Guide to the Human Genome
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Search of human proteins with 24111250

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24111250 guanine nucleotide binding protein (G protein),
alpha 13 [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24111250 guanine nucleotide binding protein (G protein), alph...   756   0.0  
gi|42476111 guanine nucleotide binding protein (G protein) alpha...   476   e-134
gi|40254462 guanine nucleotide binding protein (G protein), q po...   318   4e-87
gi|4758444 G alpha 14 [Homo sapiens]                                  314   9e-86
gi|115511049 guanine nucleotide binding protein (G protein), alp...   308   5e-84
gi|156104883 guanine nucleotide binding protein (G protein), alp...   286   2e-77
gi|10567816 guanine nucleotide binding protein, alpha activating...   281   5e-76
gi|162461738 guanine nucleotide binding protein, alpha activatin...   279   3e-75
gi|33946324 guanine nucleotide binding protein (G protein), alph...   271   9e-73
gi|4504041 guanine nucleotide binding protein (G protein), alpha...   268   8e-72
gi|5729850 guanine nucleotide binding protein (G protein), alpha...   264   9e-71
gi|4504051 guanine nucleotide binding protein, alpha z polypepti...   261   6e-70
gi|20330805 guanine nucleotide binding protein, alpha transducin...   260   2e-69
gi|22027522 rod-type transducin alpha subunit [Homo sapiens]          259   2e-69
gi|22027520 rod-type transducin alpha subunit [Homo sapiens]          259   2e-69
gi|156139155 guanine nucleotide binding protein, alpha transduci...   259   2e-69
gi|117938765 GNAS complex locus isoform g [Homo sapiens]              234   1e-61
gi|18426900 GNAS complex locus GNASS [Homo sapiens]                   232   4e-61
gi|4504043 guanine nucleotide binding protein (G protein), alpha...   229   3e-60
gi|215272301 guanine nucleotide binding protein (G protein), alp...   229   3e-60
gi|4504047 GNAS complex locus GNASL [Homo sapiens]                    229   4e-60
gi|117938762 GNAS complex locus isoform f [Homo sapiens]              228   5e-60
gi|117938759 GNAS complex locus XLas [Homo sapiens]                   226   2e-59
gi|33695153 guanine nucleotide binding protein (G protein), alph...   225   6e-59
gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]                    50   3e-06
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    45   1e-04
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    45   1e-04
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    45   1e-04
gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]                    43   4e-04
gi|4502205 ADP-ribosylation factor 4 [Homo sapiens]                    42   7e-04

>gi|24111250 guanine nucleotide binding protein (G protein), alpha
           13 [Homo sapiens]
          Length = 377

 Score =  756 bits (1951), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESG 60
           MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESG
Sbjct: 1   MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESG 60

Query: 61  KSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGD 120
           KSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGD
Sbjct: 61  KSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGD 120

Query: 121 KMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDN 180
           KMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDN
Sbjct: 121 KMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDN 180

Query: 181 LDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSV 240
           LDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSV
Sbjct: 181 LDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSV 240

Query: 241 TSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKV 300
           TSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKV
Sbjct: 241 TSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKV 300

Query: 301 QIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFR 360
           QIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFR
Sbjct: 301 QIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFR 360

Query: 361 DVKDTILHDNLKQLMLQ 377
           DVKDTILHDNLKQLMLQ
Sbjct: 361 DVKDTILHDNLKQLMLQ 377


>gi|42476111 guanine nucleotide binding protein (G protein) alpha 12
           [Homo sapiens]
          Length = 381

 Score =  476 bits (1226), Expect = e-134
 Identities = 236/354 (66%), Positives = 293/354 (82%), Gaps = 5/354 (1%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E E +R+S++ID  L+RE+  V+RLVKILLLGAGESGKSTFLKQMRIIHG++FDQ+A  E
Sbjct: 33  EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLE 92

Query: 84  FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143
           FR TI+ N++KG RVLVDAR+KL IPW  + N++HG  +M+F+ +A +     VE   F 
Sbjct: 93  FRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLP----VEPATFQ 148

Query: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203
            Y+PA+ ALW DSGI+ A+ RR EFQLGESVKYFLDNLD++G+ +Y PS+QDILLAR+ T
Sbjct: 149 LYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKAT 208

Query: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263
           KGI E+DF IK +PFKMVDVGGQRS+R++WF+CFD +TSILF+VSSSE+DQVLMEDR TN
Sbjct: 209 KGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTN 268

Query: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQ 323
           RL ES+NIFETIVNN++F NVSIILFLNK DLL EKV+ VSIK +F +F GDPH L DVQ
Sbjct: 269 RLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQ 328

Query: 324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ 377
           ++LV+CF  KRR+ + KPL+HHFTTAI+TEN+R VF  VKDTIL +NLK +MLQ
Sbjct: 329 RYLVQCFDRKRRN-RSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 381


