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Search of human proteins with 25141323
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25141323 copine V [Homo sapiens]
(593 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25141323 copine V [Homo sapiens] 1201 0.0
gi|25121972 copine VIII [Homo sapiens] 939 0.0
gi|88703066 copine-like protein [Homo sapiens] 884 0.0
gi|4503015 copine III [Homo sapiens] 538 e-153
gi|30181236 copine II [Homo sapiens] 529 e-150
gi|18677733 copine IV [Homo sapiens] 515 e-146
gi|23397708 copine I isoform a [Homo sapiens] 510 e-144
gi|23397706 copine I isoform a [Homo sapiens] 510 e-144
gi|23397704 copine I isoform a [Homo sapiens] 510 e-144
gi|23397702 copine I isoform a [Homo sapiens] 510 e-144
gi|23397700 copine I isoform a [Homo sapiens] 510 e-144
gi|23397698 copine I isoform a [Homo sapiens] 510 e-144
gi|23397696 copine I isoform a [Homo sapiens] 510 e-144
gi|197333761 copine I isoform b [Homo sapiens] 510 e-144
gi|25141328 copine 7 isoform a [Homo sapiens] 489 e-138
gi|5174421 copine 6 [Homo sapiens] 482 e-136
gi|7656993 copine 7 isoform b [Homo sapiens] 474 e-133
gi|39752671 synaptotagmin X [Homo sapiens] 56 1e-07
gi|28376627 synaptotagmin IX [Homo sapiens] 55 1e-07
gi|13384594 protein kinase C, gamma [Homo sapiens] 54 4e-07
gi|209447073 synaptotagmin I [Homo sapiens] 52 2e-06
gi|5032139 synaptotagmin I [Homo sapiens] 52 2e-06
gi|209447070 synaptotagmin I [Homo sapiens] 52 2e-06
gi|4506067 protein kinase C, alpha [Homo sapiens] 51 3e-06
gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo... 51 3e-06
gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Hom... 51 3e-06
gi|45504376 synaptotagmin VI [Homo sapiens] 49 1e-05
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 47 5e-05
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 47 5e-05
gi|238550198 synaptotagmin III [Homo sapiens] 47 5e-05
>gi|25141323 copine V [Homo sapiens]
Length = 593
Score = 1201 bits (3106), Expect = 0.0
Identities = 593/593 (100%), Positives = 593/593 (100%)
Query: 1 MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWR 60
MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWR
Sbjct: 1 MEQPEDMASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWR 60
Query: 61 EFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLG 120
EFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLG
Sbjct: 61 EFGRTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLG 120
Query: 121 EIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVAT 180
EIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVAT
Sbjct: 121 EIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVAT 180
Query: 181 MQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALC 240
MQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALC
Sbjct: 181 MQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALC 240
Query: 241 NGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVN 300
NGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVN
Sbjct: 241 NGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVN 300
Query: 301 SGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYA 360
SGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYA
Sbjct: 301 SGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYA 360
Query: 361 LALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYH 420
LALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYH
Sbjct: 361 LALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYH 420
Query: 421 RSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAK 480
RSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAK
Sbjct: 421 RSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAK 480
Query: 481 LPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMA 540
LPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMA
Sbjct: 481 LPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMA 540
Query: 541 RLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI 593
RLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI
Sbjct: 541 RLARDVLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI 593
>gi|25121972 copine VIII [Homo sapiens]
Length = 564
Score = 939 bits (2427), Expect = 0.0
Identities = 455/586 (77%), Positives = 511/586 (87%), Gaps = 30/586 (5%)
Query: 8 ASLSEFDSLAGSIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEV 67
A + + + L+ +IPAT+VE++VSCRNLLD+D FSKSDP+CV+Y QG+ NK+WREFGRTEV
Sbjct: 9 AGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEV 68
Query: 68 IDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPG 127
IDNTLNPDFVRKFI+DYFFEE++NLRFDLYDVDSKSP+LSKHDFLGQ FCTLGEIVGS G
Sbjct: 69 IDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQG 128
Query: 128 SRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANK 187
SRLEKP+ G+PGKKCGTIIL+AEEL+ CRD MQFCANK
Sbjct: 129 SRLEKPIV--------------------GIPGKKCGTIILTAEELNCCRDAVLMQFCANK 168
Query: 188 LDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRT 247
LDKKDFFGKSDPFLVFYRSNEDG+FTICHKTEV+KNTLNPVWQ F I VRALCNGDYDRT
Sbjct: 169 LDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRT 228
Query: 248 IKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLL 307
IKVEVYDWDRDGSHDFIGEFTTSYREL+RGQSQFN+YEVVNPKKK KKKKY NSGTVTLL
Sbjct: 229 IKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLL 288
