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Search of human proteins with 24431933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24431933 reticulon 4 isoform B [Homo sapiens]
(373 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24431933 reticulon 4 isoform B [Homo sapiens] 740 0.0
gi|47519490 reticulon 4 isoform D [Homo sapiens] 729 0.0
gi|24431935 reticulon 4 isoform A [Homo sapiens] 383 e-106
gi|47519562 reticulon 4 isoform E [Homo sapiens] 363 e-100
gi|5902016 reticulon 4 isoform C [Homo sapiens] 361 e-100
gi|45827778 reticulon 1 isoform B [Homo sapiens] 287 1e-77
gi|10863935 reticulon 1 isoform A [Homo sapiens] 287 1e-77
gi|45827776 reticulon 1 isoform C [Homo sapiens] 268 8e-72
gi|5174655 reticulon 3 isoform a [Homo sapiens] 252 4e-67
gi|41393604 reticulon 3 isoform c [Homo sapiens] 245 4e-65
gi|41393608 reticulon 3 isoform b [Homo sapiens] 244 1e-64
gi|41393606 reticulon 3 isoform d [Homo sapiens] 215 5e-56
gi|46255005 reticulon 2 isoform B [Homo sapiens] 198 7e-51
gi|5032055 reticulon 2 isoform A [Homo sapiens] 194 1e-49
gi|46255007 reticulon 2 isoform C [Homo sapiens] 189 3e-48
gi|153792074 proline rich 12 [Homo sapiens] 78 1e-14
gi|33356148 formin-like 1 [Homo sapiens] 68 2e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 1e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 65 1e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 3e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 64 3e-10
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 62 1e-09
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 62 1e-09
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 62 1e-09
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 62 1e-09
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 61 2e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 61 2e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni... 61 2e-09
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 60 2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 2e-09
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 740 bits (1911), Expect = 0.0
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKG 240
SSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKG
Sbjct: 181 SSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKG 240
Query: 241 VIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSL 300
VIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSL
Sbjct: 241 VIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSL 300
Query: 301 KFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAK 360
KFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAK
Sbjct: 301 KFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAK 360
Query: 361 IQAKIPGLKRKAE 373
IQAKIPGLKRKAE
Sbjct: 361 IQAKIPGLKRKAE 373
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 729 bits (1881), Expect = 0.0
Identities = 373/392 (95%), Positives = 373/392 (95%), Gaps = 19/392 (4%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSV-------------------VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVT 221
SSGSV VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVT
Sbjct: 181 SSGSVDETLFALPAASEPVIRSSAVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVT 240
Query: 222 AYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVN 281
AYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVN
Sbjct: 241 AYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVN 300
Query: 282 CTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQA 341
CTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQA
Sbjct: 301 CTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQA 360
Query: 342 QIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 373
QIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
Sbjct: 361 QIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 392
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 383 bits (984), Expect = e-106
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSV 185
SSGSV
Sbjct: 181 SSGSV 185
Score = 363 bits (933), Expect = e-100
Identities = 198/241 (82%), Positives = 206/241 (85%), Gaps = 12/241 (4%)
Query: 145 PPPPASVSPQAE--PVWTPPAPAPAAPPSTPAAPKRRGSSGSV----------VVDLLYW 192
PP ++++ QAE + P A P+ ++ S S VVDLLYW
Sbjct: 952 PPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYW 1011
Query: 193 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 252
RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH
Sbjct: 1012 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 1071
Query: 253 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 312
PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV
Sbjct: 1072 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 1131
Query: 313 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 372
GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA
Sbjct: 1132 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 1191
Query: 373 E 373
E
Sbjct: 1192 E 1192
>gi|47519562 reticulon 4 isoform E [Homo sapiens]
Length = 986
Score = 363 bits (933), Expect = e-100
Identities = 198/241 (82%), Positives = 206/241 (85%), Gaps = 12/241 (4%)
Query: 145 PPPPASVSPQAE--PVWTPPAPAPAAPPSTPAAPKRRGSSGSV----------VVDLLYW 192
PP ++++ QAE + P A P+ ++ S S VVDLLYW
Sbjct: 746 PPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYW 805
Query: 193 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 252
RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH
Sbjct: 806 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 865
Query: 253 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 312
PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV
Sbjct: 866 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 925
Query: 313 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 372
GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA
Sbjct: 926 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 985
Query: 373 E 373
E
Sbjct: 986 E 986
>gi|5902016 reticulon 4 isoform C [Homo sapiens]
Length = 199
Score = 361 bits (927), Expect = e-100
Identities = 188/188 (100%), Positives = 188/188 (100%)
Query: 186 VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAI 245
VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAI
Sbjct: 12 VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAI 71
Query: 246 QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVL 305
QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVL
Sbjct: 72 QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVL 131
Query: 306 MWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKI 365
MWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKI
Sbjct: 132 MWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKI 191
Query: 366 PGLKRKAE 373
PGLKRKAE
Sbjct: 192 PGLKRKAE 199
>gi|45827778 reticulon 1 isoform B [Homo sapiens]
Length = 356
Score = 287 bits (734), Expect = 1e-77
Identities = 171/361 (47%), Positives = 218/361 (60%), Gaps = 28/361 (7%)
Query: 16 PPRP-QPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPV-PTAPA 73
PP P P+ +Y +RE E E E + E E + E P + P+ P+A
Sbjct: 21 PPSPASPSIQYSILRE----EREAELDSELIIESCDASSASEESPKREQDSPPMKPSALD 76
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKL 133
A + P+ RG A P + PS +P P P L
Sbjct: 77 AIREETGVRAEERAPSRRG---LAEPGSFLDYPSTEPQPGPELPPGDGAL---------- 123
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAP-APAAPPSTPAAPKRRGSSGSVVVDLLYW 192
+ E P P P S S Q+ P P P APP K++ +DLLYW
Sbjct: 124 --EPETPMLPRKPEEDSSSNQSPAATKGPGPLGPGAPPPLLFLNKQKA------IDLLYW 175
Query: 193 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 252
RDIK+TG+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK V+QA+QK+DEGH
Sbjct: 176 RDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGH 235
Query: 253 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 312
PF+AYLE E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSLKFAVLMW+ TYV
Sbjct: 236 PFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYV 295
Query: 313 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 372
GALFNGLTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AKIQAKIPG KR A
Sbjct: 296 GALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHA 355
Query: 373 E 373
E
Sbjct: 356 E 356
>gi|10863935 reticulon 1 isoform A [Homo sapiens]
Length = 776
Score = 287 bits (734), Expect = 1e-77
Identities = 171/361 (47%), Positives = 218/361 (60%), Gaps = 28/361 (7%)
Query: 16 PPRP-QPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPV-PTAPA 73
PP P P+ +Y +RE E E E + E E + E P + P+ P+A
Sbjct: 441 PPSPASPSIQYSILRE----EREAELDSELIIESCDASSASEESPKREQDSPPMKPSALD 496
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKL 133
A + P+ RG A P + PS +P P P L
Sbjct: 497 AIREETGVRAEERAPSRRG---LAEPGSFLDYPSTEPQPGPELPPGDGAL---------- 543
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAP-APAAPPSTPAAPKRRGSSGSVVVDLLYW 192
+ E P P P S S Q+ P P P APP K++ +DLLYW
Sbjct: 544 --EPETPMLPRKPEEDSSSNQSPAATKGPGPLGPGAPPPLLFLNKQKA------IDLLYW 595
Query: 193 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 252
RDIK+TG+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK V+QA+QK+DEGH
Sbjct: 596 RDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGH 655
Query: 253 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 312
PF+AYLE E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSLKFAVLMW+ TYV
Sbjct: 656 PFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYV 715
Query: 313 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 372
GALFNGLTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AKIQAKIPG KR A
Sbjct: 716 GALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHA 775
Query: 373 E 373
E
Sbjct: 776 E 776
Score = 33.1 bits (74), Expect = 0.41
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 24/145 (16%)
Query: 22 AFKYQFVREPEDEEEEEEEEEEDEDEDLE---ELEVLERKPAAGLSAAPVPTAPAAGAPL 78
A+KY + PE+ + +E+ E ED+DL+ + + KP P AP G +
Sbjct: 193 AYKYIDITRPEEVKHQEQHHPELEDKDLDFKNKDTDISIKPEG--VREPDKPAPVEGKII 250
