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Search of human proteins with 121583483
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
(2098 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 4244 0.0
gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III i... 694 0.0
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 99 6e-20
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 99 6e-20
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 99 6e-20
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 81 9e-15
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 74 2e-12
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 71 1e-11
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 71 1e-11
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 69 5e-11
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 68 1e-10
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 67 1e-10
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 67 1e-10
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 67 1e-10
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 67 2e-10
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 67 2e-10
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 66 3e-10
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 65 5e-10
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 65 9e-10
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 64 2e-09
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 62 6e-09
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 62 6e-09
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 62 8e-09
gi|217272865 myotubularin related protein 4 [Homo sapiens] 61 1e-08
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 61 1e-08
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 61 1e-08
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 59 4e-08
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 59 7e-08
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 59 7e-08
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 57 2e-07
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 4244 bits (11006), Expect = 0.0
Identities = 2098/2098 (100%), Positives = 2098/2098 (100%)
Query: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA
Sbjct: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
Query: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGH 120
EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGH
Sbjct: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGH 120
Query: 121 DPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHC 180
DPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHC
Sbjct: 121 DPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHC 180
Query: 181 RLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSA 240
RLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSA
Sbjct: 181 RLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSA 240
Query: 241 CSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSP 300
CSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSP
Sbjct: 241 CSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSP 300
Query: 301 ARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWK 360
ARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWK
Sbjct: 301 ARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWK 360
Query: 361 KICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLD 420
KICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLD
Sbjct: 361 KICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLD 420
Query: 421 CVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQI 480
CVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQI
Sbjct: 421 CVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQI 480
Query: 481 AEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPH 540
AEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPH
Sbjct: 481 AEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPH 540
Query: 541 PADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENG 600
PADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENG
Sbjct: 541 PADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENG 600
Query: 601 EKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMD 660
EKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMD
Sbjct: 601 EKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMD 660
Query: 661 IRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETK 720
IRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETK
Sbjct: 661 IRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETK 720
Query: 721 FTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVL 780
FTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVL
Sbjct: 721 FTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVL 780
Query: 781 ERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIK 840
ERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIK
Sbjct: 781 ERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIK 840
