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Search of human proteins with 25121980
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25121980 dispatched B [Homo sapiens]
(1401 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25121980 dispatched B [Homo sapiens] 2861 0.0
gi|25952134 dispatched A [Homo sapiens] 882 0.0
gi|149274653 patched domain containing 2 [Homo sapiens] 61 9e-09
gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapi... 49 3e-05
gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens] 47 2e-04
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens] 46 2e-04
gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo sapi... 46 3e-04
gi|133922582 zinc finger protein 358 [Homo sapiens] 45 5e-04
gi|91208420 bassoon protein [Homo sapiens] 44 8e-04
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 44 0.001
gi|110832843 TBP-associated factor 4 [Homo sapiens] 44 0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 43 0.002
gi|190341097 rhomboid family 1 [Homo sapiens] 42 0.003
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 42 0.003
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 42 0.003
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 42 0.004
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 42 0.004
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 42 0.004
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 42 0.004
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 42 0.005
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 42 0.005
gi|148612857 sickle tail isoform 3 [Homo sapiens] 42 0.005
gi|148612813 sickle tail isoform 2 [Homo sapiens] 42 0.005
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 42 0.005
gi|19718780 semaphorin 6B precursor [Homo sapiens] 42 0.005
>gi|25121980 dispatched B [Homo sapiens]
Length = 1401
Score = 2861 bits (7416), Expect = 0.0
Identities = 1401/1401 (100%), Positives = 1401/1401 (100%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS
Sbjct: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSH 120
CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSH
Sbjct: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSH 120
Query: 121 GSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVI 180
GSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVI
Sbjct: 121 GSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVI 180
Query: 181 FLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNS 240
FLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNS
Sbjct: 181 FLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNS 240
Query: 241 SSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLW 300
SSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLW
Sbjct: 241 SSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLW 300
Query: 301 NLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQAD 360
NLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQAD
Sbjct: 301 NLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQAD 360
Query: 361 AARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDF 420
AARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDF
Sbjct: 361 AARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDF 420
Query: 421 LSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQEL 480
LSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQEL
Sbjct: 421 LSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQEL 480
Query: 481 LRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYF 540
LRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYF
Sbjct: 481 LRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYF 540
Query: 541 PFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTT 600
PFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTT
Sbjct: 541 PFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTT 600
Query: 601 SAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRW 660
SAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRW
Sbjct: 601 SAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRW 660
Query: 661 EGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYI 720
EGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYI
Sbjct: 661 EGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYI 720
Query: 721 AGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLP 780
AGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLP
Sbjct: 721 AGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLP 780
Query: 781 VDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVET 840
VDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVET
Sbjct: 781 VDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVET 840
Query: 841 LQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSL 900
LQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSL
Sbjct: 841 LQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSL 900
Query: 901 AALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSL 960
AALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSL
Sbjct: 901 AALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSL 960
Query: 961 STEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEAL 1020
STEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEAL
Sbjct: 961 STEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEAL 1020
Query: 1021 FLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPA 1080
FLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPA
Sbjct: 1021 FLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPA 1080
Query: 1081 TVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPG 1140
TVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPG
Sbjct: 1081 TVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPG 1140
Query: 1141 GEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHD 1200
GEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHD
Sbjct: 1141 GEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHD 1200
