Search of human proteins with 241666479

Search of human proteins with 241666479

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|241666479 hypothetical protein LOC79363 [Homo sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|241666479 hypothetical protein LOC79363 [Homo sapiens]             522   e-148
gi|124248562 rad and gem related GTP binding protein 2 [Homo sap...    57   2e-08
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa...    48   1e-05
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]           47   1e-05
gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]          45   5e-05
gi|46195789 RAB40C, member RAS oncogene family [Homo sapiens]          44   2e-04
gi|4758996 Ras-related protein Rab-33A [Homo sapiens]                  43   3e-04
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa...    42   7e-04
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]             42   7e-04
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]             42   7e-04
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]           42   7e-04
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]            41   0.001
gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo sap...    41   0.001
gi|4885263 GTP-binding mitogen-induced T-cell protein [Homo sapi...    41   0.001
gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]           40   0.002
gi|34485714 Ras-related protein Rab-23 [Homo sapiens]                  40   0.002
gi|34485716 Ras-related protein Rab-23 [Homo sapiens]                  40   0.002
gi|21703367 Di-Ras2 [Homo sapiens]                                     40   0.003
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]          39   0.003
gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]           39   0.003
gi|116812567 RAB25 [Homo sapiens]                                      38   0.008
gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens]          38   0.010
gi|11034843 ras homolog gene family, member U [Homo sapiens]           37   0.013
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]            37   0.013
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]         37   0.017
gi|73611940 RAB40A, member RAS oncogene family-like [Homo sapiens]     37   0.017
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]            37   0.022
gi|34485711 Ras-related protein Rab-27A [Homo sapiens]                 36   0.029
gi|34485709 Ras-related protein Rab-27A [Homo sapiens]                 36   0.029
gi|34485706 Ras-related protein Rab-27A [Homo sapiens]                 36   0.029

>gi|241666479 hypothetical protein LOC79363 [Homo sapiens]
          Length = 258

 Score =  522 bits (1345), Expect = e-148
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFV 60
           MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFV
Sbjct: 1   MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFV 60

Query: 61  SGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGES 120
           SGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGES
Sbjct: 61  SGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGES 120

Query: 121 ALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQY 180
           ALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQY
Sbjct: 121 ALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQY 180

Query: 181 MHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWH 240
           MHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWH
Sbjct: 181 MHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWH 240

Query: 241 QDQVAAGLLPNPPESAPE 258
           QDQVAAGLLPNPPESAPE
Sbjct: 241 QDQVAAGLLPNPPESAPE 258


>gi|124248562 rad and gem related GTP binding protein 2 [Homo
           sapiens]
          Length = 340

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 9/125 (7%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +K+ + G+SGVGK+ L     GL+    H       T   +    +     V +  ++ W
Sbjct: 115 FKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDT---YERRIMVDKEEVTLVVYDIW 171

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAP--GVVRMVI 173
           + G++     DH    C++  DAFL +FS TDR SF  +P  L R+    P   +  +++
Sbjct: 172 EQGDAGGWLRDH----CLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILV 227

Query: 174 GSKFD 178
           G+K D
Sbjct: 228 GNKSD 232


>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
           sapiens]
          Length = 216

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 47/180 (26%), Positives = 75/180 (41%), Gaps = 17/180 (9%)

Query: 52  DTASYKIFVSGKSGVGKTALVAKL-AGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMF 110
           D   +K  + G SGVGKT+L+ +   G  +P     T GI  T          +   V  
Sbjct: 19  DHVLHKTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFT------NKVVTVDGVRV 72

Query: 111 RFEFWD-CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAP-GV 168
           + + WD  G+   +   H   A   +  A L L+  T+++SF+++   L  I   A   V
Sbjct: 73  KLQIWDTAGQERFRSVTH---AYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDV 129

Query: 169 VRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRR-----LADGRTLDGRAG 223
           V M++G+K D      +   D     + + +P L   +  G       LA  + L  RAG
Sbjct: 130 VIMLLGNKADMSSERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAG 189


>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
          Length = 256

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 45/171 (26%), Positives = 70/171 (40%), Gaps = 12/171 (7%)