Query: 79 MD----------FGNDFVPPAPRGPLPAAPP--VAPERQPSWDPSPVSSTVP------AP 120
D + +D R P P E +PS + + T P
Sbjct: 251 KDHLLEESTFAPYIDDLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKP 310
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPP 145
SP + V+ S+ PEDD P + PP
Sbjct: 311 SPDTVPTVTVSE-PEDDSPGSITPP 334
>gi|45827776 reticulon 1 isoform C [Homo sapiens]
Length = 208
Score = 268 bits (684), Expect = 8e-72
Identities = 129/190 (67%), Positives = 160/190 (84%)
Query: 184 SVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ 243
S +DLLYWRDIK+TG+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK V+Q
Sbjct: 19 SQAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQ 78
Query: 244 AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFA 303
A+QK+DEGHPF+AYLE E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSLKFA
Sbjct: 79 AVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFA 138
Query: 304 VLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQA 363
VLMW+ TYVGALFNGLTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AKIQA
Sbjct: 139 VLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQA 198
Query: 364 KIPGLKRKAE 373
KIPG KR AE
Sbjct: 199 KIPGAKRHAE 208
>gi|5174655 reticulon 3 isoform a [Homo sapiens]
Length = 236
Score = 252 bits (643), Expect = 4e-67
Identities = 123/215 (57%), Positives = 162/215 (75%), Gaps = 2/215 (0%)
Query: 161 PPAPAPAAPPST-PAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVS 219
P AP P PA + SS V DL++WRD+KKTG VFG +L +LLSL FS++S
Sbjct: 22 PSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVIS 81
Query: 220 VTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGH 279
V +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+ H
Sbjct: 82 VVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVH 141
Query: 280 VNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERH 339
+N +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE++
Sbjct: 142 INRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKY 201
Query: 340 QAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 373
+ QIDHY+G+A K + KIQAK+PG+ K+KAE
Sbjct: 202 KTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
>gi|41393604 reticulon 3 isoform c [Homo sapiens]
Length = 255
Score = 245 bits (626), Expect = 4e-65
Identities = 117/193 (60%), Positives = 155/193 (80%), Gaps = 1/193 (0%)
Query: 182 SGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGV 241
S S V DL++WRD+KKTG VFG +L +LLSL FS++SV +Y+ LALLSVTISFRIYK V
Sbjct: 63 STSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSV 122
Query: 242 IQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK 301
IQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+ H+N +K + RLFLV+DLVDSLK
Sbjct: 123 IQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLK 182
Query: 302 FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKI 361
AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE+++ QIDHY+G+A K + KI
Sbjct: 183 LAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKI 242
Query: 362 QAKIPGL-KRKAE 373
QAK+PG+ K+KAE
Sbjct: 243 QAKLPGIAKKKAE 255
>gi|41393608 reticulon 3 isoform b [Homo sapiens]
Length = 1013
Score = 244 bits (622), Expect = 1e-64
Identities = 115/189 (60%), Positives = 153/189 (80%), Gaps = 1/189 (0%)
Query: 186 VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAI 245
V DL++WRD+KKTG VFG +L +LLSL FS++SV +Y+ LALLSVTISFRIYK VIQA+
Sbjct: 825 VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAV 884
Query: 246 QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVL 305
QKS+EGHPF+AYL+ ++ +S E Y N+A+ H+N +K + RLFLV+DLVDSLK AV
Sbjct: 885 QKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVF 944
Query: 306 MWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKI 365
MW+ TYVGA+FNG+TLLILA + +FSVP++YE+++ QIDHY+G+A K + KIQAK+
Sbjct: 945 MWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKL 1004
Query: 366 PGL-KRKAE 373
PG+ K+KAE
Sbjct: 1005 PGIAKKKAE 1013
>gi|41393606 reticulon 3 isoform d [Homo sapiens]
Length = 241
Score = 215 bits (548), Expect = 5e-56
Identities = 104/181 (57%), Positives = 137/181 (75%), Gaps = 1/181 (0%)
Query: 161 PPAPAPAAPPST-PAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVS 219
P AP P PA + SS V DL++WRD+KKTG VFG +L +LLSL FS++S
Sbjct: 22 PSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVIS 81
Query: 220 VTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGH 279
V +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+ H
Sbjct: 82 VVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVH 141
Query: 280 VNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERH 339
+N +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE++
Sbjct: 142 INRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKY 201
Query: 340 Q 340
+
Sbjct: 202 K 202
>gi|46255005 reticulon 2 isoform B [Homo sapiens]
Length = 472
Score = 198 bits (503), Expect = 7e-51
Identities = 132/378 (34%), Positives = 189/378 (50%), Gaps = 37/378 (9%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGA 76
PRPQ + V EP D+ + + LE + L + P G P TAP +
Sbjct: 86 PRPQG----RSVSEPRDQHPQPSL-----GDSLESIPSLSQSPEPGRRGDP-DTAPPSER 135
Query: 77 PLMDFGN--DFVPPAPRG-------------PLPAAPPVAPERQPSWDPSP-VSSTVPAP 120
PL D D + RG PL P P R + + + +
Sbjct: 136 PLEDLRLRLDHLGWVARGTGSGEDSSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLA 195
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPP---------PPASVSPQAEPVWTPPAPAPAAPPS 171
P S ++P P P A P P P + + E W P P
Sbjct: 196 QPSSPEVLTPQLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQC 255
Query: 172 TPAAPKRRGSSGS--VVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALL 229
+ + + +V DLLYW+D + +GVVF + LL L FSIVSV A++AL LL
Sbjct: 256 LDSTDQLEFTVEPRLLVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLL 315
Query: 230 SVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRR 289
TIS R+Y+ V+QA+ + D +PF+AYL+ ++ ++ E ++ S+ V +LR
Sbjct: 316 CGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRH 375
Query: 290 LFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGL 349
FLV+DLVDSLK A+L ++ T+VGA+FNGLTLLIL +I LF++P++Y +HQAQID Y+GL
Sbjct: 376 FFLVEDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGL 435
Query: 350 ANKNVKDAMAKIQAKIPG 367
+ AKI+AKIPG
Sbjct: 436 VTNQLSHIKAKIRAKIPG 453
>gi|5032055 reticulon 2 isoform A [Homo sapiens]
Length = 545
Score = 194 bits (492), Expect = 1e-49
Identities = 133/370 (35%), Positives = 188/370 (50%), Gaps = 43/370 (11%)
Query: 31 PEDEEEEEEEEEEDEDEDLEELEVLER--KPAAGL----SAAPVPTAPAAGAPLMDFGND 84
P ++EE +E + E EEL++ R +P++ +P P AG P D
Sbjct: 167 PLEDEEPQEPNRLETGEAGEELDLRLRLAQPSSPEVLTPQLSPGSGTPQAGTPSPSRSRD 226
Query: 85 FVPPAPRGPLPAAPPVAPERQPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDE--- 138
+ GP P+ E + W P PV + V P L E
Sbjct: 227 ----SNSGP---EEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFTVEPRLLGTAMEWLK 279
Query: 139 ---PPARPPPPPPASVSPQAEPVWT----------PPAPAPAAPPSTPAAPKRRG----- 180
A P +SP P+WT PP P +P+ G
Sbjct: 280 TSLLLAVYKTVPILELSP---PLWTAIGWVQRGPTPPTPVLRVLLKWAKSPRSSGVPSLS 336
Query: 181 ---SSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRI 237
GS V DLLYW+D + +GVVF + LL L FSIVSV A++AL LL TIS R+
Sbjct: 337 LGADMGSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRV 396
Query: 238 YKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLV 297
Y+ V+QA+ + D +PF+AYL+ ++ ++ E ++ S+ V +LR FLV+DLV
Sbjct: 397 YRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLV 456
Query: 298 DSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDA 357
DSLK A+L ++ T+VGA+FNGLTLLIL +I LF++P++Y +HQAQID Y+GL +
Sbjct: 457 DSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHI 516
Query: 358 MAKIQAKIPG 367
AKI+AKIPG
Sbjct: 517 KAKIRAKIPG 526
>gi|46255007 reticulon 2 isoform C [Homo sapiens]
Length = 205
Score = 189 bits (481), Expect = 3e-48
Identities = 93/185 (50%), Positives = 130/185 (70%)
Query: 183 GSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVI 242
GS V DLLYW+D + +GVVF + LL L FSIVSV A++AL LL TIS R+Y+ V+
Sbjct: 2 GSKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVL 61
Query: 243 QAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKF 302
QA+ + D +PF+AYL+ ++ ++ E ++ S+ V +LR FLV+DLVDSLK
Sbjct: 62 QAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKL 121
Query: 303 AVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQ 362
A+L ++ T+VGA+FNGLTLLIL +I LF++P++Y +HQAQID Y+GL + AKI+
Sbjct: 122 ALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIR 181
Query: 363 AKIPG 367
AKIPG
Sbjct: 182 AKIPG 186
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 77.8 bits (190), Expect = 1e-14
Identities = 59/158 (37%), Positives = 68/158 (43%), Gaps = 26/158 (16%)
Query: 38 EEEEEEDEDEDLEE-----LEVLERKPAAGLSAAPVPT----APAA---------GAPLM 79
+EE+ ++ DL+E + L+ P AG P APAA G P
Sbjct: 1383 DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSA 1442
Query: 80 DFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEP 139
+ PP P PP AP QP P P PSP A +PS P P
Sbjct: 1443 NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP----P 1498
Query: 140 PARPPPPPPASVSPQAEPVWTPPAPAP-AAPPSTPAAP 176
P PPPPPPA SP P PPA AP AAPP PAAP
Sbjct: 1499 PPLPPPPPPAMPSPPPPP---PPAAAPLAAPPEEPAAP 1533
Score = 42.0 bits (97), Expect = 9e-04
Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 5/117 (4%)
Query: 63 LSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP--PVAPERQPSWDPSPVSSTVPAP 120
L + PT P++ G + PA GP P P P+ P P + A
Sbjct: 191 LKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLAS 250
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPV---WTPPAPAPAAPPSTPA 174
S +AAA S + A P PPPP P+ + V + PA A PP PA
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/118 (32%), Positives = 47/118 (39%), Gaps = 20/118 (16%)
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPL-----PAAPPVAPERQPSWDPSPVSS 115
A L +P P P A + P P G L P P V P P PS V S
Sbjct: 758 AFLQKSPPPPPPTAQS---------TQPTPHGLLLEAGGPDLPLVLPPPPPQLLPS-VLS 807
Query: 116 TVPAPSPLSAAA----VSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAP 169