Query: 1201 GPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPL 1260
GPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPL
Sbjct: 1201 GPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPL 1260
Query: 1261 PASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDL 1320
PASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDL
Sbjct: 1261 PASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDL 1320
Query: 1321 DDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNS 1380
DDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNS
Sbjct: 1321 DDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNS 1380
Query: 1381 QPDLPDVWLRRPSTHTSGYSS 1401
QPDLPDVWLRRPSTHTSGYSS
Sbjct: 1381 QPDLPDVWLRRPSTHTSGYSS 1401
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 882 bits (2279), Expect = 0.0
Identities = 429/993 (43%), Positives = 631/993 (63%), Gaps = 16/993 (1%)
Query: 142 VQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVIFLCTLAGLLGARLPDFSKPLL 201
VQ H+ ++R R F++PKSY+ LIA+WPV VL +C I +C L G+L LPDFS PLL
Sbjct: 162 VQQHIANIRPSRPFKLPKSYAALIADWPVVVLGMCTMFIVVCALVGVLVPELPDFSDPLL 221
Query: 202 GFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNSSS-SHNTLRPAPRGSAQESAV 260
GFEPR T IG +LV W + TG + L P + + SH R + +
Sbjct: 222 GFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHRDDR-----WSDDHYE 276
Query: 261 RPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQDQIRSHT 320
R +R V+ + +++FFC P Y+++VF S+ +LWNL AI SMC ++ +IRSH
Sbjct: 277 REKREVD--WNFHKDSFFCDVPSDRYSRVVFTSSGGETLWNLPAIKSMCNVDNSRIRSHP 334
Query: 321 SFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQADAARTLALLRTCALYYHSGAL 380
FG LCQRT A CCPSW+LGNY+A+L+NRSSC + D + TL LLRTCA +Y +G L
Sbjct: 335 QFGDLCQRTTAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKHYQNGTL 394
Query: 381 VPSC--LGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDFLSPQTTDYQVPSLKYSLL 438
P C + + +C VP KC++ +A+YQ+LH+L+D+DF++P+T DY P+LKYS+L
Sbjct: 395 GPDCWDMAARRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFMTPKTADYATPALKYSML 454
Query: 439 FLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQELLRHFLVQDTVYPLLALVA 498
F PT KG S+M+IYLD W +D T++TG++ G+K L + +L+ DTVYP +A+V
Sbjct: 455 FSPTEKGESMMNIYLDNFEN-WNSSDGVTTITGIEFGIKHSLFQDYLLMDTVYPAIAIVI 513
Query: 499 IFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALLLLSSVCANH 558
+ M +Y +S+F+TLM + ++ SL+V++FLY+V F +FPF+NL AL++L + A+
Sbjct: 514 VLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFHFEFFPFMNLTALIILVGIGADD 573
Query: 559 TLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFYASYLSRLPAVRCL 618
+ D+W +K P ++ V T+ H + V+ TT+AAFYA+Y+S + A+RC
Sbjct: 574 AFVLCDVWNYTKFDKPHAETSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCF 633
Query: 619 ALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRWEGSAPRRLLLALHRRLRG 678
++ GTA+LV+ L + WLPA VLHERYL + + + + ++
Sbjct: 634 GVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFTCFKKPQQQIYDNKSCWTVACQKCHK 693
Query: 679 LRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYIAGVSPRLRLPTLPPPGGQ 738
+ A + SR+ F+++LPC VIKFRY+W+ WF AL GGAYI ++P+++LP+L Q
Sbjct: 694 VLFAISEASRIFFEKVLPCIVIKFRYLWLFWFLALTVGGAYIVCINPKMKLPSLELSEFQ 753
Query: 739 VFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLPVDTGDPLDPRSNSSLVRD 798
VFR SHPFER+DAEY++LF+FE++ GE HMP+ ++WGV P D G+PL+P+S L D
Sbjct: 754 VFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVSPEDNGNPLNPKSKGKLTLD 813
Query: 799 PAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVETLQRWMESPSCARLGPDLC 858
+F+ + P +Q W+L C + RNQ+FF E T CF+ET ++WME+ C C
Sbjct: 814 SSFNIASPASQAWILHFCQKLRNQTFFYQTDEQDFTSCFIETFKQWMENQDCDEPALYPC 873
Query: 859 CGHSDFPWAPQFFLHCLK--MMALEQGPDGTQDL---GLRFDAHGSLAALVLQFQTNFRN 913
C H FP+ + F C+K +M LE+ D G RFD + ++ A+VL+FQ+ +
Sbjct: 874 CSHWSFPYKQEIFELCIKRAIMELERSTGYHLDSKTPGPRFDINDTIRAVVLEFQSTYLF 933
Query: 914 SPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSLSTEPAVVLGLALA 973
+ Y + FY EV W+++EL AP GL GWF S LE Y LQ SLS + +GL++A
Sbjct: 934 TLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVA 993
Query: 974 LAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEALFLSASVGLSVDFT 1033
+AF+ +LL TWN+ +SL+++ ++AGT+ +TVG LVLL W+LN E++ +S +VGLSVDF
Sbjct: 994 VAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFA 1053
Query: 1034 VNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPATVLLYRKLGIILM 1093
V+Y ++Y L P PDR +V FSL + A A+ A F AG +M+P+TVL Y +LG +M
Sbjct: 1054 VHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTFVAGAMMMPSTVLAYTQLGTFMM 1113
Query: 1094 MVKCVSCGFASFFFQSLCCFFGPEKNCGQILWP 1126
++ C+S FA+FFFQ +C GP+ CGQI P
Sbjct: 1114 LIMCISWAFATFFFQCMCRCLGPQGTCGQIPLP 1146
>gi|149274653 patched domain containing 2 [Homo sapiens]
Length = 1392
Score = 60.8 bits (146), Expect = 9e-09
Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 3/141 (2%)
Query: 509 SLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALLLLSSVCANHTLIFFDLWRL 568
S+FL+ + + S LVA FLY V F + Y +N A ++ + + +F + +R
Sbjct: 484 SVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQ 543
Query: 569 SKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFYASYLSRLPAVRCLALFMGTAVLV 628
+ + L L R+ T+ G + LTT+AA+ A+ S++PAV LFM V
Sbjct: 544 A-THLEDPQL--RMIHTVQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVSC 600
Query: 629 HLALTLVWLPASAVLHERYLA 649
LV +PA+ L YLA
Sbjct: 601 CWLAVLVTMPAALGLWSLYLA 621
Score = 50.4 bits (119), Expect = 1e-05
Identities = 54/221 (24%), Positives = 90/221 (40%), Gaps = 29/221 (13%)
Query: 898 GSLAALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPG--LRRGWFTSR----- 950
G + + + F++ QT Y +L +L P G LRRG+ T
Sbjct: 1114 GRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLQQQLQALPEGSVLRRGFQTCEHWKQI 1173
Query: 951 -LELYSLQHSLSTEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVL 1009
+E+ +Q +L L L+L + A + + T ++ L L + ++ G V L V ++
