Guide to the Human Genome
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Search of human proteins with 239787762

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]           758   0.0  
gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]           758   0.0  
gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens]           758   0.0  
gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens]           758   0.0  
gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens]           750   0.0  
gi|157820785 SH2 domain containing 7 [Homo sapiens]                   115   8e-26
gi|14249584 hematopoietic SH2 domain containing [Homo sapiens]         96   6e-20
gi|21361891 SH2 domain containing 4A [Homo sapiens]                    60   3e-09
gi|222537752 Src homology 2 domain containing transforming prote...    55   1e-07
gi|117320537 phospholipase C, gamma 2 [Homo sapiens]                   52   1e-06
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]          50   4e-06
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]          50   4e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   49   5e-06
gi|58219064 Src homology 2 domain containing E [Homo sapiens]          49   9e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   48   1e-05
gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens]      47   2e-05
gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens]      47   2e-05
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...    45   1e-04
gi|111074524 Src homology 2 domain containing F [Homo sapiens]         45   1e-04
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho...    45   1e-04
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho...    45   1e-04
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho...    45   1e-04
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   44   2e-04
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   44   2e-04
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]               44   3e-04
gi|19923345 RNA binding motif protein 12 [Homo sapiens]                44   3e-04
gi|23510462 RNA binding motif protein 12 [Homo sapiens]                44   3e-04
gi|242247193 SH2B adaptor protein 2 [Homo sapiens]                     42   7e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    42   7e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    42   7e-04

>gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]
          Length = 361

 Score =  758 bits (1958), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
           MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60

Query: 61  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120
           HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD
Sbjct: 61  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120

Query: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180
           GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK
Sbjct: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR
Sbjct: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300
           PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR
Sbjct: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300

Query: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360
           PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP
Sbjct: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360

Query: 361 Q 361
           Q
Sbjct: 361 Q 361


>gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]
          Length = 371

 Score =  758 bits (1958), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
           MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 11  MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 70

Query: 61  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120
           HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD
Sbjct: 71  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 130

Query: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180
           GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK
Sbjct: 131 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 190

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR
Sbjct: 191 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 250

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300
           PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR
Sbjct: 251 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 310

Query: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360
           PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP
Sbjct: 311 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 370

Query: 361 Q 361
           Q
Sbjct: 371 Q 371


>gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens]
          Length = 389

 Score =  758 bits (1958), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
           MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 29  MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 88

Query: 61  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120
           HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD
Sbjct: 89  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 148

Query: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180
           GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK
Sbjct: 149 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 208

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR
Sbjct: 209 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 268

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300
           PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR
Sbjct: 269 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 328

Query: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360
           PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP
Sbjct: 329 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 388

Query: 361 Q 361
           Q
Sbjct: 389 Q 389


>gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens]
          Length = 389

 Score =  758 bits (1958), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
           MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 29  MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 88

Query: 61  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120
           HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD
Sbjct: 89  HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 148

Query: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180
           GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK
Sbjct: 149 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 208

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR
Sbjct: 209 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 268

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300
           PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR
Sbjct: 269 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 328

Query: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360
           PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP
Sbjct: 329 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 388

Query: 361 Q 361
           Q
Sbjct: 389 Q 389


>gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens]
          Length = 399

 Score =  750 bits (1937), Expect = 0.0
 Identities = 361/371 (97%), Positives = 361/371 (97%), Gaps = 10/371 (2%)

Query: 1   MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
           MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 29  MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 88

Query: 61  HGAAPAWFHGFITRR----------EAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC 110
           HGAAPAWFHGFITRR          EAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC
Sbjct: 89  HGAAPAWFHGFITRRVRPPLSVTHREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC 148

Query: 111 RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL 170
           RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL
Sbjct: 149 RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL 208

Query: 171 RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 230
           RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE
Sbjct: 209 RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 268

Query: 231 VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG 290
           VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG
Sbjct: 269 VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG 328

Query: 291 HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR 350
           HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR
Sbjct: 329 HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR 388

Query: 351 GQAWLPLGPPQ 361
           GQAWLPLGPPQ
Sbjct: 389 GQAWLPLGPPQ 399


>gi|157820785 SH2 domain containing 7 [Homo sapiens]
          Length = 451

 Score =  115 bits (287), Expect = 8e-26
 Identities = 52/119 (43%), Positives = 77/119 (64%)

Query: 42  LQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFV 101
           LQ     WF +TQA ++LQ+GA P WFHGFITR++ E+LL  K  G +L+R S+ A  ++
Sbjct: 26  LQELALKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYI 85

Query: 102 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLAR 160
           L+YR    CRHF++ QLR+ R+++ G+  +H+ L +L+ HY    L P+ E LT    R
Sbjct: 86  LSYRGSDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPR 144


