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Search of human proteins with 24497589
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497589 aristaless related homeobox [Homo sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497589 aristaless related homeobox [Homo sapiens] 1117 0.0
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 139 7e-33
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 137 3e-32
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 135 1e-31
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 129 7e-30
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 126 6e-29
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 123 5e-28
gi|14149760 orthopedia homeobox [Homo sapiens] 123 5e-28
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 122 1e-27
gi|46249382 paired-like homeobox 2a [Homo sapiens] 119 1e-26
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 118 2e-26
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 114 2e-25
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 114 2e-25
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 114 2e-25
gi|12707580 paired-like homeobox 2b [Homo sapiens] 112 7e-25
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 111 2e-24
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 111 2e-24
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 111 2e-24
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 111 2e-24
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 111 2e-24
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 111 2e-24
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 111 2e-24
gi|7706659 paired related homeobox 2 [Homo sapiens] 109 6e-24
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 108 1e-23
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 108 2e-23
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 108 2e-23
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 107 3e-23
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 107 3e-23
gi|34365783 visual system homeobox 2 [Homo sapiens] 106 5e-23
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 105 8e-23
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 1117 bits (2888), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP 60
MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP
Sbjct: 1 MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP 60
Query: 61 EKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAG 120
EKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAG
Sbjct: 61 EKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAG 120
Query: 121 PRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGA 180
PRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGA
Sbjct: 121 PRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGA 180
Query: 181 PFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEE 240
PFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEE
Sbjct: 181 PFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEE 240
Query: 241 EELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPE 300
EELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPE
Sbjct: 241 EELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPE 300
Query: 301 DAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREE 360
DAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREE
Sbjct: 301 DAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREE 360
Query: 361 LAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFP 420
LAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFP
Sbjct: 361 LAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFP 420
Query: 421 PHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPA 480
PHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPA
Sbjct: 421 PHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPA 480
Query: 481 FGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAK 540
FGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAK
Sbjct: 481 FGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAK 540
Query: 541 EHAAQLTQLNILPGTSTGKEVC 562
EHAAQLTQLNILPGTSTGKEVC
Sbjct: 541 EHAAQLTQLNILPGTSTGKEVC 562
