Guide to the Human Genome
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Search of human proteins with 24308215

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24308215 retrotransposon gag domain containing 1 [Homo
sapiens]
         (1388 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]   2681   0.0  
gi|91982772 mucin 17 [Homo sapiens]                                   159   2e-38
gi|167736355 mucin 4 isoform a [Homo sapiens]                         142   2e-33
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       110   7e-24
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...   110   1e-23
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      105   2e-22
gi|83367077 mucin 16 [Homo sapiens]                                   105   4e-22
gi|98986457 host cell factor 1 [Homo sapiens]                         102   3e-21
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    99   3e-20
gi|163965366 nascent polypeptide-associated complex alpha subuni...    97   8e-20
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        97   1e-19
gi|161019170 mucin 5AC [Homo sapiens]                                  96   2e-19
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    91   1e-17
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            91   1e-17
gi|151301154 mucin 6, gastric [Homo sapiens]                           89   3e-17
gi|116284392 mucin 2 precursor [Homo sapiens]                          87   1e-16
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            85   4e-16
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            85   4e-16
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            85   4e-16
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         85   6e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    84   7e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    82   3e-15
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            81   6e-15
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            81   6e-15
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            80   1e-14
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            80   1e-14
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    80   1e-14
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            80   1e-14
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            80   1e-14
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    79   2e-14

>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 2681 bits (6949), Expect = 0.0
 Identities = 1388/1388 (100%), Positives = 1388/1388 (100%)

Query: 1    MSIPLHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGG 60
            MSIPLHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGG
Sbjct: 1    MSIPLHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGG 60

Query: 61   TSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPA 120
            TSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPA
Sbjct: 61   TSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPA 120

Query: 121  LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTP 180
            LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTP
Sbjct: 121  LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTP 180

Query: 181  IMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTE 240
            IMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTE
Sbjct: 181  IMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTE 240

Query: 241  AMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMS 300
            AMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMS
Sbjct: 241  AMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMS 300

Query: 301  DLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMP 360
            DLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMP
Sbjct: 301  DLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMP 360

Query: 361  TQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPA 420
            TQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPA
Sbjct: 361  TQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPA 420

Query: 421  SGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGS 480
            SGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGS
Sbjct: 421  SGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGS 480

Query: 481  MKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQ 540
            MKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQ
Sbjct: 481  MKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQ 540

Query: 541  MRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGV 600
            MRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGV
Sbjct: 541  MRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGV 600

Query: 601  MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTD 660
            MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTD
Sbjct: 601  MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTD 660

Query: 661  TASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLS 720
            TASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLS
Sbjct: 661  TASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLS 720

Query: 721  QPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGER 780
            QPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGER
Sbjct: 721  QPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGER 780

Query: 781  PSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAP 840
            PSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAP
Sbjct: 781  PSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAP 840

Query: 841  ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSP 900
            ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSP
Sbjct: 841  ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSP 900

Query: 901  LVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASG 960
            LVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASG
Sbjct: 901  LVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASG 960

Query: 961  TMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIR 1020
            TMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIR
Sbjct: 961  TMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIR 1020

Query: 1021 ASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPG 1080
            ASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPG
Sbjct: 1021 ASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPG 1080

Query: 1081 TMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS 1140
            TMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS
Sbjct: 1081 TMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS 1140

Query: 1141 FGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSERMAFLVSLHLGAAERW 1200
            FGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSERMAFLVSLHLGAAERW
Sbjct: 1141 FGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSERMAFLVSLHLGAAERW 1200

Query: 1201 FILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQGQKSVRQYATDFLLLA 1260
            FILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQGQKSVRQYATDFLLLA
Sbjct: 1201 FILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQGQKSVRQYATDFLLLA 1260

Query: 1261 RHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRSLYTECQLAEEKDSPGN 1320
            RHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRSLYTECQLAEEKDSPGN
Sbjct: 1261 RHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRSLYTECQLAEEKDSPGN 1320

Query: 1321 SSQVLPTACKRNNEEAMGNELSSQQQTEEHQHVSKRCYYLKEHGDPQEGLHDHLGQSTGH 1380
            SSQVLPTACKRNNEEAMGNELSSQQQTEEHQHVSKRCYYLKEHGDPQEGLHDHLGQSTGH
Sbjct: 1321 SSQVLPTACKRNNEEAMGNELSSQQQTEEHQHVSKRCYYLKEHGDPQEGLHDHLGQSTGH 1380

Query: 1381 HQKAHTNK 1388
            HQKAHTNK
Sbjct: 1381 HQKAHTNK 1388


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  159 bits (402), Expect = 2e-38
 Identities = 299/1197 (24%), Positives = 458/1197 (38%), Gaps = 157/1197 (13%)

Query: 49   PIVSTSASDPGGTSTQLMTSPVFDTMSAPL-------MGVPNSGALSPPLM-----PASD 96
            P  S + S+    ST L  S   DT S          M  P+  ++S  +      P   
Sbjct: 112  PTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPS 171

Query: 97   SGALSPLLMPASDSGALSPLLM----PALDSGTLSPLLSTSEYGVMSPGM--MTIPDFGT 150
              A + L      S  L+        P     T  P  + SE       M   T+    +
Sbjct: 172  FEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASS 231

Query: 151  MSATLMVAPDSAEIS-PLAMPAPSSGVVCT---PIMSTSSSEAMSTPLMLAPDSGELSPI 206
             + TL+  P   EIS P+ + A +S    T   P +S S+    STPL   P    LS +
Sbjct: 232  EAITLLTTP--VEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMP----LSVM 285

Query: 207  LMQDMNPGVMSTQP----VPAPSSEAMSPLQITDEDTEAMSKVLM---TALASGEISSLL 259
            L+       +ST P    +P  +S   S    T E T   +       T L S   S++ 
Sbjct: 286  LVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMP 345

Query: 260  MSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSG--------IMSSLL 311
            ++ ++   +S   +       TS +P+S   +    + L S L  G        + + L+
Sbjct: 346  VATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILV 405

Query: 312  MSSPGSEVMSTPLLS---VPDAGEMSTLPKPAPDAE-AMSPALMTALPSGVMPTQTMPAP 367
             SS  S   + P+ S   V  A E S+ P  A D   A S     + P   MP  T P  
Sbjct: 406  ASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVA 465

Query: 368  GSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTL 427
             S A S  ST  VDS+         T++   S+PP   ++S   STP  G+    +MS  
Sbjct: 466  SSEA-SNLSTTPVDSKTQVT-----TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519

Query: 428  QKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL--TMAKTSGAMPTGSMKAVA 485
               V +S A T S   V +S  ++T   ++++S         T   + G+ P  +M    
Sbjct: 520  TMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST 579

Query: 486  KQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASG----SMSMLQM 541
            +    + AS   +TP          S    ++T +E  SMP  T    G    SMS+   
Sbjct: 580  RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639

Query: 542  RAPVSEAMSMPQM-------------RTMASGLTSAAQMKAMTSGAMSTPL--------M 580
                SEA ++                 T +S       M   T    STPL        +
Sbjct: 640  LVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTL 699

Query: 581  TAQTSGSTSTLLMRDTASGVMSCPQMRS---LASGALSKPLMTPKASGTMFT----EKMT 633
             A +  ST +    DT++ V +  +  S    A GA S P  TP    T  T     K  
Sbjct: 700  VASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA-SMPTSTPSEGSTPLTSMPVSKTL 758

Query: 634  TTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTS------QM 684
             T+SEA     T L   T     +    + T + G S  +   +    + TS       +
Sbjct: 759  LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV 818

Query: 685  TATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGM 744
            T+  +  +S   + +  P      +  +    +  S P ST   G    +P+ SM     
Sbjct: 819  TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEG---RTPLTSMPVSTT 875

Query: 745  QMNSPTSDVMSTPTVRAWTSETMSTPL-----------MRTSDPGERPSLLTRASSSGEM 793
             + +     +ST  V   T  T ST             M TS PGE  + LT   S  + 
Sbjct: 876  LVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLT---SMPDS 932

Query: 794  SLPLMRAPASGEIATPL--RSPAYGAMSAPQMTATASGMMSSMPQVKAPISGA---MSMP 848
            + P++ + A    ATP+   +P   +  A     TA G  +S+P    P  G     S P
Sbjct: 933  TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEG--TSIP-TSTPSEGTTPLTSTP 989

Query: 849  LTRSTASGGMSMPLMRAP-DSR---VTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRA 904
            ++ +  +   +  L   P DS     TST    P  + +  ++P   P+ G  S+PL R 
Sbjct: 990  VSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEG--STPLTRM 1047

Query: 905  PASGTM------STPLRRPSACETVSTELMRASASGHMS--TAQTTAMVSGGMSKPLMRA 956
            P S TM      ST    P+   T  T   +AS+S   +  T+  T+  S G S PL   
Sbjct: 1048 PVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEG-STPLTSV 1106

Query: 957  PASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMAT 1016
            P S  +   ++S+ AS   + P ++T     TST  +S   +   +   T+    G   T
Sbjct: 1107 PVSTRL---VVSSEASTLSTTP-VDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEG---T 1159

Query: 1017 APIRASASGARSTSFMRASVSGSM-PMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMR 1075
             P+   AS   ST+ + +S + ++   P+   T        S P  TA          M 
Sbjct: 1160 TPL---ASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTA------EVTSMP 1210

Query: 1076 ASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAK 1132
             S PG  STP T+  V  TP + ++++   STS ++   S    TS  T+++P TA+
Sbjct: 1211 TSTPGERSTPLTSMPVRHTP-VASSEASTLSTSPVD--TSTPVTTSAETSSSPTTAE 1264



 Score =  150 bits (380), Expect = 6e-36
 Identities = 282/1183 (23%), Positives = 480/1183 (40%), Gaps = 156/1183 (13%)

Query: 11   NNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVST--SASDPGGTSTQLMTS 68
            ++T  E    P +       P+T    +  ++ S     + +T    S P  TST+  +S
Sbjct: 669  SSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSS 728

Query: 69   PVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSP 128
            P     ++     P+ G+     MP S +      L+ +S++  LS      LD+ T   
Sbjct: 729  PTTADGASMPTSTPSEGSTPLTSMPVSKT------LLTSSEASTLS---TTPLDTST--- 776

Query: 129  LLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSE 188
             ++TS     SP         T   T M     +E SPL    P   V  TP+ S  +S 
Sbjct: 777  HITTSTEASCSP--------TTTEGTSMPISTPSEGSPLLTSIP---VSITPVTSPEAST 825

Query: 189  AMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPS--------SEAMSPLQITDEDTE 240
              +TP+    DS   SP+         +S+ P PA          SE  +PL      T 
Sbjct: 826  LSTTPV----DSN--SPVTTST----EVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTT 875

Query: 241  AMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMS 300
             ++   ++ L++  + +       +EA S    S   S GTS  PTST   G  P   M 
Sbjct: 876  LVATSAISTLSTTPVDTSTPVTNSTEARS----SPTTSEGTS-MPTSTPGEGSTPLTSMP 930

Query: 301  DLDSGIMSSLLMSSPGSEV-------MSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA 353
            D  + ++SS   +   + V        ST   S P   E +++P   P +E  +P   T 
Sbjct: 931  DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP-SEGTTPLTSTP 989

Query: 354  LPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMST 413
            +      + T+ A  +   S  ST  VD    SN P+  T++   S PP     S   ST
Sbjct: 990  V------SHTLVA--NSEASTLSTTPVD----SNTPL-TTSTEASSPPPTAEGTSMPTST 1036

Query: 414  PLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVM--SAQLTMAK 471
            P  G+     M      V +S   T S     +S  ++T   ++++S     ++  T   
Sbjct: 1037 PSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTY 1096

Query: 472  TSGAMPTGSMKAVAKQYKRATASGKMSTPLRRA---PTSGAMSTQPVTATASETMSMPQL 528
            + G+ P  S+    +    + AS   +TP+  +    TS   S+ P TA  +   + P  
Sbjct: 1097 SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP-- 1154

Query: 529  TVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQ-TSGS 587
              P+ G+  +  M  PVS  + +       S     ++ +  TS   S+P  TA+ TS  
Sbjct: 1155 --PSEGTTPLASM--PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP 1210

Query: 588  TSTLLMRD---TASGVMSCPQMRSLASGALSKPL--MTPKASGTMFTEKMTTTASEAMPT 642
            TST   R    T+  V   P   S AS   + P+   TP  +    +   TT    ++PT
Sbjct: 1211 TSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPT 1270

Query: 643  LLMRDTVSGALSMPQMTDTASGGLSASLMR---DTASGAMSTSQMTA--TVSGGMSMPLM 697
                +  +   S+P  T   +   +++L+    DT    ++++++++  T + G SMP  
Sbjct: 1271 STTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS 1330

Query: 698  RAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTP 757
               + G  P           + S P++T      ++S + +         + +++  S+P
Sbjct: 1331 TYSE-GRTP-----------LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSP 1378

Query: 758  TVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
            T    TSE  S P    S+P E  + LT    S   + P++ + AS   ATP+ +   G 
Sbjct: 1379 T----TSEGTSMP---NSNPSEGTTPLTSIPVS---TTPVVSSEASTLSATPVDTSTPGT 1428

Query: 818  MSAPQMTA--TASGM---MSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAP-DSR-- 869
             SA   ++  TA G+    S+  + K P+    S+P++ +  +   +  L   P DS   
Sbjct: 1429 TSAEATSSPTTAEGISIPTSTPSEGKTPLK---SIPVSNTPVANSEASTLSTTPVDSNSP 1485

Query: 870  -VTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAP------ASGTMSTPLRRPSACET 922
             VTST+        +  ++ +  P+ G  S+ L   P      AS  +++    P+   T
Sbjct: 1486 VVTSTAVSSSPTPAEGTSIAISTPSEG--STALTSIPVSTTTVASSEINSLSTTPAVTST 1543

Query: 923  VSTELMRASASGHMS--TAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL- 979
              T   +AS+S   +  T+  T+  S G S PL   P S    M ++S+ A+   + P+ 
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQTSTYSEG-STPLTSLPVS---TMLVVSSEANTLSTTPID 1599

Query: 980  METMASGATSTLQTSVANSRSMSLSQ----TTYTVSGRMATAPIRASASGARSTSFMRAS 1035
             +T  + +T    ++ A   SM++S     +    S  ++T P+ +  +   ST+     
Sbjct: 1600 SKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTT----P 1655

Query: 1036 VSGSMPMPLPRATASG--CGMGMSMPQMTATDSRGMSTPLMRASGP---GTMSTPQTAFG 1090
            V  + P+      +S      G SMP  T T+ R   T +   + P     +ST  T   
Sbjct: 1656 VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPV 1715

Query: 1091 VMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
              STP   +T++  + T+    +   S P+     TTP T+ P
Sbjct: 1716 DNSTPVTTSTEARSSPTTSEGTSMPNSTPSE---GTTPLTSIP 1755



 Score =  149 bits (377), Expect = 1e-35
 Identities = 287/1196 (23%), Positives = 479/1196 (40%), Gaps = 156/1196 (13%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASD- 109
            VS+S     GTS Q  T   +     PL  +P    +S  ++ +S    LS   +  S  
Sbjct: 2139 VSSSPIPTEGTSMQTST---YSDRRTPLTSMP----VSTTVVASSAISTLSTTPVDTSTP 2191

Query: 110  -SGALSPLLMPALDSGTLSPLLSTSEYGVMSPGM--MTIPDFGTMSATLMVAP-DSAEIS 165
             + +      P    GT  P  + SE       M   T+P   + ++TL   P D++   
Sbjct: 2192 VTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPV 2251

Query: 166  PLAMPAPSSGVVC--TPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPV-- 221
              +  A SS      T I +++ SE  +TPL   P    +S  L+ +     +ST PV  
Sbjct: 2252 TTSTEATSSPTTAEGTSIPTSTLSEG-TTPLTSIP----VSHTLVANSEVSTLSTTPVDS 2306

Query: 222  ------------PAPSSEAMS-PLQITDEDTEAMSK--VLMTALASGEISSLLMSGTDSE 266
                        P P++E  S P   + E    +++  V  T +AS E S+L  +  D+ 
Sbjct: 2307 NTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADT- 2365

Query: 267  AISSLIMSAVASGGTSP-------QPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEV 319
               S  ++  +  G+SP        PTST + G   TPL S     + +  ++SS  S  
Sbjct: 2366 ---STPVTTYSQAGSSPTTADDTSMPTSTYSEGS--TPLTS---VPVSTMPVVSSEASTH 2417

Query: 320  MSTPL---LSVPDAGEMSTLPKPAPDAEA-MSPALMTALPSGVMPTQTMPAPGSGAMSPW 375
             +TP+     V  + E S+ P  A       SP      P   MP  T P   S A    
Sbjct: 2418 STTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEA-GTL 2476

Query: 376  STQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASG 435
            ST  VD+         A++S   +   V  + + +  + L+    S  +ST     P + 
Sbjct: 2477 STTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLL---TSIPVSTTPVASPEAS 2533

Query: 436  AMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASG 495
             ++T+ +   S  V STE  S+  S   ++  T   + G+ P  SM    K    + AS 
Sbjct: 2534 TLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST 2593

Query: 496  KMSTPLRRA---PTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQ-----MRAPVSE 547
              +TP+  +    TS   S+ P TA   +  SMP ++ P+  S S+       M    SE
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTA---KDTSMP-ISTPSEVSTSLTSILVSTMPVASSE 2649

Query: 548  AMSMP-------QMRTMASGLTSA------AQMKAMTSGAMSTPL--------MTAQTSG 586
            A ++         + T ++G +S+      + M   T G  STPL        + A +  
Sbjct: 2650 ASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEA 2709

Query: 587  STSTLLMRDTASGVMSCPQMRSLASGA--LSKPLMTPKASGTMFTEKMTTTASEAMPTLL 644
            ST +    DT++ V +  +  S  + A   S  + TP    T  T  + +T   A     
Sbjct: 2710 STLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAS 2769

Query: 645  MRDTVSGALSMPQMTDTASGGLSASLMRDTAS-GAMSTSQMTATVSGGMSMPLMRAQDPG 703
               T +   S+P  T T      AS    TA   +M TS  + T +   SMP+       
Sbjct: 2770 TVSTTAVDTSIPVTTST-----EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVAS 2824

Query: 704  VMPASLMRAKVSGKMLSQPMSTQDPGGMS-------MSPMKSMTAGGMQMNSPTSDVMST 756
                +L    V     S P++T      S       + P+ + + G   +   TS  +ST
Sbjct: 2825 SEAGTLSTTPVD---TSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLL---TSIPVST 2878

Query: 757  PTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGE-MSLPLMRAPASGEIATPLRSPAY 815
              V +  + T+ST  + TS P    +  + + ++ E  S+P+       E++TPL S   
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPI---STPSEVSTPLTSIL- 2934

Query: 816  GAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS- 874
               + P   + AS + ++    + P++ +     + +TA  G SMP+    + R   TS 
Sbjct: 2935 -VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE-GTSMPISTPGERRTPLTSM 2992

Query: 875  --QMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMST-------PLRRPSACETVST 925
                MP AS +  TL  R PA    S+P+  +  + +  T       P+  PS   T  T
Sbjct: 2993 SVSTMPVASSEASTLS-RTPAD--TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLT 3049

Query: 926  ELMRASASGHMSTAQTTAMVSGGMSKPLMRA--------PASGT-MPMPLMSAMASGEMS 976
             +  ++    +  A T +      + P++ +        PA GT MP+   S  ++    
Sbjct: 3050 SIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTG 3109

Query: 977  MPLMET-MASGATSTLQTS-VANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRA 1034
            +P+  T + S A STL T+ V  S  ++ S   ++         +  S     ST     
Sbjct: 3110 VPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM 3169

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST---PLMRASGPGTMSTPQTAFGV 1091
             VS  + +    +T S   +  S P  T+T++   +T     +  S P    TP T+  V
Sbjct: 3170 PVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV 3229

Query: 1092 MSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPA 1147
             +TP + ++++   ST+ ++         + +T +T  ++ PP  E  S    TP+
Sbjct: 3230 SNTP-VASSEASILSTTPVD-------SNTPLTTSTEASSSPPTAEGTSMPTSTPS 3277



 Score =  148 bits (373), Expect = 4e-35
 Identities = 246/1161 (21%), Positives = 452/1161 (38%), Gaps = 114/1161 (9%)

Query: 56   SDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSP 115
            S P  TST+  +SP     +   +  P+ G+     +P S +    P+ +P + + + +P
Sbjct: 3015 STPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT----PVAIPEASTLSTTP 3070

Query: 116  L-------------LMPALDSGTLSPLLSTSEYGVMSPGM--MTIPDFGTMSATLMVAP- 159
            +               P    GT  P+ + SE      G+   T P   +  +TL   P 
Sbjct: 3071 VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPV 3130

Query: 160  DSAEISPLAMPAPSSGVVCTPI-MSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMST 218
            D++     +  A SS        M TS+    STPL   P    +S +L+       +S 
Sbjct: 3131 DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP----VSTMLVVSSEDSTLSA 3186

Query: 219  QPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASG--EISSLLMSGTDSEAISSLIMSAV 276
             PV   S+   +  + T   T   + +  +  + G   ++S+ +S T   +  + I+S  
Sbjct: 3187 TPVDT-STPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245

Query: 277  ASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTL 336
                 +P  TST+ S   PT        G  +S+  S+P     STPL S+P +   +T+
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTA------EG--TSMPTSTPSEG--STPLTSMPVS--TTTV 3293

Query: 337  PKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSN-----PPVR 391
                    + +PA  +   +      + P    G   P ST +  S  ++N      PV 
Sbjct: 3294 ASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVV 3353

Query: 392  ATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMS 451
            ++ +  +S  PV        ST    +P +   +++  + P+ G    + M V ++ V+S
Sbjct: 3354 SSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVS 3413

Query: 452  TEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATAS-GKMSTPLRRAPTSGAM 510
            +E  + + + V S  L    T  +    S   +A+     T++  + STPL   P    +
Sbjct: 3414 SEVNTLSTTPVDSNTLVTTSTEAS----SSPTIAEGTSLPTSTTSEGSTPLSIMP----L 3465

Query: 511  STQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAM 570
            ST PV ++ + T+S   +      + S     +P +  ++     T   G T    M   
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS 3525

Query: 571  TSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTE 630
            T+   S+   T  T+   S   +  ++S   S P    + +  +S P     +  TM   
Sbjct: 3526 TTPVASSEASTLSTTPVDSNTFVT-SSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584

Query: 631  KMTTTASEAMP---------TLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMST 681
                T+SEA           T +   T S +   P    T      + +        +ST
Sbjct: 3585 STYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVST 3644

Query: 682  SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG-----MSMSPM 736
            + +T + +G  S   +    P +    +  + V+ +  + P+ T   G      M +S  
Sbjct: 3645 TSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTT 3704

Query: 737  KSMTAGGMQMNSP---TSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEM 793
            +  ++ G  +++P   TS  ++T T    +S T+ +  M  S P E  +L T    S   
Sbjct: 3705 RVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS--- 3761

Query: 794  SLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRST 853
            + P+ R P S   +TP     Y +MS   MT  + G  SS P     + G  +MP++ ++
Sbjct: 3762 TTPVTRFPES---STPSIPSVYTSMS---MTTASEG--SSSPTT---LEGTTTMPMSTTS 3810

Query: 854  ASGGMSMPLMRAPDSRVT-STSQMMPTASGDMCTLPVRAPASGGVSSPL----VRAPASG 908
                +   ++ +P S ++ S +  + T  GD  T  + +  +G  S P     +R   + 
Sbjct: 3811 ERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITS 3870

Query: 909  TMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMS 968
              STPL       T+ T    AS +       +T       +      P + T+ + +++
Sbjct: 3871 ERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVIT 3930

Query: 969  AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARS 1028
              ++   ++ +  T  +  +ST     A + ++S    T T     +T+    + S + +
Sbjct: 3931 EGSTPGTTIFIPSTPVT--SSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988

Query: 1029 TSFMRASVSGSMPMPL---------PRATASGCGMGMSMPQMTATDSRGMS------TPL 1073
              F   +++ + P+           PR T+ GC    S    T+T     S      TP 
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPS 4048

Query: 1074 MRASGPGTMST----PQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTA--TT 1127
              +S P T+++    P       STP   +  S   +   +    + +KP++  T+  T 
Sbjct: 4049 SESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTV 4108

Query: 1128 PETAKPPPKEVPSFGMLTPAL 1148
              TA P    + S    TP +
Sbjct: 4109 TTTAVPTNTTIKSNPTSTPTV 4129



 Score =  143 bits (361), Expect = 1e-33
 Identities = 282/1138 (24%), Positives = 451/1138 (39%), Gaps = 138/1138 (12%)

Query: 62   STQLMTSPVFDTMSAPLM--GVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMP 119
            ST L+ +    T+S   +    P + +      P +  G   P   P   S  L+   MP
Sbjct: 873  STTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTS--MP 930

Query: 120  ALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCT 179
              DS T  P++S SE   +S   +      T S     +P +AE + +    PS G   T
Sbjct: 931  --DSTT--PVVS-SEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT--T 983

Query: 180  PIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPV-PAPSSEAMS-PLQITDE 237
            P+ ST  S      L+   ++  LS   +    P   ST+   P P++E  S P     E
Sbjct: 984  PLTSTPVSHT----LVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSE 1039

Query: 238  DTEAMSK--VLMTALASGEISSLLMSGTDSEA----ISSLIMSAVASGGTSPQPTSTQNS 291
             +  +++  V  T +AS E S+L  +  D+       S    S+  + GTS  PTST + 
Sbjct: 1040 GSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTS-MPTSTYSE 1098

Query: 292  GGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL---LSVPDAGEMSTLPKPAPDAEA-MS 347
            G   TPL S     + + L++SS  S + +TP+   + V  + E S+ P  A       S
Sbjct: 1099 GS--TPLTS---VPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS 1153

Query: 348  PALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALD 407
            P      P   MP  T     S A +  ST  VDS+        AT++   S PP   + 
Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEA-NTLSTTPVDSKTQV-----ATSTEASSPPPTAEVT 1207

Query: 408  SGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL 467
            S   STP   +    +M      V +S A T S   V +S  ++T   + T+S   +A+ 
Sbjct: 1208 SMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTS--AETSSSPTTAEG 1265

Query: 468  TMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPV-----TATASET 522
            T   TS             +      S  +ST L  +P +  + T PV       T++E 
Sbjct: 1266 TSLPTS----------TTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEV 1315

Query: 523  MSMPQLTVPASG-SMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMT 581
             S P    PA G SM         +   S+P   T+ +  +SA  + + T    STP+ T
Sbjct: 1316 SSSP---TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA--SSAISILSTTPVDNSTPVTT 1370

Query: 582  AQTSGSTSTLLMRDTASGVMSCPQMRSLASGALS-KPLMTPKASGTMFTEKMTTTASEAM 640
            +  + S+ T     +            L S  +S  P+++ +AS    T   T+T     
Sbjct: 1371 STEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTS 1430

Query: 641  PTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQ 700
                   T +  +S+P  T T S G +        S  +S + +  + +  +S   + + 
Sbjct: 1431 AEATSSPTTAEGISIP--TSTPSEGKT-----PLKSIPVSNTPVANSEASTLSTTPVDSN 1483

Query: 701  DPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMS--PMKSMTAGGMQMNSPTSDVMSTPT 758
             P V   ++  +    +  S  +ST   G  +++  P+ + T    ++NS    + +TP 
Sbjct: 1484 SPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINS----LSTTPA 1539

Query: 759  VRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEI----------AT 808
            V   TS  ++T    +S P        + S+  E S PL   P S  +           T
Sbjct: 1540 V---TSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTT 1596

Query: 809  PLRSPAYGAMS---APQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
            P+ S      S   +   TA  S M  S P   +P+    S+P++ +  +   +  L   
Sbjct: 1597 PIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL--LTSIPVSTTPVASPEASTLSTT 1654

Query: 866  P-DSR---VTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE 921
            P DS    +TST         +  ++P      G   +PL     S T+ T     SA  
Sbjct: 1655 PVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG--RTPL----TSITVRTTPVASSAIS 1708

Query: 922  TVSTELMRASASGHMST-AQTTAMVSGGMSKPLMRAPASGTMPM--------PLMSAMAS 972
            T+ST  +  S     ST A+++   S G S P    P+ GT P+        P++S+ AS
Sbjct: 1709 TLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP-NSTPSEGTTPLTSIPVSTTPVLSSEAS 1767

Query: 973  GEMSMPLMETMASGATSTLQTS---VANSRSMSLSQTTYTVSGRMATAPIRASASGARST 1029
               + P+ +T     TST  TS    A   S+  S  +  ++   +T       + + ++
Sbjct: 1768 TLSATPI-DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAS 1826

Query: 1030 SFMRASVSGSMPMPLPRATAS------GCGMGMSMPQ--MTATDSRGMSTPLMRASGPGT 1081
            +     V  + P+    A +S      G  +  S P    TA  S  +ST  + +S   T
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886

Query: 1082 MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVP 1139
            +ST      V STP    T   + S+S    TA GS     M  +TP   +PP   +P
Sbjct: 1887 LSTTP---AVTSTP---VTTYAQVSSS--PTTADGSS----MPTSTPREGRPPLTSIP 1932



 Score =  140 bits (354), Expect = 6e-33
 Identities = 256/1128 (22%), Positives = 444/1128 (39%), Gaps = 214/1128 (18%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPA 107
            L       S P  TST+  +SP     ++     P+ G+     MP      +S +L+ +
Sbjct: 3125 LSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP------VSTMLVVS 3178

Query: 108  SDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPL 167
            S+   LS     A    T +P+ +++E               T S T       AE + +
Sbjct: 3179 SEDSTLS-----ATPVDTSTPVTTSTE--------------ATSSTT-------AEGTSI 3212

Query: 168  AMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPA-PSS 226
                PS G+  TP+ S   S   +TP + + ++  LS   +    P   ST+   + P++
Sbjct: 3213 PTSTPSEGM--TPLTSVPVS---NTP-VASSEASILSTTPVDSNTPLTTSTEASSSPPTA 3266

Query: 227  EAMS-PLQITDEDTEAMSK--VLMTALASGEISSLLMSGTDSE----AISSLIMSAVASG 279
            E  S P     E +  ++   V  T +AS E S+L  +  D+       S    S   + 
Sbjct: 3267 EGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIAD 3326

Query: 280  GTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL---LSVPDAGEMSTL 336
            GTS  PTST + G  P   MS       ++ ++SS  S + +TP+     V  + E S  
Sbjct: 3327 GTS-MPTSTYSEGSTPLTNMS-----FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 337  PKPAPDAEAMSPALMTALPS-GVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATAS 395
            P       A   ++ T+ PS G  P  +MP                   +S  PV ++  
Sbjct: 3381 P-----TTAEGTSIPTSSPSEGTTPLASMP-------------------VSTTPVVSSEV 3416

Query: 396  GVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQM 455
              +S  PV +      ST    +P     ++L  +  + G+   S+M + ++ V S+E  
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAS 3476

Query: 456  SATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATA-SGKMSTPLRRAPTS------- 507
            + + + V     T    + + PT S    A+     T+ +G+ STPL   P S       
Sbjct: 3477 TLSTTPVD----TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532

Query: 508  --GAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSA- 564
                +ST PV +    T S    + PA+  ++ ++M  P   + S+  M   ++ +TS+ 
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 565  AQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKAS 624
            A   +  S   STP+ T+  S ST T             P++ +L       P+ TP   
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPT------------PPEVITL-------PMSTPSEV 3633

Query: 625  GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM 684
             T  T          MP      T+S A            G +++L  DT++  ++++Q+
Sbjct: 3634 STPLT---------IMPVSTTSVTISEA------------GTASTLPVDTSTPVITSTQV 3672

Query: 685  TAT--VSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAG 742
            +++     G +MP+    +                  S P++T     M +S  +  ++ 
Sbjct: 3673 SSSPVTPEGTTMPIWTPSEG-----------------STPLTT-----MPVSTTRVTSSE 3710

Query: 743  GMQMNSP---TSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMR 799
            G  +++P   TS  ++T T    +S T+ +  M  S P E  +L T    S   + P+ R
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS---TTPVTR 3767

Query: 800  APASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMS 859
             P   E +TP     Y +MS   MT  + G  SS P     + G  +MP++ ++    + 
Sbjct: 3768 FP---ESSTPSIPSVYTSMS---MTTASEG--SSSP---TTLEGTTTMPMSTTSERSTLL 3816

Query: 860  MPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
              ++ +P       S M P+ +  + T P      G  S+PL+ +  +G+ S P      
Sbjct: 3817 TTVLISP------ISVMSPSEASTLSTPP------GDTSTPLLTSTKAGSFSIP------ 3858

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAM--ASGEMSM 977
                    +R S +   ST  TT +VS  +      A  + T P+   +    ++   S 
Sbjct: 3859 ---AEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAST 3915

Query: 978  PLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVS 1037
            P +    + + S +        ++ +  T  T S    TA +  + +GA ST      V 
Sbjct: 3916 PTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS----TADVFPATTGAVST-----PVI 3966

Query: 1038 GSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFG--VMSTP 1095
             S  +  P  ++S      S  +   T +   + PL   +     STP+T       S  
Sbjct: 3967 TSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAS 4026

Query: 1096 EIKATDSGEASTS----HINITASGSKPTSHMTATTPETAKPPPKEVP 1139
             + AT +   STS     +  ++  S+P++  + T P T  P     P
Sbjct: 4027 TLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTP 4074



 Score =  140 bits (353), Expect = 8e-33
 Identities = 246/1049 (23%), Positives = 412/1049 (39%), Gaps = 137/1049 (13%)

Query: 150  TMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQ 209
            T S     +P +AE + +    PS G   TP+    +S  +ST  +++ ++G LS   + 
Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGT--TPL----ASMPVSTTPVVSSEAGTLSTTPVD 2482

Query: 210  DMNPGVMSTQPVPAPSS--EAMSPLQITDEDTEAMSKVLM--TALASGEISSLLMSGTDS 265
               P   ST+   +P++  + + P+    E +  ++ + +  T +AS E S+L  +  DS
Sbjct: 2483 TSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDS 2542

Query: 266  EA---ISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMST 322
             +    S+ I S+  S   +  PTST + G  P   M      + +  L SS  S + +T
Sbjct: 2543 NSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMP-----VSTKPLASSEASTLSTT 2597

Query: 323  PL---LSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQN 379
            P+   + V  + E S+ P  A D                MP  T P+  S +++      
Sbjct: 2598 PVDTSIPVTTSTETSSSPTTAKDTS--------------MPIST-PSEVSTSLT------ 2636

Query: 380  VDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTT 439
              S ++S  PV ++ +  +S  PV        ST    +P +   S++  + P  G  +T
Sbjct: 2637 --SILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTP--GERST 2692

Query: 440  SLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMST 499
             L  +  S  +     ++T S       T   TS    +    A     + +T S   ST
Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG-ST 2751

Query: 500  PLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVS-EAMSMPQ----- 553
            PL    TS  +ST PV ++ + T+S   +      + S     +P + E  SMP      
Sbjct: 2752 PL----TSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSE 2807

Query: 554  ----MRTMASGLTSAAQMKAMTSGAM----STPLMTAQTSGSTSTLLMRDTASGVMSCPQ 605
                + +M    T  A  +A T        STP+ T+  + S+ T     TA G++    
Sbjct: 2808 TSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPT-----TAEGIVVPIS 2862

Query: 606  MRSLASGALSK-PLMTPKASGTMFTEKMTTTASEAMPTLLMRD-----TVSGALSMPQMT 659
              S  S  L+  P+ T   + +  +   TT    ++P     +     T +   SMP  T
Sbjct: 2863 TASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIST 2922

Query: 660  DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKML 719
             +       S++  T   A S +   +T       P+  + +    P +        +  
Sbjct: 2923 PSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTT-------AEGT 2975

Query: 720  SQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMS-TPTVRAWTSETMSTPLMRTSDPG 778
            S P+ST    G   +P+ SM+   M + S  +  +S TP   A TS  ++T    +S P 
Sbjct: 2976 SMPISTP---GERRTPLTSMSVSTMPVASSEASTLSRTP---ADTSTPVTTSTEASSSPT 3029

Query: 779  ERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMS-------APQMTAT----- 826
                     S+  E S PL   P S    TP+  P    +S       +P +T+T     
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTSIPVS---TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS 3086

Query: 827  ------ASGMMSSMPQVKAPISGA--MSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMP 878
                   S  +S+  +   P++G    + P+T S  S   + P+  +     ++ +   P
Sbjct: 3087 PTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSP 3146

Query: 879  TASGDMCTLPVRAPASGG-------VSSPLVRAPASGTMSTPLRRPSACETVSTELMRAS 931
            T S +  ++P   P+ G        VS+ LV +    T+S      S   T STE    S
Sbjct: 3147 TTS-EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA--TS 3203

Query: 932  ASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME----TMASGA 987
            ++    T+  T+  S GM+ PL   P S T   P+ S+ AS   + P+      T ++ A
Sbjct: 3204 STTAEGTSIPTSTPSEGMT-PLTSVPVSNT---PVASSEASILSTTPVDSNTPLTTSTEA 3259

Query: 988  TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRA 1047
            +S+  T+   S   S      T    M  +    ++S   + S   A  S  +      +
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS 3319

Query: 1048 TASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP---EIKATDSGE 1104
            ++     G SMP  T ++    STPL   S   T      A  + +TP       T S E
Sbjct: 3320 SSPPIADGTSMPTSTYSEG---STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTE 3376

Query: 1105 ASTSHINITASGSKPTSHMTATTPETAKP 1133
            AS S      +    +S    TTP  + P
Sbjct: 3377 ASLSPTTAEGTSIPTSSPSEGTTPLASMP 3405



 Score =  134 bits (338), Expect = 5e-31
 Identities = 273/1194 (22%), Positives = 462/1194 (38%), Gaps = 186/1194 (15%)

Query: 50   IVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASD 109
            + S   S PG  ST L + PV  T       V +S A +    P   S   +P+   A  
Sbjct: 1206 VTSMPTSTPGERSTPLTSMPVRHTP------VASSEASTLSTSPVDTS---TPVTTSAET 1256

Query: 110  SGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAM 169
            S +      P    GT  P  +TSE   +   + +IP    +S TL+ +P+++ +  L  
Sbjct: 1257 SSS------PTTAEGTSLPTSTTSEGSTL---LTSIP----VSTTLVTSPEASTL--LTT 1301

Query: 170  PAPSSG-VVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNP--------GVMSTQP 220
            P  + G VV +  +S+S + A  T +  +  S   +P+    +N          ++ST P
Sbjct: 1302 PVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP 1361

Query: 221  V---------------PAPSSEAMSPLQITDEDTEAMSKVLM--TALASGEISSLLMSGT 263
            V               P  S     P     E T  ++ + +  T + S E S+L  +  
Sbjct: 1362 VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPV 1421

Query: 264  DSEAISSLIMSAVASGGTSPQ---PTSTQNSGGIP--------TPLMS-----------D 301
            D+    +    A +S  T+     PTST + G  P        TP+ +           D
Sbjct: 1422 DTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVD 1481

Query: 302  LDSGIMSSLLMSSPGSEVMSTPL-LSVPDAGE-------MSTLPKPAPDAEAMS--PALM 351
             +S +++S  +SS  +    T + +S P  G        +ST    + +  ++S  PA+ 
Sbjct: 1482 SNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVT 1541

Query: 352  TALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV--------------------- 390
            +   +      + P    G     ST +  S  +++ PV                     
Sbjct: 1542 STPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSK 1601

Query: 391  -RATASGVMSAPPVRALDSGAMSTPLMGAP--ASGNMSTLQKTVPASGAMTTSLMTVPSS 447
             + TAS   S+       S  +STP  G+P   S  +ST     P +  ++T+ +   S 
Sbjct: 1602 TQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSP 1661

Query: 448  GVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTS 507
             + STE  S+      ++  T   T G  P  S+         +  S   +TP+  +   
Sbjct: 1662 VITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV 1721

Query: 508  GAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQM 567
               +    + T SE  SMP  T P+ G+  +  +    +  +S       A+ + ++  +
Sbjct: 1722 TTSTEARSSPTTSEGTSMPNST-PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPV 1780

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTM 627
               T  A S+P     TS  TSTL   +  + + S P   +L + + +  L T       
Sbjct: 1781 TTSTE-ATSSPTTAEGTSIPTSTL--SEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN- 1836

Query: 628  FTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTAT 687
             +  +T+TA  + PT    +  S A S P    TA   +  S    T + A S +   +T
Sbjct: 1837 -SPVVTSTAVSSSPT--PAEGTSIATSTPSEGSTALTSIPVS----TTTVASSETNTLST 1889

Query: 688  VSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMN 747
                 S P+         P +   A  S    S P   + P  ++  P+ + T    ++N
Sbjct: 1890 TPAVTSTPVTTYAQVSSSPTT---ADGSSMPTSTPREGRPP--LTSIPVSTTTVASSEIN 1944

Query: 748  SPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPL-----MRAPA 802
            + ++ +  T T     S+  S+P   T+D    P+      S+   S+PL     + + A
Sbjct: 1945 TLSTTLADTRTPVTTYSQASSSP--TTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEA 2002

Query: 803  SGEIATPL--RSPAYGAMSAPQMTATASG--MMSSMPQVK-APISGAMSMPLTRSTASGG 857
            S    TP+   +PA  +        TA G  + +S P  +  P++G   MP++ +     
Sbjct: 2003 STLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG---MPVSTTLVVSS 2059

Query: 858  MSMPLMRAP---DSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPL 914
                L   P    ++VT++++   +A+ +  ++ + AP+ G   SPL+ +    T  TP+
Sbjct: 2060 EGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEG---SPLLTSIPLST--TPV 2114

Query: 915  RRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT-MPMPLMSAMASG 973
              P A  T+ST  + +++    ST  +++ +           P  GT M     S   + 
Sbjct: 2115 ASPEA-STLSTTPVDSNSPVITSTEVSSSPI-----------PTEGTSMQTSTYSDRRTP 2162

Query: 974  EMSMPLMET-MASGATSTLQTS-------VANSRSMSLSQTTYTVSGRMATAPIRASASG 1025
              SMP+  T +AS A STL T+       V NS     S TT   +    + P       
Sbjct: 2163 LTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEG---- 2218

Query: 1026 ARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGP-GTMS- 1083
              ST F    VS    +    +T S   +  S P  T+T++    T     S P  T+S 
Sbjct: 2219 --STPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE 2276

Query: 1084 --TPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPP 1135
              TP T+  V  T       + E ST       S +  T     T+ E + PPP
Sbjct: 2277 GTTPLTSIPVSHT----LVANSEVSTLSTTPVDSNTPFT-----TSTEASSPPP 2321



 Score =  124 bits (312), Expect = 5e-28
 Identities = 225/1013 (22%), Positives = 382/1013 (37%), Gaps = 110/1013 (10%)

Query: 33   TETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLM 92
            T T A          +P  + S      TS  +  +PV  + ++ L   P     + PL 
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDS--NTPLT 3254

Query: 93   PASDSGALSPLLMPASDSGALSPLLMPALDSGTLS--PLLSTSEYGVMSPGMMTIP-DFG 149
             ++++ +      P +  G   P   P+  S  L+  P+ +T+     +  + T P D  
Sbjct: 3255 TSTEASS-----SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTS 3309

Query: 150  TMSATLMVAPDSAEISP-LAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            T   T   A  S  I+   +MP  +     TP+ + S     ST  +++ ++  LS   +
Sbjct: 3310 TPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS----FSTTPVVSSEASTLSTTPV 3365

Query: 209  QDMNPGVMSTQPVPAPSS-EAMS-PLQITDEDTEAMSK--VLMTALASGEISSLLMSGTD 264
                P   ST+   +P++ E  S P     E T  ++   V  T + S E+++L  +  D
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVD 3425

Query: 265  SEAISSLIMSAVASG----GTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVM 320
            S  + +    A +S     GTS  PTST + G  P  +M                    +
Sbjct: 3426 SNTLVTTSTEASSSPTIAEGTS-LPTSTTSEGSTPLSIMP-------------------L 3465

Query: 321  STPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV 380
            ST  ++  +A  +ST P      +  +P   ++      PT + P        P ST   
Sbjct: 3466 STTPVASSEASTLSTTP-----VDTSTPVTTSS------PTNSSPTTAEVTSMPTSTAGE 3514

Query: 381  DSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTS 440
             S  ++N PV  T        PV + ++  +ST  + +      S+   + PA+  +TT 
Sbjct: 3515 GSTPLTNMPVSTT--------PVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTM 3566

Query: 441  LMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTP 500
             M+ PS G  S   M  +++ V         TS    T S  +V +     T++   STP
Sbjct: 3567 RMSTPSEGSSSLTTMLLSSTYV---------TSSEASTPSTPSVDRSTPVTTSTQSNSTP 3617

Query: 501  LRRAPTSGAMSTQPVTATASETM--SMPQLTVPASGSMSMLQM--RAPVSEAMSMPQMRT 556
                  +  MST    +T    M  S   +T+  +G+ S L +    PV  +  +     
Sbjct: 3618 TPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPV 3677

Query: 557  MASGLTSAAQMKAMTSGAMSTPLMTAQ------TSGSTSTLLMRDTASGVMSCPQMRSLA 610
               G T    M   T    STPL T        TS   STL    T S V S P   S  
Sbjct: 3678 TPEGTT----MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTL---STPSVVTSTPVTTSTE 3730

Query: 611  SGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASL 670
            + + S  L       T  +  M    S    T+L+  T       P+ +  +   +  S+
Sbjct: 3731 AISSSATL-----DSTTMSVSMPMEISTLGTTILVSTT--PVTRFPESSTPSIPSVYTSM 3783

Query: 671  MRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG 730
               TAS   S+     T+ G  +MP+    +   +  +++ + +S    S+  +   P G
Sbjct: 3784 SMTTASEGSSS---PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPG 3840

Query: 731  MSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSS 790
             + +P+ + T  G   + P        ++ +  S  ++T L+ T+ P   P      +S+
Sbjct: 3841 DTSTPLLTSTKAG-SFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPG--ASIAST 3897

Query: 791  GEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMT-ATASGMMSSMPQVKAPISGAMSMPL 849
              +       P++   +TP   P    +S   +T  +  G    +P      S A   P 
Sbjct: 3898 PPLDTSTTFTPSTDTASTP-TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPA 3956

Query: 850  TRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGT 909
            T    +G +S P++ + +    STS    T S    T     PA    ++PL     S  
Sbjct: 3957 T----TGAVSTPVITSTELNTPSTSSSSTTTSFS-TTKEFTTPAM-TTAAPLTYVTMSTA 4010

Query: 910  MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSA 969
             STP      C T S   + A+++ H ST+ TT  V+            S T+P     A
Sbjct: 4011 PSTPRTTSRGC-TTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPA 4069

Query: 970  MASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRAS 1022
             +S   +     T  +    T  T+     + + S  T T +       I+++
Sbjct: 4070 HSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSN 4122



 Score =  117 bits (293), Expect = 8e-26
 Identities = 232/994 (23%), Positives = 382/994 (38%), Gaps = 122/994 (12%)

Query: 207  LMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGE--ISSLLMSGTD 264
            L Q +  G  +       S+  + P       T      + +++ S    +SS  M+ T+
Sbjct: 55   LSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTE 114

Query: 265  SEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL 324
            S   S        S  T+  P+ST+++    TP  +D+         MS+P  E +S+ +
Sbjct: 115  SRTTSES-----TSDSTTLFPSSTEDTSSPTTPEGTDVP--------MSTPSEESISSTM 161

Query: 325  LSVPDAGEMSTLPKPAPDAEA-------MSPALMTALPSGVMPTQTMPAPGSGAMSPWST 377
              V      ST P P+ +A         MS  L T+  +   PT     P S  + P ST
Sbjct: 162  AFV------STAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPT----TPESTTI-PKST 210

Query: 378  QNVDSEMMSNPP-----VRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVP 432
             +  S  +++ P     V ++ +  +   PV       +S     +P +    +L  + P
Sbjct: 211  NSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAP 270

Query: 433  ASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRAT 492
            + G  +T L  +P S ++     ++T S   +A      TS    +    A       +T
Sbjct: 271  SGG--STPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTST 328

Query: 493  ASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMP 552
             + + STPL    TS   ST PV  +   T+S+  +      + S        +E  S+P
Sbjct: 329  YT-EGSTPL----TSTPASTMPVATSEMSTLSITPVDTSTLVTTS--------TEPSSLP 375

Query: 553  QMRTMASGLTSAAQ--MKAMTSGAMSTPLMTAQTSGSTSTLLMRD-----TASGVMSCPQ 605
                  S LTS        +T+  +ST L+ +  + +TST+ +       TAS   S P 
Sbjct: 376  TTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435

Query: 606  MRSLASGALSKPL--MTPKASGTMFTEKMTTTASEAMPTLLMRD-----TVSGALSMPQM 658
                 S A S P    TP  S  + T  + ++ +  + T  +       T + A S P  
Sbjct: 436  TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPT 495

Query: 659  TDTASGGLSASLMRDTASGAMSTSQM--TATVSGGMSMPLMRAQDPGVMPASLMRAKVSG 716
             +  S   S      T   +MS S M   ++ +  +S   +    P    +    +  + 
Sbjct: 496  AEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTP 555

Query: 717  KMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTP----TVRAWTSETMSTPL- 771
            +  S P ST   G   ++ M   T   + ++S  S   +TP    T    +SE  S+   
Sbjct: 556  EGTSIPTSTPSEGSTPLTNMPVSTR--LVVSSEASTTSTTPADSNTFVTTSSEASSSSTT 613

Query: 772  -----MRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRS--PAYGAMSAPQMT 824
                 M TS   ER + +T  S S  +   +  + AS    TP+ S  P   +  A   +
Sbjct: 614  AEGTSMPTSTYSERGTTITSMSVSTTL---VASSEASTLSTTPVDSNTPVTTSTEATSSS 670

Query: 825  ATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSR----VTSTSQMMPTA 880
             TA G            +   SMP+  +  +   +  L   P        TST       
Sbjct: 671  TTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPT 730

Query: 881  SGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMST-A 939
            + D  ++P   P+ G  S+PL   P S T+ T     S   T+ST  +  S     ST A
Sbjct: 731  TADGASMPTSTPSEG--STPLTSMPVSKTLLT----SSEASTLSTTPLDTSTHITTSTEA 784

Query: 940  QTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMET-MASGATSTLQTSVANS 998
              +   + G S P+   P+ G+   PL++       S+P+  T + S   STL T+  +S
Sbjct: 785  SCSPTTTEGTSMPI-STPSEGS---PLLT-------SIPVSITPVTSPEASTLSTTPVDS 833

Query: 999  RSMSLSQTTYTVSGRMAT-APIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMS 1057
             S   + T  + S   A    +  S      T      VS ++      +T S   +  S
Sbjct: 834  NSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTS 893

Query: 1058 MPQMTATDSRGMST----PLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINIT 1113
             P   +T++R   T      M  S PG  STP T+    +TP +    S EA T    ++
Sbjct: 894  TPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVV----SSEART----LS 945

Query: 1114 ASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPA 1147
            A+    ++ +T +T  T+ P   E  S    TP+
Sbjct: 946  ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS 979


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  142 bits (359), Expect = 2e-33
 Identities = 280/1227 (22%), Positives = 487/1227 (39%), Gaps = 200/1227 (16%)

Query: 31   PMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTM--SAPLMGVPNSGALS 88
            P+  T A          LP+ S S+   G T+   +TSP   +   + PL+    S A +
Sbjct: 1152 PLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSAST 1211

Query: 89   --PPLMPASDSGALS-------PLLMP-ASDSGALSPLLM---PALDSGTLSPLLSTSEY 135
                 +P +D+ ++S       P+ +P A+ +G  +PL +    +  +G  + LL T   
Sbjct: 1212 GHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTS 1271

Query: 136  GVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVV--CTPIMSTSSSEAMSTP 193
             V +     +P   T SA+      +  ++PL + +PSS      TP+  TS S A    
Sbjct: 1272 SVSTGDTTPLPVTSTSSAS------TGHVTPLHVTSPSSASTGHATPLPVTSLSSA---- 1321

Query: 194  LMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEA---MSPLQITDEDTEAMSKVLMTAL 250
                  +G+  P+             PV +PSS +    +PL +T  D  ++S    T L
Sbjct: 1322 -----STGDTMPL-------------PVTSPSSASTGDTTPLPVT--DASSVSTGHTTPL 1361

Query: 251  ASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSG--GIPTPLM----SDLDS 304
               + SS          ++SL  S+V++G T+P P ++ +S   G  TPL+    S   +
Sbjct: 1362 HVTDASSASTGQATPLPVTSL--SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSAST 1419

Query: 305  GIMSSLLMSSPGS----EVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTAL----PS 356
            G  + L ++   S       S P+     A    T P P  D  + S    T+L     S
Sbjct: 1420 GHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTS 1479

Query: 357  GVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLM 416
             V    T P P +   S  ST +V    +++P   + ++G  +  PV +L S +    + 
Sbjct: 1480 SVSTGDTTPLPVTSTSSA-STGHVTPLHVTSP--SSASTGHATPLPVTSLSSASTGDTMP 1536

Query: 417  GAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAM 476
                S + ++   T P      +S+ T  ++ +  T   SA+        +T   ++   
Sbjct: 1537 LPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKG 1596

Query: 477  PTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMS--TQPVTATASETMSMPQLTVPASG 534
             T  +   +     ++AS   +TPL    TS A +  T P+  T + ++S        +G
Sbjct: 1597 DTTPLPVTSP----SSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLS--------TG 1644

Query: 535  SMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPL--MTAQTSGSTSTLL 592
              + L + +P S +         A+ L   +   A T  A   P+  +++ T+  T+ L 
Sbjct: 1645 HATPLHVTSPSSASTG------HATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLP 1698

Query: 593  MRDTASG------VMSCPQMRSLASGALSK-PLMTPKASGT------MFTEKMTTTASEA 639
            + D +S        +    + S+++G  +  P+ +P ++ T      + T+  + +  +A
Sbjct: 1699 VTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQA 1758

Query: 640  MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRA 699
             P L + DT S  +S    T     GLS++   DT    ++     ++ S G ++PL   
Sbjct: 1759 TP-LPVTDTSS--VSTAHATPLPVTGLSSASTDDTTRLPVTD---VSSASTGQAIPL--- 1809

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMS-PMKSMTAGGMQMNSPTSDVMSTPT 758
              P   P+S      +   ++   S       S+   + S  + G   + P +D  S  T
Sbjct: 1810 --PVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVST 1867

Query: 759  VRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEI--------ATPL 810
              A +        + T D    P   T ++S+G+ + PL    AS            T L
Sbjct: 1868 GHATSLLVTDASSVSTGDTTPLPVTDTNSASTGD-TTPLHVTDASSVSTGHATSLPVTSL 1926

Query: 811  RSPAYGAMSAPQMT---ATASGMMSSMPQVKA---PISGAMSMPLT-RSTASGGMSMPL- 862
             S + G  +   +T   + +SG  + +P   A   P   A S+P+T  S+ S G + PL 
Sbjct: 1927 SSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLP 1986

Query: 863  --------------MRAPDSRVTSTSQMMP--------TASGDMCTLPV--RAPASGGVS 898
                          +   D+   ST Q  P         ++GD   LPV   + AS G  
Sbjct: 1987 VTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQD 2046

Query: 899  SPLVRAPASG-----TMSTPLRRPSACETVSTELMRASASGHMSTAQTTAM-------VS 946
            +PL     S      T   P+  PS+  T     +  + +  +ST   T++       VS
Sbjct: 2047 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVS 2106

Query: 947  GGMSKPLMRAPASG-----TMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSM 1001
             G +  L    AS      T P+P+ S       S    +T     T T   S  ++ S+
Sbjct: 2107 TGHATALHVTDASSLSTGDTTPLPVTS-----PSSASTGDTTPLPVTDTSSVSTGHATSL 2161

Query: 1002 SLSQTTYTVSGRMATAPI--RASASGARSTSFM---RASVSGSMPMPLPRATASGCGMGM 1056
             ++ T+   +G   + P+   +SAS   +T       +S S     PLP  + S    G 
Sbjct: 2162 PVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGH 2221

Query: 1057 SMPQM---TATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINIT 1113
            ++P +   T++ S G +TPL   S    +S+  T      T  +  TD+   ST H    
Sbjct: 2222 AIPLLVTDTSSASTGQATPLPVTS----LSSASTG----DTTPLPVTDASSVSTGH---- 2269

Query: 1114 ASGSKPTSHMTATTPETAKPPPKEVPS 1140
             + S P + +++ +     P P   PS
Sbjct: 2270 -ATSLPVTSLSSVSTGDTTPLPVTSPS 2295



 Score =  142 bits (359), Expect = 2e-33
 Identities = 303/1230 (24%), Positives = 485/1230 (39%), Gaps = 247/1230 (20%)

Query: 48   LPIVSTSASDPGGTSTQLMTS------------PVFDTMSAPL-----MGVPNSGALS-- 88
            LP+  TS++  G T+   +TS            PV DT SA       + V N+ +LS  
Sbjct: 1585 LPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTG 1644

Query: 89   --PPLMPASDS----GALSPLLMPASDS---GALSPLLMPALDSGTL--SPLLSTSEYGV 137
               PL   S S    G  +PL + ++ S   G  +PL +  L S T   +  L  ++   
Sbjct: 1645 HATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSS 1704

Query: 138  MSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSG--------------------VV 177
             S G  T      +  T + +  + + +PL + +PSS                       
Sbjct: 1705 ASTGQAT-----PLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQAT 1759

Query: 178  CTPIMSTSS-SEAMSTPLML-------APDSGELSPILMQDMNPGVMSTQPVPAPSSEA- 228
              P+  TSS S A +TPL +         D+  L    +   + G     PV +PSS + 
Sbjct: 1760 PLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAST 1819

Query: 229  --MSPLQITDE------DTEAMSKVLMTALASGEISSLLMSGTDSEAIS-----SLIM-- 273
               +PL +TD       DT ++   + ++ +SG  +SL +  TD+ ++S     SL++  
Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPV--TDASSVSTGHATSLLVTD 1877

Query: 274  -SAVASGGTSPQPTSTQNSG--GIPTPL----MSDLDSGIMSSL----LMSSPGSEVMST 322
             S+V++G T+P P +  NS   G  TPL     S + +G  +SL    L S+   +    
Sbjct: 1878 ASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPL 1937

Query: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPALMTALP----SGVMPTQTMPAPGSGAMSPWSTQ 378
            P+ S   A    T P P  DA ++     T+LP    S V      P P + A S     
Sbjct: 1938 PVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASS----- 1992

Query: 379  NVDSEMMSNPPVRATAS---GVMSAPPVRALDSGAM--STPLMGAPASGNMSTLQKTVP- 432
             V +   +  PV  T+S   G  +  PV +L S +   +TPL     S   +     +P 
Sbjct: 1993 -VSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPV 2051

Query: 433  ------ASGAMTTSLMTVPSSGVM--STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAV 484
                  ++G  T   +T PSS     +T  +   AS V +   T    + A    +  A 
Sbjct: 2052 TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHAT 2111

Query: 485  AKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAP 544
            A     A++       L    T+    T P +A+  +T  +P   V  + S+S       
Sbjct: 2112 ALHVTDASS-------LSTGDTTPLPVTSPSSASTGDTTPLP---VTDTSSVS------- 2154

Query: 545  VSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCP 604
               A S+P   T ++    A  +    + + ST        G  + L + DT+S      
Sbjct: 2155 TGHATSLPVTDTSSASTGHATSLPVTDTSSAST--------GHATPLPVTDTSS------ 2200

Query: 605  QMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASG 664
               +    A   P+ +P ++ T            A+P LL+ DT S   S  Q T     
Sbjct: 2201 ---ASTGQATPLPVTSPSSAST----------GHAIP-LLVTDTSSA--STGQATPLPVT 2244

Query: 665  GLSASLMRDTA------SGAMSTSQMT-------ATVSGGMSMPLMRAQDPGVMPASLMR 711
             LS++   DT       + ++ST   T       ++VS G + PL     P   P+S   
Sbjct: 2245 SLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPL-----PVTSPSSAST 2299

Query: 712  AKVSGKMLSQPMSTQDPGGMSMSPMKSMTAG--GMQMNSPTSDVMSTPTVRAWTSETMST 769
               +   ++   S+   G  +  P+ S+++   G     P +   S  T  A        
Sbjct: 2300 GHATPLHVTD-ASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDA 2358

Query: 770  PLMRTSDPGERPSLLTRASSSGEMS-LPLMRA-PASGEIATPLRSPAYGAMSAPQMTAT- 826
              + T D    P   + ++SSG  + LP+  A  AS    TPL  P     SA    AT 
Sbjct: 2359 SSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPL--PVTDTSSASTGHATH 2416

Query: 827  --ASGMMSSMPQVKAPISGAMSMPLTR-STASGGMSMPLMRAPDSRVTSTSQMMPTASGD 883
               +G+ S      A       +P+T  S+AS G + PL       VTSTS     ++GD
Sbjct: 2417 LPVTGLSS------ASTGDTTRLPVTNVSSASTGHATPL------PVTSTSS---ASTGD 2461

Query: 884  MCTLP--VRAPASGGVSSPLVRAPASG-----TMSTPLRRPSACETVSTELMRASASGHM 936
               LP    +  S G ++PL+   AS      T   P+  PS+  T  T  +  + +   
Sbjct: 2462 TTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSA 2521

Query: 937  STAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASG--------AT 988
            ST  TT +     S    R   S  +  P  SA      S+P+ +T A+          T
Sbjct: 2522 STGDTTPLPVTNASSLSTRHATSLHVTSP-SSASTGHATSLPVTDTSAASTGHATPLPVT 2580

Query: 989  STLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRAT 1048
            ST   S  ++  + ++ T    +G+    P+  ++S         AS   + P+P+   +
Sbjct: 2581 STSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSS---------ASTGDTTPLPVTDTS 2631

Query: 1049 ASGCGMGMSMP-QMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEAST 1107
            ++  G    +P   T++ S G +TPL   + P + ST  T      TP +  TD+   ST
Sbjct: 2632 SASTGHATPLPVTNTSSVSTGHATPL-HVTSPSSASTGHT------TP-LPVTDASSVST 2683

Query: 1108 SH---INITASGSKPTSHMTA---TTPETA 1131
             H   + +T + S  T H T+   T P +A
Sbjct: 2684 GHATSLPVTDASSVFTGHATSLPVTIPSSA 2713



 Score =  138 bits (348), Expect = 3e-32
 Identities = 285/1186 (24%), Positives = 485/1186 (40%), Gaps = 223/1186 (18%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTM--SAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            LP+ STS++  G  +   +TSP   +   + PL     S A +   MP        P+  
Sbjct: 1281 LPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL-------PVTS 1333

Query: 106  PASDS-GALSPLLMPALDSGTLS----PLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
            P+S S G  +PL  P  D+ ++S      L  ++    S G  T      +  T + +  
Sbjct: 1334 PSSASTGDTTPL--PVTDASSVSTGHTTPLHVTDASSASTGQAT-----PLPVTSLSSVS 1386

Query: 161  SAEISPLAMPAPSSGVV--CTPIMSTSSSEAMSTPLMLAPDSGELSPILMQD---MNPGV 215
            + + +PL + +PSS      TP++ T +S A          +G  +P+ + D   ++   
Sbjct: 1387 TGDTTPLPVTSPSSASTGHATPLLVTDTSSA---------STGHATPLPVTDASSVSTDH 1437

Query: 216  MSTQPVPAPSSEA---MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLI 272
             ++ PV  PS+ +    +PL +TD           ++ ++G+ +SLL++ T         
Sbjct: 1438 ATSLPVTIPSAASTGHTTPLPVTD----------TSSASTGQATSLLVTDT--------- 1478

Query: 273  MSAVASGGTSPQP-TSTQN-SGGIPTPL----MSDLDSGIMSSL----LMSSPGSEVMST 322
             S+V++G T+P P TST + S G  TPL     S   +G  + L    L S+   + M  
Sbjct: 1479 -SSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL 1537

Query: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPALMTAL----PSGVMPTQTMPAPGSGAMSPWSTQ 378
            P+ S   A    T P P  DA ++S    T L    PS      T P P +      S  
Sbjct: 1538 PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTS---SAS 1594

Query: 379  NVDSEMMSNPPVRATASGVMSAPPVRALDSGAM--STPLMGAPAS----GNMSTLQKTVP 432
              D+  +      + ++G  +  PV    S +   +TPL    AS    G+ + L  T P
Sbjct: 1595 KGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP 1654

Query: 433  ASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRAT 492
            +S A T     +P +   S     AT   V          +  +P   +         ++
Sbjct: 1655 SS-ASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDV---------SS 1704

Query: 493  ASGKMSTPL----RRAPTSGAMSTQPVT--ATASETMSMPQLTVPASGSMSMLQMRAPVS 546
            AS   +TPL      + ++G  +  PVT  ++AS   + P L   AS + +      PV+
Sbjct: 1705 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVT 1764

Query: 547  EAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPL-MTAQTSGSTSTLLMRDTASGVMSCPQ 605
            +  S+                    S A +TPL +T  +S ST      DT    +    
Sbjct: 1765 DTSSV--------------------STAHATPLPVTGLSSASTD-----DTTR--LPVTD 1797

Query: 606  MRSLASG-ALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASG 664
            + S ++G A+  P+ +P ++ T  T  +  T + +  T    DT S  +++P    +AS 
Sbjct: 1798 VSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSAST---GDTTSLPVTIP---SSASS 1851

Query: 665  GLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMS 724
            G + SL    AS ++ST   T+ +    S   +   D   +P +   +  +G   + P+ 
Sbjct: 1852 GHTTSLPVTDAS-SVSTGHATSLLVTDASS--VSTGDTTPLPVTDTNSASTGD--TTPLH 1906

Query: 725  TQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTP-TVRAWTSETMSTPLMRTS----DPGE 779
              D   +S     S+    +  ++ T D    P T  +  S   +TPL  T       G 
Sbjct: 1907 VTDASSVSTGHATSLPVTSLS-SASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGH 1965

Query: 780  RPSL-LTRASS-SGEMSLPLMRAPASGEI---ATPLRSPAYGAMSAPQMTATASGMMSSM 834
              SL +T ASS S   + PL    AS      ATPL      ++S  Q T      +SS 
Sbjct: 1966 ATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSS- 2024

Query: 835  PQVKAPISGAMSMPLT-RSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAP- 892
                A       +P+T  S+AS G   PL       VTS S +   ++GD   LPV +P 
Sbjct: 2025 ----ASTGDTTPLPVTDTSSASTGQDTPL------PVTSLSSV---STGDTTPLPVTSPS 2071

Query: 893  -ASGGVSSPLVRAPASG-----TMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVS 946
             AS G ++PL+   AS        S  +   S+  T     +  + +  +ST  TT +  
Sbjct: 2072 SASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPV 2131

Query: 947  GGMSKPLMRAPASGTMPMPL--MSAMASGE-MSMPLMETMASG--------ATSTLQTSV 995
               S     A    T P+P+   S++++G   S+P+ +T ++          T T   S 
Sbjct: 2132 TSPSS----ASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSAST 2187

Query: 996  ANSRSMSLSQTTYTVSGRMATAPIRASASGARS-----------------------TSFM 1032
             ++  + ++ T+   +G+    P+ + +S +                         TS  
Sbjct: 2188 GHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLS 2247

Query: 1033 RASVSGSMPMPLPRATASGCGMGMSMPQMTATD-SRGMSTPLMRASGPGTMSTPQTAFGV 1091
             AS   + P+P+  A++   G   S+P  + +  S G +TPL        +++P +A   
Sbjct: 2248 SASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPL-------PVTSPSSASTG 2300

Query: 1092 MSTPEIKATDSGEASTSH------INITASGSKPTSHMTATTPETA 1131
             +TP +  TD+  AST H       +++++ +  T+ +  T+P +A
Sbjct: 2301 HATP-LHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSA 2345



 Score =  134 bits (337), Expect = 6e-31
 Identities = 291/1298 (22%), Positives = 503/1298 (38%), Gaps = 250/1298 (19%)

Query: 5    LHSLRFNNTMREENVEPQNKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQ 64
            L S+   +T       P +       P+  T A          LP+ S S++  G T+  
Sbjct: 2278 LSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPL 2337

Query: 65   LMTSP-VFDTMSAPLMGVPNSGALS----PPLMPASDSGALS--PLLMPASDSGALSPLL 117
             +TSP    T  A  + V ++ ++S     PL   S S A S     +P +D+ + S   
Sbjct: 2338 PVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSAS--- 2394

Query: 118  MPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSG-V 176
                 +G  +PL  T      +     +P  G  SA+     D+  +    + + S+G  
Sbjct: 2395 -----TGDTTPLPVTDTSSASTGHATHLPVTGLSSAS---TGDTTRLPVTNVSSASTGHA 2446

Query: 177  VCTPIMSTSSSEAMSTPLMLAPD-----SGELSPILMQD---MNPGVMSTQPVPAPSSEA 228
               P+ STSS+    T  +   D     +G  +P+L+ D   ++ G  +  PV +PSS +
Sbjct: 2447 TPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSAS 2506

Query: 229  ---MSPLQITDE------DTEAMSKVLMTALASGEISSLLMSG--------------TDS 265
                +PL +TD       DT  +     ++L++   +SL ++               TD+
Sbjct: 2507 TGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDT 2566

Query: 266  EAISS--------LIMSAVASGGTSPQP-------------------TSTQNSG------ 292
             A S+           S+ ++G T+P P                   TS+ ++G      
Sbjct: 2567 SAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLP 2626

Query: 293  ---------GIPTPL----MSDLDSGIMSSLLMSSPGS-EVMSTPLLSVPDAGEMST--- 335
                     G  TPL     S + +G  + L ++SP S     T  L V DA  +ST   
Sbjct: 2627 VTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHA 2686

Query: 336  LPKPAPDAEAM----SPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVR 391
               P  DA ++    + +L   +PS      T P P + A S  +         S P   
Sbjct: 2687 TSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVST-----GHATSLPVTD 2741

Query: 392  ATASGVMSAPPVRALDSGAMS----TPL----MGAPASGNMSTLQKTVPASGAMTTSLMT 443
            A++     A P+   D+ ++S    TPL    + + ++G+ + L  T   S A T     
Sbjct: 2742 ASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVT-DTSSASTGQATP 2800