Query: 308 SFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVG 367
SF VE+E +FLDYIKGGTQINFTVAIDFTASNGNP+Q TSLHYM+PYQLNAY +AL AVG
Sbjct: 289 SFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVG 348
Query: 368 EIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQ 427
EI+Q YDSDKMFPALGFGAKLPPDGR+SHEF LNGN +NP C GI+G++EAY+RSL++VQ
Sbjct: 349 EIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQ 408
Query: 428 LYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIII 487
LYGPTNFAPV+ HVAR A++V+DGSQY VLLI+TDGVISDMAQTKE+IVNA+KLPMSIII
Sbjct: 409 LYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIII 468
Query: 488 VGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVL 547
VGVG AEFDAMVELDGDDVR+SSRGK AERDIVQFVPFRDY+DR+GNH+LSMARLA+DVL
Sbjct: 469 VGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVL 528
Query: 548 AEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTPPASPLHTHI 593
AEIP+Q +SYM+A+GI+P P P P TPP L T I
Sbjct: 529 AEIPEQFLSYMRARGIKPSPAP----------PPYTPPTHVLQTQI 564
>gi|88703066 copine-like protein [Homo sapiens]
Length = 553
Score = 884 bits (2283), Expect = 0.0
Identities = 430/567 (75%), Positives = 490/567 (86%), Gaps = 23/567 (4%)
Query: 19 SIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVR 78
S+PATK+EITVSCRNLLD D FSKSDP+ V+YTQ +++WREFGRTEVIDNTLNPDFVR
Sbjct: 10 SVPATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVR 69
Query: 79 KFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGA 138
KF++DYFFEEKQNLRFD+Y+VDSK+ DFLGQAF LGE++G GSR+E+ LT
Sbjct: 70 KFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLT--- 126
Query: 139 FSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSD 198
GVPGKKCGTI+L+AEELSNCRD+ATMQ CANKLDKKDFFGKSD
Sbjct: 127 -----------------GVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSD 169
Query: 199 PFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD 258
PFLVFYRSNEDGTFTICHKTEV+KNTLNPVWQ FSIPVRALCNGDYDRT+K++VYDWDRD
Sbjct: 170 PFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRD 229
Query: 259 GSHDFIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFL 318
GSHDFIGEFTTSYREL++ Q+QF +YEV+NP+KK KKKKYVNSGTVTLLSF+V+SE TF+
Sbjct: 230 GSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFV 289
Query: 319 DYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKM 378
DYIKGGTQ+NFTVAIDFTASNGNP Q TSLHYMSPYQL+AYA+AL AVGEIIQ YDSDK+
Sbjct: 290 DYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKL 349
Query: 379 FPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVV 438
FPA GFGAKLPP+GR+SH+FPLN N E+P+C GI+G+LE+Y +SLRTVQLYGPT FAPV+
Sbjct: 350 FPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVI 409
Query: 439 THVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAM 498
VAR AA + DGSQY VLLIITDGVISDM QTKEAIV+A+ LPMSIIIVGVG A F+AM
Sbjct: 410 NQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAM 469
Query: 499 VELDGDDVRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
ELDGDDVR+SSRG+ AERDIVQFVPFRDYVDR+GN VLSMARLA+DVLAEIP+QL+SYM
Sbjct: 470 EELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYM 529
Query: 559 KAQGIRPRPPPAAPTHSPSQSPARTPP 585
+ + I+PRPPP A +PS PA P
Sbjct: 530 RTRDIQPRPPPPA---NPSPIPAPEQP 553
>gi|4503015 copine III [Homo sapiens]
Length = 537
Score = 538 bits (1385), Expect = e-153
Identities = 288/553 (52%), Positives = 370/553 (66%), Gaps = 33/553 (5%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
TKV + VSC NLLDKD+ SKSDPLCV++ +QW E RTE I N LNP F + FI+
Sbjct: 7 TKVALNVSCANLLDKDIGSKSDPLCVLFLN-TSGQQWYEVERTERIKNCLNPQFSKTFII 65
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
DY+FE Q L+F +YD+D+K+ +LS DFLG+ CTLG+IV S +L +PL +
Sbjct: 66 DYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSS--KKLTRPLVM------ 117
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+TG+P GK G+I +SAEE+ + R V + A KLD KD FGKSDP+L
Sbjct: 118 -KTGRPA---------GK--GSITISAEEIKDNR-VVLFEMEARKLDNKDLFGKSDPYLE 164
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F++ DG + + H+TEV+KN LNPVW+ F I + +LC GD D+TIKVE YD+D DGSHD
Sbjct: 165 FHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHD 224
Query: 263 FIGEFTTSYRELARGQSQFNI-YEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYI 321
IG F T+ +L + +E +N KK+ KKK Y NSG +++ + ECTFLDYI
Sbjct: 225 LIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYI 284
Query: 322 KGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPA 381
GG Q+NFTV +DFT SNG+P SLHY+SP +N Y AL +VG +IQ YD+DKMFPA
Sbjct: 285 MGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPA 344
Query: 382 LGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHV 441
GFGA++PP +VSHEFP+N N NP C GI GI+EAY L ++LYGPTNF+P++ HV
Sbjct: 345 FGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHV 404
Query: 442 ARNAAAV---QDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAM 498
AR AAA Q SQY VLLIITDGVI+D+ +T++AIVNA++LPMSIIIVGVG A+F AM
Sbjct: 405 ARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAM 464
Query: 499 VELDGDDVRI-SSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSY 557
LDGD + S G++A RDIVQFVPFR + + LA+ VLAEIP Q+V Y
Sbjct: 465 EFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQN------APKEALAQCVLAEIPQQVVGY 518
Query: 558 MKAQGIRPRPPPA 570
+ P PA
Sbjct: 519 FNTYKLLPPKNPA 531
>gi|30181236 copine II [Homo sapiens]
