BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] (389 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] 817 0.0 gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens] 817 0.0 gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens] 809 0.0 gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens] 772 0.0 gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens] 758 0.0 gi|157820785 SH2 domain containing 7 [Homo sapiens] 115 9e-26 gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] 96 7e-20 gi|21361891 SH2 domain containing 4A [Homo sapiens] 60 3e-09 gi|222537752 Src homology 2 domain containing transforming prote... 55 1e-07 gi|117320537 phospholipase C, gamma 2 [Homo sapiens] 52 1e-06 gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] 50 5e-06 gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] 50 5e-06 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 49 6e-06 gi|58219064 Src homology 2 domain containing E [Homo sapiens] 49 1e-05 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 48 1e-05 gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] 47 2e-05 gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] 47 2e-05 gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 45 1e-04 gi|111074524 Src homology 2 domain containing F [Homo sapiens] 45 1e-04 gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Ho... 45 1e-04 gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Ho... 45 1e-04 gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Ho... 45 1e-04 gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 44 2e-04 gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 44 2e-04 gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 44 3e-04 gi|19923345 RNA binding motif protein 12 [Homo sapiens] 44 3e-04 gi|23510462 RNA binding motif protein 12 [Homo sapiens] 44 3e-04 gi|242247193 SH2B adaptor protein 2 [Homo sapiens] 42 7e-04 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 42 7e-04 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 42 7e-04 >gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] Length = 389 Score = 817 bits (2110), Expect = 0.0 Identities = 389/389 (100%), Positives = 389/389 (100%) Query: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE Sbjct: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 Query: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR 120 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR Sbjct: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR 120 Query: 121 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE 180 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE Sbjct: 121 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE 180 Query: 181 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS 240 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS Sbjct: 181 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS 240 Query: 241 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA 300 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA Sbjct: 241 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA 300 Query: 301 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP 360 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP Sbjct: 301 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP 360 Query: 361 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 389 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ Sbjct: 361 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 389 >gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens] Length = 389 Score = 817 bits (2110), Expect = 0.0 Identities = 389/389 (100%), Positives = 389/389 (100%) Query: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE Sbjct: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 Query: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR 120 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR Sbjct: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVR 120 Query: 121 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE 180 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE Sbjct: 121 FSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGE 180 Query: 181 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS 240 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS Sbjct: 181 TLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPS 240 Query: 241 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA 300 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA Sbjct: 241 QLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEA 300 Query: 301 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP 360 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP Sbjct: 301 PSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPP 360 Query: 361 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 389 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ Sbjct: 361 AWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 389 >gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens] Length = 399 Score = 809 bits (2089), Expect = 0.0 Identities = 389/399 (97%), Positives = 389/399 (97%), Gaps = 10/399 (2%) Query: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE Sbjct: 1 MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAE 60 Query: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRR----------EAERLLE 110 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRR EAERLLE Sbjct: 61 EVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRRVRPPLSVTHREAERLLE 120 Query: 111 PKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHY 170 PKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHY Sbjct: 121 PKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHY 180 Query: 171 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQ 230 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQ Sbjct: 181 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQ 240 Query: 231 KEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFY 290 KEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFY Sbjct: 241 KEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFY 300 Query: 291 AMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQ 350 AMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQ Sbjct: 301 AMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQ 360 Query: 351 GPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 389 GPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPPQ Sbjct: 361 GPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPPQ 399 >gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens] Length = 371 Score = 772 bits (1993), Expect = 0.0 Identities = 368/368 (100%), Positives = 368/368 (100%) Query: 22 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 81 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT Sbjct: 4 STFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKT 63 Query: 82 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 141 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF Sbjct: 64 QAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHF 123 Query: 142 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 201 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE Sbjct: 124 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTE 183 Query: 202 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 261 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT Sbjct: 184 ESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYT 243 Query: 262 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 321 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV Sbjct: 244 IPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPV 303 Query: 322 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 381 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA Sbjct: 304 LRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQA 363 Query: 382 WLPLGPPQ 389 WLPLGPPQ Sbjct: 364 WLPLGPPQ 371 >gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens] Length = 361 Score = 758 bits (1958), Expect = 0.0 Identities = 361/361 (100%), Positives = 361/361 (100%) Query: 29 MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 88 MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ Sbjct: 1 MTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQ 60 Query: 89 HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 148 HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD Sbjct: 61 HGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRD 120 Query: 149 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 208 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK Sbjct: 121 GRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSK 180 Query: 209 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 268 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR Sbjct: 181 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 240 Query: 269 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 328 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR Sbjct: 241 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSR 300 Query: 329 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 388 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP Sbjct: 301 PVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPP 360 Query: 389 Q 389 Q Sbjct: 361 Q 361 >gi|157820785 SH2 domain containing 7 [Homo sapiens] Length = 451 Score = 115 bits (287), Expect = 9e-26 Identities = 52/119 (43%), Positives = 77/119 (64%) Query: 70 LQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFV 129 LQ WF +TQA ++LQ+GA P WFHGFITR++ E+LL K G +L+R S+ A ++ Sbjct: 26 LQELALKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYI 85 Query: 130 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLAR 188 L+YR CRHF++ QLR+ R+++ G+ +H+ L +L+ HY L P+ E LT R Sbjct: 86 LSYRGSDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPR 144 >gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] Length = 352 Score = 95.5 bits (236), Expect = 7e-20 Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%) Query: 77 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 136 WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++ Sbjct: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75 Query: 137 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 191 C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P Sbjct: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130 >gi|21361891 SH2 domain containing 4A [Homo sapiens] Length = 454 Score = 60.1 bits (144), Expect = 3e-09 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 9/130 (6%) Query: 71 QAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREA-ERLLEPKPQGCYLVRFSESAVTFV 129 Q RA +QKT WFHG +T ++A E LL G +L+R SE + Sbjct: 330 QLPLRAGYQKTS-------DTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA 382 Query: 130 LTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYG-ETLTEPLAR 188 L+Y S C+HFL+ D + + HA L DL+ ++ P++ G E L P + Sbjct: 383 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ 442 Query: 189 QTPEPAGLSL 198 Q P L L Sbjct: 443 QDQLPDYLEL 452 >gi|222537752 Src homology 2 domain containing transforming protein D [Homo sapiens] Length = 340 Score = 54.7 