Query: 444  VPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRR 503
            +P + + S      T   V          + ++P             ++AS   +TPL  
Sbjct: 2801 LPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTD---------TSSASTGHATPLPD 2851

Query: 504  APTSGAMSTQ----PVTATASETM----SMP--QLTVPASGSMSMLQMRAPVS----EAM 549
              TS A +      PVT T+S ++    S+P    +  ++G  + L + +P S     A 
Sbjct: 2852 TDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHAT 2911

Query: 550  SMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASG------VMSC 603
             +P   T ++    A  +   +  + ST        G  + L + DT+S        +  
Sbjct: 2912 PLPVTDTSSASTGHANPLHVTSPSSAST--------GHATPLPVTDTSSASTGHATPLPV 2963

Query: 604  PQMRSLASGALSK-PLMTPKASGTMFTEKM--------TTTASEAMPTLLMRDTVSGALS 654
              + S+++G  +  P+ +P ++ T  T  +        +T  + A+P        +G  +
Sbjct: 2964 TSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTT 3023

Query: 655  MPQMTDTASGGL-SASLMRDTASGAMSTSQMT-------ATVSGGMSMPLMRAQDPGV-- 704
               +TDT+S     A+ +  T+  ++ST   T       ++ S G + PL+         
Sbjct: 3024 PLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSAST 3083

Query: 705  -----MPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
                 +P + + +  +G     P+++        +    +T         T+ +  T T 
Sbjct: 3084 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTS 3143

Query: 760  RAWTSETMSTPLMRTSDPG---ERPSLLTRASS-SGEMSLPLMRAPASGEI---ATPLRS 812
             A+T +T S P+  TS        P L+T  SS S   + PL+   AS      ATPL  
Sbjct: 3144 SAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHV 3203

Query: 813  PAYGAMSAPQMT---ATASGMMSSMPQVKAPISGAMS--------MPLTR-STASGGMSM 860
             +  + S    T    T +  +S+      P++G  S        +P+T  S+AS G + 
Sbjct: 3204 TSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQAT 3263

Query: 861  PLMRAPDSRVTSTSQMMPTASGDMCTLPVRAP--ASGGVSSPLVRAPASGTMSTPLRRPS 918
            PL       VT+TS +   ++GD   LPV +P  AS G ++PL   P + T S      +
Sbjct: 3264 PL------PVTNTSSV---STGDTMPLPVTSPSSASTGHATPL---PVTSTSSASTGHAT 3311

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMS-AMASGEMSM 977
                 ST    ++++GH +    T   S         A    T P+P+ S + AS   + 
Sbjct: 3312 PVPVTSTS---SASTGHTTPLPVTDTSS---------ASTGDTTPLPVTSPSSASTGHTT 3359

Query: 978  PLMETMAS----GATSTLQTSVANSRS------MSLSQTTYTVSGRMATAPIRASASGAR 1027
            PL  T+ S    G TSTL  + A+S S      + ++ T+   +G     P+        
Sbjct: 3360 PLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPV-------- 3411

Query: 1028 STSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATD-SRGMSTPLMRASGPGTMSTPQ 1086
             TS    S   + P+P+  A+++  G    +P  + +  S G +TPL+        +   
Sbjct: 3412 -TSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3470

Query: 1087 TAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMT 1124
            T   V  T      D     T+ + +T + S  T   T
Sbjct: 3471 TPLPVTDTSSASTGD-----TTRLPVTDTSSASTGQAT 3503



 Score =  130 bits (326), Expect = 1e-29
 Identities = 313/1338 (23%), Positives = 515/1338 (38%), Gaps = 265/1338 (19%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTM--SAPL-----MGVPNSGALSPPLMPASDSGAL 100
            LP+ S S++  G T+   +TSP   +   + PL       VP   A S P+  AS     
Sbjct: 1921 LPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTG 1980

Query: 101  SPLLMPASDSGALSP---LLMPALDSGTLS-----PLLSTSEYGVMSPGMMTIPDFGTMS 152
                +P +D+ ++S      +P  D+ ++S     PL  TS     +     +P   T S
Sbjct: 1981 HATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSS 2040

Query: 153  A----------TLMVAPDSAEISPLAMPAPSSGVV--CTPIMSTSSSEAMS---TPLMLA 197
            A          T + +  + + +PL + +PSS      TP++ T +S   +   T L++ 
Sbjct: 2041 ASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVT 2100

Query: 198  PDS----GELSPILMQD---MNPGVMSTQPVPAPSSEAM---SPLQITDEDTEAMSKVLM 247
              S    G  + + + D   ++ G  +  PV +PSS +    +PL +TD  T ++S    
Sbjct: 2101 DASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTD--TSSVSTGHA 2158

Query: 248  TALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSG--GIPTPLM----SD 301
            T+L   + SS       S  ++    S+ ++G  +P P +  +S   G  TPL     S 
Sbjct: 2159 TSLPVTDTSSASTGHATSLPVTDT--SSASTGHATPLPVTDTSSASTGQATPLPVTSPSS 2216

Query: 302  LDSGIMSSLLMSSPGS----EVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALP-- 355
              +G    LL++   S    +    P+ S+  A    T P P  DA ++S    T+LP  
Sbjct: 2217 ASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVT 2276

Query: 356  --SGVMPTQTMPAP-----------------------GSGAMSPWSTQNVDSEMMSN--- 387
              S V    T P P                        +G  +P    ++ S    +   
Sbjct: 2277 SLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTP 2336

Query: 388  -PPVRATASGVMSAPPVRALDSGAMS----TPL---MGAPASGNMSTLQKTVPASGAMTT 439
             P    +++    A P+   D+ ++S    TPL     + AS   +T      AS A T 
Sbjct: 2337 LPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTG 2396

Query: 440  SLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQY-------KRAT 492
                +P +   S     AT   V          +  +P  ++ + +  +         ++
Sbjct: 2397 DTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSS 2456

Query: 493  ASGKMSTPLRRAPTSGAMS------------------------TQPVTATASETMSMPQL 528
            AS   +TPL    TS   +                        T P +A+   T  +P  
Sbjct: 2457 ASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVT 2516

Query: 529  TVPASG----------SMSMLQMR------------APVSEAMSMPQMRTMASGLTSAAQ 566
              P++           + S L  R            A    A S+P   T A+    A  
Sbjct: 2517 DTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATP 2576

Query: 567  MKAMTSGAMS--------------------TPLMTAQTS----GSTSTLLMRDTASG--- 599
            +   ++ + S                    TPL    TS    G T+ L + DT+S    
Sbjct: 2577 LPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTG 2636

Query: 600  ---VMSCPQMRSLASG-ALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSM 655
                +      S+++G A    + +P ++ T  T  +  T + ++ T         A S+
Sbjct: 2637 HATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVST-------GHATSL 2689

Query: 656  PQMTDTAS--GGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAK 713
            P +TD +S   G + SL     S A S       V+   S+    A    V  AS +   
Sbjct: 2690 P-VTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTG 2748

Query: 714  VSGKMLSQPMSTQDPGGMSMSPMKSMT--AGGMQMNSPTSDVMSTPTVRAWTSETMSTPL 771
             +  +     S+   G  +  P+ S++  + G     P +D  S  T +A      S   
Sbjct: 2749 HATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSS 2808

Query: 772  MRTSDPGERPSLLTRASSSGE-MSLPLM-RAPASGEIATPL-----RSPAYGAMSAPQMT 824
            + T D    P   T ++S+G   SLP+   + AS   ATPL      S + G  +   +T
Sbjct: 2809 VSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVT 2868

Query: 825  ATAS---GMMSSMP---------------QVKAPISG----AMSMPLT-RSTASGGMSMP 861
             T+S   G  +S+P                V +P S     A  +P+T  S+AS G + P
Sbjct: 2869 DTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANP 2928

Query: 862  L-MRAPDSRVTSTSQMMP------TASGDMCTLPVR--APASGGVSSPL-VRAPASG--- 908
            L + +P S  T  +  +P       ++G    LPV   +  S G ++PL V +P+S    
Sbjct: 2929 LHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 2988

Query: 909  -TMSTPLRRPSACETVSTELMRASASGHMSTAQTTAM-------VSGGMSKPLMRAPASG 960
             T   P+   S+  T     +  +++   ST  TT +        S G + PL     S 
Sbjct: 2989 HTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS 3048

Query: 961  -----TMPMPLMS-AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRM 1014
                 T P+P+ S + AS   + PL+ T AS A ST Q +     S+S S +T   +   
Sbjct: 3049 VSTGDTTPLPVTSPSSASTGHATPLLVTDASSA-STGQATPLPVTSLS-SVSTGDTTPLP 3106

Query: 1015 ATAPIRASASGARS---TSFMRASVSGSMPMPLPRATASGCGMGMSMPQM-TATDSRGMS 1070
             T+P  AS   A S   T    AS   +  +P+   +++  G   S+P   T++ S G +
Sbjct: 3107 VTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDT 3166

Query: 1071 TPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPET 1130
            TPL+  +   ++ST        +TP +  TD+  AST H    A+    TS  +A+T +T
Sbjct: 3167 TPLL-VTETSSVSTGH------ATP-LLVTDASSASTGH----ATPLHVTSPSSASTGDT 3214

Query: 1131 AKPPPKEVPSF--GMLTP 1146
               P  +  S   G  TP
Sbjct: 3215 TPVPVTDTSSVSTGHATP 3232



 Score =  126 bits (316), Expect = 2e-28
 Identities = 273/1227 (22%), Positives = 485/1227 (39%), Gaps = 186/1227 (15%)

Query: 31   PMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPP 90
            P+T+T A     H+   LP+ STS++  G T+      PV DT SA      ++G  +P 
Sbjct: 2562 PVTDTSA-ASTGHA-TPLPVTSTSSASTGDTTPL----PVTDTYSA------STGQATP- 2608

Query: 91   LMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLS-------PLLSTSEY--GVMSPG 141
             +P +D+ + S        +G  +PL  P  D+ + S       P+ +TS    G  +P 
Sbjct: 2609 -LPVTDTSSAS--------TGDTTPL--PVTDTSSASTGHATPLPVTNTSSVSTGHATPL 2657

Query: 142  MMTIPDFG-TMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLML--AP 198
             +T P    T   T +   D++ +S       ++ +  T   S  +  A S P+ +  + 
Sbjct: 2658 HVTSPSSASTGHTTPLPVTDASSVST----GHATSLPVTDASSVFTGHATSLPVTIPSSA 2713

Query: 199  DSGELSPILMQD---MNPGVMSTQPVPAPSSEAM---SPLQITDEDTEAMSKVL------ 246
             SG  +P+ + D   ++ G  ++ PV   SS +    +PL +TD  + +           
Sbjct: 2714 SSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTS 2773

Query: 247  MTALASGEISSLLMSGTDSEAISSLI------MSAVASGGTSPQPT------STQNSGGI 294
            ++++++G+ + L ++ T S +           +S+V++G T+P P       ST ++  +
Sbjct: 2774 LSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSL 2833

Query: 295  PTPLMSDLDSGIMSSLLMSSPGSEVMS-TPLLSVPDAGEMS---TLPKPAPDAEAMSPAL 350
            P    S   +G  + L  +   S       LL V D    S       P  D  ++S   
Sbjct: 2834 PVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGH 2893

Query: 351  MTAL----PSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRAL 406
             T L    PS        P P +   S  ST + +   +++P   +T      A P+   
Sbjct: 2894 ATPLHVTSPSSASTGHATPLPVTDTSSA-STGHANPLHVTSPSSASTGH----ATPLPVT 2948

Query: 407  DSGAMST----PL----MGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSAT 458
            D+ + ST    PL    + + ++G+ + L  T P+S A T     +P +   S     AT
Sbjct: 2949 DTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSS-ASTGHTTPLPVTDTSSASTGQAT 3007

Query: 459  ASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLR----RAPTSGAMSTQP 514
            A  V S        +  +P             ++AS   +TPL      + ++G  +  P
Sbjct: 3008 ALPVTSTSSASTGDTTPLPVTDT---------SSASTGQATPLPVTSLSSVSTGDTTPLP 3058

Query: 515  VTA--TASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTS 572
            VT+  +AS   + P L   AS + +      PV+   S+    T    +TS +   A T 
Sbjct: 3059 VTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS--ASTG 3116

Query: 573  GAMSTPLM--TAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTE 630
             A S P+   ++ ++G T++L + DT+S         +      S P+    +S T  T 
Sbjct: 3117 HATSLPVTDTSSASTGDTTSLPVTDTSS---------AYTGDTTSLPVTDTSSSSTGDTT 3167

Query: 631  KMTTTASEAMPT-----LLMRDTVSGA------LSMPQMTDTASGGLSASLMRDTASGAM 679
             +  T + ++ T     LL+ D  S +      L +   +  ++G  +   + DT+S  +
Sbjct: 3168 PLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSS--V 3225

Query: 680  STSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPM---STQDPGGMSMSPM 736
            ST   T     G+S       D   +P + + +  +G+    P+   S+   G     P+
Sbjct: 3226 STGHATPLPVTGLSS--ASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPV 3283

Query: 737  KSMTAG--GMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMS 794
             S ++   G     P +   S  T  A      ST    T      P   T ++S+G+ +
Sbjct: 3284 TSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTT 3343

Query: 795  LPLMRAPASGEI--ATPLR-----SPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSM 847
               + +P+S      TPL      S + G  S   +T  +S   S+      P++   S+
Sbjct: 3344 PLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSA--STGHATPLPVTDTSSV 3401

Query: 848  PLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVR--APASGGVSSPLVRAP 905
                +T     S+  +   D+     +     ++G    LPV   +  S G ++PL+   
Sbjct: 3402 STGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTD 3461

Query: 906  ASGTMS-----TPLRRPSACETVSTELMRASASGHMSTAQTTAM-------VSGGMSKPL 953
            AS   +      P+   S+  T  T  +  + +   ST Q T +       VS G + PL
Sbjct: 3462 ASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL 3521

Query: 954  MRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTT------ 1007
            +   AS        S        +P+ +T ++    T +  V ++ S S  Q T      
Sbjct: 3522 LVTDAS--------SVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTI 3573

Query: 1008 YTVSGRMATAPIRASASGARSTSFMR-------ASVSGSMPMPLPRATASGCGMGMSMPQ 1060
             + S    T P+  +++ + ST  +        +S S     PLP  + S    G + P 
Sbjct: 3574 PSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATP- 3632

Query: 1061 MTATDSRGMST------PLMRASGPGT-MSTPQTAFGVMSTPEIKATDSGEASTSHINIT 1113
            +  TD+  +ST      P+  AS   T  +TP       S    +AT     S S ++  
Sbjct: 3633 LLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTG 3692

Query: 1114 ASGSKPTSHMTATTPETAKPPPKEVPS 1140
             +   P +  ++ +   A P P  +PS
Sbjct: 3693 DTTPLPVTDASSASTGHATPLPVTIPS 3719



 Score =  120 bits (301), Expect = 9e-27
 Identities = 278/1217 (22%), Positives = 469/1217 (38%), Gaps = 225/1217 (18%)

Query: 55   ASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALS 114
            +S+P   S    ++    + SA    +P S  ++  ++P    G   P L  AS +G   
Sbjct: 831  SSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVP----GTFHPTLSEASTAGR-- 884

Query: 115  PLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTM-SATLMVAPDSAEISPLAMPAPS 173
                P   S   SP  S  E   +S    T     +  S T+ +A  + +      P P 
Sbjct: 885  ----PTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPP 940

Query: 174  SGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQ 233
            S      I ST  +   +    L+P     +       N   +      + S+   +PL 
Sbjct: 941  S------ITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLH 994

Query: 234  ITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQP---TSTQN 290
            +TD           +++++G  + L ++            S+V++G T+P P   TS+++
Sbjct: 995  VTDA----------SSVSTGHATPLPVTSP----------SSVSTGHTTPLPVTDTSSES 1034

Query: 291  SGGI---PTPLMSDLDSGIMSSLLMSSPGS----EVMSTPLLSVPDAGEMSTLPKPAPDA 343
            +G +   P    S   +G  + L ++   S     V   P+ S+  A    T P P  D 
Sbjct: 1035 TGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDT 1094

Query: 344  EAMSPALMTALP----SGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATAS-GVM 398
             + S    T+LP    S V    T P P +       T +  +   ++ PV  T+S    
Sbjct: 1095 SSASTGHATSLPVTDTSSVSTGHTTPLPVT------DTSSASTGHATSLPVTDTSSVSTG 1148

Query: 399  SAPPVRALDSGAMS----TPL----MGAPASGNMSTLQKTVPASGAM----------TTS 440
               P+   D+ + S    TPL    + + ++G+ + L  T P+S +           T+S
Sbjct: 1149 HTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSS 1208

Query: 441  LMTVPSSGVMSTEQMSATASRVMSAQLTM---AKTSGAMP----------TGSMKAVAKQ 487
              T  ++ +  T+  S +     S  +T+   A T    P          TG   ++   
Sbjct: 1209 ASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVT 1268

Query: 488  YKRATASGKMSTPLRRAPTSGAMSTQ--------------------PVT----ATASETM 523
               + ++G  +TPL    TS A +                      PVT    A+  +TM
Sbjct: 1269 DTSSVSTGD-TTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTM 1327

Query: 524  SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK------------AMT 571
             +P +T P+S S        PV++A S+    T    +T A+               +  
Sbjct: 1328 PLP-VTSPSSASTGD-TTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSV 1385

Query: 572  SGAMSTPL-MTAQTSGST---STLLMRDTASGVM--SCPQMRSLASG-----ALSKPLMT 620
            S   +TPL +T+ +S ST   + LL+ DT+S     + P   + AS      A S P+  
Sbjct: 1386 STGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTI 1445

Query: 621  PKASGTMFTEKMTTTASEAMPT-----LLMRDTVS---GALSMPQMTDTASGGLS-ASLM 671
            P A+ T  T  +  T + +  T     LL+ DT S   G  +   +T T+S      + +
Sbjct: 1446 PSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPL 1505

Query: 672  RDTASGAMSTSQMT-------ATVSGGMSMPL-------MRAQDPGVMPASLMRAKVSGK 717
              T+  + ST   T       ++ S G +MPL           D   +P +   +  +G 
Sbjct: 1506 HVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGH 1565

Query: 718  MLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDP 777
                P+++        +    +T         T+ +  T    A T  T   P+  TS  
Sbjct: 1566 TTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSS- 1624

Query: 778  GERPSLLTRASSSGEMSLPLMRAPA-SGEIATPLRSPAYGAMS---APQMTATASGMMSS 833
                     AS+     LP+  A + S   ATPL   +  + S   A  +  T++   S+
Sbjct: 1625 ---------ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSAST 1675

Query: 834  MPQVKAPISGAMS--------MPLTR-STASGGMSMPLMRAPDSRVTSTSQMMPTASGDM 884
                  P++G  S        +P+T  S+AS G + PL       VTS S +   ++GD 
Sbjct: 1676 GHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPL------PVTSLSSV---STGDT 1726

Query: 885  CTLPVRAP--ASGGVSSPLVRAPASGTMS-----TPLRRPSACETVSTELMRASASGHMS 937
              LPV +P  AS G +SPL+   AS   +      P+   S+  T     +  +     S
Sbjct: 1727 TPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSAS 1786

Query: 938  TAQTTAMVSGGMSKPLMRAPASGTMPMPLMS-AMASGEMSMPLMETMASGATSTLQTSVA 996
            T  TT +    +S     A     +P+P+ S + AS   + PL  T AS A      S  
Sbjct: 1787 TDDTTRLPVTDVSS----ASTGQAIPLPVTSPSSASTGDTTPLPVTDASSA------STG 1836

Query: 997  NSRSMSLSQTTYTVSGRMATAPI--RASASGARSTSFM---RASVSGSMPMPLPRATASG 1051
            ++ S+ ++  +   SG   + P+   +S S   +TS +    +SVS     PLP    + 
Sbjct: 1837 DTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNS 1896

Query: 1052 CGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSH-- 1109
               G + P +  TD+  +ST    +    ++S+  T      T  +  T    AS+ H  
Sbjct: 1897 ASTGDTTP-LHVTDASSVSTGHATSLPVTSLSSASTG----DTTPLPVTSPSSASSGHTT 1951

Query: 1110 -INITASGSKPTSHMTA 1125
             + +T + S PT H T+
Sbjct: 1952 PLPVTDASSVPTGHATS 1968



 Score =  108 bits (269), Expect = 5e-23
 Identities = 264/1086 (24%), Positives = 435/1086 (40%), Gaps = 214/1086 (19%)

Query: 48   LPIVSTSASDPGGTSTQLMT--SPVFDTMSAPLMGVPNSGALSPPLMP-------ASDSG 98
            LP+  TS+S  G T+  L+T  S V    + PL+    S A +    P       ++ +G
Sbjct: 3153 LPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTG 3212

Query: 99   ALSPLLMPASDSGALS-----PLLMPALDSGTLSPL--LSTSEYGVMSPGMMT-IPDFGT 150
              +P+  P +D+ ++S     PL +  L S +      L  ++    S G  T +P   T
Sbjct: 3213 DTTPV--PVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNT 3270

Query: 151  MSATLMVAPDSAEISPLAMPAPSSGVV--CTPIMSTSSSEAMS---TPLMLAPDS----G 201
             S +      + +  PL + +PSS      TP+  TS+S A +   TP+ +   S    G
Sbjct: 3271 SSVS------TGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTG 3324

Query: 202  ELSPILMQDMNP---GVMSTQPVPAPSSEAM---SPLQIT------DEDTEAMSKVLMTA 249
              +P+ + D +    G  +  PV +PSS +    +PL +T        DT  +     ++
Sbjct: 3325 HTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASS 3384

Query: 250  LASGEISSLLMSGTDSEAISSLI------MSAVASGGTSPQPTSTQNSG--GIPTPLMSD 301
             ++G  + L ++ T S +           +S+V++G T+P P +  +S   G  TPL   
Sbjct: 3385 ASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLP-- 3442

Query: 302  LDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMST---LPKPAPDAEAMSPALMTALP--- 355
                 ++SL   S G    +TPLL V DA  +ST    P P  D  + S    T LP   
Sbjct: 3443 -----VTSLSSVSTGD---TTPLL-VTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTD 3493

Query: 356  -SGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMST- 413
             S     Q  P P + ++S  ST +    ++++    A++     A P+   D+ + ST 
Sbjct: 3494 TSSASTGQATPLPVT-SLSSVSTGDTTPLLVTD----ASSVSTGHATPLPVTDTSSASTG 3548

Query: 414  -----PLM--GAPASGNMSTLQKTVPASGAM--TTSLMTVPSSGVMS--------TEQMS 456
                 P+    + ++G  + L  T+P+S +   TT L    +S V +        T   S
Sbjct: 3549 DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSS 3608

Query: 457  ATASRVMSAQLTM---AKTSGAMPTGSMKAVAKQYKRAT---------ASGKMSTPLRRA 504
            A+   V    +T    A T  A P     A +     AT         AS   +TPL   
Sbjct: 3609 ASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVT 3668

Query: 505  PTSGAMSTQ----PVTATASETM--SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMA 558
             TS A + Q    PVT+ +S +   + P     AS + +      PV+   S+    TM 
Sbjct: 3669 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMP 3728

Query: 559  SGLTSAAQMKAMTSGAMSTPL--MTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSK 616
              +TS +   A T  A   P+  +++ ++G T+ L + DT+S           AS   + 
Sbjct: 3729 LPVTSPSS--ASTGHATPLPVTGLSSASTGDTTPLPVTDTSS-----------ASTRHAT 3775

Query: 617  PLM---TPKASGTMFTEKMTTTASEA-------MPTLLMRDTVSGALSMPQMTDTASGGL 666
            PL    T  AS    T    T  S A       +P        +G  +   +TDT+S   
Sbjct: 3776 PLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVST 3835

Query: 667  S-ASLMRDTASGAMSTSQMT-------ATVSGGMSMPLMRAQDPGV-------MPASLMR 711
              A+ +  T+  + ST   T       ++VS G + PL       V       +P +   
Sbjct: 3836 GHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPS 3895

Query: 712  AKVSGKMLSQPM------STQDPGGMSMSPMKSMTAGG---MQMNSPTS----DVMSTPT 758
            +  +G     P+      ST D   + ++   S++ G    + + SP+S    D  + P 
Sbjct: 3896 SASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPV 3955

Query: 759  VRAWTSET-MSTPLMRTSDPGERPSLLTRASSSGEMSLPLM-RAPASGEIATPLRSPAYG 816
              A ++ T  +TPL  TS        L+  S+     LP+   + AS   ATPL   +  
Sbjct: 3956 TDASSASTGHATPLPLTS--------LSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 4007

Query: 817  AMSAPQMT--------ATASGMMSSMPQVKAP-ISGAMSMPL---TRSTASGGMSMPLMR 864
            ++S    T        + +SG  +S+P   A  +S     PL   + S+AS G + PL  
Sbjct: 4008 SVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLP- 4066

Query: 865  APDSRVTSTSQMMP--------TASGDMCTLPVRA--PASGGVSSPLVRAPASGT----- 909
              D+   ST    P         ++G    LPV +    S G ++PL  + A+       
Sbjct: 4067 VTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSS 4126

Query: 910  ----------MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPAS 959
                      M+TP  +       +T     ++   +ST  +TAM +   + P+   P  
Sbjct: 4127 DSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPER 4186

Query: 960  GTMPMP 965
            G    P
Sbjct: 4187 GVSLFP 4192



 Score =  103 bits (257), Expect = 1e-21
 Identities = 274/1244 (22%), Positives = 446/1244 (35%), Gaps = 221/1244 (17%)

Query: 38   DVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPP-LMPASD 96
            D+     + Q     T++     T TQ+MTS +F + S     V N    +PP  M  S 
Sbjct: 69   DISASSQNHQTKSTETTSKAQTDTLTQMMTSTLFSSPS-----VHNVMETAPPDEMTTSF 123

Query: 97   SGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLM 156
              +++  LM  S +     + M      TL     TS  G  S    + P    +S T  
Sbjct: 124  PSSVTNTLMMTSKT-----ITMTTSTDSTLGNTEETSTAGTES----STPVTSAVSITAG 174

Query: 157  VAPDSAEIS---PLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNP 213
                S   S    +   + SS    T    T+     ST       +   SP +      
Sbjct: 175  QEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHN--VT 232

Query: 214  GVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALAS------GEISSLLMSGTDSEA 267
            G +S +  P+  +   S   +T+       K+ +T          GE SS+ ++G+    
Sbjct: 233  GTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGS-LMP 291

Query: 268  ISSLIMSAVASGGTSP---QPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL 324
            ++S  +      G SP     TSTQ++                      S   +  S   
Sbjct: 292  VTSAALVTFDPEGQSPATFSRTSTQDTTAF-------------------SKNHQTQSVET 332

Query: 325  LSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV---- 380
              V     ++TL          SP+     PSG +  +T P+  +   SP S  N     
Sbjct: 333  TRVSQINTLNTLTPVTTSTVLSSPSGFN--PSGTVSQETFPSGETTTSSPSSVSNTFLVT 390

Query: 381  ----------DSEMMSNPPVRATASGVMSAPPVRALD---SGAMSTPLMGAPASGNMSTL 427
                      DS + +      + SG +SA   +      S  +ST L  +     +ST 
Sbjct: 391  SKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTA 450

Query: 428  QKTVPASGAMTT---------------------SLMTVPSS------GVMSTEQMSATAS 460
              T  + GA TT                        T PSS         S  ++ +T++
Sbjct: 451  FHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTST 510

Query: 461  RVMSAQLT---MAKTSGAMPTGSMKAVA-KQYKRATASGKMSTPLRRAPTSGAMS--TQP 514
               +  +T      T+G +P    K  A  +    T     ST L +   +GA +  TQ 
Sbjct: 511  GAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQE 570

Query: 515  VTATASETMSMPQLTV------PASGSMSMLQMRAPVSEAMSMPQMR--TMASGLTSAAQ 566
               T    +S P  +V        S S S +  R    +  + P     T+ S  TS  +
Sbjct: 571  TGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQE 630

Query: 567  MKAMTS-GAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLM------ 619
              A++  G    P  T ++  + S   M DT +  ++ P     ASG     ++      
Sbjct: 631  SPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKT--VTTPGSSFTASGHSPSEIVPQDAPT 688

Query: 620  -------TPKASGTMFTEKMTTTASEAMP------------TLLMRDTVSGALSMPQMTD 660
                    P  +G   T +  TTA +A P            T L +   +GAL++     
Sbjct: 689  ISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSK---TGALTLANSVV 745

Query: 661  TASGG-------LSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAK 713
            +  GG        SAS   DTA+    T Q  +T + G +    +  +P    +    A 
Sbjct: 746  STPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQT----QTSEPASSGSRTTSAG 801

Query: 714  VSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSE----TMST 769
             +    S    T   G   +S     T      +  +    ST  + + ++      +ST
Sbjct: 802  TATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVST 861

Query: 770  PLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASG 829
             +  +  PG     L+ AS++G    P  ++  +   A+P  + A   M+  Q T T+ G
Sbjct: 862  GMASSIVPGTFHPTLSEASTAGR---PTGQSSPTSPSASPQETAAISRMAQTQRTRTSRG 918

Query: 830  MMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCT--- 886
              +     +A  + +   P   S  S G++ P         T T  + P+ SG   T   
Sbjct: 919  SDTISLASQATDTFSTVPPTPPSITSTGLTSP--------QTETHTLSPSGSGKTFTTAL 970

Query: 887  ------LPV--RAPASGGVSSPLVRAPASGTMS-----TPLRRPSACETVSTELMRASAS 933
                  LPV   + AS G ++PL    AS   +      P+  PS+  T  T  +  + +
Sbjct: 971  ISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDT 1030

Query: 934  GHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPL--MSAMASGEMSMPLMETMASGA---- 987
               ST   T +     S     A    + P+P+   S+ ++G ++ PL  T  S A    
Sbjct: 1031 SSESTGHVTPLPVTSFSS----ASTGDSTPLPVTDTSSASTGHVT-PLPVTSLSSASTGD 1085

Query: 988  ------TSTLQTSVANSRSMSLSQTTYTVSGRMATAPI--RASASGARSTSFM---RASV 1036
                  T T   S  ++ S+ ++ T+   +G     P+   +SAS   +TS      +SV
Sbjct: 1086 TTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSV 1145

Query: 1037 SGSMPMPLPRATASGCGMGMSMP---QMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMS 1093
            S     PL    AS    G + P      ++ S G +TPL        +++P +A    +
Sbjct: 1146 STGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPL-------PVTSPSSASTGHA 1198

Query: 1094 TPEIKATDSGEASTSH---INITASGSKPTSHMTA---TTPETA 1131
            TP +  TD+  AST H   + +T + S  T H T+   T P  A
Sbjct: 1199 TP-LLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAA 1241



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 219/995 (22%), Positives = 356/995 (35%), Gaps = 156/995 (15%)

Query: 235  TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGI 294
            T EDT          + S   ++  + G  + A S      +++   + Q  ST+ +   
Sbjct: 29   TTEDTLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKA 88

Query: 295  PTPLMSDLDSGIMSSLLMSSPG-SEVMSTPLLSVPDAGEMST-LPKPAPDAEAMSP---A 349
             T  ++ +    M+S L SSP    VM T   + PD  EM+T  P    +   M+     
Sbjct: 89   QTDTLTQM----MTSTLFSSPSVHNVMET---APPD--EMTTSFPSSVTNTLMMTSKTIT 139

Query: 350  LMTALPSGVMPTQTMPAPGSGAMSP-------------------WSTQNVDSEMMS-NPP 389
            + T+  S +  T+     G+ + +P                   W T   D+   S N  
Sbjct: 140  MTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHW 199

Query: 390  VRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTL-QKTVPASGAMTTSLMTVPSSG 448
             R+T +   S      L     STP           T+ QKT P+    T+SL +V ++ 
Sbjct: 200  TRSTQTTRESQ--TSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTS 257

Query: 449  VMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP-TS 507
            +M++E+++ T S   S      +TS    TGS+  V       +A+     P  ++P T 
Sbjct: 258  MMTSEKITVTTS-TGSTLGNPGETSSVPVTGSLMPVT------SAALVTFDPEGQSPATF 310

Query: 508  GAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPV--SEAMSMPQMRTMASGLTSAA 565
               STQ  TA +    +    T   S  ++ L    PV  S  +S P      SG   + 
Sbjct: 311  SRTSTQDTTAFSKNHQTQSVETTRVS-QINTLNTLTPVTTSTVLSSP------SGFNPSG 363

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
             +   T  +  T   T+  S  ++T L+    S V   P  R    G   +  ++   + 
Sbjct: 364  TVSQETFPSGETT--TSSPSSVSNTFLV---TSKVFRMPTSRDSTLGNTEETSLSVSGTI 418

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM- 684
            +  T K++T        +   DT+S ALS   +       +S +     + GA +T +  
Sbjct: 419  SAITSKVST--------IWWSDTLSTALSPSSLPPK----ISTAFHTQQSEGAETTGRPH 466

Query: 685  -TATVSGGMSMPLMRAQDPGVMPASLMR---------------AKVSGKMLSQPMSTQDP 728
              ++ S G+S  +    +    P+S                     + ++++   ST   
Sbjct: 467  ERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTA 526

Query: 729  GGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV---------RAWTSETMSTPLMRTSDPGE 779
            G +   P K    G  +   PT+    + T+           WT ET +T     S P  
Sbjct: 527  GTIPRVPSKVSAIG--EPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSY 584

Query: 780  RPSLLTRASSSGEMSLPLMRAPASGEIAT---------------PLRSPAY---GAMSAP 821
              + + + ++S   S P++    S +I T               P  SPA    G   AP
Sbjct: 585  SVTQMIKTATSPSSS-PMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAP 643

Query: 822  QMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMR--APDSRVTSTSQMMPT 879
            Q T  +    S  P         ++ P +  TASG     ++   AP     +T    PT
Sbjct: 644  QTTQESQTTRSVSPMTDTK---TVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPT 700

Query: 880  ASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTA 939
              G     P  A  +   S      P+ GT                     S +G ++ A
Sbjct: 701  GDGHTTQAPTTALQAAPSSHDATLGPSGGTS-------------------LSKTGALTLA 741

Query: 940  QTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSR 999
             +     GG       A AS T P       A+   +     T ASG T T + + + SR
Sbjct: 742  NSVVSTPGGPEGQWTSASAS-TSP----DTAAAMTHTHQAESTEASGQTQTSEPASSGSR 796

Query: 1000 SMSLSQTTYTVSGRMATAP-----IRASASGAR-STSFMRASVSGSMPMPLPRATASGCG 1053
            + S    T + SG   T P     I  S    R S++  R S +      L  A+AS   
Sbjct: 797  TTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGA 856

Query: 1054 MGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINIT 1113
            + +S    ++         L  AS  G  +   +     ++P+  A  S  A T     T
Sbjct: 857  IPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTR-T 915

Query: 1114 ASGSKPTSHMTATTP--ETAKPPPKEVPSFGMLTP 1146
            + GS   S  +  T    T  P P  + S G+ +P
Sbjct: 916  SRGSDTISLASQATDTFSTVPPTPPSITSTGLTSP 950


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  110 bits (276), Expect = 7e-24
 Identities = 269/1145 (23%), Positives = 411/1145 (35%), Gaps = 122/1145 (10%)

Query: 56   SDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSP 115
            S P  T++ L+  P     S      P S A +     ++ SG         S   A   
Sbjct: 1952 SSPPSTTSALVEEPTSYHSS------PGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 2005

Query: 116  LLMPA-------LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLA 168
            +++PA       L   T SP+ S S      PG  T P     S T   +P S   +   
Sbjct: 2006 IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP 2065

Query: 169  MPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDS----GELSPILMQDMNPGVMSTQPVPA- 223
                SSGV  +   +TS S   ST     PDS    G          +PG   T  +PA 
Sbjct: 2066 ASTTSSGV--SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2123

Query: 224  -----PSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVAS 278
                 PS E+ +          A+S    TAL+ G+ S+   S   S   ++L   +  S
Sbjct: 2124 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS-THTTLFPDSTTS 2182

Query: 279  GGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPK 338
             G     T   +S G P   +S   S        +SPG +  ST   + P     ST   
Sbjct: 2183 SGIVEASTRVHSSTGSPRTTLSPASS--------TSPGLQGESTAFQTHP----ASTHTT 2230

Query: 339  PAPDAEAMSPALMTAL---PSGVMPTQTMPA----PGSGAMSPWSTQNVDSEMMSNPPVR 391
            P+P + A +P   +       G  PT   PA     G    S     + D+   +     
Sbjct: 2231 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 2290

Query: 392  ATASGVMSAPPVRALDSGAMSTPLMGA---PASGNMSTLQKTVPASGAMTTSLMTVPSSG 448
            +T SG   +   R        T L G+   P     ST   + P S   T S  ++ S G
Sbjct: 2291 STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2350

Query: 449  VMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSG 508
            V   E+ + + S+  S   T++  S   P G  +     Y  +  S + +T   R PT+ 
Sbjct: 2351 V--GEESTTSRSQPGSTHSTVSPASTTTP-GLSEESTTVYSSSPGSTE-TTVFPRTPTTS 2406

Query: 509  AMSTQPVT-----ATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTS 563
                +P T     A+   T+     T       S     +P S    +P   T A  L  
Sbjct: 2407 VRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-LGE 2465

Query: 564  AAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKA 623
             +     +SG+  T L  A++  +TS L+   T S +       +   G+ + P ++ K 
Sbjct: 2466 ESTTFPSSSGSTGTTLSPARS--TTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK- 2522

Query: 624  SGTMFTEKMTTTASEAMPTLL---MRDTVSGALSMPQMT-------DTASGGLSA-SLMR 672
            S T +T   +  A+ +  T     + +  S + S P  T        T + GLS  S   
Sbjct: 2523 STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS 2582

Query: 673  DTASGAMSTSQMTA--TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMST--QDP 728
             ++ G+  T+ + A  T SG           PG    +L     +     Q  +T    P
Sbjct: 2583 HSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSP 2642

Query: 729  GGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRAS 788
            G    +     T     + + T    ST + R   S   ST        GE  +  T  +
Sbjct: 2643 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST---SPGLQGESTTFQTHPA 2699

Query: 789  SSGEMSLPLMRAPASGEIATPL-RSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSM 847
            S+     P   A A  E +T   RSP     +    ++T SG         +    + + 
Sbjct: 2700 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 2759

Query: 848  PLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSP----LVR 903
            P +  + + G       +  SR++  S  + T  G   T  +   ++   SSP       
Sbjct: 2760 PSSAHSTTSGRG----ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 2815

Query: 904  APASGTM-----STPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPA 958
            +PAS T       +   R     T ST    ++ +  +S   TT   S   S      P 
Sbjct: 2816 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR 2875

Query: 959  S------GTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSG 1012
            S      G  P    S  AS   ++   ++  SG T   + S A   S + +QT     G
Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT---EESTAFPGSPASTQT-----G 2927

Query: 1013 RMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTP 1072
              AT  +  +  G  ST+F  +S S    +   R+T SG  +G S P   +  S   +T 
Sbjct: 2928 LPAT--LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL-VGESTPSRLSPSSTETTTL 2984

Query: 1073 LMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASG---SKPTSH-MTATTP 1128
                  PG+ +TP  +    ST    +  S +A+ S    T+SG      TSH    +T 
Sbjct: 2985 ------PGSPTTP--SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 3036

Query: 1129 ETAKP 1133
             TA P
Sbjct: 3037 TTAFP 3041



 Score =  110 bits (274), Expect = 1e-23
 Identities = 258/1141 (22%), Positives = 413/1141 (36%), Gaps = 151/1141 (13%)

Query: 95   SDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSAT 154
            S   A++  ++PA  + ++       +   T SP+ S S      PG  T P     S T
Sbjct: 585  SSPDAMATTVLPAGSTPSV------LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 638

Query: 155  LMVAPDSAEISPLAMPAPSSGV----------------------VCTPIMSTSSSEAMST 192
               +P S + + L     SSGV                         P +S  S+ + S+
Sbjct: 639  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 698

Query: 193  PLMLAPDSGELSP--ILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTAL 250
            P    P    LSP       + P   +    P  +   + P   T       S  + ++ 
Sbjct: 699  P---GPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 755

Query: 251  ASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNS------------GGIPTPL 298
             S   +      T  +  S+   S  +S  T P P +T ++              IPT  
Sbjct: 756  RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTH 815

Query: 299  MS--DLDSGIM--SSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTAL 354
            +S     SG++  S+   SSPG    ST  +  P++   S   + +  + + +   +++ 
Sbjct: 816  ISARSTTSGLVEESTTYHSSPG----STQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 871

Query: 355  PSGVM-----PTQTMPAPGSGAMSPWSTQNVDSEMMSNP---------------PVRATA 394
            PS        PT    +PGS A + +   +  S                     P R+T 
Sbjct: 872  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 931

Query: 395  SGVMSAPPVRALDSGAMSTPLM----GAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
            S ++       + SG+M T  +      P     ST   + P S A T S  +  SSGV 
Sbjct: 932  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV- 990

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAM 510
             +E+ + + SR  S   T    S   P  S  +        ++ G   T L  A T+ + 
Sbjct: 991  -SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH----SSPGSTDTTLLPASTTTSG 1045

Query: 511  STQPVTATASETMSMPQLTVPAS------GSMSMLQMRAPVSEAMSMPQMRTMASGLTSA 564
             +Q  T + S + S      P S      G  S      P S   ++    T +SG+  A
Sbjct: 1046 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 1105

Query: 565  AQMKAMTSGAMSTPLMTAQTSG----STSTLLMRDTASGVMSCPQMRSLASGALSKPLMT 620
            +     ++G+  T L  A ++       ST      AS   + P   S A+  + +    
Sbjct: 1106 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS-THTTPSPPSTATAPVEESTTY 1164

Query: 621  PKASG----TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTAS 676
             ++ G    T F    TT+      T+      +   +      T SG   ++  R +  
Sbjct: 1165 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 1224

Query: 677  GAMSTSQMTATVSGGMS------MPLMRAQDPGVMPASLMRAKV---SGKMLSQPMSTQD 727
                T+   +T + G+S          R+    + PAS+    V   S    SQP ST  
Sbjct: 1225 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 1284

Query: 728  PGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRA 787
                ++SP  + T G   ++  ++ V S+   R  T  T+      TS  GE P+     
Sbjct: 1285 ----TVSPASTTTPG---LSEESTTVYSSS--RGSTETTVFPHSTTTSVHGEEPTTFHSR 1335

Query: 788  SSSGEMSLPLMRAPASG---EIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGA 844
             +S   +L    +  SG   E      SPA      P    TA     S     +  S  
Sbjct: 1336 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 1395

Query: 845  MSMPLTRSTASG--GMSMPLMRAPDSRVTSTSQMMPT--ASGDMCTLPVRAPASGGVSSP 900
              +   RST SG  G S P   +P S  T+T    PT  +  +  T    +P S   +  
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 1455

Query: 901  LVRAPASGT---MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAP 957
                 +SG     ST   +P +  T  T    ++ +  +S   TT+  S G ++  + +P
Sbjct: 1456 PATTTSSGVSEESSTSHSQPGSTHT--TAFPDSTTTSDLSQEPTTSHSSQGSTEATL-SP 1512

Query: 958  ASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATA 1017
             S T       A + G+ S     +     T+ L      S  +  S  T++ +G + T 
Sbjct: 1513 GSTT-------ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 1565

Query: 1018 PIRASASGA----RSTSFMR-ASVSGSMPMPLPRATASGCGMGM---SMPQMT-ATDSRG 1068
               AS++ A     ST+F    S S + P P P  TA+   +     S P  T  T    
Sbjct: 1566 LTPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAPVEVSTTYHSRPSSTPTTHFSA 1624

Query: 1069 MSTPLMRASGPGTMSTPQTAFGVMSTPEIKATD--SGEASTSHINITASGSKPTSHMTAT 1126
             ST L R+    T+ +   A G    P   AT    GE +TS I   +SGS  T+ +  +
Sbjct: 1625 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSGSTETTALPGS 1681

Query: 1127 T 1127
            T
Sbjct: 1682 T 1682



 Score =  106 bits (265), Expect = 1e-22
 Identities = 278/1212 (22%), Positives = 434/1212 (35%), Gaps = 199/1212 (16%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAP-----LMGVPNS-----GALSPPLMPASD--SGA 99
            S + S  G  ST   +S      SAP     L+  P S     G+ +    P S   SG 
Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 3546

Query: 100  LSPLLMPASDSGALSPLLMPA-------LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMS 152
                    S   A   +++PA       L   T SP+ S S      PG  T P     S
Sbjct: 3547 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 3606

Query: 153  ATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDS----GELSPILM 208
             T   +P S   +       SSGV  +   +TS S   ST     PDS    G       
Sbjct: 3607 TTFHSSPRSPATTLSPASTTSSGV--SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 3664

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
               +PG   T  +PA ++ + S  + T   + + S    TAL+ G  ++L          
Sbjct: 3665 SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTD--TALSPGSTTALSFGQE----- 3717

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            S+   S+  S  T+  P ST +SG +             S+ + SS GS     P  ++ 
Sbjct: 3718 STTFHSSPGSTHTTLFPDSTTSSGIVEA-----------STRVHSSTGS-----PRTTLS 3761

Query: 329  DAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWST-----QNVDSE 383
             A   S      P  +  S A  T   S    T T P+P S A +P        ++  S 
Sbjct: 3762 PASSTS------PGLQGESTAFQTHPAS----THTTPSPPSTATAPVEESTTYHRSPGST 3811

Query: 384  MMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP-ASGNM-STLQKTVPASGAMTTSL 441
              ++ P  +T SG               ST    +P ASG   S+   T    G  TTS 
Sbjct: 3812 PTTHFPASSTTSG-----------HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860

Query: 442  MTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVA---------KQYKRAT 492
            ++ P S  ++T   S T   +  A  T   +S   PT ++   +             R+ 
Sbjct: 3861 IS-PGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 3918

Query: 493  ASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMR------APVS 546
                 ST    + T+  +S +  T  +S   S      P S + S+ +         P S
Sbjct: 3919 PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPAS 3978

Query: 547  EAMSMPQMRTMASGLTSAAQ----MKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               ++    +  SGLT  +       A T   +   L TA     ++T      ++G   
Sbjct: 3979 THTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL 4038

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTV------SGALSMP 656
             P  RS  SG + +   TP       TE  T   S   P+L  + T       S   ++ 
Sbjct: 4039 SP-ARSTTSGLVGE--STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 4095

Query: 657  QMTDTASGGLSASLMRDTASGAMSTSQM--TATVSGGMSMPLMRAQDPGVMPASLMRAKV 714
              T T+SG    S    +  G+  T+    + T SG    P       G   A+L     
Sbjct: 4096 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155

Query: 715  SGKMLSQPMST--QDPGG--MSMSPMKSMTAGGMQMNSPTSD------VMSTP------- 757
            +   L Q  +T    PG    ++ P  ++T+G ++ ++PT           TP       
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTG 4215

Query: 758  ------TVRAWTSETMSTPLMRT-------------SDPGERPSLLTRASSS----GEMS 794
                  T ++W S + +TP   +             S P   P+    ASS+     E S
Sbjct: 4216 LQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 4275

Query: 795  LPLMRAP-ASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAM-------- 845
              +  +P A+G    P RS     +  P  +  +SG   +     +  +  +        
Sbjct: 4276 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 4335

Query: 846  SMPLTRSTASGGMSMPLMRAPDSRVTSTSQ---MMPTASGDMCTLP-VRAPASGGVSSP- 900
            S P +  T     S       +   TS S+   M  TA     T+P V   ++   SSP 
Sbjct: 4336 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPG 4395

Query: 901  ---LVRAPASGTMS-------TPLRRPSACE-------TVSTELMRASASGHMSTA--QT 941
                  +P S T S       T    P + E       T ++ L+ AS   H ST    T
Sbjct: 4396 STDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHT 4455

Query: 942  TAMVSG-----GMSKPLMRAPAS-GTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSV 995
            T   +G     G S      P S  T P P  +  A  E+S     T + G+ S+  T+ 
Sbjct: 4456 TLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS-----TTSHGSPSSTPTTH 4510

Query: 996  ANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMG 1055
             ++ S +L ++  + +   +      + S ARST+      SG +       ++ G    
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTT------SGLVEESTTYHSSPGSTQT 4564

Query: 1056 MSMPQMTATDSRGMSTPLMRASGPGTMST-PQTAFGVMSTPEIKATDSGEASTSHINITA 1114
            M  P+   T  RG  +    +S   T+S+ P T   ++  P    +  G  +T+H   ++
Sbjct: 4565 MHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 4624

Query: 1115 SGSKPTSHMTAT 1126
            + S  +   TA+
Sbjct: 4625 TTSGRSEESTAS 4636



 Score =  105 bits (263), Expect = 2e-22
 Identities = 280/1225 (22%), Positives = 432/1225 (35%), Gaps = 225/1225 (18%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAP-----LMGVPNS-----GALSPPLMPASD--SGA 99
            S + S  G  ST   +S      SAP     L+  P S     G+ +    P S   SG 
Sbjct: 847  SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 906

Query: 100  LSPLLMPASDSGALSPLLMPA-------LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMS 152
                    S   A   +++PA       L   T SP+ S S      PG  T P     S
Sbjct: 907  SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS 966

Query: 153  ATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDS----GELSPILM 208
             T   +P S   +       SSGV  +   +TS S   ST     PDS    G       
Sbjct: 967  TTFHSSPRSPATTLSPASTTSSGV--SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 1024

Query: 209  QDMNPGVMSTQPVPA------PSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSG 262
               +PG   T  +PA      PS E+ +    +     A+S    TAL+ G+ S+   S 
Sbjct: 1025 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSN 1084

Query: 263  TDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMST 322
              S   ++L   +  S G     T   +S G P   +S   S        +SPG +  ST
Sbjct: 1085 PGSTH-TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS--------TSPGLQGEST 1135

Query: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWST----- 377
               + P +                              T T P+P S A +P        
Sbjct: 1136 AFQTHPAS------------------------------THTTPSPPSTATAPVEESTTYH 1165

Query: 378  QNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP-ASGNM-STLQKTVPASG 435
            ++  S   ++ P  +T SG               ST    +P ASG   S+   T    G
Sbjct: 1166 RSPGSTPTTHFPASSTTSG-----------HSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214

Query: 436  AMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASG 495
              TTS ++ P S  ++T   S T   +  A  T   +S   PT ++   +     +   G
Sbjct: 1215 ESTTSRIS-PGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSPAS---MTSLGVG 1269

Query: 496  KMSTPLRRAPTSGAMSTQPVTAT-----------------ASETMSMP-QLTVPASGSMS 537
            + ST  R  P S   +  P + T                 ++ET   P   T    G   
Sbjct: 1270 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329

Query: 538  MLQMRAPVSEAMSMPQMRTMASGLTSAAQ----MKAMTSGAMSTPLMTAQTSGSTSTLLM 593
                  P S   ++    +  SGLT  +       A T   +   L TA     ++T   
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389

Query: 594  RDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTV---- 649
               ++G    P  RS  SG + +   TP       TE  T   S   P+L  + T     
Sbjct: 1390 SSGSTGTKLSP-ARSTTSGLVGE--STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 1446

Query: 650  --SGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM--TATVSGGMSMPLMRAQDPGVM 705
              S   ++   T T+SG    S    +  G+  T+    + T S     P       G  
Sbjct: 1447 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST 1506

Query: 706  PASLMRAKVSGKMLSQPMST--QDPGG--MSMSPMKSMTAGGMQMNSPTSD------VMS 755
             A+L     +   L Q  +T    PG    ++ P  ++T+G ++ ++PT           
Sbjct: 1507 EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1566

Query: 756  TP-------------TVRAWTSETMSTPLMRTSDPG--ERPSLLTRASSSGEMSLPLMRA 800
            TP             T ++W S + +TP    S PG    P  ++    S   S P    
Sbjct: 1567 TPASSTSAGLQEESTTFQSWPSSSDTTP----SPPGTTAAPVEVSTTYHSRPSSTPTTHF 1622

Query: 801  PAS------GEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAM-SMPLTRST 853
             AS       E +T + S      +A   T +A+ ++   P      SG+  +  L  ST
Sbjct: 1623 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 1682

Query: 854  ASGGMS------MPLMRAPD-------------SRVTSTSQMMP-----TASGDMCTLP- 888
             + G+S          R+PD             S  ++TS   P     TA     T+P 
Sbjct: 1683 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1742

Query: 889  VRAPASGGVSSP----LVRAPASGTMS-------TPLRRPSACE-------TVSTELMRA 930
            V   ++   SSP       +P S T S       T    P + E       T ++ L+ A
Sbjct: 1743 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1802

Query: 931  SASGHMSTA--QTTAMVSG-----GMSKPLMRAPAS-GTMPMPLMSAMASGEMSMPLMET 982
            S   H ST    TT   +G     G S      P+S  TMP P  +  A  E+S     T
Sbjct: 1803 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS-----T 1857

Query: 983  MASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPM 1042
             + G+ S+  T+  ++ S +L ++  + +   +      + S ARST+      SG +  
Sbjct: 1858 TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT------SGLVEE 1911

Query: 1043 PLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMST-PQTAFGVMSTPEIKATD 1101
                 ++ G    M  P+ +    R   +    +S   T+S+ P T   ++  P    + 
Sbjct: 1912 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1971

Query: 1102 SGEASTSHINITASGSKPTSHMTAT 1126
             G  +T+H   +++ S  +   TA+
Sbjct: 1972 PGSTATTHFPDSSTTSGRSEESTAS 1996



 Score =  101 bits (252), Expect = 4e-21
 Identities = 275/1222 (22%), Positives = 423/1222 (34%), Gaps = 206/1222 (16%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSG 111
            +TS S PG T T        D+ + P +   ++ + S P       G+    L+PAS + 
Sbjct: 2078 TTSHSRPGSTHTTAFP----DSTTTPGLSRHSTTSHSSP-------GSTDTTLLPASTTT 2126

Query: 112  ALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPA 171
            +      P+ +S T S     S    +SPG  T   FG  S T   +P S   +      
Sbjct: 2127 S-----GPSQES-TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2180

Query: 172  PSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQD---MNPGVMSTQPVPAPSSEA 228
             SSG+V     ST    +  +P      +   SP L  +         ST   P+P S A
Sbjct: 2181 TSSGIV---EASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237

Query: 229  MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTST 288
             +P+   +E T        T       SS     ++    S++  S+  + GT+P    +
Sbjct: 2238 TAPV---EESTTYHRSPGSTPTTHFPASSTTSGHSEK---STIFHSSPDASGTTPSSAHS 2291

Query: 289  QNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTP-LLSVPDAGEMST--LPKPAPDAEA 345
              SG            G  ++  +S   +E+ + P   + P   E ST     P      
Sbjct: 2292 TTSG-----------RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 2340

Query: 346  MSPALMTALPSGVMPTQTMPAPGS--GAMSPWSTQ----NVDSEMMSNPPVRATASGVMS 399
            +SPA MT+L  G   T +   PGS    +SP ST     + +S  + +    +T + V  
Sbjct: 2341 LSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 2400

Query: 400  APPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATA 459
              P  ++  G   T     PAS + +   +    SG +T      P S   +   + AT 
Sbjct: 2401 RTPTTSV-RGEEPTTFHSRPASTHTTLFTEDSTTSG-LTEESTAFPGSPASTQTGLPATL 2458

Query: 460  SRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKM--STPLRRAPTSGAMST----- 512
            +     + +    S +  TG+  + A    R+T SG +  STP R +P+S   +T     
Sbjct: 2459 TTADLGEESTTFPSSSGSTGTTLSPA----RSTTSGLVGESTPSRLSPSSTETTTLPGSP 2514

Query: 513  -----------------------QPVTATAS----------------ETMSMP-QLTVPA 532
                                    P T T+S                 T + P   T P 
Sbjct: 2515 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPG 2574

Query: 533  SGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTS------- 585
                S     +P S   ++    T  SG +  +     + G+  T L    T+       
Sbjct: 2575 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE 2634

Query: 586  --------GSTSTLLMRD--TASGVMSCPQMRSLASGA----LSKPLMT----------- 620
                    GST T L  D  T+SG++        ++G+    LS    T           
Sbjct: 2635 STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTF 2694

Query: 621  ---PKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASG 677
               P ++ T  +   T TA     T   R   S   +    + T SG    S +  ++  
Sbjct: 2695 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 2754

Query: 678  AMSTSQMTA-TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQ-----------PMST 725
            A  T+  +A + + G          PG    + +    +   LS+           P +T
Sbjct: 2755 ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 2814

Query: 726  QDPGGM-SMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLL 784
              P  M S+   +  T    Q  S  S V    T     SE  +T  + +S PG   + +
Sbjct: 2815 LSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT--VYSSSPGSTETTV 2872

Query: 785  ----TRASSSGEMSLPLMRAPAS----------------GEIATPLRSPAYGAMSAPQMT 824
                T  S  GE        PAS                 E      SPA      P   
Sbjct: 2873 FPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 2932

Query: 825  ATASGMMSSMPQVKAPISGAMSMPLTRSTASG--GMSMPLMRAPDSRVTSTSQMMPTASG 882
             TA     S     +  S   ++   RST SG  G S P   +P S  T+T    PT   
Sbjct: 2933 TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT--- 2989

Query: 883  DMCTLPVRAPASGGVSSPLVRAPAS--GTMSTPLRRPSACETVSTELMRASASGHMSTAQ 940
                     P+    S+    +P S   T+S      S     S+       S H +   
Sbjct: 2990 --------TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 3041

Query: 941  TTAMVSGGMSKPLMRAPASGTMPMPL----MSAMASGEMSMPLMETMASGATSTLQTSVA 996
             +   SG   +P     + G+    L     +A + G+ S     +     T+ L     
Sbjct: 3042 DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 3101

Query: 997  NSRSMSLSQTTYTVSGRMATAPIRASASGA----RSTSFMR-ASVSGSMPMPLPRATASG 1051
             S  +  S  T++ +G + T    AS++ A     ST+F    S S + P P P  TA+ 
Sbjct: 3102 TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAP 3160

Query: 1052 CGMGM---SMPQMT-ATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATD--SGEA 1105
              +     S P  T  T     ST L R+    T+ +   A G    P   AT    GE 
Sbjct: 3161 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 3220

Query: 1106 STSHINITASGSKPTSHMTATT 1127
            +TS I   +SGS  T+ +  +T
Sbjct: 3221 TTSPI---SSGSTETTALPGST 3239



 Score =  101 bits (252), Expect = 4e-21
 Identities = 271/1194 (22%), Positives = 422/1194 (35%), Gaps = 156/1194 (13%)

Query: 60   GTSTQLMTSPVFDTMSAPLMGVPNSGALSPP-----LMPASDSGALSPLLMPAS------ 108
            G ST    SP   T +  L G P + +LS         P S    LSP    +S      
Sbjct: 2967 GESTPSRLSPS-STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 3025

Query: 109  -----DSGALSPLLMPALDSGTLS-----PLLSTSEYG----VMSPGMMTIPDFGTMSAT 154
                   G+      P  DS T S     P  S S  G     +SPG  T    G  S T
Sbjct: 3026 STSHSQPGSTHTTAFP--DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTT 3083

Query: 155  LMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPG 214
               +P   E + L     +SG+V     + SS+ ++ T L  A  +              
Sbjct: 3084 FHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 3143

Query: 215  VMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMS 274
              S+   P+P     +P++++   T   S+   T       SS  +  ++    S+ + S
Sbjct: 3144 PSSSDTTPSPPGTTAAPVEVS---TTYHSRPSSTPTTHFSASSTTLGRSEE---STTVHS 3197

Query: 275  AVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM----SSPGSEVMSTPLLSVPDA 330
            +  + GT+  PT +  S  +  P  S + SG   +  +    ++ G    ST   S P +
Sbjct: 3198 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 3257

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
             +  T   PA    +      T   S    T T   PGS  M   S ++  S   S+P  
Sbjct: 3258 PD--TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH--SSP-- 3311

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGV- 449
              +    +S     A   G  ST     P S   + L     ASG +  S     S+G  
Sbjct: 3312 -GSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 3370

Query: 450  --------MSTEQMSATASR--------------VMSAQLTMAKTSGAMPTGSMKAVAKQ 487
                     +T Q  +T  +                SA + ++ TS   P+ +       
Sbjct: 3371 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 3430

Query: 488  YKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSE 547
                    + ST +  +P + A +  P  +T S  +   + T   S   S   M  P S+
Sbjct: 3431 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE--ESTTYHSSPGSTQTMHFPESD 3488

Query: 548  AMS--MPQMRTMASGLT-SAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDT-------- 596
              S    +  T  S  T + +   + TS  +  P     + GST+T    D+        
Sbjct: 3489 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 3548

Query: 597  ----------ASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKM----TTTASEAMPT 642
                      A+G +  P  RS  S  L +   +P +SG+M T  +    TT       T
Sbjct: 3549 ESTASHSSQDATGTIVLP-ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 3607

Query: 643  LLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM-TATVSGGMSMPLMRA-Q 700
                   S A ++   + T+SG    S    +  G+  T+    +T + G+S     +  
Sbjct: 3608 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 3667

Query: 701  DPGVMPASLMRAKVSGKMLSQPMSTQDPGGMS----MSPMKSMTAGGMQMNSPT--SDVM 754
             PG    +L+ A  +    SQ  +T      S    +SP  S TA      S T  S   
Sbjct: 3668 SPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP-GSTTALSFGQESTTFHSSPG 3726

Query: 755  STPTVRAWTSETMSTPLMRT-----SDPGERPSLLTRASSS-----GEMSLPLMRAPASG 804
            ST T   +   T S+ ++       S  G   + L+ ASS+     GE S      PAS 
Sbjct: 3727 STHTT-LFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE-STAFQTHPAST 3784

Query: 805  EIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRST-------ASGG 857
               TP  SP   A +  + + T      S P    P S   S    +ST       ASG 
Sbjct: 3785 H-TTP--SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 3841

Query: 858  MSMPLMRAPDSRVTSTSQMMPTASGDMCTLP--VRAPASGGVSSPLVRAPASGTMS-TPL 914
                       R  ST+  +   S ++ TLP     P     S+    +P S T + +P 
Sbjct: 3842 TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPA 3901

Query: 915  RRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASG-----TMPMPLMSA 969
               S      +   R+      ST    +  + G+S+      +S      T   P  + 
Sbjct: 3902 SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTT 3961

Query: 970  MASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTY------TVSGRMATAPIRASA 1023
             +          +  +   +TL T  + +  ++   T +      T +G  AT  +  + 
Sbjct: 3962 TSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT--LTTAD 4019

Query: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMS 1083
             G  ST+F  +S S    +   R+T SG  +G S P   +  S   +T       PG+ +
Sbjct: 4020 LGEESTTFPSSSGSTGTKLSPARSTTSGL-VGESTPSRLSPSSTETTTL------PGSPT 4072

Query: 1084 TPQTAFGVMSTPEIKATDSGEASTSHINITASG---SKPTSH-MTATTPETAKP 1133
            TP  +    ST    +  S +A+ S    T+SG      TSH    +T  TA P
Sbjct: 4073 TP--SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 4124



 Score =  100 bits (250), Expect = 7e-21
 Identities = 267/1176 (22%), Positives = 420/1176 (35%), Gaps = 170/1176 (14%)

Query: 52   STSASDPGGTSTQLM----TSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPA 107
            +TS S PG T + +     T+P     S  +    + G+    + P S + ++       
Sbjct: 2830 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS-SSPGSTETTVFPRSTTTSVRGEEPTT 2888

Query: 108  SDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPL 167
              S   S       +  T S L   +E     PG       G + ATL  A    E +  
Sbjct: 2889 FHSRPASTHTTLFTEDSTTSGL---TEESTAFPGSPASTQTG-LPATLTTADLGEESTTF 2944

Query: 168  AMPAPSSGVVCTPIMSTSSS-EAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSS 226
               + S+G   +P  ST+S     STP  L+P S E + +      PG  +T  +   S+
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTL------PGSPTTPSLSEKST 2998

Query: 227  EAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPT 286
               +  +  D     +S    T+    E SS   S   S   ++   S   SG  S +PT
Sbjct: 2999 TFYTSPRSPDA---TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSG-LSQEPT 3054

Query: 287  STQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAM 346
            ++ +S G     +S        S   SS G +  ST   S P   E + LP     +  +
Sbjct: 3055 ASHSSQGSTEATLSP------GSTTASSLGQQ--STTFHSSPGDTETTLLPDDTITSGLV 3106

Query: 347  SPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRAL 406
              +  T   +G + T   PA  + A      Q   +   S P    ++S    +PP    
Sbjct: 3107 EASTPTHSSTGSLHTTLTPASSTSA----GLQEESTTFQSWP----SSSDTTPSPPGTTA 3158

Query: 407  DSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATA---SRVM 463
                +ST     P+S        T   S + TT   +  S+ V S+   + TA   +R  
Sbjct: 3159 APVEVSTTYHSRPSS------TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 3212

Query: 464  SAQLTMAKTSGAMPTGSMKAVAKQYKRATAS-GKMSTPLRRAPTSGAMSTQPVTATAS-- 520
            ++ L    T+  + +GS +  A      TA   + ST    +P S   +  P + T+S  
Sbjct: 3213 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 3272

Query: 521  -----ETMSMPQLT----VPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMT 571
                  + S P  T     P S +M  +   +  S +       T++ G T+A+ +   +
Sbjct: 3273 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 3332

Query: 572  SGAMSTPLMTAQTSGSTSTLLMRD--TASGVMSCPQMRSLASGALSKPLMTPKASGTMFT 629
            +   S P       GST T L+ D  TASG++        ++G+    L +P  S T   
Sbjct: 3333 TTFHSGP-------GSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL-SPAGSTTRQG 3384

Query: 630  EKMTTTA-SEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATV 688
            E  T  +   +  T     T + A      T   S   + +     +S  +  S+ + TV
Sbjct: 3385 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 3444

Query: 689  SGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG-MSMSPMKSMTAGGMQMN 747
                S P+  A  P   PA   R+  SG +         PG   +M   +S T  G    
Sbjct: 3445 H---SSPVATATTPS--PA---RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496

Query: 748  SPTSDVMSTPTVRA---WTSETMSTPLMRTSDPGER-----PSLLTRASSSGEMSLPLMR 799
            S TS   +T T+ +    TS  +  P    S PG       P   T +  S E +     
Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 3556

Query: 800  APASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTR-------- 851
              A+G I  P RS     +     +  +SG M +     +  +  +S   T         
Sbjct: 3557 QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSP 3616

Query: 852  -------STASGGMSMPLMRA------------PDSRVT------STSQMMPTASGDMCT 886
                   ST S G+S     +            PDS  T      ST+      S D   
Sbjct: 3617 ATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 3676

Query: 887  LPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQT----- 941
            LP     SG          +SG+  T L   S   T +    + S + H S   T     
Sbjct: 3677 LPASTTTSGSSQESTTSHSSSGSTDTAL---SPGSTTALSFGQESTTFHSSPGSTHTTLF 3733

Query: 942  -TAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRS 1000
              +  S G+ +   R  +S   P   +S  +S    +        G ++  QT  A++ +
Sbjct: 3734 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL-------QGESTAFQTHPASTHT 3786

Query: 1001 MSLSQTTYTVSGRMATAPIRASASGARS------TSFMRASVSG--SMPMPLPRATASGC 1052
                 +T       ATAP+  S +  RS      T F  +S +   S    +  ++    
Sbjct: 3787 TPSPPST-------ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839

Query: 1053 GMGMSMPQMTATDSRGMSTPLMRASG-------PGTMSTP---QTAFGVMSTPEIKATDS 1102
            G   S    T T  RG ST    + G       PG+ +TP   + +    S+P    T  
Sbjct: 3840 GTTPSSAHST-TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 3898

Query: 1103 GEASTSHINI----TASGSKP------TSHMTATTP 1128
              AS + + +    T S S+P       S  + TTP
Sbjct: 3899 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 3934



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 262/1183 (22%), Positives = 412/1183 (34%), Gaps = 180/1183 (15%)

Query: 54   SASDPGGTSTQLMTSPVFDTMSAP----LMGVPNSGALSPPLMPASDSGALSPLLMPASD 109
            S+SDP  T +    S  F T S      L    NSG      +  S  GA    L P+  
Sbjct: 184  SSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHS 243

Query: 110  SGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAM 169
            + ++       +     SP+ S S      PG  T       S T   +P S + +    
Sbjct: 244  ATSVF------VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPA 297

Query: 170  PAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAM 229
               SSGV  +   +TS S    T  +  PDS  +  +  +       ++  +P  +   +
Sbjct: 298  RTTSSGV--SEKSTTSHSRPGPTHTIAFPDSTTMPGVSQEST-----ASHSIPGSTDTTL 350

Query: 230  SPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI--SSLIMSAVASGGTSPQPTS 287
            SP   T       S    ++    + + L  + T S  +  S+ + S+  S  T+  P+S
Sbjct: 351  SPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSS 410

Query: 288  TQNSGGIPTPLMS--------DLDSGIMSSLLM------SSP---------------GSE 318
            +    G PT   S           SG  S+ +       SSP               G  
Sbjct: 411  STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHS 470

Query: 319  VMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQ 378
              STP+ S P A   +T P PA  A +      TA       TQTM  P S   S  S +
Sbjct: 471  EESTPVHSSPVA--TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE 528

Query: 379  NVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMT 438
            +      S    +++     +A    +  S   ST       S  +S   +   AS +  
Sbjct: 529  SATFHG-STTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP 587

Query: 439  TSLMT--VPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGK 496
             ++ T  +P+    S     +T S + S  +      G+     +   +  +  +  S  
Sbjct: 588  DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 647

Query: 497  MSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRT 556
             +T L  + TS  +S +  T+  S   S      P S +M  L   +  S +   P   T
Sbjct: 648  -TTHLPASMTSSGVSEESTTSH-SRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 705

Query: 557  MASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRD--TASGVMSCPQMRSLASGAL 614
            ++ G T+A+ +    +   S P       GST T L+ D  TASG++    M   +S   
Sbjct: 706  LSPGSTTASSLGPEYTTFHSRP-------GSTETTLLPDNTTASGLLEA-SMPVHSSTRS 757