Length = 548
Score = 529 bits (1362), Expect = e-150
Identities = 283/547 (51%), Positives = 373/547 (68%), Gaps = 34/547 (6%)
Query: 24 KVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVD 83
KVE++VS +NLLD+D+ SKSDP CV++T+ N +W E+ RTE N LNP F +KF++D
Sbjct: 25 KVELSVSGQNLLDRDVTSKSDPFCVLFTEN--NGRWIEYDRTETAINNLNPAFSKKFVLD 82
Query: 84 YFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNS 143
Y FEE Q L+F L+D D S L +HDFLGQ C+LG IV S ++ +PL + LN
Sbjct: 83 YHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSS--KKITRPLLL----LND 136
Query: 144 RTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVF 203
+ PA GK G I ++A+ELS+ R V T+ +LDKKD FGKSDPFL F
Sbjct: 137 K-----PA-------GK--GLITIAAQELSDNR-VITLSLAGRRLDKKDLFGKSDPFLEF 181
Query: 204 YRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDF 263
Y+ +DG + + H+TEV+K TL+PVW+ F++P+ +LC+GD ++ I+V YD+D DG HDF
Sbjct: 182 YKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYDYDNDGGHDF 241
Query: 264 IGEFTTSYRELARGQSQFNI-YEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IGEF TS ++ + + +E +NPKK+ KKK Y NSG + L S + + +FLDYI
Sbjct: 242 IGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYIL 301
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG Q+ FTV IDFTASNGNP +SLHY++P N Y A+ AVG+IIQ YDSDKMFPAL
Sbjct: 302 GGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPAL 361
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA+LPPD +VSHEF +N N NP C G+DGI +AY L ++ YGPTNF+P+V HVA
Sbjct: 362 GFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVA 421
Query: 443 RNAAAV---QDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA + +QY +LLIITDGVISDM +T+ A+V A+KLPMSIIIVGVG A+F AM
Sbjct: 422 RFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAME 481
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
LDGD + S G+ A RDIVQFVPFR++ + + LA+ VLAE+P Q+V Y
Sbjct: 482 FLDGDSRMLRSHTGEEAARDIVQFVPFREFRN------AAKETLAKAVLAELPQQVVQYF 535
Query: 559 KAQGIRP 565
K + + P
Sbjct: 536 KHKNLPP 542
>gi|18677733 copine IV [Homo sapiens]
Length = 557
Score = 515 bits (1326), Expect = e-146
Identities = 274/549 (49%), Positives = 361/549 (65%), Gaps = 34/549 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
TKVE+ V+C+ + D+D SK DP ++ Q + QW E RTEVI +NP + + F V
Sbjct: 24 TKVELRVACKGISDRDALSKPDPCVILKMQS--HGQWFEVDRTEVIRTCINPVYSKLFTV 81
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
D++FEE Q LRF+++D+ S L + DFLG CTLG+IV +L K L
Sbjct: 82 DFYFEEVQRLRFEVHDISSNHNGLKEADFLGGMECTLGQIVSQ--RKLSKSL-------- 131
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ +G GK T+I AEELS D + F A KLD KDFF KSDPFL
Sbjct: 132 ---------LKHGNTAGKSSITVI--AEELSGNDDYVELAFNARKLDDKDFFSKSDPFLE 180
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
+R N+D T + H+TEV+ N L+P W++F + V +LC+GD DR +K V+DWD +G HD
Sbjct: 181 IFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNGKHD 240
Query: 263 FIGEFTTSYRELARGQSQFNI-YEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYI 321
FIGEFT++++E+ + +E +NPK K KKK Y NSGTV L + +FLDYI
Sbjct: 241 FIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFLDYI 300
Query: 322 KGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPA 381
GG QI FTVAIDFTASNG+P S SLHY+ PYQ N Y AL AVGEI Q YDSDKMFPA
Sbjct: 301 MGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKMFPA 360
Query: 382 LGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHV 441
GFGA++PP+ VSH+F +N N++NP C GI G++EAY L +QLYGPTN AP++ V
Sbjct: 361 FGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPIIQKV 420
Query: 442 ARNAAA---VQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAM 498
A++A+ ++ SQY +LLI+TDGVI+DMA T+EAIV+A+ LPMS+IIVGVG A+F M
Sbjct: 421 AKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADFSDM 480
Query: 499 VELDGDD-VRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSY 557
LDGDD + S +G+ RDIVQFVPFR++ H S A LA+ VLAE+P+Q+V Y
Sbjct: 481 QMLDGDDGILRSPKGEPVLRDIVQFVPFRNF-----KHA-SPAALAKSVLAEVPNQVVDY 534
Query: 558 MKAQGIRPR 566
+GI+P+
Sbjct: 535 YNGKGIKPK 543
>gi|23397708 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397706 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397704 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397702 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397700 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397698 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|23397696 copine I isoform a [Homo sapiens]
Length = 537
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 6 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 64
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 65 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 116
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 117 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 163
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 164 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 222
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 223 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 279
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 280 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 339
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 340 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 399
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 400 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 459