Sbjct: 1174 FMEIVGVQSALCG-----LVLSLLICVAAVAVFTTHILLLLPVLLSILGIVCLVVTIMYW 1228
Query: 1010 LEWQLNTAEALFLSASVGLSVDFTVNYCISY-----HLCPHPDRLSRVAFSLRQTSCATA 1064
W++ EA+ LS VG SVD+ V+ Y +L PH +R R
Sbjct: 1229 SGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPHQAEDARTQRQWRTLEAVRH 1288
Query: 1065 VGAAALFAAGVLMLPATVLLYRKLGIILMMVKCVSCGFASF 1105
VG A + +A ++ L + C+ FA F
Sbjct: 1289 VGVAIVSSALTTVIATVPLFF-----------CIIAPFAKF 1318
Score = 32.3 bits (72), Expect = 3.3
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Query: 493 LLALVAIFFGMALYLRSLFLTLMVLLGVLGSL-LVAFFLYQVAFRMAYFPFVNLAALLLL 551
+L+L+ +A++ + L L VLL +LG + LV +Y + M ++L ++L+
Sbjct: 1188 VLSLLICVAAVAVFTTHILLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISL-SILVG 1246
Query: 552 SSVCANHTLIFFDLWRLSKSQLP----SGGLAQRVGRTM---HHFGYLLLVSGLTTSAA- 603
SSV ++ + + + L+ LP QR RT+ H G ++ S LTT A
Sbjct: 1247 SSV--DYCVHLVEGYLLAGENLPPHQAEDARTQRQWRTLEAVRHVGVAIVSSALTTVIAT 1304
Query: 604 ---FYASYLSRLPAVRCLALFMGTAVLVHLALTLVWL 637
F+ + +AL G ++L L ++ L
Sbjct: 1305 VPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALL 1341
>gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapiens]
Length = 1332
Score = 48.9 bits (115), Expect = 3e-05
Identities = 52/224 (23%), Positives = 90/224 (40%), Gaps = 11/224 (4%)
Query: 861 HSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGS-LAALVLQFQTNFRNSPDYNQ 919
H PW FL+ + +G + + G LA+ + + +NS DY +
Sbjct: 1009 HKYLPW----FLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLASRFMAYHKPLKNSQDYTE 1064
Query: 920 TQLFYNEVSHWLAAELGMAP---PGLRRGWFTSRLELYSLQHSLSTEPAVVLGLALALAF 976
E++ + A+L P P +T Y ++ E +L L L F
Sbjct: 1065 ALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTF 1124
Query: 977 AT--LLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEALFLSASVGLSVDFTV 1034
A LLLG ++ L ++ ++ ++ TVG + L N + L ++VG+SV+F
Sbjct: 1125 AVSCLLLGL-DLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVS 1183
Query: 1035 NYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLML 1078
+ S+ + P L R + A G A G+L+L
Sbjct: 1184 HITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVL 1227
Score = 38.5 bits (88), Expect = 0.046
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 12/149 (8%)
Query: 496 LVAIFFGMALYLRSLFLTLMV-LLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALL----- 549
++ ++ +AL S + +MV LG VA L V M +F ++ + + L
Sbjct: 642 VIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQV 701
Query: 550 ---LLSSVCANHTLIF-FDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFY 605
L+ SV A++ IF + RL + P +GR + +L+ L+ + F+
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRR--PGEPREVHIGRALGRVAPSMLLCSLSEAICFF 759
Query: 606 ASYLSRLPAVRCLALFMGTAVLVHLALTL 634
L+ +PAVR AL G AV++ L +
Sbjct: 760 LGALTPMPAVRTFALTSGLAVILDFLLQM 788
>gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]
Length = 340
Score = 46.6 bits (109), Expect = 2e-04
Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 29/189 (15%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPD-STQTKAVP---PEASPERSCSL 58
G S+ PAP P P+ + RP+ +P P+ TQ P E+ E+ +
Sbjct: 123 GSRLESAAPPEPAPEPAPQPDPRPDSQPTPKPALQPELPTQEDPTPEILSESVGEKQENG 182
Query: 59 HSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEY-------QGGSSLPGL 111
PL+ GP P + PS PA+ PR LQ+ + S PG
Sbjct: 183 AVVPLQAGDGEEGPAPEPHS----PPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPG- 237
Query: 112 GDRAALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVA 171
R +L H SS P +GT KP R + + S WPV
Sbjct: 238 SPRGSLSRHPSSQLAGPGVEGGEGTQKP-------------RDYIILAILSCFCPMWPVN 284
Query: 172 VLMLCLAVI 180
++ AV+
Sbjct: 285 IVAFAYAVM 293
>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
Length = 1278
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 16/158 (10%)
Query: 489 TVYPLLALVAIFFGMAL----YLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYFPFVN 544
TV A++ ++ +AL R L + V LG+ G L+V L VA + F ++
Sbjct: 623 TVVISYAIMFLYISLALGHIKSCRRLLVDSKVSLGIAGILIV---LSSVACSLGVFSYIG 679
Query: 545 LAALL--------LLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVS 596
L L L+ +V ++ I ++ + +L L Q++GR + + +S
Sbjct: 680 LPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDE-RLQGETLDQQLGRVLGEVAPSMFLS 738
Query: 597 GLTTSAAFYASYLSRLPAVRCLALFMGTAVLVHLALTL 634
+ + AF+ LS +PAV +LF G AV + L +
Sbjct: 739 SFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQI 776
>gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo sapiens]
Length = 1359
Score = 45.8 bits (107), Expect = 3e-04
Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 6/179 (3%)
Query: 905 LQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAP---PGLRRGWFTSRLELYSLQHSLS 961
+ + +NS DY + E++ + A+L P P +T Y ++
Sbjct: 1077 MAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTIL 1136
Query: 962 TEPAVVLGLALALAFAT--LLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEA 1019
E +L L L FA LLLG ++ L ++ ++ ++ TVG + L N
Sbjct: 1137 PEGLFMLSLCLVPTFAVSCLLLGL-DLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSL 1195
Query: 1020 LFLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLML 1078
+ L ++VG+SV+F + S+ + P L R + A G A G+L+L
Sbjct: 1196 INLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVL 1254
Score = 38.5 bits (88), Expect = 0.046
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 12/149 (8%)
Query: 496 LVAIFFGMALYLRSLFLTLMV-LLGVLGSLLVAFFLYQVAFRMAYFPFVNLAALL----- 549
++ ++ +AL S + +MV LG VA L V M +F ++ + + L
Sbjct: 642 VIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQV 701
Query: 550 ---LLSSVCANHTLIF-FDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTTSAAFY 605
L+ SV A++ IF + RL + P +GR + +L+ L+ + F+
Sbjct: 702 VPFLVLSVGADNIFIFVLEYQRLPRR--PGEPREVHIGRALGRVAPSMLLCSLSEAICFF 759
Query: 606 ASYLSRLPAVRCLALFMGTAVLVHLALTL 634
L+ +PAVR AL G AV++ L +
Sbjct: 760 LGALTPMPAVRTFALTSGLAVILDFLLQM 788
>gi|133922582 zinc finger protein 358 [Homo sapiens]
Length = 568
Score = 45.1 bits (105), Expect = 5e-04
Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 1/98 (1%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCP 62
G S +S G P PG GP P +PL +P T ++ P+A + L P
Sbjct: 451 GLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSP 510
Query: 63 LEDPSSSSGPPPTTS-TLQPVGPSSPLAPAHFTYPRAL 99
DP S P P S PV P +P T AL
Sbjct: 511 DLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPAL 548
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 44.3 bits (103), Expect = 8e-04
Identities = 34/99 (34%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 3 GDSSSSSGGSGPAPGPGP-EGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSC 61
GD GG+GP PGPGP G +P P AP GG P A RS ++
Sbjct: 12 GDGPLPPGGAGPGPGPGPGPGAGKP---PSAPAGGGQ--------LPAAGAARSTAVPPV 60
Query: 62 PLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQ 100
P P GP P ST + + P PL P Q
Sbjct: 61 PGPGPGPGPGPGP-GSTSRRLDPKEPLGNQRAASPTPKQ 98
Score = 35.8 bits (81), Expect = 0.30
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 9 SGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSS 68
+ G+ P GP+G +P G PL P SP ST+ +P +ASP+ S P + PSS
Sbjct: 547 ASGTSPLKQKGPQGLGQPSG-PL-PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSS 604
Score = 33.9 bits (76), Expect = 1.1
Identities = 35/127 (27%), Positives = 46/127 (36%), Gaps = 18/127 (14%)
Query: 1201 GPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQ--------DS 1252
GP +PP APA +L A + P + P GP P + +R+ +
Sbjct: 30 GPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQ 89
Query: 1253 QGEEAEPLPASPEAPAH-SPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPD 1311
+ P AS P H SP+ A P G + L V T S PS
Sbjct: 90 RAASPTPKQASATTPGHESPRETRAQGPAG-QEADGPRRTLQVDSRTQRSGRSPS----- 143
Query: 1312 SVGVSPD 1318
VSPD
Sbjct: 144 ---VSPD 147
Score = 31.6 bits (70), Expect = 5.6
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 6/46 (13%)
Query: 14 PAPGPGPEGEQ---RPEGEPLAP---DGGSPDSTQTKAVPPEASPE 53
PAPGPGP G + RP G P AP G +S +K +P A+ +
Sbjct: 3862 PAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQ 3907
Score = 31.2 bits (69), Expect = 7.3
Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 7 SSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEA---SPERSCSLHSCPL 63
S + SGPA G E + PE P A D GS + P ++ S E++ + +
Sbjct: 3176 SETSYSGPAVSSGYEQGKVPE-VPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMI 3234
Query: 64 EDPSS----SSGPPPTTSTLQPVGPSSPLAP 90
+D S S+ P + L+P+GP S P
Sbjct: 3235 DDISELTKDSTSTAPDSQRLEPLGPGSSGRP 3265
Score = 30.8 bits (68), Expect = 9.5
Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 1193 SEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDS 1252
+ DL H+ S+P APA P++ + + + SS Y A S K +RQ
Sbjct: 3671 ARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDS-KKGSRQAH 3729
Query: 1253 QGEEAEPLPASPEAPAHSPKAKAADPPDGFCSSAS 1287
G A A P+A +AA P S +S
Sbjct: 3730 SGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSS 3764
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/126 (27%), Positives = 45/126 (35%), Gaps = 11/126 (8%)
Query: 13 GPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGP 72
GP PGP G G P P GG + P+ P+ +H+ P + GP
Sbjct: 604 GPGGPPGPMGPGPNMGPP-GPMGGPMHPDMHPDMHPDMHPDMHADMHADMPMGPGMNPGP 662
Query: 73 P--PTTSTLQPVGPSS--------PLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSHGS 122
P P + P GP P+ PA Y Q+ +G PGL A H
Sbjct: 663 PMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQQEGMEMEPGLLGDAEDYGHYE 722
Query: 123 SLSPSP 128
L P
Sbjct: 723 ELPGEP 728
Score = 32.3 bits (72), Expect = 3.3
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 24/70 (34%)
Query: 8 SSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPS 67
+SGGSGP D G D +A+P + PE S LHS P+ PS
Sbjct: 876 ASGGSGPG------------------DSGPSDPRLARALPT-SKPEGS--LHSSPV-GPS 913
Query: 68 SS--SGPPPT 75
SS SGPPPT
Sbjct: 914 SSKGSGPPPT 923
Score = 31.2 bits (69), Expect = 7.3
Identities = 31/118 (26%), Positives = 39/118 (33%), Gaps = 5/118 (4%)
Query: 42 QTKAVPPEASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQE 101
QT + PP + E L S L DP G P + P P H
Sbjct: 827 QTSSRPPASVGE----LSSSGLGDPRLQKGHPTGSRLADPRLSRDPRLTRHVEASGGSGP 882
Query: 102 YQGGSSLPGLGDRAALCSHGSSLSPSPA-PSQRDGTWKPPAVQHHVVSVRQERAFQMP 158
G S P L SL SP PS G+ PP + +E+A +P
Sbjct: 883 GDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPPTEEEEGERALREKAVNIP 940
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/133 (27%), Positives = 47/133 (35%), Gaps = 15/133 (11%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCP 62
G ++ + G G AP P P G RP G P P S + VP A P + P
Sbjct: 74 GPAAPAEGAPGAAPEPPPAGRARPGGG--GPQRPGPPSPRRPLVP--AGPAPPAAKLRPP 129
Query: 63 LEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSHGS 122
E + S P P + + +P PA P AL G PG G
Sbjct: 130 PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP--------- 180
Query: 123 SLSPSPAPSQRDG 135
P P P + G
Sbjct: 181 --GPGPGPGKPAG 191
Score = 36.2 bits (82), Expect = 0.23
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 14 PAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGPP 73
P P P P RP G P P +P AVPP A+ + S + P P+ ++G P
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAP------AVPPPAAAQNGGSAGAAPA--PAPAAGGP 322
Query: 74 PTTSTLQPVGPSSPLAPA 91
S QP ++ APA
Sbjct: 323 AGVSG-QPGPGAAAAAPA 339
Score = 35.0 bits (79), Expect = 0.51
Identities = 41/157 (26%), Positives = 56/157 (35%), Gaps = 17/157 (10%)
Query: 1131 PWDAGTGDPGGEKAGRPRPG-SVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRP 1189
P AG P G A R G G PG +P + + + S A SH
Sbjct: 152 PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLN-SHHA 210
Query: 1190 SVLSEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRAR 1249
+ + L +++GP P P PA+P V P + ++P A PSP
Sbjct: 211 AAPAVSL-VNNGPAALLPLPKPAAPG-------TVIQTPPFVGAAAPPAPAAPSPPAAPA 262
Query: 1250 QDSQGEEAEPLPASPEA-------PAHSPKAKAADPP 1279
+ P P +P PA P A A PP
