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Search of human proteins with 121114306
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|121114306 neurogenic differentiation 1 [Homo sapiens]
(356 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|121114306 neurogenic differentiation 1 [Homo sapiens] 736 0.0
gi|153792190 neurogenic differentiation 4 [Homo sapiens] 354 6e-98
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 324 6e-89
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 310 2e-84
gi|38455396 neurogenin 1 [Homo sapiens] 90 4e-18
gi|31077092 neurogenin 2 [Homo sapiens] 86 5e-17
gi|68989258 neurogenin 3 [Homo sapiens] 82 1e-15
gi|4885075 atonal homolog 1 [Homo sapiens] 76 5e-14
gi|21553337 atonal homolog 7 [Homo sapiens] 72 1e-12
gi|23097242 nephew of atonal 3 [Homo sapiens] 70 3e-12
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 69 5e-12
gi|226498192 atonal homolog 8 [Homo sapiens] 68 1e-11
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 65 1e-10
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 62 1e-09
gi|38202237 transcription factor 21 [Homo sapiens] 60 2e-09
gi|38202239 transcription factor 21 [Homo sapiens] 60 2e-09
gi|17981708 twist homolog 2 [Homo sapiens] 60 4e-09
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 59 5e-09
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 58 1e-08
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 57 3e-08
gi|148922889 scleraxis homolog B [Homo sapiens] 56 4e-08
gi|186972126 scleraxis homolog A [Homo sapiens] 56 4e-08
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 54 3e-07
gi|157739932 mesogenin 1 [Homo sapiens] 53 4e-07
gi|4507741 twist [Homo sapiens] 53 5e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 53 5e-07
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 52 6e-07
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 51 1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 51 1e-06
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 51 2e-06
>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
Length = 356
Score = 736 bits (1900), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 1 MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEE 60
MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEE
Sbjct: 1 MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEE 60
Query: 61 DEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA 120
DEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA
Sbjct: 61 DEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA 120
Query: 121 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT 180
LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT
Sbjct: 121 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT 180
Query: 181 TNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVF 240
TNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVF
Sbjct: 181 TNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVF 240
Query: 241 HVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNYAFT 300
HVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNYAFT
Sbjct: 241 HVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNYAFT 300
Query: 301 MHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERVMSAQLNAIFHD 356
MHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERVMSAQLNAIFHD
Sbjct: 301 MHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERVMSAQLNAIFHD 356
>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
Length = 331
Score = 354 bits (909), Expect = 6e-98
Identities = 188/357 (52%), Positives = 249/357 (69%), Gaps = 31/357 (8%)
Query: 1 MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDD---LEAMNAEEDSLRNGG 57
M+K++ +S MGE PSW D+ L SQ+E E + + L ++ E DS+
Sbjct: 1 MSKTFVKSKEMGELV--NTPSWMDKGLGSQNEVKEEESRPGTYGMLSSLTEEHDSI---- 54