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 460 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 513
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 514 RAQGWAPLKPLPPSAKDPAQAP 535
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 1 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 57
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 58 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 110
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 111 TLPLMLKPGKPAGRGTITV 129
>gi|197333761 copine I isoform b [Homo sapiens]
Length = 542
Score = 510 bits (1314), Expect = e-144
Identities = 276/562 (49%), Positives = 373/562 (66%), Gaps = 36/562 (6%)
Query: 23 TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIV 82
T V++++SC +L+DKD+ SKSDPLCV+ Q + W E GRTE + N +P+F + +
Sbjct: 11 TLVQLSISCDHLIDKDIGSKSDPLCVLL-QDVGGGSWAELGRTERVRNCSSPEFSKTLQL 69
Query: 83 DYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLN 142
+Y FE Q LRF +YD+D+K+P+L DFLG A C+LG+IV S L PL +
Sbjct: 70 EYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSS--QVLTLPLML------ 121
Query: 143 SRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLV 202
+ GKP GTI +SA+EL + R V TM+ A LDKKDF GKSDPFL
Sbjct: 122 -KPGKPAGR-----------GTITVSAQELKDNR-VVTMEVEARNLDKKDFLGKSDPFLE 168
Query: 203 FYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
F+R DG + + +++EV+KN LNP W+ FS+PV+ C G+ I+V+ D+D DGSHD
Sbjct: 169 FFRQG-DGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSDGSHD 227
Query: 263 FIGEFTTSYRELARGQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIK 322
IG F TS +L ++F E ++P+K+ KKK Y NSGT+ + VE+E +FLDY+
Sbjct: 228 LIGTFHTSLAQLQAVPAEF---ECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLDYVM 284
Query: 323 GGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPAL 382
GG QINFTV +DFT SNG+PS SLHY+SP +N Y +AL +VG ++Q YDSDK+FPA
Sbjct: 285 GGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDKLFPAF 344
Query: 383 GFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVA 442
GFGA++PPD +VSHEF LN N NP C GI GI++AY ++L V+LYGPTNFAP++ HVA
Sbjct: 345 GFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFAPIINHVA 404
Query: 443 RNAA-AVQDG--SQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMV 499
R AA A G SQY +LL++TDG ++D+ T+EA+V A+ LPMS+IIVGVG A+F+AM
Sbjct: 405 RFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVGGADFEAME 464
Query: 500 ELDGDDVRISSR-GKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIPDQLVSYM 558
+LD D + +R G+ A RDIVQFVP+R + + LA+ VLAE+P QLVSY
Sbjct: 465 QLDADGGPLHTRSGQAAARDIVQFVPYRRFQN------APREALAQTVLAEVPTQLVSYF 518
Query: 559 KAQGIRPRPPPAAPTHSPSQSP 580
+AQG P P P+Q+P
Sbjct: 519 RAQGWAPLKPLPPSAKDPAQAP 540
Score = 32.3 bits (72), Expect = 1.3
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 14/139 (10%)
Query: 172 LSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT 231
+++C + + + L KD KSDP V + G++ +TE ++N +P
Sbjct: 6 MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAELGRTERVRNCSSP---E 62
Query: 232 FSIPVRALCNGDYDRTIKVEVYDWDRD----GSHDFIGEFTTSYRELARGQSQFNIYEVV 287
FS ++ + + ++ +YD D DF+G S ++ Q V+
Sbjct: 63 FSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLGQIVSSQ-------VL 115
Query: 288 NPKKKMKKKKYVNSGTVTL 306
+K K GT+T+
Sbjct: 116 TLPLMLKPGKPAGRGTITV 134
>gi|25141328 copine 7 isoform a [Homo sapiens]
Length = 558
Score = 489 bits (1258), Expect = e-138
Identities = 278/579 (48%), Positives = 364/579 (62%), Gaps = 46/579 (7%)
Query: 18 GSIPA---TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNP 74
G +PA +KVE+ +SCR+LLD+D +KSDP + Q QW + GRTEV+ ++L+P
Sbjct: 14 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHP 71
Query: 75 DFVRKFIVDYFFEEKQNLRFDLYDVDSKSP-DLSKHDFLGQAFCTLGEIVGSPGSRLEKP 133
F + F VDY+FEE Q LRF++YD S + DFLG CTLG+IV ++ +P
Sbjct: 72 VFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQ--KKVTRP 129
Query: 134 LTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDF 193
L + GK TI + AE++S + F A KLD KD
Sbjct: 130 LLL---KFGRNAGK---------------STITVIAEDISGNNGYVELSFRARKLDDKDL 171
Query: 194 FGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVY 253
F KSDPFL YR N+D + ++TEV+KN LNPVW+ F + + +LC+ + R +K V+
Sbjct: 172 FSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVW 231
Query: 254 DWDRDGSHDFIGEFTTSYRELAR----GQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSF 309
D+D G HDFIGEF+T++ E+ + GQ+Q ++ VNPK K K++ Y NSG V L
Sbjct: 232 DYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADL 288
Query: 310 AVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEI 369
+FLDYI GG QI+FTVAIDFTASNG+P S SLHY++PYQ N Y AL +VGEI
Sbjct: 289 KFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEI 348
Query: 370 IQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLY 429
Q YDSDK F ALGFGA++PP VSH+F +N N E+ C GI G++EAY L VQLY
Sbjct: 349 CQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLY 408
Query: 430 GPTNFAPVVTHVARNAAAVQD---GSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSII 486
GPTN AP+++ VAR AAA + SQY +LLI+TDGV++DMA T+EAIV A++LPMSII
Sbjct: 409 GPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSII 468
Query: 487 IVGVGQAEFDAMVELDGDD-VRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARD 545