bits (130), Expect = 1e-07 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 6/102 (5%) Query: 95 WFHGFITRREAERLLEPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 153 WFHG + R +AE LL +G YLVR SE + L+ RS H A+ R+ + VV Sbjct: 240 WFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQ-VV 298 Query: 154 LGEDSA-HARLQDLLLHYTAHPLSPYGE---TLTEPLARQTP 191 LG+ S + +L+LHY++ PL G L P+ QTP Sbjct: 299 LGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP 340 >gi|117320537 phospholipase C, gamma 2 [Homo sapiens] Length = 1265 Score = 51.6 bits (122), Expect = 1e-06 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 4/88 (4%) Query: 89 HGAAPAWFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLR 147 H + P W++ ++R EAE +L P+ G +L+R E + ++ +T+R+R +H + R Sbjct: 641 HESKP-WYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRIN--R 697 Query: 148 DGRHVVLGEDSAHARLQDLLLHYTAHPL 175 DGRH VLG + L +L+ +Y H L Sbjct: 698 DGRHFVLGTSAYFESLVELVSYYEKHSL 725 >gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] Length = 1291 Score = 49.7 bits (117), Expect = 5e-06 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%) Query: 95 WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 153 W+H +TR +AE +L P+ G +LVR ++ +++R+ +H + Q +G+ V+ Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725 Query: 154 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 212 LG +S L DL+ +Y HPL Y + L P+ + E G T E ++G+ + Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778 Query: 213 NPQY 216 NP + Sbjct: 779 NPGF 782 >gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] Length = 1290 Score = 49.7 bits (117), Expect = 5e-06 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 11/124 (8%) Query: 95 WFHGFITRREAERLLEPKPQ-GCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVV 153 W+H +TR +AE +L P+ G +LVR ++ +++R+ +H + Q +G+ V+ Sbjct: 668 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQ--EGQTVM 725 Query: 154 LGEDSAHARLQDLLLHYTAHPLSPYGE-TLTEPLARQTPEPAGLSLRTEESNFGSKSQDP 212 LG +S L DL+ +Y HPL Y + L P+ + E G T E ++G+ + Sbjct: 726 LG-NSEFDSLVDLISYYEKHPL--YRKMKLRYPINEEALEKIG----TAEPDYGALYEGR 778 Query: 213 NPQY 216 NP + Sbjct: 779 NPGF 782 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 49.3 bits (116), Expect = 6e-06 Identities = 58/200 (29%), Positives = 75/200 (37%), Gaps = 29/200 (14%) Query: 171 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 229 T+ SP P + P P SL S S++ P + Q SPI Q P+P Sbjct: 1035 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1090 Query: 230 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 289 +K+P+Q L PK P P +P PP T P P RP P PS P +A Sbjct: 1091 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRP---PPPSGRSQPSPQAGLA- 1137 Query: 290 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQ------NTGGSQLHS 343 G G G + + + + A H R S R P Q + G + L Sbjct: 1138 ---GPGPAGYSTARPTIPPRAGVISAPQSH--ARASAGRLTPESQSKTSETSKGSTFLPE 1192 Query: 344 ENSVIGQGPPLPHQPPPAWR 363 PP PPPA R Sbjct: 1193 PLKPQAAFPPQSSLPPPAQR 1212 >gi|58219064 Src homology 2 domain containing E [Homo sapiens] Length = 495 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Query: 95 WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 153 W+HG I+R EAE L+P + YLVR SES + + + ++ C H ++AQ +D ++ Sbjct: 395 WYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKY-T 453 Query: 154 LGEDSAHARLQDLLLHYTAHPLSPY 178 L + SA ++HY ++ P+ Sbjct: 454 LNQTSAVFDSIPEVVHYYSNEKLPF 478 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 48.1 bits (113), Expect = 1e-05 Identities = 39/122 (31%), Positives = 51/122 (41%), Gaps = 19/122 (15%) Query: 171 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 229 T+ SP P + P P SL S S++ P + Q SPI Q P+P Sbjct: 1040 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1095 Query: 230 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAP-----RPKPSNPIYNEPD 284 +K+P+Q L PK P P +P PP T P P RP P P P+ + P Sbjct: 1096 ------QKDPAQPLEPKRPPPPRPVAPP---TRPAPPQRPPPPSGARSPAPTRKEFGAPK 1146 Query: 285 EP 286 P Sbjct: 1147 SP 1148 >gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] Length = 532 Score = 47.4 bits (111), Expect = 2e-05 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%) Query: 43 SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 94 SP A+ NT G+A R E P E E +AW +KT L A+ Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420 Query: 95 ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 141 WFHG I+R E++RL+ + G +LVR S+ + FVL+ +H+ Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480 Query: 142 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 176 L+ + + D R DLL H L+ Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515 >gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] Length = 532 Score = 47.4 bits (111), Expect = 2e-05 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 21/155 (13%) Query: 43 SPQAPEAASNT-------GNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPA- 94 SP A+ NT G+A R E P E E +AW +KT L A+ Sbjct: 361 SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTS 420 Query: 95 ----------WFHGFITRREAERLL--EPKPQGCYLVRFSE-SAVTFVLTYRSRTCCRHF 141 WFHG I+R E++RL+ + G +LVR S+ + FVL+ +H+ Sbjct: 421 LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY 480 Query: 142 LLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLS 176 L+ + + D R DLL H L+ Sbjct: 481 LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 515 >gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like [Homo sapiens] Length = 303 Score = 45.1 bits (105), Expect = 1e-04 Identities = 67/267 (25%), Positives = 106/267 (39%), Gaps = 60/267 (22%) Query: 94 AWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRHV 152 AW+ G ++R+EA+ L+ + G +LVR S + +VL+ + H+++ L + R Sbjct: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 Query: 153 VLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGL----SLRTEESNF--- 205 + ++ H L LL Y H L TL EP R P G +L T E N Sbjct: 73 IGDQEFDH--LPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYV 128 Query: 206 -------GSKSQDPNPQYSPIIKQGQAPVPMQKE-----GAGEKEPSQLLRPKPPIPAKP 253 G+ ++D K+G+ V ++K A K+ + P P + Sbjct: 129 RTLYDFPGNDAEDLP------FKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLV 182 Query: 254 QLPP---------EVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 304 + P Y IP P H A +P+ + P+ GSPG A + Sbjct: 183 RSSPHGKHGNRNSNSYGIPEPAHAYA-QPQTTTPL-----------PAVSGSPGAAIT-- 228 Query: 305 YVEVEDEGLPATLGHPVLRKSWSRPVP 331 LP+T PV K+ + VP Sbjct: 229 -------PLPSTQNGPVFAKAIQKRVP 248 >gi|111074524 Src homology 2 domain containing F [Homo sapiens] Length = 423 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Query: 95 WFHGFITRREAERLLEPKPQGCYLVRFSESAVT-FVLTYRSRTCCRHFLLAQLRDGRHVV 153 W+HG I+R +AE LL + YLVR SE++ F L+ +S H L++ ++ ++V+ Sbjct: 323 WYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVL 382 Query: 154 LGEDSAHARLQDLLLHYTAHPLSPYGE---TLTEPLARQT 190 + + +++ HY + L G +L P+A +T Sbjct: 383 GQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRT 422 >gi|57863248 zinc finger, CCHC domain containing 11 isoform a [Homo sapiens] Length = 1645 Score = 44.7 bits (104), Expect = 1e-04 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%) Query: 184 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 237 + +A + S+RT +S+ S+S +PQ P + P + G+ K Sbjct: 1399 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1458 Query: 238 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 286 P Q +P + P+ PQ PP Y+ P H P P PS PI+ P Sbjct: 1459 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1511 Query: 287 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 339 + +PG APSNI + + P + + W R V P G+ Sbjct: 1512 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1566 Query: 340 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 373 +SE G PP+P H P P +W + L N Q Sbjct: 1567 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1609 >gi|57863246 zinc finger, CCHC domain containing 11 isoform b [Homo sapiens] Length = 1644 Score = 44.7 bits (104), Expect = 1e-04 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%) Query: 184 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 237 + +A + S+RT +S+ S+S +PQ P + P + G+ K Sbjct: 1398 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1457 Query: 238 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 286 P Q +P + P+ PQ PP Y+ P H P P PS PI+ P Sbjct: 1458 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1510 Query: 287 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 339 + +PG APSNI + + P + + W R V P G+ Sbjct: 1511 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1565 Query: 340 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 373 +SE G PP+P H P P +W + L N Q Sbjct: 1566 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1608 >gi|57863250 zinc finger, CCHC domain containing 11 isoform c [Homo sapiens] Length = 1640 Score = 44.7 bits (104), Expect = 1e-04 Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 45/223 (20%) Query: 184 EPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPV----PMQKEGAGEK-- 237 + +A + S+RT +S+ S+S +PQ P + P + G+ K Sbjct: 1394 QQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAITQPSSQPGSQPKLG 1453 Query: 238 EPSQLLRP----KPPIPAKPQLPPEVYTIPVPRH-------RPAPRPKPSNPIYNEPDEP 286 P Q +P + P+ PQ PP Y+ P H P P PS PI+ P Sbjct: 1454 PPQQGAQPPHQVQMPLYNFPQSPPAQYS---PMHNMGLLPMHPLQIPAPSWPIHG----P 1506 Query: 287 IAFYAMGRGSPGEAPSNI------YVEVEDEGLPATLGHPVLRKSWSRPV-PGGQNTGGS 339 + +PG APSNI + + P + + W R V P G+ Sbjct: 1507 VI-----HSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNSLVNSGA 1561 Query: 340 QLHSENSVIGQGPPLP--HQP-------PPAWRHTLPHNLSRQ 373 +SE G PP+P H P P +W + L N Q Sbjct: 1562 VGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQ 1604 >gi|237757310 synaptojanin 1 isoform a [Homo sapiens] Length = 1612 Score = 44.3 bits (103), Expect = 2e-04 Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%) Query: 171 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 229 T+ SP P + P P SL S S++ P + Q SPI Q P+P Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134 Query: 230 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 289 QK+ A EP + P+P P PP+ P PAP K I P +A Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194 Query: 290 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 349 M EAP + +D P + + P P G +T + VI Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244 Query: 350 QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 384 P H A R T P + S+ +G +LP Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277 >gi|237757308 synaptojanin 1 isoform b [Homo sapiens] Length = 1350 Score = 44.3 bits (103), Expect = 2e-04 Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 17/215 (7%) Query: 171 TAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDP-NPQYSPIIKQGQAPVPM 229 T+ SP P + P P SL S S++ P + Q SPI Q P+P Sbjct: 1079 TSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLP- 1134 Query: 230 QKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAF 289 QK+ A EP + P+P P PP+ P PAP K I P +A Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194 Query: 290 YAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIG 349 M EAP + +D P + + P P G +T + VI Sbjct: 1195 