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 139 bits (350), Expect = 7e-33
Identities = 110/271 (40%), Positives = 140/271 (51%), Gaps = 40/271 (14%)
Query: 282 VATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLE 341
V + LS KE + P+D D S A S+S +G K+RR RTTFTSYQLE
Sbjct: 173 VGMDSSYLSVKEAGVKGPQDRASSD-LPSPLEKADSESNKG----KKRRNRTTFTSYQLE 227
Query: 342 ELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAG----AQTHPPG 397
ELE+ FQKTHYPDV+ RE+LAMR DLTEARVQVWFQNRRAKWRKRE+ G +TH
Sbjct: 228 ELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTH--- 284
Query: 398 LPFPGPLSATHPLSPYLDASPFPP-HHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPS 456
S + L A + +P+ AA+ A P P P A + P
Sbjct: 285 ------FSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVP---ACMSPH 335
Query: 457 GAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGA 516
P G GA+ +S A + T + S AA+L +P + G +G
Sbjct: 336 AHPPG----SGASSVTDFLSVSGAGSHVGQT--HMGSLFGAASL----SPGLNGYELNG- 384
Query: 517 LADPATAAADRRASSIAALRLKAKEHAAQLT 547
DR+ SSIAALR+KAKEH+A ++
Sbjct: 385 -------EPDRKTSSIAALRMKAKEHSAAIS 408
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 137 bits (344), Expect = 3e-32
Identities = 100/245 (40%), Positives = 124/245 (50%), Gaps = 34/245 (13%)
Query: 315 AGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQV 374
+ D ++G L+RKQRR RTTFT QLE LE F +THYPDVFTREELAM+++LTEARVQV
Sbjct: 25 SSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQV 84
Query: 375 WFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAA 434
WFQNRRAKWRK E+ GA PG A P+ A PP ++S
Sbjct: 85 WFQNRRAKWRKTER-GASDQEPG--------AKEPM-----AEVTPPPVRNINS------ 124
Query: 435 AAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVF-RHPAFISPAFGRLFSTMAPLTS 493
PPPG + A L LG V P F S G L +T +
Sbjct: 125 -----------PPPGDQARSKKEA-LEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQA 172
Query: 494 ASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHA-AQLTQLNIL 552
S A+L P + G P R +S+A LR+KA+EH+ A L N+L
Sbjct: 173 LSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLL 232
Query: 553 PGTST 557
P TS+
Sbjct: 233 PSTSS 237
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 135 bits (339), Expect = 1e-31
Identities = 93/238 (39%), Positives = 125/238 (52%), Gaps = 40/238 (16%)
Query: 316 GSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVW 375
G + + K+RR+RTTFTS QLEELE+ FQKTHYPDV+ RE+LA+R +LTEARVQVW
Sbjct: 120 GDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVW 179
Query: 376 FQNRRAKWRKREKAG----AQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWT 431
FQNRRAKWRKRE+ G A++H +AT+ +S P +P + +
Sbjct: 180 FQNRRAKWRKRERYGQIQQAKSH---------FAATYDIS----VLPRTDSYPQIQNNLW 226
Query: 432 AAAAAAAAAFPS--LPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMA 489
A A+ + S LP S P S +P S++ G + H S F T +
Sbjct: 227 AGNASGGSVVTSCMLPRDTSSCMTPYSHSPRTDSSYTGFS--NHQNQFSHVPLNNFFTDS 284
Query: 490 PLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLT 547
LT A+ A +P +RR+SSIA LR+KAKEH A ++
Sbjct: 285 LLTGATNGHAFETKP-------------------EFERRSSSIAVLRMKAKEHTANIS 323
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 129 bits (324), Expect = 7e-30
Identities = 114/299 (38%), Positives = 131/299 (43%), Gaps = 63/299 (21%)
Query: 262 EPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEE 321
EP P A A E GE P L + P E K SEE
Sbjct: 82 EPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEAKL------------SEE 129
Query: 322 GLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRA 381
K+K RR RTTFT+YQL ELERAF+K+HYPDV++REELA +++L E RVQVWFQNRRA
Sbjct: 130 EQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRA 189
Query: 382 KWRKREKAGAQT----HPPGLPFP-GPLSATHPLSPYLDASPFPPHHPA---------LD 427
KWR++EK + P L F P SAT LSP L A P PA L
Sbjct: 190 KWRRQEKLEVSSMKLQDSPLLSFSRSPPSAT--LSP-LGAGPGSGGGPAGGALPLESWLG 246
Query: 428 SAWTAAAAAAAAAFPSLPPP----PGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGR 483
A A + P PP P S + PP P FL SP G
Sbjct: 247 PPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPP-----FLN----------SPPLGP 291
Query: 484 LFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEH 542
+AP + P E AD R SSIAALRLKAKEH