>gi|14249584 hematopoietic SH2 domain containing [Homo sapiens]
          Length = 352

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)

Query: 49  WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 108
           WF  TQ   L Q G  P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 17  WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75

Query: 109 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 163
            C HF++  L DG  ++ GE  AH  L  L+  +   P+ P  E LT+P  ++ P
Sbjct: 76  SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130


>gi|21361891 SH2 domain containing 4A [Homo sapiens]
          Length = 454

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 9/130 (6%)

Query: 43  QAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREA-ERLLEPKPQGCYLVRFSESAVTFV 101
           Q   RA +QKT             WFHG +T ++A E LL     G +L+R SE    + 
Sbjct: 330 QLPLRAGYQKTS-------DTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA 382

Query: 102 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYG-ETLTEPLAR 160
           L+Y S   C+HFL+    D    +  +   HA L DL+ ++   P++  G E L  P  +
Sbjct: 383 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ 442

Query: 161 QTPEPAGLSL 170
           Q   P  L L
Sbjct: 443 QDQLPDYLEL 452


>gi|222537752 Src homology 2 domain containing transforming protein
           D [Homo sapiens]
          Length = 340

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 6/102 (5%)

Query: 67  WFHGFITRREAERLLEPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 125
           WFHG + R +AE LL    +G YLVR SE +     L+ RS     H   A+ R+ + VV
Sbjct: 240 WFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQ-VV 298

Query: 126 LGEDSA-HARLQDLLLHYTAHPLSPYGE---TLTEPLARQTP 163
           LG+ S     + +L+LHY++ PL   G     L  P+  QTP
Sbjct: 299 LGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP 340


>gi|117320537 phospholipase C, gamma 2 [Homo sapiens]
          Length = 1265

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 4/88 (4%)

Query: 61  HGAAPAWFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLR 119
           H + P W++  ++R EAE +L   P+ G +L+R  E + ++ +T+R+R   +H  +   R
Sbjct: 641 HESKP-WYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRIN--R 697

Query: 120 DGRHVVLGEDSAHARLQDLLLHYTAHPL 147
           DGRH VLG  +    L +L+ +Y  H L
Sbjct: 698 DGRHFVLGTSAYFESLVELVSYYEKHSL 725


>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
          Length = 1291

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%)

Query: 67  WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 125
           W+H  +TR +AE +L   P+ G +LVR      ++ +++R+    +H  + Q  +G+ V+
Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725

Query: 126 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 184
           LG +S    L DL+ +Y  HPL  Y +  L  P+  +  E  G    T E ++G+  +  
Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778

Query: 185 NPQY 188
           NP +
Sbjct: 779 NPGF 782


>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
          Length = 1290

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%)

Query: 67  WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 125
           W+H  +TR +AE +L   P+ G +LVR      ++ +++R+    +H  + Q  +G+ V+
Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725

Query: 126 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 184
           LG +S    L DL+ +Y  HPL  Y +  L  P+  +  E  G    T E ++G+  +  
Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778

Query: 185 NPQY 188
           NP +
Sbjct: 779 NPGF 782


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 58/200 (29%), Positives = 75/200 (37%), Gaps = 29/200 (14%)

Query: 143  TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 201
            T+   SP       P   + P P   SL    S   S++  P + Q SPI  Q   P+P 
Sbjct: 1035 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1090

Query: 202  QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 261
                  +K+P+Q L PK P P +P  PP   T P P  RP   P PS      P   +A 
Sbjct: 1091 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRP---PPPSGRSQPSPQAGLA- 1137

Query: 262  YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQ------NTGGSQLHS 315
               G G  G + +   +      + A   H   R S  R  P  Q      + G + L  
Sbjct: 1138 ---GPGPAGYSTARPTIPPRAGVISAPQSH--ARASAGRLTPESQSKTSETSKGSTFLPE 1192

Query: 316  ENSVIGQGPPLPHQPPPAWR 335
                    PP    PPPA R
Sbjct: 1193 PLKPQAAFPPQSSLPPPAQR 1212


>gi|58219064 Src homology 2 domain containing E [Homo sapiens]
          Length = 495

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 2/85 (2%)

Query: 67  WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 125
           W+HG I+R EAE  L+P  +  YLVR SES  + + +  ++   C H ++AQ +D ++  
Sbjct: 395 WYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKY-T 453

Query: 126 LGEDSAHARLQDLLLHYTAHPLSPY 150
           L + SA       ++HY ++   P+
Sbjct: 454 LNQTSAVFDSIPEVVHYYSNEKLPF 478


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 39/122 (31%), Positives = 51/122 (41%), Gaps = 19/122 (15%)

Query: 143  TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 201
            T+   SP       P   + P P   SL    S   S++  P + Q SPI  Q   P+P 
Sbjct: 1040 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1095