>gi|40254462 guanine nucleotide binding protein (G protein), q
           polypeptide [Homo sapiens]
          Length = 359

 Score =  318 bits (816), Expect = 4e-87
 Identities = 164/359 (45%), Positives = 231/359 (64%), Gaps = 9/359 (2%)

Query: 18  CLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFD 77
           C L+    E +R + EI++ L R+K   +R +K+LLLG GESGKSTF+KQMRIIHG  + 
Sbjct: 9   CCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYS 68

Query: 78  QRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMV 137
              +  F   +Y N+   M+ ++ A + L IP+    N+ H   +   D     A +   
Sbjct: 69  DEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFEN-- 126

Query: 138 ETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDIL 197
                  Y+ AI++LW D GIQ  YDRRRE+QL +S KY+L++LD++ +P Y+P+QQD+L
Sbjct: 127 ------PYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL 180

Query: 198 LARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLM 257
             R PT GI EY F++++V F+MVDVGGQRSER++W  CF++VTSI+FLV+ SE+DQVL+
Sbjct: 181 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 240

Query: 258 EDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPH 317
           E    NR+ ES  +F TI+    F N S+ILFLNK DLLEEK+    + DYF E++G   
Sbjct: 241 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR 300

Query: 318 CLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
             +  ++F+++ F +   D   K +Y HFT A +TENIR VF  VKDTIL  NLK+  L
Sbjct: 301 DAQAAREFILKMFVDLNPD-SDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358


>gi|4758444 G alpha 14 [Homo sapiens]
          Length = 355

 Score =  314 bits (804), Expect = 9e-86
 Identities = 162/360 (45%), Positives = 235/360 (65%), Gaps = 11/360 (3%)

Query: 18  CLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFD 77
           C L++ E E QR S EI++ L R+K   +R +K+LLLG GESGKSTF+KQMRIIHG  + 
Sbjct: 5   CCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYS 64

Query: 78  QRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDT-RAPMAAQGM 136
              R+ F   +Y N+   M+ ++ A + L I +    N+++   +   +  +  M ++  
Sbjct: 65  DEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQ 124

Query: 137 VETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196
           VE         AI+ LW D GIQ  YDRRRE+QL +S KY+L ++D++  P ++P+QQD+
Sbjct: 125 VE---------AIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDV 175

Query: 197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVL 256
           L  R PT GI EY F+++N+ F+MVDVGGQRSER++W  CF+SVTSI+FLV+ SE+DQVL
Sbjct: 176 LRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVL 235

Query: 257 MEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDP 316
            E    NR+ ES  +F+TI+    F N S+ILFLNK DLLEEK+    +  YF E+ G  
Sbjct: 236 AECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPK 295

Query: 317 HCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
             +R  + F+++ ++++  D ++K +Y HFT A +T+NIR VF  VKDTIL  NL++  L
Sbjct: 296 QDVRAARDFILKLYQDQNPD-KEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNL 354


>gi|115511049 guanine nucleotide binding protein (G protein), alpha
           11 (Gq class) [Homo sapiens]
          Length = 359

 Score =  308 bits (789), Expect = 5e-84
 Identities = 162/359 (45%), Positives = 227/359 (63%), Gaps = 9/359 (2%)

Query: 18  CLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFD 77
           C L+    E +R + EI+K L R+K   +R +K+LLLG GESGKSTF+KQMRIIHG  + 
Sbjct: 9   CCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYS 68

Query: 78  QRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMV 137
           +  +  F   +Y N+   M+ ++ A E L I +    N+ +   +   D       +   
Sbjct: 69  EEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEH-- 126

Query: 138 ETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDIL 197
                 QY+ AI+ LW D GIQ  YDRRRE+QL +S KY+L ++D++    Y+P+QQD+L
Sbjct: 127 ------QYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL 180

Query: 198 LARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLM 257
             R PT GI EY F+++N+ F+MVDVGGQRSER++W  CF++VTSI+FLV+ SE+DQVL+
Sbjct: 181 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 240

Query: 258 EDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPH 317
           E    NR+ ES  +F TI+    F N S+ILFLNK DLLE+K+    + DYF EF+G   
Sbjct: 241 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR 300

Query: 318 CLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
             +  ++F+++ F +   D   K +Y HFT A +TENIR VF  VKDTIL  NLK+  L
Sbjct: 301 DAQAAREFILKMFVDLNPD-SDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL 358


>gi|156104883 guanine nucleotide binding protein (G protein), alpha
           15 (Gq class) [Homo sapiens]
          Length = 374

 Score =  286 bits (733), Expect = 2e-77
 Identities = 149/381 (39%), Positives = 232/381 (60%), Gaps = 20/381 (5%)

Query: 7   SRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLK 66
           +RS+   C P CL T  E    R  +EI++ L  +K   +  +K+LLLG GESGKSTF+K
Sbjct: 2   ARSLTWRCCPWCL-TEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 60