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 42.7 bits (99), Expect = 0.002
Identities = 49/150 (32%), Positives = 62/150 (41%), Gaps = 27/150 (18%)
Query: 12 SGPAPGPGPE----GEQRPEGEPLAPD--GGSPDSTQTKAV-------PPEASPERSCSL 58
S P P PE G + P PL + GGSP T + P EASP R S
Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
Query: 59 HSCPLEDPSSSSG----PPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDR 114
P + P SSS P P + + SSP +P P + +E SS P +R
Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI---SSSPTSKNR 462
Query: 115 AALCSHGSS---LSPSPAPSQRDGTWKPPA 141
SHG + S S PS+R G + PA
Sbjct: 463 ----SHGRAKRDKSHSHTPSRRMGRSRSPA 488
Score = 41.2 bits (95), Expect = 0.007
Identities = 43/138 (31%), Positives = 50/138 (36%), Gaps = 12/138 (8%)
Query: 4 DSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPL 63
DS S G PE + +P P A GS S + KA P A P RS S S
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRA-QSGSDSSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 64 EDPS--------SSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
PS SS PP + T + SSP T R + S P L +A
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK---TKSRTPPRRRSSRSSPELTRKA 1701
Query: 116 ALCSHGSSLSPSPAPSQR 133
L S S SP R
Sbjct: 1702 RLSRRSRSASSSPETRSR 1719
Score = 40.0 bits (92), Expect = 0.016
Identities = 63/258 (24%), Positives = 85/258 (32%), Gaps = 45/258 (17%)
Query: 1147 PRPG----SVGGMPGSCSEQYE-----LQPLARRRSPSFDTSTATSKLSHRPSVLSED-- 1195
P PG VG P S Q LQP RRS S +S+++S S S S
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556
Query: 1196 -----------LQLHDGPCCSRPPPAPASPRELLLDHQ------------------AVFS 1226
L + R P +P+E + + + + S
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 1227 QCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPLPASPEAPAHSPKAKAADPPDGFCSSA 1286
+ +SS + S + + S + P PA P A A PP G S
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Query: 1287 STLEGL-SVSDETCLSTSEPSARVPDSVGVSPDDLDDTGQPVLERGQLNGKRDTLWLALR 1345
S + + S+ D LS S R P D + + RGQ R R
Sbjct: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Query: 1346 ETVYDPS-LPASHHSSLS 1362
ET PS P H SS S
Sbjct: 2737 ET---PSPRPMRHRSSRS 2751
Score = 39.7 bits (91), Expect = 0.021
Identities = 41/153 (26%), Positives = 54/153 (35%), Gaps = 22/153 (14%)
Query: 6 SSSSGGSG----PAPGPGPEGEQRPEG------EPLAP-DGGSPDSTQTKAVPPEASPER 54
S +SG G P PG QRP +P +P + D + A P SPER
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER 356
Query: 55 SCSLHSCPLEDP----SSSSGPPPTTST---LQPVGPSSPLAPAHF----TYPRALQEYQ 103
S + P P P P +T +PV P S +P P L +
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS 416
Query: 104 GGSSLPGLGDRAALCSHGSSLSPSPAPSQRDGT 136
S P + H SS SP P+ G+
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Score = 32.7 bits (73), Expect = 2.5
Identities = 43/158 (27%), Positives = 53/158 (33%), Gaps = 31/158 (19%)
Query: 3 GDSSSSSGGSG------------PAPGPGPEGEQRPEGEPLAP-------------DGGS 37
G SSS S GS P+P P P+ R EG P P S
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR-EGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 38 PDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPR 97
S+ + + +S S S S SSSS P P+SP P P
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP----PG 2671
Query: 98 ALQEYQGGSSLPGLGDRAALC-SHGSSLSPSPAPSQRD 134
+ + L D +L S PSP PS RD
Sbjct: 2672 ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD 2709
Score = 31.2 bits (69), Expect = 7.3
Identities = 26/105 (24%), Positives = 34/105 (32%), Gaps = 3/105 (2%)
Query: 35 GGSPDSTQTKAVPPEASPERSCSLHS---CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPA 91
G SP Q PP S S + P SSS PPP + P S +
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Query: 92 HFTYPRALQEYQGGSSLPGLGDRAALCSHGSSLSPSPAPSQRDGT 136
H QG + P +++ S SP P + T
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885
Score = 30.8 bits (68), Expect = 9.5
Identities = 41/142 (28%), Positives = 47/142 (33%), Gaps = 20/142 (14%)
Query: 7 SSSGGSGPAPGPGPEGEQRPEGEPLAP---------DGGSPDSTQTKAVPPEASPERSCS 57
S SG S GP PEG E P P SP+ PP RS
Sbjct: 1636 SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695
Query: 58 --LHSCPLEDPS-SSSGPPPTTSTLQPVGPSSP--LAPAHFTYPRALQEYQGGSSLPGLG 112
L S S+S P T S P SP +P R+ + + SS
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS----- 1750
Query: 113 DRAALCS-HGSSLSPSPAPSQR 133
R S G S SP P QR
Sbjct: 1751 PRTKTTSRRGRSPSPKPRGLQR 1772
>gi|190341097 rhomboid family 1 [Homo sapiens]
Length = 855
Score = 42.4 bits (98), Expect = 0.003
Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 33/162 (20%)
Query: 250 APRGSAQ----ESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAI 305
AP G +Q +S +R R + E ++ +QENF+ GP SS +L +L A
Sbjct: 428 APVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGP-------------SSEALIHLGAK 474
Query: 306 HSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQADAARTL 365
S C + Q+ H+ + +R + CC V ++RS C+ T++ + + TL
Sbjct: 475 FSPCMRQDPQV--HSFIRSAREREKHSACC----------VRNDRSGCVQTSEEECSSTL 522
Query: 366 ALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSA 407
A+ + H A P G + C Q P C + S+
Sbjct: 523 AVWVKWPI--HPSA--PELAGHKRQFGSVCHQDPRVCDEPSS 560
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 42.4 bits (98), Expect = 0.003
Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 9/111 (8%)
Query: 2 DGDSSSSSGGSGPAPGPGPEGEQRPEGEP--------LAPDGGSPDSTQTKAVPPEASPE 53
D S SS G GP P+G +P+G P P GG+ P+ P
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 226
Query: 54 RSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQG 104
+ + P GPPP QP GP P P+ + QG
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQG 276
Score = 40.0 bits (92), Expect = 0.016
Identities = 35/126 (27%), Positives = 44/126 (34%), Gaps = 21/126 (16%)
Query: 13 GPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSGP 72
G GP P+G +P+G P P G + + PP+ RS P P GP
Sbjct: 76 GKPQGPPPQGGNKPQGPP--PPG------KPQGPPPQGDKSRS------PRSPPGKPQGP 121