Query: 841 LRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEG 900
LRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEG
Sbjct: 841 LRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEG 900
Query: 901 AVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHST 960
AVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHST
Sbjct: 901 AVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHST 960
Query: 961 TACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQ 1020
TACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQ
Sbjct: 961 TACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQ 1020
Query: 1021 DDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDY 1080
DDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDY
Sbjct: 1021 DDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDY 1080
Query: 1081 FAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAE 1140
FAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAE
Sbjct: 1081 FAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAE 1140
Query: 1141 HLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSD 1200
HLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSD
Sbjct: 1141 HLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSD 1200
Query: 1201 AVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLER 1260
AVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLER
Sbjct: 1201 AVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLER 1260
Query: 1261 YCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICK 1320
YCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICK
Sbjct: 1261 YCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICK 1320
Query: 1321 QVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASF 1380
QVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASF
Sbjct: 1321 QVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASF 1380
Query: 1381 SYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFS 1440
SYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFS
Sbjct: 1381 SYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFS 1440
Query: 1441 KTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEV 1500
KTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEV
Sbjct: 1441 KTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEV 1500
Query: 1501 LQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDR 1560
LQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDR
Sbjct: 1501 LQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDR 1560
Query: 1561 FLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKE 1620
FLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKE
Sbjct: 1561 FLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKE 1620
Query: 1621 KSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEY 1680
KSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEY
Sbjct: 1621 KSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEY 1680
Query: 1681 RNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKA 1740
RNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKA
Sbjct: 1681 RNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKA 1740
Query: 1741 SGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQ 1800
SGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQ
Sbjct: 1741 SGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQ 1800
Query: 1801 KKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGG 1860
KKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGG
Sbjct: 1801 KKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGG 1860
Query: 1861 KSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIG 1920
KSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIG
Sbjct: 1861 KSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIG 1920
Query: 1921 YKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLL 1980
YKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLL
Sbjct: 1921 YKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLL 1980
Query: 1981 KMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRT 2040
KMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRT
Sbjct: 1981 KMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRT 2040
Query: 2041 FTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC 2098
FTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC
Sbjct: 2041 FTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC 2098
>gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 3 [Homo sapiens]
Length = 451
Score = 694 bits (1791), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 205 GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI 264
GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI
Sbjct: 108 GDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNI 167
Query: 265 FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY 324
FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY
Sbjct: 168 FLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSY 227