P+PSP ++ + P+ +PP PPPPPP + Q E PAAP
Sbjct: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPP-PMPLQLEAHLRSHGLEPAAP 864
Score = 37.0 bits (84), Expect = 0.029
Identities = 18/61 (29%), Positives = 24/61 (39%)
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P P S A +P PP + P PPP +P+ PP P P AP+
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730
Query: 178 R 178
+
Sbjct: 1731 K 1731
Score = 33.5 bits (75), Expect = 0.32
Identities = 27/84 (32%), Positives = 32/84 (38%), Gaps = 15/84 (17%)
Query: 87 PPAPRGPLPAAP------PVAPERQPSWDP-SPVSSTVPAPSPLSAAAVSPSKL------ 133
P A GP P P P P R P +P P P + V+ L
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 134 PEDDEPPARPPPPPPASVSPQAEP 157
P PP PPPPPP +P +EP
Sbjct: 1034 PHQAAPPPPPPPPPPP--APASEP 1055
Score = 32.3 bits (72), Expect = 0.71
Identities = 34/125 (27%), Positives = 43/125 (34%), Gaps = 23/125 (18%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPS-PLS 124
+P P+A G L++ PA R P PP P P P P+ S L
Sbjct: 811 SPSPSASKVGVHLLE-------PATRDGAPQPPPPPPPPPP---PMPLQLEAHLRSHGLE 860
Query: 125 AAAVSPSKLPEDD-EPPAR-----------PPPPPPASVSPQAEPVWTPPAPAPAAPPST 172
AA SP PE+ +PP PP P V P P + P
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 173 PAAPK 177
AP+
Sbjct: 921 TKAPR 925
Score = 31.6 bits (70), Expect = 1.2
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
AP P++P PL +P P P PAA P+A + PSP +P PL
Sbjct: 1490 APTPSSPPP-PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHL 1548
Query: 126 A 126
A
Sbjct: 1549 A 1549
Score = 31.6 bits (70), Expect = 1.2
Identities = 30/131 (22%), Positives = 45/131 (34%), Gaps = 7/131 (5%)
Query: 52 LEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP- 110
+ V RKP PVP + A P P+ P P P PE+ S P
Sbjct: 1659 VRVCARKP---WHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPP 1715
Query: 111 --SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAA 168
+P ++ P+P + + P + ++ E R P + P
Sbjct: 1716 EQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQT-RPERSLATG 1774
Query: 169 PPSTPAAPKRR 179
P+T PK R
Sbjct: 1775 QPATSRLPKAR 1785
Score = 31.2 bits (69), Expect = 1.6
Identities = 32/121 (26%), Positives = 41/121 (33%), Gaps = 23/121 (19%)
Query: 75 GAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP-SPVSSTVPAPSPLSAAAVSPSKL 133
G D+G P P A P P P++DP P P S A
Sbjct: 956 GGAADDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPY-----CPGRASGAG------ 1002
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVW---------TPPAPAPAAPPSTPAAPKRRGSSGS 184
PE P PP + AEP+ PP P P PP PA+ + G +
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Query: 185 V 185
+
Sbjct: 1063 I 1063
Score = 30.0 bits (66), Expect = 3.5
Identities = 20/61 (32%), Positives = 23/61 (37%), Gaps = 13/61 (21%)
Query: 143 PPPPPPASVSPQAEP-------------VWTPPAPAPAAPPSTPAAPKRRGSSGSVVVDL 189
PPPPPP + S Q P + PP P P AP S+ V V L
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 190 L 190
L
Sbjct: 824 L 824
Score = 29.6 bits (65), Expect = 4.6
Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 21/87 (24%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P L + P AP +P +PP P +P+ PP P P
Sbjct: 1478 PQPALPSPPPLVAPTPSSP----PPPPLPPPPPPAMPSPPPPPP---------------P 1518
Query: 119 APSPLSAAAVSP-SKLPEDDE-PPARP 143
A +PL+A P + PED E P RP
Sbjct: 1519 AAAPLAAPPEEPAAPSPEDPELPDTRP 1545
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 67.8 bits (164), Expect = 2e-11
Identities = 70/233 (30%), Positives = 87/233 (37%), Gaps = 49/233 (21%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED---------EDEDLEEL 52
E +S + +S PP P+ A R E + EE EE+ + +E L
Sbjct: 445 ERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEIL 504
Query: 53 EVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVP-----PAPRGPLPA------APPVA 101
V P+ G AP P P G+P D P P P PLP APP A
Sbjct: 505 PVAVATPSGG--DAPTPGVPT-GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSA 561
Query: 102 PERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
P + P SP P P+P LP D PP PPPPPP + P P P
Sbjct: 562 PPQAPPLPGSPE----PPPAP---------PLPGDLPPPPPPPPPPPGTDGPVPPPP-PP 607
Query: 162 PAPAPAAPPST---------PAAPKRRGSSGSVVVDLLYWRDIKK---TGVVF 202
P P P PP P ++ + LL W +K TG VF
Sbjct: 608 PPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVF 660
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 65.1 bits (157), Expect = 1e-10
Identities = 45/129 (34%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMD-FGNDFVPPAP-RGPLPAAPPVAPERQPSWDPSPVSST 116
P +A P PT P A F ++PP+P P+P PP P++Q P S
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL 855
Query: 117 VPAPSPLSAAAVSPSKLPEDDEPPA---RPPPPPPASVSPQ------AEPVWTP---PAP 164
P PS + A S+ P PPA +P P PA+V+PQ A+P W P P P
Sbjct: 856 SPVPSVVKQIA---SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912
Query: 165 APAAPPSTP 173
+P PP P
Sbjct: 913 SPDFPPPPP 921
Score = 53.1 bits (126), Expect = 4e-07
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 20/116 (17%)
Query: 67 PVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPS--PVSSTVPAPSPLS 124
P PT PA + + P P P +PP A + +P W PS PV S P P
Sbjct: 871 PPPTPPAMESQPLK-------PVPANVAPQSPP-AVKAKPKWQPSSIPVPSPDFPPPPPE 922
Query: 125 AAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-------PAPAPAAPPSTP 173
++ V P P P PPPPPP + SP + +P +P PP TP
Sbjct: 923 SSLVFP---PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 49.7 bits (117), Expect = 4e-06
Identities = 45/144 (31%), Positives = 61/144 (42%), Gaps = 33/144 (22%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P L P PT+ AP++ PP P P+P A ++QP++ P S P
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVV---TQAAPPTPTPPVPPA-----KKQPAF---PASYIPP 826
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPAS--------VSPQAEPVWTPPA------- 163
+P P V P LP+ A+PPP P S ++ Q P TPPA
Sbjct: 827 SP-PTPPVPVPPPTLPKQQSFCAKPPPSP-LSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 164 -----PAPAAPPSTPAAPKRRGSS 182
AP +PP+ A PK + SS
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSS 908
Score = 48.9 bits (115), Expect = 7e-06
Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 21/125 (16%)
Query: 61 AGLSAAP-VPTAPAAGAP-------LMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
A L AP P+ P AP + PP P P P P+ P+ +P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ-------AP 778
Query: 113 VSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAP----APAA 168
V P+P S V+P + PP PP PPA P + PP+P P
Sbjct: 779 PKPLVTIPAPTSTKTVAP--VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 169 PPSTP 173
PP+ P
Sbjct: 837 PPTLP 841
Score = 42.0 bits (97), Expect = 9e-04
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 112 PVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPS 171
P +S VP SP V+P + P PPPPPP P P PP P+ +AP +
Sbjct: 601 PYTSLVPPLSP-QPKIVTPYTASQPSPP--LPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 172 TPAAP 176
AAP
Sbjct: 658 GSAAP 662
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 6/96 (6%)
Query: 86 VPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPP 145
+PP P P P PP P P S S+ AP + + ++ + PP
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 146 PPPA----SVSPQ--AEPVWTPPAPAPAAPPSTPAA 175
PP SV PQ P P P P PP TP +
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
PP P P P + + P P S P P + P P PPPP
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP----PTPPPPPP 768
Query: 147 PPASVSPQA--EPVWTPPAPA---PAAPPSTPAAP 176
PA + PQA +P+ T PAP AP T AAP
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 46/145 (31%)
Query: 55 LERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVS 114
++ KP S+ PVP+ DF PP P L PP PS P+P
Sbjct: 898 VKAKPKWQPSSIPVPSP------------DFPPPPPESSLVFPPP-----PPSPVPAPPP 940
Query: 115 STVPAPSPLSAAAVSP-SKLPEDDEPPARPPPPPP--------ASVSPQAEP-------- 157
P SP + SP K + P + PPP P +S + EP
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 158 --VWTPPA----------PAPAAPP 170
+TPPA P PAAPP
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPP 1025
Score = 39.3 bits (90), Expect = 0.006
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 25/109 (22%)
Query: 87 PPAPRGPLPAAPPVAPERQPS-WDPSPVS---STV----------------PAPSPLSAA 126
PP P P P PP+ + PS +P+ ST+ P P + +
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695
Query: 127 AVSPSKLPEDD----EPPARPPPPPPASVSPQAEPV-WTPPAPAPAAPP 170
+V P L + PP PPPP P S Q +P P P +APP
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP 744
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 9/95 (9%)
Query: 83 NDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPAR 142
+DF PP P LP PP+ S + SP + V P P + +S K P PP R
Sbjct: 1071 SDFPPPPPETELP-LPPIEIPAVFSGNTSPKVAVV-NPQPQQWSKMSVKKAP----PPTR 1124
Query: 143 PPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P ++ QAE + P A P P +PK
Sbjct: 1125 PKRNDSTRLT-QAE-ISEQPTMATVV-PQVPTSPK 1156
Score = 30.4 bits (67), Expect = 2.7
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 9/59 (15%)
Query: 98 PPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP-PASVSPQA 155
PP++P+ + +P +++ P+P PL P P PP PPPPP P+ +P A
Sbjct: 607 PPLSPQPKIV---TPYTASQPSP-PLPP----PPPPPPPPPPPPPPPPPPLPSQSAPSA 657
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 64.7 bits (156), Expect = 1e-10
Identities = 51/161 (31%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 31 PEDEEEEEEEEEEDEDEDLEELEV--------LERKPAAGLS-AAPVPTAPAAGAPLMDF 81
PE+ E EE E+D+++D ++ E E + G S A+ AP P
Sbjct: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
Query: 82 GNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPA 141
PP P GP P PP AP +P P P + P P P + + P +P P
Sbjct: 403 Q---APPMP-GPPPLGPPPAPPLRP---PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP 455
Query: 142 R--PPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
R PP PPP PP P P PP P P RG
Sbjct: 456 RLLPPGPPPGR----------PPGPPPGPPPGLPPGPPPRG 486
Score = 35.8 bits (81), Expect = 0.064
Identities = 35/119 (29%), Positives = 48/119 (40%), Gaps = 10/119 (8%)
Query: 39 EEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP 98
E+E D ++L +LEV + A LS A + +P AP L
