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Search of human proteins with 26051206
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
(542 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 1105 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 1045 0.0
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 1044 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 1003 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 976 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 947 0.0
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 929 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 919 0.0
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 912 0.0
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 902 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 899 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 880 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 857 0.0
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 852 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 852 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 852 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 851 0.0
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 832 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 829 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 827 0.0
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 650 0.0
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 276 5e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 276 5e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 276 5e-74
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 237 2e-62
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 237 2e-62
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 233 3e-61
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 225 7e-59
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 223 5e-58
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 223 5e-58
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 1105 bits (2857), Expect = 0.0
Identities = 542/542 (100%), Positives = 542/542 (100%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
Query: 541 LQ 542
LQ
Sbjct: 541 LQ 542
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 1045 bits (2701), Expect = 0.0
Identities = 517/542 (95%), Positives = 517/542 (95%), Gaps = 24/542 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLLNKKADGVKPQTNSTK 336
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 337 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 396
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 397 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 456
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 457 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 516
Query: 541 LQ 542
LQ
Sbjct: 517 LQ 518
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 1044 bits (2700), Expect = 0.0
Identities = 517/542 (95%), Positives = 517/542 (95%), Gaps = 25/542 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFS-------------------------AKSLLNKKADGVKPQTNSTK 335
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 336 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 395
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 396 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 455
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 456 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 515
Query: 541 LQ 542
LQ
Sbjct: 516 LQ 517
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 1003 bits (2594), Expect = 0.0
Identities = 502/542 (92%), Positives = 502/542 (92%), Gaps = 39/542 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLLNKKADGVKPQTNSTK 336
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
NSAAATSPKGTLPPAAL ESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 337 NSAAATSPKGTLPPAAL---------------ESSDSANTTIEDEDAKARKQEIIKTTEQ 381
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 382 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 441
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 442 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 501
Query: 541 LQ 542
LQ
Sbjct: 502 LQ 503
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 976 bits (2522), Expect = 0.0
Identities = 492/542 (90%), Positives = 492/542 (90%), Gaps = 50/542 (9%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVK------- 353
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
EPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 354 -----------------EPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 396
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYA FYFENLLAKNSKPIHTTILN
Sbjct: 397 LIEAVNNGDFEAYA--------------------------FYFENLLAKNSKPIHTTILN 430
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 431 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 490
Query: 541 LQ 542
LQ
Sbjct: 491 LQ 492
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 947 bits (2449), Expect = 0.0
Identities = 478/542 (88%), Positives = 478/542 (88%), Gaps = 63/542 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLLNKKADGV
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLLNKKADGV-------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
KESSDSANTTIEDEDAKARKQEIIKTTEQ
Sbjct: 329 -------------------------------KESSDSANTTIEDEDAKARKQEIIKTTEQ 357
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN
Sbjct: 358 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 417
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP
Sbjct: 418 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 477
Query: 541 LQ 542
LQ
Sbjct: 478 LQ 479
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 929 bits (2401), Expect = 0.0
Identities = 458/543 (84%), Positives = 489/543 (90%), Gaps = 17/543 (3%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359
KGAILTTML +RNFSVGRQ++APA+ + +A+G + AKSLLNKK+D GVK + +S+
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLA---GQAAKSLLNKKSDGGVKKRKSSS 357
Query: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTE 419
+EPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TE
Sbjct: 358 S-------------VHLMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITE 404
Query: 420 QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTIL 479
QLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTIL
Sbjct: 405 QLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTIL 464
Query: 480 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVA 539
NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP A
Sbjct: 465 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAA 524
Query: 540 PLQ 542
PLQ
Sbjct: 525 PLQ 527
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 919 bits (2376), Expect = 0.0
Identities = 455/543 (83%), Positives = 481/543 (88%), Gaps = 26/543 (4%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+
Sbjct: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335
Query: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTE 419
KNS + + + A+EPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TE
Sbjct: 336 KNSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITE 395
Query: 420 QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTIL 479
QLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTIL
Sbjct: 396 QLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTIL 455
Query: 480 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVA 539
NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP A
Sbjct: 456 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAA 515
Query: 540 PLQ 542
PLQ
Sbjct: 516 PLQ 518
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 912 bits (2358), Expect = 0.0
Identities = 455/543 (83%), Positives = 477/543 (87%), Gaps = 40/543 (7%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKPQTNST 359
KGAILTTML +RNFS AKSLLNKK+D GVKPQ+N+
Sbjct: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335
Query: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTE 419
KNS LEPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TE
Sbjct: 336 KNS--------------LEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITE 381
Query: 420 QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTIL 479
QLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTIL
Sbjct: 382 QLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTIL 441
Query: 480 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVA 539
NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP A
Sbjct: 442 NPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAA 501
Query: 540 PLQ 542
PLQ
Sbjct: 502 PLQ 504
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 902 bits (2331), Expect = 0.0
Identities = 456/581 (78%), Positives = 482/581 (82%), Gaps = 64/581 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADG-VKPQTNST 359
KGAILTTML +RNFS AKSLLNKK+DG VKPQ+N+
Sbjct: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKPQSNN- 335
Query: 360 KNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA---------- 409
KNS + + + A+EPQTTV+HN DGIK S++S NTT EDED KA
Sbjct: 336 KNSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSS 395
Query: 410 ----------------------------RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGL 441
RKQEIIK TEQLIEA+NNGDFEAY KICDPGL
Sbjct: 396 VPEGRSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGL 455
Query: 442 TSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY 501
TSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY
Sbjct: 456 TSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQY 515
Query: 502 IDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 542
IDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 516 IDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 556
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 899 bits (2323), Expect = 0.0
Identities = 446/542 (82%), Positives = 466/542 (85%), Gaps = 47/542 (8%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK + EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V H HQ +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTML +RNFS AKSLLNKK+DG
Sbjct: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDG--------- 327
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
EPQTTV+HN DGIK S++S NTT EDED K RKQEIIK TEQ
Sbjct: 328 --------------GVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQ 373
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILN
Sbjct: 374 LIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILN 433
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP AP
Sbjct: 434 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAP 493
Query: 541 LQ 542
LQ
Sbjct: 494 LQ 495
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 880 bits (2273), Expect = 0.0
Identities = 437/542 (80%), Positives = 468/542 (86%), Gaps = 50/542 (9%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
EPQTTVIHNP DG KES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 329 -----------------EPQTTVIHNP-DGNKESTESSNTTIEDEDVKARKQEIIKVTEQ 370
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 371 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 430
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 431 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 490
Query: 541 LQ 542
++
Sbjct: 491 IK 492
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 857 bits (2213), Expect = 0.0
Identities = 425/542 (78%), Positives = 460/542 (84%), Gaps = 53/542 (9%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK + +S+
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVKKRKSSSS 335
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
+ ES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 336 VQ----------------------------MMESTESSNTTIEDEDVKARKQEIIKVTEQ 367
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 368 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 427
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 428 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 487
Query: 541 LQ 542
++
Sbjct: 488 IK 489
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 852 bits (2200), Expect = 0.0
Identities = 424/542 (78%), Positives = 455/542 (83%), Gaps = 64/542 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
ES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 329 --------------------------------ESTESSNTTIEDEDVKARKQEIIKVTEQ 356
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 357 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 416
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 417 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 476
Query: 541 LQ 542
++
Sbjct: 477 IK 478
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 852 bits (2200), Expect = 0.0
Identities = 424/542 (78%), Positives = 455/542 (83%), Gaps = 64/542 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
ES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 329 --------------------------------ESTESSNTTIEDEDVKARKQEIIKVTEQ 356
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 357 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 416
