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Search of human proteins with 25777677
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25777677 Ras association domain family 2 [Homo sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25777677 Ras association domain family 2 [Homo sapiens] 654 0.0
gi|7661964 Ras association domain family 2 [Homo sapiens] 654 0.0
gi|23510360 Ras association domain family 4 [Homo sapiens] 350 1e-96
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor... 229 2e-60
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor... 229 2e-60
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor... 73 3e-13
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor... 73 3e-13
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3... 68 1e-11
gi|25777684 Ras association domain family 1 isoform D [Homo sapi... 62 9e-10
gi|25777682 Ras association domain family 1 isoform C [Homo sapi... 62 9e-10
gi|20149588 Ras association domain family 1 isoform A [Homo sapi... 62 9e-10
gi|25777680 Ras association domain family 1 isoform B [Homo sapi... 62 9e-10
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 41 0.001
gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Hom... 38 0.011
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor... 33 0.26
gi|205277394 coenzyme A synthase isoform c [Homo sapiens] 33 0.34
gi|110227607 coenzyme A synthase isoform b [Homo sapiens] 33 0.34
gi|110227605 coenzyme A synthase isoform a [Homo sapiens] 33 0.34
gi|110227601 coenzyme A synthase isoform a [Homo sapiens] 33 0.34
gi|110227603 coenzyme A synthase isoform a [Homo sapiens] 33 0.34
gi|21361440 RAB3A interacting protein (rabin3)-like 1 [Homo sapi... 33 0.45
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 32 1.0
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 31 1.3
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 31 1.3
gi|148596992 heart alpha-kinase [Homo sapiens] 31 1.3
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 31 1.3
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 31 1.7
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 30 2.2
>gi|25777677 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 654 bits (1687), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW 60
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW
Sbjct: 1 MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW 60
Query: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ 120
GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ
Sbjct: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ 120
Query: 121 MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT 180
MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT
Sbjct: 121 MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT 180
Query: 181 SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY 240
SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY
Sbjct: 181 SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY 240
Query: 241 PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK
Sbjct: 241 PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
Query: 301 LMRKYTVLRLMIRQRLEEIAETPATI 326
LMRKYTVLRLMIRQRLEEIAETPATI
Sbjct: 301 LMRKYTVLRLMIRQRLEEIAETPATI 326
>gi|7661964 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 654 bits (1687), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW 60
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW
Sbjct: 1 MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW 60
Query: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ 120
GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ
Sbjct: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ 120
Query: 121 MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT 180
MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT
Sbjct: 121 MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT 180
Query: 181 SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY 240
SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY
Sbjct: 181 SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY 240
Query: 241 PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK
Sbjct: 241 PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
Query: 301 LMRKYTVLRLMIRQRLEEIAETPATI 326
LMRKYTVLRLMIRQRLEEIAETPATI