IVGVG A+F M LDGDD V S RG+ A RDIVQFVPFR+ + S A LA+
Sbjct: 469 IVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKC 522
Query: 546 VLAEIPDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTP 584
VLAE+P Q+V Y +G+ PP + + SP TP
Sbjct: 523 VLAEVPKQVVEYYSHRGL---PPRSLGVPAGEASPGCTP 558
>gi|5174421 copine 6 [Homo sapiens]
Length = 557
Score = 482 bits (1241), Expect = e-136
Identities = 272/570 (47%), Positives = 357/570 (62%), Gaps = 36/570 (6%)
Query: 19 SIPATKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVR 78
++ A++VE+ VSC LLD+D +K P CV+ ++QW E RTEV+ + +P F R
Sbjct: 16 TLGASRVELRVSCHGLLDRDTLTKPHP-CVLLKL-YSDEQWVEVERTEVLRSCSSPVFSR 73
Query: 79 KFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGA 138
++YFFEEKQ L+F ++D + + FLG CTLG+IV +++ KPL +
Sbjct: 74 VLALEYFFEEKQPLQFHVFDAEDGATSPRNDTFLGSTECTLGQIVSQ--TKVTKPLLL-- 129
Query: 139 FSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSD 198
NG GK TI + AEE+S D + F A KLD KD F KSD
Sbjct: 130 --------------KNGKTAGKS--TITIVAEEVSGTNDYVQLTFRAYKLDNKDLFSKSD 173
Query: 199 PFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD 258
PF+ Y++NED + + +TEV+KN LNP W+ F + + +LC+ D R +K VYD+D
Sbjct: 174 PFMEIYKTNEDQSDQLVWRTEVVKNNLNPSWEPFRLSLHSLCSCDVHRPLKFLVYDYDSS 233
Query: 259 GSHDFIGEFTTSYRELARGQS---QFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESEC 315
G HDFIGEFT++++E+ G + Q ++ +NPK + KKK Y +SGTV L VE
Sbjct: 234 GKHDFIGEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKNYKSSGTVVLAQCTVEKVH 293
Query: 316 TFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDS 375
TFLDYI GG QI+FTVAIDFTASNG+P S SLH +SP Q N Y AL AVG I Q YDS
Sbjct: 294 TFLDYIMGGCQISFTVAIDFTASNGDPRSSQSLHCLSPRQPNHYLQALRAVGGICQDYDS 353
Query: 376 DKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFA 435
DK FPA GFGA++PP+ VSH+F +N + ENP C I G++ +Y R L +QLYGPTN A
Sbjct: 354 DKRFPAFGFGARIPPNFEVSHDFAINFDPENPECEEISGVIASYRRCLPQIQLYGPTNVA 413
Query: 436 PVVTHVARNAAAVQDGSQ---YSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQ 492
P++ VA A Q Q YSVLL++TDGV+SDMA+T+ AIV A++LPMSIIIVGVG
Sbjct: 414 PIINRVAEPAQREQSTGQATKYSVLLVLTDGVVSDMAETRTAIVRASRLPMSIIIVGVGN 473
Query: 493 AEFDAMVELDGDDVRI-SSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEIP 551
A+F M LDGDD + RG A RDIVQFVPFRD+ D + + LA+ VLAE+P
Sbjct: 474 ADFSDMRLLDGDDGPLRCPRGVPAARDIVQFVPFRDFKD------AAPSALAKCVLAEVP 527
Query: 552 DQLVSYMKAQGIRP-RPPPAAPTHSPSQSP 580
Q+V Y +QGI P P P +PS SP
Sbjct: 528 RQVVEYYASQGISPGAPRPCTLATTPSPSP 557
>gi|7656993 copine 7 isoform b [Homo sapiens]
Length = 633
Score = 474 bits (1220), Expect = e-133
Identities = 283/634 (44%), Positives = 371/634 (58%), Gaps = 81/634 (12%)
Query: 18 GSIPA---TKVEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNP 74
G +PA +KVE+ +SCR+LLD+D +KSDP + Q QW + GRTEV+ ++L+P
Sbjct: 14 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQG--QWVQVGRTEVVRSSLHP 71
Query: 75 DFVRKFIVDYFFEEKQNLRFDLYDVDSKSP-DLSKHDFLGQAFCTLGE------------ 121
F + F VDY+FEE Q LRF++YD S + DFLG CTLG+
Sbjct: 72 VFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMR 131
Query: 122 ----IVGSPGSRLEKPLTIGAFSLNSRTGKP---------MPAVSNGGVPGKKC------ 162
++G G + L S +RTG +P + G V C
Sbjct: 132 VSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQ 191
Query: 163 ------------------------GTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSD 198
TI + AE++S + F A KLD KD F KSD
Sbjct: 192 GWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSD 251
Query: 199 PFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD 258
PFL YR N+D + ++TEV+KN LNPVW+ F + + +LC+ + R +K V+D+D
Sbjct: 252 PFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSR 311
Query: 259 GSHDFIGEFTTSYRELAR----GQSQFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESE 314
G HDFIGEF+T++ E+ + GQ+Q ++ VNPK K K++ Y NSG V L
Sbjct: 312 GKHDFIGEFSTTFEEMQKAFEEGQAQ---WDCVNPKYKQKRRSYKNSGVVVLADLKFHRV 368
Query: 315 CTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYD 374
+FLDYI GG QI+FTVAIDFTASNG+P S SLHY++PYQ N Y AL +VGEI Q YD
Sbjct: 369 YSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYD 428
Query: 375 SDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNF 434
SDK F ALGFGA++PP VSH+F +N N E+ C GI G++EAY L VQLYGPTN
Sbjct: 429 SDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNV 488
Query: 435 APVVTHVARNAAAVQD---GSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVG 491
AP+++ VAR AAA + SQY +LLI+TDGV++DMA T+EAIV A++LPMSIIIVGVG
Sbjct: 489 APIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVG 548
Query: 492 QAEFDAMVELDGDD-VRISSRGKLAERDIVQFVPFRDYVDRTGNHVLSMARLARDVLAEI 550
A+F M LDGDD V S RG+ A RDIVQFVPFR+ + S A LA+ VLAE+
Sbjct: 549 NADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN------ASPAALAKCVLAEV 602
Query: 551 PDQLVSYMKAQGIRPRPPPAAPTHSPSQSPARTP 584
P Q+V Y +G+ PP + + SP TP
Sbjct: 603 PKQVVEYYSHRGL---PPRSLGVPAGEASPGCTP 633
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 55.8 bits (133), Expect = 1e-07
Identities = 70/260 (26%), Positives = 101/260 (38%), Gaps = 36/260 (13%)
Query: 29 VSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEE 88
+ +L KD SDP MY K+++ T V TLNP F F +++
Sbjct: 253 IKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQ----TRVHRKTLNPLFDETFQFPVAYDQ 308
Query: 89 KQN--LRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTG 146
N L F +YD D S+HD +G+ L+ + S +