Query: 58 EEEDEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGL 117
EEEEEEE+D +KPKRRGPKKKKMTKARLERF+ RR+KANARER RMHGL
Sbjct: 55 -----------EEEEEEEEDGEKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGL 103
Query: 118 NAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLS 177
N ALDNLR+V+PCYSKTQKLSKIETLRLA+NYIWALSE+L +G++P+ FV+ LCKGLS
Sbjct: 104 NDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTPEGKGFVEMLCKGLS 163
Query: 178 QPTTNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSS 237
QPT+NLVAGCLQL P++ L E+++D P ++ VH ++YQSPGLPSPPYG M+ +
Sbjct: 164 QPTSNLVAGCLQLGPQSVLLEKHEDKS---PICDSAISVHNFNYQSPGLPSPPYGHME-T 219
Query: 238 HVFHVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNY 297
H+ H+K P + + E F S L DC++P ++GPL+PPLSI+GNFS K + S + EK+Y
Sbjct: 220 HLLHLK--PQVFKSLGESSFGSHLPDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSY 277
Query: 298 AFTMHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERVMSAQLNAIF 354
+F HYP+++L+ H + F PR ++PID MS+DS+ HH + QLN +F
Sbjct: 278 SFMPHYPSSSLSSGHVHSTPFQ-AGTPRYDVPID--MSYDSYPHHG--IGTQLNTVF 329
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 324 bits (831), Expect = 6e-89
Identities = 179/326 (54%), Positives = 219/326 (67%), Gaps = 15/326 (4%)
Query: 40 EDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERF 99
E+ EA AE ++ GE E+E+ EEEEE +E + ++PK+RGPKK+KMTKARLER
Sbjct: 63 EEGTEATLAE---VKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERS 119
Query: 100 KLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS 159
KLRR KANARERNRMH LNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS
Sbjct: 120 KLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS 179
Query: 160 GKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPY 219
GK PDLVS+VQTLCKGLSQPTTNLVAGCLQLN R FL EQ D + F +HPY
Sbjct: 180 GKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPY 239
Query: 220 SY---QSPGLPSPPYGTMDSSHVFHVKPPPHAYSAALEPFFES-----PLTDCTSPSFDG 271
Y + G G + ++ H Y AA E + + D S ++G
Sbjct: 240 PYPCSRLAGAQCQAAGGLGGGAAHALR--THGYCAAYETLYAAAGGGGASPDYNSSEYEG 297
Query: 272 PLSPPLSINGNFSFKHEPSAEFEKNYAFTMHYPAATLAGAQSHGSIFSGTAAPRCEIPID 331
PLSPPL +NGNFS K + S + EK+Y ++MHY A + HG +F G++A R + +
Sbjct: 298 PLSPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVF-GSSAVRGGVHSE 356
Query: 332 NIMSFDSHSHHER-VMSAQLNAIFHD 356
N++S+D H HH+R M +LNA FH+
Sbjct: 357 NLLSYDMHLHHDRGPMYEELNAFFHN 382
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 310 bits (793), Expect = 2e-84
Identities = 179/359 (49%), Positives = 232/359 (64%), Gaps = 26/359 (7%)
Query: 1 MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEE 60
+T + ES +M P+ Q ++ EC +++ + K E + + S++ EE
Sbjct: 2 LTLPFDESVVM--PESQMCRKFSREC----EDQKQIKKPESFSKQIVLRGKSIKRAPGEE 55
Query: 61 DEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA 120
E E EEEE+ EEED++ P+RRG +KKK TK RLER K RR +ANARERNRMHGLN A
Sbjct: 56 TEKE--EEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDA 113
Query: 121 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT 180
LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR GK PDL++FVQ LCKGLSQPT
Sbjct: 114 LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPT 173
Query: 181 TNLVAGCLQLNPRTFLPEQNQDMPPHLPTASASFPVHPYSYQSPGLPSPP-YGTMDSSHV 239
TNLVAGCLQLN R+FL Q + H + ++F +P Y SP L +PP +GT+D+S
Sbjct: 174 TNLVAGCLQLNARSFLMGQGGEAAHHTRSPYSTF--YP-PYHSPELTTPPGHGTLDNSK- 229
Query: 240 FHVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLS-PPLSINGNFSFKHEPSAEFEKNYA 298
P+ Y +A E F+ES +C SP F+GPLS PP++ NG FS K E + ++ KNY
Sbjct: 230 ---SMKPYNYCSAYESFYESTSPECASPQFEGPLSPPPINYNGIFSLKQEETLDYGKNYN 286
Query: 299 FTMHYPAATLAGAQSHGSIFSGTAAPRCEIPIDNIMSFDSHSHHERV-MSAQLNAIFHD 356
+ MHY A G G++F +P D+ +D H + + M +LNA+FH+
Sbjct: 287 YGMHYCAVPPRGPLGQGAMF--------RLPTDSHFPYDLHLRSQSLTMQDELNAVFHN 337