Query: 325 ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC 384
ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC
Sbjct: 228 ETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNC 287
Query: 385 IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF 444
IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF
Sbjct: 288 IVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEF 347
Query: 445 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 504
SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ
Sbjct: 348 SETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQ 407
Query: 505 STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK 545
STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK
Sbjct: 408 STVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQK 448
Score = 221 bits (564), Expect = 4e-57
Identities = 108/111 (97%), Positives = 108/111 (97%)
Query: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA
Sbjct: 1 MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERA 60
Query: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRR 111
EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSAL R
Sbjct: 61 EGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALGDLR 111
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 98.6 bits (244), Expect = 6e-20
Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)
Query: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690
S W + ++ V+ V+ + +N ++DI+++ ++KIPGG DS V+ G + K++
Sbjct: 165 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 223
Query: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744
H +M IKNP+I+LL S+EY E T+ I+ E E+++ + I+
Sbjct: 224 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 283
Query: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804
++P +V+ EK +S +AQ L+ IT + V+ RI+R G ++S + L + +
Sbjct: 284 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 342
Query: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856
GT ++I ++ +E F C CTI LRG S L+ V+ L
Sbjct: 343 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 390
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 98.6 bits (244), Expect = 6e-20
Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)
Query: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690
S W + ++ V+ V+ + +N ++DI+++ ++KIPGG DS V+ G + K++
Sbjct: 128 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 186
Query: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744
H +M IKNP+I+LL S+EY E T+ I+ E E+++ + I+
Sbjct: 187 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 246
Query: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804
++P +V+ EK +S +AQ L+ IT + V+ RI+R G ++S + L + +
Sbjct: 247 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 305
Query: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856
GT ++I ++ +E F C CTI LRG S L+ V+ L
Sbjct: 306 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 353
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 98.6 bits (244), Expect = 6e-20
Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)
Query: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690
S W + ++ V+ V+ + +N ++DI+++ ++KIPGG DS V+ G + K++
Sbjct: 166 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 224
Query: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744
H +M IKNP+I+LL S+EY E T+ I+ E E+++ + I+
Sbjct: 225 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 284
Query: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804
++P +V+ EK +S +AQ L+ IT + V+ RI+R G ++S + L + +
Sbjct: 285 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 343
Query: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856
GT ++I ++ +E F C CTI LRG S L+ V+ L
Sbjct: 344 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 391
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 81.3 bits (199), Expect = 9e-15
Identities = 40/126 (31%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
W+PD +C+ C C KF R+HHCR CG+ FC RCC+Q++P + M + +R C C
Sbjct: 41 WVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAECA 100
Query: 215 KIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKAS--RNIFLEDDLAW 272
++L A D + L L A + SE + R ++ R +FL+ D +
Sbjct: 101 LVSLKEAEFYD-----KQLKVLLSGATFLVTFGNSEKPETMTCRLSNNQRYLFLDGDSHY 155
Query: 273 Q-SLIH 277
+ ++H
Sbjct: 156 EIEIVH 161
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 73.9 bits (180), Expect = 2e-12
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Query: 142 MEGKSQDSDLKQ--YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGK 199
+ K++D D + W+PD C C C FT RR+HHCR CG+IFCSRC + P
Sbjct: 799 LAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLP 858
Query: 200 FMGYTGDLRACTYC 213
G +R CT+C
Sbjct: 859 RYGQVKPVRVCTHC 872
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 71.2 bits (173), Expect = 1e-11
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYC- 213
W+PDS+ C +C KFT +RRHHCR CG++FC CCN++ K + R C C
