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Search of human proteins with 239787758
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]
(371 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens] 778 0.0
gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] 772 0.0
gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens] 772 0.0
gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens] 764 0.0
gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens] 758 0.0
gi|157820785 SH2 domain containing 7 [Homo sapiens] 115 8e-26
gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] 96 7e-20
gi|21361891 SH2 domain containing 4A [Homo sapiens] 60 3e-09
gi|222537752 Src homology 2 domain containing transforming prote... 55 1e-07
gi|117320537 phospholipase C, gamma 2 [Homo sapiens] 52 1e-06
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] 50 4e-06
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] 50 4e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 49 6e-06
gi|58219064 Src homology 2 domain containing E [Homo sapiens] 49 9e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 48 1e-05
gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] 47 2e-05
gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] 47 2e-05
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 45 1e-04
gi|111074524 Src homology 2 domain containing F [Homo sapiens] 45 1e-04
gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho... 45 1e-04
gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho... 45 1e-04
gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho... 45 1e-04
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 44 2e-04
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 44 2e-04
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 44 3e-04
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 44 3e-04
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 44 3e-04
gi|242247193 SH2B adaptor protein 2 [Homo sapiens] 42 7e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 42 7e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 42 7e-04
>gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]
Length = 371
Score = 778 bits (2009), Expect = 0.0
Identities = 371/371 (100%), Positives = 371/371 (100%)
Query: 1 MSPSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWF 60
MSPSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWF
Sbjct: 1 MSPSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWF 60
Query: 61 QKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC 120
QKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC
Sbjct: 61 QKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCC 120
Query: 121 RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL 180
RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL
Sbjct: 121 RHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSL 180
Query: 181 RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 240
RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE
Sbjct: 181 RTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 240
Query: 241 VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG 300
VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG
Sbjct: 241 VYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLG 300
Query: 301 HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR 360
HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR
Sbjct: 301 HPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDR 360
Query: 361 GQAWLPLGPPQ 371
GQAWLPLGPPQ
Sbjct: 361 GQAWLPLGPPQ 371
>gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 772 bits (1993), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 4 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 63
STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT
Sbjct: 22 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 81
Query: 64 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 123
QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF
Sbjct: 82 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 141
Query: 124 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 183
LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE
Sbjct: 142 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 201
Query: 184 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 243
ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT
Sbjct: 202 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 261
Query: 244 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 303
IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV
Sbjct: 262 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 321
Query: 304 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 363
LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA
Sbjct: 322 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 381
Query: 364 WLPLGPPQ 371
WLPLGPPQ
Sbjct: 382 WLPLGPPQ 389
>gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 772 bits (1993), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 4 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 63
STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT
Sbjct: 22 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 81
Query: 64 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 123
QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF
Sbjct: 82 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 141
Query: 124 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 183
LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE
Sbjct: 142 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 201
Query: 184 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 243
ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT
Sbjct: 202 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 261
Query: 244 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 303
IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV
Sbjct: 262 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 321
Query: 304 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 363
LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA
Sbjct: 322 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 381
Query: 364 WLPLGPPQ 371
WLPLGPPQ
Sbjct: 382 WLPLGPPQ 389
>gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens]
Length = 399
Score = 764 bits (1972), Expect = 0.0
Identities = 368/378 (97%), Positives = 368/378 (97%), Gaps = 10/378 (2%)
Query: 4 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 63
STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT
Sbjct: 22 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 81
Query: 64 QAHWLLQHGAAPAWFHGFITRR----------EAERLLEPKPQGCYLVRFSESAVTFVLT 113
QAHWLLQHGAAPAWFHGFITRR EAERLLEPKPQGCYLVRFSESAVTFVLT
