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Search of human proteins with 25952114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25952114 calcium/calmodulin-dependent protein kinase II
alpha isoform 1 [Homo sapiens]
(489 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 999 0.0
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 972 0.0
gi|212549756 calcium/calmodulin-dependent protein kinase II delt... 884 0.0
gi|212549753 calcium/calmodulin-dependent protein kinase II delt... 857 0.0
gi|26667183 calcium/calmodulin-dependent protein kinase II delta... 857 0.0
gi|26667186 calcium/calmodulin-dependent protein kinase II delta... 857 0.0
gi|26667189 calcium/calmodulin-dependent protein kinase II delta... 857 0.0
gi|26667180 calcium/calmodulin-dependent protein kinase II delta... 857 0.0
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 850 0.0
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 850 0.0
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 845 0.0
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 840 0.0
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 837 0.0
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 834 0.0
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 832 0.0
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 831 0.0
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 827 0.0
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 807 0.0
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 798 0.0
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 774 0.0
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 606 e-173
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 277 2e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 277 2e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 277 2e-74
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 243 2e-64
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 243 2e-64
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 242 6e-64
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 232 5e-61
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 231 1e-60
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 230 3e-60
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 999 bits (2583), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 60
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
Sbjct: 1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 60
Query: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
Sbjct: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 180
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 180
Query: 181 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
Sbjct: 181 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 300
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 300
Query: 301 GAILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE 360
GAILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
Sbjct: 301 GAILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE 360
Query: 361 IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP 420
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
Sbjct: 361 IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP 420
Query: 421 VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR 480
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
Sbjct: 421 VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR 480
Query: 481 SGAPSVLPH 489
SGAPSVLPH
Sbjct: 481 SGAPSVLPH 489
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 972 bits (2512), Expect = 0.0
Identities = 478/489 (97%), Positives = 478/489 (97%), Gaps = 11/489 (2%)
Query: 1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 60
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
Sbjct: 1 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 60
Query: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
Sbjct: 61 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 120
Query: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 180
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 180
Query: 181 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
Sbjct: 181 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 300
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 300
Query: 301 GAILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE 360
GAILTTMLATRNFSGGKSGGNKKSDGVK ESSESTNTTIEDEDTKVRKQE
Sbjct: 301 GAILTTMLATRNFSGGKSGGNKKSDGVK-----------ESSESTNTTIEDEDTKVRKQE 349
Query: 361 IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP 420
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
Sbjct: 350 IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP 409
Query: 421 VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR 480
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
Sbjct: 410 VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR 469
Query: 481 SGAPSVLPH 489
SGAPSVLPH
Sbjct: 470 SGAPSVLPH 478
>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
isoform 4 [Homo sapiens]
Length = 489
Score = 884 bits (2283), Expect = 0.0
Identities = 425/485 (87%), Positives = 459/485 (94%), Gaps = 1/485 (0%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
AILTTMLATRNFS KS KK DGVKKRKSSSSVQ+MES+ES+NTTIEDED K RKQEI