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 417 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 476
Query: 541 LQ 542
++
Sbjct: 477 IK 478
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 852 bits (2200), Expect = 0.0
Identities = 424/542 (78%), Positives = 455/542 (83%), Gaps = 64/542 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
ES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 329 --------------------------------ESTESSNTTIEDEDVKARKQEIIKVTEQ 356
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 357 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 416
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 417 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 476
Query: 541 LQ 542
++
Sbjct: 477 IK 478
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 851 bits (2199), Expect = 0.0
Identities = 424/541 (78%), Positives = 454/541 (83%), Gaps = 64/541 (11%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MA+T TCTRFTDEYQL+E++GKGAFSVVRRC+K+ TG EYAAKIINTKKLSARDHQKLER
Sbjct: 1 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LE+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAK+LIN+MLTINPAKRITA EALKHPW+CQRSTVASMMHRQETV+CLKKFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFS AKSLL KK DGVK
Sbjct: 301 KGAILTTMLATRNFSA------------------------AKSLL-KKPDGVK------- 328
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420
ES++S+NTTIEDED KARKQEIIK TEQ
Sbjct: 329 --------------------------------ESTESSNTTIEDEDVKARKQEIIKVTEQ 356
Query: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480
LIEA+NNGDFEAY KICDPGLT+FEPEALGNLVEGMDFHRFYFEN L+K++KPIHT ILN
Sbjct: 357 LIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILN 416
Query: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540
PHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKWQNVHFH SG+P P
Sbjct: 417 PHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVP 476
Query: 541 L 541
+
Sbjct: 477 I 477
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 832 bits (2150), Expect = 0.0
Identities = 409/534 (76%), Positives = 451/534 (84%), Gaps = 52/534 (9%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSA 363
ILTTMLATRNFS G KS NKK+DGVK + +S+
Sbjct: 303 ILTTMLATRNFSGG------------------------KSGGNKKSDGVKKRKSSSSVQ- 337
Query: 364 AATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 423
+ ESS+S NTTIEDED K RKQEIIK TEQLIE
Sbjct: 338 ---------------------------LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIE 370
Query: 424 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 483
A++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+
Sbjct: 371 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI 430
Query: 484 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAP 537
H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 431 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 829 bits (2141), Expect = 0.0
Identities = 417/447 (93%), Positives = 423/447 (94%), Gaps = 6/447 (1%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360
Query: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA-RKQEIIKTTE 419
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKA R +I+ +
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVR 420
Query: 420 QLIEAVNNGDFEAYAKICDPGLTSFEP 446
+ +G EA + P F P
Sbjct: 421 R-----GSGAPEAEGPLPCPSPAPFSP 442
Score = 281 bits (720), Expect = 8e-76
Identities = 133/134 (99%), Positives = 134/134 (100%)
Query: 409 ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 468
+RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA
Sbjct: 533 SRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLA 592
Query: 469 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 528
KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN
Sbjct: 593 KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQN 652
Query: 529 VHFHCSGAPVAPLQ 542
VHFHCSGAPVAPLQ
Sbjct: 653 VHFHCSGAPVAPLQ 666
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 827 bits (2136), Expect = 0.0
Identities = 408/534 (76%), Positives = 446/534 (83%), Gaps = 63/534 (11%)
Query: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
Query: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
Query: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
Query: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
Query: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
Query: 304 ILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSA 363
ILTTMLATRNFS G KS NKK+DGVK
Sbjct: 303 ILTTMLATRNFSGG------------------------KSGGNKKSDGVK---------- 328
Query: 364 AATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 423
ESS+S NTTIEDED K RKQEIIK TEQLIE
Sbjct: 329 -----------------------------ESSESTNTTIEDEDTKVRKQEIIKVTEQLIE 359
Query: 424 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 483
A++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+
Sbjct: 360 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI 419
Query: 484 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAP 537
H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 420 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAP 473
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 650 bits (1677), Expect = 0.0
Identities = 317/325 (97%), Positives = 318/325 (97%)
Query: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
Sbjct: 1 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60
Query: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
Sbjct: 61 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120
Query: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180
Query: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
Query: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300
Query: 301 KGAILTTMLATRNFSVGRQTTAPAT 325
KGAILTTMLATRNFS +Q T
Sbjct: 301 KGAILTTMLATRNFSARKQEIIKTT 325
Score = 284 bits (726), Expect = 2e-76
Identities = 135/143 (94%), Positives = 137/143 (95%)
Query: 400 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 459
T + + ARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH
Sbjct: 307 TMLATRNFSARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 366
Query: 460 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 519
RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW
Sbjct: 367 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 426
Query: 520 HRRDGKWQNVHFHCSGAPVAPLQ 542
HRRDGKWQNVHFHCSGAPVAPLQ
Sbjct: 427 HRRDGKWQNVHFHCSGAPVAPLQ 449