Query: 615  SKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDT 674
                ++P  S T   E   +T   + P+   +DT       P    T S  +  S     
Sbjct: 758  PHTTLSPAGSTTRQGE---STTFHSWPS--SKDT------RPAPPTTTSAFVEPSTTSHG 806

Query: 675  ASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMS 734
            +  ++ T+ ++A           R+   G++  S           S P STQ     +M 
Sbjct: 807  SPSSIPTTHISA-----------RSTTSGLVEESTTYH-------SSPGSTQ-----TMH 843

Query: 735  PMKSMTAGGMQMNSPTSDVMSTPTVRA---WTSETMSTPLMRTSDPGER-----PSLLTR 786
              +S T  G    S TS   +T T+ +    TS  +  P    S PG       P   T 
Sbjct: 844  FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 903

Query: 787  ASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMS-------------- 832
            +  S E +       A+G I  P RS     +     +  +SG M               
Sbjct: 904  SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 963

Query: 833  --SMPQVKAPISGAMSMPLTRSTASG-------GMSMP----LMRAPDSRVT------ST 873
              S     +P S A ++    +T+SG         S P        PDS  T      ST
Sbjct: 964  ERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHST 1023

Query: 874  SQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSAC------------- 920
            +      S D   LP     SG          +SG+  T L   S               
Sbjct: 1024 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 1083

Query: 921  ---ETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMP--MPLMSAMASGEM 975
                T +T    ++ S  +  A T    S G  +  + +PAS T P      +A  +   
Sbjct: 1084 NPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL-SPASSTSPGLQGESTAFQTHPA 1142

Query: 976  SMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASG--ARSTSFMR 1033
            S     +  S AT+ ++ S    RS   + TT+         P  ++ SG   +ST F  
Sbjct: 1143 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF--------PASSTTSGHSEKSTIFHS 1194

Query: 1034 A-SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTM-------STP 1085
            +   SG+ P      T+   G G S     +  S  ++T     + PG         S+P
Sbjct: 1195 SPDASGTTPSSAHSTTS---GRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 1251

Query: 1086 QTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTP 1128
            ++    +S   + +   GE ST+  +   S     S  + TTP
Sbjct: 1252 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 1294



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 237/1094 (21%), Positives = 376/1094 (34%), Gaps = 176/1094 (16%)

Query: 60   GTSTQLMTSPVFDTMSAPLMGVPNSGALSPP-----LMPASDSGALSPLLMPAS------ 108
            G ST    SP   T +  L G P + +LS         P S    LSP    +S      
Sbjct: 4050 GESTPSRLSPS-STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108

Query: 109  -----DSGALSPLLMPALDSGTLS-----PLLSTSEYG----VMSPGMMTIPDFGTMSAT 154
                   G+      P  DS T S     P  S S  G     +SPG  T    G  S T
Sbjct: 4109 STSHSQPGSTHTTAFP--DSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166

Query: 155  LMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPG 214
               +P   E + L     +SG+V     + SS+ ++ T L  A  +              
Sbjct: 4167 FHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSW 4226

Query: 215  VMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMS 274
              S+   P+P S    P++++   T   S+   T       SS  +  ++    S+ + S
Sbjct: 4227 PSSSDTTPSPPSTTAVPVEVS---TTYHSRPSSTPTTHFSASSTTLGRSEE---STTVHS 4280

Query: 275  AVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM----SSPGSEVMSTPLLSVPDA 330
            +  + GT+  PT +  S  +  P  S + SG   +  +    ++ G    ST   S P +
Sbjct: 4281 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 4340

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPA----PGSGAMSPWSTQNVDSEMMS 386
             + +  P     +     +  +    G M T   P+    PG    S  S  +  S   +
Sbjct: 4341 PDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTT 4400

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
              P   TAS +           G  ST    +P S   + L     ASG +  S     S
Sbjct: 4401 LSPGSTTASSL-----------GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 4449

Query: 447  SGV---------MSTEQMSATASR--------------VMSAQLTMAKTSGAMPTGSMKA 483
            +G           +T Q  +T  +                SA + ++ TS   P+ +   
Sbjct: 4450 TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 4509

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRA 543
                        + ST +  +P + A +  P  +T S  +        + GS   +    
Sbjct: 4510 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 4569

Query: 544  PVSEAMSMPQMRTMASGLT-SAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDT------ 596
              + +    +  T  S  T + +   + TS  +  P     + GST+T    D+      
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 4629

Query: 597  ------------ASGVMSCPQMRSLASGALSKPLMTPKASGTMFT-------------EK 631
                        A+G +  P  RS  S  L +   +P +SG+M T             EK
Sbjct: 4630 SEESTASHSSQDATGTIVLPA-RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688

Query: 632  MTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGG 691
             TT  S                  P  T T     SAS      S  +  S+ + TV   
Sbjct: 4689 STTFHSS-----------------PSSTPTTH--FSAS------STTLGRSEESTTVH-- 4721

Query: 692  MSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG-MSMSPMKSMTAGGMQMNSPT 750
             S P+  A  P     S  R+  SG +         PG   +M   +S TA G    S T
Sbjct: 4722 -SSPVATATTP-----SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 4775

Query: 751  SDVMSTPTVR---AWTSETMSTPLMRTSDPG-----ERPSLLTRASSSGEMSLPLMRAPA 802
            S   +T T+    + TS  +  P    S PG       P   T +  S E +        
Sbjct: 4776 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDT 4835

Query: 803  SGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPL 862
            +G    P      G ++       + G M +     A   G  +      ++S       
Sbjct: 4836 NGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS------- 4888

Query: 863  MRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACET 922
             R+PD  ++  S    + SG+  +L  +A ++   + P      SG         S   +
Sbjct: 4889 -RSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFP-ASTTTSGLSQESTTFHSKPGS 4946

Query: 923  VSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMET 982
              T L   S +      + T   S   S     +PAS T+P   +S  ++   S P    
Sbjct: 4947 TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPG--LSEESTTFYSSP---- 5000

Query: 983  MASGATSTLQTSVANSRSMSLSQTT-----YTVSGRMATAPIRASASGARSTSFMRAS-V 1036
               G+T T   S +N+ S+   Q+T        +  +  A +  +  G  ST+F  +S  
Sbjct: 5001 ---GSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDA 5057

Query: 1037 SGSMPMPLPRATAS 1050
            +G+ P+P  R+TAS
Sbjct: 5058 TGTTPLP-ARSTAS 5070



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 137/594 (23%), Positives = 199/594 (33%), Gaps = 105/594 (17%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAP-----LMGVPNS-----GALSPPLMPASD--SGA 99
            S + S  G  ST   +S      SAP     L+  P S     G+ +    P S   SG 
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 4629

Query: 100  LSPLLMPASDSGALSPLLMPA-------LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMS 152
                    S   A   +++PA       L   T SP+ S S      PG  T P     S
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 4689

Query: 153  ATLMVAPD-------SAEISPLAMPAPSSGVVCTPI-MSTSSSEAMSTPLMLAPDSGELS 204
             T   +P        SA  + L     S+ V  +P+  +T+ S A ST       SG + 
Sbjct: 4690 TTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST------TSGLVE 4743

Query: 205  PILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLM---- 260
                   +PG  STQ +  P S   S    ++E   + S    T  +    +S L+    
Sbjct: 4744 ESTAYHSSPG--STQTMHFPESSTASGR--SEESRTSHSSTTHTISSPPSTTSALVEEPT 4799

Query: 261  ---SGTDSEAISSLIMSAVASG---------------GTSPQPTSTQNSGGIPTPLMSDL 302
               S   S A +    S+  SG               G +P P     SG I       +
Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 4859

Query: 303  DSGIMSSLLMS---SPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVM 359
              G M + L S   +PG    ST L S   + + +    PA    +      T+L S   
Sbjct: 4860 SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTL--SPASMTSSSISGEPTSLYSQAE 4917

Query: 360  PTQTMPAPGSGAMSPWSTQNV-------DSEMMSNPPVRATASGVMSAPPVRALDSGAMS 412
             T T   P S   S  S ++         +E   +P    T+S         +    A+S
Sbjct: 4918 STHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALS 4977

Query: 413  TPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKT 472
            T          +S    TVP     +T+  + P     STE  + + S  MS     +  
Sbjct: 4978 T----------VSPASTTVPGLSEESTTFYSSPG----STETTAFSHSNTMSIHSQQSTP 5023

Query: 473  SGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMP------ 526
                P G    V       T  G+ ST    +  +   +  P  +TAS+ +  P      
Sbjct: 5024 FPDSP-GFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYIS 5082

Query: 527  -----QLTVPASGSMSMLQMRAP--------VSEAMSMPQMRTMASGLTSAAQM 567
                     PAS S S L   +          S  +S   + T+A GL    Q+
Sbjct: 5083 PSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQI 5136


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score =  110 bits (274), Expect = 1e-23
 Identities = 258/1141 (22%), Positives = 413/1141 (36%), Gaps = 151/1141 (13%)

Query: 95   SDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSAT 154
            S   A++  ++PA  + ++       +   T SP+ S S      PG  T P     S T
Sbjct: 72   SSPDAMATTVLPAGSTPSV------LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 125

Query: 155  LMVAPDSAEISPLAMPAPSSGV----------------------VCTPIMSTSSSEAMST 192
               +P S + + L     SSGV                         P +S  S+ + S+
Sbjct: 126  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 185

Query: 193  PLMLAPDSGELSP--ILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTAL 250
            P    P    LSP       + P   +    P  +   + P   T       S  + ++ 
Sbjct: 186  P---GPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 242

Query: 251  ASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNS------------GGIPTPL 298
             S   +      T  +  S+   S  +S  T P P +T ++              IPT  
Sbjct: 243  RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTH 302

Query: 299  MS--DLDSGIM--SSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTAL 354
            +S     SG++  S+   SSPG    ST  +  P++   S   + +  + + +   +++ 
Sbjct: 303  ISARSTTSGLVEESTTYHSSPG----STQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 358

Query: 355  PSGVM-----PTQTMPAPGSGAMSPWSTQNVDSEMMSNP---------------PVRATA 394
            PS        PT    +PGS A + +   +  S                     P R+T 
Sbjct: 359  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 418

Query: 395  SGVMSAPPVRALDSGAMSTPLM----GAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
            S ++       + SG+M T  +      P     ST   + P S A T S  +  SSGV 
Sbjct: 419  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV- 477

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAM 510
             +E+ + + SR  S   T    S   P  S  +        ++ G   T L  A T+ + 
Sbjct: 478  -SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH----SSPGSTDTTLLPASTTTSG 532

Query: 511  STQPVTATASETMSMPQLTVPAS------GSMSMLQMRAPVSEAMSMPQMRTMASGLTSA 564
             +Q  T + S + S      P S      G  S      P S   ++    T +SG+  A
Sbjct: 533  PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 592

Query: 565  AQMKAMTSGAMSTPLMTAQTSG----STSTLLMRDTASGVMSCPQMRSLASGALSKPLMT 620
            +     ++G+  T L  A ++       ST      AS   + P   S A+  + +    
Sbjct: 593  STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS-THTTPSPPSTATAPVEESTTY 651

Query: 621  PKASG----TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTAS 676
             ++ G    T F    TT+      T+      +   +      T SG   ++  R +  
Sbjct: 652  HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 711

Query: 677  GAMSTSQMTATVSGGMS------MPLMRAQDPGVMPASLMRAKV---SGKMLSQPMSTQD 727
                T+   +T + G+S          R+    + PAS+    V   S    SQP ST  
Sbjct: 712  STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 771

Query: 728  PGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRA 787
                ++SP  + T G   ++  ++ V S+   R  T  T+      TS  GE P+     
Sbjct: 772  ----TVSPASTTTPG---LSEESTTVYSSS--RGSTETTVFPHSTTTSVHGEEPTTFHSR 822

Query: 788  SSSGEMSLPLMRAPASG---EIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGA 844
             +S   +L    +  SG   E      SPA      P    TA     S     +  S  
Sbjct: 823  PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 882

Query: 845  MSMPLTRSTASG--GMSMPLMRAPDSRVTSTSQMMPT--ASGDMCTLPVRAPASGGVSSP 900
              +   RST SG  G S P   +P S  T+T    PT  +  +  T    +P S   +  
Sbjct: 883  TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 942

Query: 901  LVRAPASGT---MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAP 957
                 +SG     ST   +P +  T  T    ++ +  +S   TT+  S G ++  + +P
Sbjct: 943  PATTTSSGVSEESSTSHSQPGSTHT--TAFPDSTTTSDLSQEPTTSHSSQGSTEATL-SP 999

Query: 958  ASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATA 1017
             S T       A + G+ S     +     T+ L      S  +  S  T++ +G + T 
Sbjct: 1000 GSTT-------ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 1052

Query: 1018 PIRASASGA----RSTSFMR-ASVSGSMPMPLPRATASGCGMGM---SMPQMT-ATDSRG 1068
               AS++ A     ST+F    S S + P P P  TA+   +     S P  T  T    
Sbjct: 1053 LTPASSTSAGLQEESTTFQSWPSSSDTTPSP-PGTTAAPVEVSTTYHSRPSSTPTTHFSA 1111

Query: 1069 MSTPLMRASGPGTMSTPQTAFGVMSTPEIKATD--SGEASTSHINITASGSKPTSHMTAT 1126
             ST L R+    T+ +   A G    P   AT    GE +TS I   +SGS  T+ +  +
Sbjct: 1112 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSGSTETTALPGS 1168

Query: 1127 T 1127
            T
Sbjct: 1169 T 1169



 Score =  108 bits (271), Expect = 3e-23
 Identities = 286/1255 (22%), Positives = 443/1255 (35%), Gaps = 229/1255 (18%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAP-----LMGVPNS-----GALSPPLMPASD--SGA 99
            S + S  G  ST   +S      SAP     L+  P S     G+ +    P S   SG 
Sbjct: 334  SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 393

Query: 100  LSPLLMPASDSGALSPLLMPA-------LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMS 152
                    S   A   +++PA       L   T SP+ S S      PG  T P     S
Sbjct: 394  SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS 453

Query: 153  ATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDS----GELSPILM 208
             T   +P S   +       SSGV  +   +TS S   ST     PDS    G       
Sbjct: 454  TTFHSSPRSPATTLSPASTTSSGV--SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 511

Query: 209  QDMNPGVMSTQPVPA------PSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSG 262
               +PG   T  +PA      PS E+ +    +     A+S    TAL+ G+ S+   S 
Sbjct: 512  SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSN 571

Query: 263  TDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMST 322
              S   ++L   +  S G     T   +S G P   +S   S        +SPG +  ST
Sbjct: 572  PGSTH-TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS--------TSPGLQGEST 622

Query: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWST----- 377
               + P +                              T T P+P S A +P        
Sbjct: 623  AFQTHPAS------------------------------THTTPSPPSTATAPVEESTTYH 652

Query: 378  QNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP-ASGNM-STLQKTVPASG 435
            ++  S   ++ P  +T SG               ST    +P ASG   S+   T    G
Sbjct: 653  RSPGSTPTTHFPASSTTSG-----------HSEKSTIFHSSPDASGTTPSSAHSTTSGRG 701

Query: 436  AMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASG 495
              TTS ++ P S  ++T   S T   +  A  T   +S   PT ++   +     +   G
Sbjct: 702  ESTTSRIS-PGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSPAS---MTSLGVG 756

Query: 496  KMSTPLRRAPTSGAMSTQPVTAT-----------------ASETMSMP-QLTVPASGSMS 537
            + ST  R  P S   +  P + T                 ++ET   P   T    G   
Sbjct: 757  EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 816

Query: 538  MLQMRAPVSEAMSMPQMRTMASGLTSAAQ----MKAMTSGAMSTPLMTAQTSGSTSTLLM 593
                  P S   ++    +  SGLT  +       A T   +   L TA     ++T   
Sbjct: 817  TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 876

Query: 594  RDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTV---- 649
               ++G    P  RS  SG + +   TP       TE  T   S   P+L  + T     
Sbjct: 877  SSGSTGTKLSP-ARSTTSGLVGE--STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 933

Query: 650  --SGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM--TATVSGGMSMPLMRAQDPGVM 705
              S   ++   T T+SG    S    +  G+  T+    + T S     P       G  
Sbjct: 934  PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST 993

Query: 706  PASLMRAKVSGKMLSQPMST--QDPGG--MSMSPMKSMTAGGMQMNSPTSD------VMS 755
             A+L     +   L Q  +T    PG    ++ P  ++T+G ++ ++PT           
Sbjct: 994  EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 1053

Query: 756  TP-------------TVRAWTSETMSTPLMRTSDPG--ERPSLLTRASSSGEMSLPLMRA 800
            TP             T ++W S + +TP    S PG    P  ++    S   S P    
Sbjct: 1054 TPASSTSAGLQEESTTFQSWPSSSDTTP----SPPGTTAAPVEVSTTYHSRPSSTPTTHF 1109

Query: 801  PAS------GEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAM-SMPLTRST 853
             AS       E +T + S      +A   T +A+ ++   P      SG+  +  L  ST
Sbjct: 1110 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 1169

Query: 854  ASGGMS------MPLMRAPD-------------SRVTSTSQMMP-----TASGDMCTLP- 888
             + G+S          R+PD             S  ++TS   P     TA     T+P 
Sbjct: 1170 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1229

Query: 889  VRAPASGGVSSP----LVRAPASGTMS-------TPLRRPSACE-------TVSTELMRA 930
            V   ++   SSP       +P S T S       T    P + E       T ++ L+ A
Sbjct: 1230 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1289

Query: 931  SASGHMSTA--QTTAMVSG-----GMSKPLMRAPAS-GTMPMPLMSAMASGEMSMPLMET 982
            S   H ST    TT   +G     G S      P+S  TMP P  +  A  E+S     T
Sbjct: 1290 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELS-----T 1344

Query: 983  MASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPM 1042
             + G+ S+  T+  ++ S +L ++  + +   +      + S ARST+      SG +  
Sbjct: 1345 TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT------SGLVEE 1398

Query: 1043 PLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMST-PQTAFGVMSTPEIKATD 1101
                 ++ G    M  P+ +    R   +    +S   T+S+ P T   ++  P    + 
Sbjct: 1399 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1458

Query: 1102 SGEASTSHI--NITASGSKPTSHMTATTPET--AKPPPKEVPSFGMLTPALCYLL 1152
             G  +T+H   + T SG    S  + ++P+T    P P    + G +  +  + +
Sbjct: 1459 PGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 1513


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  105 bits (263), Expect = 2e-22
 Identities = 216/976 (22%), Positives = 358/976 (36%), Gaps = 153/976 (15%)

Query: 286  TSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEA 345
            T+T ++G   TP          +S L ++P  +V++T   + P        P  +P    
Sbjct: 1918 TTTASTGSTATP----------TSTLRTAPPPKVLTTTA-TTPTVTSSKATPSSSPGTAT 1966

Query: 346  MSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRA 405
              PAL +   +    T   P P S   + W+  +      +  P    ++   S+ P  A
Sbjct: 1967 ALPALRSTATTPTA-TSVTPIPSSSLGTTWTRLS-----QTTTPTATMSTATPSSTPETA 2020

Query: 406  LDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMS---ATASRV 462
              S  ++       A+G+++T   T     A TT + T  ++G  +T   S   A    V
Sbjct: 2021 HTSTVLTATATTTGATGSVATPSST--PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 2078

Query: 463  MSAQLTMAKTSGAMPTGSM-------KAVAKQYKRATASGKMSTPLRRAPTSG---AMST 512
              +  T   T G+  T S          V        A+G M+TP     TSG   +++T
Sbjct: 2079 WISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTT 2138

Query: 513  QPVTATASETMSMPQ---------------LTVPASGSMSMLQMRA-------PVSEAMS 550
               T TA+ + + P                 T PA+ S ++    A       PV   M+
Sbjct: 2139 TATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMA 2198

Query: 551  MPQMRTM--ASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRS 608
                R++  +S  T      + TSG + T  +T + S  TS  L   T +   S P + S
Sbjct: 2199 TTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT-EPSTVTSHTLAATTGTTQHSTPALSS 2257

Query: 609  LASGALSKPLMTPKASGTM---FTEKMTTTASEAMPTLLMRDTV--SGALSMPQMTDTAS 663
                  S+   +P + GT     T   + T + A P+     T+  S   S P  T    
Sbjct: 2258 PHPS--SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2315

Query: 664  G---------GLSASLMRDTASGAMSTSQMTATVSGGM--SMPL---MRAQ-DPGVMPAS 708
            G          L  S      SG    +      +GG     PL    RAQ  PGV    
Sbjct: 2316 GCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRE 2375

Query: 709  LMRAKVSGKMLSQPMSTQDP-------------------GGMSMSPMKSMTAGGMQMNSP 749
            L +              ++                    G    +P  S TA  M  ++P
Sbjct: 2376 LGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA--MPSSTP 2433

Query: 750  -TSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIAT 808
             T+ +++  T  A T+E+  +    +S PG    +LT  S++  +++P      +G  AT
Sbjct: 2434 GTTWILTELTTTATTTESTGSTATPSSTPGTT-WILTEPSTTATVTVP------TGSTAT 2486

Query: 809  PLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDS 868
               + A         TAT   + SS     +    A ++P  RSTA+   +      P S
Sbjct: 2487 ASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSS 2546

Query: 869  RVTSTSQMMPTASGDMCTLPVRAPASGG--------VSSPLVRAPASGTMSTPLRRPSAC 920
             + +T   +   +    T+    P+S          +++      A+G+++TP   P   
Sbjct: 2547 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTA 2606

Query: 921  E-----TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMR----APAS--GTMPMPLM-- 967
                  T +T    A+ S    TA+T  +     + P  R     P+S  GT   P +  
Sbjct: 2607 HTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLT 2666

Query: 968  ---SAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPI----- 1019
               + +A+G M+ P   T  SG   +L T+   + +++ + +T   S    T PI     
Sbjct: 2667 TTTTTVATGSMATPSSSTQTSGTPPSLTTT---ATTITATGSTTNPSSTPGTTPIPPVLT 2723

Query: 1020 -RASASGARSTSFMRASVSGSM---PMPLPRATASGCGMGMSMPQ-----MTATDSRGMS 1070
              A+   A S++   +S  G+    P+P   AT  G  +  S P       T+  S  + 
Sbjct: 2724 TTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG 2783

Query: 1071 TPLMRASGPGTMSTPQTAFGVM--STPEIKATDSGEASTSHINITASGSKPTSHMTATTP 1128
            T  +     GT  TP    G    STP + +      +T   +  + G+    H  AT+ 
Sbjct: 2784 TTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTE--SPPSPGTTTPGHTRATSR 2841

Query: 1129 ETAKPPPKEVPSFGML 1144
             TA   P +  +  +L
Sbjct: 2842 TTATATPSKTRTSTLL 2857



 Score =  104 bits (260), Expect = 5e-22
 Identities = 246/1171 (21%), Positives = 406/1171 (34%), Gaps = 161/1171 (13%)

Query: 82   PNSGALSPPLMPASDSGA---LSPLLMPASDSGALSPLLMPALDSGTLSP---LLSTSEY 135
            P++ A S    P+S  G    L+     A+ +       +P+   GT  P   L ST+  
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTA-- 3032

Query: 136  GVMSPGMMTIPDFGTMSATLMVAPDSAEISPL--AMPAPSSGVVCTPIMSTSSSEAMSTP 193
                    T P   +  AT   +P +A   P+  +    S+    TPI S +     + P
Sbjct: 3033 --------TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLP 3084

Query: 194  LMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASG 253
                     +S I     +P   S+ P    +S  ++    T   T +MS    T   + 
Sbjct: 3085 EQTTTPMATMSTI-----HP---SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTW 3136

Query: 254  EISSLLMSGTDSEAISSLIMSAVASGGT------SPQPTSTQNSGGIPTPLMSDLDSGIM 307
             ++ L  + T + A       +   G T      S   T T  +G   T   +   +G +
Sbjct: 3137 ILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTL 3196

Query: 308  SSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQ----- 362
              L  ++    V+S+        G  + LP     A   +   +TA+PS  + T      
Sbjct: 3197 KVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLS 3256

Query: 363  --TMPAPGSGAMSPWSTQNV--DSEMMSNPPVRATASGVMSAP---PVRALDSGAMSTPL 415
              T P       +P ST      S +++       A+G ++ P   P  A  +   +T  
Sbjct: 3257 QTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTT 3316

Query: 416  MGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGA 475
             G  A+ + S      P     TT+  T   S V  +     T +  +    T    +G+
Sbjct: 3317 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS 3376

Query: 476  MPT--------GSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQ 527
            M T        G+  ++       TA+G  + P   + T G     PV  T + T +   
Sbjct: 3377 MATPSSSTQTSGTPPSLTTTATTITATGSTTNP---SSTPGTTPIPPVLTTTATTPAATS 3433

Query: 528  LTVPASGSMSMLQMRAPVSEAMSMPQMRTM--ASGLTSAAQMKAMTSGAMSTP------L 579
             TV  S ++       PV    +    R++  +S  T      + TSG + T        
Sbjct: 3434 STVTPSSALGTTHT-PPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 3492

Query: 580  MTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEA 639
            +T+ T  +T++     T +     P  R+  S             GT  T    T +   
Sbjct: 3493 VTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 3552

Query: 640  MPTLLMRDTVSGALSMPQMTDTA-----SGGLSASLMRDTASGAMSTSQMTATVSGGM-- 692
              TLL     S  ++    T        S  L  S      SG    +      +GG   
Sbjct: 3553 TSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVC 3612

Query: 693  SMPL---MRAQ-DPGVMPASLMRAKVSGKMLSQPMSTQDP-------------------G 729
              PL    RAQ  PGV    L +              ++                    G
Sbjct: 3613 EQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYG 3672

Query: 730  GMSMSPMKSMTAGGMQMNSP-TSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRAS 788
                +P  S TA     ++P T+ +++  T  A T+E+  +    +S PG    +LT  S
Sbjct: 3673 HCPSTPATSSTA--TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTT-WILTEPS 3729

Query: 789  SSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMP 848
            ++  +++P      +G  AT   + A         TAT   + SS     +    A ++P
Sbjct: 3730 TTATVTVP------TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALP 3783

Query: 849  LTRSTASGGMSMPLMRAPDSRVTSTSQMM-----PTASGDMCT---LPVRAPASGGVSSP 900
              RSTA+   +      P S + +T   +     PTA+    T    P  A  S  +++ 
Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843

Query: 901  LVRAPASGTMSTPLRRPSACETV-----STELMRASASGHMSTAQT---------TAMVS 946
                 A+G+++TP   P    T      +T     + S    TA+T         T   S
Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTS 3903

Query: 947  GGMSKPLMRAPASGTMPMPLM-----SAMASGEMSMPLMETMASGATSTLQTSVANSRSM 1001
            G    P   +   GT   P +     + +A+G M+ P   T  SG   +L T+     + 
Sbjct: 3904 GSTVTP---SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITAT 3960

Query: 1002 SLSQTTYTVSGRMATAPI---RASASGARSTSFMRASVSGSMPMP-LPRATASGCGMGMS 1057
              +    +  G     P+    A+   A S++   +S  G+   P +P  TA+  G  +S
Sbjct: 3961 GSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLS 4020

Query: 1058 MPQMTATDSRGMSTPLMRASGPGTMSTPQTAF--GVMSTPEIKATDSGEASTSHINITAS 1115
                               S P T+ T  T+   G + T  I    +G   TSH     +
Sbjct: 4021 ------------------PSSPHTVRTAWTSATSGTLGTTHITEPSTG---TSHTPAATT 4059

Query: 1116 GSKPTSHMTATTPETAKPPPKEVPSFGMLTP 1146
            G+   S    ++P  +    +  PS G  TP
Sbjct: 4060 GTTQHSTPALSSPHPSSRTTESPPSPGTTTP 4090



 Score =  103 bits (257), Expect = 1e-21
 Identities = 238/1148 (20%), Positives = 408/1148 (35%), Gaps = 142/1148 (12%)

Query: 52   STSASDPGGT-------STQLMTSPVFDTMSAP----LMGVPNSGALSPPLMPASDSGAL 100
            +T +S PG T       +T  +T P   T +A       G P+    +    P   S   
Sbjct: 2456 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT--PTVTSSKA 2513

Query: 101  SPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
            +P   P + +       +PAL S   +P  +TS   + S  + T     + + T      
Sbjct: 2514 TPFSSPGTATA------LPALRSTATTPT-ATSFTAIPSSSLGTTWTRLSQTTTPTATMS 2566

Query: 161  SAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQP 220
            +A  S       +S V+ T   +T ++ +++TP    P +   + +L      G  +T P
Sbjct: 2567 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSS-TPGTAHTTKVLTTTTT-GFTAT-P 2623

Query: 221  VPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
              +P +    P+ I+   T        T   S    S +   T +  + +   + VA+G 
Sbjct: 2624 SSSPGTARTLPVWISTTTTP-------TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS 2676

Query: 281  TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPA 340
             +   +STQ SG    P ++   + I ++   ++P S   +TP+  V      +T   PA
Sbjct: 2677 MATPSSSTQTSG--TPPSLTTTATTITATGSTTNPSSTPGTTPIPPV----LTTTATTPA 2730

Query: 341  PDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSA 400
              +  ++P+      S +  T T P P + A +   + +  S         +  SG +  
Sbjct: 2731 ATSSTVTPS------SALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGT 2784

Query: 401  PPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTV---PSSGVMSTEQMSA 457
              +    +G   TP      +    T Q + PA  +   S  T    PS G  +     A
Sbjct: 2785 THITEPSTGTSHTP------AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRA 2838

Query: 458  TASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTA 517
            T+    +A  +  +TS  +P                S   S P+    T G    +P  A
Sbjct: 2839 TSRTTATATPSKTRTSTLLP----------------SSPTSAPITTVVTMGC---EPQCA 2879

Query: 518  TASETMSMPQLTVPASGSM-SMLQMRAPVSEAMSMP---QMRTMASGLTSAAQMKAMTSG 573
             +        +  P+ G   +   +RA        P   + R  A       ++  +   
Sbjct: 2880 WSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVEC 2939

Query: 574  AMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGT--MFTEK 631
            ++   L+           +  +    V  C      ++ A S         GT  + TE+
Sbjct: 2940 SLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQ 2999

Query: 632  MT--TTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVS 689
             T  TT +    T +   T   A     +T TA+   + S     +    S+S  TAT  
Sbjct: 3000 TTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-----SKATSSSSPRTATTL 3054

Query: 690  GGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSP 749
              ++    ++      P        +G +   P  T  P    M+ M ++        + 
Sbjct: 3055 PVLTSTATKSTATSFTPIPSFTLGTTGTL---PEQTTTP----MATMSTIHPSSTPETTH 3107

Query: 750  TSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATP 809
            TS V++T       + +MSTP   +S PG    L        E++       A+G  ATP
Sbjct: 3108 TSTVLTTKATTTRATSSMSTP---SSTPGTTWILT-------ELTTAATTTAATGPTATP 3157

Query: 810  LRSP-AYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDS 868
              +P     ++ P  TAT          V  P     +   TR+TA G + +    A   
Sbjct: 3158 SSTPGTTWILTEPSTTAT----------VTVPTGSTATASSTRATA-GTLKVLTSTATTP 3206

Query: 869  RVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELM 928
             V S+     ++ G    LP     +   ++  V A  S ++ T   R S   T +  + 
Sbjct: 3207 TVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3266

Query: 929  RASASGH---------MSTAQTTAMVSGGMSKPLMRAPASGTMPMPL-----MSAMASGE 974
             A+ S           ++T  TT   +G ++ P      + T  +P       +A  S  
Sbjct: 3267 TATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 3326

Query: 975  MSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRA 1034
                L   +    T+T  T  +     S+  TT+T +  + T      A+G+ +T     
Sbjct: 3327 PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT--VLTTTTTTVATGSMATPSSST 3384

Query: 1035 SVSGSMPMPLPRA---TASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGV 1091
              SG+ P     A   TA+G     S    T      ++T     +   +  TP +A G 
Sbjct: 3385 QTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGT 3444

Query: 1092 MSTPEI---KATDSGEA---STSHINITA-----SGSKPTSHMTATTPETAKPPPKEVPS 1140
              TP +    AT  G +   S+ H   TA     SG   T+H+T  +  T+  P     +
Sbjct: 3445 THTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST 3504

Query: 1141 FGMLTPAL 1148
                TPAL
Sbjct: 3505 TQHSTPAL 3512



 Score =  103 bits (256), Expect = 1e-21
 Identities = 224/1126 (19%), Positives = 391/1126 (34%), Gaps = 114/1126 (10%)

Query: 53   TSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGA 112
            T +S PG T T  + +    T++   M  P+S   +        SG    L+  A+   A
Sbjct: 3908 TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT--------SGTPPSLITTATTITA 3959

Query: 113  LSPLLMPALDSGT--LSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                  P+   GT  + P+L+T+     +      P     +      P++   +     
Sbjct: 3960 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSL 4019

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGE-----LSPILMQDMNPGVMSTQPVPAPS 225
            +PSS        ++++S  + T  +  P +G       +    Q   P + S  P    +
Sbjct: 4020 SPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTT 4079

Query: 226  SEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQP 285
                SP   T   T A S+   TA  S   +S L+  + + A     ++ V + G  PQ 
Sbjct: 4080 ESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAP----ITTVVTTGCEPQC 4135

Query: 286  TSTQ---NSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPD 342
              ++    S  +P P   D D+   S++   + G  V   PL       E     +P   
Sbjct: 4136 AWSEWLDYSYPMPGPSGGDFDT--YSNI--RAAGGAVCEQPL-----GLECRAQAQPGVP 4186

Query: 343  AEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPP 402
               +   +  +L  G++                  Q    +M  N  +R         P 
Sbjct: 4187 LGELGQVVECSLDFGLVCRNR-------------EQVGKFKMCFNYEIRVFCCNYGHCPS 4233

Query: 403  VRALDSGAMSTPLMGAP-ASGNMSTLQKTVPASGAMTTSLMT---VPSSGVMSTEQMSAT 458
              A  S AM +   G       ++T   T  ++G+  T   T    P   V+++   + T
Sbjct: 4234 TPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPT 4293

Query: 459  ASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTAT 518
            A+   +   +  +T+  +P  +  A      ++TA+     P     T+G +  Q  T  
Sbjct: 4294 ATSSKATSSSSPRTATTLPVLTSTAT-----KSTATSVTPIPSSTLGTTGTLPEQTTTPV 4348

Query: 519  ASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLT--SAAQMKAMTSGAMS 576
            A+ +   P  T   + + ++L  +A  + A S     +   G T        A T+ A +
Sbjct: 4349 ATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAAT 4408

Query: 577  TPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTA 636
             P  T  ++  T+ +L   T +   +       ++G+ + P  TP    T    + +TTA
Sbjct: 4409 GPTATPSSTPGTTWILTELTTTATTTA------STGSTATPSSTPGT--TWILTEPSTTA 4460

Query: 637  SEAMPT--LLMRDTVSGALSMPQMTDTASGGLSASLMRDTASG-----AMSTSQMTATVS 689
            +  +PT       +       P ++ TA+     S     +S      A+   + TAT  
Sbjct: 4461 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTP 4520

Query: 690  GGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSP 749
               S   + +   G     L +       +S    +  P  +  S + + TA        
Sbjct: 4521 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGS 4580

Query: 750  TSDVMSTPTVRAWTSETMSTPLMRTSDPGERP-SLLTRASSSGEMSLPLMRAPA-SGEIA 807
             +   STP     T    +T    T+ P   P + LT        + P    P  SG   
Sbjct: 4581 VATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTV 4640

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPD 867
            TP         S P  T TA  + ++   V    +G+M+ P + +  SG         P 
Sbjct: 4641 TP--------SSIPGTTHTARVLTTTTTTVA---TGSMATPSSSTQTSG--------TPP 4681

Query: 868  SRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTEL 927
            S  T+ + +  T S    T P   P +  ++  L     +   ++     S+    +T L
Sbjct: 4682 SLTTTATTITATGS---TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTL 4738

Query: 928  MRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGA 987
               +++   STA +   +           PA  T PM  MS + +         T  +  
Sbjct: 4739 PVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTS-------STPETTH 4791

Query: 988  TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRA 1047
            TST+ T+ A       + +T T S  + T  I    +   +T+    S +     P    
Sbjct: 4792 TSTVLTTTAT--MTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTP---- 4845

Query: 1048 TASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKAT---DSGE 1104
               G    ++ P   AT      +    +S  GT  TP+    + + P   A+    S  
Sbjct: 4846 ---GTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSST 4902

Query: 1105 ASTSHINITASGSKPT-SHMTATTPETAKPPPKEVPSFGMLTPALC 1149
              T+        S PT S  T ++       P   PS    TP  C
Sbjct: 4903 VGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFC 4948



 Score =  102 bits (254), Expect = 3e-21
 Identities = 246/1173 (20%), Positives = 437/1173 (37%), Gaps = 165/1173 (14%)

Query: 82   PNSGALSPPLMPASDSGA---LSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVM 138
            P++ A S   MP+S  G    L+ L   A+ + +      P+   GT   L   S     
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPS----- 2472

Query: 139  SPGMMTIPDFGTMSATLMVAP---------------DSAEISPLAMPAPSSGVVCTPIMS 183
            +   +T+P   T +A+   A                 S++ +P + P  ++ +   P + 
Sbjct: 2473 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATAL---PALR 2529

Query: 184  TSSSEAMSTPLMLAPDS--GELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEA 241
            ++++   +T     P S  G     L Q   P   +T     PSS        T E    
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTP--TATMSTATPSS--------TPETVHT 2579

Query: 242  MSKVLMTALASGEISSLLM-SGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIP----- 295
             + +  TA  +G   S+   S T   A ++ +++   +G T+   +S   +  +P     
Sbjct: 2580 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIST 2639

Query: 296  TPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPAL----- 350
            T   +   S +  S +  +  +  + T   +    G M+T P  +       P+L     
Sbjct: 2640 TTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMAT-PSSSTQTSGTPPSLTTTAT 2698

Query: 351  -MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVR-ATASGVMSAPPVRALDS 408
             +TA  S   P+ T   PG+  + P  T    +   ++  V  ++A G    PPV    +
Sbjct: 2699 TITATGSTTNPSST---PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTA 2755

Query: 409  GAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASR----VMS 464
                  L  +P+S +      T   SG + T+ +T PS+G   T   +   ++     +S
Sbjct: 2756 TTHGRSL--SPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALS 2813

Query: 465  AQLTMAKTSGAMPT------GSMKAVAKQYKRATASG-KMSTPLRRAPTSGAMST----- 512
            +    ++T+ + P+      G  +A ++    AT S  + ST L  +PTS  ++T     
Sbjct: 2814 SPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMG 2873

Query: 513  -QPVTATASETMSMPQLTVPASGSMSMLQ-MRAPVSEAMSMP---QMRTMASGLTSAAQM 567
             +P  A +        +  P+ G       +RA        P   + R  A       ++
Sbjct: 2874 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLREL 2933

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGT- 626
              +   ++   L+           +  +    V  C      ++ A S         GT 
Sbjct: 2934 GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTT 2993

Query: 627  -MFTEKMT--TTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQ 683
             + TE+ T  TT +    T +   T   A     +T TA+   + S     +    S+S 
Sbjct: 2994 WILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-----SKATSSSSP 3048

Query: 684  MTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQ---PMSTQDPGGMSMSPMKSMT 740
             TAT    ++    ++      P        +G +  Q   PM+T      S +P  + T
Sbjct: 3049 RTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHT 3108

Query: 741  AGGMQMNSPTSDV---MSTPTVR---AW------TSETMSTPLMRTSDPGERPS---LLT 785
            +  +   + T+     MSTP+      W      T+ T +     T+ P   P    +LT
Sbjct: 3109 STVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILT 3168

Query: 786  RASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAM 845
              S++  +++P      S   A+  R+ A G +     TAT   ++SS     +    A 
Sbjct: 3169 EPSTTATVTVPT----GSTATASSTRATA-GTLKVLTSTATTPTVISSRATPSSSPGTAT 3223

Query: 846  SMPLTRSTASGGMSMPLMRAPDSRV----TSTSQ-MMPTASGDMCT---LPVRAPASGGV 897
            ++P  RSTA+   +  +   P S +    T  SQ   PTA+    T    P     S  +
Sbjct: 3224 ALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVL 3283

Query: 898  SSPLVRAPASGTMSTPLRRPSACE-----TVSTELMRASASGHMSTAQTTAMVSGGMSKP 952
            ++      A+G+++TP   P         T +T    A+ S    TA T  +     + P
Sbjct: 3284 TTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTP 3343

Query: 953  LMR----APAS-------GTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSM 1001
              R     P+S        T+     + +A+G M+ P   T  SG   +L T+   + ++
Sbjct: 3344 TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTT---ATTI 3400

Query: 1002 SLSQTTYTVSGRMATAPI------RASASGARSTSFMRASVSGSMPMPLPRATASGCGMG 1055
            + + +T   S    T PI       A+   A S++   +S  G+   P            
Sbjct: 3401 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTP------------ 3448

Query: 1056 MSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITAS 1115
              +P  TAT + G S P      P +  T +TA+   ++  +  T   E ST   +  A+
Sbjct: 3449 -PVPNTTAT-THGRSLP------PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA 3500

Query: 1116 GSKPTSHMT--ATTPETAKPPPKEVPSFGMLTP 1146
             +  T H T   ++P  +    +  PS G  TP
Sbjct: 3501 TTSTTQHSTPALSSPHPSSRTTESPPSPGTTTP 3533



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 241/1113 (21%), Positives = 401/1113 (36%), Gaps = 160/1113 (14%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGAL---SPLL 104
            LP + ++A+ P  TS   + S    T    L       A      P+S    +   + L 
Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 2584

Query: 105  MPASDSGALSPLLMPALDSGTL--SPLLSTSEYGVM-----SPGMM-TIPDFGTMSATLM 156
              A+ +GA   +  P+   GT   + +L+T+  G       SPG   T+P +  +S T  
Sbjct: 2585 TTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVW--ISTTTT 2642

Query: 157  VAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVM 216
                 + ++P ++P    G   TP + T+++  ++T  M  P S   +      +     
Sbjct: 2643 PTTRGSTVTPSSIP----GTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTAT 2698

Query: 217  S-------TQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAIS 269
            +       T P   P +  + P+  T   T A +   +T       S+L  + T     +
Sbjct: 2699 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPS-----SALGTTHTPPVPNT 2753

Query: 270  SLIMSAVASGGTSPQPTSTQ----NSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLL 325
            +      +   +SP    T      SG + T  +++  +G  S    ++ G+   STP L
Sbjct: 2754 TATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGT-SHTPAATTGTTQHSTPAL 2812

Query: 326  SVPDAGEMSTLPKPAPDA------EAMSPALMTALPSG-----VMPTQTMPAP------- 367
            S P     +T   P+P         A S    TA PS      ++P+    AP       
Sbjct: 2813 SSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2872

Query: 368  GSGAMSPWSTQNVDSEMMSNPP---------VRATASGVMSAPPVRALDSGAMSTPLMGA 418
            G      WS     S  M  P          +RA    V   P    L+  A + P  G 
Sbjct: 2873 GCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP--LGLECRAQAQP--GV 2928

Query: 419  PASGNMSTLQKTVPAS---GAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGA 475
            P    +  L + V  S   G +  +   V    +    ++            T A +S A
Sbjct: 2929 P----LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA 2984

Query: 476  MPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS 535
             P+ +        ++ TA+   +T    A  S    T P     + T + P  T   + S
Sbjct: 2985 TPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATS 3044

Query: 536  MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRD 595
             S              P+  T    LTS A     TS    TP+ +  T G+T TL  + 
Sbjct: 3045 SSS-------------PRTATTLPVLTSTATKSTATS---FTPIPSF-TLGTTGTLPEQT 3087

Query: 596  TAS-GVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALS 654
            T     MS     S      +  ++T KA+ T  T  M+T +S    T ++ +  + A +
Sbjct: 3088 TTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147

Query: 655  M----PQMTDTASGGLSASLMRDTAS-------GAMSTSQMTATVSGGMSMPLMRAQDPG 703
                 P  T +++ G +  L   + +       G+ +T+  T   +G + +    A  P 
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207

Query: 704  VMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWT 763
            V+              S+   +  PG  +  P    TA      S T+ + S+    AWT
Sbjct: 3208 VIS-------------SRATPSSSPGTATALPALRSTATTPTATSVTA-IPSSSLGTAWT 3253

Query: 764  ---SETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSA 820
                 T  T  M T+ P   P  +    +S  ++       A+G +ATP  +P  G    
Sbjct: 3254 RLSQTTTPTATMSTATPSSTPETV---HTSTVLTTTTTTTRATGSVATPSSTP--GTAHT 3308

Query: 821  PQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTA 880
             ++  T +   ++ P        A++ P+  ST +     P  R   S VT +S    T 
Sbjct: 3309 TKVPTTTTTGFTATPSSSP--GTALTPPVWISTTT----TPTTRG--STVTPSSIPGTTH 3360

Query: 881  SGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTA- 939
            +  + T      A+G +++P      SGT       PS   T +T     S +   ST  
Sbjct: 3361 TATVLTTTTTTVATGSMATPSSSTQTSGTP------PSLTTTATTITATGSTTNPSSTPG 3414

Query: 940  --------QTTAMVSGGMSKPLMRAPASGTM---PMPLMSAMASGEMSMPLMETMASGAT 988
                     TTA      S  +  + A GT    P+P  +A   G    P        + 
Sbjct: 3415 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPP-------SSP 3467

Query: 989  STLQTSVANSRSMSLSQTTYTVSGRMAT-APIRASASGARSTSFMRASVSGSMPM---PL 1044
             T++T+  ++ S  L  T  T    + +  P   +++   ST  + +    S      P 
Sbjct: 3468 HTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPS 3527

Query: 1045 PRATASGCGMGMSMPQMTATDSRGMSTPLMRAS 1077
            P  T  G   G S    TAT S+  ++ L+ +S
Sbjct: 3528 PGTTTPGHTRGTSRTTATATPSKTRTSTLLPSS 3560



 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 243/1111 (21%), Positives = 396/1111 (35%), Gaps = 150/1111 (13%)

Query: 49   PIVSTSASDPGGTSTQLMTSPVFDT----------MSAPLMGVPNSGALSPPLMPASDSG 98
            P+ + S   P  T     TS V  T          MS P      +  L+     A+ + 
Sbjct: 3090 PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTA 3149

Query: 99   ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVA 158
            A  P   P+S  G    L  P+  +    P  ST      +    T    GT+      A
Sbjct: 3150 ATGPTATPSSTPGTTWILTEPSTTATVTVPTGST------ATASSTRATAGTLKVLTSTA 3203

Query: 159  PDSAEISPLAMPAPSSG-VVCTPIMSTSSSEAMSTPLMLAPDS--GELSPILMQDMNPGV 215
                 IS  A P+ S G     P + ++++   +T +   P S  G     L Q   P  
Sbjct: 3204 TTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTA 3263

Query: 216  MSTQPVPAPSSEAM---SPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLI 272
              +   P+ + E +   + L  T   T A   V   +   G   +  +  T +   ++  
Sbjct: 3264 TMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 3323

Query: 273  MSAVASGGTSPQPTSTQNS----GGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
             S+  +  T P   ST  +    G   TP  S +     ++ ++++  + V +T  ++ P
Sbjct: 3324 SSSPGTALTPPVWISTTTTPTTRGSTVTP--SSIPGTTHTATVLTTTTTTV-ATGSMATP 3380

Query: 329  DAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNP 388
             +   ST     P +   +   +TA  S   P+ T   PG+  + P  T    +   ++ 
Sbjct: 3381 SS---STQTSGTPPSLTTTATTITATGSTTNPSST---PGTTPIPPVLTTTATTPAATSS 3434

Query: 389  PVR-ATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS- 446
             V  ++A G    PPV    +      L   P+S +      T   SG + T+ +T PS 
Sbjct: 3435 TVTPSSALGTTHTPPVPNTTATTHGRSL--PPSSPHTVRTAWTSATSGILGTTHITEPST 3492

Query: 447  ------SGVMSTEQMS--ATASRVMSAQLTMAKTS-GAMPTGSMKAVAKQYKRATAS-GK 496
                  +   ST Q S  A +S   S++ T +  S G    G  +  ++    AT S  +
Sbjct: 3493 VTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 3552

Query: 497  MSTPLRRAPTSGAMST------QPVTATASETMSMPQLTVPASGSM-SMLQMRAPVSEAM 549
             ST L  +PTS  ++T      +P  A +        +  P+ G   +   +RA      
Sbjct: 3553 TSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVC 3612

Query: 550  SMP---QMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQM 606
              P   + R  A       ++  +   ++   L+           +  +    V  C   
Sbjct: 3613 EQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYG 3672

Query: 607  RSLASGALSKPLMTPKASGTMF-TEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGG 665
               ++ A S         GT +   K+TTTA+    T        G+ + P  T   +  
Sbjct: 3673 HCPSTPATSSTATPSSTPGTTWILTKLTTTATTTEST--------GSTATPSSTPGTTWI 3724

Query: 666  LSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMST 725
            L+      TA+  + T   TAT S   +     A  P V   +      S K  + P S+
Sbjct: 3725 LTEP--STTATVTVPTGS-TATASSTQA----TAGTPHVSTTATTPTVTSSK--ATPFSS 3775

Query: 726  QDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWT---SETMSTPLMRTSDPGERPS 782
              PG  +  P    TA      S T+ + S+     WT     T  T  M T+ P   P 
Sbjct: 3776 --PGTATALPALRSTATTPTATSFTA-IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 3832

Query: 783  LLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPIS 842
                A +S  ++       A+G +ATP  +P                   +    K P +
Sbjct: 3833 ---TAHTSTVLTTTATTTRATGSVATPSSTP------------------GTAHTTKVPTT 3871

Query: 843  GAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLV 902
                  +T S++ G       R P   +++T+   PT SG   T P   P  G   +P V
Sbjct: 3872 TTTGFTVTPSSSPG-----TARTPPVWISTTT--TPTTSGSTVT-PSSVP--GTTHTPTV 3921

Query: 903  RAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTM 962
                + T++T      +  T S+    +     + T  TT   +G  + P   +   GT 
Sbjct: 3922 LTTTTTTVAT-----GSMATPSSSTQTSGTPPSLITTATTITATGSTTNP---SSTPGTT 3973

Query: 963  PMP---LMSAMASGEMSMPLMETMASGATST----LQTSVANSRSMSLSQT-------TY 1008
            P+P     +A      S  +  + A G T T      T+  + RS+S S         T 
Sbjct: 3974 PIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTS 4033

Query: 1009 TVSGRMATAPIRASASGARSTSFMRASVSG---------SMPMPLPRATASGCGMGMSMP 1059
              SG + T  I   ++G   TS   A+ +G         S P P  R T S    G + P
Sbjct: 4034 ATSGTLGTTHITEPSTG---TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 4090

Query: 1060 QMTATDSRGMSTPLMRASGPGTM--STPQTA 1088
              T   SR  +T     +   T+  S+P +A
Sbjct: 4091 GHTTATSRTTATATPSKTRTSTLLPSSPTSA 4121



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 255/1240 (20%), Positives = 439/1240 (35%), Gaps = 192/1240 (15%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASD---SGALSPLL 104
            LP + ++A+ P  TS   + S    T    L       A      P+S    +   + L 
Sbjct: 1968 LPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLT 2027

Query: 105  MPASDSGALSPLLMPALDSGTLS----PLLSTSEYGVM---SPGMMTIPDFGTMSATLMV 157
              A+ +GA   +  P+   GT      P  +T+ +      SPG    P    +S T   
Sbjct: 2028 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVW-ISTTTTP 2086

Query: 158  APDSAEISPLAMPAPS-SGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQ--DMNPG 214
                + ++P ++P  + +  V T   +T ++ +M+TP      SG    +      +   
Sbjct: 2087 TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITAT 2146

Query: 215  VMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMT---ALASGEISSL--LMSGTDSEAIS 269
              +T P   P +  + P+  T   T A +   +T   AL +     +   M+ T   ++ 
Sbjct: 2147 GSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLP 2206

Query: 270  SLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPD 329
                  V +  TS        SG + T  +++  S + S  L ++ G+   STP LS P 
Sbjct: 2207 PSSPHTVRTAWTSA------TSGILGTTHITE-PSTVTSHTLAATTGTTQHSTPALSSPH 2259

Query: 330  AGEMSTLPKPAP------DAEAMSPALMTALP-----SGVMPTQTMPAP-------GSGA 371
                +T   P+P         A S    TA P     S ++P+    AP       G   
Sbjct: 2260 PSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEP 2319

Query: 372  MSPWSTQNVDSEMMSNPP---------VRATASGVMSAPPVRALDSGAMSTPLMGAPASG 422
               WS     S  M  P          +RA    V   P    L+  A + P  G P   
Sbjct: 2320 QCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP--LGLECRAQAQP--GVP--- 2372

Query: 423  NMSTLQKTVPAS---GAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPT- 478
             +  L + V  S   G +  +   V    +    ++            T A +S AMP+ 
Sbjct: 2373 -LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSS 2431

Query: 479  --GSMKAVAKQYKRAT---ASGKMSTP--------LRRAPTSGAMSTQPV--TATASETM 523
              G+   + +    AT   ++G  +TP        +   P++ A  T P   TATAS T 
Sbjct: 2432 TPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQ 2491

Query: 524  S---MPQLTVPASGSMSMLQMRAPVSE---AMSMPQMRTMASGLTSAAQMKAMTSGAMST 577
            +    P ++  A+          P S    A ++P +R+ A+  T+ +     +S   +T
Sbjct: 2492 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 2551

Query: 578  PLMTAQTSGSTSTLLMRDTA--------SGVMSCPQMRSLASGALSKPLMTPKASGTMFT 629
                +QT+  T+T+     +        S V++     + A+G+++ P  TP   GT  T
Sbjct: 2552 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP---GTAHT 2608

Query: 630  EKMTTTASEAMPTLLMRDTVSGALSMP-----QMTDTASGG--LSASLMRDTASGAMSTS 682
             K+ TT +    T     +   A ++P       T T  G     +S+   T +  + T+
Sbjct: 2609 TKVLTTTTTGF-TATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTT 2667

Query: 683  QMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAG 742
              T   +G M+ P    Q  G  P+    A       S    +  PG   + P+ + TA 
Sbjct: 2668 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2727

Query: 743  GMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPA 802
                 S T     TP+    T+ T   P    +  G      + + SS         +  
Sbjct: 2728 TPAATSST----VTPSSALGTTHTPPVPNTTATTHGR-----SLSPSSPHTVRTAWTSAT 2778

Query: 803  SGEIATP-LRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMP 861
            SG + T  +  P+ G    P   AT      S P + +P   + +   T S  S G + P
Sbjct: 2779 SGTLGTTHITEPSTGTSHTP--AATTGTTQHSTPALSSPHPSSRT---TESPPSPGTTTP 2833

Query: 862  LMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE 921
                  SR T+T+                 P+    S+ L  +P S  ++T +      +
Sbjct: 2834 GHTRATSRTTATA----------------TPSKTRTSTLLPSSPTSAPITTVVTMGCEPQ 2877

Query: 922  TVSTEL------MRASASGHMSTAQTTAMVSGGM-SKPL---MRAPASGTMPMPLMSAMA 971
               +E       M   + G   T        G +  +PL    RA A   +P+  +  + 
Sbjct: 2878 CAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVV 2937

Query: 972  SGEMSMPLM-----------------------------ETMASGATSTLQTSVANSRSMS 1002
               +   L+                              T A+ +T+T  ++   +  ++
Sbjct: 2938 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILT 2997

Query: 1003 LSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGC-GMGMSMPQM 1061
               T  T +    +  I +S  G      +  S + +      +AT+S       ++P +
Sbjct: 2998 EQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVL 3057

Query: 1062 TATDSRGMSTPLMRASGPGTMSTPQTAFGVMST---PEIKATDSGEASTSHINITASGSK 1118
            T+T ++  +T            TP  +F + +T   PE   T     ST H + T   + 
Sbjct: 3058 TSTATKSTATSF----------TPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTH 3107

Query: 1119 PTSHMTATTPETAKPPPKEVPSFGMLTPALCYLLEEQEAA 1158
             ++ +T     T        PS    TP   ++L E   A
Sbjct: 3108 TSTVLTTKATTTRATSSMSTPS---STPGTTWILTELTTA 3144



 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 245/1184 (20%), Positives = 414/1184 (34%), Gaps = 174/1184 (14%)

Query: 49   PIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALS-----PPLMP--------AS 95
            P+++T+A+ P  TS+ +  S    T   P   VPN+ A +     PP  P        ++
Sbjct: 3420 PVLTTTATTPAATSSTVTPSSALGTTHTP--PVPNTTATTHGRSLPPSSPHTVRTAWTSA 3477

Query: 96   DSGALS------PLLMPASDSGALSPLLM---PALDSGTLSPLLSTS--EYGVMSPGMMT 144
             SG L       P  + +    A +       PAL S   S   + S    G  +PG   
Sbjct: 3478 TSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTR 3537

Query: 145  IPDFGTMSATLMVAPDSAEISPLAMPAPSSGVV-------CTPIMSTSSSEAMSTPLMLA 197
                GT   T    P     S L   +P+S  +       C P  + S     S P M  
Sbjct: 3538 ----GTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP-MPG 3592

Query: 198  PDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEIS- 256
            P  G+           G +  QP+         P          + +V+  +L  G +  
Sbjct: 3593 PSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP----GVPLRELGQVVECSLDFGLVCR 3648

Query: 257  SLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPG 316
            +    G      +  I     + G  P   +T ++    TP  +   + I++ L  ++  
Sbjct: 3649 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA---TPSSTPGTTWILTKLTTTATT 3705

Query: 317  SEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWS 376
            +E   +        G    L +P+  A    P   TA  S    T   P   + A +P  
Sbjct: 3706 TESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 3765

Query: 377  TQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGA 436
            T +  +   S  P  ATA      P +R+  +   +T     P+S   +T  +      +
Sbjct: 3766 TSSKATPFSS--PGTATA-----LPALRSTATTPTATSFTAIPSSSLGTTWTRL-----S 3813

Query: 437  MTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMK---AVAKQYKRATA 493
             TT+     S+   S+   +A  S V++   T  + +G++ T S     A   +    T 
Sbjct: 3814 QTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTT 3873

Query: 494  SGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQ 553
            +G   TP   + + G   T PV  + + T +    TV  S                S+P 
Sbjct: 3874 TGFTVTP---SSSPGTARTPPVWISTTTTPTTSGSTVTPS----------------SVPG 3914

Query: 554  MRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGA 613
                 + LT+     A  +G+M+TP  + QTSG+  +L+   T             A+G+
Sbjct: 3915 TTHTPTVLTTTTTTVA--TGSMATPSSSTQTSGTPPSLITTATT----------ITATGS 3962

Query: 614  LSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALS------MPQMTDTASG-GL 666
             + P  TP   GT     + TT +          T S AL       +P  T T  G  L
Sbjct: 3963 TTNPSSTP---GTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSL 4019

Query: 667  SAS-------LMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKML 719
            S S             SG + T+ +T   +G    P            +L     S +  
Sbjct: 4020 SPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTT 4079

Query: 720  SQPMS--TQDPGGMSMSPMKSMTA-------GGMQMNSPTSDVMSTPTVRAWTSETMSTP 770
              P S  T  PG  + +   + TA         +  +SPTS  ++T        +   + 
Sbjct: 4080 ESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 4139

Query: 771  LMRTSDPGERPS-------LLTRASSSGEMSLPL-MRAPASGEIATPLRSPAYGAMSAPQ 822
             +  S P   PS          RA+       PL +   A  +   PL     G +    
Sbjct: 4140 WLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPL-----GELGQVV 4194

Query: 823  MTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASG 882
              +   G++    +         +  +     + G        P +  TS++ M  +  G
Sbjct: 4195 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYG------HCPSTPATSSTAMPSSTPG 4248

Query: 883  D---MCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTA 939
                +  L   A  +    S    +   GT   P    S   T +    +A++S    TA
Sbjct: 4249 TTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTA 4308

Query: 940  QTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSR 999
             T  +++   +K    + A+   P+P  +   +G  ++P   T      ST+  S     
Sbjct: 4309 TTLPVLTSTATK----STATSVTPIPSSTLGTTG--TLPEQTTTPVATMSTIHPS----- 4357

Query: 1000 SMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMP 1059
              S  +TT+T          +A+ + A S++   +S  G+  + L   T +      + P
Sbjct: 4358 --STPETTHT----STVLTTKATTTRATSSTSTPSSTPGTTWI-LTELTTAATTTAATGP 4410

Query: 1060 QMTATDSRG-------MSTPLMRASGPGTMSTPQTAFG---VMSTPEIKAT---DSGEAS 1106
              T + + G       ++T     +  G+ +TP +  G   +++ P   AT    +G  +
Sbjct: 4411 TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTA 4470

Query: 1107 TSHINITASGSKPTSHMTATTP--ETAKPPPKEVPSFGMLTPAL 1148
            T+  +  A+   P    TATTP   ++K  P   P      PAL
Sbjct: 4471 TAS-STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPAL 4513



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 222/1134 (19%), Positives = 396/1134 (34%), Gaps = 180/1134 (15%)

Query: 125  TLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMST 184
            T +P  ST+    +S G+ T P +   ++TL  A      +P     P+   V T  + T
Sbjct: 1643 TRAPPASTTAVPTLSEGL-TSPRY---TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPT 1698

Query: 185  SSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSK 244
             S+   +T  +     G   P           S  P  AP++ A S  + T   + A  +
Sbjct: 1699 RSALPGTTGSL-----GTWRP-----------SQPPTLAPTTMATSRARPTGTASTASKE 1742

Query: 245  VLMTALASGEISSLLMSGTDSEA------ISSLIMSAVASGGTSPQPTSTQNSGGIPTPL 298
             L T+LA    S L  S  ++        +S L  +  + G T  QP             
Sbjct: 1743 PLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTE------- 1795

Query: 299  MSDLD---SGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALP 355
              D+D   SG+    + +          +   P + E      P    + +   L  +L 
Sbjct: 1796 WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLE 1855

Query: 356  SGVMPTQTMPAPGSGAMSPWSTQNVD-------SEMMSNPPVRATASGVMSAPPVRALD- 407
            +G+          +G  +     NV        S   S P   +TA+   +      L  
Sbjct: 1856 TGLTCKNE---DQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTK 1912

Query: 408  --SGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSA 465
              + A +T   G+ A+   STL +T P    +TT+  T   +   +T   S   +  + A
Sbjct: 1913 PTTTATTTASTGSTATPT-STL-RTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPA 1970

Query: 466  QLTMAKTSGA-----MPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATAS 520
              + A T  A     +P+ S+     +  + T      TP     T+   ST P TA  S
Sbjct: 1971 LRSTATTPTATSVTPIPSSSLGTTWTRLSQTT------TPTATMSTATPSST-PETAHTS 2023

Query: 521  ETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLT-SAAQMKAMTSGAMSTPL 579
              ++    T  A+GS++        +    +P   T     T S++   A+T     +  
Sbjct: 2024 TVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT 2083

Query: 580  MTAQTSGSTST--LLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTAS 637
             T  T GST T   +   T +  +      ++A+G+++ P  + + SGT  +   T T  
Sbjct: 2084 TTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI 2143

Query: 638  EAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM-----TATVSGGM 692
             A  +     +  G   +P +  T +   +A+    T S A+ T+       T   + G 
Sbjct: 2144 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGR 2203

Query: 693  SMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSD 752
            S+P            S     +    +++P +         S   + T G  Q ++P   
Sbjct: 2204 SLPPSSPHTVRTAWTSATSGILGTTHITEPSTV-------TSHTLAATTGTTQHSTP--- 2253

Query: 753  VMSTPTVRAWTSETMSTPLMRTSDPGERP----SLLTRASSSGEMSLPLMRAPASGEIAT 808
             +S+P   + T+E  S P   T+ PG       +  T   S    S  L  +P S  I T
Sbjct: 2254 ALSSPHPSSRTTE--SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITT 2311

Query: 809  --------------------PLRSPAYGAMSAPQMTATASGMMSSMP---QVKAPISGAM 845
                                P+  P+ G          A G +   P   + +A     +
Sbjct: 2312 VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGV 2371

Query: 846  SMPLTRSTASGGMSMPLM--------------------------RAPDSRVTSTSQMMPT 879
             +          +   L+                            P +  TS++ M  +
Sbjct: 2372 PLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSS 2431

Query: 880  ASG------DMCTLPVRAPASGGVSSPLVRAPASGTMSTP-----LRRPSACETVSTELM 928
              G      ++ T      ++G  ++P      +  ++ P     +  P+     ++   
Sbjct: 2432 TPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQ 2491

Query: 929  RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGA- 987
              + + H+ST  TT  V+   + P      +  +P    +A      S   + + + G  
Sbjct: 2492 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 2551

Query: 988  ----------TSTLQTSVANS-----RSMSLSQTTYTVSGRMATAPIRASASG-ARSTSF 1031
                      T+T+ T+  +S      + ++  TT T +G   +    +S  G A +T  
Sbjct: 2552 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKV 2611

Query: 1032 MRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTP------ 1085
            +  + +G    P   +++ G    + +   T T      + +  +S PGT  TP      
Sbjct: 2612 LTTTTTGFTATP---SSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTT 2668

Query: 1086 --QTAFGVMSTPEIKATDSG---EASTSHINITASGSKPTSHMTATTPETAKPP 1134
                A G M+TP      SG     +T+   ITA+GS  T++ ++T   T  PP
Sbjct: 2669 TTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS--TTNPSSTPGTTPIPP 2720



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 168/736 (22%), Positives = 262/736 (35%), Gaps = 90/736 (12%)

Query: 401  PPVRALDSGAMSTP--LMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSAT 458
            PP   L++   +T   L   P   +   L +  PAS   TT++ T+ S G+ S    S  
Sbjct: 1614 PPTTELETATTTTTQALFSTPQPTSSPGLTRAPPAS---TTAVPTL-SEGLTSPRYTSTL 1669

Query: 459  ASRVMSAQLTMA-KTSGAMPTGSMKAVAKQYKRATASGKMST-----PLRRAPTSGAMST 512
             +       T A  T   +P  +   +  +      +G + T     P   APT+ A S 
Sbjct: 1670 GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSR 1729

Query: 513  QPVTATASETMSMPQLT-----VPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQM 567
               T TAS     P  T     + +  S S  +   P +E    P   T  S  T+  Q 
Sbjct: 1730 ARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQP 1789

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTM 627
            K   +        T+  +G          A+G   C   +S+   A + P ++    G +
Sbjct: 1790 KCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQV 1849

Query: 628  FTEKMTT--TASEAMPT------------LLMRDTVSGALSMPQMTDTASGGLSASLMRD 673
             T  + T  T      T            +L  D  S   S P  + TA+    +S    
Sbjct: 1850 LTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTAT---PSSTPGT 1906

Query: 674  TASGAMSTSQMTATVSGGMSMP----LMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPG 729
            T      T+  T T S G +      L  A  P V+  +     V+    S+   +  PG
Sbjct: 1907 TWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTS---SKATPSSSPG 1963

Query: 730  GMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWT---SETMSTPLMRTSDPGERPSLLTR 786
              +  P    TA      S T  + S+     WT     T  T  M T+ P   P     
Sbjct: 1964 TATALPALRSTATTPTATSVTP-IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET--- 2019

Query: 787  ASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMS 846
            A +S  ++       A+G +ATP  +P  G     ++  T +   ++ P   +    A++
Sbjct: 2020 AHTSTVLTATATTTGATGSVATPSSTP--GTAHTTKVPTTTTTGFTATP--SSSPGTALT 2075

Query: 847  MPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPA 906
             P+  ST     + P  R   S VT +S    T +  + T      A+G +++P      
Sbjct: 2076 PPVWISTT----TTPTTRG--STVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129

Query: 907  SGTMSTPLRRPSACETVSTELMRASASGHMST---------AQTTAMVSGGMSKPLMRAP 957
            SGT       PS   T +T     S +   ST           TTA      S  +  + 
Sbjct: 2130 SGT------PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSS 2183

Query: 958  ASGTM---PMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRM 1014
            A GT    P+P   A   G    P        +  T++T+  ++ S  L  TT+      
Sbjct: 2184 ALGTTHTPPVPNTMATTHGRSLPP-------SSPHTVRTAWTSATSGILG-TTHITEPST 2235

Query: 1015 ATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLM 1074
             T+   A+ +G    S    + + S P P  R T S    G + P  T   SR  +T   
Sbjct: 2236 VTSHTLAATTGTTQHS----TPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATP 2291

Query: 1075 RASGPGTM--STPQTA 1088
              +   T+  S+P +A
Sbjct: 2292 SKTRTSTLLPSSPTSA 2307



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 115/577 (19%), Positives = 205/577 (35%), Gaps = 54/577 (9%)

Query: 49   PIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPAS 108
            P+ + S   P  T     TS V  T +       ++   S P      +  L+ L   A+
Sbjct: 4347 PVATMSTIHPSSTPETTHTSTVLTTKATTTRATSST---STPSSTPGTTWILTELTTAAT 4403

Query: 109  DSGALSPLLMPALDSGTLSPL--LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISP 166
             + A  P   P+   GT   L  L+T+     S G    P   +   T  +  + +  + 
Sbjct: 4404 TTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT 4461

Query: 167  LAMPAPSSGVVC-------TPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQ 219
            + +P  S+           TP +ST+++    T     P S   +   +    P + ST 
Sbjct: 4462 VTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATAL----PALRSTA 4517

Query: 220  PVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVAS- 278
              P  +S    P          +S+   T   +  +S+   S T     +S +++A A+ 
Sbjct: 4518 TTPTATSFTAIPSSSLGTTWTRLSQ---TTTPTATMSTATPSSTPETVHTSTVLTATATT 4574

Query: 279  -GGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVM--------STPLLSVPD 329
             G T    T +   G   T  +    +   ++   SSPG+ +         +TP  + P 
Sbjct: 4575 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634

Query: 330  AGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSE-MMSNP 388
                +  P   P     +  L T        T T  A GS A    STQ   +   ++  
Sbjct: 4635 TSGSTVTPSSIPGTTHTARVLTT--------TTTTVATGSMATPSSSTQTSGTPPSLTTT 4686

Query: 389  PVRATASGVMSAP-------PVRALDSGAMSTPLMGAPASGNMSTLQK-------TVPAS 434
                TA+G  + P       P+  + +   +TP   +  + + S+ +        T  A+
Sbjct: 4687 ATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTAT 4746

