Guide to the Human Genome
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Search of human proteins with 24497585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24497585 aldo-keto reductase family 1, member C4 [Homo
sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    662   0.0  
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     558   e-159
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    558   e-159
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    548   e-156
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     548   e-156
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     387   e-108
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     318   5e-87
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   302   2e-82
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   288   6e-78
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   273   1e-73
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    266   1e-71
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     266   1e-71
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         202   2e-52
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...    55   1e-07
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...    55   1e-07
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]     50   2e-06
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]     44   1e-04
gi|157266300 membrane alanine aminopeptidase precursor [Homo sap...    36   0.053
gi|27436964 potassium voltage-gated channel, shaker-related subf...    33   0.34 
gi|27436962 potassium voltage-gated channel, shaker-related subf...    33   0.34 
gi|27436966 potassium voltage-gated channel, shaker-related subf...    33   0.34 
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    32   0.76 
gi|27436969 potassium voltage-gated channel, shaker-related subf...    32   0.76 
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...    30   2.9  
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...    30   2.9  
gi|27436971 potassium voltage-gated channel, shaker-related subf...    29   6.5  

>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  662 bits (1707), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ
Sbjct: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
           ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
           LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
           RNYRYVVMDFLMDHPDYPFSDEY
Sbjct: 301 RNYRYVVMDFLMDHPDYPFSDEY 323


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  558 bits (1438), Expect = e-159
 Identities = 267/323 (82%), Positives = 296/323 (91%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E TKLAIEAGFRHIDSA+LYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWC   +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
           ++KPGE  +PKDENGK++FDTVDL ATWE +EKCKDAGLAKSIGVSNFN RQLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
           RN RY+ +D     P+YPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  558 bits (1437), Expect = e-159
 Identities = 271/323 (83%), Positives = 295/323 (91%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MD K+Q V+LNDGHFMPVLGFGTYAPPEVPR++A+EVTKLAIEAGFRHIDSA+LYNNEEQ
Sbjct: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW TF +P++V+PALE+SLKK QLDYVDLYL+H PM
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
           +LKPGE   P DENGKVIFD VDL  TWE MEKCKDAGLAKSIGVSNFN RQLEMILNKP
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY N+SKLLDFCKSKDIVLVA+SALG+QR K WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLT+EDMK +DGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
           RN  Y   D    HP+YP+SDEY
Sbjct: 301 RNLHYFNSDSFASHPNYPYSDEY 323


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  548 bits (1412), Expect = e-156
 Identities = 263/323 (81%), Positives = 292/323 (90%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E  KLAIEAGF HIDSA++YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW    +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
           ++KPGE  +PKDENGK++FDTVDL ATWE MEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
           RN RY+ +D     P+YPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  548 bits (1412), Expect = e-156
 Identities = 263/323 (81%), Positives = 292/323 (90%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E  KLAIEAGF HIDSA++YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW    +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
           ++KPGE  +PKDENGK++FDTVDL ATWE MEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNYRYVVMDFLMDHPDYPFSDEY 323
           RN RY+ +D     P+YPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  387 bits (993), Expect = e-108
 Identities = 181/318 (56%), Positives = 239/318 (75%), Gaps = 1/318 (0%)

Query: 7   RVELNDGHFMPVLGFGTYAPPE-VPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 65
           R+ L+DG+ +P++G GTY+ P+  P+       K+AI+ G+RHID AY+Y NE +VG AI
Sbjct: 9   RIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAI 68

Query: 66  RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
           R KIA+G V+REDIFY  KLW T   P+MV+P LE +L+ LQLDYVDLY++  PMA KPG
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG 128

Query: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
           +   P+DENGK ++   +L ATWE ME CKDAGL KS+GVSNFN RQLE+ILNKPGLK+K
Sbjct: 129 DEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHK 188

Query: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALA 245
           PV NQVECHPY  Q KLL FC+  DIV+ A+S LGT R+ +WV+ +SP LL+D +L +L 
Sbjct: 189 PVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLG 248

Query: 246 KKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRY 305
           K++ +T A I LR+ +QRGVVV+ KS+N +RI+EN Q+F+F LT E+MK ++ LN+N R+
Sbjct: 249 KRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRF 308

