQG 256 GF +Y + S+G Sbjct: 298 GFSAQYQVKKQIELKSRG 315 Score = 66.2 bits (160), Expect = 3e-11 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 4/106 (3%) Query: 139 FTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDS 198 FT P + SP +P +Y ++ C W I + RIHL+F D D+E D++ I D Sbjct: 582 FTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDG 637 Query: 199 YDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 +G + G++LP I S+G+V L+F +D S GF I + Sbjct: 638 ATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITF 683 Score = 64.7 bits (156), Expect = 8e-11 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 6/138 (4%) Query: 122 RWDAYCYNPHA--KECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLD 179 RW ++P + + C P +SPGFP Y + C W I + RI L F Sbjct: 11 RWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQS 70 Query: 180 FDLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGG 239 F LE+D D + ++D R G +LP I+S ++L+ +SD +V+A G Sbjct: 71 FALEED----FDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQG 126 Query: 240 FQIKYVAMDPVSKSSQGK 257 F Y + + + G+ Sbjct: 127 FHATYEVLPSHTCGNPGR 144 Score = 63.5 bits (153), Expect = 2e-10 Identities = 38/110 (34%), Positives = 55/110 (50%), Gaps = 4/110 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T P SPG+P Y+D C W I + G I ++F F E + D +E Sbjct: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLE 807 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + D +G Y G ++P +IST N + L F +D S + GFQ++Y Sbjct: 808 VRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRY 857 Score = 59.7 bits (143), Expect = 3e-09 Identities = 54/187 (28%), Positives = 78/187 (41%), Gaps = 16/187 (8%) Query: 91 RVGYPIVKPGPNCGFGKTGIIDYGIRLNRSER----------WDAYCYNPHAKECGG-VF 139 + GY + G G + D G L SE WD A ECGG V Sbjct: 1218 KFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA-ECGGTVR 1276 Query: 140 TDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSY 199 + SPG+P YE N C W I + G I L FL FD E+ + D + I+D Sbjct: 1277 GEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHDVLRIWDGP 1332 Query: 200 DDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSSQGKNT 259 + + G LP D+ ST N + L+F +D + GF I++ S + G Sbjct: 1333 VESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ 1392 Query: 260 STTSTGN 266 + + +G+ Sbjct: 1393 NGSRSGD 1399 Score = 53.9 bits (128), Expect = 1e-07 Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 7/128 (5%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHI-RLKYGQRIHLSFLDFDLEDDPGCLA 190 A+ C P I SP FP +Y++N C W I L + I L+F +FDLE Sbjct: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG----Y 457 Query: 191 DYVEIYDSYDDVHGFVGRY--CGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248 D + + D D Y G +PD I+ST + M L F +D S ++ GF+ Y ++ Sbjct: 458 DTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIE 517 Query: 249 PVSKSSQG 256 S G Sbjct: 518 QGSCGDPG 525 Score = 53.5 bits (127), Expect = 2e-07 Identities = 32/124 (25%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 ECG T + SP FP Y +N C + I+ + G+ I L F+L + D + Sbjct: 1097 ECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSE-----GDVL 1151 Query: 194 EIYDSYDDVHGFVGRYCGDELPD-DIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 ++YD ++ +G + E+ + ST + + L F++DA T+ GF++ + + + + Sbjct: 1152 KVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKC 1211 Query: 253 SSQG 256 G Sbjct: 1212 EDPG 1215 Score = 51.2 bits (121), Expect = 1e-06 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 10/120 (8%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIR--LKYGQRIHLSFLDFDLEDDPGCLADY 192 CGG T SPGFP+ Y +Q C W I + +G R++LS L+ +P D+ Sbjct: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSL----LQTEPS--GDF 2235 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 + I+D +G + + S+ N + LKF DA+ T G F I + A P++K Sbjct: 2236 ITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA-TGGIFAIAFSAY-PLTK 2293 Score = 47.4 bits (111), Expect = 1e-05 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 12/121 (9%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + + SP +P Y QIC + + + + F F L D VE Sbjct: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHT-----ALNDVVE 1673 Query: 195 