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVKKRKSSSSVQMMESTESSNTTIEDEDVKARKQEI 361
Query: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 362 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 421
Query: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 422 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 481
Query: 482 GAPSV 486
G+P+V
Sbjct: 482 GSPTV 486
>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
isoform 5 [Homo sapiens]
Length = 492
Score = 857 bits (2215), Expect = 0.0
Identities = 415/488 (85%), Positives = 453/488 (92%), Gaps = 4/488 (0%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSS---SSVQLMESSESTNTTIEDEDTKVRK 358
AILTTMLATRNFS KS KK DGVK+ +++ + ES+ES+NTTIEDED K RK
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVKEPQTTVIHNPDGNKESTESSNTTIEDEDVKARK 361
Query: 359 QEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNS 418
QEIIKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++
Sbjct: 362 QEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSN 421
Query: 419 KPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHF 478
KP+HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHF
Sbjct: 422 KPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHF 481
Query: 479 HRSGAPSV 486
HRSG+P+V
Sbjct: 482 HRSGSPTV 489
>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 857 bits (2214), Expect = 0.0
Identities = 415/485 (85%), Positives = 448/485 (92%), Gaps = 12/485 (2%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
AILTTMLATRNFS KS KK DGVK ES+ES+NTTIEDED K RKQEI
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVK-----------ESTESSNTTIEDEDVKARKQEI 350
Query: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 351 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 410
Query: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 411 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 470
Query: 482 GAPSV 486
G+P+V
Sbjct: 471 GSPTV 475
>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
isoform 1 [Homo sapiens]
Length = 478
Score = 857 bits (2214), Expect = 0.0
Identities = 415/485 (85%), Positives = 448/485 (92%), Gaps = 12/485 (2%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
AILTTMLATRNFS KS KK DGVK ES+ES+NTTIEDED K RKQEI
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVK-----------ESTESSNTTIEDEDVKARKQEI 350
Query: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 351 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 410
Query: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 411 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 470
Query: 482 GAPSV 486
G+P+V
Sbjct: 471 GSPTV 475
>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
isoform 2 [Homo sapiens]
Length = 478
Score = 857 bits (2214), Expect = 0.0
Identities = 415/485 (85%), Positives = 448/485 (92%), Gaps = 12/485 (2%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
AILTTMLATRNFS KS KK DGVK ES+ES+NTTIEDED K RKQEI
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVK-----------ESTESSNTTIEDEDVKARKQEI 350
Query: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 351 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 410
Query: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 411 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 470
Query: 482 GAPSV 486
G+P+V
Sbjct: 471 GSPTV 475
>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
isoform 3 [Homo sapiens]
Length = 499
Score = 857 bits (2214), Expect = 0.0
Identities = 415/485 (85%), Positives = 448/485 (92%), Gaps = 12/485 (2%)
Query: 2 ATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREA 61
+T TCTRFT+EYQLFEELGKGAFSVVRRC+K+ GQEYAAKIINTKKLSARDHQKLEREA
Sbjct: 3 STTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREA 62
Query: 62 RICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILE 121
RICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILE
Sbjct: 63 RICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILE 122
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
+V HCH G+VHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLS
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT
Sbjct: 183 PEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 242
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
PEAKDLINKMLTINP+KRITA+EALKHPWI RSTVAS MHRQETVDCLKKFNARRKLKG
Sbjct: 243 PEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKG 302
Query: 302 AILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEI 361
AILTTMLATRNFS KS KK DGVK ES+ES+NTTIEDED K RKQEI
Sbjct: 303 AILTTMLATRNFSAAKS-LLKKPDGVK-----------ESTESSNTTIEDEDVKARKQEI 350
Query: 362 IKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPV 421
IKVTEQLIEAI+NGDFE+YTK+CDPG+TAFEPEALGNLVEG+DFHRFYFEN S+++KP+
Sbjct: 351 IKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI 410
Query: 422 HTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRS 481
HT ILNPH+HL+GD++ACIAYIR+TQY+D G+P+T QSEETRVWHRRDGKWQ VHFHRS
Sbjct: 411 HTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRS 470
Query: 482 GAPSV 486
G+P+V
Sbjct: 471 GSPTV 475
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 850 bits (2197), Expect = 0.0
Identities = 408/495 (82%), Positives = 450/495 (90%), Gaps = 13/495 (2%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSS-------------VQLMESSESTNTTI 349
ILTTMLATRNFS KS NKK+DGVK + +S+ +ESS+S NTTI