Sbjct: 292 GLQPLAPPPPSYPCGPGFGDKFPLDE---------------ADPRNSSIAALRLKAKEH 335
Score = 29.6 bits (65), Expect = 7.7
Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 16/89 (17%)
Query: 43 LLGAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAA 102
LL ++S P+ S G P + P E+ L P PGGG
Sbjct: 209 LLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPL-------PGGG-------- 253
Query: 103 AAAAAAAAAAAAATATAGPRGEAPPPPPP 131
A A + A + P PPPPPP
Sbjct: 254 -ATALQSLPGFGPPAQSLPASYTPPPPPP 281
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 126 bits (316), Expect = 6e-29
Identities = 96/260 (36%), Positives = 125/260 (48%), Gaps = 38/260 (14%)
Query: 303 EGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELA 362
E D E + G E+G LK+KQRR RT FTS QL+ELE FQ+ YPD+ TREE+A
Sbjct: 37 EHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 96
Query: 363 MRLDLTEARVQVWFQNRRAKWRKREKA--------------GAQTHPPGLPFPGPLSATH 408
+ +LTEARV+VWF+NRRAKWRKRE++ G P +PG
Sbjct: 97 VWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNW 156
Query: 409 P---LSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPG-SASLPPSGAPLGLST 464
P L+P L A FP A+ + A+ P PP +AS+ PS A T
Sbjct: 157 PPKALAPPLAAKTFP-------FAFNSVNVGPLASQPVFSPPSSIAASMVPSAA-AAPGT 208
Query: 465 FLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAA 524
G + P +AP +S A + P A A+ A A
Sbjct: 209 VPGPGALQGLGGGPPG-------LAPAAVSSGAVS-----CPYASAAAAAAAAASSPYVY 256
Query: 525 ADRRASSIAALRLKAKEHAA 544
D SS+A+LRLKAK+HA+
Sbjct: 257 RDPCNSSLASLRLKAKQHAS 276
Score = 29.6 bits (65), Expect = 7.7
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 101 AAAAAAAAAAAAAAATATAGPR-----GEAPPPPPPTARPGERPDGAGAAAAAAAAAAAA 155
++ AA+ +AAAA GP G PP P A A+AAAAAAAAA+
Sbjct: 192 SSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAAS 251
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 123 bits (308), Expect = 5e-28
Identities = 105/329 (31%), Positives = 145/329 (44%), Gaps = 57/329 (17%)
Query: 255 DARALL--KEPRRCPVAATGAVAAAAAAAVA-----TEGGELSPKEE----------LLL 297
DA LL +E +C + G+ +A EG L P E+ L +
Sbjct: 16 DAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAV 75
Query: 298 HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
+D + + G + + ++G ++KQ+R+RT FT QL ELER+F KTHYPD+F
Sbjct: 76 SAKDPDKQPGPQGGPNPSQAGQQQG--QQKQKRHRTRFTPAQLNELERSFAKTHYPDIFM 133
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDAS 417
REELA+R+ LTE+RVQVWFQNRRAKW+KR+K PG P P P + A+
Sbjct: 134 REELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAA 193
Query: 418 PFPP---HHPALDSAWTAAAAAAAAAFPSLPPPPG------------SASLPPSGAPLGL 462
A D+ W AAA + P LPP G S + P +GL
Sbjct: 194 AMGDSLCSFHANDTRWAAAAMPGVSQLP-LPPALGRQQAMAQSLSQCSLAAGPPPNSMGL 252
Query: 463 STFL----GAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALA 518
S L GA + H PAF ++ P S L
Sbjct: 253 SNSLAGSNGAGLQSH--LYQPAF----------------PGMVPASLPGPSNVSGSPQLC 294
Query: 519 DPATAAADRRASSIAALRLKAKEHAAQLT 547
++ R +SIA+LR KA EH ++
Sbjct: 295 SSPDSSDVWRGTSIASLRRKALEHTVSMS 323
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 123 bits (308), Expect = 5e-28
Identities = 105/329 (31%), Positives = 145/329 (44%), Gaps = 57/329 (17%)
Query: 255 DARALL--KEPRRCPVAATGAVAAAAAAAVA-----TEGGELSPKEE----------LLL 297
DA LL +E +C + G+ +A EG L P E+ L +
Sbjct: 16 DAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAV 75
Query: 298 HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
+D + + G + + ++G ++KQ+R+RT FT QL ELER+F KTHYPD+F
Sbjct: 76 SAKDPDKQPGPQGGPNPSQAGQQQG--QQKQKRHRTRFTPAQLNELERSFAKTHYPDIFM 133
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDAS 417
REELA+R+ LTE+RVQVWFQNRRAKW+KR+K PG P P P + A+
Sbjct: 134 REELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAA 193
Query: 418 PFPP---HHPALDSAWTAAAAAAAAAFPSLPPPPG------------SASLPPSGAPLGL 462
A D+ W AAA + P LPP G S + P +GL
Sbjct: 194 AMGDSLCSFHANDTRWAAAAMPGVSQLP-LPPALGRQQAMAQSLSQCSLAAGPPPNSMGL 252
Query: 463 STFL----GAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALA 518
S L GA + H PAF ++ P S L
Sbjct: 253 SNSLAGSNGAGLQSH--LYQPAF----------------PGMVPASLPGPSNVSGSPQLC 294
Query: 519 DPATAAADRRASSIAALRLKAKEHAAQLT 547
++ R +SIA+LR KA EH ++