IYDSYDD----VHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPV 250 ++D + + G + G+ LP ++T N + +KF + A GF Y A+ Sbjct: 1674 VHDGHSQHSRLLSSLSGSHTGESLP---LATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 1730 Query: 251 S 251 S Sbjct: 1731 S 1731 Score = 46.6 bits (109), Expect = 2e-05 Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 8/117 (6%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG SPGFP+ Y +N C W I +G+ + +F F LE DY+ Sbjct: 924 CGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESG----HDYLL 979 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIIS--TGN-VMTLKFLSDASVTAGGFQIKYVAMD 248 I ++ + + G LP I + GN ++F+SD S++ GF I + D Sbjct: 980 ITENGSFTQP-LRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYD 1035 Score = 38.1 bits (87), Expect = 0.008 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 5/110 (4%) Query: 138 VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYD 197 + TD + S +P Y Q C W +R++ I L+ F E D EI+D Sbjct: 2360 LLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ----YDEFEIFD 2415 Query: 198 SYDDVHGFVGRYCGD-ELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 + G+ P + S+ N + L++ SD + GF+I+Y A Sbjct: 2416 GPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465 >gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sapiens] Length = 775 Score = 78.2 bits (191), Expect = 7e-15 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 3/117 (2%) Query: 135 CGGVFTDPKQ-IFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 CG P+ S +P Y ++ +C W IR+K G+R+ + F DFD+ED C +Y+ Sbjct: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131 Query: 194 EIYDSYDDVHGFVGRYC--GDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248 IY+ +G+YC G ++ I S GN +TL F+S V+ GF Y +D Sbjct: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVID 188 >gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sapiens] Length = 402 Score = 77.8 bits (190), Expect = 1e-14 Identities = 45/110 (40%), Positives = 60/110 (54%), Gaps = 14/110 (12%) Query: 31 LERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKG 90 LE YH R G+YKLT+AEA+ C + G LA+ +QL AA + G C AGW+ G Sbjct: 160 LEGVVFPYH--PRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDG 217 Query: 91 RVGYPIVKPGPNC-GFGKT-----------GIIDYGIRLNRSERWDAYCY 128 V YP+ +P C G G T G+ +YG R N ER+DA+C+ Sbjct: 218 SVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCF 267 Score = 47.8 bits (112), Expect = 1e-05 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%) Query: 51 YAEAKAVCEFEGGHLATYKQLEAARKIGF-HVCAAGWMAKGRVGYPIVKPGPNCGFGKTG 109 ++ A C G +A QL AA K+ C AGW+A G YPIV P CG + G Sbjct: 286 FSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGGRRPG 345 Query: 110 IIDYGIRLNRSERWDAYCY 128 + G + YCY Sbjct: 346 VRSLGFPDATRRLFGVYCY 364 >gi|72384339 CUB domain containing protein 2 [Homo sapiens] Length = 449 Score = 77.0 bits (188), Expect = 2e-14 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 +CGGV + P F SP FP Y N C W I + G + L+F FDLE C D++ Sbjct: 29 KCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFL 88 Query: 194 EIYD-SYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 EIY+ + D +GR+CG P S+ +VM++ F SD V + GF Y Sbjct: 89 EIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGY 140 Score = 75.1 bits (183), Expect = 6e-14 Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 4/116 (3%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPG----CL 189 EC V+ + F SP +P+ Y +N C+W IRL G ++ + FLD DLE+ C Sbjct: 256 ECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCD 315 Query: 190 ADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV 245 D++ +D + +G +CG LP + S+ N + L +D S T GF + Y+ Sbjct: 316 FDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYI 371 Score = 73.2 bits (178), Expect = 2e-13 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGGV T + SP +PN Y ++ C+W IR + L F+DF +E + C DYV Sbjct: 145 CGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVA 204 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + G YCG P ++S G+ + + F SD ++ GF+ Y Sbjct: 205 VLGGPGPTRGH--HYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY 252 >gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] Length = 449 Score = 76.6 bits (187), Expect = 2e-14 Identities = 45/125 (36%), Positives = 65/125 (52%), Gaps = 3/125 (2%) Query: 135 CGGVFTDPKQIFKSPGFP-NEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 CGG + +P +P ++Y C WHI Q I L+F FDLE D C D V Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSV 218 Query: 194 EIYD-SYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD-PVS 251 +++ + D +G++CGD +P I S GN + ++F+SD SVTA GF Y + + Sbjct: 219 SVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTA 278 Query: 252 KSSQG 256 K QG Sbjct: 279 KEGQG 283 Score = 75.1 bits (183), Expect = 6e-14 Identities = 39/110 (35%), Positives = 54/110 (49%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG S GFPN Y N+ C W I + GQ + LSF FDLE P C D +E Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 ++ +GR+CG P +++ GN +TL+ +D GF + Y Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146 >gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] Length = 3565 Score = 76.3 bits (186), Expect = 3e-14 Identities = 42/112 (37%), Positives = 59/112 (52%), Gaps = 4/112 (3%) Query: 133 KECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADY 192 + CGG+ P +SPGFP+ Y + C W I RI LSF F LE+D D Sbjct: 30 QNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEED----FDI 85 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 + +YD R G +LP I+STG+++TL F +D +V+A GF+ Y Sbjct: 86 LSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137 Score = 74.3 bits (181), Expect = 1e-13 Identities = 40/106 (37%), Positives = 57/106 (53%), Gaps = 4/106 (3%) Query: 139 FTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDS 198 FT I SP +P EY +N C W I + G RIHL F DFD+E D++ + D Sbjct: 589 FTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDD 644 Query: 199 YDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 +G + G+E+P + S+G+++ L+F SD S T GF I Y Sbjct: 645 GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITY 690 Score = 72.0 bits (175), Expect = 5e-13 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 4/110 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T P + SP +P Y + C W +++ I L F F++E D++ Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPS----YDFLH 1507 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 IY+ D +G Y G + P+ I S+GN + L F SDASV GF I++ Sbjct: 1508 IYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF 1557 Score = 70.5 bits (171), Expect = 2e-12 Identities = 37/114 (32%), Positives = 57/114 (50%), Gaps = 4/114 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + + SPGFP Y +N C W I L G H+ FL+F E + D++E Sbjct: 1975 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN----HDFLE 2030 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMD 248 I + +G++ G +LP ++ST + + F SD S GF++ Y A + Sbjct: 2031 IQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYE 2084 Score = 66.6 bits (161), Expect = 2e-11 Identities = 38/110 (34%), Positives = 54/110 (49%), Gaps = 4/110 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 C G FT + SPG+P Y +N C W I + G I + + F E + D +E Sbjct: 1803 CSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLE 1858 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 I+D D +G + G +P + ST N + L F SD SV A GF ++Y Sbjct: 1859 IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEY 1908 Score = 66.2 bits (160), Expect = 3e-11 Identities = 41/119 (34%), Positives = 58/119 (48%), Gaps = 4/119 (3%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG T + PG+P Y+D+ C W I K G I ++F F E + D +E Sbjct: 759 CGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVN----YDTLE 814 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKS 253 + D +G Y G + P +ISTGN M L F +D S ++ GF I Y ++ S S Sbjct: 815 VRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDS 873 Score = 65.9 bits (159), Expect = 4e-11 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 5/134 (3%) Query: 134 ECGG-VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADY 192 ECGG + SPG+P Y++N C W I G+ I L F+ FD E D Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDI 1332 Query: 193 VEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 ++++D D + + G LP+DI ST N +TL+F SD ++ GF I++ + Sbjct: 1333 LKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATC 1392 Query: 253 SSQGKNTSTTSTGN 266 + G + T G+ Sbjct: 1393 NDPGMPQNGTRYGD 