Guide to the Human Genome
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Name: SHF Sequence: fasta or formatted (423aa) NCBI GI: 111074524
Description:

Src homology 2 domain containing F

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         28           1
 C cysteine            0.9          4           1
 D aspartate           4.7         20           2
 E glutamate           9.5         40           2
 F phenylalanine       1.4          6           1
 G glycine             6.9         29           2
 H histidine           2.4         10           2
 I isoleucine          3.1         13           2
 K lysine              6.1         26           3
 L leucine             8.5         36           2
 M methionine          2.1          9           2
 N asparagine          2.4         10           1
 P proline            12.5         53           3
 Q glutamine           3.5         15           2
 R arginine            6.6         28           1
 S serine             11.6         49           3
 T threonine           3.5         15           2
 V valine              3.1         13           1
 W tryptophan          1.9          8           1
 Y tyrosine            2.6         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Src homology 2 domain containing F 
SHB                   0.289   Src homology 2 domain containing adaptor protein B ...
SHE                   0.262   Src homology 2 domain containing E 
SHD                   0.259   Src homology 2 domain containing transforming prote...
NCK1                  0.051   NCK adaptor protein 1 
ABL2                  0.043   arg tyrosine kinase isoform c 
ABL2                  0.043   arg tyrosine kinase isoform b 
ABL2                  0.043   arg tyrosine kinase isoform e 
ABL2                  0.043   arg tyrosine kinase isoform d 
ABL2                  0.043   arg tyrosine kinase isoform a 
NCK2                  0.040   NCK adaptor protein 2 isoform A 
NCK2                  0.040   NCK adaptor protein 2 isoform A 
ABL1                  0.039   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.039   c-abl oncogene 1, receptor tyrosine kinase isoform b...
TENC1                 0.039   tensin like C1 domain containing phosphatase isoform...
TENC1                 0.039   tensin like C1 domain containing phosphatase isoform...
TENC1                 0.039   tensin like C1 domain containing phosphatase isoform...
RASA1                 0.038   RAS p21 protein activator 1 isoform 1 
RASA1                 0.038   RAS p21 protein activator 1 isoform 2 
SH2D7                 0.034   SH2 domain containing 7 
FRK                   0.033   fyn-related kinase 
FER                   0.032   fer (fps/fes related) tyrosine kinase 
PIK3R1                0.032   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
SHC4                  0.032   rai-like protein 
PIK3R3                0.032   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.032   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PLCG2                 0.031   phospholipase C, gamma 2 
PIK3R1                0.031   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
GRAP2                 0.029   GRB2-related adaptor protein 2 
PIK3R1                0.029   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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