Sbjct: 295 SSPDSSDVWRGTSIASLRRKALEHTVSMS 323
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 122 bits (305), Expect = 1e-27
Identities = 73/159 (45%), Positives = 94/159 (59%), Gaps = 14/159 (8%)
Query: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384
K K+RR RTTF+++QLEELE+ FQKTHYPDV+ RE+LA+R DLTEARVQVWFQNRRAKWR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 385 KREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSL 444
KRE+ G P +A + +S P HP L ++ A+ + + P L
Sbjct: 210 KRERYGKIQEG-----RNPFTAAYDIS----VLPRTDSHPQLQNSLWASPGSGSPGGPCL 260
Query: 445 PPPPG--SASLPPSGAPLG-LSTFLG--AAVFRHPAFIS 478
P G S + P P G ++ F+G A HP S
Sbjct: 261 VSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYS 299
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 119 bits (297), Expect = 1e-26
Identities = 82/189 (43%), Positives = 100/189 (52%), Gaps = 18/189 (9%)
Query: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384
KRKQRR RTTFTS QL+ELER F +THYPD++TREELA+++DLTEARVQVWFQNRRAK+R
Sbjct: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
Query: 385 KREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSL 444
K+E+A + G G S D S P DS SL
Sbjct: 147 KQERAASAKGAAGA--AGAKKGEARCSSEDDDSKESTCSPTPDST------------ASL 192
Query: 445 PPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTS---ASTAAALL 501
PPPP P +P L LG+ P P G L++ +A + AA LL
Sbjct: 193 PPPPAPGLASPRLSPSPLPVALGSGPGPGPG-PQPLKGALWAGVAGGGGGGPGAGAAELL 251
Query: 502 RQPTPAVEG 510
+ PA G
Sbjct: 252 KAWQPAESG 260
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 19/100 (19%)
Query: 138 RPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPP---------- 187
+ + A +A AA AA A + S S + S + +PPPP
Sbjct: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206
Query: 188 ------ALDELGGPGGVTHPEER---LGVAGGPGSAPAAG 218
AL GPG P + GVAGG G P AG
Sbjct: 207 PSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAG 246
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 118 bits (295), Expect = 2e-26
Identities = 65/129 (50%), Positives = 81/129 (62%), Gaps = 11/129 (8%)
Query: 307 GEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLD 366
GE G E K+K RR RTTFT+YQL +LERAF+ +HYPDV++REELA ++
Sbjct: 6 GEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVH 65
Query: 367 LTEARVQVWFQNRRAKWRKREK----AGAQTHP-----PGLPFPGPLSATHPLSPYLDAS 417
L E RVQVWFQNRRAKWR++E+ +GA P P LPF P + + PL P+L
Sbjct: 66 LPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWL--G 123
Query: 418 PFPPHHPAL 426
P PP P L
Sbjct: 124 PGPPAVPGL 132
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 114 bits (285), Expect = 2e-25
Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)
Query: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
+G G+ L GSD SE L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 189 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 248
Query: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406
ELA R LTEARVQVWF NRRA+WRK+ A A H P G+P P +
Sbjct: 249 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 308
Query: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438
T+P + H P + AAAAAAA
Sbjct: 309 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 114 bits (285), Expect = 2e-25
Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)
Query: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
+G G+ L GSD SE L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 187 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 246
Query: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406
ELA R LTEARVQVWF NRRA+WRK+ A A H P G+P P +
Sbjct: 247 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 306
Query: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438
T+P + H P + AAAAAAA
Sbjct: 307 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 344
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 114 bits (285), Expect = 2e-25
Identities = 76/158 (48%), Positives = 91/158 (57%), Gaps = 22/158 (13%)
Query: 303 EGKDGEDSVCLSAGSD--SEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
+G G+ L GSD SE L LKRKQRR RTTFT+ QLEELE+AF++THYPD++TRE
Sbjct: 189 DGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTRE 248