Sbjct: 309 LSNRKLHFSVYDFDR----FSRHDMIGEVI-------------LDNLFEVSDLSREATVW 351
Query: 147 KPMPAVSNGGVPGKKCGTIILSAEELSNC-RDVATMQFCANKLDKKDFFGKSDPFLVFYR 205
K + + + G I+ S L R T+ C N L D G SDP++
Sbjct: 352 KDIHCATTESID---LGEIMFSLCYLPTAGRMTLTVIKCRN-LKAMDITGSSDPYVKVSL 407
Query: 206 SNEDGTFTICHKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHD 262
E G KT KNTLNPV+ F IP N D ++ + V D+DR G ++
Sbjct: 408 MCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPE---NVD-QVSLSIAVMDYDRVGHNE 462
Query: 263 FIGEFTTSYRELARGQSQFN 282
IG T G+ +N
Sbjct: 463 VIGVCRTGLDAEGLGRDHWN 482
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/238 (28%), Positives = 97/238 (40%), Gaps = 34/238 (14%)
Query: 33 NLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFI--VDYFFEEKQ 90
NL KD SDP +Y + +++ + +T+V TLNP F F+ V Y E +
Sbjct: 246 NLPAKDFSGTSDPYVKIYL--LPDRKTKH--QTKVHRKTLNPVFDEVFLFPVPYNDLEAR 301
Query: 91 NLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMP 150
L F +YD D S+HD +GQ ++ L + F K +
Sbjct: 302 KLHFSVYDFDR----FSRHDLIGQVV-------------VDHFLDLADFPRECILWKDIE 344
Query: 151 AVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDG 210
V+N V G ++ S L + A L D G SDP+ V DG
Sbjct: 345 YVTNDNVD---LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPY-VKVSLMCDG 400
Query: 211 TFTICHKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIG 265
KT +NTLNPV+ F +P N D + + V D+DR G ++ IG
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPE---NIDQIH-LSIAVMDYDRVGHNEIIG 454
Score = 49.3 bits (116), Expect = 1e-05
Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243
A L KDF G SDP++ Y + T H+T+V + TLNPV+ + F PV N
Sbjct: 244 AVNLPAKDFSGTSDPYVKIYLLPDRKTK---HQTKVHRKTLNPVFDEVFLFPVPY--NDL 298
Query: 244 YDRTIKVEVYDWDRDGSHDFIGEFTTSY 271
R + VYD+DR HD IG+ +
Sbjct: 299 EARKLHFSVYDFDRFSRHDLIGQVVVDH 326
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 53.9 bits (128), Expect = 4e-07
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 5/93 (5%)
Query: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243
A L D G SDP++ + T KT +K TLNPVW +TF ++ GD
Sbjct: 180 ARNLIPMDPNGLSDPYVKLKLIPDPRNLTK-QKTRTVKATLNPVWNETFVFNLKP---GD 235
Query: 244 YDRTIKVEVYDWDRDGSHDFIGEFTTSYRELAR 276
+R + VEV+DWDR +DF+G + EL +
Sbjct: 236 VERRLSVEVWDWDRTSRNDFMGAMSFGVSELLK 268
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/239 (24%), Positives = 95/239 (39%), Gaps = 35/239 (14%)
Query: 38 DMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEK--QNLRFD 95
DM SDP ++ + K++ T+V TLNP F +F + E + L
Sbjct: 173 DMGGTSDPYVKVFLLPDKKKKFE----TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMA 228
Query: 96 LYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNG 155
+YD D SKHD +G+ + P+ F + + + +
Sbjct: 229 VYDFDR----FSKHDIIGE---------------FKVPMNTVDFGHVTEEWRDLQSAEKE 269
Query: 156 GVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTIC 215
+K G I S + + + A L K D G SDP++ + ++G
Sbjct: 270 --EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKK 326
Query: 216 HKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSY 271
KT + KNTLNP + +F +P + + V V D+D+ G +D IG+ Y
Sbjct: 327 KKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ----VVVTVLDYDKIGKNDAIGKVFVGY 381
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 12/87 (13%)
Query: 185 ANKLDKKDFFGKSDPFL-VFYRSNEDGTFTICHKTEVMKNTLNPVWQ---TFSIPVRALC 240
A +L D G SDP++ VF ++ F +T+V + TLNPV+ TF +P L
Sbjct: 166 AAELPALDMGGTSDPYVKVFLLPDKKKKF----ETKVHRKTLNPVFNEQFTFKVPYSELG 221
Query: 241 NGDYDRTIKVEVYDWDRDGSHDFIGEF 267
+T+ + VYD+DR HD IGEF
Sbjct: 222 G----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 27 ITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFF 86
+ + +NL D+ SDP ++ M+N + + +T + NTLNP + F + F
Sbjct: 293 VILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF 350
Query: 87 EEKQNLRFDLYDVDSKSPDLSKHDFLGQAF 116
E+ Q ++ + +D + K+D +G+ F
Sbjct: 351 EQIQKVQVVVTVLDYDK--IGKNDAIGKVF 378
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/239 (24%), Positives = 95/239 (39%), Gaps = 35/239 (14%)
Query: 38 DMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEK--QNLRFD 95
DM SDP ++ + K++ T+V TLNP F +F + E + L
Sbjct: 173 DMGGTSDPYVKVFLLPDKKKKFE----TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMA 228
Query: 96 LYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNG 155
+YD D SKHD +G+ + P+ F + + + +
Sbjct: 229 VYDFDR----FSKHDIIGE---------------FKVPMNTVDFGHVTEEWRDLQSAEKE 269
Query: 156 GVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTIC 215
+K G I S + + + A L K D G SDP++ + ++G
Sbjct: 270 --EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKK 326
Query: 216 HKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSY 271
KT + KNTLNP + +F +P + + V V D+D+ G +D IG+ Y
Sbjct: 327 KKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ----VVVTVLDYDKIGKNDAIGKVFVGY 381
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 12/87 (13%)
Query: 185 ANKLDKKDFFGKSDPFL-VFYRSNEDGTFTICHKTEVMKNTLNPVWQ---TFSIPVRALC 240
A +L D G SDP++ VF ++ F +T+V + TLNPV+ TF +P L
Sbjct: 166 AAELPALDMGGTSDPYVKVFLLPDKKKKF----ETKVHRKTLNPVFNEQFTFKVPYSELG 221
Query: 241 NGDYDRTIKVEVYDWDRDGSHDFIGEF 267
+T+ + VYD+DR HD IGEF
Sbjct: 222 G----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 27 ITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFF 86
