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Search of human proteins with 26051218
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 926 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 910 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 841 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 830 0.0
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 829 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 829 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 829 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 829 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 825 0.0
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 825 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 824 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 806 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 802 0.0
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 798 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 690 0.0
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 690 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 650 0.0
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 650 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 603 e-172
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 603 e-172
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 598 e-171
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 276 4e-74
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 237 2e-62
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 237 2e-62
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 234 1e-61
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 224 2e-58
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 223 4e-58
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 223 4e-58
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 926 bits (2394), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLV 360
KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLV
Sbjct: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLV 360
Query: 361 EGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQS 420
EGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQS
Sbjct: 361 EGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQS 420
Query: 421 EETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
EETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 421 EETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 910 bits (2353), Expect = 0.0
Identities = 449/479 (93%), Positives = 449/479 (93%), Gaps = 30/479 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA------------------------------RKQEIIKTTEQLIE 330
KGAILTTMLATRNFSA RKQEIIKTTEQLIE
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 360
Query: 331 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 390
AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV
Sbjct: 361 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 420
Query: 391 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 421 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 479
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 841 bits (2173), Expect = 0.0
Identities = 415/495 (83%), Positives = 431/495 (87%), Gaps = 46/495 (9%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA-------------------------------------------- 316
KGAILTTML +RNFSA
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
Query: 317 --RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLL 374
RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL
Sbjct: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
Query: 375 AKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQ 434
+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW
Sbjct: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
Query: 435 NVHFHCSGAPVAPLQ 449
NVH+HCSGAP APLQ
Sbjct: 481 NVHYHCSGAPAAPLQ 495
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 830 bits (2143), Expect = 0.0
Identities = 420/503 (83%), Positives = 426/503 (84%), Gaps = 54/503 (10%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYA------------KICDPGL 348
KGAILTTMLATRNFSA K + K + + N+ A A + D
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 360
Query: 349 TSFEPE------------------------------------------ALGNLVEGMDFH 366
T+ E E ALGNLVEGMDFH
Sbjct: 361 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 420
Query: 367 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 426
RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW
Sbjct: 421 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 480
Query: 427 HRRDGKWQNVHFHCSGAPVAPLQ 449
HRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 481 HRRDGKWQNVHFHCSGAPVAPLQ 503
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 829 bits (2142), Expect = 0.0
Identities = 401/478 (83%), Positives = 429/478 (89%), Gaps = 29/478 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-----------------------------ARKQEIIKTTEQLIEA 331
KGAILTTMLATRNFS ARKQEIIK TEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 332 VNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVH 391
+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 392 VIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 829 bits (2142), Expect = 0.0
Identities = 401/478 (83%), Positives = 429/478 (89%), Gaps = 29/478 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-----------------------------ARKQEIIKTTEQLIEA 331
KGAILTTMLATRNFS ARKQEIIK TEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 332 VNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVH 391
+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 392 VIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 829 bits (2142), Expect = 0.0
Identities = 401/478 (83%), Positives = 429/478 (89%), Gaps = 29/478 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-----------------------------ARKQEIIKTTEQLIEA 331
KGAILTTMLATRNFS ARKQEIIK TEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 332 VNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVH 391
+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 392 VIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P++
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 478
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 829 bits (2141), Expect = 0.0
Identities = 401/477 (84%), Positives = 428/477 (89%), Gaps = 29/477 (6%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-----------------------------ARKQEIIKTTEQLIEA 331
KGAILTTMLATRNFS ARKQEIIK TEQLIEA
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 332 VNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVH 391
+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILNPHVH
Sbjct: 361 INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH 420
Query: 392 VIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPL 448
++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P+
Sbjct: 421 LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPI 477
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 825 bits (2131), Expect = 0.0
Identities = 401/489 (82%), Positives = 429/489 (87%), Gaps = 40/489 (8%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSA----------------------------------------RKQE 320
KGAILTTMLATRNFSA RKQE
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKKRKSSSSVQMMESTESSNTTIEDEDVKARKQE 360
Query: 321 IIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKP 380
IIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KP
Sbjct: 361 IIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKP 420