Sbjct: 301 LMRKYTVLRLMIRQRLEEIAETPATI 326
>gi|23510360 Ras association domain family 4 [Homo sapiens]
Length = 321
Score = 350 bits (898), Expect = 1e-96
Identities = 188/330 (56%), Positives = 232/330 (70%), Gaps = 33/330 (10%)
Query: 7 TSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPI 66
+S VP K I K+ELL LKTYN Y+EG++ QLRHREEE I+EGLLNI+WGLRRPI
Sbjct: 8 SSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPI 67
Query: 67 RLQMQDDNERIRPPPSSSSW---HSGC----------NLGAQGTTLKPLTVPKVQISEVD 113
RLQMQDD E++ P S+SW C N+ AQG +++P+
Sbjct: 68 RLQMQDDREQVHLP--STSWMPRRPSCPLKEPSPQNGNITAQGPSIQPV----------- 114
Query: 114 APPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGV--RRRGNVRTPSDQRRIRRHRFSI 171
+ SSTDS G E+ PQLMRT+SD +RR R P + +RIRRHRFSI
Sbjct: 115 -----HKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSI 169
Query: 172 NGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGE 231
NGHFYNHKTSVFTPAYGSVTNVR+NSTMTT QVL LLLNKF++E+ EFALY+VH SGE
Sbjct: 170 NGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGE 229
Query: 232 KQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQ 291
+ KLK +YPLI+RIL GPCE+I+++FLME D EV ++VAQYIKFEMPVL SF++KL+
Sbjct: 230 RTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLK 289
Query: 292 EEEDREVKKLMRKYTVLRLMIRQRLEEIAE 321
EEE+RE+ KL K+ LRL + QRLE++ E
Sbjct: 290 EEEEREIIKLTMKFQALRLTMLQRLEQLVE 319
>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
[Homo sapiens]
Length = 369
Score = 229 bits (585), Expect = 2e-60
Identities = 136/338 (40%), Positives = 215/338 (63%), Gaps = 20/338 (5%)
Query: 4 SHQ-TSLVPCGQDKYISKNELLLHLKTYNLYYEGQ-NLQLRHREEED-EFIVEGLLNISW 60
+HQ S + + +I++ +L LKTYN++YE Q NL + + E ED + IVEG+L+I W
Sbjct: 37 AHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFW 96
Query: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAP--PEG 118
G++RPI+L++QD+ +P S +S S ++G T +ISE+D P
Sbjct: 97 GVKRPIQLKIQDE----KPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 152
Query: 119 DQMPSSTD-----SRGLKPL---QEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFS 170
++ S D S LKP + D+P L RT S+ + R+ D++ +++R S
Sbjct: 153 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 212
Query: 171 INGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSG 230
INGHFYNH+TS+F PA+ S T VR+NS M T +V+K LL KFKIENS ++FAL+++ +G
Sbjct: 213 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 272
Query: 231 EKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKL 290
E+++LK TD PL+ R+LQGP E+ +++FLM+KD EE++ DVAQYI F +L+S +Q+L
Sbjct: 273 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLESILQRL 331
Query: 291 QEEEDREVKKLMRKYTVLRLMIRQRLEE--IAETPATI 326
EEE RE+++++ K+ + +I + L+ + +T T+
Sbjct: 332 NEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 369
>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
[Homo sapiens]
Length = 337
Score = 229 bits (585), Expect = 2e-60
Identities = 136/338 (40%), Positives = 215/338 (63%), Gaps = 20/338 (5%)
Query: 4 SHQ-TSLVPCGQDKYISKNELLLHLKTYNLYYEGQ-NLQLRHREEED-EFIVEGLLNISW 60
+HQ S + + +I++ +L LKTYN++YE Q NL + + E ED + IVEG+L+I W
Sbjct: 5 AHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFW 64
Query: 61 GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAP--PEG 118
G++RPI+L++QD+ +P S +S S ++G T +ISE+D P
Sbjct: 65 GVKRPIQLKIQDE----KPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMS 120
Query: 119 DQMPSSTD-----SRGLKPL---QEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFS 170
++ S D S LKP + D+P L RT S+ + R+ D++ +++R S
Sbjct: 121 EKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRAS 180
Query: 171 INGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSG 230
INGHFYNH+TS+F PA+ S T VR+NS M T +V+K LL KFKIENS ++FAL+++ +G
Sbjct: 181 INGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATG 240
Query: 231 EKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKL 290
E+++LK TD PL+ R+LQGP E+ +++FLM+KD EE++ DVAQYI F +L+S +Q+L
Sbjct: 241 EQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKD-AEEISSDVAQYINFHFSLLESILQRL 299
Query: 291 QEEEDREVKKLMRKYTVLRLMIRQRLEE--IAETPATI 326
EEE RE+++++ K+ + +I + L+ + +T T+
Sbjct: 300 NEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV 337
>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
[Homo sapiens]
Length = 265
Score = 73.2 bits (178), Expect = 3e-13