Query: 73 PPTTSTLQPVGPSSPLAPAHFTYPRALQEYQG------GSSLPGLGDRAALCSHGSSLSP 126
PP QP GP P P+ + QG P GD + S P
Sbjct: 122 PPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP 180
Query: 127 SPAPSQ 132
P Q
Sbjct: 181 QGPPPQ 186
Score = 39.7 bits (91), Expect = 0.021
Identities = 26/86 (30%), Positives = 36/86 (41%), Gaps = 9/86 (10%)
Query: 13 GPAPGPGPEGEQRPEGEP-------LAPDGGSPD-STQTKAVPPEASPERSCSLHSCPLE 64
G GP P+G +P+G P P GGS S+++ P+ P + + P
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP 320
Query: 65 DPSSSSGPPPTTSTLQPVGPSSPLAP 90
P GPPP +P GP P P
Sbjct: 321 PPGKPQGPPPQGGN-KPQGPPPPGKP 345
Score = 38.5 bits (88), Expect = 0.046
Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 10/111 (9%)
Query: 3 GDSSSSSGGS-GPAPGPGPEGEQRPEGEP--------LAPDGGSPDSTQTKAVPPEASPE 53
GD S S G GP P+G +P+G P P GG+ P+ P
Sbjct: 105 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164
Query: 54 RSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQG 104
+ + P GPPP QP GP P P+ + QG
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQG 214
Score = 36.2 bits (82), Expect = 0.23
Identities = 25/91 (27%), Positives = 31/91 (34%), Gaps = 9/91 (9%)
Query: 5 SSSSSGGSGPAPGPGPEGEQRPEGEP--------LAPDGGSPDSTQTKAVPPEASPERSC 56
S SS G GP P+G +P+G P P GG+ P+ P +
Sbjct: 294 SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 353
Query: 57 SLHSCPLEDPSSSSGPPPTTSTLQPVGPSSP 87
S P GPP P GP P
Sbjct: 354 SKSRSARSPPGKPQGPPQQEGN-NPQGPPPP 383
Score = 33.9 bits (76), Expect = 1.1
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 6/103 (5%)
Query: 11 GSGPAPGPGPEGEQRPEGEPLAP---DGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPS 67
G+ P G P+G P G+P P G P P+ P + + P P
Sbjct: 38 GAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPG 96
Query: 68 SSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPG 110
GPPP + P SP P+ + QG PG
Sbjct: 97 KPQGPPPQGDKSR--SPRSPPGKPQGPPPQGGNQPQGPPPPPG 137
Score = 32.7 bits (73), Expect = 2.5
Identities = 21/79 (26%), Positives = 29/79 (36%), Gaps = 13/79 (16%)
Query: 12 SGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDPSSSSG 71
+G G P+G +P+G P P P+ P + + P P G
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPPG------------KPQGPPPQGGNQPQGPPPPPGKPQG 80
Query: 72 PPPTTSTLQPVGPSSPLAP 90
PPP +P GP P P
Sbjct: 81 PPPQGGN-KPQGPPPPGKP 98
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 42.4 bits (98), Expect = 0.003
Identities = 41/130 (31%), Positives = 49/130 (37%), Gaps = 19/130 (14%)
Query: 5 SSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLE 64
S S GP PGPGP+G EPL DS Q + PP +P S
Sbjct: 723 SPSLKTPDGPVPGPGPQG---AAPEPLGA-SVQRDSAQGRPCPPPQAPANQPEGASSAA- 777
Query: 65 DPSSSSGPPPTTSTLQPV--GPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSHGS 122
P S PPT ++ PV GP+ P+ P GG LG A HG
Sbjct: 778 -PGSPVPAPPTKASALPVEQGPAEPIPPG---------VASGGLRPDALGPTTA--HHGP 825
Query: 123 SLSPSPAPSQ 132
P P S+
Sbjct: 826 RHPPKPPRSK 835
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/172 (25%), Positives = 56/172 (32%), Gaps = 23/172 (13%)
Query: 3 GDSSSSSGGSGPAPGPGPEGEQRPEG------EPLAPDGGSPDST-QTKAVPPEASPERS 55
G G GP PGP P RP G P P G P Q PP+ PE
Sbjct: 229 GPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGP 288
Query: 56 CSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRA 115
+ + P P PP T P P+ P A + P+ Q P
Sbjct: 289 MANAAAPTSTPQKLI-PPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAP----MV 343
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAE 167
L S ++P P D V + QER +++ + I E
Sbjct: 344 PLHQKQSRITPIQKPRGLD-----------PVEILQEREYRLQARIAHRIQE 384
Score = 33.5 bits (75), Expect = 1.5
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 11/143 (7%)
Query: 1 MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS 60
M G S G +G P P P +Q +G P G S+ A P + P+ S
Sbjct: 93 MKGMGMRSGGHAGMGPPPSPM-DQHSQGYPSPLGGSEHASSPVPASGPSSGPQMSSGPGG 151
Query: 61 CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRA-LQEYQGGSSLPGLGDRAALCS 119
PL+ G P Q GP +P RA + Y+ + L D +
Sbjct: 152 APLD------GADPQALGQQNRGP-TPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAV 204
Query: 120 HGSSLSPSPAPSQRDGTWKPPAV 142
G P P Q+ T PP+V
Sbjct: 205 QGK--RPMPGMQQQMPTLPPPSV 225
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 42.0 bits (97), Expect = 0.004
Identities = 41/142 (28%), Positives = 50/142 (35%), Gaps = 6/142 (4%)
Query: 5 SSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLE 64
SSSS + P P P + P P G+ S +AVPP + S P
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 65 DPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSS----LPGLGDRAALCSH 120
SS + PPP + P P + + PR Q SS LP G L
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 121 GSSLSPSPA--PSQRDGTWKPP 140
S P P P R G PP
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPP 382
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/145 (30%), Positives = 51/145 (35%), Gaps = 28/145 (19%)
Query: 8 SSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQ---------TKAVPPEASPERSCSL 58
S+ P P P P RP PL P D T + + PP SP R
Sbjct: 301 SASSQAPPPPPPPS---RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR---- 353
Query: 59 HSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPG---LGDRA 115
S PL P S PPP P G S PL P P + +LP L R+
Sbjct: 354 -SGPLPPPPSERPPPPVR---DPPGRSGPLPPP----PPVSRNGSTSRALPATPQLPSRS 405
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPP 140
+ S S P P P R PP
Sbjct: 406 GVDSPRSGPRP-PLPPDRPSAGAPP 429
Score = 33.9 bits (76), Expect = 1.1
Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 23/155 (14%)
Query: 5 SSSSSGGSGPAPGPG----PEGEQRPEGEPLAPDGGS-PDSTQTKAVPPEASPERSCSLH 59
S S G P P PG P QR P PD GS PDS PP S R
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP----PPVPSTPR----- 192
Query: 60 SCPLEDPSSSSGPPPTTSTLQPVGPSSPL-APAHFTYPRALQEYQGGSSL-PGLGDRAAL 117
P++ + G PP P GP P P +P GG S+ ++
Sbjct: 193 --PIQSSPHNRGSPPV-----PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Query: 118 CSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQE 152