Query: 306 VVMDFLMDHPDYPFSDEY 323
           V +    DHP+YPF DEY
Sbjct: 309 VELLMWRDHPEYPFHDEY 326


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  318 bits (814), Expect = 5e-87
 Identities = 152/317 (47%), Positives = 215/317 (67%), Gaps = 4/317 (1%)

Query: 7   RVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIR 66
           R+ LN+G  MP+LG GT+  P     +  E  K+AI+ G+RHID A++Y NE +VG+AI+
Sbjct: 4   RLLLNNGAKMPILGLGTWKSPP---GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 67  SKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            K+ +  VKRE++F  SKLWCT+ +  +V+ A + +L  L+LDY+DLYL+H+P   KPG+
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKP 186
              P DE+G V+    ++  TW  ME+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 246
             NQ+ECHPYL Q KL+ +C+SK IV+ A+S LG+   + W  P  P LLEDP + A+A 
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAA 239

Query: 247 KHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 306
           KH +T A + +R+ +QR +VV+ KS   +RI EN +VF+F+L+S+DM  L   NRN+R  
Sbjct: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 299

Query: 307 VMDFLMDHPDYPFSDEY 323
            +     H DYPF +E+
Sbjct: 300 ALLSCTSHKDYPFHEEF 316


>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  302 bits (774), Expect = 2e-82
 Identities = 152/316 (48%), Positives = 207/316 (65%), Gaps = 4/316 (1%)

Query: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
           VEL+    MP++G GT+   + P  +  E  K+AI+AG+RHID AY+Y NE +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
           KI + +VKRED+F  SKLW TFF+  +V+ A E +LK L+L Y+D+YL+H+P   K G+ 
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121

Query: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
             PKD+ G  I         WE ME+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181

Query: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPYL Q KL+ +C SK I + A+S LG+   + W  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVV 307
           HK+T A + +R+ +QR V+V+ KS    RI ENIQVF+F+L+ E+M  +   NRN+R   
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 308 MDFLMDHPDYPFSDEY 323
           +       DYPF+ EY
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  288 bits (736), Expect = 6e-78
 Identities = 146/316 (46%), Positives = 199/316 (62%), Gaps = 4/316 (1%)

Query: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
           VEL+    MP++G GT+        +  E  K+AI+A +RHID AY Y N+ +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTWRSL---LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGET 127
           KI + +V RED+F  SK+W TFF+  +V+ A E +LK L+L Y+D+YL+H+P   K G+ 
Sbjct: 62  KIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDD 121

Query: 128 PLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPV 187
             PKD+ G +I         WE ME+  D GL K++GVSNFN  Q+E +LNKPGLKYKPV
Sbjct: 122 FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPV 181

Query: 188 CNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPYL Q KL+ +C SK I + A+S LG+   + W  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVV 307
           HK+T A + +R+ +QR V V+ KS     I ENIQVF+F+L+ E+M  +   NRN+R   
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 308 MDFLMDHPDYPFSDEY 323
                   D+PF  EY
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  273 bits (699), Expect = 1e-73
 Identities = 142/327 (43%), Positives = 197/327 (60%), Gaps = 29/327 (8%)

Query: 16  MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 75
           +P +G  ++   +    +  E  K AI+AG+RH D AY Y+NE +VG  IR KI +G+V+
Sbjct: 4   IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60

Query: 76  REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE--------- 126
           RED+F  +KLWCT  +  +V+ A   SLK L+L+Y+DLYL+H+PM  KP           
Sbjct: 61  REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120

Query: 127 ----------TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMI 176
                       LP DE+  VI    D   TWE ME     GL K+IGVSNFN  QLE +
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180

Query: 177 LNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLL 236
           LNKPGL++KP+ NQ+ECHPYL Q  L+ FC+S+D+ + A+  LG       VD     L+
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233

Query: 237 EDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVL 296
           ++PV+  +AK+H ++PA I +R+Q+QR V+V+  S     I+ENIQVF+F+LT  DM  +
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293

Query: 297 DGLNRNYRYVVMDFLMDHPDYPFSDEY 323
             LNRN R  +     +H DYPF  EY
Sbjct: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  266 bits (681), Expect = 1e-71
 Identities = 137/326 (42%), Positives = 210/326 (64%), Gaps = 16/326 (4%)