Query: 42  RPVLLPPVSIDTASYKIFVSGKSGVGKTALVAKLA-GLEVPVVHHETTGIQTTVVFWPAK 100
           RP L   V     ++K+ + G SGVGKT L+ +   G  +      T GI     F    
Sbjct: 50  RPSLGGGVDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGID----FRNKV 105

Query: 101 LQASSRVVMFRFEFWD-CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLA 159
           L      V  + + WD  G+   +   H   A   +  A L L+  T++ASF+++   L 
Sbjct: 106 LDVDG--VKVKLQMWDTAGQERFRSVTH---AYYRDAHALLLLYDVTNKASFDNIQAWLT 160

Query: 160 RIAGEAP-GVVRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPG 209
            I   A   V  M++G+K D      V   D     + + LP +   +  G
Sbjct: 161 EIHEYAQHDVALMLLGNKVDSAHERVVKREDGEKLAKEYGLPFMETSAKTG 211


>gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]
          Length = 229

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 41/164 (25%), Positives = 65/164 (39%), Gaps = 13/164 (7%)

Query: 46  LPPVSIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASS 105
           LPP    +  +KI V G S VGKT L  +      P     T G+     F    ++   
Sbjct: 26  LPPAR--SRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVD----FRERAVEIDG 79

Query: 106 RVVMFRFEFWD-CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGE 164
             +  + + WD  G+   +K   M+     N  A +F++  T+ ASF  LP  +      
Sbjct: 80  ERI--KIQLWDTAGQERFRK--SMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQH 135

Query: 165 --APGVVRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKS 206
             A  + R+++G+K D      VP      F     +PL    +
Sbjct: 136 LLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSA 179


>gi|46195789 RAB40C, member RAS oncogene family [Homo sapiens]
          Length = 281

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 39/190 (20%), Positives = 75/190 (39%), Gaps = 18/190 (9%)

Query: 57  KIFVSGKSGVGKTALVAKL--AGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEF 114
           K  + G S VGK  ++  L     E P  +      +TT +    +          R E 
Sbjct: 16  KFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGR--------RVRLEL 67

Query: 115 WDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIG 174
           WD   S   +F  +  +        L ++  T+R SF+ +   +  I   APGV R+++G
Sbjct: 68  WDT--SGQGRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVG 125

Query: 175 SKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGL 234
           ++        VP     A+ +   +    V       L +   ++    L+ +  + +G+
Sbjct: 126 NRLHLAFKRQVPTEQARAYAEKNCMTFFEVSP-----LCNFNVIESFTELSRIVLMRHGM 180

Query: 235 AEQLWHQDQV 244
            E++W  ++V
Sbjct: 181 -EKIWRPNRV 189


>gi|4758996 Ras-related protein Rab-33A [Homo sapiens]
          Length = 237

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 41/157 (26%), Positives = 63/157 (40%), Gaps = 17/157 (10%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGI---QTTVVFWPAKLQASSRVVMFRF 112
           +KI V G S VGKT L  +  G   P     T G+   + TV     K+         + 
Sbjct: 37  FKIIVIGDSNVGKTCLTFRFCGGTFPDKTEATIGVDFREKTVEIEGEKI---------KV 87

Query: 113 EFWD-CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA--PGVV 169
           + WD  G+   +K   M+     N  A +F++  T   SF +L   +    G A  P V 
Sbjct: 88  QVWDTAGQERFRK--SMVEHYYRNVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVP 145

Query: 170 RMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKS 206
           ++++G+K D      VP      F  A  + L    +
Sbjct: 146 KVLVGNKCDLREQIQVPSNLALKFADAHNMLLFETSA 182


>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
           family [Homo sapiens]
          Length = 327

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 43  PVLLPPVSIDTASY----KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWP 98
           P   PPVS    +Y    K+ + G SGVGKT L+ + A       +  T GI     F  
Sbjct: 116 PSPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGID----FKI 171