Query: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREKA---GAQTH-------PPGLPFPGPL---SA 406
ELA R LTEARVQVWF NRRA+WRK+ A A H P G+P P +
Sbjct: 249 ELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDS 308
Query: 407 THPLSPYLDASPFPPHHP------ALDSAWTAAAAAAA 438
T+P + H P + AAAAAAA
Sbjct: 309 TYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 112 bits (281), Expect = 7e-25
Identities = 52/67 (77%), Positives = 62/67 (92%)
Query: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384
KRKQRR RTTFTS QL+ELER F +THYPD++TREELA+++DLTEARVQVWFQNRRAK+R
Sbjct: 95 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154
Query: 385 KREKAGA 391
K+E+A A
Sbjct: 155 KQERAAA 161
Score = 48.5 bits (114), Expect = 2e-05
Identities = 37/77 (48%), Positives = 41/77 (53%), Gaps = 21/77 (27%)
Query: 90 GPGGGRLLQGAAAAAAAAAAAAAAAATATAG--------PRGEAPPPPPPTARPG----- 136
GPGG GAAAAAAAAAAAAAAAA A AG +G AP P P T+ P
Sbjct: 231 GPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGPITSIPDSLGGP 290
Query: 137 --------ERPDGAGAA 145
+RP+GA AA
Sbjct: 291 FASVLSSLQRPNGAKAA 307
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/95 (33%), Positives = 40/95 (42%), Gaps = 15/95 (15%)
Query: 102 AAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKI 161
A + A A AGP G PG P GAAAAAAAAAAAA
Sbjct: 210 ANGGGGGGPSPAGAPGAAGPGG-----------PGGEPGKGGAAAAAAAAAAAA---AAA 255
Query: 162 SQAPQVSISRSKSYRENGAPFVPPPPAL-DELGGP 195
+ A ++ + + AP P ++ D LGGP
Sbjct: 256 AAAAAGGLAAAGGPGQGWAPGPGPITSIPDSLGGP 290
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 138 RPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENG--APFVPPPPALDELGGP 195
+ + A AAAAAAA ++ S+ + ++S G P P P+ GG
Sbjct: 155 KQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGG 214
Query: 196 GGVTHPEERLGVA--GGPGSAPAAGG 219
GG P G A GGPG P GG
Sbjct: 215 GGGPSPAGAPGAAGPGGPGGEPGKGG 240
Score = 34.3 bits (77), Expect = 0.31
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 11/78 (14%)
Query: 145 AAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEER 204
AAAAAAAAA + K S + SR +E A P D GGPG +P
Sbjct: 159 AAAAAAAAAKNGSSGKKSDS-----SRDDESKE--AKSTDP----DSTGGPGPNPNPTPS 207
Query: 205 LGVAGGPGSAPAAGGGTG 222
G GG G P+ G G
Sbjct: 208 CGANGGGGGGPSPAGAPG 225
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 198 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 247
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 248 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 279
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 199 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 199 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 199 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 199 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 111 bits (278), Expect = 2e-24
Identities = 59/92 (64%), Positives = 67/92 (72%), Gaps = 11/92 (11%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGL-LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFT 357
P+ EG D DSE L LKRKQRR RTTFT+ QLEELERAF++THYPD++T
Sbjct: 199 PQSDEGSD----------IDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYT 248
Query: 358 REELAMRLDLTEARVQVWFQNRRAKWRKREKA 389
REELA R LTEARVQVWF NRRA+WRK+ A
Sbjct: 249 REELAQRAKLTEARVQVWFSNRRARWRKQAGA 280
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 111 bits (278), Expect = 2e-24
Identities = 134/460 (29%), Positives = 171/460 (37%), Gaps = 83/460 (18%)
Query: 82 PPKLRRLYGPGG-GRLLQGAAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPD 140
PP R++G GRL +G A A A AAA A R P P+
Sbjct: 374 PPAGARVFGVWARGRLRRGCHKCADRAPRAPKAAAKAAPAKRTARRRXXXXDTVPAA-PE 432
Query: 141 GAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYREN-----------GAPFVPPP--- 186
GAGAA AA ++ L I + + R + AP P P
Sbjct: 433 GAGAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAAS 492
Query: 187 ---PALDEL-----GGPGGVTHPEERLGVAGGPGSAPAA-----------GGGTGTEDDE 227
P +EL G GGV AG P A A GGG D
Sbjct: 493 GRPPRAEELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADS 552
Query: 228 EELLEDEEDEDEEEELLEDDEEELLEDDARA----LLKEPRRCPVAAT-----GAVAAAA 278
+ + D+ED+DE+E + E ++AR L C AA GA A