Sbjct: 97 EKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDI 156
Query: 99 PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSP------SKLPEDDEPPARPPPPPPASV 151
P+ P QP PS + T P A ++ P +LP +PP PP PPP V
Sbjct: 157 PL-PGAQP---PSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQV 211
Score = 33.1 bits (74), Expect = 0.41
Identities = 39/150 (26%), Positives = 51/150 (34%), Gaps = 27/150 (18%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ--------PSWDP 110
P G P P P P G P PR P PA P + P R P P
Sbjct: 462 PPPGRPPGPPPGPPPGLPP----GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP 517
Query: 111 SPVSSTVPAPSPLSAAAVSPSKLPE----DDEPPARPPPPPPASVSPQAEPVWTPPAPAP 166
+P PAP P +P L + DD A A++S + + + P A
Sbjct: 518 APPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQ-ITNPKAEIT 576
Query: 167 AAPPS----------TPAAPKRRGSSGSVV 186
P+ AAP+R+ S V
Sbjct: 577 RFVPTALRVRRENKGATAAPQRKSEDDSAV 606
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.5 bits (153), Expect = 3e-10
Identities = 58/191 (30%), Positives = 73/191 (38%), Gaps = 28/191 (14%)
Query: 4 LDQSPLVSSSDS-PPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG 62
L SPL + S S PP P Q + P + L P +
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 63 LSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPS--------------- 107
L+ P PA P + PP+P PA+PP++P PS
Sbjct: 350 LATPPPQAPPALALPPLQ-----APPSP----PASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 108 WDPSPVSSTVPAP-SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPA-PA 165
+ P P S V AP SP ++ VSPS P PP+ PP SP A P +P A P
Sbjct: 401 FSPPP-SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 166 PAAPPSTPAAP 176
P APP A P
Sbjct: 460 PQAPPPLAAPP 470
Score = 57.4 bits (137), Expect = 2e-08
Identities = 43/136 (31%), Positives = 53/136 (38%), Gaps = 26/136 (19%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P A +P T P+ P + AP +P +PP +P PS P P +
Sbjct: 415 PPASPPVSPSATPPSQAPPSL--------AAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQA----------EPVWTPPAPAP-- 166
A PL A P P PP + P PPAS QA P+ TPP AP
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 167 ------AAPPSTPAAP 176
PPS PA+P
Sbjct: 527 LAAPLLQVPPSPPASP 542
Score = 56.2 bits (134), Expect = 5e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 25/132 (18%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP---SPVSSTVPA-- 119
A P P AP A A + PP+P P +PP +P PS P +P S P
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 120 --PSPLSAAAVSPSKLPEDDEPPARPPP--------------PPPASVSPQAEPVWTPPA 163
PSP ++ +SPS P PP PPP PPA +P + + +PPA
Sbjct: 442 VPPSPPASPPMSPSATP----PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 164 PAPAAPPSTPAA 175
P P +P+A
Sbjct: 498 SFPGQAPFSPSA 509
Score = 52.0 bits (123), Expect = 9e-07
Identities = 52/200 (26%), Positives = 71/200 (35%), Gaps = 44/200 (22%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG----------LSAA 66
PRP P+ + + P E + E E R+P+AG LS++
Sbjct: 181 PRPAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 67 PVPTAPAAGAPLMDFGNDFVPPAPRGPLPAA------PPVAPERQPSWDPSPVSSTVPAP 120
P + A + G P P P P P V P R+ + S+ P
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASV----------------SPQAEPVWTPPAP 164
+P +A SPS P P+ P PP + SP P+ TPP
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 165 AP--------AAPPSTPAAP 176
AP APPS PA+P
Sbjct: 357 APPALALPPLQAPPSPPASP 376
Score = 45.1 bits (105), Expect = 1e-04
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 36/152 (23%)
Query: 63 LSAAP--VPTAPAAGAPLMDFGNDFVPPAPRGPLP-AAPPVAPERQPSWDP----SPVSS 115
L+A P VP +P A P+ + P P+ P P AAPP+ + P P +P
Sbjct: 435 LAAPPLQVPPSPPASPPM----SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490
Query: 116 TVPAP----------SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVW----TP 161
+P+P SP ++ +SP P PP P SP A P P
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 162 PAPAP-----------AAPPSTPAAPKRRGSS 182
P P P A P P P R SS
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/149 (27%), Positives = 57/149 (38%), Gaps = 37/149 (24%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPV-APERQPSWDPSPVSST- 116
P+A L +P+ T P P++ VPP+P PA+P + AP R P+ P P +S
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPT--PGPDTSVS 560
Query: 117 --------VPAPSP------------------LSAAAVSPSKLPEDDEPP---ARPPPPP 147
P P P S+A +P +L D P A PPP
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 620
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
A ++ W+ P A P AP
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAP 649
Score = 31.2 bits (69), Expect = 1.6
Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 9/83 (10%)
Query: 50 EELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPP-----APRGPLPAAPPVAPER 104
EEL + P G +A+P P A A + PP AP PLP P P
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660
Query: 105 QPS----WDPSPVSSTVPAPSPL 123
++ S PAP L
Sbjct: 661 ADGLCTIYETEGPESATPAPGAL 683
Score = 29.3 bits (64), Expect = 6.0
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 11/106 (10%)
Query: 88 PAPRGP--LPAAPPVAPERQPSWDPSPV----SSTVPAPSPLS--AAAVSPSKLPEDDEP 139
PA R P L PP +P P P+ + ++ PL+ A + + +PE P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-AP 75
Query: 140 PARPPPP--PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSG 183
A P PPAS + P +P P + P + R G G
Sbjct: 76 RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/172 (31%), Positives = 73/172 (42%), Gaps = 38/172 (22%)
Query: 23 FKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG---LSAAPVPTAPAAGAPLM 79
F+ +F E + EEEEEEE+E+E+E+LEE+E LE A G A P PT P A
Sbjct: 931 FEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA----- 985
Query: 80 DFGNDFVPPAPRGPLPAAPPVAPE-------RQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
+PP P P P PE +P + + T P +P A S +
Sbjct: 986 ------LPP-PESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP--EALPSQGE 1036
Query: 133 LPEDDEPPARPPPP----------PPASVSPQAEPVWTPPAPAPAAPPSTPA 174
+ + E PA PPP PP + + E P PP TPA
Sbjct: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP----PPETPA 1084
Score = 52.4 bits (124), Expect = 7e-07
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 55/179 (30%)
Query: 5 DQSPLVSSSDSPPR------------PQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEEL 52
++ P+++ S +PP P+PAF + E D E E + +D + E
Sbjct: 735 NEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE- 793
Query: 53 EVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
GL P P A P P AP GP A+PPV + +P P+
Sbjct: 794 ---------GLPPLPPPPPSGATPP---------PIAPTGPPTASPPVPAKEEPEELPA- 834
Query: 113 VSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVS---PQAEPVWTPPAPAPAA 168
AP PL PP PPPP P V+ PQ P TP P A
Sbjct: 835 ------APGPLP--------------PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
Score = 40.8 bits (94), Expect = 0.002
Identities = 38/118 (32%), Positives = 45/118 (38%), Gaps = 19/118 (16%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P PT P P FG R P PA E + S V ++
Sbjct: 738 PILAPSGTPPPTIP----PDETFGG-------RVPRPAFVHYDKE-----EASDVEISLE 781
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
+ S S V P LP PP PPP ++P P +PP PA P PAAP
Sbjct: 782 SDSDDSVVIV-PEGLPPLPPPPPSGATPPP--IAPTGPPTASPPVPAKEEPEELPAAP 836
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/142 (25%), Positives = 51/142 (35%), Gaps = 11/142 (7%)
Query: 16 PPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAG 75
PP + + ++EEEEEEEEEE+E+E+ EE E E +
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE- 929
Query: 76 APLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPE 135
+F +F G L E + + + + V P
Sbjct: 930 ----EFEEEF--EEEEGELEE----EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPP 979
Query: 136 DDEPPARPPPPPPASVSPQAEP 157
PPA PPP P V P+ EP
Sbjct: 980 PTLPPALPPPESPPKVQPEPEP 1001
Score = 36.6 bits (83), Expect = 0.037
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 14/98 (14%)
Query: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARP---- 143
P+PR P PP+A Q ++ ++ S S A V+ + L PP +P
Sbjct: 590 PSPRCP----PPLACALQ-AFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPT 644
Query: 144 -----PPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
P PPP + SP P + PP P P+ A P
Sbjct: 645 CPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGP 682
Score = 33.9 bits (76), Expect = 0.24
Identities = 29/95 (30%), Positives = 33/95 (34%), Gaps = 22/95 (23%)
Query: 95 PAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP-------P 147
P PP+ P P+PV APSP A PP PP P P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPP-EAPSPFRA-------------PPFHPPGPMPSVGSMP 678
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSS 182
A P A P+ P P+A P P G S
Sbjct: 679 SAGPMPSAGPM-PSAGPVPSARPGPPTTANHLGLS 712
Score = 32.7 bits (73), Expect = 0.54
Identities = 25/100 (25%), Positives = 32/100 (32%), Gaps = 16/100 (16%)
Query: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPED---------- 136
PP P A P P PS P + +P+ P+ +A PS P
Sbjct: 653 PPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLS 712
Query: 137 -----DEPPARPPPPPPASVSPQAEPVWTPP-APAPAAPP 170
PP P P +P+ P P P PP
Sbjct: 713 VPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPP 752
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 12/162 (7%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
++P +P + RE E++ +E ++ ++ +E E ER AG S P T P
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER--GAGASGGP-STDPL 556
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPV----APERQPSWDPSPVSSTVPAPSPLS-AAAV 128
AG L D + R PAAP + AP P+ P+PV T P P P++
Sbjct: 557 AGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-PAPAPAAP 169
P P +P PPP P P P P P PA P
Sbjct: 617 QPQSAGSTSGPVPQPACPPP---GPAPHPTGPPGPIPVPAPP 655
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P P A G G+ P P PA PP P P+ P P+ P
Sbjct: 599 PVQPTSPPPGPVAQPTGPQPQSAGSTSGPV----PQPACPPPGPAPHPTGPPGPI----P 650
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P+P A S S L PPP P S +P P + P P PP AP+
Sbjct: 651 VPAP-PQIATSTSLLAAQS---LVPPPGLPGSSTPGVLPYFPPGLP----PPDAGGAPQ 701