Query: 99  AKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQL 158
             +    + +  + + WD   +  ++F  +  A        +  +  TD  SFE++   +
Sbjct: 172 RTVDIEGKKI--KLQVWD--TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWM 227

Query: 159 ARIAGEA-PGVVRMVIGSKFD 178
             I   A  GV  +++G+K D
Sbjct: 228 KSIMENASAGVEHLLLGNKCD 248


>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 43  PVLLPPVSIDTASY----KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWP 98
           P   PPVS    +Y    K+ + G SGVGKT L+ + A       +  T GI     F  
Sbjct: 116 PSPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGID----FKI 171

Query: 99  AKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQL 158
             +    + +  + + WD   +  ++F  +  A        +  +  TD  SFE++   +
Sbjct: 172 RTVDIEGKKI--KLQVWD--TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWM 227

Query: 159 ARIAGEA-PGVVRMVIGSKFD 178
             I   A  GV  +++G+K D
Sbjct: 228 KSIMENASAGVEHLLLGNKCD 248


>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 43  PVLLPPVSIDTASY----KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWP 98
           P   PPVS    +Y    K+ + G SGVGKT L+ + A       +  T GI     F  
Sbjct: 116 PSPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGID----FKI 171

Query: 99  AKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQL 158
             +    + +  + + WD   +  ++F  +  A        +  +  TD  SFE++   +
Sbjct: 172 RTVDIEGKKI--KLQVWD--TAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWM 227

Query: 159 ARIAGEA-PGVVRMVIGSKFD 178
             I   A  GV  +++G+K D
Sbjct: 228 KSIMENASAGVEHLLLGNKCD 248


>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 35/152 (23%), Positives = 66/152 (43%), Gaps = 9/152 (5%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +KI + G +GVGKT LV +      P     T G+     F    ++ +   V  + + W
Sbjct: 10  FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVD----FMIKTVEINGEKV--KLQIW 63

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPG-VVRMVIG 174
           D   +  ++F  +  +   + +A +  +  T   SF  LP  L  I   A   V+ +++G
Sbjct: 64  D--TAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVG 121

Query: 175 SKFDQYMHTDVPERDLTAFRQAWELPLLRVKS 206
           +K D     +V ++    F +A ++  L   +
Sbjct: 122 NKIDLAERREVSQQRAEEFSEAQDMYYLETSA 153


>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 9/124 (7%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +K+ + G SGVGKT L+ + A       +  T GI     F    +    + +  + + W
Sbjct: 9   FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGID----FKIRTVDIEGKKI--KLQVW 62

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA-PGVVRMVIG 174
           D   +  ++F  +  A        + ++  TD  SFE++   +  I   A  GV R+++G
Sbjct: 63  D--TAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG 120

Query: 175 SKFD 178
           +K D
Sbjct: 121 NKCD 124


>gi|32483371 GTP-binding mitogen-induced T-cell protein [Homo
           sapiens]
          Length = 296

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/131 (29%), Positives = 61/131 (46%), Gaps = 20/131 (15%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPV-----VHHETTGIQTTVVFWPAKLQASSRVVMF 110
           Y++ + G+ GVGK+ L    AG+   +     V  E T  +T +V             + 
Sbjct: 76  YRVVLIGEQGVGKSTLANIFAGVHDSMDSDCEVLGEDTYERTLMV-------DGESATII 128

Query: 111 RFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFE---DLPGQLARIAGEAPG 167
             + W+         DH    CM+  DA+L ++S TDRASFE   +L  QL R A +   
Sbjct: 129 LLDMWENKGENEWLHDH----CMQVGDAYLIVYSITDRASFEKASELRIQLRR-ARQTED 183

Query: 168 VVRMVIGSKFD 178
           +  +++G+K D
Sbjct: 184 IPIILVGNKSD 194


>gi|4885263 GTP-binding mitogen-induced T-cell protein [Homo
           sapiens]
          Length = 296

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/131 (29%), Positives = 61/131 (46%), Gaps = 20/131 (15%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPV-----VHHETTGIQTTVVFWPAKLQASSRVVMF 110
           Y++ + G+ GVGK+ L    AG+   +     V  E T  +T +V             + 
Sbjct: 76  YRVVLIGEQGVGKSTLANIFAGVHDSMDSDCEVLGEDTYERTLMV-------DGESATII 128