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC--KLQYLEKEARVCVVCY 801
Query: 214 RKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRT 253
I+ + A + G +L + C+ +V P E +T
Sbjct: 802 ETISKAQAFERMMSPTGSNLKSNHSDECT-TVQPPQENQT 840
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 71.2 bits (173), Expect = 1e-11
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYC- 213
W+PDS+ C +C KFT +RRHHCR CG++FC CCN++ K + R C C
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC--KLQYLEKEARVCVVCY 801
Query: 214 RKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRT 253
I+ + A + G +L + C+ +V P E +T
Sbjct: 802 ETISKAQAFERMMSPTGSNLKSNHSDECT-TVQPPQENQT 840
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 68.9 bits (167), Expect = 5e-11
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
W+PDSQ C C +FT +RRHHCR CG++FC+ CC+ + +M + R C C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
Query: 215 KIALSYAHSTDSNSI 229
+ ++ A + +
Sbjct: 755 SVLMNVAQPREQRRV 769
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 67.8 bits (164), Expect = 1e-10
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 147 QDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGD 206
QD+++ + W+PD CY C F R+HHCR CG +FCS CCNQ++P
Sbjct: 1109 QDTEMTR-WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEP 1167
Query: 207 LRACTYCRKIALSYAHSTDSN 227
R C C S H T S+
Sbjct: 1168 SRVCKSC----YSSLHPTSSS 1184
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 67.4 bits (163), Expect = 1e-10
Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 47 SSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSA 106
SS + KE+ + Q E Q TS L Q V ++L +E
Sbjct: 437 SSLEKELKSEKEQRQALQRELQHEKD--TSSLLRMELQQVEGLKKELRELQDEKAELQKI 494
Query: 107 LDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYD 166
+ + +A G H ++ +++ + V + LK W+ D + C
Sbjct: 495 CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKG------------HAWLKDDEATHCRQ 542
Query: 167 CSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDS 226
C ++F+ RR+HHCR CG IFC+ C + E+ Y +R C C + L ST S
Sbjct: 543 CEKEFSISRRKHHCRNCGHIFCNTCSSNEL--ALPSYPKPVRVCDSCHTLLLQRCSSTAS 600
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 67.4 bits (163), Expect = 1e-10
Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 47 SSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSA 106
SS + KE+ + Q E Q TS L Q V ++L +E
Sbjct: 437 SSLEKELKSEKEQRQALQRELQHEKD--TSSLLRMELQQVEGLKKELRELQDEKAELQKI 494
Query: 107 LDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYD 166
+ + +A G H ++ +++ + V + LK W+ D + C
Sbjct: 495 CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKG------------HAWLKDDEATHCRQ 542
Query: 167 CSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDS 226
C ++F+ RR+HHCR CG IFC+ C + E+ Y +R C C + L ST S
Sbjct: 543 CEKEFSISRRKHHCRNCGHIFCNTCSSNEL--ALPSYPKPVRVCDSCHTLLLQRCSSTAS 600
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 47 SSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSA 106
SS + KE+ + Q E Q TS L Q V ++L +E
Sbjct: 545 SSLEKELKSEKEQRQALQRELQHEKD--TSSLLRMELQQVEGLKKELRELQDEKAELQKI 602
Query: 107 LDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYD 166
+ + +A G H ++ +++ + V + LK W+ D + C
Sbjct: 603 CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKG------------HAWLKDDEATHCRQ 650
Query: 167 CSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDS 226
C ++F+ RR+HHCR CG IFC+ C + E+ Y +R C C + L ST S
Sbjct: 651 CEKEFSISRRKHHCRNCGHIFCNTCSSNEL--ALPSYPKPVRVCDSCHTLLLQRCSSTAS 708
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 67.0 bits (162), Expect = 2e-10
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
W+PDSQ C C +FT +RRHHCR CG++FC+ CC+ + +M + R C C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
Query: 215 KIALS 219
+ ++
Sbjct: 755 SVLMN 759
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 67.0 bits (162), Expect = 2e-10
Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
W+PDSQ C C +FT +RRHHCR CG++FC+ CC+ + +M + R C C
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
Query: 215 KIALS 219
+ ++
Sbjct: 755 SVLMN 759
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 66.2 bits (160), Expect = 3e-10
Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCR 214
W+PD CY C F R+HHCR CG +FCS CCNQ++P R C C
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSC- 1137
Query: 215 KIALSYAHSTDSN 227
S H T S+
Sbjct: 1138 ---YSSLHPTSSS 1147
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 65.5 bits (158), Expect = 5e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 123 RTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQY------WMPDSQCKECYDCSEKFTTFRR 176
RT L L R K+ + KS + +Q W+ D++ C DC +F+ R
Sbjct: 1132 RTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLGDTEANHCLDCKREFSWMVR 1191
Query: 177 RHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSN----SIGED 232
RHHCR+CG+IFC CCN + K G R C C + S DS+ S GE
Sbjct: 1192 RHHCRICGRIFCYYCCNNYVLSKHGGKKE--RCCRACFQKLSEGPGSPDSSGSGTSQGEP 1249
Query: 233 LNALSDSA 240
ALS ++
