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Search of human proteins with 25952111
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25952111 tumor necrosis factor alpha [Homo sapiens]
(233 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25952111 tumor necrosis factor alpha [Homo sapiens] 464 e-131
gi|6806893 lymphotoxin alpha precursor [Homo sapiens] 85 5e-17
gi|229092381 lymphotoxin alpha precursor [Homo sapiens] 85 5e-17
gi|23510445 tumor necrosis factor (ligand) superfamily, member 1... 81 7e-16
gi|4557329 fas ligand [Homo sapiens] 68 8e-12
gi|25952144 tumor necrosis factor ligand superfamily, member 14 ... 67 1e-11
gi|25952147 tumor necrosis factor ligand superfamily, member 14 ... 67 2e-11
gi|4505035 lymphotoxin-beta isoform a [Homo sapiens] 64 8e-11
gi|14790152 tumor necrosis factor ligand superfamily, member 11 ... 48 6e-06
gi|4507595 tumor necrosis factor ligand superfamily, member 11 i... 48 6e-06
gi|4557433 CD40 ligand [Homo sapiens] 47 2e-05
gi|4507593 tumor necrosis factor (ligand) superfamily, member 10... 45 5e-05
gi|224548983 tumor necrosis factor superfamily, member 13b isofo... 41 0.001
gi|26051246 tumor necrosis factor ligand superfamily, member 13 ... 37 0.014
gi|4507599 tumor necrosis factor ligand superfamily, member 13 i... 37 0.014
gi|26051248 tumor necrosis factor ligand superfamily, member 13 ... 37 0.014
gi|26051250 TNFSF12-TNFSF13 protein [Homo sapiens] 37 0.014
gi|5730097 tumor necrosis factor superfamily, member 13b isoform... 36 0.025
gi|239756643 PREDICTED: hypothetical protein [Homo sapiens] 30 2.3
gi|239751132 PREDICTED: hypothetical protein [Homo sapiens] 30 2.3
gi|239745624 PREDICTED: hypothetical protein XP_002344159 [Homo ... 30 2.3
gi|4507607 tumor necrosis factor (ligand) superfamily, member 8 ... 29 3.0
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 29 3.9
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 29 3.9
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 28 8.8
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 28 8.8
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 28 8.8
>gi|25952111 tumor necrosis factor alpha [Homo sapiens]
Length = 233
Score = 464 bits (1193), Expect = e-131
Identities = 233/233 (100%), Positives = 233/233 (100%)
Query: 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR 60
MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
Sbjct: 1 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR 60
Query: 61 EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR 120
EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
Sbjct: 61 EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR 120
Query: 121 DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE 180
DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
Sbjct: 121 DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE 180
Query: 181 TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Sbjct: 181 TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
>gi|6806893 lymphotoxin alpha precursor [Homo sapiens]
Length = 205
Score = 85.1 bits (209), Expect = 5e-17
Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 87 KPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQG-- 144
KP AH++ +P + L W A L +G L +N L+VP+ G+Y +YSQV+F G+
Sbjct: 62 KPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYS 121
Query: 145 --CPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQL 202
S+ + L H + + Y V LLS+ Q+ G + +PW +Y G FQL
Sbjct: 122 PKATSSPLYLAHEVQLFSSQYPFHVPLLSS-----QKMVYPGLQ-EPWLHSMYHGAAFQL 175
Query: 203 EKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
+GD+LS + +L + S V+FG AL
Sbjct: 176 TQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL 205
>gi|229092381 lymphotoxin alpha precursor [Homo sapiens]
Length = 205
Score = 85.1 bits (209), Expect = 5e-17
Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 87 KPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQG-- 144