Query: 435  GAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATAS 494
             +  TS   +PSS + +T  + A  +  MS   T+  +S    T +   +        A+
Sbjct: 4747 KSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRAT 4806

Query: 495  GKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQM 554
               +TP     T+  ++    TAT +             G+  +L   + ++  M     
Sbjct: 4807 NSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGS 4866

Query: 555  RTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTL 591
               AS     A    + +   + P  TA T  S+ST+
Sbjct: 4867 TATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTV 4903



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 150/712 (21%), Positives = 259/712 (36%), Gaps = 87/712 (12%)

Query: 502  RRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGL 561
            R   T+   +T+  TAT + T ++     P S   S    RAP +   ++P   T++ GL
Sbjct: 1607 RGRATTPPPTTELETATTTTTQALFSTPQPTS---SPGLTRAPPASTTAVP---TLSEGL 1660

Query: 562  TS---AAQMKAMTSGAMSTPLMTAQTSG---STSTLLMRDTASGVMSC------PQMRSL 609
            TS    + +   T+G  +TP  + + +    +TSTL  R    G           Q  +L
Sbjct: 1661 TSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTL 1720

Query: 610  ASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSAS 669
            A   ++     P  +GT  T       +   PTL    + S A +    T+T    L+ +
Sbjct: 1721 APTTMATSRARP--TGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNT 1778

Query: 670  LMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPG 729
                  +      + T      +  P        +     +RA   GKM   P S +   
Sbjct: 1779 TTSQGTTRCQPKCEWTEWFD--VDFPTSGVAGGDMETFENIRA-AGGKMCWAPKSIECRA 1835

Query: 730  GMSMSPMKSMTAGGMQMNSPTSDVMSTP----TVRAWTSETMSTPLMRTSDPGERPSLLT 785
                 P  S+   G  +       ++      T R       +  ++   D    PS   
Sbjct: 1836 --ENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPA 1893

Query: 786  RASSSGEMSLP----LMRAPASGEIATP----LRSPAYGAMSAPQ-----MTATASGMMS 832
             +S++   S P    ++  P +    T       +P     +AP       TAT   + S
Sbjct: 1894 TSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTS 1953

Query: 833  SMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST-----SQMMPTASGDMCT- 886
            S     +    A ++P  RSTA+   +  +   P S + +T         PTA+    T 
Sbjct: 1954 SKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013

Query: 887  --LPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE-----TVSTELMRASASGHMSTA 939
               P  A  S  +++      A+G+++TP   P         T +T    A+ S    TA
Sbjct: 2014 SSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 2073

Query: 940  QTTAMVSGGMSKPLMR----APAS-------GTMPMPLMSAMASGEMSMPLMETMASGAT 988
             T  +     + P  R     P+S        T+     + +A+G M+ P   T  SG  
Sbjct: 2074 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTP 2133

Query: 989  STLQTSVANSRSMSLSQTTYTVSGRMATAPI------RASASGARSTSFMRASVSGSM-- 1040
             +L T+   + +++ + +T   S    T PI       A+   A S +   +S  G+   
Sbjct: 2134 PSLTTT---ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHT 2190

Query: 1041 -PMPLPRATASGCGMGMSMPQMTATDSRGMSTPLM---RASGPGTMST----PQTAFGVM 1092
             P+P   AT  G  +  S P    T     ++ ++     + P T+++      T     
Sbjct: 2191 PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQH 2250

Query: 1093 STPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGML 1144
            STP + +      +T   +  + G+    H TAT+  TA   P +  +  +L
Sbjct: 2251 STPALSSPHPSSRTTE--SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLL 2300


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score =  105 bits (261), Expect = 4e-22
 Identities = 251/1170 (21%), Positives = 452/1170 (38%), Gaps = 181/1170 (15%)

Query: 48    LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPAS---DSGALSPLL 104
             +P  + S   PG  ++ + +S    + + P++        + P M  S   ++G+  P +
Sbjct: 10921 IPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTV 10980

Query: 105   MP---------ASDSGALSPLLMPALDSGT----LSPLLSTSEYGVMSPGMMTI-PDFGT 150
             +P          + S A++   +P L         +P ++TS     S  + T+ P+   
Sbjct: 10981 LPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPG 11040

Query: 151   MSATLMVAPDSAEISPLAMPAPSSGVV-CTPIMSTS----SSEAMSTPLMLAPDSGELSP 205
             +  +L+ +      + +     S G +  TP M+TS    +S A+ TP +    SG ++P
Sbjct: 11041 VVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTP 11100

Query: 206   ILMQDMNPGVMSTQPVPAPSSEA--MSPLQITDEDTEAMSKVL-MTALASGEISSLLMSG 262
              L+        +T P+   SS     +P   T    EA S VL ++    G ++SL+   
Sbjct: 11101 -LVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLV--- 11156

Query: 263   TDSEAISSLIMSAVASGGTSPQPTST-------QNSGGIPTPLMSDLDSGIMSSLLMSSP 315
             T S A++S  +  +      P+ T++       +    IPT  +S    G+++SL+ SS 
Sbjct: 11157 TSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSS- 11215

Query: 316   GSEVMSTPLLSVPDAGEM---STLPKPAPDAEAMSPALM--TALPSGVMPTQTMPAPGSG 370
             GSE  +   L+V  +      S +  P  +A ++ P L   T  P   +   T PA  S 
Sbjct: 11216 GSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSS 11275

Query: 371   AMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKT 430
              +   +++   SE+ + P         +++P   A  S A+ST +    + G    L   
Sbjct: 11276 TLPRTTSRFSHSELDTMP-------STVTSP--EAESSSAISTTI----SPGIPGVLTSL 11322

Query: 431   VPASGA-MTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYK 489
             V +SG  ++ +  TVP S      +  ATAS V    +T        P  S         
Sbjct: 11323 VTSSGRDISATFPTVPES----PHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPS 11378

Query: 490   RATASGKMSTP----LRRAPTSGAMSTQPVTATASET-MSMPQLTVPASGSMSMLQMRAP 544
              AT+ G  +T     +  +P    M T  VT++ ++T +++P LT+ +SG          
Sbjct: 11379 IATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTL-SSGEPETTTSFIT 11437

Query: 545   VSEAMSMPQMRTM--ASGLTSAAQMKAMTSGAMSTPLMTAQTS---------------GS 587
              SE  +   + T+  + G +       ++SG  ST      T                  
Sbjct: 11438 YSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAE 11497

Query: 588   TSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRD 647
             T+T++ R T     S  +  +    A++ P   P+AS  + T  ++   S+ + +L+   
Sbjct: 11498 TNTMVPRTTPK--FSHSKSDTTLPVAITSP--GPEASSAVSTTTISPDMSDLVTSLVPSS 11553

Query: 648   TVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD------ 701
                 + + P +++T            TA+     ++ + TVSG +     R  D      
Sbjct: 11554 GTDTSTTFPTLSETPYEP------ETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMV 11607

Query: 702   --PGV-----MPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVM 754
               PGV     +P + +   + G + SQ  S+      + + + ++T    +  +  S   
Sbjct: 11608 TSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATD---TSTAIPTLTPSPGEPETTASSAT 11664

Query: 755   STPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPA 814
                T   +T    + P   +S+P    S +T    +   S P+ R  +S   ++P  +P 
Sbjct: 11665 HPGTQTGFTVPIRTVP---SSEPDTMASWVTHPPQT---STPVSRTTSSFSHSSPDATPV 11718

Query: 815   YGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS 874
                 ++P+  A+++ + +  P       GA  M  ++ T+SG               +TS
Sbjct: 11719 MA--TSPRTEASSAVLTTISP-------GAPEMVTSQITSSGA--------------ATS 11755

Query: 875   QMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASG 934
               +PT      T     P +  + S   R   S T       P   ET ++  +R  A  
Sbjct: 11756 TTVPTL-----THSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAE- 11809

Query: 935   HMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTS 994
               STA  T   S      L     +GT  + L    + G           S  T+ L T 
Sbjct: 11810 -TSTALPTQTTSS-----LFTLLVTGTSRVDLSPTASPG----------VSAKTAPLSTH 11853

Query: 995   VANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGM 1054
                  S  +  +T ++     T  +  S+S   STS +  +VS ++      +  S   +
Sbjct: 11854 PGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAV------SGLSSASI 11907

Query: 1055  GMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGV------MSTPEIKATDSGEASTS 1108
                 PQ T T     ++P + + GP   S   T   +      M TP   +   G + T+
Sbjct: 11908 TTDKPQ-TVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTT 11966

Query: 1109  HI--------NITASGSKPTSHMTATTPET 1130
              +        N+  +GS PT   T TT  T
Sbjct: 11967 ILRTTMVEATNLATTGSSPTVAKTTTTFNT 11996



 Score =  100 bits (248), Expect = 1e-20
 Identities = 276/1208 (22%), Positives = 470/1208 (38%), Gaps = 190/1208 (15%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMG------------VPNSGALSPPL---- 91
            LP+ S   S P  T+  L TSP   T S P +               N+ A+ P      
Sbjct: 7124 LPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAA 7183

Query: 92   ----MPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPL-----LSTSEYGVMSPGM 142
                +P+S   + S  L  +  S A SP+ + +    T   +     L TS     S   
Sbjct: 7184 SNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISS 7243

Query: 143  MT--IPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTS----SSEAMSTPLML 196
            ++  + + G+   T      SA +S +++ A ++ +  T + S+S    S  A ST L  
Sbjct: 7244 LSPKLRETGSSVETSSAIETSAVLSEVSIGA-TTEISRTEVTSSSRTSISGSAESTMLPE 7302

Query: 197  APDSGEL-----SPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMT-AL 250
               + ++     SPIL +     + +    P  +SE+   L  +   +  ++   MT  L
Sbjct: 7303 ISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRL 7362

Query: 251  ASGEISSLLMSGT-DSEAISSLIMSAVASGGTSPQPTSTQNSGGI-PTPLMSDLDSGIMS 308
               EI++L+  G  D    SSL +       TSP  +    S  I P+P+ S L +   S
Sbjct: 7363 PHSEITTLVSRGAGDVPRPSSLPVEE-----TSPPSSQLSLSAMISPSPVSSTLPASSHS 7417

Query: 309  S----LLMSSPGSEVMSTPLLSVPDAGEMSTLPK-PAPDAEAMSPALMTALPSGVMP--- 360
            S      + +PG +V +T +L      E S+ P   +   E ++ + +T     + P   
Sbjct: 7418 SSASVTSLLTPG-QVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSN 7476

Query: 361  --TQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMST-PLMG 417
                 +    SG  SP S+   DSE         T S +M    V  L     +T  +  
Sbjct: 7477 TAVTKVGTSSSGHESP-SSVLPDSETTKATSAMGTIS-IMGDTSVSTLTPALSNTRKIQS 7534

Query: 418  APASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMP 477
             PAS   + L++T   S +  TSL T  ++ V+S     AT     +  ++ ++TS + P
Sbjct: 7535 EPASSLTTRLRET---STSEETSLAT-EANTVLSKVSTGATTEVSRTEAISFSRTSMSGP 7590

Query: 478  ---TGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASG 534
               T S         R +AS  ++   +   T+    T P  +T   T+++   T P   
Sbjct: 7591 EQSTMSQDISIGTIPRISASSVLTESAKMTITT---QTGPSESTLESTLNLNTATTP--- 7644

Query: 535  SMSMLQMRAPVSEAMSMPQMRTM----ASGLTSAAQMKAMTSGAMSTPL-MTAQTS-GST 588
              S ++  + V +    P+M T       G++  +      +   S+PL + A TS    
Sbjct: 7645 --SWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPV 7702

Query: 589  STLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDT 648
            ST  +       +    + +      +  L T    GT  +  ++TT+ E + T   +DT
Sbjct: 7703 STTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTT--YKDT 7760

Query: 649  VSGALSMP-------QMTDTASGGLS-ASLMRD-----TASGAMSTSQMTAT----VSGG 691
                   P        +  T+SG  S +S++ D     T S    TS +T+T     +  
Sbjct: 7761 AHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRR 7820

Query: 692  MSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTS 751
            +   L  +  PG+  +S      SG  +S  +S    G  +    + +T+      S  S
Sbjct: 7821 IQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTIS 7880

Query: 752  DVMSTPTVRAW-------------TSETMSTPLMRTS------DPGERPSL------LTR 786
              +ST TV +W             T  T ++PL  T+      D     SL      +++
Sbjct: 7881 PDISTRTV-SWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQ 7939

Query: 787  ASSSGEMSLPLMRAPASGEIATP----LRSPAYGAMSAPQMTATASGMMSSMPQVKAPIS 842
              S  +MS  + R P      +P       P++  MS+P  T + S + S++P+    IS
Sbjct: 7940 GFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSP-ATTSPSPVSSTLPE---SIS 7995

Query: 843  GAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLV 902
             +  +P+T    SG             +  T+ M+  +S  +      +PA+   +S  +
Sbjct: 7996 SS-PLPVTSLLTSG-------------LAKTTDMLHKSSEPV----TNSPANLSSTSVEI 8037

Query: 903  RAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTM 962
             A +  T  T    PS+  TV+   +  S+SGH ST  +  +     SK         T 
Sbjct: 8038 LATSEVTTDTEKTHPSSNRTVTD--VGTSSSGHEST--SFVLADSQTSKV--------TS 8085

Query: 963  PMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMAT------ 1016
            PM + S M    +S     T     TS +QT   +S ++ L +T+ +    +AT      
Sbjct: 8086 PMVITSTMEDTSVS---TSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVL 8142

Query: 1017 --APIRASASGARS--TSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTP 1072
               P  A+A  +R+  TS  R S+SG   + +   T+            T T +R  ++ 
Sbjct: 8143 SGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETS------------TETITRLPTSS 8190

Query: 1073 LMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAK 1132
            +M  S    + T     G  STPE   T     + + +   ++ ++  SH   TT  +  
Sbjct: 8191 IMTESAEMMIKTQTDPPG--STPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRS 8248

Query: 1133 PPPKEVPS 1140
            P     PS
Sbjct: 8249 PGDMLWPS 8256



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 254/1131 (22%), Positives = 417/1131 (36%), Gaps = 144/1131 (12%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMP 106
            +LP  S+S+SD   TS    T  V  T S     +    A S P + +SD        +P
Sbjct: 2362 ELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQ-----VP 2416

Query: 107  ASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISP 166
             S +   +    P++ S T S    ++  G  S    T+P F   + T  V   SA ++ 
Sbjct: 2417 TSTT-ETNTATSPSVSSNTYSLDGGSNVGGTPS----TLPPF---TITHPVETSSALLAW 2468

Query: 167  LAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPA--- 223
                   S +V T   S  +  + ++ +   P  G  +          V ST  +PA   
Sbjct: 2469 SRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWT---------SVGSTTDLPAMGF 2519

Query: 224  ----PSSEAMSPLQITDEDTEAMSKVLMTALASGEIS---SLLMSGTDSEAISSLIMSAV 276
                P+ EA S L  T E   A +  L  A+ +G  +   + L++ ++S+AI S      
Sbjct: 2520 LKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHS------ 2573

Query: 277  ASGGTSPQPTSTQNSGGIPTP-----LMSDLDSGIMSSLLMSSP-GSEVMSTPLLSVPDA 330
             S  T   PTS  N     TP     +    D+ + S +L++       +STP    P  
Sbjct: 2574 -SPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPST 2632

Query: 331  GEMS--TLPKPAPDAEAM-----SPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSE 383
            G +S  + P   PD  A+      P    A      P  T+ +   G + P +T  +   
Sbjct: 2633 GTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTV-PETTLTMSET 2691

Query: 384  MMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMT 443
               +  V  T S    + P   +  G   +PL  +  S +     +     G++T +L T
Sbjct: 2692 SNGDALVLKTVSNPDRSIPGITI-QGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALST 2750

Query: 444  VPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRR 503
            +P+    +T  +  + S   S    +  +S  +   S+  +    +   +SG + +    
Sbjct: 2751 LPAG---TTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTH 2807

Query: 504  APTSGAMSTQPVTATASETMSMPQLTV-PASGSMSMLQMRAPVSEAMSMPQMRTMASGLT 562
            +  +   S+ P+T    E  +M ++T    + + S      PV    +   + T  S   
Sbjct: 2808 STGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVS--A 2865

Query: 563  SAAQMKAMTSGAMSTPLMTAQTSGST---STLLMRDTASGVMSCPQM---------RSLA 610
            S++  KA  S   + P      S  T   S +   DT S  +  P            S A
Sbjct: 2866 SSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTA 2925

Query: 611  SGALSK-PLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSAS 669
            S +LSK P   P+A   M T     +AS    T                T+T  G  S S
Sbjct: 2926 SSSLSKSPEKNPRA--RMMTSTKAISASSFQST--------------GFTETPEGSASPS 2969

Query: 670  LMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDP- 728
            +         S +      S  MS P     DP    +++    ++ K+ +   + Q   
Sbjct: 2970 MAGHEPRVPTSGTGDPRYASESMSYP-----DPSKASSAMTSTSLASKLTTLFSTGQAAR 3024

Query: 729  GGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRAS 788
             G S SP+   T       SPT+            S +  T L        +P++L    
Sbjct: 3025 SGSSSSPISLSTEKETSFLSPTA------------STSRKTSLFLGPSMARQPNILVHLQ 3072

Query: 789  SSGEMSLPLMRAPASGEIATPLRS-----PAYGAMSAPQ-MTATASGMMSSMPQVKAPIS 842
            +S     P      S E    L S        G  +  Q +T T S   +S+  V +P  
Sbjct: 3073 TSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTE 3132

Query: 843  GAMSMPLTRSTASGGMSMP----LMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVS 898
                   +  T +  +S+P    L+   D  + +T +M   A+    T P  APA    S
Sbjct: 3133 PTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWP--APAEETGS 3190

Query: 899  SPLVRAPASGTMSTPLRRPSACE-TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAP 957
            SP   +P S  MST L+  S+ E ++S E+     +    T +TT              P
Sbjct: 3191 SPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETT-------------VP 3237

Query: 958  ASGTM-PMPLMS-AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQT-----TYTV 1010
               T+ P+ L S A+ SG  S+  + T  +  T +   ++  +  +SLS +     T   
Sbjct: 3238 METTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLY 3297

Query: 1011 SGRM-ATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGM 1069
            SG    T    A+ S     S    S++G+     P   +   GM  SM   +   + G 
Sbjct: 3298 SGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTG- 3356

Query: 1070 STPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGE--ASTSHINITASGSK 1118
             T +  ++    +  P T+   +S+   K+    E   ST+ I  T   +K
Sbjct: 3357 DTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNK 3407



 Score = 97.8 bits (242), Expect = 6e-20
 Identities = 249/1212 (20%), Positives = 449/1212 (37%), Gaps = 188/1212 (15%)

Query: 58   PGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSG-ALSPLLMPASDSGALSPL 116
            P G +T++  + V  +    + G P+   +SP +   + +  + SP++  +++S      
Sbjct: 8441 PSGATTEVSRTEVISSRGTSMSG-PDQFTISPDISTEAITRLSTSPIMTESAESAITIET 8499

Query: 117  LMP-ALDSGTLSPLLSTSEY-----GVMSPGMMTIPDFGTMSAT-----LMVAPDSAEIS 165
              P A   GTL+   ST+ +        SPG         MS T         P   E S
Sbjct: 8500 GSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEAS 8559

Query: 166  PLAMPAPSSGVVCTPIMSTSSSEAMSTP----LMLAPDSGELSPILMQDMNPGVMSTQPV 221
             ++    S  +  T   ST      S+P     +L     + + +L     P   S   +
Sbjct: 8560 SVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNL 8619

Query: 222  PAPSSEAMSPLQITD--EDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASG 279
             + S+E ++  ++T   E     S   +  + +     L  S   ++ +++   S +A+ 
Sbjct: 8620 SSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATT 8679

Query: 280  GTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMS---------------TPL 324
             T    + + ++   P  +M+   S + S L   S   E  S               T  
Sbjct: 8680 STLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTK 8739

Query: 325  LSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTM---------PAPGSGAMSPW 375
            +S  +A  +     P P    +SP + T   + +    T          P  G    S  
Sbjct: 8740 VSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQ 8799

Query: 376  STQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPAS---GNMSTLQKTVP 432
             T  +D+        RA+  G  SA   R+  SG M+TP+   P      +  +++KT P
Sbjct: 8800 GTFTLDTSS------RASWPGTHSAATHRSPHSG-MTTPMSRGPEDVSWPSRPSVEKTSP 8852

Query: 433  ASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL---TMAKTSGAMPTG---------- 479
             S  ++ S +T PS  + ST   S+ +S +    L    M KT+  + T           
Sbjct: 8853 PSSLVSLSAVTSPSP-LYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPS 8911

Query: 480  --------------SMKAVAKQYKRATASGKMSTPLRR----APTSGAMSTQPVTA---T 518
                          +M+  A Q    TA  +M T   R    +   G      VT+   T
Sbjct: 8912 MNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVT 8971

Query: 519  ASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTP 578
            +S    +   T+PAS  ++ ++M +  S     P+  + +  + SA +         ST 
Sbjct: 8972 SSTIKDIVSTTIPASSEITRIEMES-TSTLTPTPRETSTSQEIHSATKP--------STV 9022

Query: 579  LMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTE--KMTTTA 636
               A TS +    + +  +S     P  +S  S  +S  ++T  ++  + TE  +MT T 
Sbjct: 9023 PYKALTSATIEDSMTQVMSSSRGPSPD-QSTMSQDISTEVITRLSTSPIKTESTEMTITT 9081

Query: 637  SEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSG------ 690
                P    R T++   S   M+ T S          TAS   S SQMTA +S       
Sbjct: 9082 QTGSPGATSRGTLTLDTSTTFMSGTHS----------TASQGFSHSQMTALMSRTPGDVP 9131

Query: 691  ---------------GMSMPLMRAQDP--GVMPASLMRAK--VSGKMLSQPMSTQDPGGM 731
                            +S P+M +  P    +P S+  +   V+  + S  + T +  G 
Sbjct: 9132 WLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGT 9191

Query: 732  SMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPS------LLT 785
            S  P    T+    ++S ++++++   V   T +   T ++ +    E PS      + T
Sbjct: 9192 SSEPE---TSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTT 9248

Query: 786  RASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATAS---GMMSSMPQVKAPIS 842
            +A+SS  ++ P      +G+      +PA+   S  Q  +  S   G+M +   +    S
Sbjct: 9249 KATSSMGITYP------TGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMET--SISEETS 9300

Query: 843  GAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLV 902
             A       S+   G +  + R     ++S+   +P  +    +          +S+PL 
Sbjct: 9301 SATEKSTVLSSVPTGATTEVSRT--EAISSSRTSIPGPAQSTMSSDTSMETITRISTPLT 9358

Query: 903  RAPASGTMSTPLRRPSACETVSTELMRASASGH---MSTAQTTAMVSGGMSKPLMRAPAS 959
            R  ++    TP   PS   +  T  + +S++       +A T       ++ P+ R P  
Sbjct: 9359 RKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPED 9418

Query: 960  GTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTY-TVSGRMATAP 1018
             + P PL     S E + P              +S+ +S S++     Y T SG   ++P
Sbjct: 9419 VSWPSPL-----SVEKNSP-------------PSSLVSSSSVTSPSPLYSTPSGSSHSSP 9460

Query: 1019 IRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASG 1078
            +  +   +  TS M    +  +   L   T S   M ++  +  A       T  +    
Sbjct: 9461 VPVT---SLFTSIM-MKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFE 9516

Query: 1079 PGTMSTPQTAFGVMSTPEIKATDSG-EASTSHINITASGSKPTSHMTATT-PETAKPPPK 1136
                S  +T     +T E+ ++  G    T  I+   + S    +M +TT P ++     
Sbjct: 9517 NTAASHVET---TSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRI 9573

Query: 1137 EVPSFGMLTPAL 1148
            E+ S   LTP L
Sbjct: 9574 EIESMSSLTPGL 9585



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 269/1217 (22%), Positives = 444/1217 (36%), Gaps = 184/1217 (15%)

Query: 84   SGALSPPLMPASDSGALSPLLMPASDSGAL----SPLLMPALDSGTLSPLLSTSEYGVMS 139
            +G+ S    P  DSG     L P + +GA+      L   + D    SP  S       S
Sbjct: 19   TGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLASPTSSVVGRTTQS 78

Query: 140  PGMMT--IPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSS---------- 187
             G+M+  +P+  +   T      S  +SP     PS     T ++S  SS          
Sbjct: 79   LGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEG 138

Query: 188  ----EAMSTPLMLAPDSGEL---------SPILMQDMNPGVMSTQPVP------------ 222
                EA +  L +   SG +         +     D       T+ +P            
Sbjct: 139  NFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFAD 198

Query: 223  -------APSSEAMSPLQITDEDTEAMSKVLMTALASG--EISSLLMSGTDSEAISSLIM 273
                   AP S   +   +TD  T   +      L S   ++S      +  E    LI+
Sbjct: 199  STASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELIL 258

Query: 274  SAVASGGTSPQPTSTQNSG-GIPTPLMSD---LDSGIMSSLLMSSPGSEVMSTPLLSVPD 329
            S      +SP+P S  +S      PL S    LD+ I  + + S  G  + S     VP+
Sbjct: 259  STTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFS--GQSLTSPLSPGVPE 316

Query: 330  AGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQ------NVDSE 383
            A   ST+P     A   S  L  A  S      T+ + G+ ++S   T       +  +E
Sbjct: 317  A-RASTMPN---SAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAE 372

Query: 384  MMSNPPVRAT---------ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPAS 434
             M  P              + G +      AL + + ST L+    + + ST  K     
Sbjct: 373  TMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGK--ETE 430

Query: 435  GAMTTSLMTVPSSGVMSTEQMSATA------SRVMSAQLTMAKTSGAMPTGSMKAVAKQY 488
            G + TS+  + +S      +M+AT       + + S   + ++ S + PT  ++      
Sbjct: 431  GTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTS 490

Query: 489  KR---ATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPV 545
             R   +TA+   S  LR   +S + ++   + + ++  S PQ T     S SM   R P 
Sbjct: 491  GRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPA 550

Query: 546  SEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSG------STSTLLMRDTASG 599
            S +++ P   ++ S          + SG   T L T+ T G      S  TL+   TA  
Sbjct: 551  STSVAAPITTSVPS----------VVSG--FTTLKTSSTKGIWLEETSADTLIGESTAGP 598

Query: 600  V---MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMP 656
                 + P   S+  G+ ++         T  T    T+A   + T  +  +VS A+S  
Sbjct: 599  TTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKT 658

Query: 657  QMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPL--MRAQDPGVMP----ASLM 710
                +  GG   S    ++    ++S  ++    G S+ L  +  + P   P    A   
Sbjct: 659  AAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHT 718

Query: 711  RAKVSGKMLSQPMSTQDPGGMSMS-----PMKSMTAGGMQMNS---PTSDVMSTPTV-RA 761
            +   S  +LS     +D    + +        S+T G  ++++   P+S V+S+ T+  A
Sbjct: 719  KISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNA 778

Query: 762  WTS----ETMSTPLMRTSDPGERP--SLLTRASSSGEMSLPLMRAPASGEIATPLRSPAY 815
             TS       ++PL   S  GE    S+LT ++S+     P +    +    T   S + 
Sbjct: 779  ATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGT---LTSESSESP 835

Query: 816  GAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQ 875
              +S P ++   +   SS P      SG      T  T++  +S P       R T  S 
Sbjct: 836  STLSLPSVSGVKTTFSSSTPSTHLFTSGEE----TEETSNPSVSQPETSVSRVRTTLAST 891

Query: 876  MMPT-ASGDMCTLPVRA---PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMR-- 929
             +PT     M T P R+    +S  VS     +  S T ST    P       T  M   
Sbjct: 892  SVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQT 951

Query: 930  -------ASASGHMSTAQTTAMVSGGMSKPLMRAPASGT--MPMPLMSAMASGEMSMPLM 980
                   ++A    +  +T+     G+         S T      ++S   S   S    
Sbjct: 952  NRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEA 1011

Query: 981  ETMASGATSTLQTSVANS-RSMSLSQTT------YTVSGRMATA--PIRASASGARSTSF 1031
             ++   +T+ L T   N   SM+++ T       Y   GR+ T+  PI  +AS   S  F
Sbjct: 1012 TSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDF 1071

Query: 1032 MRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGV 1091
              A  S SM +     + S    G S P  T+      S  +   +    ++ P+     
Sbjct: 1072 TMAKESVSMSV---SPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTS-REITIPRDGTSS 1127

Query: 1092 MSTPEIKAT-----DSGEASTSHINI-TASGSKPTSHMTAT---------------TPET 1130
              TP++ AT     D G A ++ + I ++S S PT  +T +               T ET
Sbjct: 1128 ALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVET 1187

Query: 1131 AKPPPKEVPSFGMLTPA 1147
            ++     +PS   LTP+
Sbjct: 1188 SRWNMPNLPSTTSLTPS 1204



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 255/1222 (20%), Positives = 428/1222 (35%), Gaps = 178/1222 (14%)

Query: 33   TETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLM 92
            +ET  D  +    V + +  + + D  G+ST   TS   DT S  +  + +     P   
Sbjct: 1065 SETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIP--- 1121

Query: 93   PASDSGALSPLLM----PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF 148
                S AL+P +     P+ D G+     +  L S   SP          +P +     F
Sbjct: 1122 RDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSP----------TPKVTMSSTF 1171

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPI-MSTSSSEAMSTPLMLAPDSGELSPIL 207
             T   T  +  D+ E S   MP   S    TP  + TS +   ST + L   S   S   
Sbjct: 1172 STQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEA 1231

Query: 208  MQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEA 267
             +   P  +ST P    +         + E    +   + + +  G  + L     ++  
Sbjct: 1232 SEGGLP-TLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHI 1290

Query: 268  ISSLIMSAVASGG----TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTP 323
              S    A +SG     T+P  T+T  S   PT  ++  D    SS  +S+P S      
Sbjct: 1291 HVSTARMAYSSGSSPEMTAPGETNT-GSTWDPTTYITTTDPKDTSSAQVSTPHS------ 1343

Query: 324  LLSVPDAGEMSTL--PKPAPDAEAMSPALMTALPS-GVMPTQTMPAPGSGAMSPWSTQNV 380
                     + TL   +  P  E+ +PA  +  P     P  T PA  +  ++  +T++ 
Sbjct: 1344 ---------VRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITD-TTEHS 1393

Query: 381  DSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTS 440
                 +    +++     SAP       G +S  +  +P  G+ STL+ T    G     
Sbjct: 1394 TQLHYTKLAEKSSGFETQSAP-------GPVSVVIPTSPTIGS-STLELTSDVPG---EP 1442

Query: 441  LMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTP 500
            L+  PS     T  M+   S  ++ ++       + P+  M   A     +T S ++S  
Sbjct: 1443 LVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKS 1502

Query: 501  --------------------LRRAPTSGAMSTQPVTA-----------------TASETM 523
                                +R    +G ++T P+T                  T S TM
Sbjct: 1503 EADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATM 1562

Query: 524  S--------MPQLTVPASGSMSMLQMRAPV--SEAMSMPQMRTM--ASGLTSAAQMKAMT 571
            S          Q ++PAS S S L    P   ++  S  +  T    S  T + +++   
Sbjct: 1563 SPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGP 1622

Query: 572  SGAMSTPLMTAQTSGSTSTLLMRDTA------------SGVMSCPQMRSLA--SGALSKP 617
            +   STP M   T+GS+S+ +    A            S  M+  +  S A  S A +  
Sbjct: 1623 TNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMG 1682

Query: 618  LMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASG 677
            L+   A G   ++ +   +S    +     T S   S P++    +  LS+SL    A G
Sbjct: 1683 LLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEG 1742

Query: 678  AMSTSQMTATVS---------GGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDP 728
            +  ++ +  T S         GG +      +   VM + + ++    +  S  + +   
Sbjct: 1743 SQMSTSIPLTSSPTTPDVEFIGGST--FWTKEVTTVMTSDISKSSARTESSSATLMSTAL 1800

Query: 729  GGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRAS 788
            G    +  + +    M + SPT  +  TP +    S   +T        G   S     +
Sbjct: 1801 GSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLA 1860

Query: 789  SSGEMSLPLMRAP-ASGEIATPLRSPAYGAMSAPQMTATASGMMSS----MPQVKAPISG 843
            +   ++  + RA        T  +S + G  +   MT T    +SS     P+  AP   
Sbjct: 1861 TDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAP-GA 1919

Query: 844  AMSMPLTRSTASGGMSMPLMRAPDSRVTST---------------SQMMP-------TAS 881
              ++  T    +  +++P    P   V ST               S + P       T +
Sbjct: 1920 ETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGT 1979

Query: 882  GDMCTLPVRAPASGGV-----SSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHM 936
             +  T P+ A +S  V     S+P V + A     T     S+  + S+    AS     
Sbjct: 1980 IEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLD 2039

Query: 937  STAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGE--MSMPLMETMASGATSTLQTS 994
            ST      ++  +       P +      L  A++SG   +S P   T      S   TS
Sbjct: 2040 STISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTS 2099

Query: 995  VANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGM 1054
             A  R+    +T        A + +   AS     S      S S  +PLP A  S   +
Sbjct: 2100 AAKQRN---PETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDV 2156

Query: 1055 GMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITA 1114
                 + TA  S G       AS  GT  T       +S P  ++  S   +     ++ 
Sbjct: 2157 SGLTSESTANPSLG------TASSAGTKLT-----RTISLPTSESLVSFRMNKDPWTVSI 2205

Query: 1115 S-GSKPTSHMTATTPETAKPPP 1135
              GS PT++   + P  +  PP
Sbjct: 2206 PLGSHPTTNTETSIPVNSAGPP 2227



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 258/1239 (20%), Positives = 437/1239 (35%), Gaps = 203/1239 (16%)

Query: 33   TETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLM 92
            +ET AD+ +  + V + +    +    G+S    T P +  +S+    +P + +L     
Sbjct: 634  SETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSV---IPETSSLQSSAF 690

Query: 93   PASDSGALSPLLMPASDSGALSPLLMPALDSG------TLSPLLSTSEYGVMSPGMMTIP 146
                S  L+PL           P   P  DS       T  PLLS++   V+   +    
Sbjct: 691  REGTSLGLTPL-------NTRHPFSSPEPDSAGHTKISTSIPLLSSAS--VLEDKVSATS 741

Query: 147  DFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA-----MSTPLMLAPDSG 201
             F    AT  +   + EIS      PSS V+ +  +S +++        ++PL     SG
Sbjct: 742  TFSHHKATSSITTGTPEIS--TKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSG 799

Query: 202  E--------LSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASG 253
            E        LS       +P +  T  + + SSE+ S L +      ++S V  T  +S 
Sbjct: 800  EETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLP-----SVSGVKTTFSSST 854

Query: 254  EISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMS 313
              + L  SG ++E  S+  +S   +  +  + T    S  +PTP+   +D+    S   S
Sbjct: 855  PSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTS--VPTPVFPTMDTWPTRSAQFS 912

Query: 314  SPG--SEVMSTPLLSVPDAGEMSTLPKPA--PDAEAMSPALM-----TALPSGVMPTQTM 364
            S    SE+ +T   SV ++   S LPK +       MS         +A P      +T 
Sbjct: 913  SSHLVSELRATSSTSVTNSTG-SALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETS 971

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPV----RATASGVMSAPPVRALDSGAMSTPLMGAPA 420
            P   +G  S  +T +  +  +S   +     + A+  M A  +R   +  ++T     P 
Sbjct: 972  PRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGP- 1030

Query: 421  SGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQM--SATASRVMSAQLTMAKTSGAM-- 476
             G+M+     +P      T        G + T  +    TAS   S   TMAK S +M  
Sbjct: 1031 -GSMAVASTNIPIGKGYITE-------GRLDTSHLPIGTTASSETSMDFTMAKESVSMSV 1082

Query: 477  -PTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS 535
             P+ SM A              STP R +      S      T+ E      +T+P  G+
Sbjct: 1083 SPSQSMDAAGS-----------STPGRTSQFVDTFSDDVYHLTSRE------ITIPRDGT 1125

Query: 536  MSML--QMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLM 593
             S L  QM A    +      R+   G+ S++         MS+   T + + S     +
Sbjct: 1126 SSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTV 1185

Query: 594  RDTASGVMSCPQMRSLA------SGALSKPLMTPKASGTMFTEKMTTTASEA-MPTLLMR 646
              +   + + P   SL       SGA+ K  + P  + +  T   +  ASE  +PTL   
Sbjct: 1186 ETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPAT---SLEASEGGLPTLS-- 1240

Query: 647  DTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLM--------- 697
                   + P+ T+T S  L A    ++ S    T  M + V  G   PL          
Sbjct: 1241 -------TYPESTNTPSIHLGAHASSESPSTIKLT--MASVVKPGSYTPLTFPSIETHIH 1291

Query: 698  -------------------------RAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMS 732
                                        DP     +      S   +S P S +      
Sbjct: 1292 VSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTE 1351

Query: 733  MSPMKSMTAGGMQMNSP---TSDVMSTPTVRAWT--SETMSTPLMRTSDPGERPSLLTRA 787
              P            SP   +S  +++P  +AWT    T  +  +  +   E+ S     
Sbjct: 1352 NHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQ 1411

Query: 788  SSSGEMSLPLMRAPASGEIATPLRSPAYG-----------AMSAPQMTATASGMMSSMPQ 836
            S+ G +S+ +  +P  G     L S   G            ++ P  T  ++ +   M  
Sbjct: 1412 SAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMAS 1471

Query: 837  VKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTAS--------------- 881
                IS   S P++       MS P      S    TS +  T S               
Sbjct: 1472 TDLDISSPSS-PMSTFAIFPPMSTPSHELSKSEA-DTSAIRNTDSTTLDQHLGIRSLGRT 1529

Query: 882  GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVS--TELMRASASGHMSTA 939
            GD+ T+P+    +   S       A  T+S  +      +++   T +  +++  H++  
Sbjct: 1530 GDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEV 1589

Query: 940  QTTAMVSGGMSKPLMR--APASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVAN 997
                   G  S        P++ T+   + +   + + + P+  T    ++S +   +A+
Sbjct: 1590 YPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAH 1649

Query: 998  -----------SRSMSLSQTTYTVSGRMA--------TAPIRA-SASGARSTSFMRAS-- 1035
                       S +M+L + + T +  MA        +AP R+ S S  R +S +  S  
Sbjct: 1650 LPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTT 1709

Query: 1036 --VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMS 1093
              V+ S     PR    G     S  + +  +   MST +   S P T            
Sbjct: 1710 EGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFW 1769

Query: 1094 TPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAK 1132
            T E+    + + S S     +S +   S    +T  T K
Sbjct: 1770 TKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGK 1808



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 284/1212 (23%), Positives = 445/1212 (36%), Gaps = 262/1212 (21%)

Query: 143  MTIPDFGTMSATLMVAPDS----AEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAP 198
            MT  +   +S+++   P++    AE +  + P   +  +  P  S    E +ST +   P
Sbjct: 1896 MTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGP 1955

Query: 199  DSGELSPILMQDMNPGVM----------STQPVPAPSSEAMSPLQITDEDTEAMSKVLMT 248
            D    +P+    + P  +          STQP+ A SSE +S   +  + T  ++ V ++
Sbjct: 1956 DINS-APMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVS---VQTQSTPYVNSVAVS 2011

Query: 249  A-------LASGEISSLLMSGTDSEAISSLIM--SAVAS---GGTSPQPTSTQNSGGIPT 296
            A       ++SG  +S   S    E++ S I   +A+ S     T+  PT+T  S    T
Sbjct: 2012 ASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPS----T 2067

Query: 297  PLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA--- 353
             L   L SG      +S+P S     PL S   A   S   +  P+ E   P    A   
Sbjct: 2068 SLSEALSSGHSG---VSNPSSTTTEFPLFS---AASTSAAKQRNPETETHGPQNTAASTL 2121

Query: 354  ------------LPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASG----- 396
                         P G   +  +P P     S      + SE  +NP +   +S      
Sbjct: 2122 NTDASSVTGLSETPVGASISSEVPLP-MAITSRSDVSGLTSESTANPSLGTASSAGTKLT 2180

Query: 397  -VMSAPPVRAL-------DSGAMSTPLMGAPASGNMSTLQKTV---PASGAMTTSLMTVP 445
              +S P   +L       D   +S PL   P +   +++       P    + + ++  P
Sbjct: 2181 RTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDTP 2240

Query: 446  SSGVMSTEQMSATAS-------------------RVMSAQLTMAKTSGAMPT-GSMKAVA 485
            S G  S   +S + S                   R +S+ LT   TS   P  G   + A
Sbjct: 2241 SDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISS-LTHELTSRVTPIPGDWMSSA 2299

Query: 486  KQYKRATASGKMSTPLRRAPTSGAMSTQPVTATAS----ETMSMPQLT------------ 529
               K   AS  ++   RR  TS A +T P+  TAS     T+S+   T            
Sbjct: 2300 MSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARK 2359

Query: 530  ---VPA-SGSMSMLQMRAPVSEAMSMPQMR----TMASGLTSAAQMKAMTSGAMSTPLMT 581
               +P+ S S S L   +  S  M + +      T  SG+T+++     +S     P  T
Sbjct: 2360 TNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTST 2419

Query: 582  AQTSGSTSTLLMRDT-----ASGVMSCPQMRSLASGALSKPLMTPKA-------SGTMFT 629
             +T+ +TS  +  +T      S V   P   +L    ++ P+ T  A         T  T
Sbjct: 2420 TETNTATSPSVSSNTYSLDGGSNVGGTPS--TLPPFTITHPVETSSALLAWSRPVRTFST 2477

Query: 630  EKMTTTASEAMPTLLMR-----------DTVSGALSMPQM--TDTASGGLSASLMRDTAS 676
               T TAS   PT                +V     +P M    T+  G + SL+  T  
Sbjct: 2478 MVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIE 2537

Query: 677  GAMS-TSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG----- 730
             A + T  ++A V  G S             ASL+    S  + S P +   P       
Sbjct: 2538 PATAFTPHLSAAVVTGSS---------ATSEASLLTTSESKAIHSSPQTPTTPTSGANWE 2588

Query: 731  MSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSS 790
             S +P   +        + TS ++ T T+      T+STP      P + PS  T + +S
Sbjct: 2589 TSATPESLLVVTETSDTTLTSKILVTDTI---LFSTVSTP------PSKFPSTGTLSGAS 2639

Query: 791  ------GEMSLPLMRAPASGEIA-----TPLRSPAYGAM-SAPQMTATASGMMS------ 832
                     ++PL     +  +A     TPL + A  ++ + P+ T T S   +      
Sbjct: 2640 FPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVL 2699

Query: 833  ---SMPQVKAP---ISGAMSMPLTRSTAS-------------GGMSMPLMRAP------- 866
               S P    P   I G    PL  S+ S             G +++ L   P       
Sbjct: 2700 KTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSL 2759

Query: 867  ----DSRVTSTSQMMPTASG-------DMCTLPVRAPASGGVSSPLVRAPASGTMST-PL 914
                 S  + T+ ++ +++G        + T      +SGG+ S    +  + T S+ PL
Sbjct: 2760 VFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPL 2819

Query: 915  RRPSACETVSTELMRASASGHMSTA------QTTAMVSG-----GMSKPLMRAPASGTMP 963
                   T  +E+     +   STA      + T+  SG       S    +A AS T  
Sbjct: 2820 TMNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTA 2879

Query: 964  MPL----MSAMASGEMSMPLMETMASG------ATSTLQTSVANSRSMSLSQT-TYTVSG 1012
             P      S +      +P ++T ++       + +T+  S A++ S SLS++       
Sbjct: 2880 PPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRA 2939

Query: 1013 RMATAPIRASASGARSTSFM---RASVSGSMPMPLPRATASGCG------MGMSMPQMTA 1063
            RM T+    SAS  +ST F      S S SM    PR   SG G        MS P  + 
Sbjct: 2940 RMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSK 2999

Query: 1064 TDSRGMSTPLMRASGPGTM-STPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSH 1122
              S   ST L  AS   T+ ST Q A    S+  I    S E  TS ++ TAS S+ TS 
Sbjct: 3000 ASSAMTSTSL--ASKLTTLFSTGQAARSGSSSSPISL--STEKETSFLSPTASTSRKTSL 3055

Query: 1123 MTATTPETAKPP 1134
                 P  A+ P
Sbjct: 3056 FLG--PSMARQP 3065



 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 221/1085 (20%), Positives = 407/1085 (37%), Gaps = 150/1085 (13%)

Query: 139  SPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAP 198
            SPG M  P   ++  T      S+  S L++PA +S    +P+ ST   +  S  L   P
Sbjct: 8248 SPGDMLWPSQSSVEET------SSASSLLSLPATTSP---SPVSSTLVEDFPSASL---P 8295

Query: 199  DSGELSPILMQDMN-------PGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALA 251
             +  L+P L+   +       PG  ST  + + S E ++ L+ T  DTE M     TA+ 
Sbjct: 8296 VTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDT-VDTEDMQPSTHTAVT 8354

Query: 252  SGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLL 311
            +   S   +SG +S+       S+V S   +P+ TS   +    T  M +    I +S  
Sbjct: 8355 NVRTS---ISGHESQ-------SSVLSDSETPKATSPMGT----TYTMGETSVSISTSDF 8400

Query: 312  MSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSG----VMPTQTMPAP 367
              +   ++  T  L+   +G   T       +      +++ +PSG    V  T+ + + 
Sbjct: 8401 FETSRIQIEPTSSLT---SGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSR 8457

Query: 368  GSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTL 427
            G+    P        +   +P +   A   +S  P+    + +  T   G+P + +  TL
Sbjct: 8458 GTSMSGP-------DQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTL 8510

Query: 428  QKTVPA---------------SGAMTTSLMT-----VPSSGVMSTEQMSATASRVMSAQL 467
                                 S +  T+LM+     VP   + S E+ S+ +S + S  +
Sbjct: 8511 TLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAM 8570

Query: 468  TMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQP-VTATASETMSMP 526
            T       +P     +        T     +T + R  +    S+ P +++T++E ++  
Sbjct: 8571 TSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATS 8630

Query: 527  QLT-----VPASGSMSMLQMRAPVSEAMS--------------MPQMRTMASGLTSAAQM 567
            ++T     +  S +  ++ +   + + +S               P   T   G TS +  
Sbjct: 8631 EVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTS 8690

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTP------ 621
                   M T   ++ TSG       ++T+S       +  + +GA +K   T       
Sbjct: 8691 TPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGR 8750

Query: 622  -----KASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSA--SLMRDT 674
                  A  T+  E  T T +     L    T +G+  M     T   G S+  +   DT
Sbjct: 8751 TSTPGPAQSTISPEISTETITRISTPL----TTTGSAEMTITPKTGHSGASSQGTFTLDT 8806

Query: 675  ASGAMSTSQMTATV----SGGMSMPLMRAQDPGVMPASLMRAKVS-GKMLSQPMSTQDPG 729
            +S A      +A        GM+ P+ R  +    P+     K S    L    +   P 
Sbjct: 8807 SSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPS 8866

Query: 730  GMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTS---ETMSTPLMR-TSDPGERPSLLT 785
             +  +P +S  +  +++ S  + VM   T    TS    T S P M  TSD     SL T
Sbjct: 8867 PLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSD----ESLAT 8922

Query: 786  RASSSGEMSLPLMRAPASGEIAT-PLRSPAYGAM-SAPQMTATASGMMSSMPQVKAPISG 843
              ++    ++ L    A  ++ T   R   Y +    P+ +   S +++S   +K  +S 
Sbjct: 8923 SKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTS-STIKDIVS- 8980

Query: 844  AMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVR 903
              ++P +       M       P  R TSTSQ + +A+    T+P +A  S  +   + +
Sbjct: 8981 -TTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSAT-KPSTVPYKALTSATIEDSMTQ 9038

Query: 904  APASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMP 963
              +S    +P  + +  + +STE++   ++  + T  T   ++     P           
Sbjct: 9039 VMSSSRGPSP-DQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSP----------- 9086

Query: 964  MPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASA 1023
                 A + G +++    T  SG  ST     ++S+  +L   T      ++   +  ++
Sbjct: 9087 ----GATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEAS 9142

Query: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTP--LMRASGPGT 1081
            S + S S    + S  +   LP +  S      S+P  +   S  + T   L  +S P T
Sbjct: 9143 SASFSLSSPVMTSSSPVSSTLPDSIHSS-----SLPVTSLLTSGLVKTTELLGTSSEPET 9197

Query: 1082 MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSF 1141
             S P  +    ++ EI A       T  + +T   +   +H + ++        K   S 
Sbjct: 9198 SSPPNLS---STSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSM 9254

Query: 1142 GMLTP 1146
            G+  P
Sbjct: 9255 GITYP 9259



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 244/1208 (20%), Positives = 451/1208 (37%), Gaps = 179/1208 (14%)

Query: 50   IVSTSASDPGGTSTQLMTSPVFDTMS-APLMGVP--------NSGALSPPLMPASDSGAL 100
            I++   S PG TS   +++P  DT + A   G P         S   +       D+   
Sbjct: 4092 ILAMQTSPPGATS---LSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQP 4148

Query: 101  SPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
            SP   P+ +  + S  L+P   + + S +L TS+    S        F + ++ L    D
Sbjct: 4149 SP---PSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTD 4205

Query: 161  SAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGEL---SPILMQDMNPGVMS 217
             + IS         G    P +S+++ EA+ST    + D+  +   +   + +M      
Sbjct: 4206 MSRISL------EPGTSLPPNLSSTAGEALST-YEASRDTKAIHHSADTAVTNMEATSSE 4258

Query: 218  TQPVPAPS--SEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSA 275
              P+P  +  S+A SPL  +    +  S    +   S E + +    + ++ +     S 
Sbjct: 4259 YSPIPGHTKPSKATSPLVTSHIMGDITSST--SVFGSSETTEIETVSSVNQGLQERSTSQ 4316

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVM------------STP 323
            VAS  T      T  S G  T  ++   +   S   +SSP   +             ST 
Sbjct: 4317 VASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTS 4376

Query: 324  LLSVPDAG--------------------EMSTLPKPAPDAEAMSPALM----TALPSGVM 359
            L+    +G                    + ST+P       A++P  M    T L S   
Sbjct: 4377 LIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGP 4436

Query: 360  PTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRA---LDSGAMST--- 413
               +  +P S A + + +      + + PP  +T  G  ++ PV A   L SG + T   
Sbjct: 4437 KDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDM 4496

Query: 414  ------PLMGAPASGNMSTLQKTVPASGAMTTSLMTV-PSSGVMSTEQMSATASRVMSAQ 466
                  P+  +P   N++     + A+ A TT + T+ PS     T   +A+++ V+ + 
Sbjct: 4497 LNTSMEPVTNSPQ--NLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHST 4554

Query: 467  LTMAK-----TSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGA-------MSTQP 514
            L ++      TS  +P  SM          +  G  +T +   PTS          + Q 
Sbjct: 4555 LPVSSEPSTATSPMVPASSM---GDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQE 4611

Query: 515  VTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGA 574
            + +T    + +  ++V A    + +++ +  +  +  P   T    + S A  +   S  
Sbjct: 4612 MNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPP 4671

Query: 575  M--STPLMTAQT--SGSTSTL-LMRDTAS--------GVMSCPQMRSLASGALSKPLMTP 621
            M  ST + T QT  SG+TS + L  DT++         V++     S  + A++  +   
Sbjct: 4672 MTISTHMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDV 4731

Query: 622  KASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDT---ASGA 678
              +   F ++ ++ +S+A   +L+    S     PQ   T+S    +S++  +    +G 
Sbjct: 4732 SQTNPPFQDEASSPSSQA--PVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGK 4789

Query: 679  MSTSQMTATVS-GGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMK 737
            + TS  T T S   MS  L    D  V  A+    + +   ++  ++     G +     
Sbjct: 4790 VDTSLETVTSSPQSMSNTL---DDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHS 4846

Query: 738  SMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPL 797
            +++A       P    +++P V   T+ TM    +  S P    +  T   ++  ++  L
Sbjct: 4847 TVSA------YPEPSKVTSPNV---TTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKL 4897

Query: 798  MRAPASGEIATPLRSPAY------GAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTR 851
                 S EI +   +         GA +    T   S   +S P    P    +S+ ++ 
Sbjct: 4898 RETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFP---GPDQSTVSLDIST 4954

Query: 852  STASGGMSMPLMRAPDSRVTSTSQMMP--TASGDMCTL-PVRAPASGGVSSPLVRAPASG 908
             T +   + P+M    + +T T+Q  P    S D  T+ P       G+ S +    +  
Sbjct: 4955 ETNTRLSTSPIM-TESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQL 5013

Query: 909  TMSTPLRR-PSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPA--SGTMP-- 963
             ++T + R P      S             +   T+  S  +S P M  P+  S T+P  
Sbjct: 5014 DVTTLMSRIPQDVSWTSP-----------PSVDKTSSPSSFLSSPAMTTPSLISSTLPED 5062

Query: 964  ---MPLMSAMASGEMSM-PLMETMASGATSTLQTSVANSRSMSL----SQTTYTVSGRMA 1015
                P+ S + SG + +  ++ T     TS+L    + S  +      S+ T  +   + 
Sbjct: 5063 KLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSIN 5122

Query: 1016 TAPIRASASGARSTSFMRASVSGSMPMPLPR----ATASGCGMGMSMPQMTATDSRGMS- 1070
            T      A+ +   S   A      P    +     T        SMP   ++++  +  
Sbjct: 5123 TEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKR 5182

Query: 1071 ------TPLMRASGPGTMST--PQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSH 1122
                  TP +R +     S+    T+F +   P    T   E S++ +N ++  S P   
Sbjct: 5183 EPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTIT---EVSSTGVNSSSKISTPDHD 5239

Query: 1123 MTATTPET 1130
             +   P+T
Sbjct: 5240 KSTVPPDT 5247



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 263/1270 (20%), Positives = 452/1270 (35%), Gaps = 196/1270 (15%)

Query: 23    NKQMAFCRPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVP 82
             ++ +A  +  TET A + +  +     + +TSA     T     +SP F   +  +  V 
Sbjct: 9497  DESLAASKATTETEA-IHVFENTAASHVETTSA-----TEELYSSSPGFSEPTKVISPVV 9550

Query: 83    NSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGM 142
              S ++   ++  +  G+     +      +L+P L     S  ++    TS      P  
Sbjct: 9551  TSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSG 9610

Query: 143   MTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGE 202
              T P+         V P S      ++P P+        MS   S+ + T L  +P   E
Sbjct: 9611  AT-PEVSRTE----VMPSSRT----SIPGPAQST-----MSLDISDEVVTRLSTSPIMTE 9656

Query: 203   LSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDED-TEAMSKVLMTALASGEISSLLMS 261
              + I +       ++T  V  P   +M+ L  T    ++ +S   MT L S    SL  +
Sbjct: 9657  SAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWT 9716

Query: 262   G---TDSEAISSLIMSAVASGGTSP-QPTSTQNSGGIPTPLMSDLDSGIMSS--LLMSSP 315
                  ++   SS + S   +   SP   T   +S   P P+ S +  G++ +  +L +S 
Sbjct: 9717  SPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSS 9776

Query: 316   GSEVMSTPLLS-----VPDAGEMSTLPKPAPDAEAMSPALMTALP------------SGV 358
               +  S+P LS     +P   E+ T      D E + P+  TA+             S V
Sbjct: 9777  EPKTSSSPNLSSTSVEIPATSEIMT------DTEKIHPSSNTAVAKVRTSSSVHESHSSV 9830

Query: 359   MPTQ--TMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTP-- 414
             +     T+  P  G  S      V     SNP    T    +   P  +L  G   T   
Sbjct: 9831  LADSETTITIPSMGITSAVDDTTV---FTSNPAFSETRR--IPTEPTFSLTPGFRETSTS 9885

Query: 415   ------------LMGAPASGN--------MSTLQKTVPASGAMT------TSLMTVPSSG 448
                         L G P S          MS+ +  +P S   T      T ++T  SS 
Sbjct: 9886  EETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSS 9945

Query: 449   VMSTE--QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP- 505
              M +E  QM+ T  +        +  + A  T  +              +M+T + R+P 
Sbjct: 9946  SMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPE 10005

Query: 506   --------------TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSM 551
                           +S ++ + PVT + S + ++PQ    +S S++ L     V    + 
Sbjct: 10006 NPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTS 10065

Query: 552   PQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASG--VMSCPQMRSL 609
              +  T  S   S   ++ + +  ++T       S S +   +  T+SG  + S   + S 
Sbjct: 10066 TEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSE 10125

Query: 610   ASGALSKPLMTPKAS-----GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASG 664
              S A + P+ TP +       T       TT  EA P        SG        DT+S 
Sbjct: 10126 PSKA-TYPVGTPSSMAETSISTSMPANFETTGFEAEP---FSHLTSGFRKTNMSLDTSSV 10181

Query: 665   GLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMS 724
               + +     ++  + +S+   T S   S P      P     + +   +     + P  
Sbjct: 10182 TPTNTPSSPGSTHLLQSSKTDFTSSAKTSSP----DWPPASQYTEIPVDIITPFNASPSI 10237

Query: 725   TQDPGGMSMSPMK---SMTAGGMQMNS---PTSDVMSTPTVRAWTSETMS---------- 768
             T+  G  S    +   S+T     +++   P+++ +ST TV    SE M+          
Sbjct: 10238 TESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRA 10297

Query: 769   -----TPLMRT-SDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAM-SAP 821
                  +P  RT S PG+  + L+  + S   S P+   P S    T   S    A+    
Sbjct: 10298 ISGSGSPFSRTESGPGD--ATLSTIAESLPSSTPV---PFSSSTFTTTDSSTIPALHEIT 10352

Query: 822   QMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQM-MPTA 880
               +AT   + +S+    +   G + M  T  T+S           D+R+T + ++   T+
Sbjct: 10353 SSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTS 10412

Query: 881   SGDMCTLPVRAPASGGVSSPLVRAPAS----GTM--------STPLRRPSACETVSTELM 928
             +  + +L  R   + G+   + + P      GT+        ST    P    T  T+ M
Sbjct: 10413 AYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRM 10472

Query: 929   RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTM-PMPLMSAMASG-----EMSMPLMET 982
               + +   +T       S       +  P  GT+ P+     MAS       ++ P +  
Sbjct: 10473 ETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP 10532

Query: 983   MASGATSTLQTSVANSRSMSLSQTTYTVSGRMA--TAPIRASASGARSTSFMRASVSGSM 1040
                  TS+L TS+    S +L +TT +V  R +  TA + + +   RS       VS S 
Sbjct: 10533 DVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSE 10592

Query: 1041  P-------------MPL-----------------PRATASGCGMGMSMPQMTATDSRGMS 1070
             P             +P                    AT+ G  +  ++P   +       
Sbjct: 10593 PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDAL 10652

Query: 1071  TPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPET 1130
             TPL+  SG  T +T  T        E + T     + +   I  +    + H +  TP  
Sbjct: 10653 TPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSI 10712

Query: 1131  AKPPPKEVPS 1140
             A  P  E  S
Sbjct: 10713 ATSPGAETSS 10722



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 246/1147 (21%), Positives = 414/1147 (36%), Gaps = 177/1147 (15%)

Query: 47   QLPIVSTSASDPGGTS-TQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            +L    T A + G T+ TQ +T   F     P   +P S    P     S     SP   
Sbjct: 3093 ELTSSQTIAEEEGTTAETQTLT---FTPSETPTSLLPVSSPTEPTARRKS-----SPETW 3144

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEIS 165
             +S S      L+   D GTL   +  S            P   T S+    +P S E+S
Sbjct: 3145 ASSISVPAKTSLVETTD-GTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMS 3203

Query: 166  P-LAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAP 224
              L + +     +   I ST  +    TP    P    + P+ +Q    G  ST     P
Sbjct: 3204 TTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLP 3263

Query: 225  SSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLI-MSAVASGGTSP 283
            +    SP +   E+  A  +V ++  +  E  + L SGT      SL  MS+V+    SP
Sbjct: 3264 TGTT-SPTKSPTENMLATERVSLSP-SPPEAWTNLYSGTPGGTRQSLATMSSVSL--ESP 3319

Query: 284  QPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPG-------------SEVMSTPLLSVPDA 330
               S   +G   +P +    +G+  S+   S G             S ++  P+ S    
Sbjct: 3320 TARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSV 3379

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGS---------GAMSPWSTQNVD 381
              ++   K   +    +    TA+PS V+  + M A             + S WS Q   
Sbjct: 3380 SSLTDKSKHKTETWVST----TAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSG 3435

Query: 382  SEMM--SNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTT 439
            S++   ++P V  T            + S A +T L+  P SG+      T P+ G  ++
Sbjct: 3436 SDITLGASPDVTNTLY----------ITSTAQTTSLVSLP-SGDQGITSLTNPSGGKTSS 3484

Query: 440  -SLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMS 498
             S +T PS G+   E + A  S V S    +A T+G +   S  A        TA     
Sbjct: 3485 ASSVTSPSIGL---ETLRANVSAVKS---DIAPTAGHLSQTSSPAEVSILDVTTA----- 3533

Query: 499  TPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMA 558
                  PT G  +T     T S + + P    P  G  +M    A      S     T +
Sbjct: 3534 ------PTPGISTTITTMGTNSISTTTPN---PEVGMSTMDSTPATERRTTSTEHPSTWS 3584

Query: 559  SGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPL 618
            S  T+A+    +T   M++ L  A++ G+ ST+    T S + S  ++ S++        
Sbjct: 3585 S--TAASDSWTVTD--MTSNLKVARSPGTISTM---HTTSFLASSTELDSMS-------- 3629

Query: 619  MTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGA 678
             TP    T+    + T +S+A                   T+T++   + S    TAS  
Sbjct: 3630 -TPHGRITVIGTSLVTPSSDASAV---------------KTETSTSERTLSPSDTTASTP 3673

Query: 679  MSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKS 738
            +ST      +S  +         P ++  S   +    + +   M + D       P   
Sbjct: 3674 ISTFSRVQRMSISV---------PDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDP--- 3721

Query: 739  MTAGGMQMNSPTSDVM--STPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLP 796
                    N+P S  +  S  T+   T  ++S+    TS P         A++  E++L 
Sbjct: 3722 --------NTPLSTFLFDSLSTLDWDTGRSLSSATATTSAP-------QGATTPQELTLE 3766

Query: 797  LMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASG 856
             M +PA+ ++  P       +   P   A +SG+  S P   +  +   S  L  +T++ 
Sbjct: 3767 TMISPATSQL--PFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAH 3824

Query: 857  GMSMPLMRAPDSRVTSTSQMMPTASGD---MCTLPVRAPASGGVSSPLVRAPASGTMSTP 913
               +P   A    V   +   P A+        L   A A+    +   ++  S    T 
Sbjct: 3825 PGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAPWITE 3884

Query: 914  LRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRA----------------- 956
            +    + +T+      +S    ++T     + SG  S P  ++                 
Sbjct: 3885 MMNSVSEDTIKEVTSSSSVLRTLNTLDIN-LESGTTSSPSWKSSPYERIAPSESTTDKEA 3943

Query: 957  --PASGTMPMP--LMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSG 1012
              P++ T+     + S+  +   ++P     +   +  + TS      +S+S TT+  S 
Sbjct: 3944 IHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPEST 4003

Query: 1013 RMATAPIRASASGARSTS--FMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS 1070
            R  T P        R  S     +S + +  +  P +TA   G     P+   T S+ +S
Sbjct: 4004 RARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKG-----PRTEITSSKRIS 4058

Query: 1071 TPLMRASGPGTMSTPQTAFGVMSTPEIKATDSG----EASTSHINITASGSKPTSHMTAT 1126
            +  +  S   + S  +    + + P +  T+SG       TS    T S S PT   +AT
Sbjct: 4059 SSFLAQSMRSSDSPSEAITRLSNFPAM--TESGGMILAMQTSPPGAT-SLSAPTLDTSAT 4115

Query: 1127 TPETAKP 1133
               T  P
Sbjct: 4116 ASWTGTP 4122



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 228/1141 (19%), Positives = 417/1141 (36%), Gaps = 156/1141 (13%)

Query: 102  PLLMPASDSGALSPLLMPAL--DSGTLSPLLSTSEYGVMSPGMM------TIPDFGTMSA 153
            P + P   +G ++ L    +   S  ++    T+  G  S G++      T+   GT S 
Sbjct: 5537 PTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHST 5596

Query: 154  TLMVAPDSAEISPLAMPAPS--SGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDM 211
                 P S EI+ L    P   S +   P+  TSS  ++ +P M +P     SP      
Sbjct: 5597 VSQGFPHS-EITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSP-----SP------ 5644

Query: 212  NPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSL 271
               V ST P   PSS    PL +T          L+T++                    L
Sbjct: 5645 ---VSSTSPESIPSS----PLPVT---------ALLTSV--------------------L 5668

Query: 272  IMSAVASGGTSPQP-TSTQNSGGIPTP--LMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            + +    G TSP+P TS+  +   PT   L +  D+    ++  S   +  ++    S+ 
Sbjct: 5669 VTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVANVGTSIS 5728

Query: 329  DAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV-----DSE 383
                 S++P  +  ++A SP  +T        + + PA     +   ST ++     D+ 
Sbjct: 5729 GHESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTR 5788

Query: 384  MMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMT-TSLM 442
                       S V+S  P       + +  +  +  + +     K  P     T T L 
Sbjct: 5789 TSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLS 5848

Query: 443  TVP---SSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMST 499
            T P    S  M+    +     +  A LT+  +S A   G+   V +++  +  +  MS 
Sbjct: 5849 TFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSR 5908

Query: 500  PLRRAPTSGAMSTQPVTATASETMSMPQLTVPAS----GSMSMLQMRAPVSEAMSMPQMR 555
              +        S +  T++ S  + +P +T  +S     S S      PV+  ++  + +
Sbjct: 5909 STKGVSWQSPPSVEE-TSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRK 5967

Query: 556  T--MASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTL-LMRDTASGVMSCPQ-MRSLAS 611
            T  M    +        ++ + S  ++T++ S +T T+    +TA   M     M  L S
Sbjct: 5968 TIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHS 6027

Query: 612  GAL--SKPL--MTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLS 667
                 S+P     PK +G+M  + + +T++   P     D  S +   P++ + ++    
Sbjct: 6028 SVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDST---- 6083

Query: 668  ASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAK---VSGKMLSQ--- 721
            A +M  T       S ++   +  +S   +   DP  MPAS    K   +S +  S    
Sbjct: 6084 ALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSN 6143

Query: 722  -----------------PMSTQDPGGMSMSPMKSMTAGGMQ---------------MNSP 749
                             P      G +++      T+ G                 MN+ 
Sbjct: 6144 SPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNND 6203

Query: 750  TSDVMSTPTVRAWTSETMST--PLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIA 807
             +DV+ T    A  + ++S+  PL+ T+ P    S L   S+S  +S+  +  P   +I 
Sbjct: 6204 LNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKI- 6262

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPD 867
            T + +       +PQ          +            +      T S         +PD
Sbjct: 6263 TDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPD 6322

Query: 868  SR-VTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTE 926
            S    +TS ++ T++     +    P S  +    + +  + ++   LR  S  + + + 
Sbjct: 6323 SDPYKATSAVVITSTSGDSIVSTSMPRSSAMKK--IESETTFSLIFRLRETSTSQKIGSS 6380

Query: 927  LMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASG 986
               ++      TA TT +    ++    R    GT   P MS   S   S+ ++ T A  
Sbjct: 6381 SDTSTVFDKAFTAATTEVSRTELTSS-SRTSIQGT-EKPTMSPDTSTR-SVTMLSTFAGL 6437

Query: 987  ATS---TLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARS-------TSFMRASV 1036
              S   T+ T     R+ S    T+  S   + A   ++ +   S       TS +   +
Sbjct: 6438 TKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYI 6497

Query: 1037 SGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPE 1096
            SG+ P P    T+S   + +S+P +T+      + P  R S P  +++  T+ G++ T +
Sbjct: 6498 SGTSP-PSVEKTSSSSSL-LSLPAITSPSPVPTTLPESRPSSPVHLTSLPTS-GLVKTTD 6554

Query: 1097 IKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPALCYLLEEQE 1156
            + A+         +         TSH   TT E  K   K  PS  +    +     E+E
Sbjct: 6555 MLAS---------VASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKE 6605

Query: 1157 A 1157
            +
Sbjct: 6606 S 6606



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 207/972 (21%), Positives = 350/972 (36%), Gaps = 167/972 (17%)

Query: 48    LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPA 107
             +P ++ S  +P  T+  L+T P   + + P      +   S   +    S   SP    A
Sbjct: 11250 VPTLTVSTGEPF-TNISLVTHPAESSSTLPR----TTSRFSHSELDTMPSTVTSP---EA 11301

Query: 108   SDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDS-----A 162
               S A+S  + P +  G L+ L+++S   +              SAT    P+S     A
Sbjct: 11302 ESSSAISTTISPGIP-GVLTSLVTSSGRDI--------------SATFPTVPESPHESEA 11346

Query: 163   EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVP 222
               S +  PA +S  V     + S SE  +TP +                +PG  +T   P
Sbjct: 11347 TASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIAT--------------SPGAEATSDFP 11392

Query: 223   ----APSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEA-ISSLIMSAVA 277
                 +P    M   Q+T   T+    +    L+SGE  +     T SE   SS I +   
Sbjct: 11393 TITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPV 11452

Query: 278   SGGTSPQPTSTQNSGG------IPTPLMSDLDSGIMSSLLMSSPGSEVM---STPLLSVP 328
             S G S   TS   S G       PT   +  +    +  L+    +  M   +TP  S  
Sbjct: 11453 SPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHS 11512

Query: 329   DAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNP 388
              +     +   +P  EA S    T +   +    T   P SG     +  +     +S  
Sbjct: 11513 KSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSG-----TDTSTTFPTLSET 11567

Query: 389   PVRATASGVMSAPPVRALDSGAMSTPLM---GAPASGNMSTLQKTVPASGAMTTSLMTVP 445
             P     +      P     + + + P     G+  + +M T       SG  TT++   P
Sbjct: 11568 PYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIP--P 11625