Score = 33.9 bits (76), Expect = 0.24
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 105 QPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
QPS P P V PSP + + + P PPA PP P PA P +
Sbjct: 402 QPSLQPVASEPGCPDVEMPSPWAPSGDCAMESP----PPAPPPCPGPA---PDTIDLTLQ 454
Query: 162 PAPAPAAPPSTPAAPKRRGS 181
P P P S PA PK+ G+
Sbjct: 455 PPP----PVSEPAPPKKDGA 470
Score = 33.5 bits (75), Expect = 0.32
Identities = 41/167 (24%), Positives = 60/167 (35%), Gaps = 8/167 (4%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
D P P F + F RE E +E + ++ E + ++ S PV + P
Sbjct: 354 DDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEP- 412
Query: 74 AGAPLMDFGNDFVPPAPRGPLPA-APPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
G P ++ + P AP G +PP AP P P + T+ P P+S A
Sbjct: 413 -GCPDVEMPS---PWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKD 468
Query: 133 LPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
D A S+ + P AP A P P + R
Sbjct: 469 GAISDNTKAALKAALLKSLRSRLRD--GPSAPLEAPEPRKPVTAQER 513
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 12/162 (7%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
++P +P + RE E++ +E ++ ++ +E E ER AG S P T P
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER--GAGASGGP-STDPL 556
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPV----APERQPSWDPSPVSSTVPAPSPLS-AAAV 128
AG L D + R PAAP + AP P+ P+PV T P P P++
Sbjct: 557 AGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-PAPAPAAP 169
P P +P PPP P P P P P PA P
Sbjct: 617 QPQSAGSTSGPVPQPACPPP---GPAPHPTGPPGPIPVPAPP 655
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P P A G G+ P P PA PP P P+ P P+ P
Sbjct: 599 PVQPTSPPPGPVAQPTGPQPQSAGSTSGPV----PQPACPPPGPAPHPTGPPGPI----P 650
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P+P A S S L PPP P S +P P + P P PP AP+
Sbjct: 651 VPAP-PQIATSTSLLAAQS---LVPPPGLPGSSTPGVLPYFPPGLP----PPDAGGAPQ 701
Score = 33.9 bits (76), Expect = 0.24
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 105 QPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
QPS P P V PSP + + + P PPA PP P PA P +
Sbjct: 402 QPSLQPVASEPGCPDVEMPSPWAPSGDCAMESP----PPAPPPCPGPA---PDTIDLTLQ 454
Query: 162 PAPAPAAPPSTPAAPKRRGS 181
P P P S PA PK+ G+
Sbjct: 455 PPP----PVSEPAPPKKDGA 470
Score = 33.5 bits (75), Expect = 0.32
Identities = 41/167 (24%), Positives = 60/167 (35%), Gaps = 8/167 (4%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
D P P F + F RE E +E + ++ E + ++ S PV + P
Sbjct: 354 DDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEP- 412
Query: 74 AGAPLMDFGNDFVPPAPRGPLPA-APPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
G P ++ + P AP G +PP AP P P + T+ P P+S A
Sbjct: 413 -GCPDVEMPS---PWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKD 468
Query: 133 LPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
D A S+ + P AP A P P + R
Sbjct: 469 GAISDNTKAALKAALLKSLRSRLRD--GPSAPLEAPEPRKPVTAQER 513
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 12/162 (7%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
++P +P + RE E++ +E ++ ++ +E E ER AG S P T P
Sbjct: 500 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER--GAGASGGP-STDPL 556
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPV----APERQPSWDPSPVSSTVPAPSPLS-AAAV 128
AG L D + R PAAP + AP P+ P+PV T P P P++
Sbjct: 557 AGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 616
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-PAPAPAAP 169
P P +P PPP P P P P P PA P
Sbjct: 617 QPQSAGSTSGPVPQPACPPP---GPAPHPTGPPGPIPVPAPP 655
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P P A G G+ P P PA PP P P+ P P+ P
Sbjct: 599 PVQPTSPPPGPVAQPTGPQPQSAGSTSGPV----PQPACPPPGPAPHPTGPPGPI----P 650
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P+P A S S L PPP P S +P P + P P PP AP+
Sbjct: 651 VPAP-PQIATSTSLLAAQS---LVPPPGLPGSSTPGVLPYFPPGLP----PPDAGGAPQ 701
Score = 33.9 bits (76), Expect = 0.24
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 105 QPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
QPS P P V PSP + + + P PPA PP P PA P +
Sbjct: 402 QPSLQPVASEPGCPDVEMPSPWAPSGDCAMESP----PPAPPPCPGPA---PDTIDLTLQ 454
Query: 162 PAPAPAAPPSTPAAPKRRGS 181
P P P S PA PK+ G+
Sbjct: 455 PPP----PVSEPAPPKKDGA 470
Score = 33.5 bits (75), Expect = 0.32
Identities = 41/167 (24%), Positives = 60/167 (35%), Gaps = 8/167 (4%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
D P P F + F RE E +E + ++ E + ++ S PV + P
Sbjct: 354 DDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEP- 412
Query: 74 AGAPLMDFGNDFVPPAPRGPLPA-APPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
G P ++ + P AP G +PP AP P P + T+ P P+S A
Sbjct: 413 -GCPDVEMPS---PWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKD 468
Query: 133 LPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
D A S+ + P AP A P P + R
Sbjct: 469 GAISDNTKAALKAALLKSLRSRLRD--GPSAPLEAPEPRKPVTAQER 513
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/162 (30%), Positives = 68/162 (41%), Gaps = 12/162 (7%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
++P +P + RE E++ +E ++ ++ +E E ER AG S P T P
Sbjct: 361 EAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER--GAGASGGP-STDPL 417
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPV----APERQPSWDPSPVSSTVPAPSPLS-AAAV 128
AG L D + R PAAP + AP P+ P+PV T P P P++
Sbjct: 418 AGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGP 477
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-PAPAPAAP 169
P P +P PPP P P P P P PA P
Sbjct: 478 QPQSAGSTSGPVPQPACPPP---GPAPHPTGPPGPIPVPAPP 516
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P P A G G+ P P PA PP P P+ P P+ P
Sbjct: 460 PVQPTSPPPGPVAQPTGPQPQSAGSTSGPV----PQPACPPPGPAPHPTGPPGPI----P 511
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P+P A S S L PPP P S +P P + P P PP AP+
Sbjct: 512 VPAP-PQIATSTSLLAAQS---LVPPPGLPGSSTPGVLPYFPPGLP----PPDAGGAPQ 562
Score = 33.9 bits (76), Expect = 0.24
Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 14/80 (17%)
Query: 105 QPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
QPS P P V PSP + + + P PPA PP P PA P +
Sbjct: 263 QPSLQPVASEPGCPDVEMPSPWAPSGDCAMESP----PPAPPPCPGPA---PDTIDLTLQ 315
Query: 162 PAPAPAAPPSTPAAPKRRGS 181
P P P S PA PK+ G+
Sbjct: 316 PPP----PVSEPAPPKKDGA 331
Score = 33.5 bits (75), Expect = 0.32
Identities = 41/167 (24%), Positives = 60/167 (35%), Gaps = 8/167 (4%)
Query: 14 DSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA 73
D P P F + F RE E +E + ++ E + ++ S PV + P
Sbjct: 215 DDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEP- 273
Query: 74 AGAPLMDFGNDFVPPAPRGPLPA-APPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
G P ++ + P AP G +PP AP P P + T+ P P+S A
Sbjct: 274 -GCPDVEMPS---PWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKD 329
Query: 133 LPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
D A S+ + P AP A P P + R
Sbjct: 330 GAISDNTKAALKAALLKSLRSRLRD--GPSAPLEAPEPRKPVTAQER 374
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%)
Query: 39 EEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP 98
E + +D ++EEL +P++ P++ +P P GP+P+ P
Sbjct: 1007 EGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQS------PTISEGPVPSLP 1060
Query: 99 PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPV 158
+ P R PS P P S+ +P A P K P P RPPPP P + + P
Sbjct: 1061 -IRPSRAPSRTPGPPSAQ-SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP 1118
Query: 159 WTPPAPAPAAPPSTPAAPKRRGSSG 183
PP P+ + PS A G +G
Sbjct: 1119 QRPPPPSGRSQPSPQAGLAGPGPAG 1143
Score = 31.6 bits (70), Expect = 1.2
Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 5/68 (7%)
Query: 62 GLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPS 121
G + P P P A P + PPA R P P AP P P P T P P
Sbjct: 1186 GSTFLPEPLKPQAAFPPQ---SSLPPPAQRLQEPLVPVAAP--MPQSGPQPNLETPPQPP 1240
Query: 122 PLSAAAVS 129
P S ++ S
Sbjct: 1241 PRSRSSHS 1248
Score = 30.8 bits (68), Expect = 2.1
Identities = 26/103 (25%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P AG+ +AP A A+ L +G P+ P+ P S++P
Sbjct: 1153 PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA-----FPPQSSLP 1207
Query: 119 APSPLSAAAVSPSKLPEDDEPPA----RPPPPPPASVSPQAEP 157
P+ + P P P PP PPP S S + P
Sbjct: 1208 PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1250
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 60.8 bits (146), Expect = 2e-09
Identities = 54/202 (26%), Positives = 74/202 (36%), Gaps = 53/202 (26%)
Query: 1 MEDLDQSPLVSSSDS-----------PPRPQP-------------AFKYQFVREPEDEEE 36
+ED+ +PL S + PP P P A R P E+
Sbjct: 569 LEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKM 628
Query: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAA--PVPTAPAAGAPLMDFGNDFVPPAPRGPL 94
+E ++ ED ++ + E+ P+A +++A P P GA + + P P P
Sbjct: 629 DEGQQSSGEDMEISDDEM----PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684
Query: 95 PAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQ 154
P PP+ P P P P P PL P PPPPPPA +
Sbjct: 685 PGFPPLPPPPPPP----PPQPGFPMPPPL----------------PPPPPPPPPAHPAVT 724
Query: 155 AEPVWTPPAPAPAAPPSTPAAP 176
P PP PAP P P P
Sbjct: 725 VPP---PPLPAPPGVPPPPILP 743
Score = 60.8 bits (146), Expect = 2e-09
Identities = 69/219 (31%), Positives = 85/219 (38%), Gaps = 58/219 (26%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEE---EEEEEEEDEDEDLEELEVLERK 58
E + S SSS+S P EDEEE EEEEEE+E+E + E +
Sbjct: 1114 ESSESSEFESSSESSPSSS-----------EDEEEVVAREEEEEEEEEEMVAEESMASAG 1162
Query: 59 PAA----GLSAAPVPTAPAAGAPLM----DFGNDFVPPAPRGPLPAAPPV-------APE 103
P G AA P APA + M D + V P R + PP+ A
Sbjct: 1163 PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADS 1222
Query: 104 RQPSWDPSP-------VSSTVPAPSPLSAAAVSPSKLPEDD-----EPPAR--------- 142
R+P +P +S PA + +SP + PE D EPP
Sbjct: 1223 REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPL 1282
Query: 143 PPPPPPASVSPQAEPVWT-------PPAP-APAAPPSTP 173
PPP PP SP EP T PP P A PP TP
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 12/127 (9%)
Query: 72 PAAGAPLMDFGNDFVP---PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAV 128
PA P F + F P P P P P A + D S PAP PL A