Query: 381 IHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHC 440
IHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH
Sbjct: 421 IHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHR 480
Query: 441 SGAPVAPLQ 449
SG+P P++
Sbjct: 481 SGSPTVPIK 489
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 825 bits (2131), Expect = 0.0
Identities = 411/504 (81%), Positives = 428/504 (84%), Gaps = 55/504 (10%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIK------------------------------------- 323
KGAILTTML +RNFSA K + K
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360
Query: 324 --TTE----------------QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDF 365
TTE QLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDF
Sbjct: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420
Query: 366 HRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 425
H+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480
Query: 426 WHRRDGKWQNVHFHCSGAPVAPLQ 449
WHRRDGKW NVH+HCSGAP APLQ
Sbjct: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 824 bits (2128), Expect = 0.0
Identities = 401/492 (81%), Positives = 429/492 (87%), Gaps = 43/492 (8%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFS-------------------------------------------AR 317
KGAILTTMLATRNFS AR
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKAR 360
Query: 318 KQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKN 377
KQEIIK TEQLIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K+
Sbjct: 361 KQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKS 420
Query: 378 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH 437
+KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVH
Sbjct: 421 NKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVH 480
Query: 438 FHCSGAPVAPLQ 449
FH SG+P P++
Sbjct: 481 FHRSGSPTVPIK 492
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 806 bits (2083), Expect = 0.0
Identities = 411/492 (83%), Positives = 418/492 (84%), Gaps = 43/492 (8%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIK---------TTEQLIE------------------AVN 333
KGAILTTMLATRNFS +Q TT L+E V
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKEPQTTVI 360
Query: 334 NGDFEAYAKICDPGLTSFE--------------PEALGNLVEGMDF--HRFYFENLLAKN 377
+ + + D T+ E E L V DF + FYFENLLAKN
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAFYFENLLAKN 420
Query: 378 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH 437
SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH
Sbjct: 421 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVH 480
Query: 438 FHCSGAPVAPLQ 449
FHCSGAPVAPLQ
Sbjct: 481 FHCSGAPVAPLQ 492
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 802 bits (2072), Expect = 0.0
Identities = 385/471 (81%), Positives = 421/471 (89%), Gaps = 30/471 (6%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFS------------------------------ARKQEIIKTTEQLIEAVN 333
ILTTMLATRNFS RKQEIIK TEQLIEA++
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAIS 362
Query: 334 NGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVI 393
NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+H++
Sbjct: 363 NGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLM 422
Query: 394 GEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAP 444
G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 423 GDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAP 473
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 798 bits (2061), Expect = 0.0
Identities = 385/482 (79%), Positives = 421/482 (87%), Gaps = 41/482 (8%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFS-----------------------------------------ARKQEII 322
ILTTMLATRNFS RKQEII
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEII 362
Query: 323 KTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIH 382
K TEQLIEA++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+H
Sbjct: 363 KVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVH 422
Query: 383 TTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSG 442
TTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SG
Sbjct: 423 TTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSG 482
Query: 443 AP 444
AP
Sbjct: 483 AP 484
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 690 bits (1781), Expect = 0.0
Identities = 365/518 (70%), Positives = 388/518 (74%), Gaps = 69/518 (13%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYP-----------------------PFWD- 216
LSPEVLRKEAYGKPVDIWACGVILYILLVGYP P WD
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 217 ---EDQHKLYQQI------KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEAL 267
E ++ + Q + + A++ W +++++ T+ K+ A L
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 268 KHPWVCQR------STVASMMHRQET-----VECLKKFNARRKLKGAI------------ 304
K + S S+++++ K A KG +
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 360
Query: 305 -------------LTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 351
T + + ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 420
Query: 352 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 411
EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 421 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480
Query: 412 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 690 bits (1780), Expect = 0.0
Identities = 364/517 (70%), Positives = 389/517 (75%), Gaps = 68/517 (13%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYP-----------------------PFWD- 216
LSPEVLRKEAYGKPVDIWACGVILYILLVGYP P WD
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 217 ---EDQHKLYQQI------KAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEAL 267
E ++ + Q + + A++ W +++++ T+ K+ A L
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 268 KHPWVC-----QRSTVASMMHRQET-----VECLKKFNARRKLKGAI------------- 304
K + + + S+++++ K A KG +
Sbjct: 301 KGAILTTMLATRNFSAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIH 360
Query: 305 ------------LTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 352
T + + ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE
Sbjct: 361 NPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 420
Query: 353 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 412
PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ
Sbjct: 421 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 480
Query: 413 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 481 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 650 bits (1677), Expect = 0.0
Identities = 317/325 (97%), Positives = 318/325 (97%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTT 325
KGAILTTMLATRNFS +Q T
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPAT 325
Score = 281 bits (720), Expect = 6e-76
Identities = 133/134 (99%), Positives = 134/134 (100%)
Query: 316 ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 375
+RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA
Sbjct: 533 SRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 592
Query: 376 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 435
KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN
Sbjct: 593 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 652
Query: 436 VHFHCSGAPVAPLQ 449
VHFHCSGAPVAPLQ
Sbjct: 653 VHFHCSGAPVAPLQ 666
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 650 bits (1677), Expect = 0.0
Identities = 317/325 (97%), Positives = 318/325 (97%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTT 325
KGAILTTMLATRNFS +Q T
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPAT 325