S+ L P+P+ + D PP + S+ +E
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280
Score = 31.6 bits (70), Expect = 5.6
Identities = 38/138 (27%), Positives = 46/138 (33%), Gaps = 36/138 (26%)
Query: 7 SSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDP 66
S S + P P PG G PL P PP P P+ DP
Sbjct: 340 SLSSSTPPLPSPGRSG-------PLPP-------------PPSERPPP-------PVRDP 372
Query: 67 SSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAAL----CSHGS 122
SGP P + G +S PA P + G P G R L S G+
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPS-----RSGVDSPRSGPRPPLPPDRPSAGA 427
Query: 123 SLSPSPAPSQRDGTWKPP 140
P P+ S R+G P
Sbjct: 428 PPPPPPSTSIRNGFQDSP 445
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 42.0 bits (97), Expect = 0.004
Identities = 41/142 (28%), Positives = 50/142 (35%), Gaps = 6/142 (4%)
Query: 5 SSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLE 64
SSSS + P P P + P P G+ S +AVPP + S P
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 65 DPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSS----LPGLGDRAALCSH 120
SS + PPP + P P + + PR Q SS LP G L
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 121 GSSLSPSPA--PSQRDGTWKPP 140
S P P P R G PP
Sbjct: 361 PSERPPPPVRDPPGRSGPLPPP 382
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/145 (30%), Positives = 51/145 (35%), Gaps = 28/145 (19%)
Query: 8 SSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQ---------TKAVPPEASPERSCSL 58
S+ P P P P RP PL P D T + + PP SP R
Sbjct: 301 SASSQAPPPPPPPS---RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR---- 353
Query: 59 HSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPG---LGDRA 115
S PL P S PPP P G S PL P P + +LP L R+
Sbjct: 354 -SGPLPPPPSERPPPPVR---DPPGRSGPLPPP----PPVSRNGSTSRALPATPQLPSRS 405
Query: 116 ALCSHGSSLSPSPAPSQRDGTWKPP 140
+ S S P P P R PP
Sbjct: 406 GVDSPRSGPRP-PLPPDRPSAGAPP 429
Score = 33.9 bits (76), Expect = 1.1
Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 23/155 (14%)
Query: 5 SSSSSGGSGPAPGPG----PEGEQRPEGEPLAPDGGS-PDSTQTKAVPPEASPERSCSLH 59
S S G P P PG P QR P PD GS PDS PP S R
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP----PPVPSTPR----- 192
Query: 60 SCPLEDPSSSSGPPPTTSTLQPVGPSSPL-APAHFTYPRALQEYQGGSSL-PGLGDRAAL 117
P++ + G PP P GP P P +P GG S+ ++
Sbjct: 193 --PIQSSPHNRGSPPV-----PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Query: 118 CSHGSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQE 152
S+ L P+P+ + D PP + S+ +E
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHRE 280
Score = 31.6 bits (70), Expect = 5.6
Identities = 38/138 (27%), Positives = 46/138 (33%), Gaps = 36/138 (26%)
Query: 7 SSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHSCPLEDP 66
S S + P P PG G PL P PP P P+ DP
Sbjct: 340 SLSSSTPPLPSPGRSG-------PLPP-------------PPSERPPP-------PVRDP 372
Query: 67 SSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAAL----CSHGS 122
SGP P + G +S PA P + G P G R L S G+
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPS-----RSGVDSPRSGPRPPLPPDRPSAGA 427
Query: 123 SLSPSPAPSQRDGTWKPP 140
P P+ S R+G P
Sbjct: 428 PPPPPPSTSIRNGFQDSP 445
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 41.6 bits (96), Expect = 0.005
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 21/135 (15%)
Query: 14 PAPGPGPEGEQRPEGEPLAP------------DGGSPDSTQTKAVPPEASPERSCSLHSC 61
PAP P P G+ +P+ P P P +T P ASP R
Sbjct: 725 PAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR------V 778
Query: 62 PLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYP-RALQEYQGGSSLPGLGDRAALCSH 120
P +P S G T S L P G SSPL P + P + + Q +S P + +
Sbjct: 779 PPREPLSPQG-SRTPSPLVPPG-SSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAP 836
Query: 121 GSSLSPSPAPSQRDG 135
G P P RDG
Sbjct: 837 GPRAGPCILPIVRDG 851
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 41.6 bits (96), Expect = 0.005
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 21/135 (15%)
Query: 14 PAPGPGPEGEQRPEGEPLAP------------DGGSPDSTQTKAVPPEASPERSCSLHSC 61
PAP P P G+ +P+ P P P +T P ASP R
Sbjct: 803 PAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPR------V 856
Query: 62 PLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYP-RALQEYQGGSSLPGLGDRAALCSH 120
P +P S G T S L P G SSPL P + P + + Q +S P + +
Sbjct: 857 PPREPLSPQG-SRTPSPLVPPG-SSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAP 914
Query: 121 GSSLSPSPAPSQRDG 135
G P P RDG
Sbjct: 915 GPRAGPCILPIVRDG 929
>gi|148612857 sickle tail isoform 3 [Homo sapiens]
Length = 1309
Score = 41.6 bits (96), Expect = 0.005
Identities = 66/246 (26%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 1167 PLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFS 1226
P A P D +LS +DL+ G PPP P PR L + +
Sbjct: 973 PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGG---KSPPPPPPPPRRSYLPGSGLTT 1029
Query: 1227 QCPA----------LQTSSPYKQAGPSPKTRARQDSQGEEAEP-LPASPEAPAHSPKAKA 1275
+ + + AGPSP+TRA + E A P+ P S K +
Sbjct: 1030 TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEE 1089
Query: 1276 ADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDLDDTG-----QPVLER 1330
+ +G A L+G S + +T VP S P LD G Q +
Sbjct: 1090 EEEEEGDKIMAE-LQGSSGAPQT------SRMPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1142
Query: 1331 GQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNSQPD---LPDV 1387
Q NG + T PSLPAS +LS P G LP+S D LP+
Sbjct: 1143 RQANGSAKKSGGDFKPT--SPSLPASKIPALS------PSSGKSSSLPSSSGDSSNLPNP 1194
Query: 1388 WLRRPS 1393
+PS
Sbjct: 1195 PATKPS 1200
Score = 32.7 bits (73), Expect = 2.5
Identities = 40/155 (25%), Positives = 52/155 (33%), Gaps = 28/155 (18%)
Query: 10 GGSGPAPGPGPEGEQRPEGEPLAPDG-------GSPDSTQTKAVPPEASPERSCSLHSCP 62
GG P P P P G L G ++ KA +A P P
Sbjct: 1006 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1065
Query: 63 LEDPSSS---SGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCS 119