Identities = 44/148 (29%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 179 KTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEK--QKL 235
+TS + P ++ + I+ST T +V++ LL KF + ++ ++FAL+ +H G+ QKL
Sbjct: 124 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 182
Query: 236 KATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEED 295
D PL R+L GP ++ F++++++ EV +D F +P L++F+ L++EE
Sbjct: 183 SIADRPLYLRLLAGPDTEVLS-FVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQ 236
Query: 296 REVKKLMRKYTVLRLMIRQRLEEIAETP 323
+++++ +KY R + + L E P
Sbjct: 237 DKIQQVQKKYDKFRQKLEEALRESQGKP 264
>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
[Homo sapiens]
Length = 418
Score = 73.2 bits (178), Expect = 3e-13
Identities = 44/148 (29%), Positives = 85/148 (57%), Gaps = 10/148 (6%)
Query: 179 KTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEK--QKL 235
+TS + P ++ + I+ST T +V++ LL KF + ++ ++FAL+ +H G+ QKL
Sbjct: 277 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 335
Query: 236 KATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEED 295
D PL R+L GP ++ F++++++ EV +D F +P L++F+ L++EE
Sbjct: 336 SIADRPLYLRLLAGPDTEVLS-FVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQ 389
Query: 296 REVKKLMRKYTVLRLMIRQRLEEIAETP 323
+++++ +KY R + + L E P
Sbjct: 390 DKIQQVQKKYDKFRQKLEEALRESQGKP 417
>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
[Homo sapiens]
Length = 238
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
Query: 188 GSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEKQKLKATD--YPLIA 244
G + + I+ST T +V++ LL KF + S +FALY H + K +D +PL
Sbjct: 108 GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYL 167
Query: 245 RILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRK 304
R++ GP L E +++ ++ F +P L++F++ L +EED +++ L R+
Sbjct: 168 RLVAGPRTDTLSFVLRE--------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219
Query: 305 YTVLRLMIRQRLEEI 319
YT R + + L E+
Sbjct: 220 YTAYRQKLEEALREV 234
>gi|25777684 Ras association domain family 1 isoform D [Homo
sapiens]
Length = 344
Score = 61.6 bits (148), Expect = 9e-10
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229
G +TS + P +V ++ + S +V++ LL KF + + +FAL+ H
Sbjct: 199 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 257
Query: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289
+KL + PL R+L GP ++ L E D EV +D F MP L +F++
Sbjct: 258 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 311
Query: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316
LQ EE+ ++++++KY+ R I++ L
Sbjct: 312 LQREEEEHLRQILQKYSYCRQKIQEAL 338
>gi|25777682 Ras association domain family 1 isoform C [Homo
sapiens]
Length = 270
Score = 61.6 bits (148), Expect = 9e-10
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229
G +TS + P +V ++ + S +V++ LL KF + + +FAL+ H
Sbjct: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 183
Query: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289
+KL + PL R+L GP ++ L E D EV +D F MP L +F++
Sbjct: 184 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 237
Query: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316
LQ EE+ ++++++KY+ R I++ L
Sbjct: 238 LQREEEEHLRQILQKYSYCRQKIQEAL 264
>gi|20149588 Ras association domain family 1 isoform A [Homo
sapiens]
Length = 340
Score = 61.6 bits (148), Expect = 9e-10
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229
G +TS + P +V ++ + S +V++ LL KF + + +FAL+ H
Sbjct: 195 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 253
Query: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289
+KL + PL R+L GP ++ L E D EV +D F MP L +F++
Sbjct: 254 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 307
Query: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316
LQ EE+ ++++++KY+ R I++ L
Sbjct: 308 LQREEEEHLRQILQKYSYCRQKIQEAL 334
>gi|25777680 Ras association domain family 1 isoform B [Homo
sapiens]
Length = 189
Score = 61.6 bits (148), Expect = 9e-10
Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229
G +TS + P +V ++ + S +V++ LL KF + + +FAL+ H
Sbjct: 44 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 102
Query: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289
+KL + PL R+L GP ++ L E D EV +D F MP L +F++
Sbjct: 103 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 156
Query: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316
LQ EE+ ++++++KY+ R I++ L