Query: 446   SSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             S   + T Q++++A+   +A  T+  + G   T +  A        T +G  + P+R  P
Sbjct: 11626 SIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHP----GTQTG-FTVPIRTVP 11680

Query: 506   TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +S     +P T  AS     PQ + P S + S     +P +  +     RT AS    +A
Sbjct: 11681 SS-----EPDTM-ASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEAS----SA 11730

Query: 566   QMKAMTSGAMSTPLMTAQ-TSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKAS 624
              +  ++ GA    ++T+Q TS   +T     T +     P+  +L S            +
Sbjct: 11731 VLTTISPGAPE--MVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPA 11788

Query: 625   GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQM 684
              T+F +   TTAS     L +R     + ++P  T                    ++S  
Sbjct: 11789 STVFPQVSETTAS-----LTIRPGAETSTALPTQT--------------------TSSLF 11823

Query: 685   TATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG--MSMSPMKSMTAG 742
             T  V+G   + L     PGV       AK +      P+ST  PG    +M P  +++ G
Sbjct: 11824 TLLVTGTSRVDLSPTASPGVS------AKTA------PLSTH-PGTETSTMIPTSTLSLG 11870

Query: 743   GMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPA 802
              ++    T+ +++T +    ++ET ++ L  T  P           SS  ++    +   
Sbjct: 11871 LLE----TTGLLATSS----SAETSTSTLTLTVSPA------VSGLSSASITTDKPQTVT 11916

Query: 803   SGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPL 862
             S    T   SP+  ++  P+ + T +G   ++      I   M  P   S   G     +
Sbjct: 11917 SWNTET---SPSVTSVGPPEFSRTVTGTTMTL------IPSEMPTPPKTSHGEGVSPTTI 11967

Query: 863   MRAPDSRVTS--TSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSAC 920
             +R      T+  T+   PT +    T    A                G++ TPL  P   
Sbjct: 11968 LRTTMVEATNLATTGSSPTVAKTTTTFNTLA----------------GSLFTPLTTPGMS 12011

Query: 921   ETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMP--MPLMSAMASGEMSMP 978
                S  +   ++  H S   TT+  +     P    P + T    +   S  +S   ++P
Sbjct: 12012 TLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIPSSTAATVP 12071

Query: 979   LMETMASGATST 990
              M       T T
Sbjct: 12072 FMVPFTLNFTIT 12083



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 257/1224 (20%), Positives = 445/1224 (36%), Gaps = 195/1224 (15%)

Query: 76   APLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPL---LMPALDS-----GTLS 127
            APL+   +   ++  L   S S  +S   +P      ++ +   L P   S      TL+
Sbjct: 6225 APLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLA 6284

Query: 128  PLLSTSEYGVMSPGMMT-IPDFGTMSAT----LMVAPDS----AEISPLAMPAPSSGVVC 178
               +T++   M P + T + + GT S+       V+PDS    A  + +        +V 
Sbjct: 6285 TSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVS 6344

Query: 179  TPIMSTSSSEAMSTPLMLA--------------PDSGELSPILMQDMNPGVMSTQPVPAP 224
            T +  +S+ + + +    +                S + S +  +               
Sbjct: 6345 TSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELT 6404

Query: 225  SSEAMSPLQITDE-----DTEAMSKVLMTALAS---GEISSLLMSGTDSEAISSLIMSAV 276
            SS   S +Q T++     DT   S  +++  A     E  ++        A S   ++  
Sbjct: 6405 SSSRTS-IQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWD 6463

Query: 277  ASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGS---EVMSTPLLSVPDAGEM 333
             S  TS   T +  + G     +S L S +   +  +SP S      S+ LLS+P     
Sbjct: 6464 TSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSP 6523

Query: 334  STLPKPAPDAEAMSPALMTALP-SGVMPTQTMPA------PGSGAMS---PWSTQNV-DS 382
            S +P   P++   SP  +T+LP SG++ T  M A      P  G+ S   P +++++ D+
Sbjct: 6524 SPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDT 6583

Query: 383  EMM------SNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGA 436
            E M      +   V  T S   S   V A       T  M    +   + +  ++P S  
Sbjct: 6584 EKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSE 6643

Query: 437  MTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMA---KTSGAMPTGSMKAVAKQYKR--- 490
            +T   M    S     +  S +   ++S + +      T+GA  T   +  + +      
Sbjct: 6644 ITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPG 6703

Query: 491  -----------------------ATASGKMSTPLRRAPTSGAMS------TQPVTATASE 521
                                    T S  M+   R  P  G+ S        P T++ + 
Sbjct: 6704 PDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAG 6763

Query: 522  TMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPL-M 580
            T SM     P S  M+ +  + P   + ++P      S  +S     AMTS  +S+ L  
Sbjct: 6764 THSMATQEFPHS-EMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPK 6822

Query: 581  TAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAM 640
            T  T+ S  T L+  T S VM+   + +      S P      S  + T    TTA EA 
Sbjct: 6823 TIHTTPSPMTSLL--TPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEA- 6879

Query: 641  PTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQ 700
                M  + S A +  + T +  G  S+ L     + A +    T+T+            
Sbjct: 6880 ----MHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMG----------- 6924

Query: 701  DPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMS-TPT- 758
                +  S+  +  + K+  +   +  PG    S  ++ +      ++ TS V+S  PT 
Sbjct: 6925 -HTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNAS-----FSTDTSIVLSEVPTG 6978

Query: 759  VRAWTSETMSTPLMRTSDPGER-----PSLLTRA----------SSSGEMSLPLMRAPAS 803
              A  S T  T   RTS PG       P + TR           + S EM++P    P+ 
Sbjct: 6979 TTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSG 7038

Query: 804  GEIATPLRSPAYGAMSAPQMTATAS----------------GMMS--SMPQVKAPIS--G 843
                  L        S  +  +T +                G MS  S P ++ P S   
Sbjct: 7039 STSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPS 7098

Query: 844  AMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLV- 902
             +S+P T S      ++P        VT +S  +P  S  + + PV        S  LV 
Sbjct: 7099 LLSLPATTSPPPISSTLP--------VTISSSPLPVTS-LLTSSPVTTTDMLHTSPELVT 7149

Query: 903  RAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPAS-GT 961
             +P   + ++  R  +  +T +TE +  S +   S  +  +      S  L  +  S  T
Sbjct: 7150 SSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKAT 7209

Query: 962  MPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTV--SGRMATAPI 1019
             PM + S     E +   + T     TS +Q    +S S  L +T  +V  S  + T+ +
Sbjct: 7210 SPMFITSTQ---EDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAV 7266

Query: 1020 RASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDS--RGMSTPLM--- 1074
             +  S   +T   R  V+ S      R + SG      +P+++ T    +  ++P++   
Sbjct: 7267 LSEVSIGATTEISRTEVTSS-----SRTSISGSAESTMLPEISTTRKIIKFPTSPILAES 7321

Query: 1075 -------RASGPGTMSTPQTAFGVMSTPEIKATDSGEAS-TSHINIT---ASGSKPTSHM 1123
                   + S PG+ S         +TP +  T S       H  IT   + G+      
Sbjct: 7322 SEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRP 7381

Query: 1124 TATTPETAKPPPKEVPSFGMLTPA 1147
            ++   E   PP  ++    M++P+
Sbjct: 7382 SSLPVEETSPPSSQLSLSAMISPS 7405



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 262/1280 (20%), Positives = 473/1280 (36%), Gaps = 218/1280 (17%)

Query: 53   TSASDPG--GTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            T++S P    TS +++T+   DT +   M    S A +     +S  G+ S +L  +  +
Sbjct: 6853 TTSSPPNLSSTSHEILTTDE-DTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKT 6911

Query: 111  GALSPL-LMPALDSGTLSPLLSTSEYGV---------MSPGMMTIP-----DFGT-MSAT 154
             A +P+     +   T+S  +S S             ++PG+          F T  S  
Sbjct: 6912 KATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIV 6971

Query: 155  LMVAPD--SAEISPL--------AMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELS 204
            L   P   +AE+S          ++P PS   V   I + + +   ++P M   +S E++
Sbjct: 6972 LSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMT--ESAEMT 7029

Query: 205  PILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALAS---GEISSLLMS 261
             I  Q    G  S   +   +S   S  +     T+      MT L S   G++S    S
Sbjct: 7030 -IPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMS--WQS 7086

Query: 262  GTDSEAISSLIMSAVASGGTSPQPTSTQ---NSGGIPTPLMSDLDSGIMSS--LLMSSPG 316
                E  SSL         TSP P S+         P P+ S L S  +++  +L +SP 
Sbjct: 7087 SPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPE 7146

Query: 317  SEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSG------ 370
                S P LS   + E  T  K   + EA+ P+  TA  +  +P+    +P S       
Sbjct: 7147 LVTSSPPKLS-HTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSET 7205

Query: 371  --AMSPW-------------------STQNVDSEMMSN--PPVRATASGVMSAPPVRALD 407
              A SP                     T  +  E +S+  P +R T S V ++  +    
Sbjct: 7206 SKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIET-- 7263

Query: 408  SGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQM-SATASRVMSAQ 466
            S  +S   +GA     +S  + T  +  +++ S  +     + +T ++     S +++  
Sbjct: 7264 SAVLSEVSIGATTE--ISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAES 7321

Query: 467  LTMAKTSGAMPTGSMKAVAKQYKRATASGKM---STPLRRAPTSGAMSTQPVTATASET- 522
              M   +   P GS          +T    +   ST  +R P S    T  V+  A +  
Sbjct: 7322 SEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEI--TTLVSRGAGDVP 7379

Query: 523  --MSMP-QLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMST-- 577
               S+P + T P S  +S+  M +P   + ++P     +S  +SA+    +T G + T  
Sbjct: 7380 RPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPA----SSHSSSASVTSLLTPGQVKTTE 7435

Query: 578  -------PLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTP---KASGTM 627
                   P  ++  S S++++ +  T+       ++   ++ A++K   +    ++  ++
Sbjct: 7436 VLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSV 7495

Query: 628  FTEKMTTTASEAMPTL-LMRDT----VSGALSMPQMTDTASGGLSASLMRDTASG----- 677
              +  TT A+ AM T+ +M DT    ++ ALS  +   +       + +R+T++      
Sbjct: 7496 LPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSL 7555

Query: 678  AMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMK 737
            A   + + + VS G +  + R +       S  R  +SG   S        G +      
Sbjct: 7556 ATEANTVLSKVSTGATTEVSRTE-----AISFSRTSMSGPEQSTMSQDISIGTIPRISAS 7610

Query: 738  SMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPL 797
            S+     +M   T    S  T+ +    T++     T    E  S++ +     EM+  +
Sbjct: 7611 SVLTESAKMTITTQTGPSESTLES----TLNLNTATTPSWVETHSIVIQGFPHPEMTTSM 7666

Query: 798  MRAPASGEIATPL----RSPAYGAMSAPQMTA---TASGMMSSMPQVKAPISGAM-SMPL 849
             R P      +P      SP    +S P +T+    ++  ++ +P    P++  + S P 
Sbjct: 7667 GRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPA 7726

Query: 850  TRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVR----------APASGGV-- 897
            T +   G  + P   +  S  T++ + + T      T  V           A  S G   
Sbjct: 7727 TTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKS 7786

Query: 898  -------SSPLVRAPASGTMSTPLRRPSACET--VSTELMRASASGHMSTAQTTAMVSGG 948
                   SSP+      G  S     P+  ET  + TEL  +   G   ++ +    SG 
Sbjct: 7787 QSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGT 7846

Query: 949  -MSKPLMRAPASGT----------MPMPLMSAMA-------------------SGEMSMP 978
             MS  L + P   T          +P P  S ++                   S E++M 
Sbjct: 7847 KMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMN 7906

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVS-----GRMATAPIRASASGARSTSFMR 1033
               T   GAT+   +++  S + SL+ T  T+S      +M+T   R     +  +  + 
Sbjct: 7907 T-HTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLL 7965

Query: 1034 ASVSGSMPMPLPRATASGCGMGMSMPQMTA----------TDSRGMSTPLMRASGPGTMS 1083
                 S  +    AT S   +  ++P+  +          T     +T ++  S     +
Sbjct: 7966 EKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTN 8025

Query: 1084 TP----QTAFGVMSTPEIKA------------------TDSGEASTSHINITASGSKPTS 1121
            +P     T+  +++T E+                    + SG  STS +   +  SK TS
Sbjct: 8026 SPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTS 8085

Query: 1122 HMTATTPETAKPPPKEVPSF 1141
             M  T+           P F
Sbjct: 8086 PMVITSTMEDTSVSTSTPGF 8105



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 266/1241 (21%), Positives = 447/1241 (36%), Gaps = 191/1241 (15%)

Query: 31   PMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLM-----GVPNSG 85
            P++ T A+  +  SH            PG       T+P F T+ +  +     G PNS 
Sbjct: 207  PVSMTPAETTVTDSHT-----------PG------RTNPSFGTLYSSFLDLSPKGTPNSR 249

Query: 86   ALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLST-SEYGVMSPGMMT 144
              +   +  S +G   P   P   S   S +   A  S + S L +  SE  + S   +T
Sbjct: 250  GETSLELILSTTGY--PFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLT 307

Query: 145  IP-DFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGEL 203
             P   G   A     P+SA   P +M   ++      + ST SS  + TP +    + E 
Sbjct: 308  SPLSPGVPEARASTMPNSA--IPFSMTLSNAETSAERVRSTISS--LGTPSISTKQTAET 363

Query: 204  S---PILMQDMNPGVMSTQPVPAPSSEAM-SPLQITDEDTEAMSKVLMTALASGEISSLL 259
                    + M+  + ST      +SE + SP  +    T A++    +     E ++  
Sbjct: 364  ILTFHAFAETMD--IPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTH 421

Query: 260  MSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEV 319
             S +  E   +L  S      ++P   S   +  +PT   + LDS I S   +SS     
Sbjct: 422  HSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSS----- 476

Query: 320  MSTPLLSVPDAGEMSTLPKPAPDAEAMSPALM-TALPSGVMPTQTMPAPGSGAMSPWSTQ 378
             S P   +   G  S     +  A   S  L  T   +    + T  +       P  TQ
Sbjct: 477  -SHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQ 535

Query: 379  NVDSE--MMSNPPVRATASGVMSAPPVRALDSG----------------AMSTPLMGAPA 420
             V++   M +  P  +T+        V ++ SG                  +  L+G   
Sbjct: 536  WVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGEST 595

Query: 421  SGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMS-ATASRVMSAQLTMAKTSGAMPTG 479
            +G  +T Q  VP   +MT    T  S G  +T  ++ ATAS   SA LT+A  +  +P  
Sbjct: 596  AGP-TTHQFAVPTGISMTGGSSTRGSQG--TTHLLTRATASSETSADLTLA--TNGVPVS 650

Query: 480  SMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSM- 538
               AV+K     TA+G  S+P    P     S   V++   ET S+         S+ + 
Sbjct: 651  VSPAVSK-----TAAG--SSP----PGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLT 699

Query: 539  -LQMRAPVSE-----------AMSMPQMRTMA------SGLTSAAQMKAMTSGAMSTPLM 580
             L  R P S            + S+P + + +      S  ++ +  KA +S    TP +
Sbjct: 700  PLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEI 759

Query: 581  TAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG--------TMFTEKM 632
            + +T  S++ L     ++   S  ++R+  S     PL  P  SG        T+ T   
Sbjct: 760  STKTKPSSAVLSSMTLSNAATSPERVRNATS-----PLTHPSPSGEETAGSVLTLSTSAE 814

Query: 633  TTTASEAMPTLLMRDTVS---GALSMPQMT--------DTASGGLSASLMRDTASGAMST 681
            TT +    PT  +    S     LS+P ++         T S  L  S      +   S 
Sbjct: 815  TTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSV 874

Query: 682  SQ--------MTATVSGGMSMPLMRAQDPGVMPASLMRAK--VSGKMLSQPMSTQDPGGM 731
            SQ         T   S  +  P+    D     ++   +   VS    +   S  +  G 
Sbjct: 875  SQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGS 934

Query: 732  SMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASS-S 790
            ++  +  +T G   M+    D  +       T+   ++P  +T  P    ++ T A+S S
Sbjct: 935  ALPKISHLT-GTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLS 993

Query: 791  GEMSLPLMRAPASGEI-ATPLRSPAYGAMSAPQMTATASGMMSS--MPQVKAPI------ 841
              + +    +PA+  + AT +R P+   ++        S  ++S  +P  K  I      
Sbjct: 994  ATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLD 1053

Query: 842  ----------SGAMSMPLTRSTASGGMSMPLMRAPDSRVTST----SQMMPTASGDMCTL 887
                      S   SM  T +  S  MS+   ++ D+  +ST    SQ + T S D+  L
Sbjct: 1054 TSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHL 1113

Query: 888  PVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTE--LMRASASGHMSTAQTTAMV 945
              R           +  P  GT S    + +A    S +    R++  G +S++ ++   
Sbjct: 1114 TSRE----------ITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTP 1163

Query: 946  SGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSL-- 1003
               MS        + +M   +M  + +   +MP + +  S   S + TS A  +S  +  
Sbjct: 1164 KVTMSSTFSTQRVTTSM---IMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPL 1220

Query: 1004 -----------------SQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPR 1046
                             + +TY  S    +  + A AS    ++      S   P     
Sbjct: 1221 DTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTP 1280

Query: 1047 ATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEAS 1106
             T       + +       S G S+P M A G     +       ++T + K T S + S
Sbjct: 1281 LTFPSIETHIHVSTARMAYSSG-SSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVS 1339

Query: 1107 TSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPA 1147
            T H   T   ++      + TP      PK   S  + +PA
Sbjct: 1340 TPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPA 1380



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 173/872 (19%), Positives = 311/872 (35%), Gaps = 101/872 (11%)

Query: 123  SGTLSPLLSTSEYGVMSPGM----MTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVC 178
            SGT  P  ++       P      MT     +   TL     +A     + P   S    
Sbjct: 2980 SGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKE 3039

Query: 179  TPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDED 238
            T  +S ++S +  T L L P      P ++  +    ++  P    +     P ++T   
Sbjct: 3040 TSFLSPTASTSRKTSLFLGPSMAR-QPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQ 3098

Query: 239  TEAMSKVLMTALASGEISSLLMSGTDSEAISSLI-----MSAVASGGTSPQPTSTQNSGG 293
            T A  +       + E  +L    T SE  +SL+         A   +SP+  ++  S  
Sbjct: 3099 TIAEEEG-----TTAETQTLTF--TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVP 3151

Query: 294  IPTPLMSDLDSGIMSSLLMSS-----------PGSEVMSTPLLSVPDAGEMSTLPKPAPD 342
              T L+   D  +++++ MSS           P  E  S+P  + P + EMST  K    
Sbjct: 3152 AKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSS 3211

Query: 343  AE-AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV----DSEMMSNPPVRATASGV 397
             E ++SP + + + +    T     P    + P + Q+      S  +S+ P   T+   
Sbjct: 3212 KEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTS--- 3268

Query: 398  MSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSA 457
                P ++     ++T  +    S   +         G    SL T+ S  + S    S 
Sbjct: 3269 ----PTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSI 3324

Query: 458  TASRVMSAQLTMAKTSG---AMPTGSMKAVA--KQYKRATASGKMSTPLRRAPTSGAMS- 511
            T +   S+   ++KT+G   +M  GS            +T+S  +  P+    +  +++ 
Sbjct: 3325 TGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTD 3384

Query: 512  -TQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQM---RTMASGLTSAAQM 567
             ++  T T   T ++P   +      +  Q    V EA S       +T  S +T  A  
Sbjct: 3385 KSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASP 3444

Query: 568  KA-----MTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASG--ALSKPLMT 620
                   +TS A +T L++  +     T L   +     S   + S + G   L   +  
Sbjct: 3445 DVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRANVSA 3504

Query: 621  PKASGTMFTEKMTTTASEA-----------MPTLLMRDTVSGALSMPQMTDTASGGLS-- 667
             K+        ++ T+S A            P +    T  G  S+   T     G+S  
Sbjct: 3505 VKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTM 3564

Query: 668  ----ASLMRDTASGAMSTSQMTATVSG----GMSMPLMRAQDPGVMPASLMRAKVSGKML 719
                A+  R T++   ST   TA         M+  L  A+ PG +      + ++    
Sbjct: 3565 DSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTE 3624

Query: 720  SQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGE 779
               MST         P   +T  G  + +P+SD  +  T  + +  T+S      S P  
Sbjct: 3625 LDSMST---------PHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPIS 3675

Query: 780  RPSLLTRASSSGEMSLPLMRAPASGE---IATPLRSPAYGAMSAPQMTATASGMMSSMPQ 836
              S + R S S    L     P+S E   +   + S  + +      T  ++ +  S+  
Sbjct: 3676 TFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLST 3735

Query: 837  VKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGG 896
            +      ++S     ++A  G + P     ++ ++  +  +P + G + +          
Sbjct: 3736 LDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITS---------- 3785

Query: 897  VSSPLVRAPASG-TMSTPLRRPSACETVSTEL 927
              +P   A +SG T S P       E  ST+L
Sbjct: 3786 AVTPAAMARSSGVTFSRPDPTSKKAEQTSTQL 3817



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 248/1152 (21%), Positives = 423/1152 (36%), Gaps = 195/1152 (16%)

Query: 44   SHVQLPIVSTSASDPGGT-STQLMTSPVFDTMSAPLMGVPN-SGALSPPLMPASDSGAL- 100
            SH  LP+ +++    GGT ST     P  +  +   MG  N S   +PP+   S   +L 
Sbjct: 5280 SHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLM 5339

Query: 101  --------SPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTI--PDFGT 150
                    SP+   +  S   SPL + AL +  L  + +T   G  SP  +T   P+  +
Sbjct: 5340 SSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVL--VTTTDVLGTTSPESVTSSPPNLSS 5397

Query: 151  MSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQD 210
            ++            +  AM   S+    T + ++ S     + ++   ++ + +P++   
Sbjct: 5398 ITHERPATYKDTAHTEAAMHH-STNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTT 5456

Query: 211  MNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               G  S   V   +       QI  E T ++S  L  +  S + SS   + T   A S 
Sbjct: 5457 STLGDTS---VSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNT---AFSY 5510

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMS-DLDSGIMSSLLMS---SPGSEVMSTPLLS 326
            +   A+     +   +S  +   +  P ++ D+ +G+++ L  S   +  +E+  T   +
Sbjct: 5511 VPTGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTT 5570

Query: 327  VPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
             P A     LP              T    G   T +   P S   +  S    D   M+
Sbjct: 5571 TPGATSQGILPWDTST---------TLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMT 5621

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
             PPV  T+SG        +L S +M++P   +P S   ST  +++P+S    T+L+T   
Sbjct: 5622 TPPVEETSSGF-------SLMSPSMTSP---SPVS---STSPESIPSSPLPVTALLT--- 5665

Query: 447  SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPT 506
            S +++T  +  T S      +T +  + + PT        Q +  T      T    A  
Sbjct: 5666 SVLVTTTNVLGTTS---PEPVTSSPPNLSSPT--------QERLTTYKDTAHTEAMHA-- 5712

Query: 507  SGAMSTQPVTATASETMS--MPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSA 564
              +M T    A    ++S    Q +VPA    S            + P   T A G TS 
Sbjct: 5713 --SMHTNTAVANVGTSISGHESQSSVPADSHTS----------KATSPMGITFAMGDTS- 5759

Query: 565  AQMKAMTSGAMSTPLMTAQTSGSTSTLL--MRDTASGVMSCPQMRSLASGALSKPLMTPK 622
              +   T     T + T     STS+L+  +RDT +                S+ + T  
Sbjct: 5760 --VSTSTPAFFETRIQTE----STSSLIPGLRDTRT----------------SEEINTVT 5797

Query: 623  ASGTMFTEKMTTTASEAMPTLLM---RDTVSG----ALSMPQMTDT---------ASGGL 666
             + T+ +E  TTT +E   T ++   R T+SG     +S    T+T          +G  
Sbjct: 5798 ETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGST 5857

Query: 667  SASLMRDTAS-GAMSTSQMTATVSG-----GMSMPLMRAQDPGVMPASLMRAKVSGKMLS 720
              ++   T   G +S + +T   S      G   P+ +         ++ R+       S
Sbjct: 5858 EMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQS 5917

Query: 721  QPMSTQDPGGMSMSPMKSMTA-----GGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTS 775
             P   +     S  P+ ++T+       +  +SPTS +  T  + +   +T+   ++ T 
Sbjct: 5918 PPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTID--MLDTH 5975

Query: 776  DPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGM----- 830
                  SL + +S SGE+         + E +T   +  +   +A     T + M     
Sbjct: 5976 SELVTSSLPSASSFSGEI--------LTSEASTNTETIHFSENTAETNMGTTNSMHKLHS 6027

Query: 831  ---MSSMPQVKAP--ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMC 885
               + S P    P  ++G+M      ST++ G   P  +  D    STS + P    D  
Sbjct: 6028 SVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPG--SPETKNVDR--DSTSPLTPELKEDST 6083

Query: 886  TLPVRAPASGGVSSPLVRAPASGTMS-------TPLRRP-SACETVSTELMRASASGHMS 937
             L + +          V   A+  +S        P   P SA  T S ++   ++S H +
Sbjct: 6084 ALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSN 6143

Query: 938  TAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVAN 997
            +   T            +  A+ T P        SG  S+  +    S   ++  T  A 
Sbjct: 6144 SPPLTISTH--------KTIATQTGP--------SGVTSLGQLTLDTSTIATSAGTPSAR 6187

Query: 998  SRSMSLSQTTYTVSGR----MATAPIRASASGARSTSFMRASVSGSMPMP----LPRATA 1049
            ++    S+TT  ++      + T+P   SA  A S S     +  + P P    L   + 
Sbjct: 6188 TQDFVDSETTSVMNNDLNDVLKTSPF--SAEEANSLSSQAPLLVTTSPSPVTSTLQEHST 6245

Query: 1050 SGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSH 1109
            S      S+P  T      M T L     P T S PQ     ++T E  AT         
Sbjct: 6246 SSLVSVTSVPTPTLAKITDMDTNL----EPVTRS-PQNLRNTLATSE--ATTDTHTMHPS 6298

Query: 1110 INITASGSKPTS 1121
            IN   +    TS
Sbjct: 6299 INTAVANVGTTS 6310



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 175/837 (20%), Positives = 307/837 (36%), Gaps = 115/837 (13%)

Query: 386  SNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVP--------ASGAM 437
            S+ P R+  +G  S      +DSG     L    ++G +   + T+P        AS   
Sbjct: 10   SSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLASPTS 69

Query: 438  TTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKM 497
            +    T  S GVMS+    +T+  +  ++    +TS ++        ++ Y   +    +
Sbjct: 70   SVVGRTTQSLGVMSSALPESTSRGMTHSE---QRTSPSLSPQVNGTPSRNYPATSMVSGL 126

Query: 498  STP-LRRAPTSGAMSTQPVTATAS-ETMSMP---QLTVPASGSMSMLQMRAPVSEAMSMP 552
            S+P  R + T G  + +  T T + ET S P   + TVP   S +         +   +P
Sbjct: 127  SSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIP 186

Query: 553  -----QMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMR 607
                  M+T A   T++ +   ++     T +  + T G T+              P   
Sbjct: 187  VKITSPMKTFADS-TASKENAPVSMTPAETTVTDSHTPGRTN--------------PSFG 231

Query: 608  SLASGALS-KPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGL 666
            +L S  L   P  TP + G    E + +T      +        G+    +++ +A    
Sbjct: 232  TLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSS-----PEPGSAGHSRISTSAPLSS 286

Query: 667  SASLMRDTAS--GAMSTSQMTATVSGGMSMPLMRAQDPGVMPAS--LMRAKVSGKMLSQP 722
            SAS++ +  S     S   +T+ +S G+            +P S  L  A+ S + +   
Sbjct: 287  SASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRST 346

Query: 723  MSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETM---------STPLMR 773
            +S+     +S +   + T       + T D+ ST   +   SE +         ST  + 
Sbjct: 347  ISSLGTPSIS-TKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALT 405

Query: 774  TSDPGE---RPSLLTRASSSGE-------MSLPLMRAPASGEIA--TPLRSPAYGAMSAP 821
            T+ P          T  S+SG+        S+  +   A GE +  T    P  G  +  
Sbjct: 406  TTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLD 465

Query: 822  QMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTAS 881
                + S + SS P  +   +G+ S   + STA+ G S  ++RA  S  +  S     ++
Sbjct: 466  SKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHG-SSDILRATTSSTSKASSWTSEST 524

Query: 882  GDMCTLP--------------VRAPASGGVSSPLVRA-PASGTMSTPLRRPSAC-----E 921
                + P               R PAS  V++P+  + P+  +  T L+  S       E
Sbjct: 525  AQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEE 584

Query: 922  TVSTELMRASASG---HMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            T +  L+  S +G   H     T   ++GG S       + GT  + L  A AS E S  
Sbjct: 585  TSADTLIGESTAGPTTHQFAVPTGISMTGGSS----TRGSQGTTHL-LTRATASSETSAD 639

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
            L  T+A+       +   +  +   S    T       + +    S  +S++F   +  G
Sbjct: 640  L--TLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLG 697

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLM--------RASGPGTMSTPQTAFG 1090
              P+      +S        P          S PL+        + S   T S  +    
Sbjct: 698  LTPLNTRHPFSS------PEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSS 751

Query: 1091 VMS-TPEIKA-TDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLT 1145
            + + TPEI   T    A  S + ++ + + P     AT+P T   P  E  +  +LT
Sbjct: 752  ITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLT 808


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score =  102 bits (254), Expect = 3e-21
 Identities = 256/1144 (22%), Positives = 413/1144 (36%), Gaps = 158/1144 (13%)

Query: 64   QLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDS 123
            Q   +P   T    L  VP S    P         A+  +  P + +G     + PA  +
Sbjct: 450  QAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQA 509

Query: 124  GTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMS 183
            G     +++   GV     M +P   T SA   V   S ++S +A  A ++        +
Sbjct: 510  GKAPVTVTSLPAGVR----MVVP---TQSAQGTVIGSSPQMSGMAALAAAAA-------A 555

Query: 184  TSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMS 243
            T      S P +L+  +G  + +    + PG   T  +PA    A SP+ +++  T    
Sbjct: 556  TQKIPPSSAPTVLSVPAGT-TIVKTMAVTPG---TTTLPATVKVASSPVMVSNPAT---- 607

Query: 244  KVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPT-PLMSDL 302
            ++L TA A    S    + T +  I ++  S   +     Q  +T   G   T  L+   
Sbjct: 608  RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667

Query: 303  DSGIMSSLLMSSPG---SEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA--LPSG 357
             S    S L+S+ G   S V + P+ +    G+ ST P        ++  + T   LP+G
Sbjct: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGP--------VTQIIQTKGPLPAG 719

Query: 358  VMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMG 417
             +      A G       +TQ               ASG  + P +  + S + ST   G
Sbjct: 720  TILKLVTSADGKPTTIITTTQ---------------ASGAGTKPTILGISSVSPSTTKPG 764

Query: 418  APASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL-TMAKTSGAM 476
                   +T+ KT+P S  +T +  T  +S       ++   ++VM++     AK   A+
Sbjct: 765  T------TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818

Query: 477  P---TGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPAS 533
            P   TG  +    Q     A G+  T LR  P  G     PVT +A +      +    +
Sbjct: 819  PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878

Query: 534  GSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLM 593
            G  ++  +   VS +++       A G +        TS +++TP+ T  T  + S+ ++
Sbjct: 879  GVTTLGTVTGTVSTSLAG------AGGHS--------TSASLATPITTLGTIATLSSQVI 924

Query: 594  RDTASGVMSCPQMRSLASGALSKPLMT--PKASGTMFTEKMTTTASEAMP------TLLM 645
              TA  V S  Q    A+G L+ P +T  P +  T  T     +  EA P      ++L 
Sbjct: 925  NPTAITV-SAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILA 983

Query: 646  RDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRA---QDP 702
              T     +   + D+  G +    +    S     +  T T +   +  +        P
Sbjct: 984  SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043

Query: 703  GVMPASLMRAKVSGKMLSQPMSTQDPGGM---SMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
              +     R + +  +++  +  Q+   +   S  P ++   G       T++  +T T 
Sbjct: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG-------TTNTATTATS 1096

Query: 760  RAWTSETMSTPLMRTSDPGERPSLLTRASSSG-EMSLPLMRAPASGEIATPLRSPAYGAM 818
                    S P   T + G   +  T  SS G        RA A+G  A    S A GA+
Sbjct: 1097 NMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGAL 1156

Query: 819  SAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGG--MSMPLMRAPDSRVTSTSQM 876
             A Q     S       Q  A  S  M++  T +  S G  +   + R P  R  +  Q+
Sbjct: 1157 EAAQ----GSKSQCQTRQTSAT-STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211

Query: 877  MPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPS---ACETV-----STELM 928
             P +S    + P       G  S  V   A    S     P     CE++     ST + 
Sbjct: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271

Query: 929  RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEM--SMPLMETMASG 986
              +    +  + T   V    S P      +GT      S   S +   S P  ET  +G
Sbjct: 1272 VTALEALLCPSATVTQVC---SNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328

Query: 987  ATSTLQTSVANS--------------RSMSLSQTTYTVSGRMATAPIRASASGARSTSFM 1032
             T T  T+ +N               R     QTT T +    T  +   A    +TS  
Sbjct: 1329 TTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT----TMSVSVGALLPDATSSH 1384

Query: 1033 RASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVM 1092
            R   SG      P  T    G  +  P  T    R  S P       GT  T  T    M
Sbjct: 1385 RTVESGLEVAAAPSVTPQA-GTALLAPFPT---QRVCSNPPCETHETGTTHTATTVTSNM 1440

Query: 1093 ST---PEIKATDSGEASTSH---INITASGSKPTSHMTATT------------PETAKPP 1134
            S+   P   A+D GE  ++    +NIT+S +  T+  +  T            P  + PP
Sbjct: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500

Query: 1135 PKEV 1138
            P+E+
Sbjct: 1501 PEEL 1504



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 198/907 (21%), Positives = 348/907 (38%), Gaps = 128/907 (14%)

Query: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPAL---MTALPSGVM--PT----QTMPA-PGSGAM 372
            P+ SVP     S  P PA  A A+ P     +T LP      PT    Q +P  PGS   
Sbjct: 416  PVPSVPANPPKS--PAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSIS 473

Query: 373  SPWS--TQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM----ST 426
             P +  TQ V + +    P   T + +++  P  A  +G     +   PA   M     +
Sbjct: 474  VPTAARTQGVPAVLKVTGPQATTGTPLVTMRP--ASQAGKAPVTVTSLPAGVRMVVPTQS 531

Query: 427  LQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMS--AQLTMAKTSGAMP-TGSMKA 483
             Q TV  S    + +  + ++   + +   ++A  V+S  A  T+ KT    P T ++ A
Sbjct: 532  AQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPA 591

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRA 543
              K    A++   +S P  R   + A       ++A+ T + P +TV  SG++++ Q   
Sbjct: 592  TVKV---ASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648

Query: 544  PVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSC 603
             V+         T+  G+T       +    +S P       GS     +    S V + 
Sbjct: 649  VVT---------TVVGGVTKTI---TLVKSPISVP------GGSALISNLGKVMSVVQTK 690

Query: 604  PQMRSLASGALSKPLMT-------PKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMP 656
            P   S  +G  S   +T       P  +GT+   K+ T+A     T++     SGA + P
Sbjct: 691  PVQTSAVTGQASTGPVTQIIQTKGPLPAGTIL--KLVTSADGKPTTIITTTQASGAGTKP 748

Query: 657  QMTDTASGGLSASLMRDTASGAMSTSQMTA----------TVSGGMSMPL----MRAQDP 702
             +   +S  +S S  +   +  + T  M+A          T S G+  P+     +    
Sbjct: 749  TILGISS--VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTS 806

Query: 703  GV-MPASLMRA--KVS---GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMST 756
            G   PA ++ A  K++   G+     +  +   G   + ++++  GG+++ +P +     
Sbjct: 807  GTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVK 866

Query: 757  PTVRAWTSETMSTPLMRTSDPGERPSLLTRA---SSSGEMSLPLMRAPASGEIATPLRSP 813
            P V     +  +      +  G   + L  A   S+S  ++ P+        +++ + +P
Sbjct: 867  PAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINP 926

Query: 814  AYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST 873
                +SA Q T TA+G +++      P+S    + L  +  SG  + P+   P S + S 
Sbjct: 927  TAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLI-TAPSGVEAQPVHDLPVSILASP 985

Query: 874  SQMMPTASGDMCTLPVRAPASGGV---------SSPLVRAPASGTMSTPLR--------- 915
            +   PTA     T+ +     G V         S+P      +GT +T            
Sbjct: 986  TTEQPTA-----TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGH 1040

Query: 916  -RPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT--MPMPLMSAMAS 972
             +P+  + V      A++    +  Q    V    S P      +GT        S MA 
Sbjct: 1041 PQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAG 1100

Query: 973  GE-MSMPLMETMASGATSTLQTSVA--------NSRSMSLSQTTYTVSGRMATAPIRASA 1023
                S P  ET  +G T+T  T+++        ++R    + T   +   +AT  + A A
Sbjct: 1101 QHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEA-A 1159

Query: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS------TPL---M 1074
             G++S    R + + S  M +  AT + C  G  +    A +  G S       PL   +
Sbjct: 1160 QGSKSQCQTRQTSATSTTMTV-MATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218

Query: 1075 RASGPGTMSTPQTAFG-VMSTPEI--KATDSGEASTSHINITASGSKPTSHMTATTPETA 1131
            R S P     P       +ST  +   +  +GE   + +  +  G  P++ +T T  E  
Sbjct: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278

Query: 1132 KPPPKEV 1138
              P   V
Sbjct: 1279 LCPSATV 1285



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 247/1243 (19%), Positives = 427/1243 (34%), Gaps = 258/1243 (20%)

Query: 44   SHVQLPIVSTSASDPGGTST-QLMTSPVFDTMSAPL----MGVPNSGALSPPLMPASDSG 98
            + V + ++  +A  P  T+T Q++ +    ++S P      GVP   A+     P + +G
Sbjct: 441  TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP---AVLKVTGPQATTG 497

Query: 99   ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVM---SPGMMTIPDFGTMSATL 155
                 + PAS +G  +P+ + +L +G    + + S  G +   SP M  +      +A  
Sbjct: 498  TPLVTMRPASQAGK-APVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAAT 556

Query: 156  MVAPDSAEISPLAMPAPSSGV---VCTPIMST--SSSEAMSTPLMLAPDSGELSPILMQD 210
               P S+  + L++PA ++ V     TP  +T  ++ +  S+P+M++  +  +       
Sbjct: 557  QKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616

Query: 211  MNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTD------ 264
            +   V S       S+  +  +  +   T A    ++T +  G   ++ +  +       
Sbjct: 617  VGTSVSSATNT---STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGG 673

Query: 265  SEAISSL--IMSAVASGGTSPQPTSTQNSGGIPTPLMSD---LDSGIMSSLLMSSPGSEV 319
            S  IS+L  +MS V +        + Q S G  T ++     L +G +  L+ S+ G   
Sbjct: 674  SALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP- 732

Query: 320  MSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPG----SGAMSPW 375
              T +++   A    T P       ++SP+  T  P      +T+P       +GA    
Sbjct: 733  --TTIITTTQASGAGTKPTIL-GISSVSPS--TTKPGTTTIIKTIPMSAIITQAGATGVT 787

Query: 376  STQNVDSEM-MSNPPVRATASG----VMSAPPVRAL---DSGAMSTPLMGAPASGNMSTL 427
            S+  + S + +    V  + +G    +++A P  A      G     L GAP  G   T+
Sbjct: 788  SSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAP--GQPGTI 845

Query: 428  QKTVPASGAMTTSLMTVPS----------------------SGVMSTEQMSATASRVMSA 465
             +TVP  G    + +TV +                      +G +ST    A      ++
Sbjct: 846  LRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSAS 905

Query: 466  QLTMAKTSGAMPTGSMKA-------VAKQYKRATASGKMSTPLRRA-----PTSGAMSTQ 513
              T   T G + T S +        V+      TA+G ++TP         PT   + T 
Sbjct: 906  LATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITA 965

Query: 514  P------------VTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGL 561
            P            V+  AS T   P  TV  + S         V+   S P   T  +G 
Sbjct: 966  PSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGT 1025

Query: 562  TSAA----------------------QMKAMTSGAMST---------------PLMTAQT 584
            T+ A                      + +A  S   ST               P  T +T
Sbjct: 1026 TNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHET 1085

Query: 585  SGSTSTLLMRDTASGVMSC--PQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPT 642
              + +        +G   C  P   +  +G  +       + G           +   P 
Sbjct: 1086 GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPA 1145

Query: 643  LLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATV---SGGMSMPLMRA 699
            ++     +GAL      + A G  S    R T++ + + + M       +G +  P M  
Sbjct: 1146 VIRISVATGAL------EAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAR 1199

Query: 700  QDPGVMPASLMRAKVSGKM-LSQPMSTQDPGG-----MSMSPMKSMTAGG---------- 743
            +  G  PA +  A +S K+ LS P     P G     +S + M   + G           
Sbjct: 1200 EPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE 1259

Query: 744  -MQMNSPTSDVMSTPTVR-----AWTSETMSTPLMRTSDPGERPSLLTRASSSGEM--SL 795
             +Q  SP++ V  T         A  ++  S P   T + G   +  T  + S +   S 
Sbjct: 1260 SLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSN 1319

Query: 796  PLMRAPASGEIATPLRSPAYGAMSAP---------------QMTATASGMMSS----MPQ 836
            P      +G   T   + + G    P               Q T+T + M  S    +P 
Sbjct: 1320 PPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPD 1379

Query: 837  VKAP---ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTS------------------TSQ 875
              +    +   + +    S      +  L   P  RV S                  TS 
Sbjct: 1380 ATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSN 1439

Query: 876  MM------PTAS---------GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA- 919
            M       P AS         GD   +   +  +  VSS L RA  + T STP+  PS  
Sbjct: 1440 MSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVP 1499

Query: 920  --------------------CETVSTELMRASASGHMSTAQT-----------TAMVSGG 948
                                 ++ ST LM  SA   +S +QT           T   S G
Sbjct: 1500 PPEELQVSPGPRQQLPPRQLLQSASTALMGESAE-VLSASQTPELPAAVDLSSTGEPSSG 1558

Query: 949  MSKPLMRAPASGTMPMPLMSAMASGEMSMPL-METMASGATSTLQTSVANSRSMSLSQTT 1007
                     A+  +  P  +     ++S+P  +   A   T+TL  +      ++++   
Sbjct: 1559 QESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAA 1618

Query: 1008 YTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATAS 1050
               +   AT   +A A  A   +  +A +    PM    A A+
Sbjct: 1619 EAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 74/361 (20%), Positives = 134/361 (37%), Gaps = 53/361 (14%)

Query: 813  PAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSM-PLTRSTASGGMSMPLMRAPDSRVT 871
            PA  A +          + ++ P+  AP + A ++ PLT+     G+++    AP    T
Sbjct: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQV----GITLLPQAAPAPPTT 458

Query: 872  STSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRAS 931
            +T Q++PT  G   ++P  A   G  +   V  P   T  TPL            +  AS
Sbjct: 459  TTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP-QATTGTPL----------VTMRPAS 507

Query: 932  ASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTL 991
             +G      T+      M  P   A  +     P MS MA+   +    + +   +  T+
Sbjct: 508  QAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTV 567

Query: 992  -----QTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSM------ 1040
                  T++  + +++   TT   + ++A++P+  S    R      A V  S+      
Sbjct: 568  LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627

Query: 1041 -PMPLPRATASGCGMGMSMPQMTATDSRGMS-------TPLMRASGPGTMSTPQTAFGVM 1092
               P+     SG        Q+  T   G++       +P+    G   +S       V+
Sbjct: 628  STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVV 687

Query: 1093 STPEIKATD-SGEASTSHIN-----------------ITASGSKPTSHMTATTPETAKPP 1134
             T  ++ +  +G+AST  +                  +T++  KPT+ +T T    A   
Sbjct: 688  QTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTK 747

Query: 1135 P 1135
            P
Sbjct: 748  P 748


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens]
          Length = 1064

 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 189/972 (19%), Positives = 359/972 (36%), Gaps = 113/972 (11%)

Query: 181  IMSTSSSEAMSTPLMLAPDSGELSPI---LMQDMNPGVMSTQPVPAPSSEAMSPLQITDE 237
            I S S++ A  TP++    S  +S         ++    +T+  P P+    + +  T  
Sbjct: 183  ISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPV 242

Query: 238  DTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTP 297
             T   + V  T+  +  I+S       +  ++S+         T+ +PT+T     + + 
Sbjct: 243  FTTLKTAVTSTSPITSTITS-------TNTVTSMTT-------TTSRPTATNTLSSLMSN 288

Query: 298  LMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSG 357
            ++S             +  +  +ST + ++P     +T+ +  P +E   PA  T+  + 
Sbjct: 289  ILSSTPVPSTEMTTSHTTDTNPLSTLVTTLP-----TTITRSTPTSETTYPASPTSTVTD 343

Query: 358  VMPTQTMPAPGSGAMSPWST--QNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPL 415
                 T     +G +SP +T      S+  +  P+  T   V +     +  S   S+  
Sbjct: 344  STTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSLNFSSSA 403

Query: 416  MGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM-STEQMSATASRVMSAQLTMAKTSG 474
            + +  S + + +    P SG M TS   VP++ +      +     R+ +     ++T  
Sbjct: 404  IYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILLEVHDQRIQAKNPRYSQT-- 461

Query: 475  AMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASG 534
              P  S  A + +    T +  +ST    + T+   ST PV +  +   ++  +T  ASG
Sbjct: 462  --PFTSSTATSPETTTLTCTNDIST---ESLTTAMTSTTPVISAITPKTTVTSMTTTASG 516

Query: 535  SMSMLQMRAPVSEAMS---MPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTL 591
              +   + +  S  +S    P    + S  T+      + +   +    +  TS +T  +
Sbjct: 517  PTTTNTLSSLTSSILSSTPAPNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYPI 576

Query: 592  LMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSG 651
                T +  M+     +  +G  S     P  S ++ T +  TT     PT  + +T + 
Sbjct: 577  SPTGTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATT-----PTTNLGNTTT- 630

Query: 652  ALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMR 711
                 + T  ++   ++S +  T +  +ST+ +++      +M      +P  +   +  
Sbjct: 631  -----ETTSHSTPSFTSSAIYSTVN--ISTTTISSFPPSSGTMVTFTTMNPSSLSTDIST 683

Query: 712  AKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRA----WTSETM 767
              +  K ++QP                 + G     +  +D+ ST TV +     TS T 
Sbjct: 684  TTL--KNITQP-----------------SVGSTGFLTAATDLTSTFTVSSSSAMSTSVTP 724

Query: 768  STPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIAT--PLRSPAYGAMSAPQMTA 825
            S P ++  +     S  T  S +  M+L       +  I T  P+      +MSA     
Sbjct: 725  SAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSASSDWT 784

Query: 826  TASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMC 885
            T +  +SS P + + +       L  +T +   +   M  P + V +T     T +    
Sbjct: 785  TDTESISSAPAITSTLHTTAESTLAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTA 844

Query: 886  TL--PVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTA 943
            T         +  +S+     P   T  TP+          T  M  +AS   +T   ++
Sbjct: 845  TFLETTTLTPTTDISTESFMTPMIST--TPITSSMTLRNTMTS-MTTAASRPTTTNTLSS 901

Query: 944  MVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSL 1003
            + S  +S          + P+P    + S   +     T+ +   +T+ TS   S +   
Sbjct: 902  LTSSILS----------STPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYS 951

Query: 1004 SQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQ--- 1060
            +  T TV+          S +G  ST            + LP  T+S    G+SM     
Sbjct: 952  TSPTSTVTDSTTETTYSTSITGTLSTE-----------ISLPATTSSLITKGISMTSTRN 1000

Query: 1061 --MTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSK 1118
               T  ++   STP    +   T+ST  TA  + S P    T SG   TS    T + S 
Sbjct: 1001 LVTTTNENTSHSTPTFTLTIHSTISTSTTA--ISSVP----TTSGPIVTS---TTMTPSS 1051

Query: 1119 PTSHMTATTPET 1130
             T+ +  TT  T
Sbjct: 1052 LTADIPTTTLTT 1063



 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 181/833 (21%), Positives = 310/833 (37%), Gaps = 108/833 (12%)

Query: 388  PPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSS 447
            P   AT + + ++P  R L       P + +PA G+      T+  S   T    T+ SS
Sbjct: 31   PRAEATRTALSNSPHSRYLAEWPQGVPQLASPAPGHRENAPMTLTTSPHDTLISETLLSS 90

Query: 448  GVMSTEQMSATASRVMSAQLT-------MAKTSGAMPTGSMKAVAKQYKRATASGKMS-- 498
             V S    + T+      + T       +A T    PT  +  ++        + +++  
Sbjct: 91   LVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFIITISHPTSICVTTTQVTFT 150

Query: 499  -----TPLRRAPTSGAMSTQPVTATASETMSM------------PQLTVPASGSMSMLQM 541
                 TP+ + P +    T P+T T   T +M            P +TV  S S+S    
Sbjct: 151  SSYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATD- 209

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGS--TSTLLMRDTASG 599
                   +S     T  + L + +    M+   + T L TA TS S  TST+   +T + 
Sbjct: 210  -TTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTS 268

Query: 600  V---MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTT------TASEAMPTLLMRDTVS 650
            +    S P   +  S  +S  L +     T  T   TT      T    +PT + R T +
Sbjct: 269  MTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRSTPT 328

Query: 651  GALSMP-----QMTD-----TASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQ 700
               + P      +TD     T S  L+ +L   T     S+SQ T       +  L+   
Sbjct: 329  SETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTT 388

Query: 701  DPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNS---PTSDV---- 753
                  +SL     S   +   +ST      S+ P    T+G M  ++   PT+D+    
Sbjct: 389  TETTSQSSL---NFSSSAIYSTVSTSTTAISSLPP----TSGTMVTSTNIVPTADLKPEL 441

Query: 754  ----MSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSL--------PLMRAP 801
                +    ++A       TP   ++      + LT  +     SL        P++ A 
Sbjct: 442  ILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAI 501

Query: 802  ASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMP 861
                  T + + A G  +   +++  S ++SS P   AP +  ++   T +T    +   
Sbjct: 502  TPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTP---APNTEVITSHTTTTTPPSTLVTT 558

Query: 862  LMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPAS----GTMSTPLRRP 917
            L  A  +R T TS+          T P+    +G V+  +     S    GT ST    P
Sbjct: 559  LPTA-IARSTPTSE---------TTYPI--SPTGTVTDSMTEITYSTSMTGTWSTATTLP 606

Query: 918  -SACE--TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGE 974
             ++C   T+ T     +  G+ +T  T+       S P   + A  +      + ++S  
Sbjct: 607  LTSCSLPTIETATTPTTNLGNTTTETTS------HSTPSFTSSAIYSTVNISTTTISSFP 660

Query: 975  MSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRA 1034
             S   M T  +   S+L T ++ +   +++Q +   +G +  A    S     S+S M  
Sbjct: 661  PSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMST 720

Query: 1035 SVSGSMPMPLPR---ATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMS-TPQTAFG 1090
            SV+ S P    +      S         +MT T +    T  +  + P T S +P  +  
Sbjct: 721  SVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTSPVTYSFSPSMSAS 780

Query: 1091 VMSTPEIKATDSGEASTSHINITASGS-KPTSHMTATTPETAKPPPKEVPSFG 1142
               T + ++  S  A TS ++ TA  +  PT+  + TT    +PP   V + G
Sbjct: 781  SDWTTDTESISSAPAITSTLHTTAESTLAPTTTNSFTTSANMEPPSTAVATTG 833



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 125/596 (20%), Positives = 211/596 (35%), Gaps = 69/596 (11%)

Query: 557  MASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSK 616
            M  G TS     A  +G +ST   T+  +   +      T + + + P  R LA      
Sbjct: 1    MTHGFTSGFLCSAANAGTLSTATSTSHVTFPRAEA----TRTALSNSPHSRYLAEWPQGV 56

Query: 617  PLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSM-PQMTDTASGGLSASLMRDTA 675
            P +   A G      MT T S    TL+    +S  +S     T T+           T 
Sbjct: 57   PQLASPAPGHRENAPMTLTTSPH-DTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTV 115

Query: 676  SGAMSTSQMT------ATVSGGMSMPLMRAQ---DPGVMPASLMRAKVSGKMLSQPMSTQ 726
               ++T++         T+S   S+ +   Q        P  + +  V+    + PM+T 
Sbjct: 116  LVYLATTECVYPTSFIITISHPTSICVTTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTT 175

Query: 727  DPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTR 786
            + G  +M    S T       +P   V  + +V A T  T  T +  T+   ER  L T 
Sbjct: 176  EKGTSAMISSPSTTTA---RETPIVTVTPSSSVSA-TDTTFHTTISSTTRTTERTPLPT- 230

Query: 787  ASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMS 846
                G +   +   P    + T + S      S    T T++  ++SM       +   S
Sbjct: 231  ----GSIHTTMSPTPVFTTLKTAVTST-----SPITSTITSTNTVTSM-------TTTTS 274

Query: 847  MPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRA-- 904
             P   +T S  MS  L   P      T+    T +  + TL    P +   S+P      
Sbjct: 275  RPTATNTLSSLMSNILSSTPVPSTEMTTSHT-TDTNPLSTLVTTLPTTITRSTPTSETTY 333

Query: 905  PASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPM 964
            PAS         P++  T ST  +  S     + + TT +     S+     P + T  +
Sbjct: 334  PAS---------PTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKL 384

Query: 965  PLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYT-------VSGRMATA 1017
               +   + + S+    +      ST  T++++    S +  T T       +   +   
Sbjct: 385  VTTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPELILL 444

Query: 1018 PIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRAS 1077
             +      A++  + +   + S     P  T   C   +S   +T   +   +TP++ A 
Sbjct: 445  EVHDQRIQAKNPRYSQTPFTSSTATS-PETTTLTCTNDISTESLTTAMTS--TTPVISAI 501

Query: 1078 GPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKP-----TSHMTATTP 1128
                  TP+T    M+T     T +   S+   +I +S   P     TSH T TTP
Sbjct: 502  ------TPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITSHTTTTTP 551



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 32/245 (13%)

Query: 121  LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMS-ATLMVAPDSAEISPLAMPAPSSGVVCT 179
            L++ TL+P    S    M+P + T P   +M+    M +  +A   P      SS  + +
Sbjct: 847  LETTTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSS--LTS 904

Query: 180  PIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQ-ITDED 238
             I+  SS+   ST ++ +  +   SP  +    P  ++T    + ++ + SP   +TD  
Sbjct: 905  SIL--SSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDST 962

Query: 239  TEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPL 298
            TE      +T   S EIS            SSLI   ++   T    T+T  +    TP 
Sbjct: 963  TETTYSTSITGTLSTEISL-------PATTSSLITKGISMTSTRNLVTTTNENTSHSTPT 1015

Query: 299  MS-DLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA-LPS 356
             +  + S I +S           +T + SVP      T   P   +  M+P+ +TA +P+
Sbjct: 1016 FTLTIHSTISTS-----------TTAISSVP------TTSGPIVTSTTMTPSSLTADIPT 1058

Query: 357  GVMPT 361
              + T
Sbjct: 1059 TTLTT 1063



 Score = 38.9 bits (89), Expect = 0.035
 Identities = 82/387 (21%), Positives = 138/387 (35%), Gaps = 52/387 (13%)

Query: 784  LTRASSSGEMSLPLMRAPASGEIATP-LRSPAYGAMSAPQMTATASGMMSSMPQV--KAP 840
            L+ A+S+  ++ P   A  +    +P  R  A      PQ+ + A G   + P     +P
Sbjct: 19   LSTATSTSHVTFPRAEATRTALSNSPHSRYLAEWPQGVPQLASPAPGHRENAPMTLTTSP 78

Query: 841  ISGAMSMPLTRSTASGGMSM-PLMRAPDSRVTSTSQMMPTASGDMCTLP------VRAPA 893
                +S  L  S  S   S  P  +      T+   ++   +   C  P      +  P 
Sbjct: 79   HDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFIITISHPT 138

Query: 894  SGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPL 953
            S  V++  V   +S T  TP+ +        T  M  +  G      T+AM+S   +   
Sbjct: 139  SICVTTTQVTFTSSYT-PTPVTQKPVTTVTRTYPMTTTEKG------TSAMISSPSTTTA 191

Query: 954  MRAPASGTMPMPLMSAMASGEMSMPLMETMASGAT-----------------STLQTSVA 996
               P     P   +SA  +   +     T  +  T                 +TL+T+V 
Sbjct: 192  RETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVT 251

Query: 997  NSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGM 1056
            ++  ++ + T+      M T   R +A+   S+  + +++  S P+P    T S      
Sbjct: 252  STSPITSTITSTNTVTSMTTTTSRPTATNTLSS--LMSNILSSTPVPSTEMTTSH----- 304

Query: 1057 SMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASG 1116
                   TD+  +ST +       T STP +     ++P    TDS    T    +T + 
Sbjct: 305  ------TTDTNPLSTLVTTLPTTITRSTPTSETTYPASPTSTVTDSTTEITYSTVLTGTL 358

Query: 1117 S-----KPTSHMTATTPETAKPPPKEV 1138
            S      PTS    TT     P  K V
Sbjct: 359  SPTTTLPPTSSSQQTTETPMTPTTKLV 385


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 256/1189 (21%), Positives = 421/1189 (35%), Gaps = 177/1189 (14%)

Query: 50   IVSTSASDPGGT-STQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSP------ 102
            + S    +P GT S   + S V      P+  + +  A  P   P +     SP      
Sbjct: 191  VPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTT 250

Query: 103  ---LLMPASDSGALS---PLLMPA-LDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATL 155
               +L+   + G+LS   P+  PA L   T S  + TS      P   T PDF  +S   
Sbjct: 251  ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN--TPPDF-PISLGS 307

Query: 156  MVAP----DSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQ-D 210
             +AP        +  L    PS+  +  P + T S +  ST          + P+  + +
Sbjct: 308  HLAPLHQSSFGSVQLLGQTGPSA--LSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNE 365

Query: 211  MNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
            + P  ++  PV APS +       +   + + S  + T+ +    +SL++  + +     
Sbjct: 366  VVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHY 425

Query: 271  LIMSA--VASGGTSP-----------QPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGS 317
             +++   V+S GT+P            PT+T       +P MS   SG +S++  +SP +
Sbjct: 426  PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS---SGPISNIEPTSPAA 482

Query: 318  EVMSTPLLSVPDAGEMSTL----PKPAPDAEAMSPALMTALPSGVM---PTQ----TMPA 366
             VM+      P     +TL      P PD E +       LPS V+   PTQ    T+PA
Sbjct: 483  LVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKN-----LPSSVLVKFPTQKDLQTVPA 537

Query: 367  -----PGSGAMSPWSTQN-------VDSEMMSNPPVRATASGV-MSAPPVRALDSGAMST 413
                 P S A +  +T+        V +   ++P  ++T+S   +   P   L   ++  
Sbjct: 538  SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGE 597

Query: 414  PL-MGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKT 472
            PL +G PAS   S L     AS   T S     S+G +   + S     V +  L  A  
Sbjct: 598  PLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLL--KSSLITPTVAAFPLESADP 655

Query: 473  SGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTS-----GAMSTQPVTATASETMSMPQ 527
            +G  PT    A        TAS  +   +  AP +     G ++T P+  TASE   +  
Sbjct: 656  AGVAPT---TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAP 712

Query: 528  LTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGS 587
                    ++ L +   + +++  P +                      TP  T +  G 
Sbjct: 713  SPQNTCAPLATLVLAPEIPKSVPSPSLPPAG------------------TPPGTKKVDGI 754

Query: 588  TSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRD 647
            + T  +   AS    CP   S AS   S      K + T   +  +       P      
Sbjct: 755  SHTSALAPVASSPKECPTEDSGASATASS-----KGTLTYLADSPSPLGVSVSPQTKRPP 809

Query: 648  TVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPA 707
            T  G+       DT  G LS+ +           S + A+     S+    ++D      
Sbjct: 810  TKKGSAG----PDTPIGNLSSPV-----------SPVEASFLPENSLSFQGSKDSPATTH 854

Query: 708  SLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMS-TPTVRAWTSET 766
            S       G      ++   P G+++ P ++ T   + +  P     +  P      S T
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 767  MSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPA-SGEIATPLRSPAYGAMSAPQMTA 825
             S+P    + P  +  +    S  G  + P    P+  G  ATP  SP +    AP   A
Sbjct: 915  SSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSPKGGPATP--SPKW----APTPPA 967

Query: 826  TASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMC 885
                     P   +P         T  +  GG + P   +P    T  +   P+  G   
Sbjct: 968  ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP---SPKGAPTPPAVTPPSPKGS-- 1022

Query: 886  TLPVRAPASGGVSSPLVRAPAS---GTMSTPLRRPSACETVSTELMRASASGHMST---- 938
              P   P   G S+P    P S      +TPL  P    T     + +   G  +     
Sbjct: 1023 --PAATPFPKGASTPPAATPPSPKGSPAATPL--PKGAPTTPAATLPSPKGGPATPSLKG 1078

Query: 939  -----AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATST--- 990
                 A T     GG + P   +P    MP         G ++ P  +   +   +T   
Sbjct: 1079 APTPPAATPPSPKGGPATP---SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135

Query: 991  ----LQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPR 1046
                L T        + + T  +  G +AT P + + +   +T     S  G +  P P+
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATPSPK 1192

Query: 1047 ATASGCGMGMSMPQMTATDSRG-MSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEA 1105
               +        P  T    +G ++TP  + +     +TP +  G ++TP  K   +  A
Sbjct: 1193 GAPT-------TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245

Query: 1106 STSHINITASGSKPTSHM---TATTPETAK-----PPPKEVPSFGMLTP 1146
            +T         + P        A TP + K     PP K  P+  ++TP
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 200/939 (21%), Positives = 323/939 (34%), Gaps = 133/939 (14%)

Query: 58   PGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLL 117
            P G  T    +P     S      P   +  P   P S  G  SP   P       +P  
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG--SPAATPLPKGAPTTPAA 1062

Query: 118  -MPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGV 176
             +P+   G  +P L     G  +P   T P      AT   +P  A + P A P    G 
Sbjct: 1063 TLPSPKGGPATPSLK----GAPTPPAATPPSPKGGPAT--PSPKGAPMPPAATPPSPKGG 1116

Query: 177  VCTPIMSTSSSEAMSTP------LMLAPDSGELSPILMQDMNP--GVMSTQPVPAPSSEA 228
            + TP    + +   +TP      L   P  G  +       +P  G+ +  P  AP++ A
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 229  MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTST 288
             +P           S     A  S + +    + T       L   +     T+P  T  
Sbjct: 1177 ATP----------PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226

Query: 289  QNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSP 348
               GG+ TP               S  G+          P  G  +  PK AP   A +P
Sbjct: 1227 SPKGGLATP---------------SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 349  ALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAP-----PV 403
                +L  G+       AP    ++P S +   +   ++PP  A      + P     P 
Sbjct: 1272 P---SLKGGLATPPHKGAPNPAVVTPPSPKGGPA---TSPPKGAPTPPAATPPSPKGSPG 1325

Query: 404  RALDSGAMSTPLMGAPASGNMSTLQKTVPAS--GAMTTSLMTVPSSGVMSTEQMSATASR 461
                 GA + P +  P+     TL  T P+S  G  T S    P+    +       A  
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 462  VMSAQLTMAKTS--------GAMPTGSMKAVAKQYKRATAS----GKMSTP------LRR 503
              S +   A  S          +P    KA A    R  A+    G ++ P      L++
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 504  APTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTS 563
            AP + A    P T ++    ++P +T P+       +  A  S     P         T 
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505

Query: 564  AAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKA 623
             A + +      +TP         T+TLL + T +   +     +L   A++ P  +PK 
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA---TLAPKEALIPPAMTVP--SPKK 1560

Query: 624  SGTMFTEK---MTTTASEA-MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAM 679
            +  + T K    T ++ EA  P  +   T  GA S  ++       +  ++   +   A 
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL------IPPAVTSPSPKEAP 1614

Query: 680  STSQMT-ATVSGGMSMPLMRA--QDPGVMPASLMRAKVSGKMLSQPMSTQDP-GGMSMSP 735
            +   +T  +   G + P  +     P V P+SL  +  S   ++  M    P     +  
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674

Query: 736  MKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMS- 794
             K  TA    + +P  +  STP + A T +   T     + P   P    +  S G +S 
Sbjct: 1675 KKGPTALKEVLVAPAPE--STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732

Query: 795  ------LPLMRAPASGEIATPLRSPAYGAMSAPQMTA----TASGMMSSMPQVK-APISG 843
                  LP+ +  +             G ++ P+  A    TA+     +P+ + A +S 
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 844  AMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVR------------- 890
            A S P         +S+PL  +P   +    Q +P++ G +   P +             
Sbjct: 1793 APSPP---------VSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPL 1843

Query: 891  ---APASGGV--SSPLVRAPASGTMSTPLRRPSACETVS 924
                P SGGV   S LV  P   +   P+  PSA + V+
Sbjct: 1844 IPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 257/1206 (21%), Positives = 425/1206 (35%), Gaps = 190/1206 (15%)

Query: 49   PIVSTSASDP---------GGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGA 99
            P  ST AS P          GT+  L T+P   T    L+G        PP+ PA+ + A
Sbjct: 68   PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIG--------PPISPAALALA 119

Query: 100  LSPLLMPA--SDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFG---TMSA- 153
             SP++ P       + +PL + AL   ++    +     + SP  + + + G   T+SA 
Sbjct: 120  -SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAP 178

Query: 154  --------TLMVAPDSAEISPLAMPAP------------------SSGVVCTPIMSTSSS 187
                     L   P     +P   P+P                   SGV   P  + +++
Sbjct: 179  IAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTT 238

Query: 188  EAMSTPLMLAPDSGELSPILMQDMNPGVMSTQ-PVPAPSSEAMSPLQITDEDTEAMSKVL 246
             A+++P +       +S +L+   NPG +S + PV  P++ ++S        T+++  V 
Sbjct: 239  LAIASPQV---KDTTISSVLISPQNPGSLSLKGPVSPPAALSLS--------TQSLPVVT 287

Query: 247  MTALASGEISSLLMSGTDSEAISSLIMSAVAS----GGTSPQPTSTQNSGGIPTPLMSDL 302
             +   +G  +      +    ++ L  S+  S    G T P   S       PT     +
Sbjct: 288  SSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD------PTVKTISV 341

Query: 303  DSGIMSSLLMSSPGSEVMSTPLLS----VPDAGEMSTLPKPAPDAEAMSPALMTALPSGV 358
            D    SS   S P    +  PL S    VP       +  P+ D    + + +T  PSG 
Sbjct: 342  DH---SSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398

Query: 359  M---------PTQTM---PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRAL 406
            +         PT ++    +P +    P   Q   S + + P V      + +AP     
Sbjct: 399  LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE 458

Query: 407  DSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMST------------EQ 454
             +  +S P+    +SG +S ++ T PA+  M       PS+ V +T            E 
Sbjct: 459  VATCVSPPM----SSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPED 514

Query: 455  MSATASRVM-------SAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTS 507
            +    S V+         Q   A   GA P    +A     K  T    +    + +P+ 
Sbjct: 515  LKNLPSSVLVKFPTQKDLQTVPASLEGA-PFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF 573

Query: 508  GAMSTQPVTATASE-TMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMA-SGLTSAA 565
             + S+ P    + E T++   L  P         M +P+    S   ++T + +G  SA 
Sbjct: 574  QSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633

Query: 566  QM---KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPK 622
             +     +T    + PL +A  +G   T     +     + P +    S A   P   P 
Sbjct: 634  PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA---PKNHPV 690

Query: 623  ASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTS 682
              GT+ T  +  TASE  P              P   +T +   +  L  +      S S
Sbjct: 691  KEGTLTTLPLVPTASENCPVA------------PSPQNTCAPLATLVLAPEIPKSVPSPS 738

Query: 683  QMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAG 742
               A    G        +  G+   S +    S     +   T+D G  + +  K     
Sbjct: 739  LPPAGTPPGTK------KVDGISHTSALAPVASSP---KECPTEDSGASATASSKGTLTY 789

Query: 743  GMQMNSPTSDVMSTPTVRAWTSETMS---TPLMRTSDPGE--RPSLLTRASSSGEMSLPL 797
                 SP    +S  T R  T +  +   TP+   S P      S L   S S + S   
Sbjct: 790  LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD- 848

Query: 798  MRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGG 857
              +PA+    TP   P+      P      S    ++P  + P    +++P  +    G 
Sbjct: 849  --SPATTHSPTP---PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE---GP 900

Query: 858  MSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPA-SGTMSTPLRR 916
             +    +AP   +TS+S     A+     +P      G  + P    P+  G  +TP  +
Sbjct: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 917  ----PSACETVSTELMRASAS---GHMSTAQTTAMVSGGMSKPLMRA---PASGTMPMPL 966
                P A    S +   A+ S        A T     GG + P  +    P + T P P 
Sbjct: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 967  MSAMASG---EMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASA 1023
             S  A+      S P   T  S   S   T +      + + T  +  G  AT  ++ + 
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSR--GMSTPLMRASGPGT 1081
            +   +T     S  G    P P+        G  MP      S   G++TP  + +    
Sbjct: 1081 TPPAATP---PSPKGGPATPSPK--------GAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 1082 MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSF 1141
             +TP +  G ++TP  K   +  A+T   +     + P      TTP    P PK     
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPPPKGAPTTPAATPPSPKG---- 1184

Query: 1142 GMLTPA 1147
            G+ TP+
Sbjct: 1185 GLATPS 1190



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 262/1303 (20%), Positives = 428/1303 (32%), Gaps = 244/1303 (18%)

Query: 48   LPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPA------SDSGALS 101
            +P        P   +  L  S      +A  +G P    L PP  PA      S +   S
Sbjct: 9    VPATEQELPQPQAETAVLPMSSALSVTAA--LGQPGP-TLPPPCSPAPQQCPLSAANQAS 65