Score = 284 bits (726), Expect = 1e-76
Identities = 135/143 (94%), Positives = 137/143 (95%)
Query: 307 TMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 366
T + + ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH
Sbjct: 400 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 459
Query: 367 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 426
RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW
Sbjct: 460 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 519
Query: 427 HRRDGKWQNVHFHCSGAPVAPLQ 449
HRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 520 HRRDGKWQNVHFHCSGAPVAPLQ 542
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 603 bits (1555), Expect = e-172
Identities = 297/356 (83%), Positives = 319/356 (89%), Gaps = 2/356 (0%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPG--LTSFEPE 354
KGAILTTML +RNFSA K + K ++ ++ +N + +P T+ EP+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQ 356
Score = 271 bits (694), Expect = 7e-73
Identities = 130/157 (82%), Positives = 137/157 (87%), Gaps = 2/157 (1%)
Query: 295 NARRKLKGAI--LTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE 352
NA +KG+ T + RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFE
Sbjct: 362 NATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFE 421
Query: 353 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 412
PEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ
Sbjct: 422 PEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ 481
Query: 413 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
GRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 482 GRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 603 bits (1555), Expect = e-172
Identities = 297/356 (83%), Positives = 319/356 (89%), Gaps = 2/356 (0%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPG--LTSFEPE 354
KGAILTTML +RNFSA K + K ++ ++ +N + +P T+ EP+
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQ 356
Score = 269 bits (688), Expect = 3e-72
Identities = 125/133 (93%), Positives = 129/133 (96%)
Query: 317 RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAK 376
RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+K
Sbjct: 424 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 483
Query: 377 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNV 436
NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NV
Sbjct: 484 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 543
Query: 437 HFHCSGAPVAPLQ 449
H+HCSGAP APLQ
Sbjct: 544 HYHCSGAPAAPLQ 556
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 598 bits (1543), Expect = e-171
Identities = 290/319 (90%), Positives = 303/319 (94%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSARKQ 319
KGAILTTML +RNFS +Q
Sbjct: 301 KGAILTTMLVSRNFSVGRQ 319
Score = 272 bits (696), Expect = 4e-73
Identities = 135/176 (76%), Positives = 144/176 (81%), Gaps = 6/176 (3%)
Query: 276 STVASMMHRQETVECLKKFNARRKLKGAI--LTTMLATRNFSARKQEIIKTTEQLIEAVN 333
S+ +M Q TV NA +KG+ T + RKQEIIK TEQLIEA+N
Sbjct: 356 SSSVHLMEPQTTVV----HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAIN 411
Query: 334 NGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVI 393
NGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVI
Sbjct: 412 NGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVI 471
Query: 394 GEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 449
GEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 472 GEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 276 bits (705), Expect = 4e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 237 bits (604), Expect = 2e-62
Identities = 122/294 (41%), Positives = 179/294 (60%), Gaps = 3/294 (1%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTT 307
+P KR T +A +HPW+ + + +H + + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 237 bits (604), Expect = 2e-62
Identities = 122/294 (41%), Positives = 179/294 (60%), Gaps = 3/294 (1%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTT 307
+P KR T +A +HPW+ + + +H + + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 234 bits (597), Expect = 1e-61
Identities = 129/308 (41%), Positives = 194/308 (62%), Gaps = 10/308 (3%)
Query: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
+D +++ ++G+GA S+V RC + T YA K++ D + + E + L H
Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98
Query: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
NI++L + LV +LVTGGELF+ IV + YYSE DA+ ++QILEAV + H+
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 131 GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
G+VHRDLKPENLL A+ A +K+ADFGL+ ++ Q GTPGY +PE+LR A
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AK+L
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
+ +++ ++P KR+T +AL+HPWV ++ A+ +H + L++FNARRKLK A+ +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334
Query: 309 LATRNFSA 316
++R SA
Sbjct: 335 ASSRLGSA 342
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 224 bits (570), Expect = 2e-58
Identities = 122/296 (41%), Positives = 174/296 (58%), Gaps = 3/296 (1%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
D Y + +G GAFS V T A K I + L ++ +E E + +KH
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NIV L D G YL+ LV+GGELF+ IV + +Y+E DAS I Q+L+AV + H +G
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY 191
+VHRDLKPENLL S + + + ++DFGL+ +++ GTPGY++PEVL ++ Y
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
K VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 252 MLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTT 307
++ +P KR T +AL+HPW+ + + +H Q E +KK A+ K K A T
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNAT 310
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 223 bits (567), Expect = 4e-58
Identities = 121/311 (38%), Positives = 181/311 (58%), Gaps = 7/311 (2%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 391 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 449
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 450 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 509
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 510 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 566
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 567 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 626
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 627 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 686
Query: 309 LATRNFSARKQ 319
N + K+
Sbjct: 687 SVIMNTALDKE 697
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 223 bits (567), Expect = 4e-58
Identities = 121/311 (38%), Positives = 181/311 (58%), Gaps = 7/311 (2%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 392 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 450
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 510
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 511 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 567
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 568 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 627
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 628 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 687
Query: 309 LATRNFSARKQ 319
N + K+
Sbjct: 688 SVIMNTALDKE 698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,567,208
Number of Sequences: 37866
Number of extensions: 784484
Number of successful extensions: 4107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 570
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 1854
Number of HSP's gapped (non-prelim): 982
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.