+ + +NL D+ SDP ++ M+N + + +T + NTLNP + F + F
Sbjct: 293 VILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF 350
Query: 87 EEKQNLRFDLYDVDSKSPDLSKHDFLGQAF 116
E+ Q ++ + +D + K+D +G+ F
Sbjct: 351 EQIQKVQVVVTVLDYDK--IGKNDAIGKVF 378
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 51.6 bits (122), Expect = 2e-06
Identities = 58/239 (24%), Positives = 95/239 (39%), Gaps = 35/239 (14%)
Query: 38 DMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEEK--QNLRFD 95
DM SDP ++ + K++ T+V TLNP F +F + E + L
Sbjct: 173 DMGGTSDPYVKVFLLPDKKKKFE----TKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMA 228
Query: 96 LYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNG 155
+YD D SKHD +G+ + P+ F + + + +
Sbjct: 229 VYDFDR----FSKHDIIGE---------------FKVPMNTVDFGHVTEEWRDLQSAEKE 269
Query: 156 GVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTIC 215
+K G I S + + + A L K D G SDP++ + ++G
Sbjct: 270 --EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLM-QNGKRLKK 326
Query: 216 HKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSY 271
KT + KNTLNP + +F +P + + V V D+D+ G +D IG+ Y
Sbjct: 327 KKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ----VVVTVLDYDKIGKNDAIGKVFVGY 381
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 12/87 (13%)
Query: 185 ANKLDKKDFFGKSDPFL-VFYRSNEDGTFTICHKTEVMKNTLNPVWQ---TFSIPVRALC 240
A +L D G SDP++ VF ++ F +T+V + TLNPV+ TF +P L
Sbjct: 166 AAELPALDMGGTSDPYVKVFLLPDKKKKF----ETKVHRKTLNPVFNEQFTFKVPYSELG 221
Query: 241 NGDYDRTIKVEVYDWDRDGSHDFIGEF 267
+T+ + VYD+DR HD IGEF
Sbjct: 222 G----KTLVMAVYDFDRFSKHDIIGEF 244
Score = 33.5 bits (75), Expect = 0.57
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 27 ITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFF 86
+ + +NL D+ SDP ++ M+N + + +T + NTLNP + F + F
Sbjct: 293 VILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF 350
Query: 87 EEKQNLRFDLYDVDSKSPDLSKHDFLGQAF 116
E+ Q ++ + +D + K+D +G+ F
Sbjct: 351 EQIQKVQVVVTVLDYDK--IGKNDAIGKVF 378
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 51.2 bits (121), Expect = 3e-06
Identities = 38/118 (32%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 160 KKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTE 219
+K G I L AE V A L D G SDP+ V + D KT+
Sbjct: 157 EKRGRIYLKAEVADEKLHVTVRD--AKNLIPMDPNGLSDPY-VKLKLIPDPKNESKQKTK 213
Query: 220 VMKNTLNPVW-QTFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELAR 276
+++TLNP W ++F+ ++ D DR + VE++DWDR +DF+G + EL +
Sbjct: 214 TIRSTLNPQWNESFTFKLKP---SDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMK 268
>gi|50582996 multiple C2 domains, transmembrane 1 isoform S [Homo
sapiens]
Length = 778
Score = 50.8 bits (120), Expect = 3e-06
Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 33/233 (14%)
Query: 64 RTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIV 123
+++++ TLNP + +F + E + +D D+ D DF+G+ L +
Sbjct: 284 KSKIMPKTLNPQWREQFDFHLYEERGGVIDITAWDKDAGKRD----DFIGRCQVDLSALS 339
Query: 124 GSPGSRLEKPLTIGA------FSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEE----LS 173
+LE L G +L + + +S + +K IL
Sbjct: 340 REQTHKLELQLEEGEGHLVLLVTLTASATVSISDLSVNSLEDQKEREEILKRYSPLRIFH 399
Query: 174 NCRDVATMQ---FCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQ 230
N +DV +Q A L D GKSDPF V +N+ T + LNP W
Sbjct: 400 NLKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLL------THTVYKNLNPEWN 453
Query: 231 ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQ 280
TF+I D ++V VYD DRD S DF+G+ + G+ +
Sbjct: 454 KVFTFNIK-------DIHSVLEVTVYDEDRDRSADFLGKVAIPLLSIQNGEQK 499
Score = 34.3 bits (77), Expect = 0.33
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 15/95 (15%)
Query: 188 LDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGDYDR 246
L D G SDP++ F ++ +K+++M TLNP W + F + +R
Sbjct: 261 LKAMDSNGLSDPYVKFRLGHQK------YKSKIMPKTLNPQWREQFDFHLYE------ER 308
Query: 247 TIKVEVYDWDRDGS--HDFIGEFTTSYRELARGQS 279
+++ WD+D DFIG L+R Q+
Sbjct: 309 GGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQT 343
Score = 30.0 bits (66), Expect = 6.3
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 11/79 (13%)
Query: 188 LDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDR- 246
L +D G SDP++ F ++ +++++ LNPVW+ +A D+ R
Sbjct: 52 LAARDRGGTSDPYVKFKIGGKE-----VFRSKIIHKNLNPVWEE-----KACILVDHLRE 101
Query: 247 TIKVEVYDWDRDGSHDFIG 265
+ ++V+D+D DF+G
Sbjct: 102 PLYIKVFDYDFGLQDDFMG 120
>gi|205361109 multiple C2 domains, transmembrane 1 isoform L [Homo
sapiens]
Length = 999
Score = 50.8 bits (120), Expect = 3e-06
Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 33/233 (14%)
Query: 64 RTEVIDNTLNPDFVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIV 123
+++++ TLNP + +F + E + +D D+ D DF+G+ L +
Sbjct: 505 KSKIMPKTLNPQWREQFDFHLYEERGGVIDITAWDKDAGKRD----DFIGRCQVDLSALS 560
Query: 124 GSPGSRLEKPLTIGA------FSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEE----LS 173
+LE L G +L + + +S + +K IL
Sbjct: 561 REQTHKLELQLEEGEGHLVLLVTLTASATVSISDLSVNSLEDQKEREEILKRYSPLRIFH 620
Query: 174 NCRDVATMQ---FCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQ 230
N +DV +Q A L D GKSDPF V +N+ T + LNP W
Sbjct: 621 NLKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLL------THTVYKNLNPEWN 674
Query: 231 ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQ 280
TF+I D ++V VYD DRD S DF+G+ + G+ +