Query: 102  PLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDS 161
            P   P++ +     +  P   SGT  PL +  E     P ++  P      A L +A  S
Sbjct: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP---ISPAALALA--S 120

Query: 162  AEISPLAMPAPSS----GVVCTPIMSTSSSEAMSTPLMLAP------DSGEL----SPIL 207
              I+P     PSS     +V     S   S A    L+ +P      +SG +    +PI 
Sbjct: 121  PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180

Query: 208  MQD--MNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDS 265
              +   N   + ++ VP P      P  ++      ++   M ++ SG  S    + T +
Sbjct: 181  PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTP--MASIQSGVASLPQTTPTTT 238

Query: 266  EA----------ISSLIMSAVASGGTS------------------PQPTSTQNSGGIPTP 297
             A          ISS+++S    G  S                  P  TS+Q + G  TP
Sbjct: 239  LAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP 298

Query: 298  ------LMSDL----DSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMST---------LPK 338
                  L S L     S   S  L+   G   +S P +        ST         +  
Sbjct: 299  PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIP 358

Query: 339  PAPDAEAMSPALMTALPSGVMPTQTMPAP-GSGAMSPWSTQNVDSEMMSNP--------- 388
            P P    + PA + A P         P+   S   SP  + NV +    +P         
Sbjct: 359  PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSS 418

Query: 389  ---------------------PVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTL 427
                                 P+  T    ++A P    +     +P M   +SG +S +
Sbjct: 419  PNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPM---SSGPISNI 475

Query: 428  QKTVPASGAMTTSLMTVPSSGVMST------------EQMSATASRVM-------SAQLT 468
            + T PA+  M       PS+ V +T            E +    S V+         Q  
Sbjct: 476  EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV 535

Query: 469  MAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQP-VTATASETMSMPQ 527
             A   GA P    +A     K  T    +    + +P+  + S+ P +  +   T++   
Sbjct: 536  PASLEGA-PFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS 594

Query: 528  LTVPASGSMSMLQMRAPVSEAMSMPQMRTMA-SGLTSAAQM---KAMTSGAMSTPLMTAQ 583
            L  P         M +P+    S   ++T + +G  SA  +     +T    + PL +A 
Sbjct: 595  LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654

Query: 584  TSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMP-- 641
             +G   T     +     + P +    S A   P   P   GT+ T  +  TASE  P  
Sbjct: 655  PAGVAPTTAKGTSTYTTTASPFLEGTVSLA---PKNHPVKEGTLTTLPLVPTASENCPVA 711

Query: 642  -----------TLLMRDTVSGALSMPQM--------TDTASGGLSASLM----------- 671
                       TL++   +  ++  P +        T    G    S +           
Sbjct: 712  PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECP 771

Query: 672  -RDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKM----LSQPMSTQ 726
              D+ + A ++S+ T T       PL  +  P        +           LS P+S  
Sbjct: 772  TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS-- 829

Query: 727  DPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMR---TSDPGERPSL 783
             P   S  P  S++  G + +  T+   + P+ +   + +  TPL     T  P E P  
Sbjct: 830  -PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP-- 886

Query: 784  LTRASSSGEMSLPLMR-APASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPIS 842
                 +   ++LP  +  PA+     P ++PA    S+    A A+     +P   +P  
Sbjct: 887  -----TPSVVNLPFPKEGPAT---PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938

Query: 843  GAMSMPLTRSTASGGMSMPLMR--------------------APDSRVTSTSQMMPTASG 882
                   T  +  GG + P  +                    +P    T  +   P+  G
Sbjct: 939  APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998

Query: 883  DMCT-LPVRAPASGGVSSPLVRAPASGT-----MSTPLRRPSACETVSTELMRASASGHM 936
               T  P  AP    V+ P  +   + T      STP          S            
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058

Query: 937  STAQTTAMVSGGMSKPLMR---APASGTMPMPLMSAMASGEMSMPLMETMA-SGATSTLQ 992
            + A T     GG + P ++    P + T P P            P+            L 
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118

Query: 993  TSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGC 1052
            T        + + T  +  G +AT P + + +   +T     S  G +  P P+      
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLATPPPKGAP--- 1172

Query: 1053 GMGMSMPQMTATDSR-GMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEAST---- 1107
                + P  T    + G++TP  + +     +TP +  G ++TP  K   +  A+T    
Sbjct: 1173 ----TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228

Query: 1108 --SHINITASGSKPTSHMTATTPE--TAKPPPKEVPSFGMLTP 1146
                   +  G+  T   T  +P+   A PPPK  P+    TP
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 237/1147 (20%), Positives = 395/1147 (34%), Gaps = 147/1147 (12%)

Query: 49   PIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLM--PASDSGALSPLLMP 106
            P+V+       GT+  ++T+P     +AP      +  +SPP+   P S+    SP  + 
Sbjct: 426  PLVAQMPVSSVGTTPLVVTNPC-TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV 484

Query: 107  ASDSGALSPLLMPALDSGT-LSPLLSTSEYGVMSPGMMTIP-----DFGTMSATLMVAPD 160
             +      P    A      +SP L   E     P  + +      D  T+ A+L  AP 
Sbjct: 485  MAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544

Query: 161  S-------AEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNP 213
            S        +  P  +P   +    +P   ++SS   S  + L+P++      L + +  
Sbjct: 545  SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS---SPEIPLSPEATLAKKSLGEPL-- 599

Query: 214  GVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISS--LLMSGTDSEAISSL 271
                  P+  P+S   SPL +        + V+ T   +G  S+  LL S   +  +++ 
Sbjct: 600  ------PIGKPASSMTSPLGVNSS-----ASVIKTDSYAGPDSAGPLLKSSLITPTVAAF 648

Query: 272  IMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAG 331
             + +    G +P   +T       T   S    G +S    + P  E   T L  VP A 
Sbjct: 649  PLESADPAGVAP---TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS 705

Query: 332  EMSTLPKPAPD---AEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNP 388
            E   +  P+P    A   +  L   +P  V P+ ++P  G+    P  T+ VD   +S+ 
Sbjct: 706  ENCPVA-PSPQNTCAPLATLVLAPEIPKSV-PSPSLPPAGT----PPGTKKVDG--ISHT 757

Query: 389  PVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSG 448
               A  +      P    DSGA +T    A + G ++ L  +    G   +     P + 
Sbjct: 758  SALAPVASSPKECPTE--DSGASAT----ASSKGTLTYLADSPSPLGVSVS-----PQTK 806

Query: 449  VMSTEQMSA---TASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
               T++ SA   T    +S+ ++  + S  +P  S+     +   AT         + AP
Sbjct: 807  RPPTKKGSAGPDTPIGNLSSPVSPVEAS-FLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865

Query: 506  TSGA---MSTQPVTATASETM--SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASG 560
            T  A   +S + VT    ET   S+  L  P  G  +    +AP     S    +  A+ 
Sbjct: 866  TPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925

Query: 561  LTSAAQMKAMTSGAMSTPLMTAQTS-----------GSTSTLLMRDTASGVMSCPQMRSL 609
                        GA + P  T  +              T       +  G  + P  +  
Sbjct: 926  APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985

Query: 610  ASGALSKPLM------TPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTAS 663
             +   + P        TP   G      +T  + +  P         GA + P  T  + 
Sbjct: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT--PFPKGASTPPAATPPSP 1043

Query: 664  GGLSASLMRDTASGAMSTSQMTA-TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQP 722
             G  A+       GA +T   T  +  GG + P ++       PA+   +   G     P
Sbjct: 1044 KGSPAAT--PLPKGAPTTPAATLPSPKGGPATPSLKGAP--TPPAATPPSPKGGPATPSP 1099

Query: 723  MSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAW--TSETMSTPLMRTSDPGER 780
                 P   +    K   A      +PT+   + P+ +    T      P    + P   
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 781  PSLLTRASSSGEMSLPLMRAPA-SGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVK- 838
               L      G  + P    P+  G +ATP  SP  GA + P  T  +     + P  K 
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATP--SPK-GAPTTPAATPPSPKGGLATPSPKG 1216

Query: 839  APISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVS 898
            AP + A + P    +  GG++ P   +P    T+ +   P+  G     P   P  G  +
Sbjct: 1217 APTTPAATPP----SPKGGLATP---SPKGAPTTPAATPPSPKGG----PATPPPKGAPT 1265

Query: 899  SPLVRAPA-SGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAP 957
             P    P+  G ++TP  + +    V T     S  G  +T+      +   + P     
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTP---PSPKGGPATSPPKGAPTPPAATPPSPKG 1322

Query: 958  ASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATA 1017
            + GT P         G  + P +   +   T TL  +  +S+         T S +    
Sbjct: 1323 SPGTPP-------PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT-----TPSSKEGPT 1370

Query: 1018 PIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQM---TATDSRGMSTPLM 1074
            P  A+ S     +    S      +P P+   +   +    P+    T     G +TP  
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP-- 1428

Query: 1075 RASGPGTMSTPQ-TAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
                 G ++ P  T   +   P   A   G A+            P+S    T P    P
Sbjct: 1429 ---SKGDLTPPAVTPVSLKKAPATSAPKGGPAT------------PSSKGDPTLPAVTPP 1473

Query: 1134 PPKEVPS 1140
             PKE P+
Sbjct: 1474 SPKEPPA 1480



 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 237/1139 (20%), Positives = 388/1139 (34%), Gaps = 155/1139 (13%)

Query: 58   PGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLL 117
            P G     MTSP+    SA ++   +S A      P   S  ++P +       A    +
Sbjct: 600  PIGKPASSMTSPLGVNSSASVIKT-DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGV 658

Query: 118  MPALDSGTLSPLLSTSEY--GVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSG 175
             P    GT +   + S +  G +S      P       TL + P ++E  P+A   PS  
Sbjct: 659  APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVA---PSPQ 715

Query: 176  VVCTPIMSTSSSEAMSTPLMLAPD------SGELSPILMQDMNPGVMSTQPVPAPSSEAM 229
              C P+ +          L+LAP+      S  L P         V       A +  A 
Sbjct: 716  NTCAPLAT----------LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765

Query: 230  SPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQ 289
            SP +   ED+ A +    TA + G ++ L      +++ S L    V+    + +P + +
Sbjct: 766  SPKECPTEDSGASA----TASSKGTLTYL------ADSPSPL---GVSVSPQTKRPPTKK 812

Query: 290  NSGGIPTPL------MSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDA 343
             S G  TP+      +S +++  +    +S  GS+          D+   +  P P    
Sbjct: 813  GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK----------DSPATTHSPTPPSPK 862

Query: 344  EAMSPALMTAL-PSGVM--PTQT-------MPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
             A +P+ +T L P GV   P +T       +P P  G  +P   Q     M S+ P +A 
Sbjct: 863  GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPA--SGNMSTLQKTVPASGAMTTSLM----TVPSS 447
            A+      P      GA + P    P+   G  +   K  P   A T          PS 
Sbjct: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982

Query: 448  GVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGK-MSTPLRRAPT 506
                T   +AT         T +      P        K    AT   K  STP    P 
Sbjct: 983  KGAPTPP-AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041

Query: 507  S--GAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMR-------TM 557
            S  G+ +  P+   A  T +   L  P  G  +     AP   A + P  +         
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAAT-LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 558  ASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKP 617
             + +  AA   +   G  + P   A T+ + +      +  G ++ P  +   +   + P
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATP----PSPKGGLATPPPKGAPTTPAATP 1156

Query: 618  ------LMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLM 671
                  L TP   G   T   T  + +     L   +  GA + P  T  +  G    L 
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGG---LATPSPKGAPTTPAATPPSPKG---GLA 1210

Query: 672  RDTASGAMSTSQMTA-TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGG 730
              +  GA +T   T  +  GG++ P  +       PA+   +   G     P     P  
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGPATPPPKGAPTPPA 1268

Query: 731  MSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDP--GERPSLLTRAS 788
             +   +K   A      +P   V++ P+ +   +         TS P     P   T  S
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA---------TSPPKGAPTPPAATPPS 1319

Query: 789  SSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMP 848
              G    P  +   +    TP  SP  G  + P  T ++ G  ++    + P     + P
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTP-PSPK-GTPTLPATTPSSKGGPTTPSSKEGP-----TPP 1372

Query: 849  LTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASG 908
                +  GG +M            + +  PT+   +   P +APA+  V+      P+ G
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-VTREGAATPSKG 1431

Query: 909  TMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMS 968
             ++ P   P         L +A A+        T    G  + P +  P+    P P   
Sbjct: 1432 DLTPPAVTP-------VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484

Query: 969  AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARS 1028
            A +S     P   T A     TL   + +S    +  T  +    +A      S     +
Sbjct: 1485 ATSSSPKKAPA--TPAPMGAPTLPAVIPSSPK-EVPATPSSRRDPIAPTATLLSKKTPAT 1541

Query: 1029 TSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTA 1088
             +   A +  +M +P P+ T +                  + TP      P T S+ + +
Sbjct: 1542 LAPKEALIPPAMTVPSPKKTPA------------------IPTP---KEAPATPSSKEAS 1580

Query: 1089 FGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPA 1147
                 TP   +T  G  S   + I  + + P+     T P    P P++ P+    TPA
Sbjct: 1581 SPPAVTP---STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA----TPA 1632


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 250/1156 (21%), Positives = 402/1156 (34%), Gaps = 152/1156 (13%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPAS--- 108
            +T+ S  G  ST   +SP +   +        SG L       S +G+    L PAS   
Sbjct: 275  TTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTT 334

Query: 109  --------DSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
                     S   S    PA  SGT S  +  S     SP       F   S TL  + +
Sbjct: 335  HEGEPTTFQSWPSSKDTSPA-PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 393

Query: 161  SAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQP 220
            S                 TP+ S+  + A + P   +  SG +        +PG   T  
Sbjct: 394  S-----------------TPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMH 436

Query: 221  VPAPS-----SEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSG-----TDSEAISS 270
             P  S     SE  +    +   T++ +     ALA     S L S       DS  IS 
Sbjct: 437  FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 496

Query: 271  LIMSAVAS-GGTSPQPTSTQNSGGIPTPLMSD-----LDSGIMSSLLM----SSPGSEVM 320
                + AS        T+   +G  P+ L+ D     + SG M +  +    + PG    
Sbjct: 497  RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK 556

Query: 321  STPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV 380
            ST   S P + + + LP     +     +  T   S    T T   PGS  M   S ++ 
Sbjct: 557  STTFYSSPRSPDTTHLPASMTSSGVSEES--TTSHSRPGSTHTTAFPGSTTMPGLSQEST 614

Query: 381  DSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTS 440
             S     P     + G  +A  +     G   T     P S   + L     ASG +  S
Sbjct: 615  ASHSSPGPTDTTLSPGSTTASSL-----GPEYTTFHSRPGSTETTLLPDNTTASGLLEAS 669

Query: 441  LMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTP 500
             M V SS                    T +  +   P GS           T  G+ ST 
Sbjct: 670  -MPVHSS--------------------TRSPHTTLSPAGS----------TTRQGE-STT 697

Query: 501  LRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASG 560
                P+S    T+P   T +     P  T   S          P S   +    R+  SG
Sbjct: 698  FHSWPSSN--DTRPAPPTTTSAFVEPSTTSHGS----------PSSIPTTHISARSTTSG 745

Query: 561  LTSAAQMKAMTSGAMSTPLM----TAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSK 616
            L   +     + G+  T       T    G  ST     T   + S P   S      + 
Sbjct: 746  LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 805

Query: 617  PLMTPKASGTMFTEKMTTTASEAMPTLLMRDT--VSGALSMPQMTDTASGGLSASLMRDT 674
               +P ++ T      +TT+  +  ++    +   +G + +P  + T S  L  S     
Sbjct: 806  YHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARS-TNSVLLGESTTSPI 864

Query: 675  ASGAMSTSQMT-ATVSGGMSMPLMRAQDPGVMPA-SLMRAKVSGKMLSQPMSTQD--PGG 730
            +SG+M T+ +  +T + G+S            PA +L  A  +   +S+  +T    PG 
Sbjct: 865  SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGS 924

Query: 731  MSMSPM-KSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASS 789
               +    S T  G+  +S TS   S+P     T    ST      +P   P       S
Sbjct: 925  THTTAFPDSTTTPGLSRHSTTSH--SSPGSTDTTLLPASTTTXLVGEPTTSP------IS 976

Query: 790  SGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPL 849
            SG      +    +    +   +  Y +  +P  T + +   SS    ++  S +     
Sbjct: 977  SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1036

Query: 850  TRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGT 909
              +   G  +MP +    S+ ++ S   P ++    +      +S G  S    +    T
Sbjct: 1037 HTTAFPGSTTMPGV----SQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGST 1092

Query: 910  MSTPLRRPSACETVSTELMRASASGHMSTA--QTTAMVSG-----GMSKPLMRAPAS-GT 961
             +T L       T ++ L+ AS   H ST   +TT   +G     G S      P+S  T
Sbjct: 1093 ETTLL----PDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDT 1148

Query: 962  MPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRA 1021
            MP P  +  A  E+S     T + G+ S++ T+       S S TT+  S    T    +
Sbjct: 1149 MPAPPTTTSAFVELS-----TTSHGSPSSIPTT-----HFSASSTTFGRSEESTTVH-SS 1197

Query: 1022 SASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGT 1081
              + A + S  R++ SG +       ++ G    M  P+ +    R   +    +S   T
Sbjct: 1198 PVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 1257

Query: 1082 MST-PQTAFGVMSTPEIKATDSGEASTSHI--NITASGSKPTSHMTATTPET--AKPPPK 1136
            +S+ P T   ++  P    +  G  +T+H   + T SG    S  + ++P+T    P P 
Sbjct: 1258 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPA 1317

Query: 1137 EVPSFGMLTPALCYLL 1152
               + G +  +  + +
Sbjct: 1318 HFTTSGRIAESTTFYI 1333



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 234/1077 (21%), Positives = 380/1077 (35%), Gaps = 159/1077 (14%)

Query: 95   SDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSAT 154
            S   A++  ++PA  + ++       +   T SP+ S S      PG  T P     S T
Sbjct: 506  SSPDAMATTVLPAGSTPSV------LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTT 559

Query: 155  LMVAPDSAEISPLAMPAPSSGV----------------------VCTPIMSTSSSEAMST 192
               +P S + + L     SSGV                         P +S  S+ + S+
Sbjct: 560  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 193  PLMLAPDSGELSP--ILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTAL 250
            P    P    LSP       + P   +    P  +   + P   T       S  + ++ 
Sbjct: 620  P---GPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 676

Query: 251  ASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNS------------GGIPTPL 298
             S   +      T  +  S+   S  +S  T P P +T ++              IPT  
Sbjct: 677  RSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTH 736

Query: 299  MS--DLDSGIM--SSLLMSSPGSEVMSTPLLSVPDA------GEMSTLP--------KPA 340
            +S     SG++  S+   SSPG    ST  +  P++      GE ST            A
Sbjct: 737  ISARSTTSGLVEESTTYHSSPG----STQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 792

Query: 341  PDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNP------PVRATA 394
            P   +      T+  S    T T   P S   S  S +++ S    +       P R+T 
Sbjct: 793  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTN 852

Query: 395  SGVMSAPPVRALDSGAMSTPLM----GAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
            S ++       + SG+M T  +      P     ST   + P S A T S  +  SSGV 
Sbjct: 853  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV- 911

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTS--- 507
             +E+ + + SR  S   T    S   P  S  +        ++ G   T L  A T+   
Sbjct: 912  -SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSH----SSPGSTDTTLLPASTTTXL 966

Query: 508  -GAMSTQPVTATASETMSMPQLTVPAS-GSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             G  +T P+++ ++ET ++P  T  A     S     +P S   ++    T +SG++  +
Sbjct: 967  VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1026

Query: 566  QMKAMTSGAMSTPLMTAQTS---------------GSTSTLLMRDTASGVMSCPQMRSLA 610
                   G+  T      T+               GST T L   + +     P+  +  
Sbjct: 1027 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFH 1086

Query: 611  S--GALSKPLMTPKASGTMFTEKMT----------TTASEAMPTLLMRDTV------SGA 652
            S  G+    L+    + +   E  T          TT S A  T    ++       S  
Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSK 1146

Query: 653  LSMPQMTDTASGGLSASLMRDTASGAMSTSQMTA-TVSGGMSMPLMRAQDPGVMPA---S 708
             +MP    T S  +  S     +  ++ T+  +A + + G S          V PA   S
Sbjct: 1147 DTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPS 1206

Query: 709  LMRAKVSGKMLSQPMSTQDPGG-MSMSPMKSMTAGGMQMNSPTSDVMSTPTVR---AWTS 764
              R+  SG +         PG   +M   +S TA G    S TS   +T T+    + TS
Sbjct: 1207 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1266

Query: 765  ETMSTPLMRTSDPG-----ERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMS 819
              +  P    S PG       P   T +  S E +        +G    P      G ++
Sbjct: 1267 ALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIA 1326

Query: 820  APQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPT 879
                   + G M +     A   G  +      ++S        R+PD  ++  S    +
Sbjct: 1327 ESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS--------RSPDQTLSPASMTSSS 1378

Query: 880  ASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTA 939
             SG+  +L  +A ++   + P      SG         S   +  T L   S +      
Sbjct: 1379 ISGEPTSLYSQAESTHTTAFP-ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQ 1437

Query: 940  QTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSR 999
            + T   S   S     +PAS T+P   +S  ++   S P       G+T T   S +N+ 
Sbjct: 1438 EFTTPHSQPGSALSTVSPASTTVPG--LSEESTTFYSSP-------GSTETTAFSHSNTM 1488

Query: 1000 SMSLSQTT-----YTVSGRMATAPIRASASGARSTSFMRAS-VSGSMPMPLPRATAS 1050
            S+   Q+T        +  +  A +  +  G  ST+F  +S  +G+ P+P  R+TAS
Sbjct: 1489 SIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLP-ARSTAS 1544



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 277/1218 (22%), Positives = 430/1218 (35%), Gaps = 163/1218 (13%)

Query: 54   SASDPGGTSTQLMTSPVFDTMSAP----LMGVPNSGALSPPLMPASDSGALSPLLMPASD 109
            S+SDP  T +    S  F T S      L    NSG      +  S  GA    L P+  
Sbjct: 105  SSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHS 164

Query: 110  SGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAM 169
            + ++       +     SP+ S S      PG  T       S T   +P S + +    
Sbjct: 165  ATSVF------VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPA 218

Query: 170  PAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAM 229
               SSGV  +   +TS S    T  +  PDS  +  +  +       ++  +P  +   +
Sbjct: 219  RTTSSGV--SEKSTTSHSRPGPTHTIAFPDSTTMPGVSQES-----TASHSIPGSTDTTL 271

Query: 230  SPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI--SSLIMSAVASGGTSPQPTS 287
            SP   T       S    ++    + + L  + T S  +  S+ + S+  S  T+  P S
Sbjct: 272  SPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPAS 331

Query: 288  TQNSGGIPTPLM--------SDLDSGIMSSLLM------SSP---------------GSE 318
            +    G PT           S   SG  S+ +       SSP               G  
Sbjct: 332  STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHS 391

Query: 319  VMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQ 378
              STP+ S P A   +T P PA  A +      TA       TQTM  P S   S  S +
Sbjct: 392  EESTPVHSSPVA--TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEE 449

Query: 379  NVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMT 438
            +      S    +++     +A    +  S   ST       S  +S   +   AS +  
Sbjct: 450  SATFH-GSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP 508

Query: 439  TSLMT--VPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGK 496
             ++ T  +P+    S     +T S + S  +      G+     +   +  +  +  S  
Sbjct: 509  DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPD 568

Query: 497  MSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRT 556
             +T L  + TS  +S +  T + S   S      P S +M  L   +  S +   P   T
Sbjct: 569  -TTHLPASMTSSGVSEES-TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 626

Query: 557  MASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRD--TASGVM--SCPQMRSLASG 612
            ++ G T+A+ +    +   S P       GST T L+ D  TASG++  S P   S  S 
Sbjct: 627  LSPGSTTASSLGPEYTTFHSRP-------GSTETTLLPDNTTASGLLEASMPVHSSTRS- 678

Query: 613  ALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMR 672
                P  T   +G+  T +  +T   + P+    DT       P    T S  +  S   
Sbjct: 679  ----PHTTLSPAGST-TRQGESTTFHSWPS--SNDT------RPAPPTTTSAFVEPSTTS 725

Query: 673  DTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMS 732
              +  ++ T+ ++A           R+   G++       + S    S P STQ     +
Sbjct: 726  HGSPSSIPTTHISA-----------RSTTSGLV-------EESTTYHSSPGSTQ-----T 762

Query: 733  MSPMKSMTAGGMQMNSPTSDVMSTPTVR---AWTSETMSTPLMRTSDPGER-----PSLL 784
            M   +S T  G    S TS   +T T+    + TS  +  P    S PG       P   
Sbjct: 763  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 822

Query: 785  TRASSSGEMSLPLMRAPASGEIATPLRS--------PAYGAMSAPQMTATASGMMSSMPQ 836
            T +  S E         A+G I  P RS             +S+  M  TA    ++ P 
Sbjct: 823  TTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPG 882

Query: 837  VKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQ---MMPTASGDMCTLP----- 888
            +    +   S P + +T     S       +   TS S+      TA  D  T P     
Sbjct: 883  LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH 942

Query: 889  -VRAPASGGVSSPLVRAPASGT---MSTPLRRPSACETVSTELMRASASGHMSTAQTTAM 944
               + +S G S+     PAS T   +  P   P +  +  T  +  S +    + ++T  
Sbjct: 943  STTSHSSPG-STDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 1001

Query: 945  VSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRS-MSL 1003
             S   S     +PAS T       +  S         T   G+T+    S  ++ S  S 
Sbjct: 1002 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1061

Query: 1004 SQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTA 1063
              T  T+S R  T    AS+ G  ST+F     S    +     TASG  +  S P  ++
Sbjct: 1062 GSTDTTLSPRSTT----ASSLGPESTTFHSGPGSTETTLLPDNTTASGL-LEASTPVHSS 1116

Query: 1064 TDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTS----HINITASGSK- 1118
            T   G     +  +G  T     T F   S P  K T     +T+     ++ T+ GS  
Sbjct: 1117 T---GSPRTTLSPAGSTTRQGESTTF--QSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1171

Query: 1119 --PTSHMTA-----------TTPETAKPPPKEVPSFGMLTPALCYLLEEQEAARGSCSVE 1165
              PT+H +A           TT  ++   P   PS    T +   L+EE  A   S    
Sbjct: 1172 SIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTS--GLVEESTAYHSSPGST 1229

Query: 1166 EEMEIDEEKQMKGFLDDS 1183
            + M   E     G  ++S
Sbjct: 1230 QTMHFPESSTASGRSEES 1247



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 142/652 (21%), Positives = 240/652 (36%), Gaps = 84/652 (12%)

Query: 52   STSASDPGGTSTQLM-TSPVFDTMSAPLMGVPNSGALSPPLMPASDSGA------LSPLL 104
            +TS S PG T T L+  S     +  P     +SG+     +P S + A       +   
Sbjct: 944  TTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 1003

Query: 105  MPASDSGALSPLLMPAL---DSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDS 161
             P S    LSP    +    +  T S     S +    PG  T+P     S     +P S
Sbjct: 1004 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1063

Query: 162  AE--ISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQD--MNPGVMS 217
             +  +SP +  A S G    P  +T  S   ST   L PD+   S +L     ++    S
Sbjct: 1064 TDTTLSPRSTTASSLG----PESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGS 1119

Query: 218  TQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSL----IM 273
             +   +P+       + T   +   SK  M A  +   + + +S T   + SS+      
Sbjct: 1120 PRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFS 1179

Query: 274  SAVASGGTSPQPTSTQNSGGIPTPLMS---DLDSGIM--SSLLMSSPGSEVMSTPLLSVP 328
            ++  + G S + T+  +S   P    S      SG++  S+   SSPGS    T  +  P
Sbjct: 1180 ASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGS----TQTMHFP 1235

Query: 329  DAGEMSTLPKPAPDAEAMSPALMTALPSGVM-----PTQTMPAPGSGAMSPW-------- 375
            ++   S   + +  + + +   +++ PS        PT    +PGS A + +        
Sbjct: 1236 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSG 1295

Query: 376  -------STQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQ 428
                   S  + D+  ++  P   T SG ++      +  G+M T L     +  +S  +
Sbjct: 1296 RSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSA-K 1354

Query: 429  KTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQY 488
             T+  S + +      P+S  M++  +S   + + S   +   T  A P  +  +   Q 
Sbjct: 1355 STILYSSSRSPDQTLSPAS--MTSSSISGEPTSLYSQAESTHTT--AFPASTTTSGLSQE 1410

Query: 489  KRATASGKMSTPLRRAPTSGAMST----------QPVTATASETMSMPQLTVPASGSMSM 538
                 S   ST    +P S   S+          QP   +A  T+S    TVP     S 
Sbjct: 1411 STTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQP--GSALSTVSPASTTVPGLSEEST 1468

Query: 539  LQMRAPVS-EAMSMPQMRTMA------------SGLTSAAQMKAMTS---GAMSTPLMTA 582
                +P S E  +     TM+             G T       +T+   G  ST   ++
Sbjct: 1469 TFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSS 1528

Query: 583  QTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTT 634
              +  T+ L  R TAS ++  P    ++       L    +S +  TE+ TT
Sbjct: 1529 SDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTT 1580



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 114/503 (22%), Positives = 181/503 (35%), Gaps = 99/503 (19%)

Query: 42   LHSHVQLPIVSTSASDPGGTSTQLMTSPVF-------DTMSAP------LMGVPNSGALS 88
            +HS    P  + S   P G++T+   S  F       DTM AP       + +  +   S
Sbjct: 1113 VHSSTGSPRTTLS---PAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1169

Query: 89   PPLMPASDSGALSPLLMPASDS-----GALSPLLMPALDSGTLSPLLSTSEYGVMSPGM- 142
            P  +P +   A S     + +S       ++P   P+    T S L+  S     SPG  
Sbjct: 1170 PSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGST 1229

Query: 143  --MTIPDFGTMSATLMVAPDSAEISPLAMPAPSS----------------GVVCT---PI 181
              M  P+  T S     +  S   +   + +P S                G + T   P 
Sbjct: 1230 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPE 1289

Query: 182  MSTSSSEAM-STPLMLAPDSGELSPILMQD-------------MNPGVM-----STQPVP 222
             ST+S  +  ST    +PD+  ++P+                 ++PG M     ST   P
Sbjct: 1290 SSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTP 1349

Query: 223  APSSEAMSPLQITDEDTEAMSKVLMTALA-SGEISSLLMSGTDSEAISSLIMSAVASGGT 281
              S+++      +    + +S   MT+ + SGE +SL  S  +S   ++   S   SG +
Sbjct: 1350 GLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLY-SQAESTHTTAFPASTTTSGLS 1408

Query: 282  SPQPTSTQNSGGIPTPLM--SDLDSGIMSSLLM--SSPGSEV--MSTPLLSVPDAGEMST 335
                T     G   T L   S   S          S PGS +  +S    +VP   E ST
Sbjct: 1409 QESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEEST 1468

Query: 336  LPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGS-----------------GAMSPWSTQ 378
                +P +   + A   +    +   Q+ P P S                 G  S     
Sbjct: 1469 TFYSSPGSTETT-AFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHS 1527

Query: 379  NVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMT 438
            + D+   +  P R+TAS ++  P    +      T L   PAS + S L +        +
Sbjct: 1528 SSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLF--PASSSTSGLTEE-------S 1578

Query: 439  TSLMTVPS--SGVMSTEQMSATA 459
            T+  T PS  S ++STE +   A
Sbjct: 1579 TTFHTSPSFTSTIVSTESLETLA 1601


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 253/1252 (20%), Positives = 434/1252 (34%), Gaps = 209/1252 (16%)

Query: 54   SASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL-----LMPAS 108
            S + P  T     T+ V  T +      P+S   +   +P   S   +P      + P+S
Sbjct: 3230 SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSS 3289

Query: 109  DSGAL-SPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATL---MVAPDSAEI 164
              G   +P ++    +   +  ++T      + G    P     +AT     ++P S   
Sbjct: 3290 IPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHT 3349

Query: 165  SPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAP 224
               A  + +SG + T  ++  S+    TP      +   +P L    +P   +T+  P+P
Sbjct: 3350 VRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP-HPSSRTTESPPSP 3408

Query: 225  SSEAMSPLQITDEDTEAM-------SKVLMTALASGEISSLLMSGTDSEAISSLIMS--- 274
             +      + T   T          S +L ++  S  I++++  G + +   S  +    
Sbjct: 3409 GTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 3468

Query: 275  ----------------AVASGGTSPQPTS----TQNSGGIPTPLMSD-----LDSGIMS- 308
                              A G    QP       Q   G+P   +       LD G++  
Sbjct: 3469 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 3528

Query: 309  -----------------------SLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEA 345
                                       S+P +   +TP  S P  G    L +    A  
Sbjct: 3529 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPS-STP--GTTWILTEQTTAATT 3585

Query: 346  MSPALMTALPSGVMPTQTMP------APGSGAMSPWSTQNVDSEMMSNPPV---RATASG 396
             +    TA+PS    T   P      A    A S  +T +      +  PV    AT S 
Sbjct: 3586 TATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKST 3645

Query: 397  VMSAPPVRALDSGAMST-PLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQM 455
              S  P+ +   G   T P         MST+  +       T++++T  ++   +T  M
Sbjct: 3646 ATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSM 3705

Query: 456  SATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPV 515
            S  +S   +  +    T+ A  T +    A       +S   +T +   P++ A  T P 
Sbjct: 3706 STPSSTPGTTWILTELTTAATTTAATGPTA-----TPSSTPGTTWILTEPSTTATVTVPT 3760

Query: 516  --TATASETMS----MPQLTVPASGSMSMLQMRAPVSE---AMSMPQMRTMASGLTSAAQ 566
              TATAS T +    +  LT  A+    +     P S    A ++P +R+ A+  T A  
Sbjct: 3761 GSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPT-ATS 3819

Query: 567  MKAMTSGAM----------STPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSK 616
            + A+ S ++          +TP  T  T+  +ST     T++ V++     + A+G+++ 
Sbjct: 3820 VTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTST-VLTTTTTTTRATGSVAT 3878

Query: 617  PLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLS---ASLMRD 673
            P  TP  + T      TTT   A P+      ++  + +   T   + G +   +S+   
Sbjct: 3879 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 3938

Query: 674  TASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM 733
            T +  + T+  T   +G M+ P    Q  G      +           P +T    G S+
Sbjct: 3939 THTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV-----------PNTTATTHGRSL 3987

Query: 734  SPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEM 793
             P    T       S TS ++ T  +   ++ T  TP   TS         T A SS   
Sbjct: 3988 PPSSPHTV-RTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHS----TPALSSPHP 4042

Query: 794  SLPLMRAPASGEIATPLRSPAYG---AMSAPQMTATASGMMSSMPQVKAPISGAMSMPLT 850
            S     +P S    TP  +       A + P  T T++ + SS     API+  ++    
Sbjct: 4043 SSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSS--PTSAPITTVVTTGCE 4100

Query: 851  RSTASG---GMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPV----RAPASGGVS----- 898
               A       S P M  P      T   +  A G +C  P+    RA A  GV      
Sbjct: 4101 PQCAWSEWLDYSYP-MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELG 4159

Query: 899  -------------------------------------SPLVRAPASGTMSTPLRRPSACE 921
                                                       PA+ + +TP   P    
Sbjct: 4160 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGT-T 4218

Query: 922  TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME 981
             + T+L   + +   + +  T   + G +  L     + T+ +P  S   +         
Sbjct: 4219 WILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS-------S 4271

Query: 982  TMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAP-IRASASGARSTSF--MRASVSG 1038
            T A+  T  + T+       S   T ++  G     P +R++A+   +TSF  + +S  G
Sbjct: 4272 TQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLG 4331

Query: 1039 SMPMPLPRATASGCGMGMSMPQM---TATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
            +    L + T     M  + P     TA  S  ++T        G+++TP +  G   T 
Sbjct: 4332 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTT 4391

Query: 1096 EIKATDSGEASTSHINITASGSKPTSH------MTATTPET--AKPPPKEVP 1139
            ++  T     +T+   +T S S  T+        T TTP T  +   P  VP
Sbjct: 4392 KVPTT-----TTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVP 4438



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 230/1084 (21%), Positives = 392/1084 (36%), Gaps = 146/1084 (13%)

Query: 52   STSASDPGGT-------STQLMTSPVFDTMSAP----LMGVPNSGALSPPLMPASDSGAL 100
            +T +S PG T       +T  +T P   T +A       G P+    +    P   S   
Sbjct: 3091 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT--PTVTSSKA 3148

Query: 101  SPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
            +P   P + +       +PAL S   +P  +TS   + S  + T     + + T      
Sbjct: 3149 TPFSSPGTATA------LPALRSTATTPT-ATSFTAIPSSSLGTTWTRLSQTTTPTATMS 3201

Query: 161  SAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQP 220
            +A  S       +S V+ T   +T ++ +++TP    P +   + +L      G  +T P
Sbjct: 3202 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSS-TPGTAHTTKVLTTTTT-GFTAT-P 3258

Query: 221  VPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
              +P +    P+ I+   T        T   S    S +   T +  + +   + VA+G 
Sbjct: 3259 SSSPGTARTLPVWISTTTTP-------TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS 3311

Query: 281  TSPQPTSTQNSGGIPTPLMSDLDSGIMS-SLLMSSPG----------SEVMSTPLLSVPD 329
             +   +STQ SG   TP + +  +     SL  SSP           S  + T  ++ P 
Sbjct: 3312 MATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPS 3371

Query: 330  AGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPP 389
             G   T        +  +PAL +  PS    T++ P+PG+   +P  T+       +  P
Sbjct: 3372 TGTSHTPAATTGTTQHSTPALSSPHPSS-RTTESPPSPGT--TTPGHTRATSRTTATATP 3428

Query: 390  VRATASGVM-----SAPPVRALDSGA-----------MSTPLMGAPASGNMSTLQKTVPA 433
             +   S ++     SAP    +  G             S P+ G P+ G+  T      A
Sbjct: 3429 SKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPG-PSGGDFDTYSNIRAA 3487

Query: 434  SGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTS-GAMPTGSMKAVAKQYKRA- 491
             GA+    + +                +V+   L            G  K       R  
Sbjct: 3488 GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 3547

Query: 492  ----------TASGKMSTPLRRAPTSGAMSTQPVTATASETM---SMPQLTVPASGSMSM 538
                       A+   +TP     T+  ++ Q   AT + T    ++P  T   +    +
Sbjct: 3548 CCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKV 3607

Query: 539  LQMRAPVSEAMSM-------PQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTL 591
            L   A    A S        P+  T    LTS A     TS    TP+ +  T G+T TL
Sbjct: 3608 LTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS---FTPIPSF-TLGTTGTL 3663

Query: 592  LMRDTAS-GVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVS 650
              + T     MS     S      +  ++T KA+ T  T  M+T +S    T ++ +  +
Sbjct: 3664 PEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTT 3723

Query: 651  GALSM----PQMTDTASGGLSASLMRDTAS-------GAMSTSQMTATVSGGMSMPLMRA 699
             A +     P  T +++ G +  L   + +       G+ +T+  T   +G + +    A
Sbjct: 3724 AATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTA 3783

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
              P V+              S+   +  PG  +  P    TA      S T+ + S+   
Sbjct: 3784 TTPTVIS-------------SRATPSSSPGTATALPALRSTATTPTATSVTA-IPSSSLG 3829

Query: 760  RAWT---SETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYG 816
             AWT     T  T  M T+ P   P  +    +S  ++       A+G +ATP  +P  G
Sbjct: 3830 TAWTRLSQTTTPTATMSTATPSSTPETV---HTSTVLTTTTTTTRATGSVATPSSTP--G 3884

Query: 817  AMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQM 876
                 ++  T +   ++ P        A++ P+  ST +     P  R   S VT +S  
Sbjct: 3885 TAHTTKVPTTTTTGFTATPSSSP--GTALTPPVWISTTT----TPTTRG--STVTPSSIP 3936

Query: 877  MPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHM 936
              T +  + T      A+G +++P      SGT  TP   P+   T     +  S+   +
Sbjct: 3937 GTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP-PVPNTTATTHGRSLPPSSPHTV 3995

Query: 937  STAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGAT-----STL 991
             TA T+A  SG +    +  P++ T   P  +   +   +  L     S  T     S  
Sbjct: 3996 RTAWTSA-TSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPG 4054

Query: 992  QTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS----------VSGSMP 1041
             T+  ++R  S +  T T S    +  + +S + A  T+ +             +  S P
Sbjct: 4055 TTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP 4114

Query: 1042 MPLP 1045
            MP P
Sbjct: 4115 MPGP 4118



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 231/1104 (20%), Positives = 394/1104 (35%), Gaps = 126/1104 (11%)

Query: 52   STSASDPGGT-------STQLMTSPVFDTMSAP----LMGVPNSGALSPPLMPASDSGAL 100
            +T +S PG T       +T  +T P   T +A       G P+    +    P   S   
Sbjct: 4238 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT--PTVTSSKA 4295

Query: 101  SPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
            +P   P + +       +PAL S   +P  +TS   + S  + T     + + T      
Sbjct: 4296 TPFSSPGTATA------LPALRSTATTPT-ATSFTAIPSSSLGTTWTRLSQTTTPTATMS 4348

Query: 161  SAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQP 220
            +A  S     A +S V+ T   +T ++ +++TP   +   G      +        +  P
Sbjct: 4349 TATPSSTPETAHTSTVLTTTATTTRATGSVATP---SSTPGTAHTTKVPTTTTTGFTVTP 4405

Query: 221  VPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
              +P +    P+ I+   T   S   +T        S +   T +  + +   + VA+G 
Sbjct: 4406 SSSPGTARTPPVWISTTTTPTTSGSTVTP-------SSVPGTTHTPTVLTTTTTTVATGS 4458

Query: 281  TSPQPTSTQNSGGIPTPLMSDLDSGIMS-SLLMSSP----------GSEVMSTPLLSVPD 329
             +   +STQ SG   TP + +  +     SL  SSP           S  + T  ++ P 
Sbjct: 4459 MATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPS 4518

Query: 330  AGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPP 389
             G   T        +  +PAL +  PS    T++ P+PG+   +P  T        +  P
Sbjct: 4519 TGTSHTPAATTGTTQHSTPALSSPHPSS-RTTESPPSPGT--TTPGHTTATSRTTATATP 4575

Query: 390  VRATASGVMSAPPVRALDSGAMSTPL---------------MGAPASGNMSTLQKTVPAS 434
             +   S ++ + P  A  +  ++T                 M  P+ G+  T      A 
Sbjct: 4576 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 4635

Query: 435  GAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKT-SGAMPTGSMKAVAKQYKRATA 493
            GA+    + +                +V+   L            G  K       R   
Sbjct: 4636 GAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 4695

Query: 494  SGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQ 553
                  P   A +S AM     ++T   T  + +LT  A+ + S      P S   + P 
Sbjct: 4696 CNYGHCPSTPATSSTAMP----SSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPP 4751

Query: 554  MRTMASGLT--SAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLAS 611
             + + S  T  +A   KA +S   S+P  TA T    ++   + TA+ V   P      +
Sbjct: 4752 PKVLTSPATTPTATSSKATSS---SSP-RTATTLPVLTSTATKSTATSVTPIPSSTLGTT 4807

Query: 612  GALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLM 671
            G L +   TP A+ +      T   +     L  + T + A S    T +++ G +  L 
Sbjct: 4808 GTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTS-TPSSTPGTTWILT 4866

Query: 672  RDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGM 731
                   ++T+  T   +G  + P        ++      A  +    S    +  PG  
Sbjct: 4867 E------LTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTT 4920

Query: 732  SMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRT--SDPGERPSLLTRASS 789
             +    S TA    +  PT    ST T  + T  T  TP + T  + P    S  T +SS
Sbjct: 4921 WILTEPSTTA---TVTVPTG---STATASS-TQATAGTPHVSTTATTPTVTSSKATPSSS 4973

Query: 790  SG-EMSLPLMRAPASGEIATPLRSPAYGAMSAP----QMTATASGMMSSMPQVKAPISGA 844
             G   +LP +R+ A+   AT   +    ++         T T +  MS+      P +  
Sbjct: 4974 PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH 5033

Query: 845  MSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRA 904
             S  LT +  + G +  +     +  T+ +  +PT +    T    +     ++ P    
Sbjct: 5034 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPP---- 5089

Query: 905  PASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMP- 963
                  +TP+   S   T ST       + H ST  TT       +  + RA  S   P 
Sbjct: 5090 -----TTTPMSTMSTIHTSST-----PETTHTSTVLTT-------TATMTRATNSTATPS 5132

Query: 964  MPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASA 1023
              L +     E++     T A+G+T+TL ++   +  ++   T  TV   M      A+A
Sbjct: 5133 STLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATV---MVPTGSTATA 5189

Query: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMS 1083
            S    T+     V+    M  P ATAS      ++P  +   +    TP +  S   T S
Sbjct: 5190 SSTLGTAHTPKVVTTMATM--PTATAS------TVPSSSTVGT--TRTPAVLPSSLPTFS 5239

Query: 1084 TPQTAFGVMSTPEIKATDSGEAST 1107
                +  V++T       S   ST
Sbjct: 5240 VSTVSSSVLTTLRPTGFPSSHFST 5263



 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 260/1286 (20%), Positives = 450/1286 (34%), Gaps = 232/1286 (18%)

Query: 43   HSHVQLPIVSTSASDPGGT--STQLMTSPVFD---TMSAPLMGVPNSGALSPPLMPASDS 97
            +SH      ++S + P  T  +T ++T P      T S      P S   + P      +
Sbjct: 2575 YSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 2634

Query: 98   GALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMV 157
             A +P +  +  + + SP       + T  P L ++     +  +  IP     +    +
Sbjct: 2635 TATTPTVTSSKATPSSSP------GTATALPALRSTATTPTATSVTPIPSSSLGTTWTRL 2688

Query: 158  APDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMS 217
            +  +   + ++   PSS    TP  + +S+   +T    A  +G    +      PG   
Sbjct: 2689 SQTTTPTATMSTATPSS----TPETAHTSTVLTAT----ATTTGATGSVATPSSTPGTAH 2740

Query: 218  TQPVPAPSSEAMSPLQITDEDTEAMSKVLM------TALASGEISSLLMSGTDSEAISSL 271
            T  VP  ++   +    +   T     V +      T   S    S +   T +  + + 
Sbjct: 2741 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 2800

Query: 272  IMSAVASGGTSPQPTSTQNSGGIPT-PLMSDLDSGIMSSLLMSSP----------GSEVM 320
              + VA+G  +   +STQ SG   T P+ + + +    SL  SSP           S ++
Sbjct: 2801 TTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGIL 2860

Query: 321  STPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNV 380
             T  ++ P      TL       +  +PAL +  PS    T++ P+PG+   +P  T   
Sbjct: 2861 GTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSS-RTTESPPSPGT--TTPGHTTAT 2917

Query: 381  DSEMMSNPPVRATASGVM-----SAPPVRALDSGA-----------MSTPLMGAPASGNM 424
                 +  P +   S ++     SAP    +  G             S P+ G P+ G+ 
Sbjct: 2918 SRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPG-PSGGDF 2976

Query: 425  STLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL----------------- 467
             T      A GA+    + +                +V+   L                 
Sbjct: 2977 DTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKM 3036

Query: 468  ------------------TMAKTSGAMPT---GSMKAVAKQYKRAT---ASGKMSTP--- 500
                              T A +S AMP+   G+   + +    AT   ++G  +TP   
Sbjct: 3037 CFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSST 3096

Query: 501  -----LRRAPTSGAMSTQPV--TATASETMS---MPQLTVPASGSMSMLQMRAPVSE--- 547
                 +   P++ A  T P   TATAS T +    P ++  A+          P S    
Sbjct: 3097 PGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 3156

Query: 548  AMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTA--------SG 599
            A ++P +R+ A+  T+ +     +S   +T    +QT+  T+T+     +        S 
Sbjct: 3157 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST 3216

Query: 600  VMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMP--- 656
            V++     + A+G+++ P  TP   GT  T K+ TT +    T     +   A ++P   
Sbjct: 3217 VLTTTATTTGATGSVATPSSTP---GTAHTTKVLTTTTTGF-TATPSSSPGTARTLPVWI 3272

Query: 657  --QMTDTASGG--LSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVM---PASL 709
                T T  G     +S+   T +  + T+  T   +G M+ P    Q  G     P   
Sbjct: 3273 STTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPN 3332

Query: 710  MRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMST 769
              A   G+ LS   S+      + +   S T G   +  P++    TP     T++  ST
Sbjct: 3333 TTATTHGRSLSP--SSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQ-HST 3389

Query: 770  PLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYG---AMSAPQMTAT 826
            P + +  P  R +                 +P S    TP  + A     A + P  T T
Sbjct: 3390 PALSSPHPSSRTT----------------ESPPSPGTTTPGHTRATSRTTATATPSKTRT 3433

Query: 827  ASGMMSSMPQVKAPISGAMSMPLTRSTASG---GMSMPLMRAPDSRVTSTSQMMPTASGD 883
            ++ + SS     API+  ++M      A       S P M  P      T   +  A G 
Sbjct: 3434 STLLPSS--PTSAPITTVVTMGCEPQCAWSEWLDYSYP-MPGPSGGDFDTYSNIRAAGGA 3490

Query: 884  MCTLPV----RAPASGGVS----------------------------------------- 898
            +C  P+    RA A  GV                                          
Sbjct: 3491 VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCN 3550

Query: 899  -SPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSG--GMSKPLMR 955
                   PA+ + +TP   P     ++ +   A+ +   +T  +TA+ S   G + P   
Sbjct: 3551 YGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTT---ATTGSTAIPSSTPGTAPPPKV 3607

Query: 956  APASGTMPMPLMS--AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGR 1013
              ++ T P    S    +S   +   +  + S AT +  TS     S +L  TT T+  +
Sbjct: 3608 LTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLG-TTGTLPEQ 3666

Query: 1014 MATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDS---RGMS 1070
              T     S     ST       + +  +   +AT +     MS P  T   +     ++
Sbjct: 3667 TTTPMATMSTIHPSST----PETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELT 3722

Query: 1071 TPLMRASGPGTMSTPQTAFG---VMSTPEIKAT---DSGEASTSHINITASGSKPTSHMT 1124
            T     +  G  +TP +  G   +++ P   AT    +G  +T+      +G+      T
Sbjct: 3723 TAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTST 3782

Query: 1125 ATTPE--TAKPPPKEVPSFGMLTPAL 1148
            ATTP   +++  P   P      PAL
Sbjct: 3783 ATTPTVISSRATPSSSPGTATALPAL 3808



 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 230/1144 (20%), Positives = 393/1144 (34%), Gaps = 138/1144 (12%)

Query: 67   TSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTL 126
            ++P   + + P      +  L+     A+ + +      P+S  G    L  P+  +   
Sbjct: 4201 STPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT 4260

Query: 127  SPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSS 186
             P  ST+          T P   T + T  V   S++ +P + P  ++ +   P + +++
Sbjct: 4261 VPTGSTATASSTQATAGT-PHVSTTATTPTVT--SSKATPFSSPGTATAL---PALRSTA 4314

Query: 187  SEAMSTPLMLAPDS--GELSPILMQDMNPGVMSTQPVPAPSSEAM---SPLQITDEDTEA 241
            +   +T     P S  G     L Q   P    +   P+ + E     + L  T   T A
Sbjct: 4315 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRA 4374

Query: 242  MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSP----QPTSTQNSGGIPTP 297
               V   +   G   +  +  T +   +    S+  +  T P      T+   SG   TP
Sbjct: 4375 TGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTP 4434

Query: 298  LMSDLDSGIMSSLLMSSPGSEV----MSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA 353
              S +     +  ++++  + V    M+TP  S   +G   T P P   A     +L  +
Sbjct: 4435 --SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPS 4492

Query: 354  LPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMST 413
             P  V    T    G+               +    +   ++G  S  P     +   ST
Sbjct: 4493 SPHTVRTAWTSATSGT---------------LGTTHITEPSTGT-SHTPAATTGTTQHST 4536

Query: 414  PLMGAPASGNMSTLQKTVPAS---GAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMA 470
            P + +P   + +T     P +   G  T +  T  ++    T   +   S   SA +T  
Sbjct: 4537 PALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 4596

Query: 471  KTSGAMPTGSMKA-VAKQYKRATASG-KMSTPLRRAPTSGAMSTQPV----TATASETMS 524
             T+G  P  +    +   Y     SG    T        GA+  QP+     A A   + 
Sbjct: 4597 VTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 4656

Query: 525  MPQLTVPASGSMS---MLQMRAPVSEAMSM--PQMRTMASGLTSAAQMKAMTSGAM--ST 577
            + +L      S+    + + R  V +       ++R             A +S AM  ST
Sbjct: 4657 LGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 4716

Query: 578  P---------LMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
            P           TA T+ ST +     +  G    P++       L+ P  TP A+ +  
Sbjct: 4717 PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKV-------LTSPATTPTATSSKA 4769

Query: 629  TEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTAS--GAMSTSQMTA 686
            T   +   +  +P L    T S A S+  +  +  G  + +L   T +    MST   ++
Sbjct: 4770 TSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLG-TTGTLPEQTTTPVATMSTIHPSS 4828

Query: 687  TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQM 746
            T     +  ++  +      A+  RA  S    S P ST  PG   +    +  A     
Sbjct: 4829 TPETTHTSTVLTTK------ATTTRATSS---TSTPSST--PGTTWILTELTTAATTTAA 4877

Query: 747  NSPTSDVMSTPTVRAW------TSETMSTPLMRTSDPGERPS---LLTRASSSGEMSLPL 797
              PT+   STP    W      T+ T +     T+ P   P    +LT  S++  +++P 
Sbjct: 4878 TGPTATPSSTPGT-TWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVP- 4935

Query: 798  MRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGG 857
                 +G  AT   + A         TAT   + SS     +    A ++P  RSTA+  
Sbjct: 4936 -----TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTP 4990

Query: 858  MSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGG--------VSSPLVRAPASGT 909
             +      P S + +T   +   +    T+    P+S          +++      A+G+
Sbjct: 4991 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGS 5050

Query: 910  MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSA 969
            ++TP   P    T             + T  TT   +   S P        T PM  MS 
Sbjct: 5051 VATPSSTPGTAHTTK-----------VPTTTTTGFTATPSSSPGTALTPPTTTPMSTMST 5099

Query: 970  MASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARST 1029
            + +         T  +  TST+ T+ A       + +T T S  + T  I    +   +T
Sbjct: 5100 IHTS-------STPETTHTSTVLTTTAT--MTRATNSTATPSSTLGTTRILTELTTTATT 5150

Query: 1030 SFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAF 1089
            +    S +     P       G    ++ P   AT      +    +S  GT  TP+   
Sbjct: 5151 TAATGSTATLSSTP-------GTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVT 5203

Query: 1090 GVMSTPEIKAT---DSGEASTSHINITASGSKPT-SHMTATTPETAKPPPKEVPSFGMLT 1145
             + + P   A+    S    T+        S PT S  T ++       P   PS    T
Sbjct: 5204 TMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFST 5263

Query: 1146 PALC 1149
            P  C
Sbjct: 5264 PCFC 5267



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 211/1008 (20%), Positives = 368/1008 (36%), Gaps = 124/1008 (12%)

Query: 2    SIPLHSLRFNNTMREENVEPQNKQMAFCRPMT--ETRADVQILHSHVQLPIVSTSASDPG 59
            +IP  SL    T   +   P    M+   P +  ET     +L +       + S + P 
Sbjct: 4324 AIPSSSLGTTWTRLSQTTTP-TATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPS 4382

Query: 60   GTSTQLMTSPVFDTMSAPLMGVPNSG---ALSPPLMPASDSGALSPLLMPASDSGALSPL 116
             T     T+ V  T +      P+S    A +PP+        +S    P +    ++P 
Sbjct: 4383 STPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVW-------ISTTTTPTTSGSTVTPS 4435

Query: 117  LMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLM---VAPDSAEISPLAMPAPS 173
             +P     T +P + T+    ++ G M  P   T ++        P++   +     +PS
Sbjct: 4436 SVPGT---THTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPS 4492

Query: 174  SGVVCTPIMSTSSSEAMSTPLMLAPDSGE-----LSPILMQDMNPGVMSTQPVPAPSSEA 228
            S        ++++S  + T  +  P +G       +    Q   P + S  P    +   
Sbjct: 4493 SPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESP 4552

Query: 229  MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTST 288
             SP   T   T A S+   TA  S   +S L+  + + A     ++ V + G  PQ   +
Sbjct: 4553 PSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAP----ITTVVTTGCEPQCAWS 4608

Query: 289  Q---NSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEA 345
            +    S  +P P   D D+   S++   + G  V   PL       E     +P      
Sbjct: 4609 EWLDYSYPMPGPSGGDFDT--YSNI--RAAGGAVCEQPL-----GLECRAQAQPGVPLGE 4659

Query: 346  MSPALMTALPSGVMPTQ--------------------------TMPAPGSGAMSPWSTQN 379
            +   +  +L  G++                             + PA  S AM P ST  
Sbjct: 4660 LGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM-PSSTPG 4718

Query: 380  VDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTT 439
                +        T +   S     +    A    ++ +PA+   +T  K   +S   T 
Sbjct: 4719 TTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTA 4778

Query: 440  SLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMST 499
            +  T+P   V+++    +TA+ V     +   T+G +P  +   VA       +S   +T
Sbjct: 4779 T--TLP---VLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETT 4833

Query: 500  PLRRAPTSGAMSTQPVTATASE------TMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQ 553
                  T+ A +T+  ++T++       T  + +LT  A+ + +      P +   S P 
Sbjct: 4834 HTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAA----TGPTATPSSTPG 4889

Query: 554  MRTMASGLTSAAQMKAMTSGAMSTPLMTAQTS-----GSTSTLLMRDTASGVMSCPQMRS 608
               + + LT+ A   A T G+ +TP  T  T+      ST+  +   T S   +     +
Sbjct: 4890 TTWILTELTTTATTTAST-GSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQAT 4948

Query: 609  LASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSA 668
              +  +S    TP  + +  T   +   + A+P L    T   A S   +  ++ G    
Sbjct: 4949 AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT 5008

Query: 669  SLMRDTA-SGAMSTSQMTATVSGGMSMPLM--RAQDPGVMPASLMRAKVSGKMLSQPMST 725
             L + T  +  MST+  ++T     +  ++   A   G   +    +   G   +  + T
Sbjct: 5009 RLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 5068

Query: 726  QDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTP-LMRTSDPGERPSLL 784
                G + +P  S    G  +  PT+  MST +    T  T STP    TS      + +
Sbjct: 5069 TTTTGFTATPSSS---PGTALTPPTTTPMSTMS----TIHTSSTPETTHTSTVLTTTATM 5121

Query: 785  TRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGA 844
            TRA++S       +    +  I T L + A    +A   TAT S    +   +  P + A
Sbjct: 5122 TRATNSTATPSSTL---GTTRILTELTTTA-TTTAATGSTATLSSTPGTTWILTEPSTIA 5177

Query: 845  MSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRA 904
              M  T STA+   ++     P  +V +T   MPTA+          P+S  V       
Sbjct: 5178 TVMVPTGSTATASSTLGTAHTP--KVVTTMATMPTATAS------TVPSSSTV------- 5222

Query: 905  PASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKP 952
               GT  TP   PS+  T S   + +S    ++T + T   S   S P
Sbjct: 5223 ---GTTRTPAVLPSSLPTFSVSTVSSSV---LTTLRPTGFPSSHFSTP 5264



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 157/694 (22%), Positives = 250/694 (36%), Gaps = 75/694 (10%)

Query: 401  PPVRALDSGAMSTP--LMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSAT 458
            PP   L++   +T   L   P   +   L +  PAS   TT++ T+ S G+ S    S  
Sbjct: 2304 PPTTELETATTTTTQALFSTPQPTSSPGLTRAPPAS---TTAVPTL-SEGLTSPRYTSTL 2359

Query: 459  ASRVMSAQLTMA-KTSGAMPTGSMKAVAKQYKRATASGKMST-----PLRRAPTSGAMST 512
             +       T A  T   +P  +   +  +      +G + T     P   APT+ A S 
Sbjct: 2360 GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSR 2419

Query: 513  QPVTATASETMSMPQL-----TVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQM 567
               T TAS     P       T+ +  S S  +   P +E    P   T  S  T+  Q 
Sbjct: 2420 ARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQP 2479

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTM 627
            K   +        T+  +G          A+G   C   +S+   A + P ++    G +
Sbjct: 2480 KCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQV 2539

Query: 628  FTEKMTT--TASEAMPT------------LLMRDTVSGALSMPQMTDTASGGLSASLMRD 673
             T  + T  T      T            +L  D  S   S P  + TA+    +S    
Sbjct: 2540 LTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTAT---PSSTPGT 2596

Query: 674  TASGAMSTSQMTATVSGGM----SMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPG 729
            T      T+  T T S G     +  L  A  P V+  +     V+    S+   +  PG
Sbjct: 2597 TWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTS---SKATPSSSPG 2653

Query: 730  GMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWT---SETMSTPLMRTSDPGERPSLLTR 786
              +  P    TA      S T  + S+     WT     T  T  M T+ P   P     
Sbjct: 2654 TATALPALRSTATTPTATSVT-PIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE---T 2709

Query: 787  ASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMS 846
            A +S  ++       A+G +ATP  +P  G     ++  T +   ++ P   +    A++
Sbjct: 2710 AHTSTVLTATATTTGATGSVATPSSTP--GTAHTTKVPTTTTTGFTATP--SSSPGTALT 2765

Query: 847  MPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPA 906
             P+  ST     + P  R   S VT +S    T +  + T      A+G +++P      
Sbjct: 2766 PPVWISTT----TTPTTRG--STVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 2819

Query: 907  SGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT----- 961
            SGT  TP   P+   T     +  S+   + TA T+A  SG +    +  P++ T     
Sbjct: 2820 SGTTHTP-PVPNTMATTHGRSLPPSSPHTVRTAWTSA-TSGILGTTHITEPSTVTSHTLA 2877

Query: 962  ----MPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSM-----SLSQTTYTVSG 1012
                       A++S   S    E+  S  T+T   + A SR+      S ++T+  +  
Sbjct: 2878 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 2937

Query: 1013 RMATAPIRASAS-GARSTSFMRASVSGSMPMPLP 1045
               +API    + G          +  S PMP P
Sbjct: 2938 SPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGP 2971


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 169/702 (24%), Positives = 280/702 (39%), Gaps = 91/702 (12%)

Query: 478  TGSMKAVAKQYKRATASGKMSTP-LRRAPTSGAMSTQPVTATASETMSMPQLTV-PASGS 535
            T S  ++     RA+ +G  ST  L   P+  +++  P  A+   T SM  L V P+  S
Sbjct: 16   TPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSRAS 75

Query: 536  MSMLQMRAPVSEAMSMPQMRTM------ASGLTSAAQMKAMTSGAMSTPLMTAQ--TSGS 587
            ++ +Q  + ++   SM  ++ M         L  A+ M+  ++ +++     A   T+ S
Sbjct: 76   LTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPS 135

Query: 588  TSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF--TEKMTTTASEAMPTLLM 645
             ++L M  + +  ++ P   SL           P+AS TM   T  +T T   A PT + 
Sbjct: 136  RASLSMTPSTAAALTMPSRASLTR-------TPPRASLTMTPSTASLTRTPPRASPTGMP 188

Query: 646  RDT----VSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT-----ATVSGGMSMPL 696
              T    +    S+ +M  TAS  ++ +L R + +G    +  T     A++S   S  L
Sbjct: 189  SRTSPTGMPSTASLTKMDSTAS--ITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTAL 246

Query: 697  MRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM-SPMKSMTAGGMQMNSPTSDVM- 754
            +    P   P  ++      KM S    T+ P   S  SP  + +   + M   T+ +M 
Sbjct: 247  LIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMR 306

Query: 755  ----STPT-VRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPA-SGEIAT 808
                ++PT + + TS T        S    R S+    S +     P   +P  +   A+
Sbjct: 307  MLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRAS 366

Query: 809  PLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDS 868
            P  SP+  +++    TA+ +G          P + +++    R++ +G +S         
Sbjct: 367  PTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSR-------- 418

Query: 869  RVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELM 928
              TS ++M  TAS      P R P     +    RA  +GT S    R S   T ST   
Sbjct: 419  --TSITKMDSTAS------PTRTPPRASPTGTPPRASPTGTPS----RASPTGTQST--- 463

Query: 929  RASASGHMSTAQ-----TTAMVSGGMSK-PLMRAP--ASGTMPMPLMSAMASGEMSMPLM 980
             AS +G  STA      +TA  +G  S+  L R P  AS T      S   +   + P  
Sbjct: 464  -ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTW 522

Query: 981  ETMASGATSTLQTSVAN--------SRSMSLSQTTYTVSGRMATAPIRASASGARSTSFM 1032
                +  T +  T++A         +R+ S +  T T S    T P RAS +   ST  +
Sbjct: 523  TPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLL 582

Query: 1033 RASVSGSMPMPLP-RATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGV 1091
                  + P  +P R + +G      + +M +T S   + P  RAS      TP  A   
Sbjct: 583  TRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPP--RAS---PTETPPRASPT 637

Query: 1092 MSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
             + P  +A+ +G    +    T   + PT      TP  A P
Sbjct: 638  GTPP--RASPTGTPPRASPTGTPPRASPTG-----TPSRASP 672



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 157/657 (23%), Positives = 264/657 (40%), Gaps = 125/657 (19%)

Query: 500  PLRRAPTSGAMSTQPVTATASETMSMPQLT-VPASGSMSMLQMRAPVSEAMSMPQMRTMA 558
            P  R P+  + +  P TA+ + T S   LT  P++ S+    M  P   +++    R   
Sbjct: 3    PPTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASL----MGTPSRASLTGTPPRASL 58

Query: 559  SGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS-----CPQMRSLASGA 613
             G TS A +       M +P   + T   +S+LL R  +   +        + R+L   +
Sbjct: 59   KGTTSMASL-------MVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRAS 111

Query: 614  LSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRD 673
            L +   T   + +     +TTT S A  +L M  + + AL+MP           ASL   
Sbjct: 112  LMRRPSTASLTRSPSRASLTTTPSRA--SLSMTPSTAAALTMPSRASLTRTPPRASLTMT 169

Query: 674  TASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKV-SGKMLSQPMSTQDPGGMS 732
             ++ +++ +   A+ +G   MP   +  P  MP++    K+ S   +++ +S   P G  
Sbjct: 170  PSTASLTRTPPRASPTG---MPSRTS--PTGMPSTASLTKMDSTASITRTLSRASPTG-- 222

Query: 733  MSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPS-LLTRAS-SS 790
             +P ++         SPT    S P  RA  S   ST L+  + P   P+ +L+R S + 
Sbjct: 223  -TPPRA---------SPTG---SPP--RASLSMMPSTALLIRTPPRASPTGMLSRTSLTK 267

Query: 791  GEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLT 850
             + +  + R P+    A+P  +P+  ++S   MT + + +M  +P               
Sbjct: 268  MDSTASITRTPSRPSTASPTGTPSRASLS---MTPSTASLMRMLP--------------- 309

Query: 851  RSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM 910
            R++ +G +S   +   DS   S S+  P AS                   + R P+    
Sbjct: 310  RASPTGMLSRTSLTKMDS-TASISRTPPRAS-------------------ITRTPSR--- 346

Query: 911  STPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAM 970
            ++P  +PS      T   RAS +G  STA  T + S         A  +GT P     A 
Sbjct: 347  ASPTGKPSTASPTGTP-SRASPTGSPSTASLTGLSS--------TASPTGTPPR----AS 393

Query: 971  ASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTS 1030
             +G  S          A+ T +   A+   M LS+T+ T         + ++AS  R+  
Sbjct: 394  PTGTPST---------ASLTRKPPRASPTGM-LSRTSIT--------KMDSTASPTRTPP 435

Query: 1031 FMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFG 1090
              RAS +G+ P   P  T S      +    + T S   ++P    S      +P  A  
Sbjct: 436  --RASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRA-S 492

Query: 1091 VMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPA 1147
            +  TP  +A+ +   ST+ I  T S + PT      TP TA P      +  M +P+
Sbjct: 493  LTRTPS-RASLTKMESTASITRTPSRASPT-----WTPSTASPTGSPSTALAMGSPS 543



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 158/696 (22%), Positives = 271/696 (38%), Gaps = 66/696 (9%)

Query: 149 GTMS-ATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPIL 207
           GT S A+L   P +A +  +  P+ +S     P  S   + +M++ LM++P    L+   
Sbjct: 24  GTPSRASLTGTPSTASL--MGTPSRASLTGTPPRASLKGTTSMAS-LMVSPSRASLTR-- 78

Query: 208 MQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEA 267
              M    + T+     S + M P           S +   + AS   S    S T + +
Sbjct: 79  ---MQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPS 135

Query: 268 ISSLIMS-AVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLS 326
            +SL M+ + A+  T P   S   +    +  M+   + +  +   +SP      T    
Sbjct: 136 RASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTG 195

Query: 327 VPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
           +P    ++ +   A     +S A  T  P    PT + P   S +M P       + ++ 
Sbjct: 196 MPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPR-ASLSMMP------STALLI 248

Query: 387 NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
             P RA+ +G++S   +  +DS A  T     P++ +        P       SL   PS
Sbjct: 249 RTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTAS--------PTGTPSRASLSMTPS 300

Query: 447 SGVMSTEQMSATASRVMS-AQLT-MAKTSGAMPTGSMKAVAKQYKRATASGKMS------ 498
           +  +      A+ + ++S   LT M  T+    T    ++ +   RA+ +GK S      
Sbjct: 301 TASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTG 360

Query: 499 TPLRRAPTSGAMSTQPVT---ATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMR 555
           TP R +PT G+ ST  +T   +TAS T + P+ +   + S + L  + P          R
Sbjct: 361 TPSRASPT-GSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP----------R 409

Query: 556 TMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALS 615
              +G+ S   +  M S A  +P  T   +  T T   R + +G  S    R+  +G  S
Sbjct: 410 ASPTGMLSRTSITKMDSTA--SPTRTPPRASPTGT-PPRASPTGTPS----RASPTGTQS 462