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 89.7 bits (221), Expect = 4e-18
Identities = 47/85 (55%), Positives = 61/85 (71%), Gaps = 1/85 (1%)
Query: 75 EDDDQKPKRRGPKKKKMTKARLERFKL-RRMKANARERNRMHGLNAALDNLRKVVPCYSK 133
+DD+Q+ +RR + + ++A L + RR+KAN RERNRMH LNAALD LR V+P +
Sbjct: 65 QDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPD 124
Query: 134 TQKLSKIETLRLAKNYIWALSEILR 158
KL+KIETLR A NYIWAL+E LR
Sbjct: 125 DTKLTKIETLRFAYNYIWALAETLR 149
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 85.9 bits (211), Expect = 5e-17
Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 2/85 (2%)
Query: 76 DDDQKPKR-RGPKKKKMTKARLERFK-LRRMKANARERNRMHGLNAALDNLRKVVPCYSK 133
D ++P R R + T ++R K RR+KAN RERNRMH LNAALD LR+V+P + +
Sbjct: 85 DCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPE 144
Query: 134 TQKLSKIETLRLAKNYIWALSEILR 158
KL+KIETLR A NYIWAL+E LR
Sbjct: 145 DAKLTKIETLRFAHNYIWALTETLR 169
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 81.6 bits (200), Expect = 1e-15
Identities = 42/79 (53%), Positives = 54/79 (68%)
Query: 80 KPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSK 139
+ +R G + K A ++ + RR KAN RERNRMH LN+ALD LR V+P + KL+K
Sbjct: 62 RARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTK 121
Query: 140 IETLRLAKNYIWALSEILR 158
IETLR A NYIWAL++ LR
Sbjct: 122 IETLRFAHNYIWALTQTLR 140
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 75.9 bits (185), Expect = 5e-14
Identities = 39/78 (50%), Positives = 55/78 (70%), Gaps = 4/78 (5%)
Query: 82 KRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIE 141
++R P K++ + K RR+ ANARER RMHGLN A D LR V+P ++ +KLSK E
Sbjct: 144 RQRAPSSKQVNGVQ----KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYE 199
Query: 142 TLRLAKNYIWALSEILRS 159
TL++A+ YI ALSE+L++
Sbjct: 200 TLQMAQIYINALSELLQT 217
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 71.6 bits (174), Expect = 1e-12
Identities = 37/63 (58%), Positives = 46/63 (73%)
Query: 95 RLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALS 154
RLE RR+ ANARER RM GLN A D LR+VVP + + +KLSK ETL++A +YI AL+
Sbjct: 34 RLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALT 93
Query: 155 EIL 157
IL
Sbjct: 94 RIL 96
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 70.1 bits (170), Expect = 3e-12
Identities = 44/103 (42%), Positives = 62/103 (60%), Gaps = 7/103 (6%)
Query: 58 EEEDEDEDLEEEEEEEEEDDDQKPKRRG-PKKKKMTKARLERFKLRRMKANARERNRMHG 116
EEE+ + D + EEEEEE+ + G PK+K++ +R AN RER RM
Sbjct: 63 EEEECEVDQGDGEEEEEEERGRGVSLLGRPKRKRVITYA------QRQAANIRERKRMFN 116
Query: 117 LNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS 159
LN A D LR+ VP ++ ++LS+IETLRLA YI ++E+L S
Sbjct: 117 LNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLES 159
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 69.3 bits (168), Expect = 5e-12
Identities = 47/118 (39%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
Query: 64 EDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDN 123
E E+ +E++ +Q+ +RRGP + R + R+ NARER RMH LN ALD
Sbjct: 63 ESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDG 122
Query: 124 LRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQP 179
LR V+P +KLSKI TL LAKNYI ++ L + LV+F+ +GL+ P
Sbjct: 123 LRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRR--LVAFLNQ-GQGLAAP 177
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 68.2 bits (165), Expect = 1e-11
Identities = 37/90 (41%), Positives = 53/90 (58%)
Query: 75 EDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKT 134
+D P++R + + + RR+ ANARER R+H ++AA + LRK VPCYS
Sbjct: 204 QDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYG 263
Query: 135 QKLSKIETLRLAKNYIWALSEILRSGKSPD 164
QKLSK+ LR+A NYI +L+ + S D
Sbjct: 264 QKLSKLAILRIACNYILSLARLADLDYSAD 293