Sbjct: 82 QAHWLLQHGAAPAWFHGFITRRVRPPLSVTHREAERLLEPKPQGCYLVRFSESAVTFVLT 141
Query: 114 YRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 173
YRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP
Sbjct: 142 YRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 201
Query: 174 EPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPA 233
EPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPA
Sbjct: 202 EPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPA 261
Query: 234 KPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDE 293
KPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDE
Sbjct: 262 KPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDE 321
Query: 294 GLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLS 353
GLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLS
Sbjct: 322 GLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLS 381
Query: 354 RQVLQDRGQAWLPLGPPQ 371
RQVLQDRGQAWLPLGPPQ
Sbjct: 382 RQVLQDRGQAWLPLGPPQ 399
>gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]
Length = 361
Score = 758 bits (1958), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 11 MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 70
MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ
Sbjct: 1 MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60
Query: 71 HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 130
HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD
Sbjct: 61 HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120
Query: 131 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 190
GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK
Sbjct: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180
Query: 191 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 250
SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR
Sbjct: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240
Query: 251 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 310
PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR
Sbjct: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300
Query: 311 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 370
PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP
Sbjct: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360
Query: 371 Q 371
Q
Sbjct: 361 Q 361
>gi|157820785 SH2 domain containing 7 [Homo sapiens]
Length = 451
Score = 115 bits (287), Expect = 8e-26
Identities = 52/119 (43%), Positives = 77/119 (64%)
Query: 52 LQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFV 111
LQ WF +TQA ++LQ+GA P WFHGFITR++ E+LL K G +L+R S+ A ++
Sbjct: 26 LQELALKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYI 85
Query: 112 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLAR 170
L+YR CRHF++ QLR+ R+++ G+ +H+ L +L+ HY L P+ E LT R
Sbjct: 86 LSYRGSDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPR 144
>gi|14249584 hematopoietic SH2 domain containing [Homo sapiens]
Length = 352
Score = 95.5 bits (236), Expect = 7e-20
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Query: 59 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 118
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75
Query: 119 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 173
C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P
Sbjct: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
>gi|21361891 SH2 domain containing 4A [Homo sapiens]
Length = 454
Score = 60.1 bits (144), Expect = 3e-09
Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 9/130 (6%)
Query: 53 QAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREA-ERLLEPKPQGCYLVRFSESAVTFV 111
Q RA +QKT WFHG +T ++A E LL G +L+R SE +
Sbjct: 330 QLPLRAGYQKTS-------DTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA 382
Query: 112 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYG-ETLTEPLAR 170
L+Y S C+HFL+ D + + HA L DL+ ++ P++ G E L P +
Sbjct: 383 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ 442
Query: 171 QTPEPAGLSL 180
Q P L L
Sbjct: 443 QDQLPDYLEL 452
>gi|222537752 Src homology 2 domain containing transforming protein
D [Homo sapiens]
Length = 340
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Query: 77 WFHGFITRREAERLLEPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 135
WFHG + R +AE LL +G YLVR SE + L+ RS H A+ R+ + VV
Sbjct: 240 WFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQ-VV 298
Query: 136 LGEDSA-HARLQDLLLHYTAHPLSPYGE---TLTEPLARQTP 173
LG+ S + +L+LHY++ PL G L P+ QTP
Sbjct: 299 LGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP 340
>gi|117320537 phospholipase C, gamma 2 [Homo sapiens]
Length = 1265
Score = 51.6 bits (122), Expect = 1e-06
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 4/88 (4%)
Query: 71 HGAAPAWFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLR 129
H + P W++ ++R EAE +L P+ G +L+R E + ++ +T+R+R +H + R
Sbjct: 641 HESKP-WYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRIN--R 697
Query: 130 DGRHVVLGEDSAHARLQDLLLHYTAHPL 157
DGRH VLG + L +L+ +Y H L
Sbjct: 698 DGRHFVLGTSAYFESLVELVSYYEKHSL 725
>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
Length = 1291
Score = 49.7 bits (117), Expect = 4e-06
Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
Query: 77 WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 135
W+H +TR +AE +L P+ G +LVR ++ +++R+ +H + Q +G+ V+
Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725
Query: 136 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 194
LG +S L DL+ +Y HPL Y + L P+ + E G T E ++G+ +
Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778
Query: 195 NPQY 198
NP +
Sbjct: 779 NPGF 782
>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
Length = 1290
Score = 49.7 bits (117), Expect = 4e-06
Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
Query: 77 WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 135
W+H +TR +AE +L P+ G +LVR ++ +++R+ +H + Q +G+ V+
Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725
Query: 136 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 194
LG +S L DL+ +Y HPL Y + L P+ + E G T E ++G+ +
Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778
Query: 195 NPQY 198
NP +
Sbjct: 779 NPGF 782
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 49.3 bits (116), Expect = 6e-06
Identities = 58/200 (29%), Positives = 75/200 (37%), Gaps = 29/200 (14%)
Query: 153 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 211
T+ SP P + P P SL S S++ P + Q SPI Q P+P
Sbjct: 1035 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1090
Query: 212 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 271
+K+P+Q L PK P P +P PP T P P RP P PS P +A
Sbjct: 1091 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRP---PPPSGRSQPSPQAGLA- 1137