Query: 616 KPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTA 675
               T   S    T   +T +    P+           S+ +M  TAS  ++ +  R + 
Sbjct: 463 TASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTAS--ITRTPSRASP 520

Query: 676 SGAMSTSQMTATVSGGMSM--PLMRAQDPGVMPASLMR--AKVSGKMLSQPMSTQDPGGM 731
           +   ST+  T + S  ++M  P   A       ASL R  ++ S    S+   T+ P  +
Sbjct: 521 TWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTV 580

Query: 732 SMSPM-KSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSS 790
            ++ M  S +  GM   +  + + S+  +    S    T     + P E P    RAS +
Sbjct: 581 LLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETP---PRASPT 637

Query: 791 G--EMSLPLMRAPASGEIATPLRSPAYGAMSAPQMT 824
           G    + P    P +    TP R+   G  S    T
Sbjct: 638 GTPPRASPTGTPPRASPTGTPPRASPTGTPSRASPT 673


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 205/940 (21%), Positives = 347/940 (36%), Gaps = 145/940 (15%)

Query: 308  SSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTM-PA 366
            S++L +SP S  ++   L VP       L  PAP     +P  +T  P   + ++T+  +
Sbjct: 41   SAVLSNSPHSRDLAGWPLGVPQ------LASPAPGHRENAPMTLTTSPHDTLISETLLNS 94

Query: 367  PGSGAMSPWSTQNVDSEMMSNPP-----------VRATASGVMSAPPVR--------ALD 407
            P S   S   T     ++ + PP           V  T+  +  + P          A  
Sbjct: 95   PVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIITISHPTSICVTTTQVAFT 154

Query: 408  SGAMSTPLMGAPASGNMSTLQKTVPASG--AMTTS----------LMTVPSSGVMSTEQM 455
            S   STP+   P +   ST   T    G  AMT+S          ++TV  S V +T+  
Sbjct: 155  SSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATDTT 214

Query: 456  SATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPV 515
              T   + S   T  +T   +PTGS+          T+   + T L+ A TS    T P+
Sbjct: 215  FHTT--ISSTTRTTERTP--LPTGSIHTT-------TSPTPVFTTLKTAVTS----TSPI 259

Query: 516  TATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQM---RTMASGLTSAAQMKAMTS 572
            T++ + T ++  +T  AS   +   + +P    +S   +    T+ SG+T+   +  + +
Sbjct: 260  TSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTTPLSTLVT 319

Query: 573  GAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKM 632
               +T   +  TS +T       T +   +     +  +G LS     P  S ++ T   
Sbjct: 320  TLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPT--- 376

Query: 633  TTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGM 692
            T TA+  M  L+   T   + S P  + +       S      S    TS +T T +   
Sbjct: 377  TETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTS-----HSTPRFTSSITTTETPSH 431

Query: 693  SMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSD 752
            S P   +        S  R+     +++   +T        S + +         S TS 
Sbjct: 432  STPRFTSSFTNTKTTS-HRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSS 490

Query: 753  VMSTPT----VRAWTSETMSTPLMRTSDPGERPSLLTR----------ASSSGEMSLPLM 798
            + +T T     R++TS   +T     S      S+ T           +SS      PL 
Sbjct: 491  ITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLH 550

Query: 799  RAPASGEIATPLRSPAY---GAMSAPQMTATAS----GMMSSMPQVKAPISGAMSMPLTR 851
              P      T  ++ ++   G  S+   T T S    G  SS+   +       S  L+ 
Sbjct: 551  STPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPS--LSS 608

Query: 852  STASGGMSMPLMRAPDSRVTSTSQMMPT------ASGDMCTLPVR--APASGGVSSPLVR 903
            ST    +S           TS + + PT       S D+ T  +R   P+S G S+ L  
Sbjct: 609  STIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTT 668

Query: 904  APASGTMSTPL-----------RRPSACETVSTELMRASASGHMSTAQTTAMVS-----G 947
                 ++ T +             PS   T ++ L+  + S  MST + T  ++      
Sbjct: 669  TTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLV-GTTSPTMSTVRMTLRITENTPIS 727

Query: 948  GMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATS-------TLQTSVANSRS 1000
              S  ++  P + T   P++++ A+G  + P   T+  G+T        TL  S A S  
Sbjct: 728  SFSTSIVVIPETPTQTPPVLTS-ATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTI 786

Query: 1001 MSLSQTTY--TVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSM 1058
            +S SQ     T S  + T P         ST  ++ S++ +        T         +
Sbjct: 787  VSTSQVPIPSTHSSTLQTTP---------STPSLQTSLTSTSEFTTESFTRGSTSTNAIL 837

Query: 1059 PQMTATDSRGMSTPLMRASGPGTMSTP---QTAFGVMSTPEIKATDS-GEA--------- 1105
               +        T +M +S      TP    T   V S+P I +T++ G A         
Sbjct: 838  TSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLS 897

Query: 1106 STSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLT 1145
            S++  + +++ S  T+ +T  TP +    P   P  G +T
Sbjct: 898  SSATTSTSSTSSSLTTALTEITPFSYISLPSTTPCPGTIT 937



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 226/1110 (20%), Positives = 407/1110 (36%), Gaps = 152/1110 (13%)

Query: 61   TSTQLMTSPVFDTMSAPLMGVPNSGALS------PPLM-PASDSGALSPLLMPASDSGAL 113
            TS   +  P  +  SA L   P+S  L+      P L  PA      +P+ +  S    L
Sbjct: 27   TSISQVPFPRAEAASAVLSNSPHSRDLAGWPLGVPQLASPAPGHRENAPMTLTTSPHDTL 86

Query: 114  --SPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPA 171
                LL   + S T +   S   + V +    T P     SAT      ++ I  ++ P 
Sbjct: 87   ISETLLNSPVSSNTSTTPTSKFAFKVET----TPPTVLVYSATTECVYPTSFIITISHPT 142

Query: 172  PSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSP 231
             S  V  T +  TSS    STP+   P +   S   M     G  +    P+ ++   +P
Sbjct: 143  -SICVTTTQVAFTSSYT--STPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETP 199

Query: 232  LQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNS 291
            +              +T   S       +S TD+    + I S   +   +P PT + ++
Sbjct: 200  I--------------VTVTPSS------VSATDT-TFHTTISSTTRTTERTPLPTGSIHT 238

Query: 292  GGIPTPLMSDLDSGIMSS--LLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA 349
               PTP+ + L + + S+  +  S   +  +++   +       +TL  P     + +P 
Sbjct: 239  TTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPV 298

Query: 350  LMT-ALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDS 408
            L T  + SG+  T T P        P +         +  P   T++   S   +    S
Sbjct: 299  LSTETITSGI--TNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTS 356

Query: 409  --GAMSTPLMGAPASGNMSTLQ-KTVPASGAMTTSL-MTVPSSGVMSTEQMSATASRVMS 464
              G +ST     P S ++ T +  T P +  +TT+  ++  S+   S+  + +T +   +
Sbjct: 357  MTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHST 416

Query: 465  AQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMS 524
             + T + T+   P+ S       +          T   R+P+  ++ T   T + S    
Sbjct: 417  PRFTSSITTTETPSHSTPRFTSSFTNT------KTTSHRSPSFTSLITTTETTSHSTPSF 470

Query: 525  MPQLTVPASGSMSMLQMRAPVSEA-MSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQ 583
               +T   + S S     + ++    +    R+  S +T+       T+   S+   T  
Sbjct: 471  TSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTET 530

Query: 584  TSGSTSTL--LMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMP 641
            TS ST +    +  T + + S P + S  +   +   +TP  + ++ T   T T S + P
Sbjct: 531  TSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITT---TETTSHSTP 587

Query: 642  TLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMS--TSQMTATVSGGMSMPLMRA 699
                    + +++  + T  ++  LS+S +  T S + +  TS  T + +     P+  +
Sbjct: 588  GF------TSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPS 641

Query: 700  QDPGVMPASLMRAKVS---GKMLSQPMSTQDPG-GMSMSPMKSMTAGGMQMNSPTSDVMS 755
                 +P + +R       G   S   +T  P     +S + + T   +  +SP+     
Sbjct: 642  SLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRT--HIISSSPSIQSTE 699

Query: 756  TPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAY 815
            T ++   TS TMST  M           +T  +     S  ++  P +     P+ + A 
Sbjct: 700  TSSLVGTTSPTMSTVRMTLR--------ITENTPISSFSTSIVVIPETPTQTPPVLTSAT 751

Query: 816  GAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQ 875
            G  ++P  T    G   S        S +    LT STA             S + STSQ
Sbjct: 752  GTQTSPAPTTVTFGSTDS--------STSTLHTLTPSTAL------------STIVSTSQ 791

Query: 876  MMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGH 935
            +               P     SS L   P++ ++ T L   S  E  +    R S S +
Sbjct: 792  V---------------PIPSTHSSTLQTTPSTPSLQTSL--TSTSEFTTESFTRGSTSTN 834

Query: 936  MSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSV 995
                  + ++       +M +  S     P+ S       S P + +  +  ++    S+
Sbjct: 835  AILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSA----SI 890

Query: 996  ANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMP-------LPRAT 1048
                S+S S TT T S   +      + +    T F   S+  + P P       +P + 
Sbjct: 891  TGFPSLSSSATTSTSSTSSS-----LTTALTEITPFSYISLPSTTPCPGTITITIVPASP 945

Query: 1049 ASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST-----------PEI 1097
               C   + M   T   S   +TPL        M T  T+  + +T           PE 
Sbjct: 946  TDPC---VEMDPSTEATS-PPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPES 1001

Query: 1098 KATDSGEASTSHINITASGSKPTSHMTATT 1127
            +++ S  AS+S    T +G+ PT+ +  +T
Sbjct: 1002 ESSISPNASSS----TGTGTVPTNTVFTST 1027



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 102/525 (19%), Positives = 201/525 (38%), Gaps = 63/525 (12%)

Query: 32   MTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGAL--SP 89
            +T T      L + +    + T      GTST L T+  F ++   +  +P    +  S 
Sbjct: 633  VTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSS 692

Query: 90   PLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFG 149
            P + ++++ +L                       GT SP +ST    +       I  F 
Sbjct: 693  PSIQSTETSSLV----------------------GTTSPTMSTVRMTLRITENTPISSFS 730

Query: 150  TMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMST---SSSEAMSTPLMLAPDSGELSPI 206
            T   +++V P++   +P  + + ++G   +P  +T    S+++ ++ L     S  LS I
Sbjct: 731  T---SIVVIPETPTQTPPVLTS-ATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTI 786

Query: 207  LMQDMNP-------GVMSTQPVPAPSSEAMSPLQITDED-------TEAMSKVLMTALAS 252
            +     P        + +T   P+  +   S  + T E        T A+     T + S
Sbjct: 787  VSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWS 846

Query: 253  GEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSG-----GIPTPLMSDLDSGIM 307
               + ++ S   S +I+ +  + + S  +SP   ST+N G     G P+   S   S   
Sbjct: 847  STPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSS 906

Query: 308  SSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAP 367
            +S  +++  +E+     +S+P     ST P P      + PA  T     + P+    +P
Sbjct: 907  TSSSLTTALTEITPFSYISLP-----STTPCPGTITITIVPASPTDPCVEMDPSTEATSP 961

Query: 368  GSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTL 427
             +   +P +     +EM++ P    T+  + +        S  M         + + ST 
Sbjct: 962  PT---TPLTVFPFTTEMVTCP----TSISIQTTLTTYMDTSSMMPESESSISPNASSSTG 1014

Query: 428  QKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQ 487
              TVP +   T++ +    + + ++  +      V +  LTM K S ++PT    +    
Sbjct: 1015 TGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVSTIPLTM-KPSSSLPTILRTSSKST 1073

Query: 488  YKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPA 532
            +     +    TP+    T   ++++  T   S+  +   LT  A
Sbjct: 1074 HPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTA 1118


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 250/1168 (21%), Positives = 422/1168 (36%), Gaps = 212/1168 (18%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGAL---------SP 102
            + S + P  TST   T+    T+  P      SG  + P +P S +  L          P
Sbjct: 1309 TASTASPATTSTAQSTTRTTMTLPTPA----TSG--TSPTLPKSTNQELPGTTATQTTGP 1362

Query: 103  LLMPASDSGALSPLL-MPALDSGT-LSPLLSTSEYGVMSPGMMT---------IPDFGTM 151
               PAS +G  +P    P   + T  +   +T+EY        T         +P  G +
Sbjct: 1363 RPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPV 1422

Query: 152  SATLMVA------PDSAEIS-PLAMP-------APSSGVVCTPI---MSTSSSEAMSTPL 194
            +AT   A      P   E + P  +P        PS+  V TP    M+TS+S   S P 
Sbjct: 1423 TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNH-SAPT 1481

Query: 195  MLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMT---ALA 251
               P    L         P +    P  + +S+A S        T   S    T    + 
Sbjct: 1482 GTIPPPTTLKATGSTHTAPPIT---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVT 1538

Query: 252  SGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQN--SGGIPTPLMSDLDSGIMSS 309
                +++  + T +   + +  +  A+    P P +T +  +G  P      + +    +
Sbjct: 1539 PTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT 1598

Query: 310  LLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGS 369
                   S   +T    VP        P            + T+     MPT T+P P  
Sbjct: 1599 TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPP-- 1656

Query: 370  GAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQK 429
                  +T        + P +  T SG   A  + +L++   ST L    +S + +    
Sbjct: 1657 ------TTLKATGSTHTAPTMTLTTSGTSQA--LSSLNTAKTSTSLHSHTSSTHHAEATS 1708

Query: 430  T-----VPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSA----------QLTMAKTSG 474
            T      P   +  T  MTV +SG   +    +TA    S           ++T   T+ 
Sbjct: 1709 TSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTS 1768

Query: 475  AMP----TGSMKAVAKQYKRATASGKMSTPLR-RAPTSGAM---STQPVTATASETM--- 523
              P    TG+   VA  +  +  S ++ TP    +P +G     ST PVTAT+ +T    
Sbjct: 1769 ITPNHTSTGTRTPVA--HTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTY 1826

Query: 524  ---SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLM 580
               S P  T+P         +  P +  + +P    MA+    +A + +M +G +  P  
Sbjct: 1827 PTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT----SASIHSMPTGTIPPPT- 1881

Query: 581  TAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAM 640
            T + +GST T                          P MTP  SGT  +    +TA  + 
Sbjct: 1882 TIKATGSTHTA-------------------------PPMTPTTSGTSQSPSSFSTAKTS- 1915

Query: 641  PTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQ 700
             T L   T S     P++T T++  ++    + T++G  +    T + S           
Sbjct: 1916 -TSLPYHTSS--THHPEVTPTSTTNITP---KHTSTGTRTPVAHTTSASSSR-------- 1961

Query: 701  DPGVMPASLMRAKVSGKMLSQPMSTQDP--GGMSMSPMKSMTAGGMQMNS----PTSDVM 754
                              L  P +T  P  G    S    MTA   Q  +    P+    
Sbjct: 1962 ------------------LPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT 2003

Query: 755  STPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPA 814
            + PT     S ++ TP   T        + T AS         + +  +G +  P    A
Sbjct: 2004 TLPTHVPPFSTSLVTPSTHTVIITTHTQMATSAS---------IHSTPTGTVPPPTTLKA 2054

Query: 815  YGAM-SAPQMTATASGM------MSSMPQVKAPISGAMSMPLTRSTASGGM----SMPLM 863
             G+  +AP MT T SG        S+     + IS +  +P   S+          +P +
Sbjct: 2055 TGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHL 2114

Query: 864  RAPDSRVTSTSQMMPTASGDMC---TLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSAC 920
             +  + V++T+Q+  + S       T+    P+S   SSP   +P+ GT S+ +  P   
Sbjct: 2115 SSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSH--SSPQTSSPSVGTSSSFVSAPVHS 2172

Query: 921  ETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLM 980
             T+S+      +   +ST  TTA VS     P   +PA+ T     +    S   ++  +
Sbjct: 2173 TTLSS-----GSHSSLSTHPTTASVSASPLFP--SSPAASTTIRATLPHTISSPFTLSAL 2225

Query: 981  ETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSF--------- 1031
              +++   S   +S   S +++   T  T +         + ++ +RSTS          
Sbjct: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF 2285

Query: 1032 --MRASVSGSMPMPLPRATASGCGMGMSMPQ--MTATDSRGMSTPLMRASGP-GTMSTP- 1085
              + + V+G    P+   T    G  +S     +T++ +   STP   AS P  ++ TP 
Sbjct: 2286 VSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTP---ASAPVSSLGTPT 2342

Query: 1086 QTAFGVMSTPEIKATDSGEASTSHINIT 1113
             T+ GV S  E +   + +   +++ +T
Sbjct: 2343 PTSPGVCSVREQQEEITFKGCMANVTVT 2370



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 221/1056 (20%), Positives = 381/1056 (36%), Gaps = 149/1056 (14%)

Query: 177  VCTPIMSTSSSEAMSTPLM---------LAPDSGELSPI-LMQDMNPGVMSTQPVPAPSS 226
            VC P M  ++ +  +TP +         + P +G  + I L+    P   S     +P+ 
Sbjct: 1192 VCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251

Query: 227  EAMSPLQITDEDTEAMS-------KVLMTALASG-----EISSLLMSGTDSEAISSLIMS 274
              + P  +T     A S         +     SG      + S     T ++A +    S
Sbjct: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311

Query: 275  AVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPG-SEVMSTPLLSVPDAGEM 333
              +   TS   ++T+ +  +PTP  S     +  S     PG +   +T     P +   
Sbjct: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371

Query: 334  STLPKPA-PDAEAMSPALMTALPSGVM-----------PTQTMPAPGSGAMSPWS----- 376
             T P+P  P     +    T   +              PT   P P +G ++  S     
Sbjct: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATT 1431

Query: 377  ----TQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVP 432
                  + ++ + ++ P  +T+    S   V       M+T      A         T+ 
Sbjct: 1432 TYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLK 1491

Query: 433  ASGAMTTSLMTVPSSGVMSTEQMSATASRVMSA-------------QLTMAKTSGAMPTG 479
            A+G+  T+    P++   S    S + ++  ++               T   T    PT 
Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 480  SMKAVAKQYKRATASGKMSTPL-RRAPTSGA---MSTQPVTATASETM------SMPQLT 529
            +       +  +  S +   P    +P +G+    ST P+TAT+ +T       S PQ T
Sbjct: 1552 TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 530  VPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTS 589
            +P         +  P +  +  P    MA    ++A + +M +G +  P  T + +GST 
Sbjct: 1612 LPTHVPPFSTSLVTPSTHTVITPTHAQMA----TSASIHSMPTGTIPPP-TTLKATGSTH 1666

Query: 590  TL-LMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDT 648
            T   M  T SG           S ALS  L T K S ++ +   +T  +EA  T     T
Sbjct: 1667 TAPTMTLTTSG----------TSQALSS-LNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715

Query: 649  VS-GALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPA 707
             +  +   P MT T SG    S  R + S A +++ + +  S      +       + P 
Sbjct: 1716 PNPTSTGTPPMTVTTSG---TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPN 1772

Query: 708  SLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSP---TSDVMSTPTVRAWTS 764
                             T+ P   + S   S        +SP   T+ + ST  V A + 
Sbjct: 1773 ------------HTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF 1820

Query: 765  ETMST----PLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIAT--PLRSPAYGAM 818
            +T +T        T+ P   PS  T   +    ++ +   P   ++AT   + S   G +
Sbjct: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVII---PTHTQMATSASIHSMPTGTI 1877

Query: 819  SAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA----PDSRVTSTS 874
              P  T  A+G   + P +    SG    P + STA    S+P   +    P+   TST+
Sbjct: 1878 -PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936

Query: 875  QMMP--TASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACET----VSTELM 928
             + P  T++G       R P +   S+   R P   T  +P    S   +     +T   
Sbjct: 1937 NITPKHTSTG------TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQ 1990

Query: 929  RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGAT 988
              +     S  QTT           +  P++ T+ +   + MA+       + +  +G  
Sbjct: 1991 TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSAS----IHSTPTGTV 2046

Query: 989  STLQTSVANSRSMSLSQTTYTVSGRMAT----APIRASASGARSTSFMRASVSGSMPMPL 1044
                T  A   + +    T T SG   T    +   AS+S   S+S++  + S S P   
Sbjct: 2047 PPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQN-SSSRPPSS 2105

Query: 1045 PRAT-----ASGCGMGMSMPQMTATDSRGMSTPLMRAS-GPGTMSTPQTAFGVMSTPEIK 1098
            P  T     +S      +  Q++++ S   S P   +S  P + S+PQT     S+P + 
Sbjct: 2106 PITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQT-----SSPSVG 2160

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPP 1134
             + S  ++  H    +SGS  +     TT   +  P
Sbjct: 2161 TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP 2196



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 210/912 (23%), Positives = 322/912 (35%), Gaps = 119/912 (13%)

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSV- 327
            +S  +  ++S G SP    T  S    TPL   L + + SS   +S G     T  ++  
Sbjct: 1226 TSTTIGLLSSTGPSPSSNHTPASP-TQTPL---LPATLTSSKPTASSGEPPRPTTAVTPQ 1281

Query: 328  ------PDAGEMSTLPKPA-------PDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSP 374
                  P A   ST  KP          A   SPA  +   S    T T+P P +   SP
Sbjct: 1282 ATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSP 1341

Query: 375  WSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP-------ASGNMSTL 427
               ++ + E+        TA+      P  A  +G  +TP  G P        +   +T 
Sbjct: 1342 TLPKSTNQELPG-----TTATQTTGPRPTPASTTGP-TTPQPGQPTRPTATETTQTRTTT 1395

Query: 428  QKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQ 487
            + T P +   T S  T   S V ST  ++AT+    +   T +     +PT         
Sbjct: 1396 EYTTPQTPHTTHSPPTA-GSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPF---- 1450

Query: 488  YKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSE 547
               +T+    ST     PT   M+T     +A      P  T+ A+GS        P + 
Sbjct: 1451 ---STSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTS 1507

Query: 548  AMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMR 607
              S  Q  +  S   +   + + TS      +    T  ST+T+    T++   +     
Sbjct: 1508 GTS--QAHSSFSTNKTPTSLHSHTSSTHHPEV----TPTSTTTITPNPTSTRTRTPVAHT 1561

Query: 608  SLASGALSKPLMT---PKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT-DTAS 663
            + A+ +   P  T   P    + F+     TA+    T     T     S PQ T  T  
Sbjct: 1562 NSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTT-----TTYPTPSHPQTTLPTHV 1616

Query: 664  GGLSASLMRDTASGAMS-TSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQP 722
               S SL+  +    ++ T    AT +   SMP      P  +       K +G   + P
Sbjct: 1617 PPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTL-------KATGSTHTAP 1669

Query: 723  MSTQDPGGMSMSPMKSMTA-GGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERP 781
              T    G S +     TA     ++S TS           TS T  TP    +  G  P
Sbjct: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS--TSTTNITP--NPTSTGTPP 1725

Query: 782  SLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTA-----TASGMMSSMPQ 836
              +T + +S   S     A  S  + +   S  +  +++   T+     T++G  + +  
Sbjct: 1726 MTVTTSGTSQSRS-SFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784

Query: 837  VKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTS--TSQMMPTASGDMCTLPVRAPAS 894
              +  S  +  P T  +   G + P+        TS  T+   PT S    TLP   P+ 
Sbjct: 1785 TTSATSSRLPTPFTTHSPPTG-TTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPS- 1842

Query: 895  GGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLM 954
               S+ LV  P++ T+  P              M  SAS H       +M +G +  P  
Sbjct: 1843 --FSTSLV-TPSTHTVIIPTHTQ----------MATSASIH-------SMPTGTIPPPTT 1882

Query: 955  RAPASGTMPMPLMSAMASGEMSMPLMETMASGATS-TLQTSVANSRSMSLSQTTYTVSGR 1013
                  T   P M+   SG    P   + A  +TS    TS  +   ++ + TT      
Sbjct: 1883 IKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITP-- 1940

Query: 1014 MATAPIRASASGARSTSFMRASVSGSMPMPLPRATAS---GCGMGMSMPQMTATDSRGMS 1070
                  + +++G R+      S S S  +P P  T S   G     S   MTAT  +  +
Sbjct: 1941 ------KHTSTGTRTPVAHTTSASSSR-LPTPFTTHSPPTGSSPFSSTGPMTATSFQTTT 1993

Query: 1071 TPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPET 1130
            T         T S PQT       P   +T     ST  + IT      TS    +TP  
Sbjct: 1994 T-------YPTPSHPQTTLPTHVPP--FSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044

Query: 1131 AKPPPKEVPSFG 1142
              PPP  + + G
Sbjct: 2045 TVPPPTTLKATG 2056



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 104/458 (22%), Positives = 173/458 (37%), Gaps = 90/458 (19%)

Query: 691  GMSMPLMRAQDPGVMPASLMRAKVSGKMLSQ--PMSTQDPGGMSMSPMKSMTAGGMQMNS 748
            G+ +P M    P   P +  +   +G   +Q  PM+    G  +   + S T      N 
Sbjct: 1191 GVCVPCMPPTTP--QPPTTPQLPTTGSRPTQVWPMT----GTSTTIGLLSSTGPSPSSNH 1244

Query: 749  PTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIAT 808
              +    TP + A  + T S P   + +P    + +T  ++SG      +R+ A+    T
Sbjct: 1245 TPASPTQTPLLPA--TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVT 1302

Query: 809  PLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDS 868
               + A  + ++P  T+TA     +           M++P T +T+    ++P       
Sbjct: 1303 QATTRATASTASPATTSTAQSTTRT----------TMTLP-TPATSGTSPTLP------- 1344

Query: 869  RVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELM 928
               ST+Q +P  +    T P   PAS   + P    P   T      RP+A ET  T   
Sbjct: 1345 --KSTNQELPGTTATQTTGPRPTPAS--TTGPTTPQPGQPT------RPTATETTQTR-- 1392

Query: 929  RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGAT 988
                +   +T QT        S P   +P   T P+   S  A+     P      S   
Sbjct: 1393 ---TTTEYTTPQTPHTTH---SPPTAGSPVPSTGPVTATSFHATTTYPTP------SHPE 1440

Query: 989  STLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRAT 1048
            +TL T V    +  ++ +T+TV       P  A  + + S     ++ +G++P   P  T
Sbjct: 1441 TTLPTHVPPFSTSLVTPSTHTV-----ITPTHAQMATSASN---HSAPTGTIP---PPTT 1489

Query: 1049 ASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTS 1108
                G   + P +T T S             GT S   ++F    TP   +  S  +ST 
Sbjct: 1490 LKATGSTHTAPPITPTTS-------------GT-SQAHSSFSTNKTP--TSLHSHTSSTH 1533

Query: 1109 HINITASGS-----KPTSHMTAT------TPETAKPPP 1135
            H  +T + +      PTS  T T      +  +++PPP
Sbjct: 1534 HPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP 1571



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 131/615 (21%), Positives = 213/615 (34%), Gaps = 79/615 (12%)

Query: 567  MKAMTSGAMSTPLMTAQTSGSTSTLLMRDTAS--GVMSCPQMRSLASGALSKPLMTPKAS 624
            M   T    +TP +    S  T    M  T++  G++S       ++   + P  TP   
Sbjct: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256

Query: 625  GTMFTEKMTTTASEAM--PTLLMRDTVSGALSMPQMTDTASGG-LSASLMRDTASGAMST 681
             T+ + K T ++ E     T +     SG      +  TA+   ++ +  R TAS A   
Sbjct: 1257 ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPA 1316

Query: 682  SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTA 741
            +  TA  +   +M L      G  P      K + + L    +TQ  G     P  + T 
Sbjct: 1317 TTSTAQSTTRTTMTLPTPATSGTSPTL---PKSTNQELPGTTATQTTGPR---PTPASTT 1370

Query: 742  GGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAP 801
            G      PT+     PT R   +ET  T   RT+     P       S      P+   P
Sbjct: 1371 G------PTTPQPGQPT-RPTATETTQT---RTTTEYTTPQTPHTTHSPPTAGSPV---P 1417

Query: 802  ASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMP 861
            ++G +          +  A     T S   +++P    P S ++  P T +  +   +  
Sbjct: 1418 STGPVTAT-------SFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470

Query: 862  LMRAPDSRVTSTSQMMPT---ASGDMCTLPVRAPASGGVSSP-----LVRAPAS-GTMST 912
               A +    + +   PT   A+G   T P   P + G S         + P S  + ++
Sbjct: 1471 ATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTS 1530

Query: 913  PLRRPSACETVSTELMRASASGHMST--AQTTAMVSGGMSKPLM-RAPASGTMPMPLMSA 969
                P    T +T +     S    T  A T +  S     P    +P +G+ P      
Sbjct: 1531 STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGP 1590

Query: 970  MASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARST 1029
            M +            S   +TL T V    +  ++ +T+TV       P  A  + + S 
Sbjct: 1591 MTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV-----ITPTHAQMATSASI 1645

Query: 1030 SFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAF 1089
              M    +G++P P    T    G   + P MT T S G S  L       +++T +T+ 
Sbjct: 1646 HSMP---TGTIPPP---TTLKATGSTHTAPTMTLTTS-GTSQAL------SSLNTAKTST 1692

Query: 1090 GVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTPALC 1149
             +          S  +ST H   T+         T+TT  T  P     P   + T    
Sbjct: 1693 SL---------HSHTSSTHHAEATS---------TSTTNITPNPTSTGTPPMTVTTSGTS 1734

Query: 1150 YLLEEQEAARGSCSV 1164
                    A+ S S+
Sbjct: 1735 QSRSSFSTAKTSTSL 1749


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 216/1124 (19%), Positives = 375/1124 (33%), Gaps = 135/1124 (12%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3315

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 3316 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 3487

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 3488 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 3535

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 3590

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 3591 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 3639

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 3640 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 3749

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 3750 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 3806

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 3857

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 3858 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 3910

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 3911 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 3962

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 3963 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 4016

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 4077 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 4123

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 4124 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +G       P  T+T        L  ++ P   STPQT+    S+P  +
Sbjct: 4184 VTPTPTPTGTQTG------PPTHTST---APIAELTTSNPPPESSTPQTSRST-SSPLTE 4233

Query: 1099 ATDSGEASTSHINITASG--SKPTSHMTATTPETAKPPPKEVPS 1140
            +T         I +T++   S PT+  T +   T  PPP    S
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 4277



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 216/1169 (18%), Positives = 375/1169 (32%), Gaps = 131/1169 (11%)

Query: 23   NKQMAFC--RPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMT---SPVFDTMSAP 77
            N Q   C  +P T T    +        PI +T+   P  T T   T   +P+  T +  
Sbjct: 1872 NVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1931

Query: 78   LMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGV 137
                P +G  +P   P + +  ++P   P   +G  +P   P   + T++P  + +  G 
Sbjct: 1932 PTPTP-TGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTTTTVTP--TPTPTGT 1985

Query: 138  MSPGMMTIPDF----------GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSS 187
             +P    I             GT + T      +  ++P   P  +     TPI +T++ 
Sbjct: 1986 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2045

Query: 188  EAMSTPL-MLAPDSGELSPILMQDMNPGVMSTQP---VPAPSSEAMSPLQI-TDEDTEAM 242
                TP     P +  ++        P    TQ     P  ++  ++P    T   T   
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105

Query: 243  SKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDL 302
            + +  T   +   +    +GT +   + +  +   +   +P PT TQ      TP  + +
Sbjct: 2106 TPITTTTTVTPTPTP---TGTQTPTTTPITTTTTVT--PTPTPTGTQ------TPTTTPI 2154

Query: 303  DSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQ 362
             +    +   +  G++  +T     P     +  P P P              + V PT 
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 2209

Query: 363  TMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASG 422
              P P +G  +P +T    +  ++  P   T +G  + P    + +    TP    P   
Sbjct: 2210 --PTP-TGTQTPTTTPITTTTTVTPTP---TPTGTQT-PTTTPITTTTTVTP---TPTPT 2259

Query: 423  NMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMK 482
               T     P +  +TT+    P+     T+  + T         T   T    PTG+  
Sbjct: 2260 GTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQT 2309

Query: 483  AVAKQYKRATASGKMSTPL--RRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQ 540
                     T      TP   +   T+   +T  VT T + T +    T P + + ++  
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 541  MRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGV 600
               P        Q  T     T+       T     TP  T  T+  T+T+    T +G 
Sbjct: 2370 TPTPTGT-----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGT 2422

Query: 601  MSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEA---MPTLLMRDTVSGALSMPQ 657
             + P    + +     P  TP  + T  T  +TTT +      PT     T +   +   
Sbjct: 2423 QT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481

Query: 658  MTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGK 717
            +T T +          T +   +T+ +T T +   +      Q P   P +         
Sbjct: 2482 VTPTPT---------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-- 2530

Query: 718  MLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMR---- 773
                P  TQ P    ++   ++T       +PT     TPT    T+ T  TP       
Sbjct: 2531 -TPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 774  ---TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGM 830
               T+ P    + +T   +      P      +    TP  +P  G  +      T +  
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTT 2642

Query: 831  MSSMP-----QVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMC 885
            ++  P     Q         +  +T +    G   P      +  T T    PT +    
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 886  TLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMST 938
            T P+         P   G  +P      + T  TP   P+  +T +T  +  +      T
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT------T 2756

Query: 939  AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANS 998
              T      G   P        T P+   + +              +  T+T   +   +
Sbjct: 2757 TVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 999  RSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSM 1058
             + + + TT  ++      P          T+    + +   P P P  T +      + 
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT----TT 2865

Query: 1059 PQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSK 1118
            P  T T      TP    +   T  T  T      TP    T +    T+   +T + + 
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925

Query: 1119 PTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
              +    TTP T        P+  G  TP
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 222/1128 (19%), Positives = 370/1128 (32%), Gaps = 140/1128 (12%)

Query: 52   STSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSG 111
            +T+ S P  T+T   T P   T S P+         + P  P S +    P   P+    
Sbjct: 1419 TTTPSPPTTTTT---TPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSP--- 1472

Query: 112  ALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPA 171
               P   P+  + T SP  +T+     +P   T P   T +     A  +  + P   P+
Sbjct: 1473 ---PTTTPSPPTTTPSPPTTTTT----TPPPTTTPSPPTTTPITPPA-STTTLPPTTTPS 1524

Query: 172  PSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPA----PSSE 227
            P +    TP  +T+ S   +TP+     +  L P       P   +T P       P++ 
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584

Query: 228  AMSPLQIT----------DEDTEAMSKVLMTALASGEISSLLMSGTDSEAIS-SLIMSAV 276
              SP  IT             T   +    T   S   ++ +   T +  +  +   S  
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644

Query: 277  ASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTL 336
             +  T+P PT+T +     TP  S   +   +    ++P S + +TP      +   +T+
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTP--SPPITTTTTPPPTTTPSSPITTTP------SPPTTTM 1696

Query: 337  PKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAM---SPWSTQNVDSEMMSNPPVRAT 393
              P+P     SP   T  PS    + T P+P    M   SP +T +  +  M+  P   T
Sbjct: 1697 TTPSPTTTPSSPITTTTTPS----STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT 1752

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPA------SGAMTTSLMTVPSS 447
            +S + + P            P +  P     ST   T P       +G + +        
Sbjct: 1753 SSPLTTTP----------LPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKP 1802

Query: 448  GVMSTEQMSATASRVMSAQLTMAKTS-GAMPTGSM--KAVAKQYKRATASGKMSTPLRRA 504
            G   TE +        +A ++   T    +P G +    V           +   P    
Sbjct: 1803 G-GDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVI 1861

Query: 505  PTSGAMS-----------TQPVTATASETMS-MPQLTVPASGSMSMLQMRAPVSEAMSMP 552
            P +  ++           TQP T T + T +  P  T P + + ++     P        
Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTG-----T 1916

Query: 553  QMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASG 612
            Q  T     T+       T     TP  T  T  +T+T+    T +G  + P    + + 
Sbjct: 1917 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPTPTPTGTQT-PTTTPITTT 1973

Query: 613  ALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMR 672
                P  TP  + T  T  +TTT      T+    T +G    P  T   +         
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGT-QTPTTTPITTTTTVTPTPT 2027

Query: 673  DTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMS 732
             T +   +T+ +T T +   +      Q P   P   +    +      P  TQ P    
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP 2084

Query: 733  MSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGE 792
            ++   ++T       +PT     TPT    T+ T  TP   T  P    +  T   ++  
Sbjct: 2085 ITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTT 2135

Query: 793  MSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRS 852
               P    P      TP  +P     +   +T T +   +  P    PI+   +  +T +
Sbjct: 2136 TVTP---TPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTP-TTTPIT--TTTTVTPT 2186

Query: 853  TASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVR-------APASGGVSSPLVRAP 905
                G   P      +  T T    PT +    T P+         P   G  +P     
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2246

Query: 906  ASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMP 965
             + T  TP   P+  +T +T  +        +T  T      G   P        T P+ 
Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITT------TTTVTPTPTPTGTQTPT-------TTPIT 2293

Query: 966  LMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASG 1025
              + +              +  T+T   +   + + + + TT  ++      P       
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353

Query: 1026 ARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTP 1085
               T+    + +   P P P  T +        P  T   +    TP    +G  T +T 
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTT 2405

Query: 1086 QTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
                    TP    T +   +T+ I  T + + PT   T T   T  P
Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTP 2452



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2027

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2028 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2199

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2200 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2247

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2302

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2303 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2351

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2352 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2461

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2462 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2518

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2569

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2622

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2623 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2674

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2675 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2728

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2789 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2835

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 2896 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2050

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2051 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2105

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2222

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2223 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2270

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2325

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2326 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2374

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2375 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2430 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2484

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2485 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2541

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2542 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2592

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2645

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2646 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2697

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2698 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2751

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2811

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2812 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2858

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2859 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 2919 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2974

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2073

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2074 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2128

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2245

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2246 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2293

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2348

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2349 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2397

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2398 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2507

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2508 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2564

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2615

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2668

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2669 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2720

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2721 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2774

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2834

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2835 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2881

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2882 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2941

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 2942 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3046



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2096

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2097 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2151

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2268

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2269 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2316

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2371

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2372 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2420

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2421 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2530

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2531 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2587

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2638

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2691

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2692 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2743

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2744 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2797

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2857

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2858 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2904

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 2965 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2119

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2120 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2291

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2292 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2339

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2394

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2395 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2443

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2444 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2553

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2554 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2661

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2714

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2715 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2766

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2767 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2820

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2880

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2881 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2927

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2987

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 2988 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2142

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2143 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2257

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2314

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2315 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2362

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2417

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2418 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2466

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2467 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2576

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2577 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2633

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2684

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2737

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2738 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2789

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2790 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2843

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2903

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2904 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2950

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2951 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3011 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3115



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2165

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2166 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2337

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2338 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2385

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2440

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2441 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2489

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2490 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2599

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2600 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2656

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2657 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2707

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2760

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2761 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2812

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2813 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2866

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2927 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2973

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3034 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2188

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2189 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2360

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2361 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2408

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2463

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2464 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2512

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2513 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2622

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2623 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2679

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2730

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2783

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2784 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2835

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2836 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2889

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2949

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2950 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 2996

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 2997 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3057 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2153 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2211

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2212 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2383

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2384 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2431

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2486

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2487 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2535

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2536 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2645

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2646 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2753

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2806

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2807 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2858

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2859 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2912

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2972

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2973 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3019

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3079

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3080 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2234

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2235 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2406

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2407 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2454

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2509

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2510 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2558

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2559 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2668

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2669 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2725

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2776

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2829

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2830 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2881

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2882 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2935

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2995

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 2996 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3042

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3103 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2257

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2258 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2429

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2430 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2477

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2532

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2533 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2581

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2582 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2691

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2692 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2748

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2799

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2852

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2853 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2904

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2905 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2958

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3018

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3019 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3065

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3125

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3126 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2280

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2281 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2452

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2453 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2500

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2555

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2556 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2604

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2605 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2714

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2715 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2771

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2822

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2875

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2876 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2927

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2928 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 2981

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3041

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3042 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3088

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3089 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3149 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3253



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2303

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2304 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2475

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2476 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2523

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2578

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2579 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2627

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2628 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2737

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2738 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2794

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2845

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2898

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2899 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2950

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2951 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 3004

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3064

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3065 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3111

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3172 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2326

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2327 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2498

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2499 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2546

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2601

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2602 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2650

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2651 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2760

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2761 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2817

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2868

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2921

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2922 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2973

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2974 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 3027

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3087

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3088 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3134

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3195 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2349

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2350 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2521

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2522 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2569

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2624

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2625 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2673

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2674 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2783

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2784 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2891

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2944

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2945 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2996

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 2997 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 3050

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 3051 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3110

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3111 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3157

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3158 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3217

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3218 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 212/1129 (18%), Positives = 368/1129 (32%), Gaps = 128/1129 (11%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 2372

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 2373 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 2544

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 2545 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 2592

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 2647

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 2648 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 2696

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 2697 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 2806

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 2807 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 2863

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 2914

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +             P  TQ P    ++   ++T     
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---- 2967

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P    
Sbjct: 2968 --TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTG 3019

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
              TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P    
Sbjct: 3020 TQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPTTTP 3073

Query: 866  PDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPS 918
              +  T T    PT +    T P+         P   G  +P      + T  TP   P+
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133

Query: 919  ACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
              +T +T  +  +      T  T      G   P        T P+   + +        
Sbjct: 3134 GTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTG 3180

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
                  +  T+T   +   + + + + TT  ++      P          T+    + + 
Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240

Query: 1039 SMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIK 1098
              P P P  T +      + P  T T      TP    +   T  T  T      TP   
Sbjct: 3241 VTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 1099 ATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 213/1134 (18%), Positives = 367/1134 (32%), Gaps = 147/1134 (12%)

Query: 26   MAFCRPMTETRADVQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSG 85
            MAFC        +VQ      Q   ++T+ ++     T   T+P+  T +      P +G
Sbjct: 1863 MAFC---LNYEINVQCCECVTQPTTMTTTTTE---NPTPPTTTPITTTTTVTPTPTP-TG 1915

Query: 86   ALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTI 145
              +P   P + +  ++P   P   +G  +P   P   + T++P               T 
Sbjct: 1916 TQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTTTTVTP---------------TP 1957

Query: 146  PDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSP 205
               GT + T      +  ++P   P  +     TPI +T++     TP      +G  +P
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP------TGTQTP 2011

Query: 206  ILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDS 265
                   P   +T   P P+         T   T   + +  T   +   +    +GT +
Sbjct: 2012 TT----TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTP---TGTQT 2056

Query: 266  EAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLL 325
               + +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T   
Sbjct: 2057 PTTTPITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT--- 2105

Query: 326  SVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMM 385
              P     +  P P P              + V PT   P P +G  +P +T    +  +
Sbjct: 2106 -TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTV 2160

Query: 386  SNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVP 445
            +  P   T +G  + P    + +    TP    P      T     P +  +TT+    P
Sbjct: 2161 TPTP---TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTP 2208

Query: 446  SSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RR 503
            +     T+  + T         T   T    PTG+           T      TP   + 
Sbjct: 2209 TPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2263

Query: 504  APTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTS 563
              T+   +T  VT T + T +    T P + + ++     P        Q  T     T+
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTT 2318

Query: 564  AAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKA 623
                   T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  
Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTG 2375

Query: 624  SGTMFTEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMS 680
            + T  T  +TTT +      PT     T +   +   +T T +          T +   +
Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPT 2426

Query: 681  TSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMT 740
            T+ +T T +   +      Q P   P +             P  TQ P    ++   ++T
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVT 2483

Query: 741  AGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRA 800
                   +PT     TPT    T+ T  TP   T  P    +  T   ++     P    
Sbjct: 2484 P------TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---T 2531

Query: 801  PASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSM 860
            P      TP  +P     +   +T T +   +  P    PI+   ++  T +    G   
Sbjct: 2532 PTPTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQT 2585

Query: 861  PLMRAPDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTP 913
            P      +  T T    PT +    T P+         P   G  +P      + T  TP
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 914  LRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASG 973
               P+  +T +T  +  +      T  T      G   P        T P+   + +   
Sbjct: 2646 TPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPT 2692

Query: 974  EMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMR 1033
                       +  T+T   +   + + + + TT  ++      P          T+   
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752

Query: 1034 ASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMS 1093
             + +   P P P  T +      + P  T T      TP    +   T  T  T      
Sbjct: 2753 TTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808

Query: 1094 TPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
            TP    T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 216/1132 (19%), Positives = 363/1132 (32%), Gaps = 113/1132 (9%)

Query: 49   PIVSTSASDPGGTSTQ----LMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLL 104
            P  +T+ S P  T+T        SP   T + P      S   + P+ P + +  L P  
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639

Query: 105  MPASDSGALS---PLLMPALDSGTL-SPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPD 160
             P+      +   P   P+  + T  SP ++T+     +P   T P   +   T    P 
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT----TPPPTTTPS--SPITTTPSPPT 1693

Query: 161  SAEISPLAMPAPSSGVVCT--PIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMST 218
            +   +P     PSS +  T  P  +T+ S   +T    +P +    P       P   ++
Sbjct: 1694 TTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753

Query: 219  QPV------PAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLI 272
             P+      P+ +    SP   T   T  +     T        +    G D+E I  + 
Sbjct: 1754 SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVC 1813

Query: 273  MSAVASGGTSPQPTSTQNS--GGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP-- 328
                A+   S + T   +   G +   ++ D+  G++       PG  +     L+    
Sbjct: 1814 GPGWAAN-ISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEIN 1872

Query: 329  -DAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSN 387
                E  T P         +P   T  P     T T     +G  +P +T    +  ++ 
Sbjct: 1873 VQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1932

Query: 388  PPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSS 447
             P   T +G  + P    + +    TP    P      T     P +  +TT+    P+ 
Sbjct: 1933 TP---TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTP 1980

Query: 448  GVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAP 505
                T+  + T         T   T    PTG+           T      TP   +   
Sbjct: 1981 TPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2035

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
            T+   +T  VT T + T +    T P + + ++     P        Q  T     T+  
Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTT 2090

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + 
Sbjct: 2091 VTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQ 2147

Query: 626  TMFTEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTS 682
            T  T  +TTT +      PT     T +   +   +T T +          T +   +T+
Sbjct: 2148 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTT 2198

Query: 683  QMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAG 742
             +T T +   +      Q P   P +             P  TQ P    ++   ++T  
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP- 2254

Query: 743  GMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPA 802
                 +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P 
Sbjct: 2255 -----TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPT 2303

Query: 803  SGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPL 862
                 TP  +P     +   +T T +   +  P    PI+   ++  T +    G   P 
Sbjct: 2304 PTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTTTV--TPTPTPTGTQTPT 2357

Query: 863  MRAPDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLR 915
                 +  T T    PT +    T P+         P   G  +P      + T  TP  
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 916  RPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEM 975
             P+  +T +T  +  +      T  T      G   P        T P+   + +     
Sbjct: 2418 TPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPT 2464

Query: 976  SMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
                     +  T+T   +   + + + + TT  ++      P          T+    +
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
             +   P P P  T +      + P  T T      TP    +   T  T  T      TP
Sbjct: 2525 TTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
                T +    T+   +T + +   +    TTP T        P+  G  TP
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 158/822 (19%), Positives = 280/822 (34%), Gaps = 90/822 (10%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3614

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 3615 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 3786

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 3787 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 3834

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 3889

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 3890 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 3938

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 3939 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P        Q  T     T+     
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTPITTTTTVTP 4048

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
              T     TP  T  T+  T+T+    T +G  + P    + +     P  TP  + T  
Sbjct: 4049 TPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPT 4105

Query: 629  TEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  +TTT +      PT     T +   +   +T T +          T +   +T+ +T
Sbjct: 4106 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQTPTTTPIT 4156

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
             T +   +      Q P   P +     V+         T  P   S +P+  +T     
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP 4215

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPL-----MRTSDPGERPSLLTRASSSGEMSLPLMRA 800
              S T     + +     S T+ + L     M ++ P   P+  T  S    +S P   +
Sbjct: 4216 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP--PS 4273

Query: 801  PASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPIS 842
              +    TP R    G+ SAP  +   +   S+      P+S
Sbjct: 4274 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 217/1149 (18%), Positives = 370/1149 (32%), Gaps = 143/1149 (12%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T +  +T   SP   TM+ P      S  ++    P+S +    P   
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT 1727

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMS-PGMMTIPDFGTMSATLMVAP----- 159
              + S   +P   P     TL P  ++S       P  +T P F   S T    P     
Sbjct: 1728 MTTPSPTTTPS-PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLC 1786

Query: 160  ------DSAEISPLAMPAPSS---GVVCTPIMSTSSSEAMSTPLMLAPDS--GELSPILM 208
                  DS + +    P   +   G VC P  + +    +S    + PD   G+L   ++
Sbjct: 1787 NWTGWLDSGKPN-FHKPGGDTELIGDVCGPGWAAN----ISCRATMYPDVPIGQLGQTVV 1841

Query: 209  QDMNPGVMSTQPVPAPSSE------------------AMSPLQITDEDTEAMSKVLMTAL 250
             D++ G++       P                        P  +T   TE  +    T +
Sbjct: 1842 CDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPI 1901

Query: 251  ASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSL 310
             +    +   + T ++  ++  ++   +   +P PT TQ      TP  + + +    + 
Sbjct: 1902 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ------TPTTTPITTTTTVTP 1955

Query: 311  LMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSG 370
              +  G++  +T     P     +  P P P              + V PT   P P +G
Sbjct: 1956 TPTPTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TG 2007

Query: 371  AMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKT 430
              +P +T    +  ++  P   T +G  + P    + +    TP    P      T    
Sbjct: 2008 TQTPTTTPITTTTTVTPTP---TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT---- 2056

Query: 431  VPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKR 490
             P +  +TT+    P+     T+  + T         T   T    PTG+          
Sbjct: 2057 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITT 2110

Query: 491  ATASGKMSTPL--RRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEA 548
             T      TP   +   T+   +T  VT T + T +    T P + + ++     P    
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT- 2169

Query: 549  MSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRS 608
                Q  T     T+       T     TP  T  T+  T+T+    T +G  + P    
Sbjct: 2170 ----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQT-PTTTP 2222

Query: 609  LASGALSKPLMTPKASGTMFTEKMTTTASEA---MPTLLMRDTVSGALSMPQMTDTASGG 665
            + +     P  TP  + T  T  +TTT +      PT     T +   +   +T T +  
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-- 2280

Query: 666  LSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMST 725
                    T +   +T+ +T T +   +      Q P   P +             P  T
Sbjct: 2281 -------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGT 2330

Query: 726  QDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLT 785
            Q P    ++   ++T       +PT     TPT    T+ T  TP   T  P    +  T
Sbjct: 2331 QTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTT 2381

Query: 786  RASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAM 845
               ++     P    P      TP  +P     +   +T T +   +  P    PI+   
Sbjct: 2382 TPITTTTTVTP---TPTPTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTT-TPITTTT 2434

Query: 846  SMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRA-------PASGGVS 898
            ++  T +    G   P      +  T T    PT +    T P+         P   G  
Sbjct: 2435 TV--TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2492

Query: 899  SPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPA 958
            +P      + T  TP   P+  +T +T  +  +      T  T      G   P      
Sbjct: 2493 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPT----- 2541

Query: 959  SGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAP 1018
              T P+   + +              +  T+T   +   + + + + TT  ++      P
Sbjct: 2542 --TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 1019 IRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASG 1078
                      T+    + +   P P P  T +      + P  T T      TP    + 
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTP 2655

Query: 1079 PGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKPPPKEV 1138
              T  T  T      TP    T +    T+   +T + +   +    TTP T        
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715

Query: 1139 PS-FGMLTP 1146
            P+  G  TP
Sbjct: 2716 PTPTGTQTP 2724



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 187/994 (18%), Positives = 312/994 (31%), Gaps = 96/994 (9%)

Query: 164  ISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQP--- 220
            + P   P+P +    TP  +T+ S  ++T     P +    PI      P   +  P   
Sbjct: 1416 LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTT 1475

Query: 221  VPAPSSEAMSP---LQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVA 277
             P+P +   SP      T   T   S    T +     ++ L   T          S   
Sbjct: 1476 TPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTP--------SPPT 1527

Query: 278  SGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLP 337
            +  T+P PT+T  S    TP+     +  +      SP     +TP  +   +   +T P
Sbjct: 1528 TTTTTPPPTTTP-SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586

Query: 338  KPAPDAEAMSPALMTALP----SGVMPTQTMPAPGSGA--MSPWSTQNVDSEMMSNPPVR 391
             P        P   T  P    +   P  T P+P +      P ST  +      +PP  
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646

Query: 392  ATAS---GVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKT-VPASGAMTT-SLMTVPS 446
             T +       +PP     S  ++T     P +   S +  T  P +  MTT S  T PS
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706

Query: 447  SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPT 506
            S + +T   S+T +           +    P+     +       T+S   +TPL  + T
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSIT 1766

Query: 507  SGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQ 566
                S  P + T   T  +P                 P  +     ++     G   AA 
Sbjct: 1767 PPTFS--PFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDT----ELIGDVCGPGWAAN 1820

Query: 567  MKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGT 626
            +    +     P+      G     ++ D + G++ C        G +      P A   
Sbjct: 1821 ISCRATMYPDVPI------GQLGQTVVCDVSVGLI-CKNEDQKPGGVI------PMAFCL 1867

Query: 627  MFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTA 686
             +   +        PT +   T     + P  T   +          T +   +T+ +T 
Sbjct: 1868 NYEINVQCCECVTQPTTMTTTTTENP-TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1926

Query: 687  TVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQM 746
            T +   +      Q P   P   +    +      P  TQ P    ++   ++T      
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----- 1978

Query: 747  NSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEI 806
             +PT     TPT    T+ T  TP   T  P    +  T   ++     P    P     
Sbjct: 1979 -TPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP---TPTPTGT 2031

Query: 807  ATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAP 866
             TP  +P     +   +T T +   +  P    PI+   +  +T +    G   P     
Sbjct: 2032 QTPTTTP---ITTTTTVTPTPTPTGTQTP-TTTPIT--TTTTVTPTPTPTGTQTPTTTPI 2085

Query: 867  DSRVTSTSQMMPTASGDMCTLPVR-------APASGGVSSPLVRAPASGTMSTPLRRPSA 919
             +  T T    PT +    T P+         P   G  +P      + T  TP   P+ 
Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
             +T +T  +        +T  T      G   P        T P+   + +         
Sbjct: 2146 TQTPTTTPITT------TTTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGT 2192

Query: 980  METMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGS 1039
                 +  T+T   +   + + + + TT  ++      P          T+    + +  
Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2252

Query: 1040 MPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKA 1099
             P P P  T +        P  T   +    TP    +G  T +T         TP    
Sbjct: 2253 TPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304

Query: 1100 TDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
            T +   +T+ I  T + + PT   T T   T  P
Sbjct: 2305 TGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTP 2337



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 187/937 (19%), Positives = 308/937 (32%), Gaps = 105/937 (11%)

Query: 282  SPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKP-- 339
            SP PTST       TP      +         SP     +TP  +   +  +ST   P  
Sbjct: 1407 SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPP 1466

Query: 340  --APDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASG- 396
               P     +P+  T  PS    T T P P +    P +T        +  P   T S  
Sbjct: 1467 TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP 1526

Query: 397  --VMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQ 454
                + PP     S   +TP+   P +   +    T P+    TT+  T P +   S   
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPI--TPPTSTTTLPPTTTPSPPPTTTT--TPPPTTTPSPPT 1582

Query: 455  MSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQP 514
             +  +   ++       T+ + PT +           T S   +TP+   PTS   +T P
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT---TTPSPPTTTPIT-PPTS--TTTLP 1636

Query: 515  VTATASE----TMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAM 570
             T T S     T + P  T P+  + +      P++   + P   T +S +T+       
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPS--PPITTTTTPPPTTTPSSPITTTPSPPTT 1694

Query: 571  T------SGAMSTPLMTAQTSGSTSTLLMRDTASGVMS--------CPQMRSLASGALSK 616
            T      +   S+P+ T  T  ST+T     T     S           M +L     S 
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754

Query: 617  PLMT----PKASGTMFTEKMTTTASEAMPTLL----MRDTVSGALSMPQ-----MTDTAS 663
            PL T    P  +   F+   TTT +     L       D+       P      + D   
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814

Query: 664  GGLSASLM-RDTASGAMSTSQMTATVSGGMSMPLM---RAQDPG-VMP-ASLMRAKVSGK 717
             G +A++  R T    +   Q+  TV   +S+ L+     Q PG V+P A  +  +++ +
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874

Query: 718  M---LSQPMS-----TQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMST 769
                ++QP +     T++P   + +P+ + T       +PT     TPT    T+ T  T
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVT 1931

Query: 770  PLMR-------TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQ 822
            P          T+ P    + +T   +      P      +    TP  +P  G  +   
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTT 1990

Query: 823  MTATASGMMSSMP-----QVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMM 877
               T +  ++  P     Q         +  +T +    G   P      +  T T    
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 878  PTASGDMCTLPVRA-------PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRA 930
            PT +    T P+         P   G  +P      + T  TP   P+  +T +T  +  
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 931  SASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATST 990
            +      T  T      G   P        T P+   + +              +  T+T
Sbjct: 2111 T------TTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157

Query: 991  LQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATAS 1050
               +   + + + + TT  ++      P          T+    + +   P P P  T +
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2217

Query: 1051 GCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHI 1110
                  + P  T T      TP    +   T  T  T      TP    T +    T+  
Sbjct: 2218 PT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273

Query: 1111 NITASGSKPTSHMTATTPETAKPPPKEVPS-FGMLTP 1146
             +T + +   +    TTP T        P+  G  TP
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2310



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 132/691 (19%), Positives = 235/691 (34%), Gaps = 93/691 (13%)

Query: 49   PIVSTSASDPGGTSTQLMT---SPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLM 105
            PI +T+   P  T T   T   +P+  T +      P +G  +P   P + +  ++P   
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPT 3775

Query: 106  PASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDF----------GTMSATL 155
            P   +G  +P   P   + T++P  + +  G  +P    I             GT + T 
Sbjct: 3776 P---TGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 156  MVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL-MLAPDSGELSPILMQDMNPG 214
                 +  ++P   P  +     TPI +T++     TP     P +  ++        P 
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 215  VMSTQP---VPAPSSEAMSPLQI-TDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISS 270
               TQ     P  ++  ++P    T   T   + +  T   +   +    +GT +   + 
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTP 3947

Query: 271  LIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDA 330
            +  +   +   +P PT TQ      TP  + + +    +   +  G++  +T     P  
Sbjct: 3948 ITTTTTVT--PTPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQTPTT----TPIT 3995

Query: 331  GEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPV 390
               +  P P P              + V PT   P P +G  +P +T    +  ++  P 
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTP-TGTQTPTTTPITTTTTVTPTP- 4050

Query: 391  RATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVM 450
              T +G  + P    + +    TP    P      T     P +  +TT+    P+    
Sbjct: 4051 --TPTGTQT-PTTTPITTTTTVTP---TPTPTGTQT-----PTTTPITTTTTVTPTPTPT 4099

Query: 451  STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL--RRAPTSG 508
             T+  + T         T   T    PTG+           T      TP   +   T+ 
Sbjct: 4100 GTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154

Query: 509  AMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
              +T  VT T + T +    T P + + ++     P       P         TS A + 
Sbjct: 4155 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH-------TSTAPIA 4207

Query: 569  AMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMF 628
             +T+        T QTS STS+ L   T         + S    A+              
Sbjct: 4208 ELTTSNPPPESSTPQTSRSTSSPLTESTT--------LLSTLPPAI-------------- 4245

Query: 629  TEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATV 688
              +MT+TA  + PT     +    LS P  T T+  G         +S A + S +  T 
Sbjct: 4246 --EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303

Query: 689  SGGMSMPLMRAQDPGVMPASLMRAKVSGKML 719
            +   +        P ++  + +R   S  ++
Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLI 4334



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 184/952 (19%), Positives = 303/952 (31%), Gaps = 113/952 (11%)

Query: 213  PGVMSTQPVPAPSSEAMSPLQITDED-TEAMSKVLMTALASGEISSLLMSGTDSEAISSL 271
            P   +T P P P+S    P   T    T   +    T   S  I++       +     +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 272  IMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAG 331
              +      T+P P +T  S    TP      +         SP +    TP  S     
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518

Query: 332  EMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVR 391
              +T   P+P     +    T  PS    T   P   +  + P +T +      + PP  
Sbjct: 1519 PTTT---PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575

Query: 392  ATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMS 451
             T S     PP     S    T     P          T P+    TT+  T P +   S
Sbjct: 1576 TTPS-----PPTTTTPSPPTITTTTPPPT---------TTPSPPTTTTT--TPPPTTTPS 1619

Query: 452  TEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMS 511
                +       +  L    T    PT             T     +TP   +P +    
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPT-----------TTTTPPPTTTP---SPPTTTTP 1665

Query: 512  TQPVTATA----SETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQM 567
            + P+T T     + T S P  T P+  + +M       + +  +    T +S  T +   
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725

Query: 568  KAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTM 627
              MT+    +P  T     +T T L   T S  ++   +          P +TP      
Sbjct: 1726 TTMTT---PSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL---------PPSITPPTFSPF 1773

Query: 628  FTEKMTTTASEAMPTLLMRDTVSGALSMP-----QMTDTASGGLSASL-MRDTASGAMST 681
             T   TT            D+       P      + D    G +A++  R T    +  
Sbjct: 1774 STTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPI 1833

Query: 682  SQMTATVSGGMSMPLM---RAQDP-GVMP-ASLMRAKVS---GKMLSQP-----MSTQDP 728
             Q+  TV   +S+ L+     Q P GV+P A  +  +++    + ++QP      +T++P
Sbjct: 1834 GQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENP 1893

Query: 729  GGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRAS 788
               + +P+ + T       +PT     TPT    T+ T  TP   T  P    +  T   
Sbjct: 1894 TPPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPI 1947

Query: 789  SSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMP 848
            ++     P    P      TP  +P     +   +T T +   +  P    PI+   +  
Sbjct: 1948 TTTTTVTP---TPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTP-TTTPIT--TTTT 1998

Query: 849  LTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVR-------APASGGVSSPL 901
            +T +    G   P      +  T T    PT +    T P+         P   G  +P 
Sbjct: 1999 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2058

Query: 902  VRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT 961
                 + T  TP   P+  +T +T  +        +T  T      G   P        T
Sbjct: 2059 TTPITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTPTPTPTGTQTPT-------T 2105

Query: 962  MPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRA 1021
             P+   + +              +  T+T   +   + + + + TT  ++      P   
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 1022 SASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGT 1081
                   T+    + +   P P P  T +        P  T   +    TP    +G  T
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2217

Query: 1082 MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP 1133
             +T         TP    T +   +T+ I  T + + PT   T T   T  P
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTP 2268



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 90/396 (22%), Positives = 130/396 (32%), Gaps = 40/396 (10%)

Query: 767  MSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTAT 826
            ++TP   T+ P   P+  T    +   S P           TP  SP     + P  T T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTT 1453

Query: 827  ASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTAS-GDMC 885
             S  +S+      P +   S P T  +       P    P    T+T+   PT +     
Sbjct: 1454 PSPPISTT--TTPPPTTTPSPPTTTPS-------PPTTTPSPPTTTTTTPPPTTTPSPPT 1504

Query: 886  TLPVRAPASGGVSSPLVRA----------PASGTMSTPLRRPSACETVSTELMRASASGH 935
            T P+  PAS     P              P + T S P   P    T +T L   +    
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564

Query: 936  MSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSV 995
              T  TT   +   S P    P+  T+             + P   T  S  T+T  T  
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITT-----------TTPPPTTTPSPPTTTTTTPP 1613

Query: 996  ANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMG 1055
              +     + T  T      T P   + S   +T+      +   P P    T S     
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT--TPSPPTTTTPSPPITT 1671

Query: 1056 MSMPQMTATDSRGMST----PLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHI- 1110
             + P  T T S  ++T    P    + P   +TP +     +TP    T S   +T    
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731

Query: 1111 NITASGSKPTSHMTATTPETAKPPPKEVPSFGMLTP 1146
            + T + S PT+ MT   P T   P    P    +TP
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 163/865 (18%), Positives = 318/865 (36%), Gaps = 71/865 (8%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
             A+   S    A +A   T TAS   S      A  +G  S   T S+A    +   +  
Sbjct: 1195 TASTAGSETTTASTAGSETTTAS--TSGSETNTACTTG--SETSTPSSAGSETNTAFIIG 1250

Query: 866  PDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE 921
             ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S   
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SIQP 1307

Query: 922  TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME 981
              +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M    
Sbjct: 1308 ITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGASS 1365

Query: 982  TMASGATSTLQTSVANSRSMSLSQT 1006
            T ++    T   S     S +  +T
Sbjct: 1366 TTSAHGVRTTTGSTREPTSSTFQET 1390



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 213/1138 (18%), Positives = 396/1138 (34%), Gaps = 112/1138 (9%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT      +  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
             +       T+     ++ A+G  +     T ++  + T   S A S +     TT + +
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEA----TTTSTEGSETTTASTAGSET-----TTASTA 1199

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS SGS        T + C  G              ST
Sbjct: 1200 GSETTT---ASTAGSETTT---ASTSGS-------ETNTACTTGSE-----------TST 1235

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 72/346 (20%), Positives = 126/346 (36%), Gaps = 28/346 (8%)

Query: 130  LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA 189
            L T+       G  T    G+ + T+ +             A + G   T + +TSS   
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT------ASTEGSEATTVSTTSSETT 1134

Query: 190  MSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA 249
             ++         E++ +         +ST    A +S A    + T   TE  S+    +
Sbjct: 1135 TASTT-----GSEMTTVFTTVSETTTVSTIGSEATTSSAAGS-EATTTSTEG-SETTTAS 1187

Query: 250  LASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSS 309
             A  E ++   +G+++   S+   S   +  TS   T+T  + G  T   S   S   ++
Sbjct: 1188 TAGSETTTASTAGSETTTASTA-GSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 310  LLMSSP---GSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVM 359
             ++ S     S     P  +     E +T+   A  A A S         L  A    + 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 360  PTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP 419
            P    P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA 
Sbjct: 1307 PITNTPM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGAS 1364

Query: 420  ASGNMSTLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
            ++ +   ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1410


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 163/865 (18%), Positives = 318/865 (36%), Gaps = 71/865 (8%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
             A+   S    A +A   T TAS   S      A  +G  S   T S+A    +   +  
Sbjct: 1195 TASTAGSETTTASTAGSETTTAS--TSGSETNTACTTG--SETSTPSSAGSETNTAFIIG 1250

Query: 866  PDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE 921
             ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S   
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SIQP 1307

Query: 922  TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME 981
              +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M    
Sbjct: 1308 ITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGASS 1365

Query: 982  TMASGATSTLQTSVANSRSMSLSQT 1006
            T ++    T   S     S +  +T
Sbjct: 1366 TTSAHGVRTTTGSTREPTSSTFQET 1390



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 213/1138 (18%), Positives = 396/1138 (34%), Gaps = 112/1138 (9%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT      +  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
             +       T+     ++ A+G  +     T ++  + T   S A S +     TT + +
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEA----TTTSTEGSETTTASTAGSET-----TTASTA 1199

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS SGS        T + C  G              ST
Sbjct: 1200 GSETTT---ASTAGSETTT---ASTSGS-------ETNTACTTGSE-----------TST 1235

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 72/346 (20%), Positives = 126/346 (36%), Gaps = 28/346 (8%)

Query: 130  LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA 189
            L T+       G  T    G+ + T+ +             A + G   T + +TSS   
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT------ASTEGSEATTVSTTSSETT 1134

Query: 190  MSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA 249
             ++         E++ +         +ST    A +S A    + T   TE  S+    +
Sbjct: 1135 TASTT-----GSEMTTVFTTVSETTTVSTIGSEATTSSAAGS-EATTTSTEG-SETTTAS 1187

Query: 250  LASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSS 309
             A  E ++   +G+++   S+   S   +  TS   T+T  + G  T   S   S   ++
Sbjct: 1188 TAGSETTTASTAGSETTTASTA-GSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 310  LLMSSP---GSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVM 359
             ++ S     S     P  +     E +T+   A  A A S         L  A    + 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 360  PTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP 419
            P    P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA 
Sbjct: 1307 PITNTPM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGAS 1364

Query: 420  ASGNMSTLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
            ++ +   ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1410


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 163/865 (18%), Positives = 318/865 (36%), Gaps = 71/865 (8%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRA 865
             A+   S    A +A   T TAS   S      A  +G  S   T S+A    +   +  
Sbjct: 1195 TASTAGSETTTASTAGSETTTAS--TSGSETNTACTTG--SETSTPSSAGSETNTAFIIG 1250

Query: 866  PDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACE 921
             ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S   
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SIQP 1307

Query: 922  TVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLME 981
              +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M    
Sbjct: 1308 ITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGASS 1365

Query: 982  TMASGATSTLQTSVANSRSMSLSQT 1006
            T ++    T   S     S +  +T
Sbjct: 1366 TTSAHGVRTTTGSTREPTSSTFQET 1390



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 213/1138 (18%), Positives = 396/1138 (34%), Gaps = 112/1138 (9%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT      +  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
             +       T+     ++ A+G  +     T ++  + T   S A S +     TT + +
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEA----TTTSTEGSETTTASTAGSET-----TTASTA 1199

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS SGS        T + C  G              ST
Sbjct: 1200 GSETTT---ASTAGSETTT---ASTSGS-------ETNTACTTGSE-----------TST 1235

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1236 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1293



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 72/346 (20%), Positives = 126/346 (36%), Gaps = 28/346 (8%)

Query: 130  LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA 189
            L T+       G  T    G+ + T+ +             A + G   T + +TSS   
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT------ASTEGSEATTVSTTSSETT 1134

Query: 190  MSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA 249
             ++         E++ +         +ST    A +S A    + T   TE  S+    +
Sbjct: 1135 TASTT-----GSEMTTVFTTVSETTTVSTIGSEATTSSAAGS-EATTTSTEG-SETTTAS 1187

Query: 250  LASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSS 309
             A  E ++   +G+++   S+   S   +  TS   T+T  + G  T   S   S   ++
Sbjct: 1188 TAGSETTTASTAGSETTTASTA-GSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 310  LLMSSP---GSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVM 359
             ++ S     S     P  +     E +T+   A  A A S         L  A    + 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 360  PTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP 419
            P    P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA 
Sbjct: 1307 PITNTPM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGAS 1364