KP AH++ +P + L W A L +G L +N L+VP+ G+Y +YSQV+F G+
Sbjct: 62 KPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYS 121
Query: 145 --CPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQL 202
S+ + L H + + Y V LLS+ Q+ G + +PW +Y G FQL
Sbjct: 122 PKATSSPLYLAHEVQLFSSQYPFHVPLLSS-----QKMVYPGLQ-EPWLHSMYHGAAFQL 175
Query: 203 EKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
+GD+LS + +L + S V+FG AL
Sbjct: 176 TQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL 205
>gi|23510445 tumor necrosis factor (ligand) superfamily, member 15
[Homo sapiens]
Length = 251
Score = 81.3 bits (199), Expect = 7e-16
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 25/181 (13%)
Query: 71 SPLAQAVRSSSRTPSDKPVAHVVANPQAEGQ--------LQWLNRRANALLANGVELRDN 122
+P Q V + R DKP AH+ Q Q L W + A N + +
Sbjct: 78 APSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNK 137
Query: 123 QLVVPSEGLYLIYSQVLFKGQ----------GCPSTHVLLTHTISRIAVSYQTKVNLLSA 172
L++P G Y IYSQV F+G G P+ +T I+++ SY LL
Sbjct: 138 FLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMG 197
Query: 173 IKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIA 232
KS C+ W++PIYLG +F L++GD+L ++ +D+ + + +FG
Sbjct: 198 TKSVCE-------VGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFL 250
Query: 233 L 233
L
Sbjct: 251 L 251
>gi|4557329 fas ligand [Homo sapiens]
Length = 281
Score = 67.8 bits (164), Expect = 8e-12
Identities = 61/223 (27%), Positives = 93/223 (41%), Gaps = 18/223 (8%)
Query: 18 PKKTGGPQGSRRCLFLSLFSFLI--VAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQ 75
P K G + CL + F L+ V +F L H + E + S L +
Sbjct: 70 PLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQMHTASSLEK 129
Query: 76 AVRSSSRTPSDKP---VAHVVANPQAEGQ-LQWLNRRANALLANGVELRDNQLVVPSEGL 131
+ S P K VAH+ + L+W + LL+ GV+ + LV+ GL
Sbjct: 130 QIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLS-GVKYKKGGLVINETGL 188
Query: 132 YLIYSQVLFKGQGCPSTHVLLTHTISRIAVSY-QTKVNLLSAIKSPCQRETPEGAEAKPW 190
Y +YS+V F+GQ C ++ L+H + Y Q V + + S C + W
Sbjct: 189 YFVYSKVYFRGQSC--NNLPLSHKVYMRNSKYPQDLVMMEGKMMSYC-------TTGQMW 239
Query: 191 YEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
YLG VF L D L ++ ++F ES Q +FG+ L
Sbjct: 240 ARSSYLGAVFNLTSADHLYVNVSELSLVNFEES-QTFFGLYKL 281
>gi|25952144 tumor necrosis factor ligand superfamily, member 14
isoform 1 precursor [Homo sapiens]
Length = 240
Score = 67.4 bits (163), Expect = 1e-11
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 9/153 (5%)
Query: 82 RTPSDKPVAHVV-ANPQAEGQ---LQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQ 137
R+ P AH+ AN G L W + A L G+ D LVV G Y IYS+
Sbjct: 88 RSHEVNPAAHLTGANSSLTGSGGPLLWETQLGLAFL-RGLSYHDGALVVTKAGYYYIYSK 146
Query: 138 VLFKGQGCP-STHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYL 196
V G GCP +TH + + Y ++ LL + +SPC R T + ++ W++ +L
Sbjct: 147 VQLGGVGCPLGLASTITHGLYKRTPRYPEELELLVSQQSPCGRAT---SSSRVWWDSSFL 203
Query: 197 GGVFQLEKGDRLSAEINRPDYLDFAESGQVYFG 229
GGV LE G+++ + + + + YFG
Sbjct: 204 GGVVHLEAGEKVVVRVLDERLVRLRDGTRSYFG 236
>gi|25952147 tumor necrosis factor ligand superfamily, member 14
isoform 2 [Homo sapiens]
Length = 204
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/153 (30%), Positives = 71/153 (46%), Gaps = 9/153 (5%)
Query: 82 RTPSDKPVAHVV-ANPQAEGQ---LQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQ 137
R+ P AH+ AN G L W + A L G+ D LVV G Y IYS+
Sbjct: 52 RSHEVNPAAHLTGANSSLTGSGGPLLWETQLGLAFL-RGLSYHDGALVVTKAGYYYIYSK 110
Query: 138 VLFKGQGCP-STHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYL 196
V G GCP +TH + + Y ++ LL + +SPC R T + ++ W++ +L
Sbjct: 111 VQLGGVGCPLGLASTITHGLYKRTPRYPEELELLVSQQSPCGRAT---SSSRVWWDSSFL 167
Query: 197 GGVFQLEKGDRLSAEINRPDYLDFAESGQVYFG 229
GGV LE G+ + + + + + YFG
Sbjct: 168 GGVVHLEAGEEVVVRVLDERLVRLRDGTRSYFG 200
>gi|4505035 lymphotoxin-beta isoform a [Homo sapiens]
Length = 244