Query: 111 RFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFE---DLPGQLARIAGEAPG 167
             + W+         DH    CM+  DA+L ++S TDRASFE   +L  QL R A +   
Sbjct: 129 LLDMWENKGENEWLHDH----CMQVGDAYLIVYSITDRASFEKASELRIQLRR-ARQTED 183

Query: 168 VVRMVIGSKFD 178
           +  +++G+K D
Sbjct: 184 IPIILVGNKSD 194


>gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]
          Length = 278

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/190 (19%), Positives = 74/190 (38%), Gaps = 18/190 (9%)

Query: 57  KIFVSGKSGVGKTALVAKL--AGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEF 114
           K  + G S VGK  ++A L     E P  H      +TT +    +          + + 
Sbjct: 16  KFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGR--------RVKLQL 67

Query: 115 WDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIG 174
           WD   S   +F  +  +        + ++   +R SF+ +   +  I   APGV ++++G
Sbjct: 68  WDT--SGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHAPGVPKILVG 125

Query: 175 SKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGL 234
           ++        VP     A+ +   +    V  +    + +  T      LA +  + +G+
Sbjct: 126 NRLHLAFKRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESFT-----ELARIVLLRHGM 180

Query: 235 AEQLWHQDQV 244
            ++LW   +V
Sbjct: 181 -DRLWRPSKV 189


>gi|34485714 Ras-related protein Rab-23 [Homo sapiens]
          Length = 237

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWD 116
           K+ V G   VGK++++ +         + +T G+     F   ++Q +   V  R   WD
Sbjct: 11  KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVD----FLERQIQVNDEDV--RLMLWD 64

Query: 117 CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSK 176
              +  ++FD +  A      A + +FS TDR SFE +     ++  E   +  +++ +K
Sbjct: 65  T--AGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDIPTVLVQNK 122

Query: 177 FDQYMHTDVPERDLTAFRQAWELPLLR 203
            D    + +   +  A  +  +L   R
Sbjct: 123 IDLLDDSCIKNEEAEALAKRLKLRFYR 149


>gi|34485716 Ras-related protein Rab-23 [Homo sapiens]
          Length = 237

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWD 116
           K+ V G   VGK++++ +         + +T G+     F   ++Q +   V  R   WD
Sbjct: 11  KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVD----FLERQIQVNDEDV--RLMLWD 64

Query: 117 CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSK 176
              +  ++FD +  A      A + +FS TDR SFE +     ++  E   +  +++ +K
Sbjct: 65  T--AGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEVGDIPTVLVQNK 122

Query: 177 FDQYMHTDVPERDLTAFRQAWELPLLR 203
            D    + +   +  A  +  +L   R
Sbjct: 123 IDLLDDSCIKNEEAEALAKRLKLRFYR 149


>gi|21703367 Di-Ras2 [Homo sapiens]
          Length = 199

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 12/154 (7%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           Y++ V G  GVGK++LV +     V     E+  I T    +   +     +   +    
Sbjct: 8   YRVAVFGAGGVGKSSLVLRF----VKGTFRESY-IPTVEDTYRQVISCDKSICTLQIT-- 60

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPG---QLARIAGEAPGVVRMV 172
               +   +F  M    +    AF+ ++S T R S E+L     Q+  I G+   +  M+
Sbjct: 61  --DTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIML 118

Query: 173 IGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKS 206
           +G+K D+    +V   +  A  + W+   +   +
Sbjct: 119 VGNKCDESPSREVQSSEAEALARTWKCAFMETSA 152


>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
          Length = 217

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 9/145 (6%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +KI + G S VGKT +V              T G+  TV      L    + V  + + W
Sbjct: 18  FKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTV----RSLDIDGKKV--KMQVW 71

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAG-EAPGVVRMVIG 174
           D   +  ++F  +  +   +  A +  +  T R++FE +P  +  I    A  VV M+IG
Sbjct: 72  D--TAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIG 129