Query: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
           V L+ G  MP++G GT+         AV   K A+  G+RHID A +Y NE ++G A++ 
Sbjct: 6   VLLHTGQKMPLIGLGTWKSEPGQVKAAV---KYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 68  KIADG-SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +  G +V RE++F TSKLW T   P+ V+PAL  +L  LQL+Y+DLYL+H+P A + G+
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKP 186
            P PK+ +G + +D+     TW+ +E     GL +++G+SNFN RQ++ IL+   +  +P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--RP 180

Query: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 246
              QVECHPYL Q++L+  C+++ + + A+S LG+   + W DP+ PVLLE+PV+ ALA+
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALAE 239

Query: 247 KHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 306
           K+ ++PA I LR+Q+QR V+ + KS    RI +NI+VF+F  + E+MK L+ LN+N+RY+
Sbjct: 240 KYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299

Query: 307 VMDFLMD---------HPDYPFSDEY 323
           V    +D         HP YPF+D Y
Sbjct: 300 VPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  266 bits (681), Expect = 1e-71
 Identities = 137/326 (42%), Positives = 210/326 (64%), Gaps = 16/326 (4%)

Query: 8   VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRS 67
           V L+ G  MP++G GT+         AV   K A+  G+RHID A +Y NE ++G A++ 
Sbjct: 6   VLLHTGQKMPLIGLGTWKSEPGQVKAAV---KYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 68  KIADG-SVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +  G +V RE++F TSKLW T   P+ V+PAL  +L  LQL+Y+DLYL+H+P A + G+
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKP 186
            P PK+ +G + +D+     TW+ +E     GL +++G+SNFN RQ++ IL+   +  +P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--RP 180

Query: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 246
              QVECHPYL Q++L+  C+++ + + A+S LG+   + W DP+ PVLLE+PV+ ALA+
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALAE 239

Query: 247 KHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 306
           K+ ++PA I LR+Q+QR V+ + KS    RI +NI+VF+F  + E+MK L+ LN+N+RY+
Sbjct: 240 KYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299

Query: 307 VMDFLMD---------HPDYPFSDEY 323
           V    +D         HP YPF+D Y
Sbjct: 300 VPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  202 bits (515), Expect = 2e-52
 Identities = 96/123 (78%), Positives = 111/123 (90%)

Query: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E  KLAIEAGF HIDSA++YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW    +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 ALK 123
           ++K
Sbjct: 121 SVK 123


>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 15/137 (10%)

Query: 37  VTKLAIEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWC-TFFQ 91
           VT+  +E G   ID+A+LY++ +      GL +R   +D  VK   I   +  W     +
Sbjct: 31  VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKANPWIGNSLK 87

Query: 92  PQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL----PKDENGKVIFDTVDLSAT 147
           P  V+  LE+SLK+LQ   VDL+ LH P    P E  L       + GK +   +   A 
Sbjct: 88  PDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNYAA 147

Query: 148 WEVMEKCKDAGLAKSIG 164
           WEV E C    L KS G
Sbjct: 148 WEVAEICT---LCKSNG 161


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 15/137 (10%)

Query: 37  VTKLAIEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWC-TFFQ 91
           VT+  +E G   ID+A+LY++ +      GL +R   +D  VK   I   +  W     +
Sbjct: 31  VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKANPWIGNSLK 87

Query: 92  PQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL----PKDENGKVIFDTVDLSAT 147
           P  V+  LE+SLK+LQ   VDL+ LH P    P E  L       + GK +   +   A 
Sbjct: 88  PDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFVELGLSNYAA 147

Query: 148 WEVMEKCKDAGLAKSIG 164
           WEV E C    L KS G
Sbjct: 148 WEVAEICT---LCKSNG 161


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 44/136 (32%), Positives = 64/136 (47%), Gaps = 13/136 (9%)

Query: 37  VTKLAIEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWCTFFQP 92
           VT+  +E G   ID+A++Y+  +      GL +R   +D  VK +       L+    +P
Sbjct: 31  VTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAIPLFGNSLKP 88

Query: 93  QMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL----PKDENGKVIFDTVDLSATW 148
             ++  LE+SLK+LQ   VDL+ LH P    P E  L       + GK +   +   A W
Sbjct: 89  DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAW 148