Sbjct: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARD-SGEFRRAPAPPPLPPA-- 440
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPV--WTP-PAPAPAAP--PSTPAAPKRRGSSG 183
P + PP PPPP S+ P W+P P +P P S+PA P++ S
Sbjct: 441 EPLAKEKPGTPPG-PPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSL 499
Query: 184 SVVVDLL 190
+++L
Sbjct: 500 DSRIEML 506
Score = 36.6 bits (83), Expect = 0.037
Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 93 PLPAAPPVAPERQPSWDP--SPVSSTVPAPS-PLSAAAVSPSKLPEDDEPPARPPPPPPA 149
P PA AP + ++ P +PV+ P P P + AA E PA PPP PPA
Sbjct: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPA-PPPLPPA 440
Query: 150 SVSPQAEPVWTPPAPAP 166
+ +P TPP P P
Sbjct: 441 EPLAKEKP-GTPPGPPP 456
Score = 36.2 bits (82), Expect = 0.049
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 24/96 (25%)
Query: 75 GAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSW-DPSPVSSTVPAPSPLSAAAVSPSKL 133
G+P+ + P AP G QP + P+P SS PS +SP+ L
Sbjct: 530 GSPISSSSSQLSPLAPFGT---------NSQPGFRGPTPPSSR---PSSTGLEDISPTPL 577
Query: 134 PEDDE-----------PPARPPPPPPASVSPQAEPV 158
P+ DE PP P PP PA + Q V
Sbjct: 578 PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEV 613
Score = 35.0 bits (79), Expect = 0.11
Identities = 44/152 (28%), Positives = 50/152 (32%), Gaps = 19/152 (12%)
Query: 66 APVPTAPAAGAPLMDFGNDF----VPPAPRGPL--PAAPPVAPERQPSWDP--SPVSSTV 117
AP P+ + G P G DF P GPL P P R P SPV
Sbjct: 1369 APSPSLSSGGLPRTP-GRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLET 1427
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P PL P LP AR P P P + PAP + PP P
Sbjct: 1428 GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLL----------PAPLASCPPPMKRKPG 1477
Query: 178 RRGSSGSVVVDLLYWRDIKKTGVVFGASLFLL 209
R S ++ L G G L LL
Sbjct: 1478 RPRRSPPSMLSLDGPLVRPPAGAALGRELLLL 1509
Score = 34.7 bits (78), Expect = 0.14
Identities = 47/176 (26%), Positives = 67/176 (38%), Gaps = 14/176 (7%)
Query: 11 SSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDED--EDLEELEVLERKPAAGLSAAPV 68
S S QP Y F ++P + E + D E + PA ++A
Sbjct: 284 SQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPA--VTAVAG 341
Query: 69 PTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAV 128
TA G+ + FG GP A P + P P +T P+P +A
Sbjct: 342 ATAAFRGSSDLPFGAVGGTGGSSGPPFKAQP-QDSATFAHTPPPAQAT---PAPGFKSAF 397
Query: 129 SPSKLPEDDEPPARPPPPPPASVSPQAEPVWT---PPAPAPAAPPSTPAAPKRRGS 181
SP + P PP PP P A+ + A PAP P PP+ P A ++ G+
Sbjct: 398 SPYQTPVAHFPP--PPEEPTATAAFGARDSGEFRRAPAPPPL-PPAEPLAKEKPGT 450
Score = 34.3 bits (77), Expect = 0.19
Identities = 14/27 (51%), Positives = 21/27 (77%)
Query: 30 EPEDEEEEEEEEEEDEDEDLEELEVLE 56
E E+E EEEEEEE+D+D+D ++ + E
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESE 1075
Score = 32.0 bits (71), Expect = 0.92
Identities = 13/20 (65%), Positives = 17/20 (85%)
Query: 29 REPEDEEEEEEEEEEDEDED 48
+E +EEEE EEEEE+ED+D
Sbjct: 1045 QESTEEEEEAEEEEEEEDDD 1064
Score = 32.0 bits (71), Expect = 0.92
Identities = 39/142 (27%), Positives = 43/142 (30%), Gaps = 40/142 (28%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
AP P P APL PP R P P R P PS +S P P +
Sbjct: 1453 APTPLPPLLPAPLASCP----PPMKR------KPGRPRRSP---PSMLSLDGPLVRPPAG 1499
Query: 126 AAVSPSKL-----------PEDDEP----------------PARPPPPPPASVSPQAEPV 158
AA+ L P +P P PP PPP P EP
Sbjct: 1500 AALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPT 1559
Query: 159 WTPPAPAPAAPPSTPAAPKRRG 180
P PS P RG
Sbjct: 1560 KLPFKELDNQWPSEAIPPGPRG 1581
Score = 30.8 bits (68), Expect = 2.1
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 24 KYQFVREPEDEEEEEEEEEEDEDED 48
K E E EEEEE EEE+E+ED
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEED 1062
Score = 30.4 bits (67), Expect = 2.7
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 9 LVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDED--EDLEELE 53
L S + + + + + E E+ EEEEEEE++D+D +D +E E
Sbjct: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESE 1075
Score = 28.9 bits (63), Expect = 7.8
Identities = 42/190 (22%), Positives = 58/190 (30%), Gaps = 33/190 (17%)
Query: 24 KYQFVREPEDEEEEEEEEE--EDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDF 81
K F+REP+ + E + E L L G P++ + L D
Sbjct: 513 KLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDI 572
Query: 82 GNDFVPPAPR--------GPLPAAPPVAPERQPSWDPSP------VSSTVPAPSPLSAAA 127
+P + GP P P P+ + V P +
Sbjct: 573 SPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQ 632
Query: 128 VSPSKLPE--DDEPPARPPP----PPPASVSPQAEPVWTP-----------PAPAPAAPP 170
S + E DDE P+ P P P V+P A V P P P PP
Sbjct: 633 QSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPP 692
Query: 171 STPAAPKRRG 180
P P + G
Sbjct: 693 PPPPPPPQPG 702
Score = 28.9 bits (63), Expect = 7.8
Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 45/196 (22%)
Query: 4 LDQSPLVSSSD--SPPRP-----QPAFKYQFVREPEDEEEEEEE------EEEDEDEDLE 50
++ SP+ SSS SP P QP F+ E+ + DEDE+L+
Sbjct: 528 MEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELD 587
Query: 51 ELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPR---GPLPAAPP--VAPERQ 105
L + R P P +D D P + + G + ++ +
Sbjct: 588 -LGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM 646
Query: 106 PSWDPSPVSST-VPAP---SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
PS +P++S P P +P +AA +PS L P P PPPP P
Sbjct: 647 PS---APITSADCPKPMVVTPGAAAVAAPSVLA-----PTLPLPPPPGF----------P 688
Query: 162 PAPAPAAPPSTPAAPK 177
P P PP P P+
Sbjct: 689 PLP----PPPPPPPPQ 700
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 60.8 bits (146), Expect = 2e-09
Identities = 43/130 (33%), Positives = 53/130 (40%), Gaps = 28/130 (21%)
Query: 62 GLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP--- 118
G+ A+P P GAP PPA P P P P P W P+P ++T P
Sbjct: 929 GIPASPSPK----GAP--------TPPAATPPSPKGGPATPS--PKWAPTPPAATPPSPK 974
Query: 119 ----------APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP-PAPAPA 167
AP+P +A SP P P P PP SP+ P TP P A
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 168 APPSTPAAPK 177
P +TP +PK
Sbjct: 1035 PPAATPPSPK 1044
Score = 59.7 bits (143), Expect = 4e-09
Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 25/142 (17%)
Query: 59 PAAGL---SAAPVPTAPAAGAPLMDFGNDFVPPAPRGP--LPAAPPVAPERQPSWDP--- 110
P GL S PT PAA P G P+P+G PAA P +P+ P+ P
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262
Query: 111 --SPVSSTVP-------------APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQA 155
+P ++T P AP+P SP P P P PP SP+
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 156 EPVWTPPAPAPAAPPSTPAAPK 177
P PP AP P TP +PK
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPK 1344
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/179 (31%), Positives = 75/179 (41%), Gaps = 23/179 (12%)
Query: 7 SPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAA 66
SP + S +PP P+ A V P + +E + L + PA
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVT-PLSPKGVTLPPKETPTPSVVNLPFPKEGPAT----- 902
Query: 67 PVPT-APAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
P P APA PAP+G +PA+P P P+P ++T P+P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKG-IPASP------SPKGAPTPPAATPPSPKG-GP 954
Query: 126 AAVSPSKLPEDDEPPARPPPPP---PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGS 181
A SP P PPA PP P PA+ SP+ P TPPA P +P PA P +G+
Sbjct: 955 ATPSPKWAPT---PPAATPPSPKGGPATPSPKGAP--TPPAATPPSPKGGPATPSPKGA 1008
Score = 58.2 bits (139), Expect = 1e-08
Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 69 PTAPAAGAPLMDFGNDFVPPAPRGPL--PAAPPVAPERQPSWDPSPVSSTVPA----PSP 122
PT PAA P G P+P+G PA P +P+ P+ P P ++ P PSP
Sbjct: 986 PTPPAATPPSPKGGP--ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 123 LSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGS 181
+ A +P P A P P +P + TPPA P +P PA P +G+
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Score = 57.0 bits (136), Expect = 3e-08
Identities = 44/140 (31%), Positives = 56/140 (40%), Gaps = 21/140 (15%)
Query: 59 PAAGLSAAP---VPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSS 115
P GL+ P PT PAA P G PP PAA P +P+ + P +
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 116 TVPAPSPLS--AAAVSPSKLPEDDEPPARPPPPPPASVSPQAE-----PVWTPPAP---- 164
T PA +P S +PS P A PP P +P + P TPP+P
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232
Query: 165 -------APAAPPSTPAAPK 177
AP P +TP +PK
Sbjct: 1233 ATPSPKGAPTTPAATPPSPK 1252
Score = 56.6 bits (135), Expect = 3e-08
Identities = 44/137 (32%), Positives = 57/137 (41%), Gaps = 11/137 (8%)
Query: 59 PAAGLSAAP---VPTAPAAGAPLMDFGNDFVPPAPRGP--LPAAPPVAPE---RQPSWDP 110
P GL+ P PT PAA P G P+P+G PAA P +P+ PS
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGG--LATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
Query: 111 SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPP 170
+P + PSP A +PS P A PP P +P + TPPA P +
Sbjct: 1217 APTTPAATPPSPKGGLA-TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 171 STPAAPKRRGSSGSVVV 187
A P +G+ VV
Sbjct: 1276 GGLATPPHKGAPNPAVV 1292
Score = 56.6 bits (135), Expect = 3e-08
Identities = 47/133 (35%), Positives = 54/133 (40%), Gaps = 13/133 (9%)
Query: 59 PAAGL---SAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPE---RQPSWDPSP 112
P GL S PT PAA P G PP PAA P + + P +P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP 1287
Query: 113 VSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP---PASVSPQAEPVWTPPAPAPAAP 169
+ V PSP A SP K PPA PP P P + P+ P TPPA P +P
Sbjct: 1288 NPAVVTPPSPKGGPATSPPK--GAPTPPAATPPSPKGSPGTPPPKGAP--TPPAVTPPSP 1343
Query: 170 PSTPAAPKRRGSS 182
TP P SS
Sbjct: 1344 KGTPTLPATTPSS 1356
Score = 55.8 bits (133), Expect = 6e-08
Identities = 46/122 (37%), Positives = 59/122 (48%), Gaps = 14/122 (11%)
Query: 69 PTAPAAGAPLMDFGNDFVPPAPRGPL--PAAPPVAPERQPSWDPSPVSS-TVPA---PSP 122
PT PA P G+ P P+G PAA P +P+ P+ P P + T PA PSP
Sbjct: 1009 PTPPAVTPPSPK-GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 123 LSAAAVSPSKLPEDDEPPARPPPPP---PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
A +PS L PPA PP P PA+ SP+ P+ PPA P +P A P +
Sbjct: 1068 KGGPA-TPS-LKGAPTPPAATPPSPKGGPATPSPKGAPM--PPAATPPSPKGGLATPPHK 1123