Score = 64.3 bits (155), Expect = 8e-11
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 20/159 (12%)
Query: 88 PVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQ-LVVPSEGLYLIYSQVLFKGQGCP 146
P AH++ P L W + A L +G + D + L +P +GLY +Y V ++G+ P
Sbjct: 88 PAAHLIGAPLKGQGLGWETTKEQAFLTSGTQFSDAEGLALPQDGLYYLYCLVGYRGRAPP 147
Query: 147 S------THVLLTHTISRIAVSYQTKV--------NLLSAIKSPCQRETPEGAEAKPWYE 192
V L ++ R +Y ++ + P +R+ WY
Sbjct: 148 GGGDPQGRSVTLRSSLYRAGGAYGPGTPELLLEGAETVTPVLDPARRQ----GYGPLWYT 203
Query: 193 PIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGII 231
+ GG+ QL +G+R+ I+ PD +DFA G+ +FG +
Sbjct: 204 SVGFGGLVQLRRGERVYVNISHPDMVDFAR-GKTFFGAV 241
>gi|14790152 tumor necrosis factor ligand superfamily, member 11
isoform 2 [Homo sapiens]
Length = 244
Score = 48.1 bits (113), Expect = 6e-06
Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 24/157 (15%)
Query: 87 KPVAHVVAN----PQAEGQLQ---WLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVL 139
+P AH+ N P ++ W + R A ++N + + +L+V +G Y +Y+ +
Sbjct: 90 QPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISN-MTFSNGKLIVNQDGFYYLYANIC 148
Query: 140 FKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPW-------YE 192
F+ ++ L T + + Y TK ++IK P +G K W +
Sbjct: 149 FRHH--ETSGDLATEYLQLMV--YVTK----TSIKIPSSHTLMKGGSTKYWSGNSEFHFY 200
Query: 193 PIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFG 229
I +GG F+L G+ +S E++ P LD + YFG
Sbjct: 201 SINVGGFFKLRSGEEISIEVSNPSLLD-PDQDATYFG 236
>gi|4507595 tumor necrosis factor ligand superfamily, member 11
isoform 1 [Homo sapiens]
Length = 317
Score = 48.1 bits (113), Expect = 6e-06
Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 24/157 (15%)
Query: 87 KPVAHVVAN----PQAEGQLQ---WLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVL 139
+P AH+ N P ++ W + R A ++N + + +L+V +G Y +Y+ +
Sbjct: 163 QPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISN-MTFSNGKLIVNQDGFYYLYANIC 221
Query: 140 FKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPW-------YE 192
F+ ++ L T + + Y TK ++IK P +G K W +
Sbjct: 222 FRHH--ETSGDLATEYLQLMV--YVTK----TSIKIPSSHTLMKGGSTKYWSGNSEFHFY 273
Query: 193 PIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFG 229
I +GG F+L G+ +S E++ P LD + YFG
Sbjct: 274 SINVGGFFKLRSGEEISIEVSNPSLLD-PDQDATYFG 309
>gi|4557433 CD40 ligand [Homo sapiens]
Length = 261
Score = 46.6 bits (109), Expect = 2e-05
Identities = 54/197 (27%), Positives = 80/197 (40%), Gaps = 29/197 (14%)
Query: 50 LLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKP---VAHVV--ANPQAEGQLQW 104
LL+ I Q E F +D+ L + S D+ AHV+ A+ + LQW
Sbjct: 81 LLNCEEIKSQFEGFVKDIMLNKEETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQW 140
Query: 105 LNRRANALLANGVELRDN-QLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSY 163
+ + N V L + QL V +GLY IY+QV F S S
Sbjct: 141 AEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTF---------------CSNREASS 185
Query: 164 QTKVNLLSAIKSPCQ------RETPEGAEAKP-WYEPIYLGGVFQLEKGDRLSAEINRPD 216
Q +KSP + R + AKP + I+LGGVF+L+ G + + P
Sbjct: 186 QAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPS 245
Query: 217 YLDFAESGQVYFGIIAL 233
+ +G FG++ L
Sbjct: 246 QVSHG-TGFTSFGLLKL 261
>gi|4507593 tumor necrosis factor (ligand) superfamily, member 10
[Homo sapiens]
Length = 281
Score = 45.1 bits (105), Expect = 5e-05
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Query: 104 WLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSY 163
W + R+ + + LR+ +LV+ +G Y IYSQ F+ Q + + + Y
Sbjct: 154 WESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKY 213
Query: 164 QTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAES 223
+ + + +KS R + +A+ IY GG+F+L++ DR+ + +D
Sbjct: 214 TSYPDPILLMKS--ARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHE 271
Query: 224 GQVYFG 229
+FG
Sbjct: 272 AS-FFG 276
>gi|224548983 tumor necrosis factor superfamily, member 13b isoform
2 [Homo sapiens]
Length = 266