Query: 272 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQ------NTGGSQLHS 325
G G G + + + + A H R S R P Q + G + L
Sbjct: 1138 ---GPGPAGYSTARPTIPPRAGVISAPQSH--ARASAGRLTPESQSKTSETSKGSTFLPE 1192
Query: 326 ENSVIGQGPPLPHQPPPAWR 345
PP PPPA R
Sbjct: 1193 PLKPQAAFPPQSSLPPPAQR 1212
>gi|58219064 Src homology 2 domain containing E [Homo sapiens]
Length = 495
Score = 48.5 bits (114), Expect = 9e-06
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Query: 77 WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 135
W+HG I+R EAE L+P + YLVR SES + + + ++ C H ++AQ +D ++
Sbjct: 395 WYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKY-T 453
Query: 136 LGEDSAHARLQDLLLHYTAHPLSPY 160
L + SA ++HY ++ P+
Sbjct: 454 LNQTSAVFDSIPEVVHYYSNEKLPF 478
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 48.1 bits (113), Expect = 1e-05
Identities = 39/122 (31%), Positives = 51/122 (41%), Gaps = 19/122 (15%)
Query: 153 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 211
T+ SP P + P P SL S S++ P + Q SPI Q P+P
Sbjct: 1040 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1095
Query: 212 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAP-----RPKPSNPIYNEPD 266
+K+P+Q L PK P P +P PP T P P RP P P P+ + P
Sbjct: 1096 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRPPPPSGARSPAPTRKEFGAPK 1146
Query: 267 EP 268
P
Sbjct: 1147 SP 1148
>gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%)
Query: 25 SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 76
SP A+ NT G+A R E P E E +AW +KT L A+
Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420
Query: 77 ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 123
WFHG I+R E++RL+ + G +LVR S+ + FVL+ +H+
Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480
Query: 124 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 158
L+ + + D R DLL H L+
Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515
>gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%)
Query: 25 SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 76
SP A+ NT G+A R E P E E +AW +KT L A+
Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420
Query: 77 ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 123
WFHG I+R E++RL+ + G +LVR S+ + FVL+ +H+
Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480
Query: 124 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 158
L+ + + D R DLL H L+
Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515
>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
[Homo sapiens]
Length = 303
Score = 45.1 bits (105), Expect = 1e-04
Identities = 67/267 (25%), Positives = 106/267 (39%), Gaps = 60/267 (22%)
Query: 76 AWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRHV 134
AW+ G ++R+EA+ L+ + G +LVR S + +VL+ + H+++ L + R
Sbjct: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 135 VLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGL----SLRTEESNF--- 187
+ ++ H L LL Y H L TL EP R P G +L T E N
Sbjct: 73 IGDQEFDH--LPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYV 128
Query: 188 -------GSKSQDPNPQYSPIIKQGQAPVPMQKE-----GAGEKEPSQLLRPKPPIPAKP 235
G+ ++D K+G+ V ++K A K+ + P P +
Sbjct: 129 RTLYDFPGNDAEDLP------FKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLV 182
Query: 236 QLPP---------EVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 286
+ P Y IP P H A +P+ + P+ GSPG A +
Sbjct: 183 RSSPHGKHGNRNSNSYGIPEPAHAYA-QPQTTTPL-----------PAVSGSPGAAIT-- 228
Query: 287 YVEVEDEGLPATLGHPVLRKSWSRPVP 313
LP+T PV K+ + VP
Sbjct: 229 -------PLPSTQNGPVFAKAIQKRVP 248
>gi|111074524 Src homology 2 domain containing F [Homo sapiens]
Length = 423
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
Query: 77 WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 135
W+HG I+R +AE LL + YLVR SE++ F L+ +S H L++ ++ ++V+
Sbjct: 323 WYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVL 382
Query: 136 LGEDSAHARLQDLLLHYTAHPLSPYGE---TLTEPLARQT 172
+ + +++ HY + L G +L P+A +T
Sbjct: 383 GQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 422
>gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo
sapiens]
Length = 1645
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)
Query: 166 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 219
+ +A + S+RT +S+ S+S +PQ P + P + G+ K
Sbjct: 1399 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1458
Query: 220 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 268
P Q +P + P+ PQ PP Y+ P H P P PS PI+ P
Sbjct: 1459 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1511
Query: 269 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 321
+ +PG APSNI + + P + + W R V P G+
Sbjct: 1512 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1566
Query: 322 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 355
+SE G PP+P H P P +W + L N Q
Sbjct: 1567 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1609
>gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo
sapiens]
Length = 1644
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)
Query: 166 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 219
+ +A + S+RT +S+ S+S +PQ P + P + G+ K
Sbjct: 1398 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1457
Query: 220 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 268
P Q +P + P+ PQ PP Y+ P H P P PS PI+ P
Sbjct: 1458 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1510
Query: 269 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 321
+ +PG APSNI + + P + + W R V P G+
Sbjct: 1511 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1565
Query: 322 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 355
+SE G PP+P H P P +W + L N Q
Sbjct: 1566 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1608
>gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo
sapiens]
Length = 1640
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%)
Query: 166 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 219
+ +A + S+RT +S+ S+S +PQ P + P + G+ K
Sbjct: 1394 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1453
Query: 220 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 268
P Q +P + P+ PQ PP Y+ P H P P PS PI+ P
Sbjct: 1454 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1506
Query: 269 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 321
+ +PG APSNI + + P + + W R V P G+
Sbjct: 1507 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1561
Query: 322 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 355
+SE G PP+P H P P +W + L N Q
Sbjct: 1562 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1604
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%)
Query: 153 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 211
T+ SP P + P P SL S S++ P + Q SPI Q P+P
Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134
Query: 212 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 271