Query: 180 GS 181
G+
Sbjct: 1124 GA 1125
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/139 (31%), Positives = 54/139 (38%), Gaps = 22/139 (15%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDF-------VPPAPRGPLPAAPPVAPERQPSWDPS 111
PAA PT PAA P G PPA P P P P P P
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS--PKGAPM 1104
Query: 112 PVSSTVPAP-----------SPLSAAAVSPSKLPEDDEPPARPPPPPPASV--SPQAEPV 158
P ++T P+P +P + AA PS PP + P PA+ SP+
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 159 WTPPAPAPAAPPSTPAAPK 177
PP AP P +TP +PK
Sbjct: 1165 TPPPKGAPTTPAATPPSPK 1183
Score = 52.4 bits (124), Expect = 7e-07
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 23/142 (16%)
Query: 59 PAAGLSAAPVP---TAPAAGAPLMDFGNDFVPPAPRGP--LPAAPPVAPERQPSWD---- 109
P +A P P + P A P G+ P P+G PAA +P+ P+
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 110 -PSPVSSTVPAP-----------SPLSAAAVSPSKLPEDDEPPARPPPPPPASV--SPQA 155
P+P ++T P+P +P+ AA PS PP + P PA+ SP+
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 156 EPVWTPPAPAPAAPPSTPAAPK 177
PP AP P +TP +PK
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPK 1160
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/114 (34%), Positives = 46/114 (40%), Gaps = 21/114 (18%)
Query: 70 TAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVS-STVPAPSPLSAAAV 128
T P GAP PPA P P P P PS P + S+ P+P
Sbjct: 1326 TPPPKGAP--------TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP------ 1371
Query: 129 SPSKLPEDDEPPARPPPPP---PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRR 179
P+ P PA PP P PA SP+ +P T PA P +P PA P R
Sbjct: 1372 -PAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--TSPAVIPLSPKKAPATPVTR 1422
Score = 50.8 bits (120), Expect = 2e-06
Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
Query: 69 PTAPAA-GAPLMDFGNDFVPPAPRGPLPAAP----PVAPERQPSWDPSPVSSTVPAPSPL 123
P P+ GAP+ PP+P+G L P P P P +++ P +P
Sbjct: 1094 PATPSPKGAPMPPAAT---PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150
Query: 124 SAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAP--APAAPPSTPAAPK 177
+ AA PS PP + P PA+ P + P+P AP P +TP +PK
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/164 (28%), Positives = 62/164 (37%), Gaps = 44/164 (26%)
Query: 59 PAAGLSAAP---VPTAPAAGAPLMDFG----------NDFV--PPAPRG----------- 92
P G + P PT PAA P + G N V PP+P+G
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 93 PLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVS--PSKLPEDDEPPARP-----PP 145
PAA P +P+ P P + T PA +P S P+ P P P P
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
Query: 146 PPPASVSPQAEPVWTPPAPA-----------PAAPPSTPAAPKR 178
PP A+ S + P TPP+P P +P P +PK+
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Score = 49.3 bits (116), Expect = 6e-06
Identities = 43/138 (31%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 57 RKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPV--APERQPSWDPSPVS 114
R P A + PA AP +PPA P P P P+ P+ S +
Sbjct: 1524 RDPIAPTATLLSKKTPATLAPK----EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
Query: 115 STVPAPSPLS-AAAVSPSKL---PEDDEPPARPPPPPPASVSPQAEPVWTPPAP--APAA 168
S+ PA +P + A SP +L P P + P PPA P E PAP P +
Sbjct: 1580 SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS 1639
Query: 169 PPSTPAAPKRRGSSGSVV 186
PP TP++ K +S + V
Sbjct: 1640 PPVTPSSLKDSPTSPASV 1657
Score = 48.9 bits (115), Expect = 7e-06
Identities = 44/139 (31%), Positives = 53/139 (38%), Gaps = 24/139 (17%)
Query: 62 GLSAAPVPTA---PAAGAPLMDFGNDFVPPAPRGPL-PAAPPVAPERQPSWDPSPVSSTV 117
G A P P P A P G PP P PAA P +P+ + P + T
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 118 PA---PSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAE-----PVWTPPAP----- 164
PA PSP A P K P A PP P +P + P TPP+P
Sbjct: 1152 PAATPPSPKGGLATPPPK-GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 165 ------APAAPPSTPAAPK 177
AP P +TP +PK
Sbjct: 1211 TPSPKGAPTTPAATPPSPK 1229
Score = 48.9 bits (115), Expect = 7e-06
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 35/140 (25%)
Query: 69 PTAPAAGAPLMDFGNDFVPPAP-RGPL----------PAAPPVAPERQPSWD-------- 109
PT PAA P G PP+P RGP PA P++P++ P+
Sbjct: 1369 PTPPAA-TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 110 PSPVSSTVPAPSPLS-----------AAAVSPSKLPEDDEPPARPP----PPPPASVSPQ 154
PS T PA +P+S +PS + P PP PP P V+
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 155 AEPVWTPPAPAPAAPPSTPA 174
+ P P PAP P+ PA
Sbjct: 1488 SSPKKAPATPAPMGAPTLPA 1507
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 10/124 (8%)
Query: 62 GLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPL----PAAPPVAPERQPSWDPSPVSSTV 117
G P T + G P + P P PA P +P+R P+ T
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQA-EPVWTPPAPAPAAPPSTPAAP 176
PA PLS P K P P ++P A PV APA +AP PA P
Sbjct: 1405 PAVIPLS-----PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 177 KRRG 180
+G
Sbjct: 1460 SSKG 1463
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 8/121 (6%)
Query: 63 LSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSP 122
L AP +AP G D PA P P PP + S P +T P+P
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT---PAP 1499
Query: 123 LSA---AAVSPSKLPEDDEPPA--RPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
+ A AV PS E P+ R P P A++ + P P A P T +PK
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 178 R 178
+
Sbjct: 1560 K 1560
Score = 38.1 bits (87), Expect = 0.013
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 14/123 (11%)
Query: 58 KPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSST- 116
+P A + P+ +A + A L G PP P A + P PS ++ST
Sbjct: 18 QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTP 77
Query: 117 --VPAPS-------PLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPV--WTPPAPA 165
VP P PL A +P+ LP PP P A SP P TP + A
Sbjct: 78 LEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI--SPAALALASPMIAPTLKGTPSSSA 135
Query: 166 PAA 168
P A
Sbjct: 136 PLA 138
Score = 38.1 bits (87), Expect = 0.013
Identities = 46/175 (26%), Positives = 55/175 (31%), Gaps = 55/175 (31%)
Query: 63 LSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPS------------WDP 110
L A P+ AP + AP P P P P PS DP
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 111 ----------------------SPVSSTVPA-------PSPLSAAAVSPSKLPEDDEPPA 141
P + TVP+ P+P A A SK E PPA
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK--EASSPPA 1584
Query: 142 RPPPP------------PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGS 184
P PPA SP + TPPA P +P PA P +G+ S
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS 1639
Score = 33.5 bits (75), Expect = 0.32
Identities = 30/90 (33%), Positives = 40/90 (44%), Gaps = 13/90 (14%)
Query: 110 PSPVSSTVPA-----PSPLSAAAVSP-SKLPEDDEPPARPPP--PPPASVSPQAEPV--- 158
P + TVPA P P + AV P S +P P PPP S +PQ P+
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 159 -WTPPAPAPAAPPSTP-AAPKRRGSSGSVV 186
P P+P+ STP P + SSG+ +
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTAL 91
Score = 33.1 bits (74), Expect = 0.41
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 16/113 (14%)
Query: 87 PPAPRGPLPAAPPV--APERQPSWDPSPVSSTVPAP-SPLSAAAVSPSKLPEDDEP-PAR 142
PPA P P P AP+ P+ P SS +P SP S + +P+ + PA+
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 143 PPPPPPASV----SPQAEPVWTPPA--------PAPAAPPSTPAAPKRRGSSG 183
P V +P++ P+ T P + +PP P + GS G
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Score = 33.1 bits (74), Expect = 0.41
Identities = 35/120 (29%), Positives = 45/120 (37%), Gaps = 34/120 (28%)
Query: 69 PTAPAAGAPLMDFGNDFVPPA--------PRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
P + A APL+ D A P+GPL APP + A
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL--APPESK----------------AS 1770
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
+PL+AAA LP+ + P PP S+ P A P+P P PP P G
Sbjct: 1771 TPLTAAAFE-KVLPKPESASVSAAPSPPVSL-PLA------PSPVPTLPPKQQFLPSSPG 1822
Score = 32.3 bits (72), Expect = 0.71
Identities = 40/148 (27%), Positives = 54/148 (36%), Gaps = 39/148 (26%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLS 124
+ P P+ P AG P G V A +P+ P+ D S S+T + L+
Sbjct: 733 SVPSPSLPPAGTPP---GTKKVDGISHTSALAPVASSPKECPTED-SGASATASSKGTLT 788
Query: 125 AAAVSPSKL-----PEDDEPPARP----PPPPPASVSPQAEPVW---------------- 159
A SPS L P+ PP + P P ++S PV
Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
Query: 160 --------TPPAPAPAAPPS--TPAAPK 177
TPP+P A PS TP +PK
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Score = 29.3 bits (64), Expect = 6.0
Identities = 31/119 (26%), Positives = 43/119 (36%), Gaps = 4/119 (3%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG--PLPAAPPVAPERQPSWDPSPVSST 116
PAA A+P+ G P V AP A PP PS + S
Sbjct: 113 PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV 172
Query: 117 VPAPSPL--SAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTP 173
+ +P+ S + +K+P + P + P PP VS TP A + S P
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLP 231
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 60.5 bits (145), Expect = 2e-09
Identities = 44/115 (38%), Positives = 46/115 (40%), Gaps = 21/115 (18%)
Query: 64 SAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPL 123
S P P A GAP PP P AAPP P PS S VP P P
Sbjct: 297 SGPPPPPARGRGAP---------PPPPSRAPTAAPPPPP-------PSRPSVAVPPPPPN 340
Query: 124 SAAAVSPSKLPEDDEPPARPPPPPPA--SVSPQAEPVWTPPAPAPAAPPSTPAAP 176
P LP P+ PPPPPP+ V P A P PP P P PP P P
Sbjct: 341 RMYPPPPPALP--SSAPSGPPPPPPSVLGVGPVAPPP-PPPPPPPPGPPPPPGLP 392
Score = 58.9 bits (141), Expect = 7e-09
Identities = 48/133 (36%), Positives = 52/133 (39%), Gaps = 28/133 (21%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPR--GPLP------AAPPVAPERQPSWDPSPV---- 113
AP P P+ G P PP P GP P APP P R P+ P P
Sbjct: 276 APPPPPPSRGGPPPP------PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSR 329
Query: 114 -SSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA--SVSPQAEPVWTPPAPAPAAPP 170
S VP P P P LP P+ PPPPPP+ V P A PP P P PP
Sbjct: 330 PSVAVPPPPPNRMYPPPPPALPSS--APSGPPPPPPSVLGVGPVA-----PPPPPPPPPP 382