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/167 (20%), Positives = 71/167 (42%), Gaps = 13/167 (7%)
Query: 67 LSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVV 126
L + P A +SS+ +K V P+ G ++ + + +E ++N+++V
Sbjct: 112 LKIFEPPAPGEGNSSQNSRNK---RAVQGPEETGSYTFVPWLLSFKRGSALEEKENKILV 168
Query: 127 PSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAE 186
G + IY QVL+ + H++ + + +++L++ + C + PE
Sbjct: 169 KETGYFFIYGQVLYTDKTYAMGHLIQRKKVH----VFGDELSLVTLFR--CIQNMPETLP 222
Query: 187 AKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
Y G+ +LE+GD L I R + + +FG + L
Sbjct: 223 NNSCYS----AGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKL 265
>gi|26051246 tumor necrosis factor ligand superfamily, member 13
isoform beta proprotein [Homo sapiens]
Length = 234
Score = 37.0 bits (84), Expect = 0.014
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 19/108 (17%)
Query: 107 RRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTK 166
RR L A G +R + G+YL+YSQVLF+ +T T+ ++ VS + +
Sbjct: 127 RRGRGLQAQGYGVR-----IQDAGVYLLYSQVLFQD---------VTFTMGQV-VSREGQ 171
Query: 167 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINR 214
+ + C R P + Y Y GVF L +GD LS I R
Sbjct: 172 GRQETLFR--CIRSMPSHPDRA--YNSCYSAGVFHLHQGDILSVIIPR 215
>gi|4507599 tumor necrosis factor ligand superfamily, member 13
isoform alpha proprotein [Homo sapiens]
Length = 250
Score = 37.0 bits (84), Expect = 0.014
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 19/108 (17%)
Query: 107 RRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTK 166
RR L A G +R + G+YL+YSQVLF+ +T T+ ++ VS + +
Sbjct: 143 RRGRGLQAQGYGVR-----IQDAGVYLLYSQVLFQD---------VTFTMGQV-VSREGQ 187
Query: 167 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINR 214
+ + C R P + Y Y GVF L +GD LS I R
Sbjct: 188 GRQETLFR--CIRSMPSHPDRA--YNSCYSAGVFHLHQGDILSVIIPR 231
>gi|26051248 tumor necrosis factor ligand superfamily, member 13
isoform gamma proprotein [Homo sapiens]
Length = 247
Score = 37.0 bits (84), Expect = 0.014
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 19/108 (17%)
Query: 107 RRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTK 166
RR L A G +R + G+YL+YSQVLF+ +T T+ ++ VS + +
Sbjct: 143 RRGRGLQAQGYGVR-----IQDAGVYLLYSQVLFQD---------VTFTMGQV-VSREGQ 187
Query: 167 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINR 214
+ + C R P + Y Y GVF L +GD LS I R
Sbjct: 188 GRQETLFR--CIRSMPSHPDRA--YNSCYSAGVFHLHQGDILSVIIPR 231
>gi|26051250 TNFSF12-TNFSF13 protein [Homo sapiens]
Length = 330
Score = 37.0 bits (84), Expect = 0.014
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 19/108 (17%)
Query: 107 RRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTK 166
RR L A G +R + G+YL+YSQVLF+ +T T+ ++ VS + +
Sbjct: 223 RRGRGLQAQGYGVR-----IQDAGVYLLYSQVLFQD---------VTFTMGQV-VSREGQ 267
Query: 167 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINR 214
+ + C R P + Y Y GVF L +GD LS I R
Sbjct: 268 GRQETLFR--CIRSMPSHPDRA--YNSCYSAGVFHLHQGDILSVIIPR 311
>gi|5730097 tumor necrosis factor superfamily, member 13b isoform 1
[Homo sapiens]
Length = 285
Score = 36.2 bits (82), Expect = 0.025
Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query: 115 NGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIK 174
+ +E ++N+++V G + IY QVL+ + H++ + + +++L++ +
Sbjct: 176 SALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVH----VFGDELSLVTLFR 231
Query: 175 SPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL 233
C + PE Y G+ +LE+GD L I R + + +FG + L
Sbjct: 232 --CIQNMPETLPNNSCYS----AGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKL 284
>gi|239756643 PREDICTED: hypothetical protein [Homo sapiens]
Length = 165
Score = 29.6 bits (65), Expect = 2.3
Identities = 12/34 (35%), Positives = 21/34 (61%)
Query: 157 SRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPW 190
+R+ + Q +++L AI + QR+T G A+PW
Sbjct: 34 TRLYAARQASLSILVAIAAEPQRDTVRGGRARPW 67