Query: 67  QMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFD 126
           QMRIIHG  + +  R+ FRP +Y N+   MR +++A E+L IP+    ++ H   +MS D
Sbjct: 61  QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 120

Query: 127 TRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGE 186
                       T    +Y  A++ LW D+GI+  Y+RRREF L +S  Y+L +L+++ E
Sbjct: 121 PYKV--------TTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITE 172

Query: 187 PDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFL 246
             Y+P+ QD+L +R PT GI+EY F ++    ++VDVGGQ+SERK+W  CF++V ++++L
Sbjct: 173 EGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYL 232

Query: 247 VSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIK 306
            S SE+DQ L E+   NR+ ESL +F TI+    F + S+ILFLNKTD+LEEK+    + 
Sbjct: 233 ASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLA 292

Query: 307 DYFLEFEGDPHCLRDVQKFLVECF-----------RNKRRDQQQKPLYHHFTTAINTENI 355
            YF  F+G        ++F+++ +              ++  + + L+ H+T A +T+NI
Sbjct: 293 TYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNI 352

Query: 356 RLVFRDVKDTILHDNLKQLML 376
           R VF+DV+D++L   L ++ L
Sbjct: 353 RKVFKDVRDSVLARYLDEINL 373


>gi|10567816 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform a [Homo sapiens]
          Length = 354

 Score =  281 bits (720), Expect = 5e-76
 Identities = 156/357 (43%), Positives = 220/357 (61%), Gaps = 10/357 (2%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC L++ E     +SK I+K L  +     + VK+LLLGAGESGKST +KQM+IIH   F
Sbjct: 2   GCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGF 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
                ++++P +YSN I+ +  +V A + L I +GD   ++  D  M  D         M
Sbjct: 62  SGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDK--ERKADAKMVCDV-----VSRM 114

Query: 137 VETRVF-LQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQD 195
            +T  F  + L A+  LW DSGIQ  ++R RE+QL +S KY+LD+LD++G  DY P++QD
Sbjct: 115 EDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQD 174

Query: 196 ILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQV 255
           IL  R  T GI E  F  KN+ F++ DVGGQRSERK+W  CF+ VT+I+F V+ S +DQV
Sbjct: 175 ILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQV 234

Query: 256 LMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGD 315
           L ED  TNR+ ESL +F++I NN+ F + SIILFLNK DL  EK++   +   F E+ G 
Sbjct: 235 LHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTG- 293

Query: 316 PHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
           P+   D   ++   F +K R    K +Y H T A +T NI++VF  V D I+ +NL+
Sbjct: 294 PNTYEDAAAYIQAQFESKNR-SPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLR 349


>gi|162461738 guanine nucleotide binding protein, alpha activating
           polypeptide O isoform b [Homo sapiens]
          Length = 354

 Score =  279 bits (714), Expect = 3e-75
 Identities = 153/357 (42%), Positives = 219/357 (61%), Gaps = 10/357 (2%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC L++ E     +SK I+K L  +     + VK+LLLGAGESGKST +KQM+IIH   F
Sbjct: 2   GCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGF 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
                ++++P +YSN I+ +  +V A + L I +GD   ++  D  M  D         M
Sbjct: 62  SGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDK--ERKADAKMVCDV-----VSRM 114

Query: 137 VETRVF-LQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQD 195
            +T  F  + L A+  LW DSGIQ  ++R RE+QL +S KY+LD+LD++G  DY P++QD
Sbjct: 115 EDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQD 174

Query: 196 ILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQV 255
           IL  R  T GI E  F  KN+ F++ DVGGQRSERK+W  CF+ VT+I+F V+ S +DQV
Sbjct: 175 ILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQV 234

Query: 256 LMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGD 315
           L ED  TNR+ ESL +F++I NN+ F++ SIILFLNK D+ EEK++   +   F E+ G 
Sbjct: 235 LHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTG- 293

Query: 316 PHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
           P    +   ++   + +K +    K +Y H T A +T NI+ VF  V D I+  NL+
Sbjct: 294 PSAFTEAVAYIQAQYESKNK-SAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLR 349


>gi|33946324 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 1 [Homo sapiens]
          Length = 354

 Score =  271 bits (692), Expect = 9e-73
 Identities = 142/356 (39%), Positives = 220/356 (61%), Gaps = 8/356 (2%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC L++ +     +SK ID+ L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGY 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
            +   ++++  +YSN I+ +  ++ A  +L I +GD++     D        A  A +G 
Sbjct: 62  SEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSAR---ADDARQLFVLAGAAEEGF 118

Query: 137 VETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196
           +   +       I+ LW DSG+Q  ++R RE+QL +S  Y+L++LD++ +P+YIP+QQD+
Sbjct: 119 MTAEL----AGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDV 174

Query: 197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVL 256
           L  R  T GI E  F  K++ FKM DVGGQRSERK+W  CF+ VT+I+F V+ S++D VL
Sbjct: 175 LRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVL 234