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/171 (35%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 88 KKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCY--SKTQKLSKIETLRL 145
KK+MT+ L++ R+K N+RER RMH LN A+D LR+V+P +KLSKI TL L
Sbjct: 98 KKQMTEPELQQL---RLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154
Query: 146 AKNYIWALSEILRSGKSPDLVS---------FVQTLCKGL--SQPTTNLVAGCLQLNPRT 194
A+NYI L+ L K LVS F + C GL S P A
Sbjct: 155 ARNYILMLTNSLEEMKR--LVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAA 212
Query: 195 FLPEQNQDMPP----HLPTASASFPVHPYSYQSPGLPS-----PPYGTMDS 236
P + + P A+A+ V S GLPS PP+G + S
Sbjct: 213 HHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKS 263
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 61.6 bits (148), Expect = 1e-09
Identities = 46/127 (36%), Positives = 62/127 (48%), Gaps = 6/127 (4%)
Query: 42 DLEAMNAE---EDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGPKKKKMTKARLER 98
D EA E + SL N G E + + + +R GP R +
Sbjct: 16 DTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPG---GRRDS 72
Query: 99 FKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 158
RR+++N RER RMH LN A LR+V+P +KLSKIETL LAKNYI +L+ +
Sbjct: 73 SIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATIL 132
Query: 159 SGKSPDL 165
+ S L
Sbjct: 133 TMSSSRL 139
>gi|38202237 transcription factor 21 [Homo sapiens]
Length = 179
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Query: 27 LSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGP 86
LS ++ E + E D M++ ++ + + E +E + E ++ K ++
Sbjct: 6 LSDVEDLQEVEMLECDGLKMDSNKEFVTSN-ESTEESSNCENGSPQKGRGGLGKRRKAPT 64
Query: 87 KKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLA 146
KK ++ E +++R ANARER RM L+ A L+ +P KLSK++TLRLA
Sbjct: 65 KKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLA 124
Query: 147 KNYIWALSEILRSGK 161
+YI L +IL + K
Sbjct: 125 SSYIAHLRQILANDK 139
>gi|38202239 transcription factor 21 [Homo sapiens]
Length = 179
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Query: 27 LSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGP 86
LS ++ E + E D M++ ++ + + E +E + E ++ K ++
Sbjct: 6 LSDVEDLQEVEMLECDGLKMDSNKEFVTSN-ESTEESSNCENGSPQKGRGGLGKRRKAPT 64
Query: 87 KKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLA 146
KK ++ E +++R ANARER RM L+ A L+ +P KLSK++TLRLA
Sbjct: 65 KKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLA 124
Query: 147 KNYIWALSEILRSGK 161
+YI L +IL + K
Sbjct: 125 SSYIAHLRQILANDK 139
>gi|17981708 twist homolog 2 [Homo sapiens]
Length = 160
Score = 59.7 bits (143), Expect = 4e-09
Identities = 36/89 (40%), Positives = 51/89 (57%), Gaps = 2/89 (2%)
Query: 71 EEEEEDDDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPC 130
++ ED P +RG KK + E + +R+ AN RER R LN A LRK++P
Sbjct: 37 KKSSEDGSPTPGKRG-KKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPT 95
Query: 131 YSKTQKLSKIETLRLAKNYIWALSEILRS 159
+ KLSKI+TL+LA YI L ++L+S
Sbjct: 96 L-PSDKLSKIQTLKLAARYIDFLYQVLQS 123
>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
Length = 272
Score = 59.3 bits (142), Expect = 5e-09
Identities = 38/84 (45%), Positives = 47/84 (55%), Gaps = 4/84 (4%)
Query: 82 KRRGPKKKKMTKARLERFKLR--RMKANARERNRMHGLNAALDNLRKVVPCY--SKTQKL 137
K G K K +L L+ R+K N RER RMH LN A+D LR+V+P +KL
Sbjct: 62 KAAGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKL 121
Query: 138 SKIETLRLAKNYIWALSEILRSGK 161
SKI TL LA+NYI L+ L K
Sbjct: 122 SKIATLLLARNYILMLTSSLEEMK 145
>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
sapiens]
Length = 199
Score = 57.8 bits (138), Expect = 1e-08
Identities = 31/63 (49%), Positives = 40/63 (63%)
Query: 102 RRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGK 161
+R ANARER+R +N A LR ++P +KLSKIETLRLA +YI L+ +L G
Sbjct: 73 QRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGD 132
Query: 162 SPD 164
S D
Sbjct: 133 SAD 135
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 57.0 bits (136), Expect = 3e-08