Sbjct: 1250 SPALSPAS 1257
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
[Homo sapiens]
Length = 406
Score = 64.7 bits (156), Expect = 9e-10
Identities = 61/209 (29%), Positives = 97/209 (46%), Gaps = 19/209 (9%)
Query: 1819 KFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARG-GKSGAAFYATEDDRFILK 1877
K YC + F +RE ++DF SL+ S+P +SGA F+ + D R+I+K
Sbjct: 91 KEYCPMV----FRNLRERF-GIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIK 145
Query: 1878 QMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVM 1937
+ +V + Y YI V+ T L + LG+YR+ N ++ ++V
Sbjct: 146 TITSEDVAEMHNILKKYHQYI---VECHGITLLPQFLGMYRL------NVDGVEIYVIVT 196
Query: 1938 ENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKA 1996
N+F R + + +DLKGS R +D K L D + + +YI ++K
Sbjct: 197 RNVFSHRLSVYRKYDLKGSTVAREA-SDKEKAKELPTLKDNDFIN--EGQKIYIDDNNKK 253
Query: 1997 VLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
V + D FL+ ++DYSLLVG D
Sbjct: 254 VFLEKLKKDVEFLAQLKLMDYSLLVGIHD 282
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 63.9 bits (154), Expect = 2e-09
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 16/222 (7%)
Query: 1805 INPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGA 1864
+ P V L D A + Y F +R+ ++D++ SL+ + P ++ G S
Sbjct: 65 VPPPVMLLPDDFKASSKIKEYCPQVFRNLRDRF-GIDDQDYLVSLTRNPPSESEG--SDG 121
Query: 1865 AFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNS 1924
F + D ++K++ ++ +Y YI V+ T L + LG+YR+ N
Sbjct: 122 RFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI---VKCHGNTLLPQFLGMYRVSVDNE 178
Query: 1925 QNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMV 1983
+ +LVM N+F R + + +DLKGSL +R +D K L D + L
Sbjct: 179 DSY------MLVMRNMFSHRLPVHRKYDLKGSLVSREA-SDKEKVKELPTLKDMDFLN-- 229
Query: 1984 RDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
++ +YI K + + D FL I+DYSLL+G D
Sbjct: 230 KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHD 271
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 62.0 bits (149), Expect = 6e-09
Identities = 52/185 (28%), Positives = 88/185 (47%), Gaps = 15/185 (8%)
Query: 1842 EEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNA 1901
++D++ SL+ + P ++ G S F + D ++K++ ++ +Y YI
Sbjct: 119 DQDYLVSLTRNPPSESEG--SDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI--- 173
Query: 1902 VQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRN 1960
V+ T L + LG+YR+ N + +LVM N+F R + + +DLKGSL +R
Sbjct: 174 VKCHGNTLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRKYDLKGSLVSRE 227
Query: 1961 VKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLL 2020
+D K L D + L ++ +YI K + + D FL I+DYSLL
Sbjct: 228 A-SDKEKVKELPTLKDMDFLN--KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLL 284
Query: 2021 VGRDD 2025
+G D
Sbjct: 285 LGIHD 289
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 62.0 bits (149), Expect = 6e-09
Identities = 52/185 (28%), Positives = 88/185 (47%), Gaps = 15/185 (8%)
Query: 1842 EEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNA 1901
++D++ SL+ + P ++ G S F + D ++K++ ++ +Y YI
Sbjct: 119 DQDYLVSLTRNPPSESEG--SDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI--- 173
Query: 1902 VQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRN 1960
V+ T L + LG+YR+ N + +LVM N+F R + + +DLKGSL +R
Sbjct: 174 VKCHGNTLLPQFLGMYRVSVDNEDSY------MLVMRNMFSHRLPVHRKYDLKGSLVSRE 227
Query: 1961 VKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLL 2020
+D K L D + L ++ +YI K + + D FL I+DYSLL
Sbjct: 228 A-SDKEKVKELPTLKDMDFLN--KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLL 284
Query: 2021 VGRDD 2025
+G D
Sbjct: 285 LGIHD 289
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 isoform
1 [Homo sapiens]
Length = 394
Score = 61.6 bits (148), Expect = 8e-09
Identities = 54/187 (28%), Positives = 95/187 (50%), Gaps = 17/187 (9%)
Query: 1838 LDSSEEDFIRSLSHSSPWQA--RGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYF 1895
L +EED+ +L P+ KS A+F+ + D RF LK R EVQ+ L P Y
Sbjct: 112 LGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYV 171
Query: 1896 NYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFY-GRKMAQVFDLKG 1954
++ Q+ + LA++LGV+ + + + KK +VM+++FY ++++ +D+KG
Sbjct: 172 QHL----QRHPHSLLARLLGVHSL-----RVDRGKKTYFIVMQSVFYPAGRISERYDIKG 222
Query: 1955 SLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLI 2014
+R V D E +VL+ ++L + + + LR + D+ FL +
Sbjct: 223 CEVSRWV--DPAPEGSPLVLVLKDL--NFQGKTINLGPQRSWFLR-QMELDTTFLRELNV 277
Query: 2015 IDYSLLV 2021
+DYSLL+
Sbjct: 278 LDYSLLI 284
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 60.8 bits (146), Expect = 1e-08
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIP 197
W+PD CY+C +F +RRHHCR CG +FC+ CC+ ++P
Sbjct: 1111 WVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP 1153
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 60.8 bits (146), Expect = 1e-08
Identities = 25/76 (32%), Positives = 39/76 (51%)
Query: 140 EIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGK 199
+I G +D+ YW+PD + C++C ++F+ +HHCR CGQ FC C +