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 276 bits (705), Expect = 5e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 276 bits (705), Expect = 5e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 276 bits (705), Expect = 5e-74
Identities = 143/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 10 FTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSAR---DHQKLEREARICR 66
F D Y+L E IGKG FSVVRRC+ TG ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 67 LLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 122
+LKH +IV L ++ S +G Y+VF+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 183 PEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
PEV+++E YGKPVD+W CGVIL+ILL G PF+ + +L++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 243 PEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKG 302
AK+L+ +ML ++PA+RIT +EAL HPW+ +R A +H ETVE L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 303 AILTTM 308
A+L +
Sbjct: 307 AVLAAV 312
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 237 bits (605), Expect = 2e-62
Identities = 129/333 (38%), Positives = 193/333 (57%), Gaps = 9/333 (2%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLA--T 311
+P KR T +A +HPW+ + + +H + + K F A+ K + A T +
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNATAVVRHM 319
Query: 312 RNFSVGRQTTAPATMSTAASGTTMGLVEQAKSL 344
R +G + S A+ +++ L Q L
Sbjct: 320 RKLHLGSSLDS----SNASVSSSLSLASQKDCL 348
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 237 bits (604), Expect = 2e-62
Identities = 122/294 (41%), Positives = 179/294 (60%), Gaps = 3/294 (1%)
Query: 14 YQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNI 73
++ E +G GAFS V + TG +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 74 VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 133
V L D YLV LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGK 193
HRDLKPENLL S+ + + + ++DFGL+ +++G GTPGY++PEVL ++ Y K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 254 TINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTT 307
+P KR T +A +HPW+ + + +H + + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 233 bits (595), Expect = 3e-61
Identities = 127/304 (41%), Positives = 192/304 (63%), Gaps = 10/304 (3%)
Query: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
+D +++ ++G+GA S+V RC + T YA K++ D + + E + L H
Sbjct: 43 SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98
Query: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
NI++L + LV +LVTGGELF+ IV + YYSE DA+ ++QILEAV + H+
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 131 GVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
G+VHRDLKPENLL A+ A +K+ADFGL+ ++ Q GTPGY +PE+LR A
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AK+L
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
+ +++ ++P KR+T +AL+HPWV ++ A+ +H + L++FNARRKLK A+ +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334
Query: 309 LATR 312
++R
Sbjct: 335 ASSR 338
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 225 bits (574), Expect = 7e-59
Identities = 126/321 (39%), Positives = 182/321 (56%), Gaps = 3/321 (0%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
D Y + +G GAFS V T A K I + L ++ +E E + +KH
Sbjct: 18 DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NIV L D G YL+ LV+GGELF+ IV + +Y+E DAS I Q+L+AV + H +G
Sbjct: 77 NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 132 VVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAY 191
+VHRDLKPENLL S + + + ++DFGL+ +++ GTPGY++PEVL ++ Y
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
K VD W+ GVI YILL GYPPF+DE+ KL++QI Y+F SP WD ++ AK+ I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 252 MLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLAT 311
++ +P KR T +AL+HPW+ + + +H Q E +KK A+ K K A T +
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNATAVVR 314
Query: 312 RNFSVGRQTTAPATMSTAASG 332
+ T+ TA+ G
Sbjct: 315 HMRKLQLGTSQEGQGQTASHG 335
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 223 bits (567), Expect = 5e-58
Identities = 120/311 (38%), Positives = 182/311 (58%), Gaps = 7/311 (2%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 391 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 449
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 450 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 509
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 510 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 566
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 567 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 626
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 627 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 686
Query: 309 LATRNFSVGRQ 319
N ++ ++
Sbjct: 687 SVIMNTALDKE 697
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 223 bits (567), Expect = 5e-58
Identities = 120/311 (38%), Positives = 182/311 (58%), Gaps = 7/311 (2%)
Query: 12 DEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHS 71
++Y++ + IG G F+VV+ C+ TG E+A KII+ K ++H +E E I R +KH
Sbjct: 392 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHL-IENEVSILRRVKHP 450
Query: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMG 131
NI+ L + + +LV +LV GG+LF+ I + Y+E D S + + A+ + H +
Sbjct: 451 NIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLS 510
Query: 132 VVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEA 190
+VHRD+KPENLL+ G ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 511 IVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEG---PLYTVCGTPTYVAPEIIAETG 567
Query: 191 YGKPVDIWACGVILYILLVGYPPFWDED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
YG VDIWA GVI YILL G+PPF E+ Q L+ QI AG +FP+P WD +T AK L
Sbjct: 568 YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKEL 627
Query: 249 INQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTM 308
I+QML +N R TA + L HPWV ++ + M + T + + FN + + T +
Sbjct: 628 ISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGV 687
Query: 309 LATRNFSVGRQ 319
N ++ ++
Sbjct: 688 SVIMNTALDKE 698
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,894,611
Number of Sequences: 37866
Number of extensions: 937478
Number of successful extensions: 5394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 569
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 2971
Number of HSP's gapped (non-prelim): 1177
length of query: 542
length of database: 18,247,518
effective HSP length: 107
effective length of query: 435
effective length of database: 14,195,856
effective search space: 6175197360
effective search space used: 6175197360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.