Query: 257 MEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDP 316
            ED   NR+ ES+ +F++I NN+ F++ SIILFLNK DL EEK++   +   + E+ G  
Sbjct: 235 AEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGS- 293

Query: 317 HCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
           +   +   ++   F +  + +  K +Y HFT A +T+N++ VF  V D I+ +NLK
Sbjct: 294 NTYEEAAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 349


>gi|4504041 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 2 [Homo sapiens]
          Length = 355

 Score =  268 bits (684), Expect = 8e-72
 Identities = 144/356 (40%), Positives = 214/356 (60%), Gaps = 7/356 (1%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC +++ +     +SK IDK L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGY 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
            +    ++R  +YSN I+ +  +V A   L I + D S      ++ +    A    QG+
Sbjct: 62  SEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAE--EQGV 119

Query: 137 VETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196
           +   +       IR LWAD G+Q  + R RE+QL +S  Y+L++L+++ + DYIP+QQD+
Sbjct: 120 LPDDLS----GVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDV 175

Query: 197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVL 256
           L  R  T GI E  F  K++ FKM DVGGQRSERK+W  CF+ VT+I+F V+ S +D VL
Sbjct: 176 LRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVL 235

Query: 257 MEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDP 316
            ED   NR+ ES+ +F++I NN+ F++ SIILFLNK DL EEK+    +   F E+ G  
Sbjct: 236 AEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTG-A 294

Query: 317 HCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
           +   +   ++   F +  + +  K +Y HFT A +T+N++ VF  V D I+ +NLK
Sbjct: 295 NKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 350


>gi|5729850 guanine nucleotide binding protein (G protein), alpha
           inhibiting activity polypeptide 3 [Homo sapiens]
          Length = 354

 Score =  264 bits (675), Expect = 9e-71
 Identities = 141/358 (39%), Positives = 215/358 (60%), Gaps = 10/358 (2%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC L++ +     +SK ID+ L  +     + VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGY 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
            +   ++++  +YSN I+ +  ++ A  +L I +G+ +           D R      G 
Sbjct: 62  SEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARAD--------DARQLFVLAGS 113

Query: 137 VETRVFLQYLPA-IRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQD 195
            E  V    L   I+ LW D G+Q  + R RE+QL +S  Y+L++LD++ + +YIP+QQD
Sbjct: 114 AEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQD 173

Query: 196 ILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQV 255
           +L  R  T GI E  F  K++ FKM DVGGQRSERK+W  CF+ VT+I+F V+ S++D V
Sbjct: 174 VLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLV 233

Query: 256 LMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGD 315
           L ED   NR+ ES+ +F++I NN+ F+  SIILFLNK DL EEK++   +   + E+ G 
Sbjct: 234 LAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGS 293

Query: 316 PHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQ 373
            +   +   ++   F +  R +  K +Y HFT A +T+N++ VF  V D I+ +NLK+
Sbjct: 294 -NTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 350


>gi|4504051 guanine nucleotide binding protein, alpha z polypeptide
           [Homo sapiens]
          Length = 355

 Score =  261 bits (668), Expect = 6e-70
 Identities = 143/360 (39%), Positives = 214/360 (59%), Gaps = 7/360 (1%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           GC  +S E E  R+S+ ID+ L  E    +R +K+LLLG   SGKST +KQM+IIH   F
Sbjct: 2   GCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGF 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
           +  A +E++P I  N I  +  ++ A   L I +  ++  +  D +  F    P  ++G 
Sbjct: 62  NLEACKEYKPLIIYNAIDSLTRIIRALAALRIDF--HNPDRAYDAVQLFALTGPAESKGE 119

Query: 137 VETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196
           +   +    L  +R LWAD G Q  + R  E+ L ++  Y+L++L+++   DYIP+ +DI
Sbjct: 120 ITPEL----LGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDI 175

Query: 197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVL 256
           L +R  T GI E  F  K + FKMVDVGGQRSERK+W  CF+ VT+I+F V  S +D  L
Sbjct: 176 LRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKL 235

Query: 257 MEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDP 316
            ED  T+R+ ESL +F++I NN  F N S+ILFLNK DLL EK++ + +   F E++G  
Sbjct: 236 YEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQ- 294

Query: 317 HCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376
           +   +   ++   F +  R+++ K +Y HFT A +T NI+ VF  V D I+ +NLK + L
Sbjct: 295 NTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGL 354


>gi|20330805 guanine nucleotide binding protein, alpha transducing
           activity polypeptide 2 [Homo sapiens]
          Length = 354

 Score =  260 bits (664), Expect = 2e-69
 Identities = 135/349 (38%), Positives = 213/349 (61%), Gaps = 8/349 (2%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           + E  ++SKE++K L  +     + VK+LLLGAGESGKST +KQM+IIH   +      E
Sbjct: 9   DKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLE 68