Query: 420  ASGNMSTLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
            ++ +   ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1410


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 237/1019 (23%), Positives = 384/1019 (37%), Gaps = 203/1019 (19%)

Query: 30   RPMTETRADVQILHSHVQLPIVSTSASDPGGT--STQLMTSPVFDTMSAPLMGVPNSGAL 87
            +P+ +      ++ ++ + P+       P G   S Q    PV   + A LM   ++   
Sbjct: 999  QPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLM--VSASPA 1056

Query: 88   SPPLMPASDSGALSPLLMP--ASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTI 145
             PPL+PAS      P+L+P    +SG+L  +L   L  G LS        G   P   T+
Sbjct: 1057 GPPLIPASRPP--GPVLLPPLQPNSGSLPQVLPSPL--GVLS--------GTSRPPTPTL 1104

Query: 146  PDFGTMSATLMVAP-----DSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDS 200
                T  A + ++P      S+ + PL +P    G    P  +T++S   +T    A  +
Sbjct: 1105 SLKPTPPAPVRLSPAPPPGSSSLLKPLTVP---PGYTFPPAAATTTSTTTATATTTAVPA 1161

Query: 201  GELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLM 260
                               P PAP    +SP      D +A        L SGE+ S+  
Sbjct: 1162 -------------------PTPAPQRLILSP------DMQA-------RLPSGEVVSI-- 1187

Query: 261  SGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVM 320
                   ++SL    VA+ G S +P + Q  G   T     L    +  L +  P   + 
Sbjct: 1188 -----GQLASLAQRPVANAGGS-KPLTFQIQGNKLT-----LTGAQVRQLAVGQP-RPLQ 1235

Query: 321  STPLLSVPDAGEMSTLPKPAPDA--EAMSPALMTALPSGVMPT---QTMPAPGSGAMSPW 375
               +  V   G+   + +PA  A  +A++P      P  V+P+    T PAP +G   P 
Sbjct: 1236 RNVVHLVSAGGQHHLISQPAHVALIQAVAPT-PGPTPVSVLPSSTPSTTPAP-TGLSLPL 1293

Query: 376  STQNVDSEMMSNPPV------RATASGVMSAPPVRALDSGAMSTPLMGAPASGN----MS 425
            +   V   M++N  V      +A   G+   PP+    + A   P  G PA  N    ++
Sbjct: 1294 AANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPL----APAPRPPSSGLPAVLNPRPTLT 1349

Query: 426  TLQKTVPASGA----MTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAK---------- 471
              +   P  G     M T  +  P   ++ +     +AS   +A LT++           
Sbjct: 1350 PGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPG 1409

Query: 472  -TSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSM-PQLT 529
              S  MP  +   +A     +  S  +S PL  +      +T P  A+A  T+ +   LT
Sbjct: 1410 PASSPMPIPNSSPLA-----SPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLT 1464

Query: 530  VPASGSMSMLQMRAPVSEAM-SMPQMRTMA-SGLTSAAQMKAMTSGAMSTP-LMTAQTSG 586
            V ASG   +  +  P++  + + P   ++A SG + +A   A+T G  + P L ++QT G
Sbjct: 1465 VSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA--SALTLGLATAPSLSSSQTPG 1522

Query: 587  STSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMR 646
                LL+  T+S V   P + S  + A S  L+   A  + F        ++A   L   
Sbjct: 1523 --HPLLLAPTSSHV---PGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQA-SLLAPA 1576

Query: 647  DTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMP 706
             + S AL+ P         L+      TA  A S +   A       +P++ A  PG  P
Sbjct: 1577 SSASQALATP---------LAPMAAPQTAILAPSPAPPLA------PLPVL-APSPGAAP 1620

Query: 707  ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSET 766
              ++ +  +   +  P ST      S SP+ +                 TP +   +++T
Sbjct: 1621 --VLASSQTPVPVMAPSSTPGTSLASASPVPA----------------PTPVLAPSSTQT 1662

Query: 767  MSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTAT 826
            M         P   PS L   +S+  ++L             P  +P  G  S  Q  + 
Sbjct: 1663 ML--------PAPVPSPLPSPASTQTLAL------------APALAPTLGGSSPSQTLSL 1702

Query: 827  ASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCT 886
             +G     PQ   P       P +    +   ++ L   P    T T  + P        
Sbjct: 1703 GTG----NPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPA------- 1751

Query: 887  LPVRAPASGGVSSP---LVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTA 943
             P  APAS    +P   L  APAS + S  L  P++ +T++         G  + AQT A
Sbjct: 1752 -PPLAPASPVGPAPAHTLTLAPASSSAS--LLAPASVQTLTLSPAPVPTLG-PAAAQTLA 1807

Query: 944  MVSGGMSKPLMRA-----PASGTMPMPL-MSAMASGEMSMPLMETMASGATSTLQTSVA 996
            +       P  +A      ASG  P+P+ M +        P   T+ SG  S   T+ +
Sbjct: 1808 LAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATS 1866



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 165/695 (23%), Positives = 255/695 (36%), Gaps = 118/695 (16%)

Query: 44   SHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPL-MGVPNSGALSPPLMPASDSGALSP 102
            +HV L  +   A  PG T   ++ S    T  AP  + +P +    PP M  +++G +  
Sbjct: 1255 AHVAL--IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTM-VNNTGVVKI 1311

Query: 103  LLMPASDSGALS-PLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATL------ 155
            ++  A   G    P L PA    +       +    ++PG +  P  GT  A +      
Sbjct: 1312 VVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV 1371

Query: 156  -----MVAPDSAEISPLA-------------------------MPAPSSGVVCTPIMST- 184
                 +V   S E+S  A                         MP P+S  + +P+ ST 
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV 1431

Query: 185  ----SSSEAMSTPLML-APDSGEL-----SPILMQDMNPGVMS--TQPVPAPSSEAMSPL 232
                SSS  +S P  L AP S  L     +P+ +    P +++  T P+      A  P 
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491

Query: 233  QITDEDTEAMSKVLMTALASGEISS--------LLMSGTDSE--AISSLIMSAV------ 276
             +        +  L   LA+    S        LL++ T S    ++S +  A       
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551

Query: 277  ASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTL 336
            AS   SP P++       P P  + L       L  +S  S+ ++TPL  +         
Sbjct: 1552 ASALASPFPSAPN-----PAPAQASL-------LAPASSASQALATPLAPMAAPQTAILA 1599

Query: 337  PKPAPDAE-----AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVR 391
            P PAP        A SP     L S   P   M AP S   +P ++    S + +  PV 
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVM-APSS---TPGTSLASASPVPAPTPVL 1655

Query: 392  ATAS--GVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGV 449
            A +S   ++ AP    L S A +  L  APA     TL  + P   + T SL T    G 
Sbjct: 1656 APSSTQTMLPAPVPSPLPSPASTQTLALAPALA--PTLGGSSP---SQTLSLGTGNPQGP 1710

Query: 450  MSTEQMSATASRVM----SAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
              T+ +S T +  +    +  L++A      PT ++ ++A     A AS     P     
Sbjct: 1711 FPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTL-SLAPAPPLAPASPVGPAPAHTLT 1769

Query: 506  TSGAMSTQPVTATAS-ETMSMPQLTVPASGSMSMLQMR-APVSEAMSMPQMRTMASGLTS 563
             + A S+  + A AS +T+++    VP  G  +   +  AP S      Q    AS L  
Sbjct: 1770 LAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQ----ASSLVV 1825

Query: 564  AAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKA 623
            +A   A     M + L  ++    T TL      SG  S P   +   G   +    P  
Sbjct: 1826 SASGAAPLPVTMVSRLPVSKDEPDTLTL-----RSGPPSPPSTATSFGGPRPRRQPPPPP 1880

Query: 624  SGTMF----TEKMTTTASEAMPTLLMRDTVSGALS 654
                +     EK     SE +  +       GAL+
Sbjct: 1881 RSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALA 1915



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 171/839 (20%), Positives = 308/839 (36%), Gaps = 128/839 (15%)

Query: 332  EMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVR 391
            +++ + +P P  E  +  ++    + + P    P PG    +  +   V   + ++  V 
Sbjct: 993  KVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVS 1052

Query: 392  ATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMS 451
            A+ +G    PP+  + +     P++  P   N  +L + +P+           P   +  
Sbjct: 1053 ASPAG----PPL--IPASRPPGPVLLPPLQPNSGSLPQVLPS-----------PLGVLSG 1095

Query: 452  TEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMS 511
            T +       +        + S A P GS   +    K  T       P    P + A +
Sbjct: 1096 TSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLL----KPLTVP-----PGYTFPPAAATT 1146

Query: 512  TQPVTATASETMSMPQLTVPASGSMSM-LQMRAPVSEAMSMPQMRTMASGLTSAAQMKAM 570
            T   TATA+ T        P    +S  +Q R P  E +S+ Q       L S AQ    
Sbjct: 1147 TSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQ-------LASLAQRPVA 1199

Query: 571  TSGAMSTPLMTAQTSGSTSTLL---MRDTASGVMSCPQMRSLASGALSKPLMTPKASGTM 627
             +G  S PL T Q  G+  TL    +R  A G     Q R L    +   L++      +
Sbjct: 1200 NAGG-SKPL-TFQIQGNKLTLTGAQVRQLAVG-----QPRPLQRNVVH--LVSAGGQHHL 1250

Query: 628  FTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTAT 687
             ++       +A+        VS   S    T  A  GLS  L  +     M  +     
Sbjct: 1251 ISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNN----- 1305

Query: 688  VSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMN 747
             +G + + + +A   G+ P   +          +P S+  P    ++P  ++T G  ++ 
Sbjct: 1306 -TGVVKIVVRQAPRDGLTPVPPLAPA------PRPPSSGLPA--VLNPRPTLTPG--RLP 1354

Query: 748  SPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIA 807
            +PT      P         M TP +       RP L    S S E+S     A A G   
Sbjct: 1355 TPTLGTARAP---------MPTPTL------VRPLLKLVHSPSPEVS-----ASAPGAAP 1394

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPD 867
              + SP +   S P   ++   + +S P + +P+S  +S+PL+ S       +P+     
Sbjct: 1395 LTISSPLHVPSSLPGPASSPMPIPNSSP-LASPVSSTVSVPLSSS-------LPI----- 1441

Query: 868  SRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTEL 927
                S    +P  +    T+P+ AP +   S P +    +  ++  +       +++   
Sbjct: 1442 ----SVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSG 1497

Query: 928  MRASASGHMSTAQTTAMVSGGMS--KPLMRAPASGTMP----------MPLM---SAMAS 972
               SAS       T   +S   +   PL+ AP S  +P           P++   SA+AS
Sbjct: 1498 ASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALAS 1557

Query: 973  GEMSMP-------LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASG 1025
               S P        +   AS A+  L T +A   +   +    + +  +A  P+ A + G
Sbjct: 1558 PFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPG 1617

Query: 1026 ARSTSFMRASVSGSMPMPLPRAT-ASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMST 1084
            A     + AS    +P+  P +T  +       +P  T   +   +  ++ A  P  + +
Sbjct: 1618 AAP---VLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674

Query: 1085 PQTAFGVMSTPEIKATDSGEASTSHINI---TASGSKPTSHMTATTPETAKPPPKEVPS 1140
            P +   +   P +  T  G + +  +++      G  PT  ++ T   +  P P +  S
Sbjct: 1675 PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLS 1733



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 121/508 (23%), Positives = 193/508 (37%), Gaps = 64/508 (12%)

Query: 702  PGVMPASLMRAKVSGKMLSQPM--STQDPGGMSMSPMKSMTAGGMQMNSPTSDVMS---- 755
            P V+PASLM   VS      P+  +++ PG + + P++  +    Q+      V+S    
Sbjct: 1042 PQVLPASLM---VSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSR 1098

Query: 756  --TPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSP 813
              TPT+    +      L     PG    L       G    P      S   AT   + 
Sbjct: 1099 PPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTA 1158

Query: 814  AYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPL-MRAPDSRVTS 872
                  APQ    +  M + +P  +    G ++    R  A+ G S PL  +   +++T 
Sbjct: 1159 VPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTL 1218

Query: 873  T-SQMMPTASGDMCTLP---VRAPASGG----VSSP----LVRAPASGTMSTPLR-RPSA 919
            T +Q+   A G    L    V   ++GG    +S P    L++A A     TP+   PS+
Sbjct: 1219 TGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSS 1278

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMR-APASGTMPM-PLMSAMASGEMSM 977
              + +      S     +    T + + G+ K ++R AP  G  P+ PL  A       +
Sbjct: 1279 TPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGL 1338

Query: 978  PLM----ETMASG--ATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGA----- 1026
            P +     T+  G   T TL T+ A   + +L +    +     +  + ASA GA     
Sbjct: 1339 PAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLV-HSPSPEVSASAPGAAPLTI 1397

Query: 1027 RSTSFMRASVSG--SMPMPLPRAT--ASGCGMGMSMP-----------QMTATDSRGMST 1071
             S   + +S+ G  S PMP+P ++  AS     +S+P            + A  S  ++ 
Sbjct: 1398 SSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTI 1457

Query: 1072 PL-----MRASGPG--TMSTPQTAFGVMSTPEIKATDSGEASTSHINIT---ASGSKPTS 1121
            P+     + ASGP   T  TP  A  V + P   +     AS S   +T   A+    +S
Sbjct: 1458 PISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSS 1517

Query: 1122 HMTATTPETAKPPPKEVPSFGMLTPALC 1149
              T   P    P    VP         C
Sbjct: 1518 SQTPGHPLLLAPTSSHVPGLNSTVAPAC 1545



 Score = 31.6 bits (70), Expect = 5.5
 Identities = 94/464 (20%), Positives = 164/464 (35%), Gaps = 77/464 (16%)

Query: 615  SKPLMTPKASGTMFTEKMTTTASEAM-----PTLLMRDTVSGALSMPQMTDTASGGLSAS 669
            SK    P+  GT  +E++    +E       P +    T S   + P     A   +   
Sbjct: 2382 SKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRS--TTTPPRCSPARERVPRP 2439

Query: 670  LMRDTASGAMSTSQMTATVSGGMSMPL-MRAQDP-GVMPASLMRAKVSGKML---SQPMS 724
              R   + A + + + A V   +S P+ + A +P  ++P  ++ +      +   S P  
Sbjct: 2440 APRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPAC 2499

Query: 725  TQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPS-- 782
            T  P   +  P  +       + +P+S ++  P     ++   + PL      G RP   
Sbjct: 2500 TPPPA-CTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPL------GLRPEAE 2552

Query: 783  LLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPIS 842
            L  +A +S E SL L    +S   +  L  P      A ++   +   +S  P       
Sbjct: 2553 LCAQALASPE-SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS------ 2605

Query: 843  GAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLV 902
             A S+ L   +   G       APDS   +T  ++P        LP+    S G+     
Sbjct: 2606 -APSLTLEAGSIPNGQEQ---EAPDSAEGTTLTVLPEGE----ELPLCVSESNGLE---- 2653

Query: 903  RAPASGTMSTPLRRPSACETVSTELMRAS-----------------ASGHMSTAQTTAMV 945
              P S     PL+ P   +  S EL  A                  A+   S++ T++  
Sbjct: 2654 -LPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712

Query: 946  SGGMSKPLMRAPAS------------GTMPMPLMSAMASGEMSMPLMET-------MASG 986
                ++P  R  ++            G  P P +     G +   + E           G
Sbjct: 2713 GPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRG 2772

Query: 987  ATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTS 1030
            A STL   V+ + +   S +  ++SG  ++ PI      A S+S
Sbjct: 2773 AASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSS 2816


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 227/1040 (21%), Positives = 356/1040 (34%), Gaps = 137/1040 (13%)

Query: 81   VPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSP 140
            +P S   + P   A  S        PAS  G  +P            P  +TS   V SP
Sbjct: 70   IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP------------PAKNTSPGPVSSP 117

Query: 141  GMMTIPDFGTM------SATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL 194
            G  +    GT          L ++ +       A  AP    +       +S     TP 
Sbjct: 118  GRAS----GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP- 172

Query: 195  MLAPDSGELSPILMQDMNP-GVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA---- 249
                     SP + +     G     P PAPS+    P +   +   + S+   T     
Sbjct: 173  ---------SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223

Query: 250  -----LASGEISSLLMSGTDSEA--ISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDL 302
                  A G +         S A  +SS   S  ++ GT   P         P  L +  
Sbjct: 224  ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALR 281

Query: 303  DSGIMSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQ 362
               +      ++P    +S+  L+ P        P P PD  A +P   T  PS  + T 
Sbjct: 282  PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD-NAATPLPATLPPSPPLATP 340

Query: 363  TMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASG 422
               AP S +  P S Q + S   + PP +A  S  M+ PP++A  S   + P +  P S 
Sbjct: 341  LPLAPPSPSAPP-SLQTLPSPP-ATPPSQAPPS--MTTPPMQAPPS-LQTIPPIQVPHSL 395

Query: 423  NMSTLQKTVPASGAMTTSLMTVPSSG---VMSTEQMSATASRVMSAQLTMAKTSGAMPTG 479
               +LQ   P S    +SL    S G   + +T      + R   A LT      + P  
Sbjct: 396  TSPSLQ--APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 480  SMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSML 539
            S    A     A+   + S     +P S  ++  P+ A +S     PQ   P S   S++
Sbjct: 454  SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ--APLS---SLI 508

Query: 540  QMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASG 599
                    +++ P ++T  + LT+   ++ + S A   PL TA    +T  L   +T   
Sbjct: 509  MPPLETQSSLAPPSLQTPPASLTTPP-LENLPSLA-PPPLQTASAPLTTPHL---ETPPC 563

Query: 600  VMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT 659
               CP        A   PL TP          + T   +A P          AL+ P + 
Sbjct: 564  PAPCPLQ------APPSPLTTPPPETP---SSIATPPPQAPP----------ALASPPLQ 604

Query: 660  DTASGGLSA-SLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKM 718
               S  LS  +     A   ++   + A  S   S PL     P     + +   +    
Sbjct: 605  GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 719  LSQPMS--TQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSD 776
             S P S   Q P     SP  S +A       P+   ++ P ++   S   S P+     
Sbjct: 665  FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---LAAPPLQVPPSPPASPPMS---- 717

Query: 777  PGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQ 836
                PS      +   ++ P ++ P S   + P+   A      P + A     +   P 
Sbjct: 718  ----PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773

Query: 837  VKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGG 896
               P+S     P     A     +  + +P +     +   P+AS  M  L    P +  
Sbjct: 774  ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 897  V-SSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMR 955
            V ++PL++ P S   S  L+ P    T   +    S SG     + T  ++ G   P  R
Sbjct: 834  VLAAPLLQVPPSPPASPTLQAPRRPPTPGPD---TSVSG----PRLTLALAPGPPPPPSR 886

Query: 956  APASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMA 1015
            +P+S               +S P +   +S ATST +                   G  A
Sbjct: 887  SPSS--------------TLSGPDLAGHSSSATSTPEELRGYDSGPE--------GGAAA 924

Query: 1016 TAPIRASASGARSTSFMRA-----SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS 1070
            + P  A  +     ++ R      +  G+   PLP   A+G G    +  +  T+    +
Sbjct: 925  SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 984

Query: 1071 TPLMRASGPGTMSTPQTAFG 1090
            TP   A  PG   +P T+ G
Sbjct: 985  TPAPGALDPG--PSPGTSGG 1002



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 161/719 (22%), Positives = 257/719 (35%), Gaps = 99/719 (13%)

Query: 469  MAKTSGAMPTGSMKAVAKQYKRATASGKMS-TPLRRAPTSGAMSTQPVTATASETMSMPQ 527
            +A+ +G +   ++   A +     ++G  S  P  R P SG     P    A  T   P 
Sbjct: 58   LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGP- 113

Query: 528  LTVPASGSMSMLQMRAPVSE-AMSMPQMRTMASG-LTSAAQMKAMTSGAMSTPLMTAQTS 585
              V + G  S      P+ +  + +    T+A G  T A +  A+++GA      +  T 
Sbjct: 114  --VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--SGPTP 169

Query: 586  GSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPTLLM 645
            G+ S  + R + +        R   S     P   P+ S +  +E  TT   E  P    
Sbjct: 170  GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPSPAARR 226

Query: 646  RDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVM 705
            R +  G L  P     +S     S    +   A  T +  A  S      L   + P V 
Sbjct: 227  RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286

Query: 706  PASLMRAKVSGKMLSQPMSTQDPGGMSMSPM--KSMTAGGMQMNSPTSDVMSTPTVRAWT 763
            P     A   G + S P++T  P G    P+      A  +    P S  ++TP   A  
Sbjct: 287  PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346

Query: 764  SETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQM 823
            S +    L     P   P     + +   M+ P M+AP S +   P++ P   ++++P +
Sbjct: 347  SPSAPPSLQTLPSPPATPP----SQAPPSMTTPPMQAPPSLQTIPPIQVP--HSLTSPSL 400

Query: 824  TATASGMMSSMPQVKAPISGAMSMPLTRS--TASGGMSMPLMRAPDSRVTSTSQMMPTAS 881
             A  S +  S  Q    + G+ ++  T S  T S   +   + +P SR  ST    P   
Sbjct: 401  QAPPSPLALSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTSP-SRPASTPPDSP--- 455

Query: 882  GDMCTLPVRAPASGGVSSPLVR--APASGTMSTPLRRPSACETVSTELMRASASGHMSTA 939
                  P++AP S   S PL    +PA   +S+PL       T+      +S + H   A
Sbjct: 456  ------PLQAPLSLPASPPLQTSLSPAVSPLSSPL-------TIHPLQALSSLASHSPQA 502

Query: 940  QTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSR 999
              ++++   +      AP S   P           ++ P +E + S A   LQT+     
Sbjct: 503  PLSSLIMPPLETQSSLAPPSLQTP--------PASLTTPPLENLPSLAPPPLQTA----- 549

Query: 1000 SMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMG---- 1055
            S  L+          A  P++A  S   +      S   + P   P A AS    G    
Sbjct: 550  SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609

Query: 1056 ---------------MSMPQMTATDSRGMSTPLMRASGPGTMSTP-------QTAFGVMS 1093
                           +++P + A  S   S PL   + P   +         Q  F    
Sbjct: 610  PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 1094 TPEIKATDSGEASTSHINITASGSKPTSHMTATTPETAKP----PPKEVPSFGMLTPAL 1148
            +P ++A  S  AS            P    +AT P  A P    PP +VP     +P +
Sbjct: 670  SPPVQAPFSPPAS------------PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 95/390 (24%), Positives = 132/390 (33%), Gaps = 61/390 (15%)

Query: 39   VQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPAS--D 96
            VQ   S    P VS SA+ P         S    +++AP + VP S   SPP+ P++   
Sbjct: 673  VQAPFSPPASPPVSPSATPP---------SQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723

Query: 97   SGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLM 156
              A  PL  P        P   P   S T  P +         P ++  P      +   
Sbjct: 724  PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV---------PPLLAAPPLQVPPS--- 771

Query: 157  VAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVM 216
              P S  +SPLA P P +     P ++T   +A+ +P    P     SP     M+P  +
Sbjct: 772  -PPASLPMSPLAKPPPQA----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSP--L 824

Query: 217  STQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAV 276
            +T P  AP   A   LQ+    +   S  L               G D+      +  A+
Sbjct: 825  ATPPPQAPPVLAAPLLQV--PPSPPASPTLQAPRRPP------TPGPDTSVSGPRLTLAL 876

Query: 277  ASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTP--LLSVPDAGEMS 334
            A G               P P  S   S  +S   ++   S   STP  L       E  
Sbjct: 877  APG---------------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921

Query: 335  TLPKPAPDAE--AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRA 392
                P PDAE  A  PA  +  P+  +  +  P    GA  PW              +  
Sbjct: 922  AAASPPPDAELAACHPAAWSRGPAPPLAFRGAP----GAPLPWPPATGPGSADGLCTIYE 977

Query: 393  TASGVMSAPPVRALDSGAMSTPLMGAPASG 422
            T     + P   ALD G       G  A+G
Sbjct: 978  TEGPESATPAPGALDPGPSPGTSGGKAAAG 1007


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 164/747 (21%), Positives = 258/747 (34%), Gaps = 86/747 (11%)

Query: 404  RALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVM 463
            +A    A  TP   AP            P       +L  + ++G +  + ++  A  + 
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 464  SAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETM 523
             A +         P  + +A   +  R  ASG+      RAP +   S  PV++    + 
Sbjct: 67   GATI---------PESAPRAGPTRTSRPPASGRGE----RAPPAKNTSPGPVSSPGRASG 113

Query: 524  SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASG-LTSAAQMKAMTSGAMSTPLMTA 582
            +    T P  G +    +R    E        T+A G  T A +  A+++GA      + 
Sbjct: 114  T----TRP--GPLGQKGLRISAEE--------TVARGKATEAPKRSALSAGARRDT--SG 157

Query: 583  QTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASGTMFTEKMTTTASEAMPT 642
             T G+ S  + R + +        R   S     P   P+ S +  +E  TT   E  P 
Sbjct: 158  PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPSPA 214

Query: 643  LLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDP 702
               R +  G L  P     +S     S    +   A  T +  A  S      L   + P
Sbjct: 215  ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274

Query: 703  GVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSP-------TSDVMS 755
             V P     A   G + S P++T  P   S  P  S       + SP        +  + 
Sbjct: 275  QVTPPRKDAAPALGPLSSSPLATPSP---SAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331

Query: 756  TPTVRAWTSETMSTPL--MRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSP 813
            +PT++A  S   S PL  + T  P   P+L          +LP ++AP S   + PL   
Sbjct: 332  SPTLQATHSFLPSPPLSPLATPPPQAPPAL----------ALPPLQAPPSPPASPPLSPL 381

Query: 814  AYGAMSAPQMTAT----ASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSR 869
            A  +  AP   A     A       P V+AP S   S P++ S      + P + AP  +
Sbjct: 382  ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441

Query: 870  VTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMR 929
            V  +    P  S    T P +AP       P + AP       P + P A  T   + + 
Sbjct: 442  VPPSPPASPPMS-PSATPPPQAP-------PPLAAPPLQLAKPPPQAPPALATPPLQALP 493

Query: 930  ASASGHMSTAQTTAMVSGGMS---------KPLMRAPASGTMPMPLMS--AMASGEMSMP 978
            +  +     A  +   S  MS          P++ AP     P P  S    A      P
Sbjct: 494  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553

Query: 979  LMETMASGATSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSG 1038
              +T  SG   TL  +       S S ++      +A     A+++      +      G
Sbjct: 554  GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613

Query: 1039 SMPMPLPRATASGCGMGM----SMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGV--- 1091
            +   P P A  + C          P +    + G   P   A+GPG+     T +     
Sbjct: 614  AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673

Query: 1092 -MSTPEIKATDSGEASTSHINITASGS 1117
              +TP   A D G +  +     A+G+
Sbjct: 674  ESATPAPGALDPGPSPGTSGGKAAAGA 700



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 89/388 (22%), Positives = 118/388 (30%), Gaps = 101/388 (26%)

Query: 39  VQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSG 98
           VQ   S    P VS SA+ P         S    +++AP + VP S   SPP+ P++   
Sbjct: 409 VQAPFSPPASPPVSPSATPP---------SQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459

Query: 99  ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVA 158
             +P  + A       P L  A       P L+T     +     + P     S +    
Sbjct: 460 PQAPPPLAA-------PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA--- 509

Query: 159 PDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMST 218
             S  +SPLA P P +  V            ++ PL+  P S   SP L     P     
Sbjct: 510 --SLPMSPLATPPPQAPPV------------LAAPLLQVPPSPPASPTLQAPRRP----- 550

Query: 219 QPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVAS 278
            P P P             DT      L  ALA G                         
Sbjct: 551 -PTPGP-------------DTSVSGPRLTLALAPG------------------------- 571

Query: 279 GGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTP--LLSVPDAGEMSTL 336
                           P P  S   S  +S   ++   S   STP  L       E    
Sbjct: 572 ----------------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 615

Query: 337 PKPAPDAE--AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATA 394
             P PDAE  A  PA  +  P+  +  +  P    GA  PW              +  T 
Sbjct: 616 ASPPPDAELAACHPAAWSRGPAPPLAFRGAP----GAPLPWPPATGPGSADGLCTIYETE 671

Query: 395 SGVMSAPPVRALDSGAMSTPLMGAPASG 422
               + P   ALD G       G  A+G
Sbjct: 672 GPESATPAPGALDPGPSPGTSGGKAAAG 699



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 135/600 (22%), Positives = 210/600 (35%), Gaps = 73/600 (12%)

Query: 262 GTDSEAISSLIMSAVASGGTS-PQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVM 320
           G  +EA     +SA A   TS P P       G P+P M+       + + +  P     
Sbjct: 136 GKATEAPKRSALSAGARRDTSGPTP-------GTPSPAMARRSRAAGTEVGLPRPAPSAR 188

Query: 321 STPLL-----SVPDAGEMSTL-PKPA----PDA-----EAMSPALMTALPSGVMPTQTMP 365
             P       SV  A E ST  P PA    P A        S +L ++      P ++ P
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248

Query: 366 -APGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            A G+       +Q     + +  P + T     +AP +  L S  ++TP   AP S + 
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308

Query: 425 STLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAV 484
               +T+P+  A   S  T      + +  + AT S + S  L+   T    P  +  A+
Sbjct: 309 PPSLQTLPSPPATPPSQATTS----LGSPTLQATHSFLPSPPLSPLATP---PPQAPPAL 361

Query: 485 AKQYKRATASGKMSTPLRRAPT-----SGAMSTQPVTATASETMSMP---QLTVPASGSM 536
           A    +A  S   S PL    T       A++   + A  S   S P     + PAS  +
Sbjct: 362 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 537 SMLQMRAPVSEA---MSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLM 593
           S      P S+A   ++ P ++   S   S     + T    + P + A           
Sbjct: 422 S--PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP---PLQLAKP 476

Query: 594 RDTASGVMSCPQMRSLASGALSKPLMTP-KASGTMFTEKMTTTASEAMPTLLMRDTVSGA 652
              A   ++ P +++L S   S P   P   S ++    + T   +A P L      +  
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL-----AAPL 531

Query: 653 LSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRA 712
           L +P  +  AS  L A     T     S S        G  + L  A  P   P+    +
Sbjct: 532 LQVPP-SPPASPTLQAPRRPPTPGPDTSVS--------GPRLTLALAPGPPPPPSRSPSS 582

Query: 713 KVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM 772
            +SG  L+   S+       +    S   GG   + P    ++     AW S   + PL 
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLA 641

Query: 773 RTSDPGER---PSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASG 829
               PG     P      S+ G  ++     P S        +PA GA+       T+ G
Sbjct: 642 FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA-------TPAPGALDPGPSPGTSGG 694



 Score = 38.1 bits (87), Expect = 0.059
 Identities = 92/379 (24%), Positives = 133/379 (35%), Gaps = 78/379 (20%)

Query: 49  PIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPAS 108
           P+ S + S P    T    +P   +   P        AL PP +      A +P L P S
Sbjct: 239 PLSSPARSGPSARGTP--RAPAHPSQPKP----KGLQALRPPQVTPPRKDA-APALGPLS 291

Query: 109 DSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFG--TMSATLMVAPDSAEISP 166
            S   +P    A  S +  P L T      +P        G  T+ AT    P S  +SP
Sbjct: 292 SSPLATPS-PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP-SPPLSP 349

Query: 167 LAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSS 226
           LA P P +              A++ P + AP S   SP L            P+  PS 
Sbjct: 350 LATPPPQA------------PPALALPPLQAPPSPPASPPL-----------SPLATPSP 386

Query: 227 EAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSP-QP 285
           +A + L +                        L+    S   S  + +  +   + P  P
Sbjct: 387 QAPNALAVH-----------------------LLQAPFSPPPSPPVQAPFSPPASPPVSP 423

Query: 286 TSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMS-----TPLLSVPDAGEMSTLPKPA 340
           ++T  S   P+     L       +  S P S  MS      P    P A     L KP 
Sbjct: 424 SATPPSQAPPSLAAPPL------QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477

Query: 341 PDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSA 400
           P A    PAL T  P   +P+     PG    SP  + ++    ++ PP +A    V++A
Sbjct: 478 PQA---PPALATP-PLQALPSPPASFPGQAPFSP--SASLPMSPLATPPPQAPP--VLAA 529

Query: 401 PPVRALDSGAMSTPLMGAP 419
           P ++   S   S P + AP
Sbjct: 530 PLLQVPPSPPAS-PTLQAP 547


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 160/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               +S + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1139

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1140 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1180 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1225

Query: 1072 PLMRASGPGTMSTPQTAFGVMSTPEIK--ATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T     +   + ST  ++  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1226 PSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 74/343 (21%), Positives = 127/343 (37%), Gaps = 32/343 (9%)

Query: 130  LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA 189
            L T+       G  T    G+ + T+ +             A + G   T + +TSS   
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT------ASTEGSEATTVSTTSSETT 1134

Query: 190  MSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA 249
             ++         E++ +         +ST    A +S A    + T   TE  S+    +
Sbjct: 1135 TASTT-----GSEMTTVFTTVSETTTVSTIGSEATTSSAAGS-EATTTSTEG-SETTTAS 1187

Query: 250  LASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSS 309
             A  E ++   +G+++   S+   S   +  T+   TST +S G  T     + S    S
Sbjct: 1188 TAGSETTTASTAGSETTTASTS-GSETNTACTTGSETSTPSSAGSETNTAFIIGS---ES 1243

Query: 310  LLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQ 362
             + S+   E  +T L       E +T+   A  A A S         L  A    + P  
Sbjct: 1244 TIASTASLEPTATSLTG----SETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPIT 1299

Query: 363  TMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASG 422
              P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ 
Sbjct: 1300 NTPM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTT 1357

Query: 423  NMSTLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
            +   ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1358 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 160/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               +S + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1139

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1140 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1180 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1225

Query: 1072 PLMRASGPGTMSTPQTAFGVMSTPEIK--ATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T     +   + ST  ++  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1226 PSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 74/343 (21%), Positives = 127/343 (37%), Gaps = 32/343 (9%)

Query: 130  LSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEA 189
            L T+       G  T    G+ + T+ +             A + G   T + +TSS   
Sbjct: 1081 LETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT------ASTEGSEATTVSTTSSETT 1134

Query: 190  MSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTA 249
             ++         E++ +         +ST    A +S A    + T   TE  S+    +
Sbjct: 1135 TASTT-----GSEMTTVFTTVSETTTVSTIGSEATTSSAAGS-EATTTSTEG-SETTTAS 1187

Query: 250  LASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSS 309
             A  E ++   +G+++   S+   S   +  T+   TST +S G  T     + S    S
Sbjct: 1188 TAGSETTTASTAGSETTTASTS-GSETNTACTTGSETSTPSSAGSETNTAFIIGS---ES 1243

Query: 310  LLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQ 362
             + S+   E  +T L       E +T+   A  A A S         L  A    + P  
Sbjct: 1244 TIASTASLEPTATSLTG----SETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPIT 1299

Query: 363  TMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASG 422
              P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ 
Sbjct: 1300 NTPM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTT 1357

Query: 423  NMSTLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
            +   ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1358 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 159/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRPTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1139

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1140 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1180 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1225

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1226 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 89/461 (19%), Positives = 163/461 (35%), Gaps = 46/461 (9%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL--- 103
            +L  VST+ S+    S +   +    TM +       +G+ +  +  A      + +   
Sbjct: 942  ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001

Query: 104  -LMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSA 162
                 S +G+ +  +       T++    +    V + G  T   + T S T   + + +
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS 1061

Query: 163  EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSG-ELSPILMQDMNPGVMSTQPV 221
            E + ++     +    T  + T++     +    A  +G E + + +        ST+  
Sbjct: 1062 ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1121

Query: 222  PAPSSEAMSPLQITDEDTEA-MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
             A +    S    T   T + M+ V  T   +  +S++    T S A  S   +    G 
Sbjct: 1122 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1181

Query: 281  ------TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM-------SSPGSE--------- 318
                  T+   T+T ++ G  T   S   S   ++          SS GSE         
Sbjct: 1182 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1241

Query: 319  ---VMST----PLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQTM 364
               + ST    P  +     E +T+   A  A A S         L  A    + P    
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ + 
Sbjct: 1302 PM--SGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359

Query: 425  STLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
              ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 159/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRPTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1139

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1140 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1180 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1225

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1226 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 89/461 (19%), Positives = 163/461 (35%), Gaps = 46/461 (9%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL--- 103
            +L  VST+ S+    S +   +    TM +       +G+ +  +  A      + +   
Sbjct: 942  ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001

Query: 104  -LMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSA 162
                 S +G+ +  +       T++    +    V + G  T   + T S T   + + +
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS 1061

Query: 163  EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSG-ELSPILMQDMNPGVMSTQPV 221
            E + ++     +    T  + T++     +    A  +G E + + +        ST+  
Sbjct: 1062 ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1121

Query: 222  PAPSSEAMSPLQITDEDTEA-MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
             A +    S    T   T + M+ V  T   +  +S++    T S A  S   +    G 
Sbjct: 1122 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1181

Query: 281  ------TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM-------SSPGSE--------- 318
                  T+   T+T ++ G  T   S   S   ++          SS GSE         
Sbjct: 1182 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1241

Query: 319  ---VMST----PLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQTM 364
               + ST    P  +     E +T+   A  A A S         L  A    + P    
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ + 
Sbjct: 1302 PM--SGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359

Query: 425  STLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
              ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 168/777 (21%), Positives = 286/777 (36%), Gaps = 82/777 (10%)

Query: 385  MSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTV 444
            M N   +A A      P  RA        P    P         + + A+GA+    +  
Sbjct: 1    MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60

Query: 445  PSSGVM-STEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRR 503
             + G+  +T   SA  +    +  T ++   + P  S +       + T+ G +S+P R 
Sbjct: 61   RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120

Query: 504  APTS--GAMSTQPVTATASETMSMPQLT-VPASGSMSMLQMRAPVSEAMSMPQ----MRT 556
            + T+  G +  + +  +A ET++  + T  P   ++S    R         P      R+
Sbjct: 121  SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180

Query: 557  MASGL-------TSAAQMKAMTSGAMSTPLMTAQ--TSGSTSTLLMRDTASGVMSCPQMR 607
             A+G          +A+ +  T G   +    ++  T+  +     R +A G +  P  R
Sbjct: 181  RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 608  SLASGALSKPLMTPKASGTMF--TEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGG 665
            SL+S A   PL +P  SG     T +     S+  P  L       AL  PQ+T      
Sbjct: 241  SLSSSAT--PLSSPARSGPSARGTPRAPAHPSQPKPKGLQ------ALRPPQVTPPRKDA 292

Query: 666  LSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMST 725
              A        G +S+S + AT S   ++   ++Q P  +PA+   + ++ + L+ P+  
Sbjct: 293  APAL-------GPLSSSPL-ATPSPSAAL---QSQAPPTLPATPHSSSLTCQ-LATPLPL 340

Query: 726  QDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPL--MRTSDPGERPSL 783
              P   +   ++++ +      S  +  + +PT++A  S   S PL  + T  P   P+L
Sbjct: 341  APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 784  LTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTAT----ASGMMSSMPQVKA 839
                      +LP ++AP S   + PL   A  +  AP   A     A       P V+A
Sbjct: 401  ----------ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 840  PISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSS 899
            P S   S P++ S      + P + AP  +V  +    P  S    T P +AP       
Sbjct: 451  PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAP------- 502

Query: 900  PLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMS--------- 950
            P + AP       P + P A  T   + + +  +     A  +   S  MS         
Sbjct: 503  PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562

Query: 951  KPLMRAPASGTMPMPLMS--AMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTY 1008
             P++ AP     P P  S    A      P  +T  SG   TL  +       S S ++ 
Sbjct: 563  PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622

Query: 1009 TVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGM----SMPQMTAT 1064
                 +A     A+++      +      G+   P P A  + C          P +   
Sbjct: 623  LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682

Query: 1065 DSRGMSTPLMRASGPGTMSTPQTAFGV----MSTPEIKATDSGEASTSHINITASGS 1117
             + G   P   A+GPG+     T +       +TP   A D G +  +     A+G+
Sbjct: 683  GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 739



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 161/729 (22%), Positives = 255/729 (34%), Gaps = 112/729 (15%)

Query: 277 ASGGTSPQPTSTQN-----------SGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLL 325
           ASG T P P   +                  P  S L +G        +PG+   +    
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179

Query: 326 SVPDAGEMSTLPKPAPDAEAMSP--ALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSE 383
           S   AG    LP+PAP A    P      ++ S    + T P+P +              
Sbjct: 180 SRA-AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR------------ 226

Query: 384 MMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPA--SGAMTTSL 441
                  R +A G +  P  R+L S A  TPL     SG  +      PA  S      L
Sbjct: 227 -------RPSAGGGLQRPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277

Query: 442 MTVPSSGVMSTEQMSATA-SRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTP 500
             +    V    + +A A   + S+ L     S A+ + +   +      ++ + +++TP
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337

Query: 501 LRRAPTSGA-------MSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQ 553
           L  AP S +       + + P T  +  T S+   T+ A+ S        P+S   + P 
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS---FLPSPPLSPLATPPP 394

Query: 554 MRTMASGLTSAAQMKAMTSGAMSTPLMT--AQTSGSTSTLLMRDTASGVMSCPQMRSLAS 611
               A  L       +  +    +PL T   Q   + +  L++   S   S P     + 
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 612 GALSKPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLM 671
            A   P ++P A          T  S+A P+L      +  L +P  +  AS  +S S  
Sbjct: 455 PA--SPPVSPSA----------TPPSQAPPSL-----AAPPLQVPP-SPPASPPMSPS-- 494

Query: 672 RDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGM 731
                 A    Q    ++   + PL  A+ P   P +L    +   + S P S   PG  
Sbjct: 495 ------ATPPPQAPPPLA---APPLQLAKPPPQAPPALATPPLQA-LPSPPASF--PGQA 542

Query: 732 SMSPMKSMTAGGMQMNSPTS-DVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSS 790
             SP  S+    +    P +  V++ P ++   S   S  L     P   P+     S S
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA---PRRPPTPGPDTSVS 599

Query: 791 GEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISG-----AM 845
           G     L  A A G    P RSP+   +S P +   +S   S+  +++   SG     A 
Sbjct: 600 GPR---LTLALAPGPPPPPSRSPS-STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655

Query: 846 SMPLTRSTA-------SGGMSMPL--MRAPDSRVTSTSQMMPTASGDMCTL-----PVRA 891
           S P     A       S G + PL    AP + +       P ++  +CT+     P  A
Sbjct: 656 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 715

Query: 892 PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
             + G   P    P+ GT        +     S    +A        A   ++V   +S+
Sbjct: 716 TPAPGALDP---GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSR 772

Query: 952 PLMRAPASG 960
            L+ A A G
Sbjct: 773 TLLLAAAEG 781



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 89/388 (22%), Positives = 118/388 (30%), Gaps = 101/388 (26%)

Query: 39  VQILHSHVQLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSG 98
           VQ   S    P VS SA+ P         S    +++AP + VP S   SPP+ P++   
Sbjct: 448 VQAPFSPPASPPVSPSATPP---------SQAPPSLAAPPLQVPPSPPASPPMSPSATPP 498

Query: 99  ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVA 158
             +P  + A       P L  A       P L+T     +     + P     S +    
Sbjct: 499 PQAPPPLAA-------PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA--- 548

Query: 159 PDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMST 218
             S  +SPLA P P +  V            ++ PL+  P S   SP L     P     
Sbjct: 549 --SLPMSPLATPPPQAPPV------------LAAPLLQVPPSPPASPTLQAPRRP----- 589

Query: 219 QPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVAS 278
            P P P             DT      L  ALA G                         
Sbjct: 590 -PTPGP-------------DTSVSGPRLTLALAPG------------------------- 610

Query: 279 GGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTP--LLSVPDAGEMSTL 336
                           P P  S   S  +S   ++   S   STP  L       E    
Sbjct: 611 ----------------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654

Query: 337 PKPAPDAE--AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATA 394
             P PDAE  A  PA  +  P+  +  +  P    GA  PW              +  T 
Sbjct: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAP----GAPLPWPPATGPGSADGLCTIYETE 710

Query: 395 SGVMSAPPVRALDSGAMSTPLMGAPASG 422
               + P   ALD G       G  A+G
Sbjct: 711 GPESATPAPGALDPGPSPGTSGGKAAAG 738



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 81/351 (23%), Positives = 126/351 (35%), Gaps = 62/351 (17%)

Query: 75  SAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSE 134
           +AP +G  +S  L+ P   A+      P L     S +L+  L   L     SP    S 
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351

Query: 135 YGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPL 194
             + SP     P      AT  +   + + +   +P+P    + TP     +  A++ P 
Sbjct: 352 QTLPSP-----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--PPQAPPALALPP 404

Query: 195 MLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGE 254
           + AP S   SP L            P+  PS +A + L +                    
Sbjct: 405 LQAPPSPPASPPL-----------SPLATPSPQAPNALAVH------------------- 434

Query: 255 ISSLLMSGTDSEAISSLIMSAVASGGTSP-QPTSTQNSGGIPTPLMSDLDSGIMSSLLMS 313
               L+    S   S  + +  +   + P  P++T  S   P+     L       +  S
Sbjct: 435 ----LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL------QVPPS 484

Query: 314 SPGSEVMS-----TPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPG 368
            P S  MS      P    P A     L KP P A    PAL T  P   +P+     PG
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATP-PLQALPSPPASFPG 540

Query: 369 SGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAP 419
               SP  + ++    ++ PP +A    V++AP ++   S   S P + AP
Sbjct: 541 QAPFSP--SASLPMSPLATPPPQAPP--VLAAPLLQVPPSPPAS-PTLQAP 586


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 159/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 160/873 (18%), Positives = 317/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T      S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 503  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 614

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 735  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 794

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 915  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 973  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1028

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1139

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1140 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1180 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1225

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1226 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTTTSTEGSEITTAS 726



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 89/461 (19%), Positives = 163/461 (35%), Gaps = 46/461 (9%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL--- 103
            +L  VST+ S+    S +   +    TM +       +G+ +  +  A      + +   
Sbjct: 942  ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001

Query: 104  -LMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSA 162
                 S +G+ +  +       T++    +    V + G  T   + T S T   + + +
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS 1061

Query: 163  EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSG-ELSPILMQDMNPGVMSTQPV 221
            E + ++     +    T  + T++     +    A  +G E + + +        ST+  
Sbjct: 1062 ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1121

Query: 222  PAPSSEAMSPLQITDEDTEA-MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
             A +    S    T   T + M+ V  T   +  +S++    T S A  S   +    G 
Sbjct: 1122 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1181

Query: 281  ------TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM-------SSPGSE--------- 318
                  T+   T+T ++ G  T   S   S   ++          SS GSE         
Sbjct: 1182 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1241

Query: 319  ---VMST----PLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQTM 364
               + ST    P  +     E +T+   A  A A S         L  A    + P    
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ + 
Sbjct: 1302 PM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359

Query: 425  STLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
              ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 159/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 611  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 669

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 670  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 718

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 719  TGSETTKVSTTGSETTTTSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 777

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 778  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 837

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 838  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 882

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 883  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 942

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 943  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 998

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 999  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1041

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1042 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1095

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1096 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1155

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1156 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1215

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1216 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1259

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1260 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1316

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1317 QPITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1374

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1375 SSTTSAHGVRTTTGSTREPTSSTFQET 1401



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 168/910 (18%), Positives = 330/910 (36%), Gaps = 75/910 (8%)

Query: 280  GTSPQPTSTQNSGGIPTPLMSD----LDSGIMSSLLMSSPGSE-----VMSTPLLSVPDA 330
            G+    TST +S  I    MS       +   ++   S+ GSE     + ++   +   A
Sbjct: 3    GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTA 62

Query: 331  GEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSN 387
            G  +T P P        ++S + +T   +      T+ + GSG  +        + M  +
Sbjct: 63   GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTT--------ASMAGS 114

Query: 388  PPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPAS--GAMTTSLMTVP 445
                +TA    +   +   ++  +S   MG+  + N +T  +T   S  G+ TT++ TV 
Sbjct: 115  ESTISTAGSETTTVSITGTETTMVSA--MGSETTTNSTTSSETTVTSTAGSETTTVSTVG 172

Query: 446  SSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRA 504
            S    + T     TA+    +++T   T+G+       A ++    +TA  + +T     
Sbjct: 173  SETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTG 232

Query: 505  PTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSA 564
              +   ST     TA+ TM      V  +GS + +      + A S     T  +    +
Sbjct: 233  SETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDS 292

Query: 565  AQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKAS 624
                A T+G  +T   T  +  + ++ +  +T       P+   +++ +     +    S
Sbjct: 293  KTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGS 352

Query: 625  GTM-------FTEKMTTTASEAMPTLLM-----------RDTVSGALSMPQMTDTASGGL 666
             T+        T  ++TT SE     +M            +T + +    + T  ++ G 
Sbjct: 353  ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 412

Query: 667  SASLMRDTASG----AMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQP 722
             A+ +  T S     +++ S+ T T + G  M  +         AS   ++++    S  
Sbjct: 413  EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDS 472

Query: 723  MSTQDPGGMSM--------SPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSE--TMSTPLM 772
             +T      S         S  K+    G +  + ++  + T TV    S+  T ST   
Sbjct: 473  ETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGS 532

Query: 773  RTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGM 830
             T+      S +T  S+ G    ++    +  +    T L +       +   T + +G 
Sbjct: 533  ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA 592

Query: 831  MSSMPQVK----APISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCT 886
             ++    +       S A S   T STA    +       ++   ST+    T +    +
Sbjct: 593  ETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSS 652

Query: 887  LPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACETVSTELMRASASGHMSTAQ----- 940
                A   G  ++ +    +  TM ST     +   T  +E    SA+G  +T       
Sbjct: 653  ETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSG 712

Query: 941  -TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSR 999
             TT  ++G  +  +    +  T      S + +  ++     T ++  + T   S   S 
Sbjct: 713  TTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSE 772

Query: 1000 SMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMS 1057
            + S S T    T +   ++    AS  G+ +T    AS  GS    +  A++    +   
Sbjct: 773  TTSASTTGSETTTASTTSSETTMASIMGSETT---MASTIGSETTKVSTASSKMTTVFTE 829

Query: 1058 MPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEASTSHINITASGS 1117
              + T   +    T  +  +G  T+          +T   + +++  AST     T + +
Sbjct: 830  NSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 889

Query: 1118 KPTSHMTATT 1127
            + +   TATT
Sbjct: 890  ESSETTTATT 899



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/1138 (18%), Positives = 388/1138 (34%), Gaps = 122/1138 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 228  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 287

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 288  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 343

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 344  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 403

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 404  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 463

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPL--LSVPDAGEM 333
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L   +V   G  
Sbjct: 464  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 523

Query: 334  STLPKPAPDAEAMSPALMTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRAT 393
            +T        E      ++A  S +    T  +  +   +  S     S         +T
Sbjct: 524  TT----TASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 579

Query: 394  ASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTE 453
                M+       ++   ST   G  A+    +   TV  + +  T+  T  S     T 
Sbjct: 580  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE----TT 635

Query: 454  QMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQ 513
              S T S   +A  T ++T+ A   GS           T     +   R   ++    T 
Sbjct: 636  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 695

Query: 514  PVTATASETMSMPQ----LTVPASGS-MSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568
             V+AT SET    +     TV  +GS  + +      +   S        + +T +    
Sbjct: 696  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 755

Query: 569  AMTSGAMSTPLMT-------AQTSGS----TSTLLMRDTASGVMSCPQMRSLASGALSKP 617
            A T G+ +T   T       A T+GS     ST     T + +M      +   G+ +  
Sbjct: 756  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 815

Query: 618  LMTPKAS-GTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT----------------D 660
            + T  +   T+FTE   TT +    +     + +G+ ++P  T                 
Sbjct: 816  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 875

Query: 661  TASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVS 715
            TAS   S +    T S   +T     S+ T   + G        +      AS   ++++
Sbjct: 876  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 935

Query: 716  GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM--R 773
               +S   S         S   + +  G ++ + ++    T TV A  SET +   M   
Sbjct: 936  --TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE 993

Query: 774  TSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMSS 833
            T+      S  T  S++G  +     A   G   T + S      +    T T + + S+
Sbjct: 994  TTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITST 1049

Query: 834  MPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVRA 891
                   ++ A S      T     +       ++   ST  S+    ++ D+ T  V  
Sbjct: 1050 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1109

Query: 892  PASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSK 951
              SG  ++    +  +    T  +  +A    S     ++ S   +TA TT         
Sbjct: 1110 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT--------- 1160

Query: 952  PLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTVS 1011
                                  EM+        +   ST+ +    S +     TT +  
Sbjct: 1161 --------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1200

Query: 1012 GRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMST 1071
            G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     ST
Sbjct: 1201 GSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETST 1246

Query: 1072 PLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            P    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1247 PSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1304



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 89/461 (19%), Positives = 163/461 (35%), Gaps = 46/461 (9%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL--- 103
            +L  VST+ S+    S +   +    TM +       +G+ +  +  A      + +   
Sbjct: 963  ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1022

Query: 104  -LMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSA 162
                 S +G+ +  +       T++    +    V + G  T   + T S T   + + +
Sbjct: 1023 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS 1082

Query: 163  EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSG-ELSPILMQDMNPGVMSTQPV 221
            E + ++     +    T  + T++     +    A  +G E + + +        ST+  
Sbjct: 1083 ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1142

Query: 222  PAPSSEAMSPLQITDEDTEA-MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
             A +    S    T   T + M+ V  T   +  +S++    T S A  S   +    G 
Sbjct: 1143 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1202

Query: 281  ------TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM-------SSPGSE--------- 318
                  T+   T+T ++ G  T   S   S   ++          SS GSE         
Sbjct: 1203 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1262

Query: 319  ---VMST----PLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQTM 364
               + ST    P  +     E +T+   A  A A S         L  A    + P    
Sbjct: 1263 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1322

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ + 
Sbjct: 1323 PM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1380

Query: 425  STLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
              ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1381 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1421



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 49/206 (23%), Positives = 86/206 (41%), Gaps = 21/206 (10%)

Query: 928  MRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGA 987
            M  S +   STA +  + +  MS     APA+G+      +A  +G  +  ++   +   
Sbjct: 1    MAGSEATTTSTADSKVITASSMSSETTVAPAAGS---NTTTASTTGSETTTILIKASETT 57

Query: 988  TSTLQTSVANSRSMSLSQTT-YTVSGRMATAPIRASASGARSTSFMRA-SVSGSMPMPLP 1045
            T++   S   + S + SQTT  ++SG   T     S +G+ +T+   A S + +  M   
Sbjct: 58   TASTAGSETTTPSPTGSQTTIVSISGSEITT---TSTAGSENTTVSSAGSGTTTASMAGS 114

Query: 1046 RATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTPEIKATDSGEA 1105
             +T S  G      + T     G  T ++ A G  T +         ST   + T +  A
Sbjct: 115  ESTISTAG-----SETTTVSITGTETTMVSAMGSETTTN--------STTSSETTVTSTA 161

Query: 1106 STSHINITASGSKPTSHMTATTPETA 1131
             +    ++  GS+ T+  TA +  TA
Sbjct: 162  GSETTTVSTVGSETTTAYTADSETTA 187


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 159/867 (18%), Positives = 316/867 (36%), Gaps = 85/867 (9%)

Query: 149  GTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILM 208
            G+ + T+  A DS   +     + ++    T   +T++S   S     + +  E + +  
Sbjct: 590  GSETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 209  QDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAI 268
             D    ++ST       SE       T   TE      ++A  S    S   SGT + +I
Sbjct: 649  TDSETTMVSTT-----GSER------TITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 269  SSLIMSAVASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVP 328
            +    + V++ G+    TST+ S  I T  ++  ++   S+    +  +    +   S  
Sbjct: 698  TGSETTKVSTTGSETTITSTEGSE-ITTASITGSETTTASTEGSETTTASTEGSETTSAS 756

Query: 329  DAGEMSTLPKPAPDAEAMSPAL--MTALPSGVMPTQTMPAPGSGAMSPWSTQNVDSEMMS 386
              G  +T          M+  +   T + S +    T  +  S  M+   T+N ++ + S
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 387  NPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSLMTVPS 446
                  T      +  + A  +G+ +T                T    G+ TT+  T  S
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTT---------------TTSTEGSETTTASTEGS 861

Query: 447  -SGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPLRRAP 505
             +   STE    T +  + ++ T A T G+  T +    ++    +T   +++T      
Sbjct: 862  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS 921

Query: 506  TSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAMSMPQMRTMASGLTSAA 565
             +   ST+    T + T      TV  +GS ++       +E      + TM S  T+A+
Sbjct: 922  ETTTASTEGSETTTASTEGSELTTVSTTGSETI----TVSAEGSETTTVTTMGSETTTAS 977

Query: 566  QMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALSKPLMTPKASG 625
                 T+G+ +T + TA +  +T+++   +T +              +      T   +G
Sbjct: 978  -----TAGSETTTVSTAGSETTTASIEGSETTT------------VSSTGSETTTVSTTG 1020

Query: 626  TMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMT 685
            T  T   T  +     T    +T +   +  + T T++ G       +T + + + S+ T
Sbjct: 1021 TETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG------SETTTVSTTGSETT 1074

Query: 686  ATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQ 745
               +  +    +     G   AS   ++ +   ++   +T      S +   S T+    
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 746  MNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSGEMSLPLMRAPASGE 805
              S T   M+T       + T+ST     +      S  T  S+ G  +     A +   
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194

Query: 806  IATPLRSPAYGAMSAPQMTATA--SGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLM 863
             A+   S    A ++   T TA  +G  +S P                S+A    +   +
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGSETSTP----------------SSAGSETNTAFI 1238

Query: 864  RAPDSRVTSTSQMMPTAS----GDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSA 919
               ++ + ST+ + PTA+     +  T+ + A  +   S+ +       T +T +   S 
Sbjct: 1239 IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDV---SI 1295

Query: 920  CETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL 979
                +T +     +G   TA ++  ++ GM      + AS T+P  +++    G  +M  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMD--FTASAASHTVPGIVLNTSGLGTSTMGA 1353

Query: 980  METMASGATSTLQTSVANSRSMSLSQT 1006
              T ++    T   S     S +  +T
Sbjct: 1354 SSTTSAHGVRTTTGSTREPTSSTFQET 1380



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 160/873 (18%), Positives = 318/873 (36%), Gaps = 71/873 (8%)

Query: 313  SSPGSE-----VMSTPLLSVPDAGEMSTLPKPAPDAE---AMSPALMTALPSGVMPTQTM 364
            S+ GSE     + ++   +   AG  +T P P        ++S + +T   +      T+
Sbjct: 19   STTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV 78

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
             + GSG  +        + M  +    +TA    +   +   ++  +S   MG+  + N 
Sbjct: 79   SSAGSGTTT--------ASMAGSETTVSTAGSETTTVSITGTETTMVSA--MGSETTTNS 128

Query: 425  STLQKTVPAS--GAMTTSLMTVPSSGVMS-TEQMSATASRVMSAQLTMAKTSGAMPTGSM 481
            +T  +T   S  G+ TT++ TV S    + T     TA+    +++T   T+G+      
Sbjct: 129  TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 482  KAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQM 541
             A ++    +TA  + +T       +   ST     TA+ TM      V  +GS + +  
Sbjct: 189  TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 542  RAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVM 601
                + A S     T  +    +    A T+G  +T   T  +  + ++ +  +T     
Sbjct: 249  AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 602  SCPQMRSLASGALSKPLMTPKASGTM-------FTEKMTTTASEAMPTLLM--------- 645
              P+   +++ +     +    S T+        T  ++TT SE     +M         
Sbjct: 309  IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 646  --RDTVSGALSMPQMTDTASGGLSASLMRDTASG----AMSTSQMTATVSGGMSMPLMRA 699
               +T + +    + T  ++ G  A+ +  T S     +++ S+ T T + G  M  +  
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 700  QDPGVMPASLMRAKVSGKMLSQPMSTQDPGGMSM--------SPMKSMTAGGMQMNSPTS 751
                   AS   ++++    S   +T      S         S  K+    G +  + ++
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 752  DVMSTPTVRAWTSE--TMSTPLMRTSDPGERPSLLTRASSSG--EMSLPLMRAPASGEIA 807
              + T TV    S+  T ST    T+      S +T  S+ G    ++    +  +    
Sbjct: 489  TGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST 548

Query: 808  TPLRSPAYGAMSAPQMTATASGMMSSMPQVK----APISGAMSMPLTRSTASGGMSMPLM 863
            T L +       +   T + +G  ++    +       S A S   T STA    +    
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST 608

Query: 864  RAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTM-STPLRRPSACET 922
               ++   ST+    T +    +    A   G  ++ +    +  TM ST     +   T
Sbjct: 609  ADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 923  VSTELMRASASGHMSTAQ------TTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMS 976
              +E    SA+G  +T        TT  ++G  +  +    +  T+     S + +  ++
Sbjct: 669  EGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASIT 728

Query: 977  MPLMETMASGATSTLQTSVANSRSMSLSQT--TYTVSGRMATAPIRASASGARSTSFMRA 1034
                 T ++  + T   S   S + S S T    T +   ++    AS  G+ +T    A
Sbjct: 729  GSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT---MA 785

Query: 1035 SVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMST 1094
            S  GS    +  A++    +     + T   +    T  +  +G  T+          +T
Sbjct: 786  STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT 845

Query: 1095 PEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
               + +++  AST     T + ++ +   TATT
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATT 878



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 209/1139 (18%), Positives = 391/1139 (34%), Gaps = 124/1139 (10%)

Query: 51   VSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDS 110
            VST+ S+    ST    +    TM +    V  +G+ +      S++ A S      + +
Sbjct: 207  VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTA 266

Query: 111  GALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMP 170
                     A  +G  +   ST+  G       T+    TM++T  + P++ ++S  +  
Sbjct: 267  FTEDSKTTTASTTGFETTAASTT--GSEPTMASTMGSETTMAST--IGPETTKVSTASSE 322

Query: 171  APSSGVVCTPIMSTSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMS 230
              +     +  +  S+  + +T +         + I+  + +    +       S+E   
Sbjct: 323  VTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 231  PLQITDEDTEAM------SKVLMTALASGEISSLLMSGTDSEAISSLIM---------SA 275
                + E +EA       S+    ++   E ++    G++  A+S+ +          S 
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSE 442

Query: 276  VASGGTSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLMSSPGSEVMSTPLLSVPD---AGE 332
            +    TS   T+T ++ G  T  ++   S   ++    S  +   +T L +        +
Sbjct: 443  ITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSD 502

Query: 333  MSTLPKPAPDAEAMSP--ALMTALPSGVMPTQTMPAPGSGAMS---------PWSTQNVD 381
             +T      +  A+S   + MT + +      T+   GS   +           ST+  +
Sbjct: 503  TTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSE 562

Query: 382  SEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMSTLQKTVPASGAMTTSL 441
               +S      T      +    A  +G+ +T +  A +    ++   +   S + T S 
Sbjct: 563  MTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSE 622

Query: 442  MTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKAVAKQYKRATASGKMSTPL 501
             T  S+    T   S   S   +   T ++T+    TGS + +       T +   +   
Sbjct: 623  TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSE 682

Query: 502  RRAPTSGAMSTQPVTATASETM------SMPQLTVPASGSMSMLQMRAPVSEAMSMPQMR 555
                T G+  T  V+ T SET       S   +T      ++   +    +   S     
Sbjct: 683  TTVSTEGS-GTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE 741

Query: 556  TMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALS 615
            T  +    +    A T+G+ +T   TA T+ S +T+     AS + S   M S      +
Sbjct: 742  TTTASTEGSETTSASTTGSETT---TASTTSSETTM-----ASIMGSETTMASTIGSETT 793

Query: 616  KPLMTPKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMPQMT---------------- 659
            K         T+FTE   TT +    +     + +G+ ++P  T                
Sbjct: 794  KVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 660  DTASGGLSASLMRDTASGAMST-----SQMTATVSGGMSMPLMRAQDPGVMPASLMRAKV 714
             TAS   S +    T S   +T     S+ T   + G        +      AS   +++
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI 913

Query: 715  SGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLM-- 772
            +   +S   S         S   + +  G ++ + ++    T TV A  SET +   M  
Sbjct: 914  T--TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS 971

Query: 773  RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGAMSAPQMTATASGMMS 832
             T+      S  T  S++G  +     A   G   T + S      +    T T + + S
Sbjct: 972  ETTTASTAGSETTTVSTAGSETTT---ASIEGSETTTVSSTG-SETTTVSTTGTETTITS 1027

Query: 833  SMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST--SQMMPTASGDMCTLPVR 890
            +       ++ A S      T     +       ++   ST  S+    ++ D+ T  V 
Sbjct: 1028 TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087

Query: 891  APASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMS 950
               SG  ++    +  +    T  +  +A    S     ++ S   +TA TT        
Sbjct: 1088 TSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT-------- 1139

Query: 951  KPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTLQTSVANSRSMSLSQTTYTV 1010
                                   EM+        +   ST+ +    S +     TT + 
Sbjct: 1140 ---------------------GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST 1178

Query: 1011 SGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS 1070
             G   T    AS +G+ +T+   AS +GS        TAS  G   S      T     S
Sbjct: 1179 EGSETTT---ASTAGSETTT---ASTAGS-----ETTTASTSG---SETNTACTTGSETS 1224

Query: 1071 TPLMRASGPGT--MSTPQTAFGVMSTPEIKATDSGEASTSHINITASGSKPTSHMTATT 1127
            TP    S   T  +   +T     ++ E  AT    + T+ ++ITASG+   S   ++T
Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSST 1283



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 145/751 (19%), Positives = 272/751 (36%), Gaps = 73/751 (9%)

Query: 424  MSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSGAMPTGSMKA 483
            MS+     PA+G+ TT+  T  S     T  +   AS   +A    ++T+   PTGS   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGS----ETTTILIKASETTTASTAGSETTTPSPTGSQTT 56

Query: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGS-MSMLQMR 542
            +       + SG   T    A +     +   + T + +M+  + TV  +GS  + + + 
Sbjct: 57   I------VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110

Query: 543  APVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMS 602
               +  +S     T  +  TS+      T+G+ +T + T  +  +T+     +T +   +
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 603  CPQMRSLASGALSKPLMTPKASGTMFTEKMT---------TTASEAMPTLLMRDTVSGAL 653
              +M ++ +       +TP  +G+  T   T         TT SE           + A 
Sbjct: 171  GSEMTTVFTA--GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 654  SMPQMT------------DTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRAQD 701
            +M   T             TA    +A+   D+ +    T     T +         A  
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 702  PGVMP--ASLMRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPTV 759
             G  P  AS M ++ +      P +T+     + S + ++ A G +    ++    T TV
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTK--VSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 760  RAWTSETMSTPLM--RTSDPGERPSLLTRASSSGEMSLPLMRAPASGEIATPLRSPAYGA 817
                SET +  +M   TS      S  T AS+ G  +       +     +   S     
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV 406

Query: 818  MSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTS--- 874
                  T T     S M  V   +        T + ++ G  + +    DS  T+ S   
Sbjct: 407  SITDSETTTTCTEGSEMTAVSTTVFE------TTTASTEGSEITIASTSDSETTTASTEG 460

Query: 875  ---QMMPTASGDMCTL-----PVRAPASGGVSSPLVRAPASG--TMSTPLRRPSACETVS 924
                 + TA  +  T           ++ G+ +  V    S   T ST     +A     
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520

Query: 925  TELMRASASGHMST------AQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMP 978
            +E+   S  G  +T      ++TT + + G+         S    +    A  + + +  
Sbjct: 521  SEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 979  LMETMASGA---TSTLQTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRAS 1035
               T AS A   T+T+ T+ + + + S + +  T +    +    AS + + +T+   AS
Sbjct: 581  SGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTT---AS 637

Query: 1036 VSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVMSTP 1095
              GS    +    +    +  +  + T T + G  T  + A+G  T  T  T     +T 
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET--TVSTEGSGTTTV 695

Query: 1096 EIKATDSGEASTSHINITASGSKPTSHMTAT 1126
             I  +++ + ST+    T + ++ +   TA+
Sbjct: 696  SITGSETTKVSTTGSETTITSTEGSEITTAS 726



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 89/461 (19%), Positives = 163/461 (35%), Gaps = 46/461 (9%)

Query: 47   QLPIVSTSASDPGGTSTQLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPL--- 103
            +L  VST+ S+    S +   +    TM +       +G+ +  +  A      + +   
Sbjct: 942  ELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001

Query: 104  -LMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSA 162
                 S +G+ +  +       T++    +    V + G  T   + T S T   + + +
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS 1061

Query: 163  EISPLAMPAPSSGVVCTPIMSTSSSEAMSTPLMLAPDSG-ELSPILMQDMNPGVMSTQPV 221
            E + ++     +    T  + T++     +    A  +G E + + +        ST+  
Sbjct: 1062 ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1121

Query: 222  PAPSSEAMSPLQITDEDTEA-MSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGG 280
             A +    S    T   T + M+ V  T   +  +S++    T S A  S   +    G 
Sbjct: 1122 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1181

Query: 281  ------TSPQPTSTQNSGGIPTPLMSDLDSGIMSSLLM-------SSPGSE--------- 318
                  T+   T+T ++ G  T   S   S   ++          SS GSE         
Sbjct: 1182 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1241

Query: 319  ---VMST----PLLSVPDAGEMSTLPKPAPDAEAMSPA-------LMTALPSGVMPTQTM 364
               + ST    P  +     E +T+   A  A A S         L  A    + P    
Sbjct: 1242 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1301

Query: 365  PAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM 424
            P   SG  +  +     S +   P +  TAS      P   L++  + T  MGA ++ + 
Sbjct: 1302 PM--SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359

Query: 425  STLQKTVPASGAMTTSLM--TVPSSGVMSTEQMSATASRVM 463
              ++ T  ++   T+S    T P S   +T  MS T + V+
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVI 1400


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.120    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,840,976
Number of Sequences: 37866
Number of extensions: 2567906
Number of successful extensions: 16410
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 746
Number of HSP's that attempted gapping in prelim test: 10479
Number of HSP's gapped (non-prelim): 3349
length of query: 1388
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1273
effective length of database: 13,892,928
effective search space: 17685697344
effective search space used: 17685697344
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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