Sbjct: 304 ILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSANTTI 363
Query: 350 EDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFY 409
EDED K RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFY
Sbjct: 364 EDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFY 423
Query: 410 FENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRR 469
FENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRR
Sbjct: 424 FENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRR 483
Query: 470 DGKWQIVHFHRSGAP 484
DGKWQ VHFH SGAP
Sbjct: 484 DGKWQNVHFHCSGAP 498
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 850 bits (2196), Expect = 0.0
Identities = 407/482 (84%), Positives = 445/482 (92%), Gaps = 11/482 (2%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEII 362
ILTTMLATRNFS KS NKK+DGVK ESS+S NTTIEDED K RKQEII
Sbjct: 304 ILTTMLATRNFSAAKSLLNKKADGVK-----------ESSDSANTTIEDEDAKARKQEII 352
Query: 363 KVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVH 422
K TEQLIEA++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+H
Sbjct: 353 KTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIH 412
Query: 423 TTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSG 482
TTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SG
Sbjct: 413 TTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSG 472
Query: 483 AP 484
AP
Sbjct: 473 AP 474
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 845 bits (2182), Expect = 0.0
Identities = 408/510 (80%), Positives = 450/510 (88%), Gaps = 28/510 (5%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQ------------------------- 337
ILTTMLATRNFS KS NKK+DGVK + +S+
Sbjct: 304 ILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNP 363
Query: 338 ---LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 394
+ ESS+S NTTIEDED K RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPE
Sbjct: 364 VDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPE 423
Query: 395 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 454
ALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 424 ALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 483
Query: 455 PRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 484 PRTSQSEETRVWHRRDGKWQNVHFHCSGAP 513
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 840 bits (2170), Expect = 0.0
Identities = 408/510 (80%), Positives = 450/510 (88%), Gaps = 29/510 (5%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQ------------------------- 337
ILTTMLATRNFS KS NKK+DGVK + +S+
Sbjct: 304 ILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNP 362
Query: 338 ---LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 394
+ ESS+S NTTIEDED K RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPE
Sbjct: 363 VDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPE 422
Query: 395 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 454
ALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 423 ALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 482
Query: 455 PRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 483 PRTSQSEETRVWHRRDGKWQNVHFHCSGAP 512
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 837 bits (2161), Expect = 0.0
Identities = 412/520 (79%), Positives = 452/520 (86%), Gaps = 37/520 (7%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGG---------------------NKKSD-GVKKRKSSSSVQLME 340
ILTTML +RNFS G+ NKKSD GVKKRKSSSSV LME
Sbjct: 304 ILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLME 363
Query: 341 ---------------SSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCD 385
S+ES NTT EDED KVRKQEIIK+TEQLIEAI+NGDFE+YTK+CD
Sbjct: 364 PQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICD 423
Query: 386 PGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRI 445
PG+T+FEPEALGNLVEG+DFH+FYFENL S+NSKP+HTTILNPH+H++G+++ACIAYIR+
Sbjct: 424 PGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRL 483
Query: 446 TQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPS 485
TQY+D G PRT+QSEETRVWHRRDGKW VH+H SGAP+
Sbjct: 484 TQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPA 523
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 834 bits (2155), Expect = 0.0
Identities = 402/488 (82%), Positives = 444/488 (90%), Gaps = 5/488 (1%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQ-----LMESSESTNTTIEDEDTKVR 357
ILTTML +RNFS KS NKKSDG K ++ V + S+ES NTT EDED KVR
Sbjct: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVR 363
Query: 358 KQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRN 417
KQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+N
Sbjct: 364 KQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKN 423
Query: 418 SKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVH 477
SKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKW VH
Sbjct: 424 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVH 483
Query: 478 FHRSGAPS 485
+H SGAP+
Sbjct: 484 YHCSGAPA 491
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 832 bits (2150), Expect = 0.0
Identities = 409/534 (76%), Positives = 451/534 (84%), Gaps = 52/534 (9%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGG------------------------KSGGNKKSDGVKKRKSSSSVQ- 337
ILTTMLATRNFS G KS NKK+DGVK + +S+
Sbjct: 304 ILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSA 363