Query: 84  FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143
           F+  IY NV++ +  ++ A   L I + + S    G ++ +        A  + E  +  
Sbjct: 69  FKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNL-------ADSIEEGTMPP 121

Query: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203
           + +  IR LW D G+Q  ++R  E+QL +S  Y+L+ L+++ +P+Y+PS+QD+L +R  T
Sbjct: 122 ELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKT 181

Query: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263
            GI E  F +K++ F+M DVGGQRSERK+W  CF+ VT I+F  + S +D VL+ED   N
Sbjct: 182 TGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVN 241

Query: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQ 323
           R+ ESL++F +I N++ F+  SI+LFLNK DL EEK++ V +   F E++G+ +   D  
Sbjct: 242 RMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGN-NSYDDAG 300

Query: 324 KFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
            ++   F +    +  K +Y H T A +T+N++ VF  V D I+ +NLK
Sbjct: 301 NYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349


>gi|22027522 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  259 bits (663), Expect = 2e-69
 Identities = 137/351 (39%), Positives = 211/351 (60%), Gaps = 8/351 (2%)

Query: 22  SGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 81
           +G + +++ S+E++K L  +     R VK+LLLGAGESGKST +KQM+IIH   +     
Sbjct: 3   AGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEEC 62

Query: 82  EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRV 141
            EF   IY N ++ +  +V A   L+I +GD++ Q    K+M         A  + E  +
Sbjct: 63  LEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHM-------ADTIEEGTM 115

Query: 142 FLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARR 201
             +    I+ LW DSGIQ  ++R  E+QL +S  Y+L +L++L  P Y+P++QD+L +R 
Sbjct: 116 PKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRV 175

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
            T GI E  F  K++ F+M DVGGQRSERK+W  CF+ VT I+F+ + S +D VL+ED  
Sbjct: 176 KTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDE 235

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRD 321
            NR+ ESL++F +I N+R F+  SI+LFLNK D+  EK++   +   F +++G P+   D
Sbjct: 236 VNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYED 294

Query: 322 VQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
              ++   F      +  K +Y H T A +T+N++ VF  V D I+ +NLK
Sbjct: 295 AGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345


>gi|22027520 rod-type transducin alpha subunit [Homo sapiens]
          Length = 350

 Score =  259 bits (663), Expect = 2e-69
 Identities = 137/351 (39%), Positives = 211/351 (60%), Gaps = 8/351 (2%)

Query: 22  SGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 81
           +G + +++ S+E++K L  +     R VK+LLLGAGESGKST +KQM+IIH   +     
Sbjct: 3   AGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEEC 62

Query: 82  EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRV 141
            EF   IY N ++ +  +V A   L+I +GD++ Q    K+M         A  + E  +
Sbjct: 63  LEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHM-------ADTIEEGTM 115

Query: 142 FLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARR 201
             +    I+ LW DSGIQ  ++R  E+QL +S  Y+L +L++L  P Y+P++QD+L +R 
Sbjct: 116 PKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRV 175

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
            T GI E  F  K++ F+M DVGGQRSERK+W  CF+ VT I+F+ + S +D VL+ED  
Sbjct: 176 KTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDE 235

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRD 321
            NR+ ESL++F +I N+R F+  SI+LFLNK D+  EK++   +   F +++G P+   D
Sbjct: 236 VNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFFEKIKKAHLSICFPDYDG-PNTYED 294

Query: 322 VQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
              ++   F      +  K +Y H T A +T+N++ VF  V D I+ +NLK
Sbjct: 295 AGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345


>gi|156139155 guanine nucleotide binding protein, alpha transducing
           3 [Homo sapiens]
          Length = 354

 Score =  259 bits (663), Expect = 2e-69
 Identities = 139/356 (39%), Positives = 212/356 (59%), Gaps = 8/356 (2%)

Query: 17  GCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDF 76
           G  ++S   E  ++SKE++K L  +     R VK+LLLGAGESGKST +KQM+IIH   +
Sbjct: 2   GSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGY 61

Query: 77  DQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGM 136
            ++   EF+  IYSN ++ +  +V A   L I + +  + +  D+   +     +   GM
Sbjct: 62  SEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAE--DQRQLYAMANTLEDGGM 119

Query: 137 VETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDI 196
                  Q    I+ LW D GIQ  ++R  E+QL +S  Y+L++LD++    Y+P++QD+
Sbjct: 120 TP-----QLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDV 174

Query: 197 LLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVL 256
           L +R  T GI E  F  K++ F+M DVGGQRSERK+W  CF+ VT I+F  + S +D VL
Sbjct: 175 LHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVL 234

Query: 257 MEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDP 316
           +ED   NR+ ESL++F +I N++ FS  SI+LFLNK D+ +EKV  V +   F E+ G P
Sbjct: 235 VEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTG-P 293

Query: 317 HCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372
           +   D   ++   F +    ++ K +Y H T A +T+N++ VF  V D I+ +NLK
Sbjct: 294 NTFEDAGNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349