Query: 175 SKFDQYMHTDVPERDLTAFRQAWEL 199
           +K D +    V   D     + + L
Sbjct: 130 NKCDLWEKRHVLFEDACTLAEKYGL 154


>gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 37/164 (22%), Positives = 67/164 (40%), Gaps = 12/164 (7%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGI---QTTVVFWPAKLQASS-RVVMFRF 112
           K+   G SGVGKT  + +    +       T GI   +  VV+       SS +      
Sbjct: 11  KLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHL 70

Query: 113 EFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA----PGV 168
           + WD   +  ++F  +  A   +   FL +F  T + SF ++   ++++   A    P +
Sbjct: 71  QLWD--TAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDI 128

Query: 169 VRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRL 212
           V  +IG+K D     +V ER        + +P     +  G+ +
Sbjct: 129 V--LIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNV 170


>gi|116812567 RAB25 [Homo sapiens]
          Length = 213

 Score = 38.1 bits (87), Expect = 0.008
 Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 15/144 (10%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQ---TTVVFWPAKLQASSRVVMFRF 112
           +K+ + G+SGVGKT L+++    E       T G++    TV+   A ++A         
Sbjct: 13  FKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKA--------- 63

Query: 113 EFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPG-VVRM 171
           + WD   + L+++  +  A        L +F  T   ++  +   L  +   A   +V M
Sbjct: 64  QIWD--TAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVM 121

Query: 172 VIGSKFDQYMHTDVPERDLTAFRQ 195
           ++G+K D     +VP  +   F +
Sbjct: 122 LVGNKSDLSQAREVPTEEARMFAE 145


>gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens]
          Length = 277

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 12/141 (8%)

Query: 57  KIFVSGKSGVGKTALVAKL--AGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEF 114
           K  + G   VGK+ ++  L     E P  H      +TT +     L    RV   + + 
Sbjct: 16  KFLLVGDRDVGKSEILESLQDGAAESPYSHLGGIDYKTTTI-----LLDGQRV---KLKL 67

Query: 115 WDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIG 174
           WD   S   +F  +  +        + ++   +R SFE +   + +I   APGV ++++G
Sbjct: 68  WDT--SGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVG 125

Query: 175 SKFDQYMHTDVPERDLTAFRQ 195
           ++        VP     A+ +
Sbjct: 126 NRLHLAFKRQVPREQAQAYAE 146


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score = 37.4 bits (85), Expect = 0.013
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 10/123 (8%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWD 116
           K  + G   VGKT+LV        P     T  I T    + A +    R V  +     
Sbjct: 51  KCVLVGDGAVGKTSLVVSYTTNGYP-----TEYIPTAFDNFSAVVSVDGRPVRLQL---- 101

Query: 117 CGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQ-LARIAGEAPGVVRMVIGS 175
           C  +   +FD +   C  NTD FL  FS    +SF+++  + +  I    P    +++G+
Sbjct: 102 CDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGT 161

Query: 176 KFD 178
           + D
Sbjct: 162 QSD 164


>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
          Length = 298

 Score = 37.4 bits (85), Expect = 0.013
 Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 11/128 (8%)

Query: 54  ASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFE 113
           A Y++ + G  GVGKT+L +  AG +   + HE  G            + ++ VV+  +E
Sbjct: 79  ALYRVVLLGDPGVGKTSLASLFAGKQERDL-HEQLGEDVYERTLTVDGEDTTLVVVDTWE 137

Query: 114 FWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFE---DLPGQLARIAGEAPGVVR 170
                +S  ++      +C++   A++ ++S  DR SFE   +L  QL R   +A  V  
Sbjct: 138 AEKLDKSWSQE------SCLQGGSAYVIVYSIADRGSFESASELRIQLRR-THQADHVPI 190

Query: 171 MVIGSKFD 178
           +++G+K D
Sbjct: 191 ILVGNKAD 198


>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 30/153 (19%), Positives = 66/153 (43%), Gaps = 9/153 (5%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +K+ + G SGVGK+ L+++    E  +    T G++    F    +Q   + +  + + W
Sbjct: 12  FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVE----FATRSIQVDGKTI--KAQIW 65