Query: 338 ---------------------------LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIE 370
+ ESS+S NTTIEDED K RKQEIIK TEQLIE
Sbjct: 364 AATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 423
Query: 371 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI 430
A++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+HTTILNPH+
Sbjct: 424 AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHV 483
Query: 431 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 484 HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAP 537
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 831 bits (2147), Expect = 0.0
Identities = 403/497 (81%), Positives = 445/497 (89%), Gaps = 14/497 (2%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQL--------------MESSESTNTT 348
ILTTML +RNFS KS NKKSDG K +S++ L S+ES NTT
Sbjct: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESCNTT 363
Query: 349 IEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRF 408
EDED KVRKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+F
Sbjct: 364 TEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKF 423
Query: 409 YFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHR 468
YFENL S+NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHR
Sbjct: 424 YFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHR 483
Query: 469 RDGKWQIVHFHRSGAPS 485
RDGKW VH+H SGAP+
Sbjct: 484 RDGKWLNVHYHCSGAPA 500
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 827 bits (2137), Expect = 0.0
Identities = 403/511 (78%), Positives = 446/511 (87%), Gaps = 28/511 (5%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLME---------------------- 340
ILTTML +RNFS KS NKKSDG K +S++ L+
Sbjct: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVVHNA 363
Query: 341 ------SSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 394
S+ES NTT EDED KVRKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPE
Sbjct: 364 TDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPE 423
Query: 395 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 454
ALGNLVEG+DFH+FYFENL S+NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 424 ALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 483
Query: 455 PRTAQSEETRVWHRRDGKWQIVHFHRSGAPS 485
PRT+QSEETRVWHRRDGKW VH+H SGAP+
Sbjct: 484 PRTSQSEETRVWHRRDGKWLNVHYHCSGAPA 514
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 807 bits (2085), Expect = 0.0
Identities = 402/549 (73%), Positives = 446/549 (81%), Gaps = 66/549 (12%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T TCTRFT++YQLFEELGKGAFSVVRRCVK + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
V H HQ +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA +ALKHPW+ RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLME---------------------- 340
ILTTML +RNFS KS NKKSDG K +S++ L+
Sbjct: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVVHNA 363
Query: 341 ------SSESTNTTIEDEDTK--------------------------------------V 356
S+ES NTT EDED K +
Sbjct: 364 TDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCSSAM 423
Query: 357 RKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSR 416
RKQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+
Sbjct: 424 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 483
Query: 417 NSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIV 476
NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKW V
Sbjct: 484 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 543
Query: 477 HFHRSGAPS 485
H+H SGAP+
Sbjct: 544 HYHCSGAPA 552
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 798 bits (2061), Expect = 0.0
Identities = 385/482 (79%), Positives = 421/482 (87%), Gaps = 41/482 (8%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEII 362
ILTTMLATRNFS RKQEII
Sbjct: 304 ILTTMLATRNFS-----------------------------------------ARKQEII 322
Query: 363 KVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVH 422
K TEQLIEA++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL ++NSKP+H
Sbjct: 323 KTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIH 382
Query: 423 TTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSG 482
TTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKWQ VHFH SG
Sbjct: 383 TTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSG 442
Query: 483 AP 484
AP
Sbjct: 443 AP 444
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 774 bits (1999), Expect = 0.0
Identities = 386/510 (75%), Positives = 425/510 (83%), Gaps = 54/510 (10%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGG------------------------KSGGNKKSDGVKKRKSSSSVQ- 337
ILTTMLATRNFS G KS NKK+DGVK+ +++
Sbjct: 304 ILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKEPQTTVIHNP 363
Query: 338 ---LMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPE 394
+ ESS+S NTTIEDED K RKQEIIK TEQLIEA++NGDFE+Y
Sbjct: 364 VDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA------------- 410
Query: 395 ALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGI 454
FYFENL ++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G
Sbjct: 411 -------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGR 457
Query: 455 PRTAQSEETRVWHRRDGKWQIVHFHRSGAP 484
PRT+QSEETRVWHRRDGKWQ VHFH SGAP
Sbjct: 458 PRTSQSEETRVWHRRDGKWQNVHFHCSGAP 487
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 606 bits (1563), Expect = e-173