Sbjct: 282 DIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVP 341
Query: 200 FMGYTGDLRACTYCRK 215
G+ +R C C K
Sbjct: 342 SRGWDHPVRVCFNCNK 357
Score = 51.6 bits (122), Expect = 8e-06
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 154 YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGY-TGDLRACTY 212
YW P+SQ C C+ F +HHCR CG+ FC C ++ P G+ +R C
Sbjct: 179 YWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDN 238
Query: 213 C 213
C
Sbjct: 239 C 239
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 60.8 bits (146), Expect = 1e-08
Identities = 25/76 (32%), Positives = 39/76 (51%)
Query: 140 EIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGK 199
+I G +D+ YW+PD + C++C ++F+ +HHCR CGQ FC C +
Sbjct: 697 DIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVP 756
Query: 200 FMGYTGDLRACTYCRK 215
G+ +R C C K
Sbjct: 757 SRGWDHPVRVCFNCNK 772
Score = 51.6 bits (122), Expect = 8e-06
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 154 YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGY-TGDLRACTY 212
YW P+SQ C C+ F +HHCR CG+ FC C ++ P G+ +R C
Sbjct: 594 YWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDN 653
Query: 213 C 213
C
Sbjct: 654 C 654
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 59.3 bits (142), Expect = 4e-08
Identities = 74/321 (23%), Positives = 137/321 (42%), Gaps = 47/321 (14%)
Query: 554 GQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANH 613
G+ L +D +I E L R + E + L E+L E K+ ++L
Sbjct: 100 GELLKQADLYISEGLHPRIIAEGFEAAKIKAL-------EVLEEVKVTKEMKRKILL--- 149
Query: 614 NHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGG 673
+ LQ +H++ D++ +V V VR D+ + + + +K G
Sbjct: 150 DVARTSLQTKVHAELA-----DVLTEVVVDSVLAVRRP--GYPIDLFMVEIMEMKHKLGT 202
Query: 674 KKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTC---------I 724
D+ ++ G V H M +++ IL+ S+EY E+T+
Sbjct: 203 ---DTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEY---EKTEVNSGFFYKTAEEK 256
Query: 725 DPIVLQEREFLKNYVQRIVDVRPTL---------VLVEKTVSRIAQDMLLEHGITLVINV 775
+ +V ER+F+++ VQ+I+D++ + V+ +K + + D L +HGI +
Sbjct: 257 EKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRA 316
Query: 776 KSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHL 835
K + +ER+S G V S + LT LG H + + L E+ F E C
Sbjct: 317 KRRNMERLSLACGGMAVNSFED-LTVDCLG--HAGLVYEYTLGEEK---FTFIEECVNPC 370
Query: 836 GCTIKLRGGSDYELARVKEIL 856
T+ ++G + + L +VK+ +
Sbjct: 371 SVTLLVKGPNKHTLTQVKDAI 391
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 58.5 bits (140), Expect = 7e-08
Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 155 WMPDSQCKECYDCSEKFTTFRRRHHCR---------LCGQIFCSRCCNQEIPGKFMGYTG 205
W+PD CY C F R+HHCR CG +FCS CCNQ++P
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFE 1138
Query: 206 DLRACTYCRKIALSYAHSTDSN 227
R C C S H T S+
Sbjct: 1139 PSRVCKSC----YSSLHPTSSS 1156
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 58.5 bits (140), Expect = 7e-08
Identities = 38/166 (22%), Positives = 70/166 (42%), Gaps = 23/166 (13%)
Query: 78 QLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGHDPRTAVQLRSLSTVLKR 137
QL ++ +++ L E+LQ+ AL R + + L+ + LK+
Sbjct: 476 QLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRNETQQIISLK-KEFLNLQDENQQLKK 534
Query: 138 L------------KEIMEGKSQDSDLKQ--------YWMPDSQCKECYDCSEKFTTFRRR 177
+ ++ E K + D+K+ W+ D + C C ++F+ +R+
Sbjct: 535 IYHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRK 594
Query: 178 HHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHS 223
HHCR CG+IFC+ C + E+P +R C C + + S
Sbjct: 595 HHCRNCGEIFCNACSDNELP--LPSSPKPVRVCDSCHALLIQRCSS 638
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 57.0 bits (136), Expect = 2e-07
Identities = 56/210 (26%), Positives = 92/210 (43%), Gaps = 15/210 (7%)
Query: 1818 AKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARG-GKSGAAFYATEDDRFIL 1876
++F + Y F +RE ++D+ S++ S+P + G+ G F T D RF++
Sbjct: 91 SRFKFKEYCPMVFRNLRERF-GIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVI 149
Query: 1877 KQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLV 1936
K + +V + Y +I V+ T L + LG+YR+ + ++V
Sbjct: 150 KTVSSEDVAEMHNILKKYHQFI---VECHGNTLLPQFLGMYRLTVDGVETY------MVV 200
Query: 1937 MENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSK 1995
N+F R + + +DLKGS R +D K D + L L++ SK
Sbjct: 201 TRNVFSHRLTVHRKYDLKGSTVAREA-SDKEKAKDLPTFKDNDFLN--EGQKLHVGEESK 257
Query: 1996 AVLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
+ D FL+ I+DYSLLVG D
Sbjct: 258 KNFLEKLKRDVEFLAQLKIMDYSLLVGIHD 287
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,271,410
Number of Sequences: 37866
Number of extensions: 4059346
Number of successful extensions: 15177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 14566
Number of HSP's gapped (non-prelim): 713
length of query: 2098
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1980
effective length of database: 13,779,330
effective search space: 27283073400
effective search space used: 27283073400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.