Query: 149 EVMEKCKDAGLAKSIG 164
           EV E C    L KS G
Sbjct: 149 EVAEICT---LCKSNG 161


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 15/132 (11%)

Query: 42  IEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWC-TFFQPQMVQ 96
           +E G   +D+A++Y++ +      GL +     D  VK   I   +  W     +P  V+
Sbjct: 64  LERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKANPWDGKSLKPDSVR 120

Query: 97  PALESSLKKLQLDYVDLYLLHFPMALKPGETPLPK----DENGKVIFDTVDLSATWEVME 152
             LE+SLK+LQ   VDL+ LH P    P E  L       + GK +   +   A+WEV E
Sbjct: 121 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE 180

Query: 153 KCKDAGLAKSIG 164
            C    L KS G
Sbjct: 181 ICT---LCKSNG 189


>gi|157266300 membrane alanine aminopeptidase precursor [Homo
           sapiens]
          Length = 967

 Score = 35.8 bits (81), Expect = 0.053
 Identities = 40/151 (26%), Positives = 69/151 (45%), Gaps = 15/151 (9%)

Query: 10  LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIE--AGFRHIDSAYLYNNEEQVGLA--- 64
           L+ GH + + G G   PP++ +   VE T+  +    G    DS Y  ++E +  LA   
Sbjct: 131 LSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDL 190

Query: 65  ---IRSKIADGSVKREDIFYTSKLWCTFFQ---PQMVQPALESSLKKLQLDYVDLYLLHF 118
               RS+  +G+V++  +  T+++     +   P   +PA+++      +   DL  L  
Sbjct: 191 AGFYRSEYMEGNVRK--VVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALS- 247

Query: 119 PMALKPGETPLPKDENGKVI-FDTVDLSATW 148
            M  K   TPLP+D N  V  F T    +T+
Sbjct: 248 NMLPKGPSTPLPEDPNWNVTEFHTTPKMSTY 278


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 86  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +R  +  T+KL+             + +   L+ SL++LQL+YVD+   + P      +
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 195

Query: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
           +  P +E  + +   ++        ++ W  ME  +   +A          RQ  MI   
Sbjct: 196 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 242

Query: 180 PGLKYKPVCNQVECH 194
                 PVC Q E H
Sbjct: 243 -----PPVCEQAEYH 252


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 93  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +R  +  T+KL+             + +   L+ SL++LQL+YVD+   + P      +
Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 202

Query: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
           +  P +E  + +   ++        ++ W  ME  +   +A          RQ  MI   
Sbjct: 203 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 249

Query: 180 PGLKYKPVCNQVECH 194
                 PVC Q E H
Sbjct: 250 -----PPVCEQAEYH 259


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +R  +  T+KL+             + +   L+ SL++LQL+YVD+   + P      +
Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 213

Query: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179
           +  P +E  + +   ++        ++ W  ME  +   +A          RQ  MI   
Sbjct: 214 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 260

Query: 180 PGLKYKPVCNQVECH 194
                 PVC Q E H
Sbjct: 261 -----PPVCEQAEYH 270


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 32.0 bits (71), Expect = 0.76
 Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 29/175 (16%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A ++  LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 52  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 107

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +R  +  T+K++             + +   L++SL++LQL+YVD+   + P      +
Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP------D 161

Query: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
              P +E  + +   ++        ++ W  ME  +   +A+   ++   C Q E
Sbjct: 162 PNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAE 216


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 32.0 bits (71), Expect = 0.76
 Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 29/175 (16%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A ++  LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 38  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 93

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126
            +R  +  T+K++             + +   L++SL++LQL+YVD+   + P      +
Sbjct: 94  WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP------D 147

Query: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
              P +E  + +   ++        ++ W  ME  +   +A+   ++   C Q E
Sbjct: 148 PNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAE 202


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSN 167
           P   N K +F  V+   T  V+E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSN 167
           P   N K +F  V+   T  V+E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 19  LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A +V  +A E G    D+A +Y     E  +G  ++SK     
Sbjct: 93  LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----G 148

Query: 74  VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDL 113
            +R     T+K++             + +   L  SL++LQL YVD+
Sbjct: 149 WRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,529,203
Number of Sequences: 37866
Number of extensions: 537295
Number of successful extensions: 1129
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1088
Number of HSP's gapped (non-prelim): 26
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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