Sbjct: 553 GDEVPDDEDDDEDEA--PETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEA 610
Query: 279 AAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLS------AGSDSEEGLLKRKQRRYR 332
AA E ++P G + + + GSDS+ G K RR R
Sbjct: 611 AAPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSG----KPRRAR 666
Query: 333 TTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQ 392
T FT QL LE F+ T Y V R LA+ L LTE +V++WFQNRR KW+K+
Sbjct: 667 TAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADT 726
Query: 393 THP------------PGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAA 440
+ P PG PG LS P P +P H PA A AA
Sbjct: 727 SAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPM--GAPLGMHGPAGYPAHGPGGLVCAAQ 784
Query: 441 FPSLPPPPGSASLPPSGAPLGLSTF-LGAAVFRHPAFISP 479
P L +P LS F LG+ + PAF +P
Sbjct: 785 LPFL------------SSPAVLSPFVLGSQTYGAPAFYAP 812
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 109 bits (273), Expect = 6e-24
Identities = 77/174 (44%), Positives = 92/174 (52%), Gaps = 26/174 (14%)
Query: 268 VAATGAVAAAAAA-AVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKR 326
VAA G +AA A A A EG P +A +DGE C S G S K+
Sbjct: 49 VAAAGRLAARPGARAEAREGAAREPSGGS--SGSEAAPQDGE---CPSPGRGSA-AKRKK 102
Query: 327 KQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKR 386
KQRR RTTF S QL+ LER F++THYPD F REELA R++L+EARVQVWFQNRRAK+R+
Sbjct: 103 KQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRN 162
Query: 387 EKA---------------GAQTHPPGLPFPGPLSATH----PLSPYLDASPFPP 421
E+A A P P P LS + SPY P+ P
Sbjct: 163 ERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSP 216
Score = 30.4 bits (67), Expect = 4.5
Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 111 AAAAATATAGPR-GEAPPPPPPTARPGE 137
+AAAA A P G PPPPPP PG+
Sbjct: 3 SAAAAFALDKPALGPGPPPPPPALGPGD 30
>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
Length = 190
Score = 108 bits (271), Expect = 1e-23
Identities = 88/231 (38%), Positives = 107/231 (46%), Gaps = 49/231 (21%)
Query: 320 EEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNR 379
+EG K KQRR RT FT QL ELER F +THYPD F REEL+ RL L+EARVQVWFQNR
Sbjct: 3 DEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNR 62
Query: 380 RAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDAS----PFPPHHPALDSAWTAAAA 435
RAK RK+E Q H L ++PY++ PF L +A A
Sbjct: 63 RAKCRKQEN---QLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLD-SAVAH 118
Query: 436 AAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSAS 495
A P L AA + F +P FG +T+
Sbjct: 119 AHHHLHPHL-----------------------AAHAPYMMFPAPPFGLPLATL------- 148
Query: 496 TAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQL 546
A + A A+ +A A A + SSIA LRLKAK+HAA L
Sbjct: 149 -----------AADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAAL 188
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 108 bits (269), Expect = 2e-23
Identities = 88/253 (34%), Positives = 132/253 (52%), Gaps = 24/253 (9%)
Query: 299 PEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTR 358
PE AE + G+ E+ K++QRR RT FTS QL+ELE FQ+ YPD+ TR
Sbjct: 65 PEAAEKDKSQQGKNEDVGA--EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTR 122
Query: 359 EELAMRLDLTEARVQVWFQNRRAKWRKREK-AGAQTHPPGLPFPGPLSATHPLSPYLDAS 417
EE+A+ +LTEARV+VWF+NRRAKWRKRE+ A+ G GP + PY D
Sbjct: 123 EEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGF---GP-QFNGLMQPYDDMY 178
Query: 418 PFPPHHPALDSAWTAAAAAAAA--AFPSLPPPPGSA----SLPPSGAPLGLSTFLGAAVF 471
P ++ T+A+ + + F S+ P S+ S P S + + +S+ +
Sbjct: 179 PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSM----- 233
Query: 472 RHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASS 531
P+ ++ G +++ L + S+ + PTPA A + P D SS
Sbjct: 234 -VPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPT-----PPYVYRDTCNSS 287
Query: 532 IAALRLKAKEHAA 544
+A+LRLKAK+H++
Sbjct: 288 LASLRLKAKQHSS 300
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 108 bits (269), Expect = 2e-23
Identities = 93/259 (35%), Positives = 116/259 (44%), Gaps = 44/259 (16%)
Query: 288 ELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAF 347
E+SP EL EDA+G + +EG K KQRR RT FT QL ELER F
Sbjct: 115 EVSP--ELKDRKEDAKGME-------------DEGQTKIKQRRSRTNFTLEQLNELERLF 159