Identities = 308/405 (76%), Positives = 331/405 (81%), Gaps = 52/405 (12%)
Query: 3 TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62
T+TCTRFT+EYQL+E++GKGAFSVVRRCVK+ G EYAAKIINTKKLSARDHQKLEREAR
Sbjct: 4 TVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREAR 63
Query: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122
ICRLLKH NIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCIQQILEA
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 123
Query: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182
VLHCHQMGVVHRDLKPENLLLASK KGAAVKLADFGLAIEV+G+QQAWFGFAGTPGYLSP
Sbjct: 124 VLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSP 183
Query: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242
EVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 184 EVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
Query: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302
EAK+LIN+MLTINP+KRITA EALKHPW+ RSTVAS MHRQETV+CLKKFNARRKLKGA
Sbjct: 244 EAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGA 303
Query: 303 ILTTMLATRNFSGG------------------------KSGGNKKSDGVKKRKSSSSVQ- 337
ILTTMLATRNFS G KS NKK+DGVK + +S+
Sbjct: 304 ILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSA 363
Query: 338 ---------------------------LMESSESTNTTIEDEDTK 355
+ ESS+S NTTIEDED K
Sbjct: 364 AATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAK 408
Score = 231 bits (589), Expect = 1e-60
Identities = 102/131 (77%), Positives = 121/131 (92%)
Query: 354 TKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENL 413
T RKQEIIK TEQLIEA++NGDFE+Y K+CDPG+T+FEPEALGNLVEG+DFHRFYFENL
Sbjct: 531 TPSRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENL 590
Query: 414 WSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKW 473
++NSKP+HTTILNPH+H++G+++ACIAYIR+TQY+D G PRT+QSEETRVWHRRDGKW
Sbjct: 591 LAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 650
Query: 474 QIVHFHRSGAP 484
Q VHFH SGAP
Sbjct: 651 QNVHFHCSGAP 661
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 277 bits (708), Expect = 2e-74
Identities = 141/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSAR---DHQKLEREARICR 65
F + Y+L E +GKG FSVVRRC+ GQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 66 LLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 121
+LKHP+IV L ++ S +G Y++F+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
AKDL+ +ML ++P++RIT EAL HPW+ R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 302 AILTTM 307
A+L +
Sbjct: 307 AVLAAV 312
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 277 bits (708), Expect = 2e-74
Identities = 141/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSAR---DHQKLEREARICR 65
F + Y+L E +GKG FSVVRRC+ GQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 66 LLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 121
+LKHP+IV L ++ S +G Y++F+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
AKDL+ +ML ++P++RIT EAL HPW+ R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 302 AILTTM 307
A+L +
Sbjct: 307 AVLAAV 312
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 277 bits (708), Expect = 2e-74
Identities = 141/306 (46%), Positives = 203/306 (66%), Gaps = 8/306 (2%)
Query: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSAR---DHQKLEREARICR 65
F + Y+L E +GKG FSVVRRC+ GQ++A KI++ K ++ + L+REA IC
Sbjct: 8 FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67
Query: 66 LLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVARE----YYSEADASHCIQQILE 121
+LKHP+IV L ++ S +G Y++F+ + G +L +IV R YSEA ASH ++QILE
Sbjct: 68 MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
A+ +CH ++HRD+KP +LLASK A VKL FG+AI++ G GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 182 PEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVT 241
PEV++++PYGKPVD+W CGVIL+ILL G PF+ + RL++ I G Y +W ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246
Query: 242 PEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKG 301
AKDL+ +ML ++P++RIT EAL HPW+ R A +H ETV+ L+KFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306
Query: 302 AILTTM 307
A+L +
Sbjct: 307 AVLAAV 312
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 243 bits (621), Expect = 2e-64
Identities = 125/294 (42%), Positives = 182/294 (61%), Gaps = 3/294 (1%)
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
++ E LG GAFS V + G+ +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
V L D H YL+ LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKPENLL S+ + + + ++DFGL+ ++EG+ GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 193 PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 252
VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 253 TINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTT 306
+P+KR T +A +HPWI+ + + +H + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 243 bits (621), Expect = 2e-64
Identities = 125/294 (42%), Positives = 182/294 (61%), Gaps = 3/294 (1%)
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
++ E LG GAFS V + G+ +A K I K L ++ +E E + R +KH NI
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
V L D H YL+ LV+GGELF+ IV + +Y+E DAS I+Q+L+AV + H+MG+V
Sbjct: 82 VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKPENLL S+ + + + ++DFGL+ ++EG+ GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200