QK+ A EP + P+P P PP+ P PAP K I P +A
Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
Query: 272 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 331
M EAP + +D P + + P P G +T + VI
Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244
Query: 332 QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 366
P H A R T P + S+ +G +LP
Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 44.3 bits (103), Expect = 2e-04
Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%)
Query: 153 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 211
T+ SP P + P P SL S S++ P + Q SPI Q P+P
Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134
Query: 212 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 271
QK+ A EP + P+P P PP+ P PAP K I P +A
Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
Query: 272 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 331
M EAP + +D P + + P P G +T + VI
Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244
Query: 332 QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 366
P H A R T P + S+ +G +LP
Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 43.5 bits (101), Expect = 3e-04
Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 12/171 (7%)
Query: 75 PAWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRH 133
P WFH ++R +AE LL K G +++R S+S+ F ++ R +HF + + G +
Sbjct: 56 PKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 134 VVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESN----FGS 189
+ E L L+ +Y + +S + R+ G SL G+
Sbjct: 116 FLWTE--KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGA 173
Query: 190 KSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 240
++ P + + +P+Q+ + P P P + Q PP+
Sbjct: 174 VGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQY-----APAPQQLQQPPQ 219
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 43.5 bits (101), Expect = 3e-04
Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%)
Query: 227 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 286
P PPIPA P LPP P+P P P P P+ P P P P
Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237
Query: 287 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 340
LP G P L P+P G N G+ ++ N++ + GP P P
Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285
Score = 30.4 bits (67), Expect = 2.7
Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%)
Query: 191 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 250
S P P PI PVP P L P PP+P P +P VP
Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236
Query: 251 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 286
P P P+ P P+ G G+P +N+
Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 43.5 bits (101), Expect = 3e-04
Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%)
Query: 227 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 286
P PPIPA P LPP P+P P P P P+ P P P P
Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237
Query: 287 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 340
LP G P L P+P G N G+ ++ N++ + GP P P
Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285
Score = 30.4 bits (67), Expect = 2.7
Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%)
Query: 191 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 250
S P P PI PVP P L P PP+P P +P VP
Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236
Query: 251 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 286
P P P+ P P+ G G+P +N+
Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272
>gi|242247193 SH2B adaptor protein 2 [Homo sapiens]
Length = 675
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 25/190 (13%)
Query: 77 WFHGFITRREAERLL---EPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGR 132
WFHG ++R +A +L+ P+ G +++R SE+ +VLT+ + +H L+ G+
Sbjct: 460 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 519
Query: 133 -HVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKS 191
HV + + D+L H+ HP+ PL ++ A ++LR+ ++
Sbjct: 520 CHV---QHLWFQSVLDMLRHFHTHPI---------PL--ESGGSADITLRSY-----VRA 560
Query: 192 QDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRP 251
QDP P+ P A + G+ S L P PA P +
Sbjct: 561 QDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACP-PASPSDAAGASSSSASSSSA 619
Query: 252 APRPKPSNPI 261
A P P P+
Sbjct: 620 ASGPAPPRPV 629
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%)
Query: 188 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 244
G +S P +SP G+ PVP +G EP +++ P+P + +KP +PP V +
Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 245 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 304
P P + +P + S P+ P +P SPG P
Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220
Query: 305 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 343
P PG + T GG + S +S PPLP P A
Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259
Score = 32.0 bits (71), Expect = 0.92
Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%)
Query: 194 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 244
P P + K P P+ + +E P KPP+P+ P Q PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309
Query: 245 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 299
P P RP P P P + N+ P ++ + P S E P +
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369
Query: 300 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 343
P R P P G + QL S + V G PPLP P A
Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%)
Query: 188 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 244
G +S P +SP G+ PVP +G EP +++ P+P + +KP +PP V +
Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 245 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 304
P P + +P + S P+ P +P SPG P
Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220
Query: 305 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 343
P PG + T GG + S +S PPLP P A
Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259
Score = 32.0 bits (71), Expect = 0.92
Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%)
Query: 194 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 244
P P + K P P+ + +E P KPP+P+ P Q PP
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309
Query: 245 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 299
P P RP P P P + N+ P ++ + P S E P +
Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369
Query: 300 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 343
P R P P G + QL S + V G PPLP P A
Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,180,621
Number of Sequences: 37866
Number of extensions: 1347216
Number of successful extensions: 7934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 675
Number of HSP's that attempted gapping in prelim test: 5449
Number of HSP's gapped (non-prelim): 2269
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.