Sbjct: 157 LQREEEEHLRQILQKYSYCRQKIQEAL 183
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/112 (26%), Positives = 60/112 (53%), Gaps = 5/112 (4%)
Query: 193 VRINSTMTTPQVLKLLLNKFKIEN---SAEEFALYVVHTSGEKQKLKATDYPLIARILQG 249
+R++ST TT V++ L KF+ + S+ +++LY VH SGE+ +L + PL+ ++
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118
Query: 250 PCEQISKVFLM-EKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
++ + L E D + + + V+++F + L ++E +E KK
Sbjct: 119 KDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKK 170
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/112 (26%), Positives = 60/112 (53%), Gaps = 5/112 (4%)
Query: 193 VRINSTMTTPQVLKLLLNKFKIEN---SAEEFALYVVHTSGEKQKLKATDYPLIARILQG 249
+R++ST TT V++ L KF+ + S+ +++LY VH SGE+ +L + PL+ ++
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118
Query: 250 PCEQISKVFLM-EKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK 300
++ + L E D + + + V+++F + L ++E +E KK
Sbjct: 119 KDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKK 170
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/115 (27%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 193 VRINSTMTTPQVLKLLLNKFKIEN---SAEEFALYVVHTSGEKQKLKATDYPLIARILQG 249
+R++ST TT V++ L KF+ + S+ +++LY VH SGE+ +L + PL+ ++
Sbjct: 60 IRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGER-RLDIDEKPLVVQLNWN 118
Query: 250 PCEQISKVFLMEKDQVEEVTYDVAQYIKFEMP----VLKSFIQKLQEEEDREVKK 300
++ + L K++ + + AQ E V+++F + L ++E +E KK
Sbjct: 119 KDDREGRFVL--KNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKK 171
>gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Homo
sapiens]
Length = 730
Score = 38.1 bits (87), Expect = 0.011
Identities = 32/136 (23%), Positives = 64/136 (47%), Gaps = 18/136 (13%)
Query: 139 QLMRTRSDVGVRRRGNVRTPSDQRRIRR--HRFSINGHFYNHKTSV------FTPAY--- 187
+L + +G+ RR V S Q++ + H+FS+ ++ H+ +V F Y
Sbjct: 342 ELKEFQKILGMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYITE 401
Query: 188 GSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARIL 247
S +V+ + ++LK++ K I+ + E+ AL + SGEK +L+ D ++
Sbjct: 402 HSYVSVKAKVSSIAQEILKVVAEK--IQYAEEDLALVAITFSGEKHELQPNDL-----VI 454
Query: 248 QGPCEQISKVFLMEKD 263
E ++++ KD
Sbjct: 455 SKSLEASGRIYVYRKD 470
>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
[Homo sapiens]
Length = 336
Score = 33.5 bits (75), Expect = 0.26
Identities = 17/54 (31%), Positives = 34/54 (62%), Gaps = 2/54 (3%)
Query: 179 KTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGE 231
+TS + P ++ + I+ST T +V++ LL KF + ++ ++FAL+ +H G+
Sbjct: 277 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQ 329
>gi|205277394 coenzyme A synthase isoform c [Homo sapiens]
Length = 593
Score = 33.1 bits (74), Expect = 0.34
Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Query: 207 LLLNKFKIENSAEEFALYVV-------HTSGEKQKLKATDY--PLIARILQGPCEQ 253
+ +N+F++EN EE ALY + HT E+ K+ ++ + ++ +L+ P E+
Sbjct: 325 MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYER 380
>gi|110227607 coenzyme A synthase isoform b [Homo sapiens]
Length = 269
Score = 33.1 bits (74), Expect = 0.34
Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Query: 207 LLLNKFKIENSAEEFALYVV-------HTSGEKQKLKATDY--PLIARILQGPCEQ 253
+ +N+F++EN EE ALY + HT E+ K+ ++ + ++ +L+ P E+
Sbjct: 1 MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYER 56
>gi|110227605 coenzyme A synthase isoform a [Homo sapiens]
Length = 564
Score = 33.1 bits (74), Expect = 0.34
Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Query: 207 LLLNKFKIENSAEEFALYVV-------HTSGEKQKLKATDY--PLIARILQGPCEQ 253
+ +N+F++EN EE ALY + HT E+ K+ ++ + ++ +L+ P E+
Sbjct: 296 MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYER 351
>gi|110227601 coenzyme A synthase isoform a [Homo sapiens]
Length = 564
Score = 33.1 bits (74), Expect = 0.34
Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Query: 207 LLLNKFKIENSAEEFALYVV-------HTSGEKQKLKATDY--PLIARILQGPCEQ 253
+ +N+F++EN EE ALY + HT E+ K+ ++ + ++ +L+ P E+
Sbjct: 296 MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYER 351
>gi|110227603 coenzyme A synthase isoform a [Homo sapiens]
Length = 564
Score = 33.1 bits (74), Expect = 0.34
Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 9/56 (16%)
Query: 207 LLLNKFKIENSAEEFALYVV-------HTSGEKQKLKATDY--PLIARILQGPCEQ 253
+ +N+F++EN EE ALY + HT E+ K+ ++ + ++ +L+ P E+