>gi|117938765 GNAS complex locus isoform g [Homo sapiens]
          Length = 379

 Score =  234 bits (596), Expect = 1e-61
 Identities = 140/369 (37%), Positives = 208/369 (56%), Gaps = 22/369 (5%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E  Q+  +K+I+K L ++K   +   ++LLLGAGESGKST +KQMRI+H   F+   +  
Sbjct: 16  EKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDEKAT 75

Query: 84  FRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143
               I +N+ + +  +V A   L +P  + +N ++      F     ++   + +     
Sbjct: 76  KVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRVDYILSVMNVPDFDFPP 129

Query: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203
           ++    +ALW D G++  Y+R  E+QL +  +YFLD +D + + DY+PS QD+L  R  T
Sbjct: 130 EFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLT 189

Query: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263
            GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+F+V+SS ++ V+ ED  TN
Sbjct: 190 SGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTN 249

Query: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFE-------- 313
           RL E+LN+F++I NNR    +S+ILFLNK DLL EKV      I+DYF EF         
Sbjct: 250 RLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDA 309

Query: 314 -----GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTIL 367
                 DP   R       E  R +      +   Y HFT A++TENIR VF D +D I 
Sbjct: 310 TPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQ 369

Query: 368 HDNLKQLML 376
             +L+Q  L
Sbjct: 370 RMHLRQYEL 378


>gi|18426900 GNAS complex locus GNASS [Homo sapiens]
          Length = 380

 Score =  232 bits (592), Expect = 4e-61
 Identities = 140/370 (37%), Positives = 210/370 (56%), Gaps = 23/370 (6%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E  Q+  +K+I+K L ++K   +   ++LLLGAGESGKST +KQMRI+H   F+  + + 
Sbjct: 16  EKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKA 75

Query: 84  FR-PTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVF 142
            +   I +N+ + +  +V A   L +P  + +N ++      F     ++   + +    
Sbjct: 76  TKVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRVDYILSVMNVPDFDFP 129

Query: 143 LQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRP 202
            ++    +ALW D G++  Y+R  E+QL +  +YFLD +D + + DY+PS QD+L  R  
Sbjct: 130 PEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVL 189

Query: 203 TKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLT 262
           T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+F+V+SS ++ V+ ED  T
Sbjct: 190 TSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQT 249

Query: 263 NRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFE------- 313
           NRL E+LN+F++I NNR    +S+ILFLNK DLL EKV      I+DYF EF        
Sbjct: 250 NRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPED 309

Query: 314 ------GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTI 366
                  DP   R       E  R +      +   Y HFT A++TENIR VF D +D I
Sbjct: 310 ATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDII 369

Query: 367 LHDNLKQLML 376
              +L+Q  L
Sbjct: 370 QRMHLRQYEL 379


>gi|4504043 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  229 bits (584), Expect = 3e-60
 Identities = 139/372 (37%), Positives = 208/372 (55%), Gaps = 28/372 (7%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E E++  +K+I+K L +E+   K   ++LLLGAGESGKST +KQMRI+H   F+   +++
Sbjct: 18  EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77

Query: 84  FRPTIYSNVIKGMRVLVDAREKL--HIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRV 141
               I  NV   +  +V A   +   +P  +  NQ   D + S    AP+      +   
Sbjct: 78  KILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI---APIT-----DFEY 129

Query: 142 FLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARR 201
             ++   ++ LW D G++  ++R  E+QL +  +YFL+ +D +   DY P+ QD+L  R 
Sbjct: 130 SQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRV 189

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
            T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+++ + S ++ V+ ED  
Sbjct: 190 LTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNN 249

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFEG----- 314
           TNRL ESL++FE+I NNR    +SIILFLNK D+L EKV      I+DYF E+       
Sbjct: 250 TNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPE 309

Query: 315 --------DPHCLRDVQKFLVECFR--NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKD 364
                   DP   R  + F+ + F   +      +   Y HFT A++TENIR VF D +D
Sbjct: 310 DATPDAGEDPKVTR-AKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368

Query: 365 TILHDNLKQLML 376
            I   +LKQ  L
Sbjct: 369 IIQRMHLKQYEL 380


>gi|215272301 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           2 [Homo sapiens]
          Length = 381

 Score =  229 bits (584), Expect = 3e-60
 Identities = 139/372 (37%), Positives = 208/372 (55%), Gaps = 28/372 (7%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E E++  +K+I+K L +E+   K   ++LLLGAGESGKST +KQMRI+H   F+   +++
Sbjct: 18  EKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQ 77

Query: 84  FRPTIYSNVIKGMRVLVDAREKL--HIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRV 141
               I  NV   +  +V A   +   +P  +  NQ   D + S    AP+      +   
Sbjct: 78  KILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI---APIT-----DFEY 129