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA-PGVVRMVIG 174
           D   +  +++  +  A        L ++      ++E++   L  +   A   +V M++G
Sbjct: 66  D--TAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVG 123

Query: 175 SKFDQYMHTDVPERDLTAFRQAWELPLLRVKSV 207
           +K D      VP  +  AF +   L  +   ++
Sbjct: 124 NKSDLRHLRAVPTDEARAFAEKNNLSFIETSAL 156


>gi|73611940 RAB40A, member RAS oncogene family-like [Homo sapiens]
          Length = 278

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 12/141 (8%)

Query: 57  KIFVSGKSGVGKTALVAKLAG--LEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEF 114
           K  + G   VGK+ ++  L     E P  H      +TT +     L    RV   + + 
Sbjct: 16  KFLLVGDRDVGKSEILESLQDGTAESPYSHLGGIDYKTTTI-----LLDGQRV---KLKL 67

Query: 115 WDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIG 174
           WD   S   +F  +  +        + ++   +R SFE +   + +I   APGV ++++G
Sbjct: 68  WDT--SGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVG 125

Query: 175 SKFDQYMHTDVPERDLTAFRQ 195
           ++        VP     A+ +
Sbjct: 126 NRLHLAFKRQVPREQAQAYAE 146


>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score = 36.6 bits (83), Expect = 0.022
 Identities = 28/124 (22%), Positives = 55/124 (44%), Gaps = 9/124 (7%)

Query: 56  YKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFW 115
           +K+ + G SGVGKT L+ + +          T GI     F    ++   + +  + + W
Sbjct: 9   FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGID----FKIRTIELDGKKI--KLQIW 62

Query: 116 DCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPG-VVRMVIG 174
           D   +  ++F  +  A        + ++  T+  SF+++   +  I   A   V RM++G
Sbjct: 63  D--TAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILG 120

Query: 175 SKFD 178
           +K D
Sbjct: 121 NKCD 124


>gi|34485711 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 12/165 (7%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGI---QTTVVFWPAKLQ-ASSRVVMFRF 112
           K    G SGVGKT+++ +    +       T GI   +  VV+  +    A+ R      
Sbjct: 11  KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70

Query: 113 EFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA----PGV 168
           + WD   +  ++F  +  A   +   FL LF  T+  SF ++   ++++   A    P +
Sbjct: 71  QLWD--TAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDI 128

Query: 169 VRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLA 213
           V  + G+K D      V E +  A  + + +P     +  G  ++
Sbjct: 129 V--LCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNIS 171


>gi|34485709 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 12/165 (7%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGI---QTTVVFWPAKLQ-ASSRVVMFRF 112
           K    G SGVGKT+++ +    +       T GI   +  VV+  +    A+ R      
Sbjct: 11  KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70

Query: 113 EFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA----PGV 168
           + WD   +  ++F  +  A   +   FL LF  T+  SF ++   ++++   A    P +
Sbjct: 71  QLWD--TAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDI 128

Query: 169 VRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLA 213
           V  + G+K D      V E +  A  + + +P     +  G  ++
Sbjct: 129 V--LCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNIS 171


>gi|34485706 Ras-related protein Rab-27A [Homo sapiens]
          Length = 221

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 12/165 (7%)

Query: 57  KIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGI---QTTVVFWPAKLQ-ASSRVVMFRF 112
           K    G SGVGKT+++ +    +       T GI   +  VV+  +    A+ R      
Sbjct: 11  KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70

Query: 113 EFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEA----PGV 168
           + WD   +  ++F  +  A   +   FL LF  T+  SF ++   ++++   A    P +
Sbjct: 71  QLWD--TAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDI 128

Query: 169 VRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLA 213
           V  + G+K D      V E +  A  + + +P     +  G  ++
Sbjct: 129 V--LCGNKSDLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNIS 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,332,979
Number of Sequences: 37866
Number of extensions: 416603
Number of successful extensions: 1086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 1043
Number of HSP's gapped (non-prelim): 122
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.