Sbjct: 296 MAINRFRLENDLEELALYQIQLLKDLRHTENEEDKVSSSSFRQRMLGNLLRPPYER 351
>gi|21361440 RAB3A interacting protein (rabin3)-like 1 [Homo
sapiens]
Length = 382
Score = 32.7 bits (73), Expect = 0.45
Identities = 29/125 (23%), Positives = 58/125 (46%), Gaps = 20/125 (16%)
Query: 204 VLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKD 263
VL+L + +I EF +H + ++ KLK + CE++SKV +
Sbjct: 61 VLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDEE-----------CERLSKVREQLEQ 109
Query: 264 QVEEVT---YDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEEIA 320
++EE+T ++ A + E + ++ +K +E ++ L + T L+ ++ I
Sbjct: 110 ELEELTASLFEEAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLV------IT 163
Query: 321 ETPAT 325
TPA+
Sbjct: 164 STPAS 168
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 31.6 bits (70), Expect = 1.0
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 10/107 (9%)
Query: 63 RRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLT-VPKVQISEVDAPPEGDQM 121
R P R + +R + S HS L +K + P SE D+ PE +
Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHS---LSGSSPGMKDIPRTPSRGRSECDSSPEPKAL 1489
Query: 122 PSSTDSRGLKPLQED------TPQLMRTRSDVGVRRRGNVRTPSDQR 162
P + R P + TPQ R+ S+ V ++ RTP QR
Sbjct: 1490 PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQR 1536
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 31.2 bits (69), Expect = 1.3
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 77 IRPPPSSSSWHSGCNLGAQGTTLKPLT-----VPKVQISEVDAPPEGDQMPSSTDSRGLK 131
++PPP ++ + L A KP +P+ Q + APP Q P ST ++GL
Sbjct: 396 VQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTP-STQAQGLP 454
Query: 132 PLQEDTPQ 139
+ TPQ
Sbjct: 455 AQAQATPQ 462
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 80 PPSSSSWHSGCNLGAQGT--TLKPLTVPKVQISEVDAPPEGDQMP---SSTDSRGLKPL- 133
PP + SG +GT T PL P E+ +PPE +MP SS +R PL
Sbjct: 577 PPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLP 636
Query: 134 -QEDTPQL 140
Q TP +
Sbjct: 637 NQRKTPPM 644
>gi|148596992 heart alpha-kinase [Homo sapiens]
Length = 2170
Score = 31.2 bits (69), Expect = 1.3
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
Query: 188 GSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARIL 247
G+VT+ I+ M P++ L + + K +S+ A + SGE++ KA ++L
Sbjct: 1616 GNVTDFLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKA------PKLL 1669
Query: 248 QGPCEQ 253
Q PC++
Sbjct: 1670 QDPCQK 1675
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 31.2 bits (69), Expect = 1.3
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 11/106 (10%)
Query: 213 KIENSAEEFALYVVHTSGEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDV 272
++ ++ L T G++++L L IL+ C+++ + ++ +V
Sbjct: 461 EVSKLTKQLMLLEAKTHGQEKELAENREQL--EILRAKCQEL------KTHSDGKIAVEV 512
Query: 273 AQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMIRQRLEE 318
+ I E LKS +QK +E+E E+++LM K TVL+ + L E
Sbjct: 513 HKSIVNE---LKSQLQKEEEKERAEMEELMEKLTVLQAQKKSLLLE 555
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 30.8 bits (68), Expect = 1.7
Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 21/128 (16%)
Query: 195 INSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDYPLIARILQGPCEQI 254
+N + QV KL + K ++ +E V S EK + +LQ E +
Sbjct: 741 LNKLLENEQVQKLFV-KTQLYGFLKEMGSEVSEDSEEKD---------VVNVLQAVGESL 790
Query: 255 SKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEE---EDREVKKLMRKYTVLRLM 311
+K+ E ++A ++ L+ I+ LQEE + E+K L+R Y +++
Sbjct: 791 AKI--------NEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVL 842
Query: 312 IRQRLEEI 319
+R+ LEEI
Sbjct: 843 LRKELEEI 850
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 30.4 bits (67), Expect = 2.2
Identities = 20/69 (28%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 253 QISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRKYTVLRLMI 312
Q+SK +K ++E VT A+ K E+ +LK + EE+D +++++ + + V+ M+
Sbjct: 784 QLSKETEEQKPKLERVTKQCAKLTK-EIRLLKDTKDETMEEQDIKLREMKQFHKVIDEML 842
Query: 313 RQRLEEIAE 321
+EE E
Sbjct: 843 VDIIEENTE 851
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,884,431
Number of Sequences: 37866
Number of extensions: 606253
Number of successful extensions: 2135
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2075
Number of HSP's gapped (non-prelim): 85
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.