Query: 142 FLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARR 201
             ++   ++ LW D G++  ++R  E+QL +  +YFL+ +D +   DY P+ QD+L  R 
Sbjct: 130 SQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRV 189

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
            T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+++ + S ++ V+ ED  
Sbjct: 190 LTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNN 249

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFEG----- 314
           TNRL ESL++FE+I NNR    +SIILFLNK D+L EKV      I+DYF E+       
Sbjct: 250 TNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPE 309

Query: 315 --------DPHCLRDVQKFLVECFR--NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKD 364
                   DP   R  + F+ + F   +      +   Y HFT A++TENIR VF D +D
Sbjct: 310 DATPDAGEDPKVTR-AKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRD 368

Query: 365 TILHDNLKQLML 376
            I   +LKQ  L
Sbjct: 369 IIQRMHLKQYEL 380


>gi|4504047 GNAS complex locus GNASL [Homo sapiens]
          Length = 394

 Score =  229 bits (583), Expect = 4e-60
 Identities = 142/384 (36%), Positives = 209/384 (54%), Gaps = 37/384 (9%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E  Q+  +K+I+K L ++K   +   ++LLLGAGESGKST +KQMRI+H   F+    EE
Sbjct: 16  EKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEE 75

Query: 84  FRPT---------------IYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTR 128
                              I +N+ + +  +V A   L +P  + +N ++      F   
Sbjct: 76  DPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRVD 129

Query: 129 APMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPD 188
             ++   + +     ++    +ALW D G++  Y+R  E+QL +  +YFLD +D + + D
Sbjct: 130 YILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQAD 189

Query: 189 YIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVS 248
           Y+PS QD+L  R  T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+F+V+
Sbjct: 190 YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA 249

Query: 249 SSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIK 306
           SS ++ V+ ED  TNRL E+LN+F++I NNR    +S+ILFLNK DLL EKV      I+
Sbjct: 250 SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIE 309

Query: 307 DYFLEFE-------------GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAINT 352
           DYF EF               DP   R       E  R +      +   Y HFT A++T
Sbjct: 310 DYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDT 369

Query: 353 ENIRLVFRDVKDTILHDNLKQLML 376
           ENIR VF D +D I   +L+Q  L
Sbjct: 370 ENIRRVFNDCRDIIQRMHLRQYEL 393


>gi|117938762 GNAS complex locus isoform f [Homo sapiens]
          Length = 395

 Score =  228 bits (582), Expect = 5e-60
 Identities = 142/385 (36%), Positives = 209/385 (54%), Gaps = 38/385 (9%)

Query: 24  EAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREE 83
           E  Q+  +K+I+K L ++K   +   ++LLLGAGESGKST +KQMRI+H   F+    EE
Sbjct: 16  EKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEE 75

Query: 84  FRPT----------------IYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDT 127
                               I +N+ + +  +V A   L +P  + +N ++      F  
Sbjct: 76  DPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRV 129

Query: 128 RAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEP 187
              ++   + +     ++    +ALW D G++  Y+R  E+QL +  +YFLD +D + + 
Sbjct: 130 DYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQA 189

Query: 188 DYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLV 247
           DY+PS QD+L  R  T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+F+V
Sbjct: 190 DYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVV 249

Query: 248 SSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSI 305
           +SS ++ V+ ED  TNRL E+LN+F++I NNR    +S+ILFLNK DLL EKV      I
Sbjct: 250 ASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI 309

Query: 306 KDYFLEFE-------------GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAIN 351
           +DYF EF               DP   R       E  R +      +   Y HFT A++
Sbjct: 310 EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVD 369

Query: 352 TENIRLVFRDVKDTILHDNLKQLML 376
           TENIR VF D +D I   +L+Q  L
Sbjct: 370 TENIRRVFNDCRDIIQRMHLRQYEL 394


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score =  226 bits (577), Expect = 2e-59
 Identities = 143/381 (37%), Positives = 207/381 (54%), Gaps = 37/381 (9%)

Query: 27   QQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRP 86
            ++++SK IDK L  EK       ++LLLGAGESGKST +KQMRI+H   F+    EE   
Sbjct: 662  EKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQ 721

Query: 87   T---------------IYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPM 131
                            I +N+ + +  +V A   L +P  + +N ++      F     +
Sbjct: 722  AARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNL-VPPVELANPEN-----QFRVDYIL 775

Query: 132  AAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIP 191
            +   + +     ++    +ALW D G++  Y+R  E+QL +  +YFLD +D + + DY+P
Sbjct: 776  SVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVP 835

Query: 192  SQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSE 251
            S QD+L  R  T GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+F+V+SS 
Sbjct: 836  SDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSS 895

Query: 252  FDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYF 309
            ++ V+ ED  TNRL E+LN+F++I NNR    +S+ILFLNK DLL EKV      I+DYF
Sbjct: 896  YNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYF 955