Query: 348 QKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSAT 407
+THYPD F REEL+ RL L+EARVQVWFQNRRAK RK+E Q H L
Sbjct: 160 DETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQEN---QLHKGVLIGAASQFEA 216
Query: 408 HPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLG 467
++PY++ A P ++ P + L
Sbjct: 217 CRVAPYVN--------------------VGALRMPF--QQDSHCNVTPLSFQVQAQLQLD 254
Query: 468 AAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADR 527
+AV + P + AP L T A + A A+ +A A A
Sbjct: 255 SAVAHAHHHLHPH----LAAHAPYMMFPAPPFGLPLATLAADSASAASVVAAAAAAKTTS 310
Query: 528 RASSIAALRLKAKEHAAQL 546
+ SSIA LRLKAK+HAA L
Sbjct: 311 KNSSIADLRLKAKKHAAAL 329
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 107 bits (267), Expect = 3e-23
Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 22/233 (9%)
Query: 319 SEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQN 378
+E+ K++QRR RT FTS QL+ELE FQ+ YPD+ TREE+A+ +LTEARV+VWF+N
Sbjct: 30 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 89
Query: 379 RRAKWRKREK-AGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAA 437
RRAKWRKRE+ A+ G GP + PY D P ++ T+A+ +
Sbjct: 90 RRAKWRKRERNQQAELCKNGF---GP-QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLST 145
Query: 438 AA--AFPSLPPPPGSA----SLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPL 491
+ F S+ P S+ S P S + + +S+ + P+ ++ G +++ L
Sbjct: 146 KSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSM------VPSAVTGVPGSSLNSLNNL 199
Query: 492 TSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAA 544
+ S+ + PTPA A + P D SS+A+LRLKAK+H++
Sbjct: 200 NNLSSPSLNSAVPTPACPYAPPT-----PPYVYRDTCNSSLASLRLKAKQHSS 247
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 107 bits (267), Expect = 3e-23
Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 22/233 (9%)
Query: 319 SEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQN 378
+E+ K++QRR RT FTS QL+ELE FQ+ YPD+ TREE+A+ +LTEARV+VWF+N
Sbjct: 76 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 135
Query: 379 RRAKWRKREK-AGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAA 437
RRAKWRKRE+ A+ G GP + PY D P ++ T+A+ +
Sbjct: 136 RRAKWRKRERNQQAELCKNGF---GP-QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLST 191
Query: 438 AA--AFPSLPPPPGSA----SLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPL 491
+ F S+ P S+ S P S + + +S+ + P+ ++ G +++ L
Sbjct: 192 KSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSM------VPSAVTGVPGSSLNSLNNL 245
Query: 492 TSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAA 544
+ S+ + PTPA A + P D SS+A+LRLKAK+H++
Sbjct: 246 NNLSSPSLNSAVPTPACPYAPPT-----PPYVYRDTCNSSLASLRLKAKQHSS 293
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 106 bits (265), Expect = 5e-23
Identities = 48/64 (75%), Positives = 56/64 (87%)
Query: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384
KRK+RR+RT FTSYQLEELE+AF + HYPDV+ RE LAM+ +L E R+QVWFQNRRAKWR
Sbjct: 145 KRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWR 204
Query: 385 KREK 388
KREK
Sbjct: 205 KREK 208
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 105 bits (263), Expect = 8e-23
Identities = 67/155 (43%), Positives = 91/155 (58%), Gaps = 18/155 (11%)
Query: 307 GEDSVCLSA-GSDSEEGL----LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREEL 361
GE++ +S+ G DS+E LKRK +R RT+FT Q+E LE+ F++THYPDVF RE L
Sbjct: 184 GENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERL 243
Query: 362 AMRLDLTEARVQVWFQNRRAKWRKREKAGAQ-THPPGLPFPGPLSATHPLSPYLDASPFP 420
A ++DL EAR+QVWF NRRAKWR+ EK Q P P+S++ S Y P P
Sbjct: 244 AAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVY---QPIP 300
Query: 421 -PHHPALDSAWTAAA------AAAAAAFPSLPPPP 448
P P S++T+ + A + +LPP P
Sbjct: 301 QPTTPV--SSFTSGSMLGRTDTALTNTYSALPPMP 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,149,273
Number of Sequences: 37866
Number of extensions: 1898872
Number of successful extensions: 51093
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1121
Number of HSP's successfully gapped in prelim test: 1357
Number of HSP's that attempted gapping in prelim test: 20897
Number of HSP's gapped (non-prelim): 18176
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.