Query: 193 PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 252
VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260
Query: 253 TINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTT 306
+P+KR T +A +HPWI+ + + +H + K F A+ K + A T
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNF-AKSKWRQAFNAT 313
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 242 bits (617), Expect = 6e-64
Identities = 144/378 (38%), Positives = 216/378 (57%), Gaps = 24/378 (6%)
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
+++ ELG+GA S+V RC + + YA K++ D + + E + L HPNI
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSHPNI 101
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
++L + L+ +LVTGGELF+ IV + YYSE DA+ ++QILEAV + H+ G+V
Sbjct: 102 IKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIV 161
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKPENLL A+ A +K+ADFGL+ VE Q GTPGY +PE+LR YG
Sbjct: 162 HRDLKPENLLYATPAPDAPLKIADFGLSKIVE-HQVLMKTVCGTPGYCAPEILRGCAYGP 220
Query: 193 PVDLWACGVILYILLVGYPPFWDE--DQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250
VD+W+ G+I YILL G+ PF+DE DQ ++++I Y F SP WD V+ AKDL+ K
Sbjct: 221 EVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDLVRK 279
Query: 251 MLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLAT 310
++ ++P KR+T +AL+HPW++ ++ A+ +H L++FNARRKLK A+ + ++
Sbjct: 280 LIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVVASS 337
Query: 311 RNFSGGKSGGNKKSDGVKKRKSSSSVQLMESSESTNTTIEDED---------TKVRKQEI 361
R S S G+ + R S + + +E E E K + E+
Sbjct: 338 RLGSASSSHGSIQESHKASRDPS---PIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAEL 394
Query: 362 IKVTEQLIEAISNGDFES 379
+KV Q +E + D +
Sbjct: 395 MKV--QALEKVKGADINA 410
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 232 bits (592), Expect = 5e-61
Identities = 126/294 (42%), Positives = 176/294 (59%), Gaps = 3/294 (1%)
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
Y + LG GAFS V + A K I + L ++ +E E + +KHPNI
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHPNI 78
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
V L D GH YLI LV+GGELF+ IV + +Y+E DAS I Q+L+AV + H +G+V
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIV 138
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
HRDLKPENLL S + + + ++DFGL+ ++E GTPGY++PEVL + PY K
Sbjct: 139 HRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPYSK 197
Query: 193 PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 252
VD W+ GVI YILL GYPPF+DE+ +L++QI Y+F SP WD ++ AKD I ++
Sbjct: 198 AVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLM 257
Query: 253 TINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTT 306
+P KR T +AL+HPWI+ + + +H Q + +KK A+ K K A T
Sbjct: 258 EKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNAT 310
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 231 bits (588), Expect = 1e-60
Identities = 124/288 (43%), Positives = 174/288 (60%), Gaps = 6/288 (2%)
Query: 7 TRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRL 66
T + + E LG GAFS V + L G+ +A K I KK A LE E + +
Sbjct: 17 TNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCI--KKSPAFRDSSLENEIAVLKK 74
Query: 67 LKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHC 126
+KH NIV L D H+YL+ LV+GGELF+ I+ R Y+E DAS IQQ+L AV +
Sbjct: 75 IKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYL 134
Query: 127 HQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GTPGYLSPEVL 185
H+ G+VHRDLKPENLL + + + + + DFGL+ + EQ A GTPGY++PEVL
Sbjct: 135 HENGIVHRDLKPENLLYLTPEENSKIMITDFGLS---KMEQNGIMSTACGTPGYVAPEVL 191
Query: 186 RKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAK 245
+ PY K VD W+ GVI YILL GYPPF++E + +L+++IK G Y+F SP WD ++ AK
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 246 DLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKF 293
D I +L +P++R T +AL HPWI + + ++ ++ K F
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNF 299
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 230 bits (586), Expect = 3e-60
Identities = 122/261 (46%), Positives = 162/261 (62%), Gaps = 5/261 (1%)
Query: 13 YQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 72
Y++ E LG GAFS V + + A K I K L ++ +E E + R + HPNI
Sbjct: 32 YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90
Query: 73 VRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVV 132
V L D H YL +LVTGGELF+ I+ R Y+E DASH + Q+L AV + H +G+V
Sbjct: 91 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150
Query: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GTPGYLSPEVLRKDPYG 191
HRDLKPENLL A+ + + + ++DFGL+ G G A GTPGY++PE+L + PYG
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207
Query: 192 KPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKM 251
K VD+WA GVI YILL GYPPF+DE L+ QI +Y+F SP WD ++ AKD I +
Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267
Query: 252 LTINPSKRITAAEALKHPWIS 272
L +P KR T +AL+H WIS
Sbjct: 268 LERDPQKRFTCQQALRHLWIS 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,122,624
Number of Sequences: 37866
Number of extensions: 862087
Number of successful extensions: 5053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 572
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 2635
Number of HSP's gapped (non-prelim): 1040
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.