>gi|239751132 PREDICTED: hypothetical protein [Homo sapiens]
Length = 118
Score = 29.6 bits (65), Expect = 2.3
Identities = 12/34 (35%), Positives = 21/34 (61%)
Query: 157 SRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPW 190
+R+ + Q +++L AI + QR+T G A+PW
Sbjct: 21 TRLYAARQASLSILVAIAAEPQRDTVRGGRARPW 54
>gi|239745624 PREDICTED: hypothetical protein XP_002344159 [Homo
sapiens]
Length = 165
Score = 29.6 bits (65), Expect = 2.3
Identities = 12/34 (35%), Positives = 21/34 (61%)
Query: 157 SRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPW 190
+R+ + Q +++L AI + QR+T G A+PW
Sbjct: 34 TRLYAARQASLSILVAIAAEPQRDTVRGGRARPW 67
>gi|4507607 tumor necrosis factor (ligand) superfamily, member 8
[Homo sapiens]
Length = 234
Score = 29.3 bits (64), Expect = 3.0
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 82 RTPSDKPVAHV-VANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLF 140
R P K A++ VA + +L W N+ + +GV +D LV+ GLY I Q+ F
Sbjct: 92 RAPFKKSWAYLQVAKHLNKTKLSW-NKDG---ILHGVRYQDGNLVIQFPGLYFIICQLQF 147
Query: 141 KGQGCPSTHV 150
Q CP+ V
Sbjct: 148 LVQ-CPNNSV 156
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 28.9 bits (63), Expect = 3.9
Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 66 DLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLV 125
+L+++ L Q+ S P + ++ +NP+ + QL+ LN+ +AL + +D++ +
Sbjct: 1115 ELAVLLNLLQSQTDLS-IPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETM 1173
Query: 126 VPSEGL 131
P E L
Sbjct: 1174 APEESL 1179
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 28.9 bits (63), Expect = 3.9
Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 66 DLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLV 125
+L+++ L Q+ S P + ++ +NP+ + QL+ LN+ +AL + +D++ +
Sbjct: 1115 ELAVLLNLLQSQTDLS-IPQMAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETM 1173
Query: 126 VPSEGL 131
P E L
Sbjct: 1174 APEESL 1179
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 27.7 bits (60), Expect = 8.8
Identities = 39/145 (26%), Positives = 56/145 (38%), Gaps = 14/145 (9%)
Query: 64 PRDLSLISPLAQAVRSSSRTPSDKPVAH---VVANPQAEGQL-QWLNRRANALLANGVEL 119
PR S IS L+ S+SRT D P H V + ++G L + ++ AN EL
Sbjct: 1016 PRSPSPISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISEL 1075
Query: 120 RDNQLVV----PSEGLYLIYSQVLFKGQGCPSTHVLLT--HTISRIAVSYQTKVNLLSAI 173
L P G L S ++ K P+T + I V+ + +
Sbjct: 1076 NSMMLSTAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQA 1135
Query: 174 KSPCQRET----PEGAEAKPWYEPI 194
RE+ PE A AKP E +
Sbjct: 1136 AGDAARESPAAGPEAAAAKPDLEEL 1160
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 27.7 bits (60), Expect = 8.8
Identities = 39/145 (26%), Positives = 56/145 (38%), Gaps = 14/145 (9%)
Query: 64 PRDLSLISPLAQAVRSSSRTPSDKPVAH---VVANPQAEGQL-QWLNRRANALLANGVEL 119
PR S IS L+ S+SRT D P H V + ++G L + ++ AN EL
Sbjct: 984 PRSPSPISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISEL 1043
Query: 120 RDNQLVV----PSEGLYLIYSQVLFKGQGCPSTHVLLT--HTISRIAVSYQTKVNLLSAI 173
L P G L S ++ K P+T + I V+ + +
Sbjct: 1044 NSMMLSTAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQA 1103
Query: 174 KSPCQRET----PEGAEAKPWYEPI 194
RE+ PE A AKP E +
Sbjct: 1104 AGDAARESPAAGPEAAAAKPDLEEL 1128
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 27.7 bits (60), Expect = 8.8
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 16 ALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISP-LA 74
ALP++ G G+ + + + + L+ A L C LHFG G R RDL+ P ++
Sbjct: 418 ALPQENGLSPGAIAGIVIGVVA-LVALIAVALACFLHFGKTG--RASDQRDLTEHKPSVS 474
Query: 75 QAVRSSSRTPSDK 87
+ S P +K
Sbjct: 475 NHTQDHSNDPPNK 487
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,743,494
Number of Sequences: 37866
Number of extensions: 381320
Number of successful extensions: 841
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 802
Number of HSP's gapped (non-prelim): 29
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.