Query: 310  LEFE-------------GDPHCLRDVQKFLVECFR-NKRRDQQQKPLYHHFTTAINTENI 355
             EF               DP   R       E  R +      +   Y HFT A++TENI
Sbjct: 956  PEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENI 1015

Query: 356  RLVFRDVKDTILHDNLKQLML 376
            R VF D +D I   +L+Q  L
Sbjct: 1016 RRVFNDCRDIIQRMHLRQYEL 1036


>gi|33695153 guanine nucleotide binding protein (G protein), alpha
           activating activity polypeptide, olfactory type isoform
           1 [Homo sapiens]
          Length = 458

 Score =  225 bits (573), Expect = 6e-59
 Identities = 137/370 (37%), Positives = 207/370 (55%), Gaps = 28/370 (7%)

Query: 26  EQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFR 85
           E ++ S+ ID+ L  +K  +++  ++LLLGAGESGKST +KQMRI+H   F+   +++  
Sbjct: 97  EARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKI 156

Query: 86  PTIYSNVIKGMRVLVDAREKL--HIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFL 143
             I  NV   +  +V A   +   +P  +  NQ   D + S    AP+      +     
Sbjct: 157 LDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSI---APIT-----DFEYSQ 208

Query: 144 QYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPT 203
           ++   ++ LW D G++  ++R  E+QL +  +YFL+ +D +   DY P+ QD+L  R  T
Sbjct: 209 EFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLT 268

Query: 204 KGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTN 263
            GI E  F++  V F M DVGGQR ER++W +CF+ VT+I+++ + S ++ V+ ED  TN
Sbjct: 269 SGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTN 328

Query: 264 RLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQI--VSIKDYFLEFEG------- 314
           RL ESL++FE+I NNR    +SIILFLNK D+L EKV      I+DYF E+         
Sbjct: 329 RLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDA 388

Query: 315 ------DPHCLRDVQKFLVECFR--NKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTI 366
                 DP   R  + F+ + F   +      +   Y HFT A++TENIR VF D +D I
Sbjct: 389 TPDAGEDPKVTR-AKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDII 447

Query: 367 LHDNLKQLML 376
              +LKQ  L
Sbjct: 448 QRMHLKQYEL 457


>gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]
          Length = 175

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 18/114 (15%)

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
           PT G +      KNV F + DVGGQ   R  W   +     ++F+V  ++ D        
Sbjct: 43  PTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD-------- 94

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL--------LEEKVQIVSIKD 307
             R+ E+      I+N+R   +  I++F NK DL        ++EK+ +  I+D
Sbjct: 95  --RIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRD 146


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 15/118 (12%)

Query: 193 QQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEF 252
           +QD  +   PT G +    E KN+ F + DVGG+   R  W   + +  +++F+V SS  
Sbjct: 425 KQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHR 484

Query: 253 DQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL-----LEEKVQIVSI 305
           D          R++E+ +    ++  +   +  +++F NK D+     +EE  +++S+
Sbjct: 485 D----------RISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSL 532


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 15/118 (12%)

Query: 193 QQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEF 252
           +QD  +   PT G +    E KN+ F + DVGG+   R  W   + +  +++F+V SS  
Sbjct: 425 KQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHR 484

Query: 253 DQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL-----LEEKVQIVSI 305
           D          R++E+ +    ++  +   +  +++F NK D+     +EE  +++S+
Sbjct: 485 D----------RISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSL 532


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 15/118 (12%)

Query: 193 QQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEF 252
           +QD  +   PT G +    E KN+ F + DVGG+   R  W   + +  +++F+V SS  
Sbjct: 425 KQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHR 484

Query: 253 DQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL-----LEEKVQIVSI 305
           D          R++E+ +    ++  +   +  +++F NK D+     +EE  +++S+
Sbjct: 485 D----------RISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSL 532


>gi|4502209 ADP-ribosylation factor 5 [Homo sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 10/94 (10%)

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
           PT G +    E KN+ F + DVGGQ   R  W   F +   ++F+V S++          
Sbjct: 47  PTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND---------- 96

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL 295
             R+ ES +  + ++      +  +++F NK D+
Sbjct: 97  RERVQESADELQKMLQEDELRDAVLLVFANKQDM 130


>gi|4502205 ADP-ribosylation factor 4 [Homo sapiens]
          Length = 180

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 10/94 (10%)

Query: 202 PTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRL 261
           PT G +    E KN+ F + DVGGQ   R  W   F +   ++F+V S++ +++     +
Sbjct: 47  PTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERI---QEV 103

Query: 262 TNRLTESLNIFETIVNNRVFSNVSIILFLNKTDL 295
            + L + L + E         +  ++LF NK DL
Sbjct: 104 ADELQKMLLVDE-------LRDAVLLLFANKQDL 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,779,192
Number of Sequences: 37866
Number of extensions: 531465
Number of successful extensions: 1448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1341
Number of HSP's gapped (non-prelim): 73
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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