1406 Score = 61.6 bits (148), Expect = 7e-10 Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 8/132 (6%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG SP FP+EYE+N C W I + G I L F DF LE+ D++E Sbjct: 208 CGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG----YDFLE 263 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVSKSS 254 I + G LP +IS+ N + L F SD++ GF ++ + S Sbjct: 264 ISGTEAPSIWLTGM----NLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS 319 Query: 255 QGKNTSTTSTGN 266 +G + G+ Sbjct: 320 RGVKMLPSKDGS 331 Score = 60.5 bits (145), Expect = 2e-09 Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Query: 134 ECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193 ECG + SP FP+ Y++N C + I + G+ IHL F L + D + Sbjct: 1104 ECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFE-----GDTL 1158 Query: 194 EIYDSYDDVHGFVGRYCGDELPDDII-STGNVMTLKFLSDASVTAGGFQIKYVAMDPVSK 252 ++YD D +G + +EL I+ ST N + L+F ++ S T GFQ+ Y + D V Sbjct: 1159 KVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKC 1218 Query: 253 SSQG 256 G Sbjct: 1219 EDPG 1222 Score = 56.2 bits (134), Expect = 3e-08 Identities = 43/142 (30%), Positives = 61/142 (42%), Gaps = 4/142 (2%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQR-IHLSFLDFDLEDDPGCLA 190 A+ CG P + SP +P +YEDN C W I + I L+F +F+LE L Sbjct: 409 ARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLT 468 Query: 191 DYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPV 250 V D + G +PD I+S N M L SD S+ + GF+ Y ++ Sbjct: 469 --VGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKG 526 Query: 251 SKSSQGKNTSTTSTGNKNFLAG 272 G TG+ +FL G Sbjct: 527 GCGDPGIPAYGKRTGS-SFLHG 547 Score = 51.2 bits (121), Expect = 1e-06 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 13/152 (8%) Query: 102 NCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGFPNEYEDNQIC 161 +C G T D + R+ +W+ + A CGG SPGFP+ Y ++ C Sbjct: 899 SCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSPGFPDFYPNSLNC 957 Query: 162 YWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYD--SYDDVHGFVGRYCGDELPDDII 219 W I + +G+ + + F F LE DY+ I + S+ + V R G LP I Sbjct: 958 TWTIEVSHGKGVQMIFHTFHLESS----HDYLLITEDGSFSEP---VARLTGSVLPHTIK 1010 Query: 220 S--TGN-VMTLKFLSDASVTAGGFQIKYVAMD 248 + GN L+F+SD S++ GF I + D Sbjct: 1011 AGLFGNFTAQLRFISDFSISYEGFNITFSEYD 1042 Score = 50.4 bits (119), Expect = 2e-06 Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 6/106 (5%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CG T SPGFP+EY + C W I + G ++++F E + DY+ Sbjct: 2147 CGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVNDYIA 2202 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240 ++D D +G + G+ + S+ N + LKF SD S GGF Sbjct: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS--NGGF 2246 Score = 47.8 bits (112), Expect = 1e-05 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 24/164 (14%) Query: 93 GYPIVKPGP-NCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGF 151 GY I+ P C G G WD + +A CGG +T + + SP + Sbjct: 1594 GYKILDPSSITCVIGADG----------KPSWDQVLPSCNAP-CGGQYTGSEGVVLSPNY 1642 Query: 152 PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYDSYDD----VHGFVG 207 P+ Y QIC + I + + F F L D E++D + G Sbjct: 1643 PHNYTAGQICLYSITVPKEFVVFGQFAYFQT-----ALNDLAELFDGTHAQARLLSSLSG 1697 Query: 208 RYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVAMDPVS 251 + G+ LP ++T N + L+F + + +A GF Y A+ S Sbjct: 1698 SHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQAVPRTS 1738 Score = 40.8 bits (94), Expect = 0.001 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 5/110 (4%) Query: 138 VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVEIYD 197 V T + SPG+P Y ++Q C W I+++ I + F E D +E++D Sbjct: 2325 VRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ----FDALEVFD 2380 Query: 198 SYDDVHGFVGRYCGDEL-PDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246 + G+ + S N + L++ +D + + GF+I+Y A Sbjct: 2381 GSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2430 >gi|11141887 brain link protein-1 [Homo sapiens] Length = 340 Score = 75.9 bits (185), Expect = 4e-14 Identities = 42/110 (38%), Positives = 59/110 (53%), Gaps = 3/110 (2%) Query: 37 VYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGRVGYPI 96 V+ + G+Y+ Y EAK CE + G LATY QL A G C AGW+ +G V YP+ Sbjct: 149 VFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPV 208 Query: 97 VKPGPNC-GFGKTGIIDYGIRLNRSERWDAYCYNPHAKECGGVFTDPKQI 145 + C G G+ GI YG R +R+DA+C+ + G VF P ++ Sbjct: 209 LTARAPCGGRGRPGIRSYGPRDRMRDRYDAFCFT--SALAGQVFFVPGRL 256 Score = 53.9 bits (128), Expect = 1e-07 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 48 KLTYAEAKAVCEFEGGHLATYKQLEAARKI-GFHVCAAGWMAKGRVGYPIVKPGPNC-GF 105 +LT +EA A C G +A L AA K G C GW+A G V +PI P P C G Sbjct: 255 RLTLSEAHAACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGL 314 Query: 106 GKTGIIDYGIRLNRSERWDAYCY 128 G+ +G + + YCY Sbjct: 315 PDPGVRSFGFPRPQQAAYGTYCY 337 >gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] Length = 1662 Score = 75.5 bits (184), Expect = 5e-14 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 3/110 (2%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + P F SP +P Y +N C W I ++ R+ + F D LE GC DY+E Sbjct: 1257 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIE 1314 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 ++D + R C D S+ N M+++F+SD S+T GF+ +Y Sbjct: 1315 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1363 Score = 68.2 bits (165), Expect = 8e-12 Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLAD 191 + CGG F SP +P Y +N C W I + G RI+L F + LE C D Sbjct: 1012 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1071 Query: 192 YVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 YVEI+D + +G+ C D S+ N MT+ F SD S GF Y Sbjct: 1072 YVEIFDGSLNSSLLLGKICND-TRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1123 >gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] Length = 1788 Score = 75.5 bits (184), Expect = 5e-14 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 3/110 (2%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + P F SP +P Y +N C W I ++ R+ + F D LE GC DY+E Sbjct: 1383 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIE 1440 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 ++D + R C D S+ N M+++F+SD S+T GF+ +Y Sbjct: 1441 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1489 Score = 68.2 bits (165), Expect = 8e-12 Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLAD 191 + CGG F SP +P Y +N C W I + G RI+L F + LE C D Sbjct: 1138 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1197 Query: 192 YVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 YVEI+D + +G+ C D S+ N MT+ F SD S GF Y Sbjct: 1198 YVEIFDGSLNSSLLLGKICND-TRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1249 >gi|148539844 deleted in malignant brain tumors 1 isoform c precursor [Homo sapiens] Length = 2403 Score = 75.5 bits (184), Expect = 5e-14 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 3/110 (2%) Query: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYVE 194 CGG + P F SP +P Y +N C W I ++ R+ + F D LE GC DY+E Sbjct: 1998 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIE 2055 Query: 195 IYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 ++D + R C D S+ N M+++F+SD S+T GF+ +Y Sbjct: 2056 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2104 Score = 68.2 bits (165), Expect = 8e-12 Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 1/113 (0%) Query: 132 AKECGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLAD 191 + CGG F SP +P Y +N C W I + G RI+L F + LE C D Sbjct: 1753 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1812 Query: 192 YVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKY 244 YVEI+D + +G+ C D S+ N MT+ F SD S GF Y Sbjct: 1813 YVEIFDGSLNSSLLLGKICND-TRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1864 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.141 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,559,369 Number of Sequences: 37866 Number of extensions: 526395 Number of successful extensions: 1160 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 719 Number of HSP's gapped (non-prelim): 286 length of query: 277 length of database: 18,247,518 effective HSP length: 101 effective length of query: 176 effective length of database: 14,423,052 effective search space: 2538457152 effective search space used: 2538457152 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.