Query: 202  QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAP-----RPKPSNPIYNEPD 256
                  +K+P+Q L PK P P +P  PP   T P P  RP P      P P+   +  P 
Sbjct: 1096 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRPPPPSGARSPAPTRKEFGAPK 1146

Query: 257  EP 258
             P
Sbjct: 1147 SP 1148


>gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens]
          Length = 532

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%)

Query: 15  SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 66
           SP    A+ NT       G+A R  E P E       E +AW +KT     L   A+   
Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420

Query: 67  ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 113
                     WFHG I+R E++RL+  +    G +LVR S+ +   FVL+       +H+
Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480

Query: 114 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 148
           L+    +   +    D    R  DLL     H L+
Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515


>gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens]
          Length = 532

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%)

Query: 15  SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 66
           SP    A+ NT       G+A R  E P E       E +AW +KT     L   A+   
Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420

Query: 67  ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 113
                     WFHG I+R E++RL+  +    G +LVR S+ +   FVL+       +H+
Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480

Query: 114 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 148
           L+    +   +    D    R  DLL     H L+
Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515


>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
           [Homo sapiens]
          Length = 303

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 67/267 (25%), Positives = 106/267 (39%), Gaps = 60/267 (22%)

Query: 66  AWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRHV 124
           AW+ G ++R+EA+  L+ +  G +LVR S +    +VL+    +   H+++  L + R  
Sbjct: 13  AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72

Query: 125 VLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGL----SLRTEESNF--- 177
           +  ++  H  L  LL  Y  H L     TL EP  R    P G     +L T E N    
Sbjct: 73  IGDQEFDH--LPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYV 128

Query: 178 -------GSKSQDPNPQYSPIIKQGQAPVPMQKE-----GAGEKEPSQLLRPKPPIPAKP 225
                  G+ ++D         K+G+  V ++K       A  K+    + P P +    
Sbjct: 129 RTLYDFPGNDAEDLP------FKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLV 182

Query: 226 QLPP---------EVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 276
           +  P           Y IP P H  A +P+ + P+               GSPG A +  
Sbjct: 183 RSSPHGKHGNRNSNSYGIPEPAHAYA-QPQTTTPL-----------PAVSGSPGAAIT-- 228

Query: 277 YVEVEDEGLPATLGHPVLRKSWSRPVP 303
                   LP+T   PV  K+  + VP
Sbjct: 229 -------PLPSTQNGPVFAKAIQKRVP 248


>gi|111074524 Src homology 2 domain containing F [Homo sapiens]
          Length = 423

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 4/100 (4%)

Query: 67  WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 125
           W+HG I+R +AE LL    +  YLVR SE++   F L+ +S     H  L++ ++ ++V+
Sbjct: 323 WYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVL 382

Query: 126 LGEDSAHARLQDLLLHYTAHPLSPYGE---TLTEPLARQT 162
                  + + +++ HY +  L   G    +L  P+A +T
Sbjct: 383 GQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 422


>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
            sapiens]
          Length = 1645

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)

Query: 156  EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 209
            + +A    +    S+RT +S+  S+S   +PQ  P  +          P  + G+  K  
Sbjct: 1399 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1458

Query: 210  EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 258
             P Q  +P    + P+   PQ PP  Y+   P H        P   P PS PI+     P
Sbjct: 1459 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1511

Query: 259  IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 311
            +        +PG APSNI       +  +    P  + +      W R V P      G+
Sbjct: 1512 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1566

Query: 312  QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 345
              +SE    G  PP+P  H P       P +W + L  N   Q
Sbjct: 1567 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1609


>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
            sapiens]
          Length = 1644

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)

Query: 156  EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 209
            + +A    +    S+RT +S+  S+S   +PQ  P  +          P  + G+  K  
Sbjct: 1398 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1457

Query: 210  EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 258
             P Q  +P    + P+   PQ PP  Y+   P H        P   P PS PI+     P
Sbjct: 1458 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1510

Query: 259  IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 311
            +        +PG APSNI       +  +    P  + +      W R V P      G+
Sbjct: 1511 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1565

Query: 312  QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 345
              +SE    G  PP+P  H P       P +W + L  N   Q
Sbjct: 1566 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1608


>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
            sapiens]
          Length = 1640

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)

Query: 156  EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 209
            + +A    +    S+RT +S+  S+S   +PQ  P  +          P  + G+  K  
Sbjct: 1394 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1453

Query: 210  EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 258
             P Q  +P    + P+   PQ PP  Y+   P H        P   P PS PI+     P
Sbjct: 1454 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1506

Query: 259  IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 311
            +        +PG APSNI       +  +    P  + +      W R V P      G+
Sbjct: 1507 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1561

Query: 312  QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 345
              +SE    G  PP+P  H P       P +W + L  N   Q
Sbjct: 1562 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1604


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%)