Sbjct: 675 KVFTFNIK-------DIHSVLEVTVYDEDRDRSADFLGKVAIPLLSIQNGEQK 720
Score = 34.3 bits (77), Expect = 0.33
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 15/95 (15%)
Query: 188 LDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGDYDR 246
L D G SDP++ F ++ +K+++M TLNP W + F + +R
Sbjct: 482 LKAMDSNGLSDPYVKFRLGHQK------YKSKIMPKTLNPQWREQFDFHLYE------ER 529
Query: 247 TIKVEVYDWDRDGS--HDFIGEFTTSYRELARGQS 279
+++ WD+D DFIG L+R Q+
Sbjct: 530 GGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQT 564
Score = 30.0 bits (66), Expect = 6.3
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 11/79 (13%)
Query: 188 LDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDR- 246
L +D G SDP++ F ++ +++++ LNPVW+ +A D+ R
Sbjct: 273 LAARDRGGTSDPYVKFKIGGKE-----VFRSKIIHKNLNPVWEE-----KACILVDHLRE 322
Query: 247 TIKVEVYDWDRDGSHDFIG 265
+ ++V+D+D DF+G
Sbjct: 323 PLYIKVFDYDFGLQDDFMG 341
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 48.9 bits (115), Expect = 1e-05
Identities = 40/139 (28%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 131 EKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDK 190
E+P +IG K + K CG I S + A L
Sbjct: 114 EQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPA 173
Query: 191 KDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT---FSIPVRALCNGDYDRT 247
KDF G SDP++ Y + +T V + TLNP + F +P L DR
Sbjct: 174 KDFCGSSDPYVKIYLLPDRKCKL---QTRVHRKTLNPTFDENFHFPVPYEELA----DRK 226
Query: 248 IKVEVYDWDRDGSHDFIGE 266
+ + V+D+DR HD IGE
Sbjct: 227 LHLSVFDFDRFSRHDMIGE 245
Score = 45.4 bits (106), Expect = 1e-04
Identities = 63/251 (25%), Positives = 95/251 (37%), Gaps = 34/251 (13%)
Query: 37 KDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEE--KQNLRF 94
KD SDP +Y + +++ + +T V TLNP F F +EE + L
Sbjct: 174 KDFCGSSDPYVKIYL--LPDRKCKL--QTRVHRKTLNPTFDENFHFPVPYEELADRKLHL 229
Query: 95 DLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSN 154
++D D S+HD +G+ L+ S + K + ++
Sbjct: 230 SVFDFDR----FSRHDMIGEVI-------------LDNLFEASDLSRETSIWKDIQYATS 272
Query: 155 GGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTI 214
V G I+ S L + L D G SDP+ V DG
Sbjct: 273 ESVD---LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPY-VKVSLLCDGRRLK 328
Query: 215 CHKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSY 271
KT + KNTLNPV+ F IP N D ++ + V D+DR G ++ IG
Sbjct: 329 KKKTTIKKNTLNPVYNEAIIFDIPPE---NMD-QVSLLISVMDYDRVGHNEIIGVCRVGI 384
Query: 272 RELARGQSQFN 282
G+ +N
Sbjct: 385 TAEGLGRDHWN 395
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243
A L D G SDP+ V + D KT+ +K +LNP W +TF ++ D
Sbjct: 180 AKNLVPMDPNGLSDPY-VKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLK---ESD 235
Query: 244 YDRTIKVEVYDWDRDGSHDFIGEFTTSYRELAR 276
DR + VE++DWD +DF+G + EL +
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQK 268
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 47.0 bits (110), Expect = 5e-05
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 185 ANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVW-QTFSIPVRALCNGD 243
A L D G SDP+ V + D KT+ +K +LNP W +TF ++ D
Sbjct: 180 AKNLVPMDPNGLSDPY-VKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLK---ESD 235
Query: 244 YDRTIKVEVYDWDRDGSHDFIGEFTTSYRELAR 276
DR + VE++DWD +DF+G + EL +
Sbjct: 236 KDRRLSVEIWDWDLTSRNDFMGSLSFGISELQK 268
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 47.0 bits (110), Expect = 5e-05
Identities = 45/151 (29%), Positives = 60/151 (39%), Gaps = 18/151 (11%)
Query: 126 PGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGK-------KCGTIILSAEELSNCRDV 178
PG EK IG G +GG PG CG I + L +
Sbjct: 258 PGGE-EKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRISFALRYLYGSDQL 316
Query: 179 ATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQT---FSIP 235
A L KD G SDP++ Y + +T+V + TLNPV+ FS+P
Sbjct: 317 VVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK---FQTKVHRKTLNPVFNETFQFSVP 373
Query: 236 VRALCNGDYDRTIKVEVYDWDRDGSHDFIGE 266
+ L R + VYD+DR HD IG+
Sbjct: 374 LAELAQ----RKLHFSVYDFDRFSRHDLIGQ 400
Score = 46.2 bits (108), Expect = 8e-05
Identities = 62/235 (26%), Positives = 90/235 (38%), Gaps = 36/235 (15%)
Query: 37 KDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNTLNPDFVRKFIVDYFFEE--KQNLRF 94
KD SDP +Y K+++ T+V TLNP F F E ++ L F
Sbjct: 329 KDSNGFSDPYVKIYLLPDRKKKFQ----TKVHRKTLNPVFNETFQFSVPLAELAQRKLHF 384
Query: 95 DLYDVDSKSPDLSKHDFLGQAFC-TLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVS 153
+YD D S+HD +GQ L E+ P R PL +
Sbjct: 385 SVYDFDR----FSRHDLIGQVVLDNLLELAEQPPDR---PL--------------WRDIV 423
Query: 154 NGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFT 213
GG G + S L + A+ L D G SDP++ +E G
Sbjct: 424 EGGSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE-GRRL 482
Query: 214 ICHKTEVMKNTLNPVWQ---TFSIPVRALCNGDYDRTIKVEVYDWDRDGSHDFIG 265
KT + KNTLNP + F + ++ N + + V D+D G ++ IG
Sbjct: 483 KKRKTSIKKNTLNPTYNEALVFDVAPESVENVG----LSIAVVDYDCIGHNEVIG 533
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,215,886
Number of Sequences: 37866
Number of extensions: 1072826
Number of successful extensions: 7346
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 107
Number of HSP's that attempted gapping in prelim test: 6752
Number of HSP's gapped (non-prelim): 490
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.