Identities = 33/60 (55%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
Query: 100 KLRRMKANARERNRMHGLNAALDNLRKVVPC--YSKTQKLSKIETLRLAKNYIWALSEIL 157
K R+ NARER RMH LN ALD LR V+P +KLSKI TL LAKNYI ++ L
Sbjct: 241 KALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQAL 300
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 56.2 bits (134), Expect = 4e-08
Identities = 29/61 (47%), Positives = 41/61 (67%)
Query: 102 RRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGK 161
+R ANARER+R + +N A LR ++P +KLSKIETLRLA +YI L +L +G+
Sbjct: 76 QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135
Query: 162 S 162
+
Sbjct: 136 A 136
>gi|186972126 scleraxis homolog A [Homo sapiens]
Length = 201
Score = 56.2 bits (134), Expect = 4e-08
Identities = 29/61 (47%), Positives = 41/61 (67%)
Query: 102 RRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGK 161
+R ANARER+R + +N A LR ++P +KLSKIETLRLA +YI L +L +G+
Sbjct: 76 QRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135
Query: 162 S 162
+
Sbjct: 136 A 136
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 53.5 bits (127), Expect = 3e-07
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Query: 87 KKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLA 146
++++ ++ E +LR+ AN RER RM +N A + LR +P ++LSK++TLRLA
Sbjct: 150 RRRRRVRSEAELQQLRQA-ANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLA 208
Query: 147 KNYIWALSEILRS 159
YI LSE++++
Sbjct: 209 IGYINFLSELVQA 221
>gi|157739932 mesogenin 1 [Homo sapiens]
Length = 193
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/81 (43%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
Query: 85 GPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVP-CYSKT-QKLSKIET 142
GPK +K TK R+ RR KA+ RE+ RM L AL LR +P YS+ Q L+KI+T
Sbjct: 110 GPKAQKGTKVRMS--VQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQT 167
Query: 143 LRLAKNYIWALSEILRSGKSP 163
L+ YI L+++L G+ P
Sbjct: 168 LKYTIKYIGELTDLLNRGREP 188
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 52.8 bits (125), Expect = 5e-07
Identities = 29/63 (46%), Positives = 40/63 (63%), Gaps = 1/63 (1%)
Query: 97 ERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEI 156
E + +R+ AN RER R LN A LRK++P + KLSKI+TL+LA YI L ++
Sbjct: 104 EELQTQRVMANVRERQRTQSLNEAFAALRKIIPTL-PSDKLSKIQTLKLAARYIDFLYQV 162
Query: 157 LRS 159
L+S
Sbjct: 163 LQS 165
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 7/79 (8%)
Query: 12 GEPQPQGPPSWTDECL-----SSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDL 66
G P GPP+ ++ SS +EE E +++E++ E EE+ EEEDE+E
Sbjct: 864 GTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE--EEEDEEEYF 921
Query: 67 EEEEEEEEEDDDQKPKRRG 85
EEEEEEEEE +++ + G
Sbjct: 922 EEEEEEEEEFEEEFEEEEG 940
Score = 40.0 bits (92), Expect = 0.003
Identities = 20/48 (41%), Positives = 30/48 (62%)
Query: 30 QDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDD 77
+DEE +++E++ E E + EEE+E+ED EEEEE EE +D
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/56 (39%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Query: 24 DECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGE-EEDEDEDLEEEEEEEEEDDD 78
+E ++E+ E +E++ E EE+ GE EE+E+E+ EEEEEE EE +D
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Score = 34.3 bits (77), Expect = 0.18
Identities = 18/43 (41%), Positives = 25/43 (58%)
Query: 33 EHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEE 75
E E +++E+ E EE L EEEDE+E+ E EE E+ E
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 29.3 bits (64), Expect = 5.6
Identities = 15/47 (31%), Positives = 26/47 (55%)
Query: 24 DECLSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEE 70
+E ++EE E ++E + E EE+ EEE+E E++E+ E
Sbjct: 918 EEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 28.9 bits (63), Expect = 7.4