E+P+S+ S PP TTS+ S + + E QG S P
Sbjct: 1066 AEEPASAWTPSPPPVTTSS------SKDEEEEEEEGDKIMAELQGSSGAP---------- 1109
Query: 120 HGSSLSPSP-APSQRDGTWKPPAVQHHVVSVRQER 153
+S P P + R GT P Q + RQ R
Sbjct: 1110 -QTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR 1143
>gi|148612813 sickle tail isoform 2 [Homo sapiens]
Length = 1264
Score = 41.6 bits (96), Expect = 0.005
Identities = 66/246 (26%), Positives = 89/246 (36%), Gaps = 37/246 (15%)
Query: 1167 PLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHDGPCCSRPPPAPASPRELLLDHQAVFS 1226
P A P D +LS +DL+ G PPP P PR L + +
Sbjct: 928 PPATGPLPRGDAPVDKVELSEDSPNSEQDLEKLGG---KSPPPPPPPPRRSYLPGSGLTT 984
Query: 1227 QCPA----------LQTSSPYKQAGPSPKTRARQDSQGEEAEP-LPASPEAPAHSPKAKA 1275
+ + + AGPSP+TRA + E A P+ P S K +
Sbjct: 985 TRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEE 1044
Query: 1276 ADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDLDDTG-----QPVLER 1330
+ +G A L+G S + +T VP S P LD G Q +
Sbjct: 1045 EEEEEGDKIMAE-LQGSSGAPQT------SRMPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1097
Query: 1331 GQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNSQPD---LPDV 1387
Q NG + T PSLPAS +LS P G LP+S D LP+
Sbjct: 1098 RQANGSAKKSGGDFKPT--SPSLPASKIPALS------PSSGKSSSLPSSSGDSSNLPNP 1149
Query: 1388 WLRRPS 1393
+PS
Sbjct: 1150 PATKPS 1155
Score = 32.7 bits (73), Expect = 2.5
Identities = 40/155 (25%), Positives = 52/155 (33%), Gaps = 28/155 (18%)
Query: 10 GGSGPAPGPGPEGEQRPEGEPLAPDG-------GSPDSTQTKAVPPEASPERSCSLHSCP 62
GG P P P P G L G ++ KA +A P P
Sbjct: 961 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 1020
Query: 63 LEDPSSS---SGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCS 119
E+P+S+ S PP TTS+ S + + E QG S P
Sbjct: 1021 AEEPASAWTPSPPPVTTSS------SKDEEEEEEEGDKIMAELQGSSGAP---------- 1064
Query: 120 HGSSLSPSP-APSQRDGTWKPPAVQHHVVSVRQER 153
+S P P + R GT P Q + RQ R
Sbjct: 1065 -QTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYR 1098
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 41.6 bits (96), Expect = 0.005
Identities = 43/161 (26%), Positives = 55/161 (34%), Gaps = 30/161 (18%)
Query: 3 GDSSSSSGGS-GPAPGPGPEGEQRPEGEPLAP-------------DGGSPDSTQTKAVPP 48
GD S S G GP P+G +P+G P P G P + + PP
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 49 EASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQG---- 104
+ RS P P GPPP QP GP P P+ ++ QG
Sbjct: 144 QGDKSRS------PRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 105 ----GSSLPGLGDRAALCSHGSSLSPSP-APSQRDGTWKPP 140
G G R++ G P P +Q G PP
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Score = 41.2 bits (95), Expect = 0.007
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 8/85 (9%)
Query: 13 GPAPGPGPEGEQRPEGEPLA-------PDGGSPDSTQTKAVPPEASPERSCSLHSCPLED 65
G GP P+G ++P+G P P G S+Q+ P+ P + + P
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
Query: 66 PSSSSGPPPTTSTLQPVGPSSPLAP 90
P GPPP +P GP P P
Sbjct: 237 PGKPQGPPPQGGN-KPQGPPPPGKP 260
Score = 40.0 bits (92), Expect = 0.016
Identities = 26/89 (29%), Positives = 33/89 (37%), Gaps = 20/89 (22%)
Query: 12 SGPAPGPGPEGEQRPEGEPLAP-------------DGGSPDSTQTKAVPPEASPERSCSL 58
+G GP P+G +P+G P P G P + + PP+ RS
Sbjct: 33 AGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS--- 89
Query: 59 HSCPLEDPSSSSGPPPTTSTLQPVGPSSP 87
P P GPPP QP GP P
Sbjct: 90 ---PRSPPGKPQGPPPQGGN-QPQGPPPP 114
Score = 38.9 bits (89), Expect = 0.035
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 17/100 (17%)
Query: 7 SSSGGS---GPAPGPG------PEGEQRPEGEPLA-------PDGGSPDSTQTKAVPPEA 50
S GG+ GP P PG P+G +P+G P P G S ++ P+
Sbjct: 40 SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 99
Query: 51 SPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAP 90
P + + P P GPPP +P GP P P
Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGN-RPQGPPPPGKP 138
Score = 38.1 bits (87), Expect = 0.060
Identities = 32/116 (27%), Positives = 40/116 (34%), Gaps = 21/116 (18%)
Query: 3 GDSSSSSGGS-GPAPGPGPEGEQRPEGEPLAPDG-------------GSPDSTQTKAVPP 48
GD S S G GP P+G +P+G P P G P + + PP
Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPP 204
Query: 49 EASPERSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQG 104
+ RS P GPPP QP GP P P+ + QG
Sbjct: 205 QGDKSRSSQ------SPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQG 253
Score = 37.4 bits (85), Expect = 0.10
Identities = 27/94 (28%), Positives = 33/94 (35%), Gaps = 10/94 (10%)
Query: 3 GDSS-SSSGGSGPAPGPGPEGEQRPEGEP--------LAPDGGSPDSTQTKAVPPEASPE 53
GD S SS G GP P+G +P+G P P GG+ P+ P
Sbjct: 206 GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA 265
Query: 54 RSCSLHSCPLEDPSSSSGPPPTTSTLQPVGPSSP 87
+ S P GPP P GP P
Sbjct: 266 QGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPP 298
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 41.6 bits (96), Expect = 0.005
Identities = 42/135 (31%), Positives = 59/135 (43%), Gaps = 20/135 (14%)
Query: 5 SSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKA------VPPEASPERS--C 56
+S+SS AP PE P GEP PDG + +A + P ASP+R
Sbjct: 744 ASASSSLLLLAPARAPEQPPAP-GEP-TPDGRLYAARPGRASHGDFPLTPHASPDRRRVV 801
Query: 57 SLHSCPLEDPSSSSG------PPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPG 110
S + PL+ S++ G PPPT S +P+GP +P A R + G + PG
Sbjct: 802 SAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPAAT----LRRTHTFNSGEARPG 857
Query: 111 LGDRAALCSHGSSLS 125
R G+ L+
Sbjct: 858 DRHRGCHARPGTDLA 872
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,722,405
Number of Sequences: 37866
Number of extensions: 3620948
Number of successful extensions: 24286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 18385
Number of HSP's gapped (non-prelim): 5712
length of query: 1401
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1286
effective length of database: 13,892,928
effective search space: 17866305408
effective search space used: 17866305408
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.