Query: 143  TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 201
            T+   SP       P   + P P   SL    S   S++  P + Q SPI  Q   P+P 
Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134

Query: 202  QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 261
            QK+ A   EP +   P+P  P     PP+    P     PAP  K    I   P   +A 
Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194

Query: 262  YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 321
              M      EAP +     +D         P  +   + P P G +T    +     VI 
Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244

Query: 322  QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 356
               P  H    A R T P + S+     +G  +LP
Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%)

Query: 143  TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 201
            T+   SP       P   + P P   SL    S   S++  P + Q SPI  Q   P+P 
Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134

Query: 202  QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 261
            QK+ A   EP +   P+P  P     PP+    P     PAP  K    I   P   +A 
Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194

Query: 262  YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 321
              M      EAP +     +D         P  +   + P P G +T    +     VI 
Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244

Query: 322  QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 356
               P  H    A R T P + S+     +G  +LP
Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277


>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
          Length = 330

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 12/171 (7%)

Query: 65  PAWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRH 123
           P WFH  ++R +AE LL  K  G +++R S+S+   F ++ R     +HF + +   G +
Sbjct: 56  PKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 124 VVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESN----FGS 179
            +  E      L  L+ +Y  + +S   +       R+     G SL           G+
Sbjct: 116 FLWTE--KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGA 173

Query: 180 KSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 230
             ++  P  +  +      +P+Q+     + P        P P + Q PP+
Sbjct: 174 VGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQY-----APAPQQLQQPPQ 219


>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%)

Query: 217 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 276
           P PPIPA P LPP     P+P   P P   P  P+   P  P          P   P   
Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237

Query: 277 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 330
                   LP   G P L      P+P G N  G+ ++  N++  +  GP  P  P
Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%)

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           S  P P   PI      PVP          P   L P PP+P  P +P       VP   
Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 276
           P P      P+   P  P+     G G+P    +N+
Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272


>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%)

Query: 217 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 276
           P PPIPA P LPP     P+P   P P   P  P+   P  P          P   P   
Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237

Query: 277 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 330
                   LP   G P L      P+P G N  G+ ++  N++  +  GP  P  P
Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%)

Query: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
           S  P P   PI      PVP          P   L P PP+P  P +P       VP   
Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236

Query: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 276
           P P      P+   P  P+     G G+P    +N+
Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272


>gi|242247193 SH2B adaptor protein 2 [Homo sapiens]
          Length = 675

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 25/190 (13%)

Query: 67  WFHGFITRREAERLL---EPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGR 122
           WFHG ++R +A +L+    P+  G +++R SE+    +VLT+  +   +H  L+    G+
Sbjct: 460 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 519

Query: 123 -HVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKS 181
            HV   +      + D+L H+  HP+         PL  ++   A ++LR+       ++
Sbjct: 520 CHV---QHLWFQSVLDMLRHFHTHPI---------PL--ESGGSADITLRSY-----VRA 560

Query: 182 QDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRP 241
           QDP P+  P      A      +  G+   S L     P PA P       +        
Sbjct: 561 QDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACP-PASPSDAAGASSSSASSSSA 619

Query: 242 APRPKPSNPI 251
           A  P P  P+
Sbjct: 620 ASGPAPPRPV 629


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%)

Query: 178 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 234
           G +S    P +SP    G+ PVP     +G  EP  +++  P+P + +KP  +PP V + 
Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190

Query: 235 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 294
           P P  + +P  + S P+   P +P         SPG  P                     
Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220

Query: 295 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 333
                 P PG + T  GG  +     S +S     PPLP  P  A
Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%)

Query: 184 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 234
           P P  +   K    P P+    +  +E   P      KPP+P+ P      Q PP     
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309

Query: 235 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 289
           P P  RP P P P +   N+     P   ++  +     P    S        E  P  +
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369

Query: 290 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 333
             P  R     P P     G +        QL S + V     G  PPLP   P A
Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%)

Query: 178 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 234
           G +S    P +SP    G+ PVP     +G  EP  +++  P+P + +KP  +PP V + 
Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190

Query: 235 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 294
           P P  + +P  + S P+   P +P         SPG  P                     
Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220

Query: 295 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 333
                 P PG + T  GG  +     S +S     PPLP  P  A
Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259



 Score = 32.0 bits (71), Expect = 0.88
 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%)

Query: 184 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 234
           P P  +   K    P P+    +  +E   P      KPP+P+ P      Q PP     
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309

Query: 235 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 289
           P P  RP P P P +   N+     P   ++  +     P    S        E  P  +
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369

Query: 290 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 333
             P  R     P P     G +        QL S + V     G  PPLP   P A
Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,799,915
Number of Sequences: 37866
Number of extensions: 1327989
Number of successful extensions: 7882
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 729
Number of HSP's that attempted gapping in prelim test: 5293
Number of HSP's gapped (non-prelim): 2369
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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