Guide to the Human Genome
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Name: SH2D4A Sequence: fasta or formatted (454aa) NCBI GI: 21361891
Description:

SH2 domain containing 4A

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.8         31           2
 C cysteine            0.9          4           1
 D aspartate           4.8         22           1
 E glutamate          11.5         52           3
 F phenylalanine       2.4         11           2
 G glycine             4.2         19           2
 H histidine           2.2         10           2
 I isoleucine          4.6         21           2
 K lysine             10.4         47           3
 L leucine            10.8         49           3
 M methionine          2.0          9           1
 N asparagine          2.2         10           1
 P proline             5.5         25           2
 Q glutamine           7.0         32           2
 R arginine            6.4         29           2
 S serine              7.7         35           4
 T threonine           2.9         13           1
 V valine              2.9         13           2
 W tryptophan          2.0          9           1
 Y tyrosine            2.9         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH2 domain containing 4A 
SH2D4B                0.221   SH2 domain containing 4B isoform 1 
SH2D4B                0.146   SH2 domain containing 4B isoform 2 
SH2D7                 0.069   SH2 domain containing 7 
HSH2D                 0.061   hematopoietic SH2 domain containing 
SH2D2A                0.039   SH2 domain protein 2A isoform 4 
SH2D2A                0.039   SH2 domain protein 2A isoform 3 
SH2D2A                0.039   SH2 domain protein 2A isoform 2 
SH2D2A                0.039   SH2 domain protein 2A isoform 2 
LOC283685             0.036   PREDICTED: golgi autoantigen, golgin subfamily a-li...
LOC727832             0.034   golgi autoantigen, golgin subfamily a-like 
SH2D2A                0.034   SH2 domain protein 2A isoform 1 
DAPP1                 0.033   dual adaptor of phosphotyrosine and 3-phosphoinosit...
LOC283767             0.032   golgi autoantigen, golgin subfamily a-like 
TCHH                  0.032   trichohyalin 
LOC440243             0.032   PREDICTED: Putative golgin subfamily A member 6-lik...
MYH14                 0.030   myosin, heavy chain 14 isoform 1 
MYH14                 0.030   myosin, heavy chain 14 isoform 2 
MYH14                 0.030   myosin, heavy chain 14 isoform 3 
RASA1                 0.030   RAS p21 protein activator 1 isoform 1 
PTPN11                0.028   protein tyrosine phosphatase, non-receptor type 11 [...
LOC645202             0.028   PREDICTED: hypothetical protein LOC645202 
STK10                 0.028   serine/threonine kinase 10 
AKAP13                0.028   A-kinase anchor protein 13 isoform 1 
AKAP13                0.028   A-kinase anchor protein 13 isoform 3 
AKAP13                0.028   A-kinase anchor protein 13 isoform 2 
GRB2                  0.027   growth factor receptor-bound protein 2 isoform 1 [Hom...
PLCG1                 0.027   phospholipase C, gamma 1 isoform a 
PLCG1                 0.027   phospholipase C, gamma 1 isoform b 
RASA1                 0.027   RAS p21 protein activator 1 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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