Query: 171 STPAAPKRRGSSG 183
P P S G
Sbjct: 383 PGPPPPPGLPSDG 395
Score = 28.9 bits (63), Expect = 7.8
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 143 PPPPPPASVSPQAEPVW---TPPAPAPAAPPSTPAAPKRRGSSGS 184
PPPPPP+ P P + P P PA P P R + +
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAA 321
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 60.5 bits (145), Expect = 2e-09
Identities = 51/147 (34%), Positives = 62/147 (42%), Gaps = 39/147 (26%)
Query: 59 PAAGLSAAPVPTAPA--AGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSST 116
P SA P P AP A PL VPP+P PA+PP++P P P+ +
Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQ------VPPSP----PASPPMSPSATPPPRVPPLLAA 763
Query: 117 VPA---PSPLSAAAVSPSKLPEDDEPPARPPPP------PPASVSPQA----------EP 157
P PSP ++ +SP P PPA PP PPAS QA P
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 158 VWTPPAPAP--------AAPPSTPAAP 176
+ TPP AP PPS PA+P
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASP 850
Score = 60.1 bits (144), Expect = 3e-09
Identities = 45/117 (38%), Positives = 59/117 (50%), Gaps = 17/117 (14%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLS 124
A P P AP A A + AP P P+ P AP P+ P S+T P+ +P S
Sbjct: 646 ATPSPQAPNALAV-------HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 125 AAAVSPSKLPEDDEPPARPPPPPPASVSPQAEP------VWTPPAPAPAAPPSTPAA 175
AA P ++P PPA PP P A+ PQA P + PP+P PA+PP +P+A
Sbjct: 699 LAA-PPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-PASPPMSPSA 751
Score = 58.9 bits (141), Expect = 7e-09
Identities = 44/129 (34%), Positives = 60/129 (46%), Gaps = 17/129 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQP--------SWDP 110
P A +P T P+ P + VPP+P PA+PP++P P + P
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAPPPLAAPP 734
Query: 111 SPVSSTVPAPSPLSAAAVSPSKLPE-DDEPPARPPPPPPAS--VSPQAEPVWTPPAPAPA 167
V + PA P+S +A P ++P PP + PP PPAS +SP A+P P AP
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP--PPQAPPAL 792
Query: 168 APPSTPAAP 176
A P A P
Sbjct: 793 ATPPLQALP 801
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 25/132 (18%)
Query: 65 AAPVPTAPAAGA--PLMDFGNDFVPPAPRGPLPAAPPVAP--------ERQPSWDPSPVS 114
A P P AP A A PL +P P PL PP AP + PS SP
Sbjct: 588 ATPPPQAPPALASPPLQG-----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 115 STVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPAS--VSPQAEPVWTPPAPAPAA---- 168
S + PSP + A++ L PP PP P S SP P TPP+ AP +
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 169 ----PPSTPAAP 176
PPS PA+P
Sbjct: 703 PLQVPPSPPASP 714
Score = 54.7 bits (130), Expect = 1e-07
Identities = 45/132 (34%), Positives = 62/132 (46%), Gaps = 20/132 (15%)
Query: 55 LERKPAAGLSA---APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPS 111
L P GL + +P+ T P P + PP+P PA+PP++P PS +
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPS-PQA 652
Query: 112 PVSSTV--------PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPA 163
P + V P PSP A SP P P A PP P S++ A P+ PP+
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLA--APPLQVPPS 709
Query: 164 PAPAAPPSTPAA 175
P PA+PP +P+A
Sbjct: 710 P-PASPPMSPSA 720
Score = 53.9 bits (128), Expect = 2e-07
Identities = 51/176 (28%), Positives = 66/176 (37%), Gaps = 29/176 (16%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG----------LSAA 66
PRP P+ + + P E + E E R+P+AG LS++
Sbjct: 190 PRPAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 67 PVP-TAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
P ++PA P P AP P P +P P PA PLS+
Sbjct: 246 ATPLSSPARSGP----SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 126 AAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPA-----PAAPPSTPAAP 176
SP P ARP PPP + +P P PP+P P APPS A P
Sbjct: 302 ---SPLATPSPSGTKARPVPPPDNAATPL--PATLPPSPPLATPLPLAPPSPSAPP 352
Score = 52.4 bits (124), Expect = 7e-07
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 14/141 (9%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFV-------PPAPRGPLPAAPPVAPERQPSWDPS 111
P A L+ P+ P+ P + + + PP P P P P +P P P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPSPLTTP---PP 581
Query: 112 PVSSTVPAPSPLSAAAVSPSKLPEDDEPPARP--PPPPPASVSPQAEPVWTPPAPAPAAP 169
S++ P P + A++ L PP P PPP A P+ PP+P PA+P
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP-PASP 640
Query: 170 PSTPAAPKRRGSSGSVVVDLL 190
P +P A + ++ V LL
Sbjct: 641 PLSPLATPSPQAPNALAVHLL 661
Score = 52.0 bits (123), Expect = 9e-07
Identities = 47/149 (31%), Positives = 58/149 (38%), Gaps = 21/149 (14%)
Query: 49 LEELEVLERKP----AAGLSAAPVPTAPA-AGAPLMDFGNDFVPPAPRGPL------PAA 97
LE L L P +A L+ + T P A PL + P P P P A
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 98 PPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQA-- 155
PP PSP S + P P + ++ L PPA PP P A+ SPQA
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 156 --------EPVWTPPAPAPAAPPSTPAAP 176
P PP+P AP S PA+P
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 47.4 bits (111), Expect = 2e-05
Identities = 43/150 (28%), Positives = 53/150 (35%), Gaps = 26/150 (17%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ-PSWDPSPVSSTV 117
P A +P T P PL+ VPP+P LP +P P Q P +P +
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 118 PAP----------SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVW----TPPA 163
P+P SP ++ +SP P PP P SP A P PP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 164 PAP-----------AAPPSTPAAPKRRGSS 182
P P A P P P R SS
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
Score = 46.6 bits (109), Expect = 4e-05
Identities = 44/146 (30%), Positives = 59/146 (40%), Gaps = 35/146 (23%)
Query: 65 AAPVPTAPAAGA--PLMDFGNDFVPPAPRGPLPAAPPVAP-ERQPSWDPSPVSS------ 115
A+ P AP + P ++ + PP+ + P PA+ P E PS P P+ +
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTP-PASLTTPPLENLPSLAPPPLQTASAPLT 554
Query: 116 -----TVPAPSPLSAAA----------VSPSKL--PEDDEPPARPPPPPPASVSPQAEPV 158
T P P+P A +PS + P PPA PP SP P+
Sbjct: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 159 WTPPAPAP--------AAPPSTPAAP 176
TPP AP APPS PA+P
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASP 640
Score = 45.4 bits (106), Expect = 8e-05
Identities = 46/175 (26%), Positives = 62/175 (35%), Gaps = 50/175 (28%)
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAP--RGPLPAAPPV-----------APERQPS 107
+G A PVP A PL +PP+P PLP APP +P P
Sbjct: 310 SGTKARPVPPPDNAATPLPAT----LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365
Query: 108 WDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPP------------------- 148
P +T P +P S + P ++P P+ PP P
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
Query: 149 -------------ASVSPQAEPVWTPP-APAPAAPPSTPAAPKRRGSSGSVVVDL 189
AS++ + P TPP +P AP S PA+P + S V L
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 15/120 (12%)
Query: 59 PAAG-LSAAPVPTAPAAGAPLMDFGNDFVPPAPRG--PLPAAPPVAPERQPSWDPSPVSS 115
PA G LS++P+ T +G VPP PLPA P +P P P P++
Sbjct: 294 PALGPLSSSPLATPSPSGTKARP-----VPPPDNAATPLPATLPPSP---PLATPLPLAP 345
Query: 116 TVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPP----APAPAAPPS 171
P+ P SP P PP+ PP A S Q P P +P+ APPS
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/149 (27%), Positives = 57/149 (38%), Gaps = 37/149 (24%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPV-APERQPSWDPSPVSST- 116
P+A L +P+ T P P++ VPP+P PA+P + AP R P+ P P +S
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPT--PGPDTSVS 868
Query: 117 --------VPAPSP------------------LSAAAVSPSKLPEDDEPP---ARPPPPP 147
P P P S+A +P +L D P A PPP
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
A ++ W+ P A P AP
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAP 957
Score = 35.0 bits (79), Expect = 0.11
Identities = 43/160 (26%), Positives = 54/160 (33%), Gaps = 33/160 (20%)
Query: 57 RKP----AAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
RKP A G+ A +P + P G PA R P AP + + P P
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT-SPGP 113
Query: 113 VSSTVPA-----PSPLSA----------------------AAVSPSKLPEDDEPPARPPP 145
VSS A P PL +A+S + P P
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173
Query: 146 PPPASVSPQAEPVWTPPAPAPAAPPSTPA-APKRRGSSGS 184
P A S A P PAP+A P P P++ SS S
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS 213
Score = 34.3 bits (77), Expect = 0.19
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 101 APERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP---PPASVSPQAEP 157
A R+ + P+P + + PA + S AA + LP P ARP PP P SVS +E
Sbjct: 158 AGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRP-APSARPRPPTEGPRKSVSSASEH 215
Query: 158 VWTPPAPAPAAPPSTPAAPKRRGS 181
T P+PA PS +R S
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPAS 239
Score = 31.2 bits (69), Expect = 1.6
Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 9/83 (10%)
Query: 50 EELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPP-----APRGPLPAAPPVAPER 104
EEL + P G +A+P P A A + PP AP PLP P P
Sbjct: 909 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968
Query: 105 QPS----WDPSPVSSTVPAPSPL 123
++ S PAP L
Sbjct: 969 ADGLCTIYETEGPESATPAPGAL 991
Score = 29.6 bits (65), Expect = 4.6
Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 24/130 (18%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSW-DPSPVSSTV 117
P + L+ + + + G+P + + F+ +PR + Q S PS +ST
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPR-----------QTQASLTSPSRPASTP 451
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P PL A P LP PP S+SP P+ +P P S+ A+
Sbjct: 452 PDSPPLQA----PLSLPAS--------PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 178 RRGSSGSVVV 187
+ S+++
Sbjct: 500 PQAPLSSLIM 509
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,753,461
Number of Sequences: 37866
Number of extensions: 1390713
Number of successful extensions: 62021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1558
Number of HSP's successfully gapped in prelim test: 1787
Number of HSP's that attempted gapping in prelim test: 17309
Number of HSP's gapped (non-prelim): 21995
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.