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 8/44 (18%)
Query: 30 QDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEE 73
++ E E +++E +LE EED E+E+E+LEE E+ E
Sbjct: 929 EEFEEEFEEEEGELEEEEEEED--------EEEEEELEEVEDLE 964
>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
Length = 271
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 7/72 (9%)
Query: 94 ARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKT-------QKLSKIETLRLA 146
A+ E+ + R K N+RER RM LN A+D LR+V+ YS +KLSKI TL LA
Sbjct: 98 AKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLA 157
Query: 147 KNYIWALSEILR 158
+NYI L L+
Sbjct: 158 RNYILLLGSSLQ 169
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/48 (47%), Positives = 36/48 (75%), Gaps = 1/48 (2%)
Query: 40 EDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGPK 87
E++ E +E+ GGEEE+E+E+ EEEEEEEEE+++++P R GP+
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQP-RAGPQ 154
Score = 42.7 bits (99), Expect = 5e-04
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
Query: 31 DEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRG 85
+EE E ++++++++ EE+ EEE+E+E+ EEEEEEEEE P+ G
Sbjct: 108 EEETEREEEDEEIQEEGGEEEE-----EEEEEEEEEEEEEEEEEEQPRAGPQGSG 157
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 51.2 bits (121), Expect = 1e-06
Identities = 23/55 (41%), Positives = 38/55 (69%)
Query: 27 LSSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKP 81
LS ++E+ E +++E++ E EE+ EEE+E+E+ EEEEEEEEE+++ P
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 50.1 bits (118), Expect = 3e-06
Identities = 22/53 (41%), Positives = 35/53 (66%)
Query: 34 HEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGP 86
HE + +E++ E EED EEE+E+E+ EEEEEEEEE+++++ + P
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 13/71 (18%)
Query: 30 QDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDD----------- 78
++EE E +++E+D E EE+ EEE+E+E+ EEEEEEEE D
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTS 321
Query: 79 --QKPKRRGPK 87
+ P+ RGP+
Sbjct: 322 AQKAPELRGPE 332
Score = 43.9 bits (102), Expect = 2e-04
Identities = 20/63 (31%), Positives = 38/63 (60%)
Query: 28 SSQDEEHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGPK 87
S +D E K+ + + E++ EEE+EDE+ EEEEEEEEE+++++ + +
Sbjct: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Query: 88 KKK 90
+++
Sbjct: 299 EEE 301
Score = 40.0 bits (92), Expect = 0.003
Identities = 20/69 (28%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 24 DECLSSQDE--EHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKP 81
D C S ++ E+ K++ L +E+ EEE+++E+ EEEEEEEEE+++++
Sbjct: 234 DLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293
Query: 82 KRRGPKKKK 90
+ ++++
Sbjct: 294 EEEEEEEEE 302
Score = 39.3 bits (90), Expect = 0.005
Identities = 19/58 (32%), Positives = 34/58 (58%)
Query: 33 EHEADKKEDDLEAMNAEEDSLRNGGEEEDEDEDLEEEEEEEEEDDDQKPKRRGPKKKK 90
E D LE +EE S + G +E+++ EEEEEEEEE+D+++ + ++++
Sbjct: 230 ERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 287
>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 203
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/71 (45%), Positives = 43/71 (60%)
Query: 93 KARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWA 152
+AR R K RRM AN RER R+ N A + LR+ + ++LSKI TLR A + I A
Sbjct: 57 RARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAA 116
Query: 153 LSEILRSGKSP 163
LS +LR+ +P
Sbjct: 117 LSLVLRASPAP 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,901,989
Number of Sequences: 37866
Number of extensions: 985063
Number of successful extensions: 32054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 938
Number of HSP's successfully gapped in prelim test: 589
Number of HSP's that attempted gapping in prelim test: 9642
Number of HSP's gapped (non-prelim): 10857
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.