REM------EAPKSPGTTRKDN---IGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI- 1244 Query: 350 QGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLP 384 P H A R T P + S+ +G +LP Sbjct: 1245 -SAPQSHARASAGRLT-PESQSKTSETSKGSTFLP 1277 >gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] Length = 330 Score = 43.5 bits (101), Expect = 3e-04 Identities = 38/171 (22%), Positives = 70/171 (40%), Gaps = 12/171 (7%) Query: 93 PAWFHGFITRREAERLLEPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGRH 151 P WFH ++R +AE LL K G +++R S+S+ F ++ R +HF + + G + Sbjct: 56 PKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115 Query: 152 VVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESN----FGS 207 + E L L+ +Y + +S + R+ G SL G+ Sbjct: 116 FLWTE--KFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGA 173 Query: 208 KSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPE 258 ++ P + + +P+Q+ + P P P + Q PP+ Sbjct: 174 VGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQY-----APAPQQLQQPPQ 219 >gi|19923345 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%) Query: 245 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 304 P PPIPA P LPP P+P P P P P+ P P P P Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237 Query: 305 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 358 LP G P L P+P G N G+ ++ N++ + GP P P Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285 Score = 30.4 bits (67), Expect = 2.8 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%) Query: 209 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 268 S P P PI PVP P L P PP+P P +P VP Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236 Query: 269 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 304 P P P+ P P+ G G+P +N+ Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272 >gi|23510462 RNA binding motif protein 12 [Homo sapiens] Length = 932 Score = 43.5 bits (101), Expect = 3e-04 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%) Query: 245 PKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 304 P PPIPA P LPP P+P P P P P+ P P P P Sbjct: 189 PIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVP--------SVPPMTP--- 237 Query: 305 YVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSV--IGQGPPLPHQP 358 LP G P L P+P G N G+ ++ N++ + GP P P Sbjct: 238 --------LPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNP 285 Score = 30.4 bits (67), Expect = 2.8 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 21/96 (21%) Query: 209 SQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHR 268 S P P PI PVP P L P PP+P P +P VP Sbjct: 198 SLPPMPSIPPI------PVP---------PPVPTLPPVPPVPPIPPVP------SVPPMT 236 Query: 269 PAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNI 304 P P P+ P P+ G G+P +N+ Sbjct: 237 PLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNL 272 >gi|242247193 SH2B adaptor protein 2 [Homo sapiens] Length = 675 Score = 42.4 bits (98), Expect = 7e-04 Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 25/190 (13%) Query: 95 WFHGFITRREAERLL---EPKPQGCYLVRFSESAV-TFVLTYRSRTCCRHFLLAQLRDGR 150 WFHG ++R +A +L+ P+ G +++R SE+ +VLT+ + +H L+ G+ Sbjct: 460 WFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQ 519 Query: 151 -HVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKS 209 HV + + D+L H+ HP+ PL ++ A ++LR+ ++ Sbjct: 520 CHV---QHLWFQSVLDMLRHFHTHPI---------PL--ESGGSADITLRSY-----VRA 560 Query: 210 QDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRP 269 QDP P+ P A + G+ S L P PA P + Sbjct: 561 QDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACP-PASPSDAAGASSSSASSSSA 619 Query: 270 APRPKPSNPI 279 A P P P+ Sbjct: 620 ASGPAPPRPV 629 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.4 bits (98), Expect = 7e-04 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%) Query: 206 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 262 G +S P +SP G+ PVP +G EP +++ P+P + +KP +PP V + Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190 Query: 263 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 322 P P + +P + S P+ P +P SPG P Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220 Query: 323 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 361 P PG + T GG + S +S PPLP P A Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259 Score = 32.0 bits (71), Expect = 0.98 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%) Query: 212 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 262 P P + K P P+ + +E P KPP+P+ P Q PP Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309 Query: 263 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 317 P P RP P P P + N+ P ++ + P S E P + Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369 Query: 318 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 361 P R P P G + QL S + V G PPLP P A Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 42.4 bits (98), Expect = 7e-04 Identities = 44/165 (26%), Positives = 64/165 (38%), Gaps = 46/165 (27%) Query: 206 GSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEP--SQLLRPKPPIPAKP-QLPPEVYTI 262 G +S P +SP G+ PVP +G EP +++ P+P + +KP +PP V + Sbjct: 132 GGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190 Query: 263 PVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVL 322 P P + +P + S P+ P +P SPG P Sbjct: 191 PRP-IQSSPHNRGSPPVPGGPRQP---------SPGPTPP-------------------- 220 Query: 323 RKSWSRPVPGGQNT--GGSQLH----SENSVIGQGPPLPHQPPPA 361 P PG + T GG + S +S PPLP P A Sbjct: 221 ------PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259 Score = 32.0 bits (71), Expect = 0.98 Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 30/176 (17%) Query: 212 PNPQYSPIIKQGQAPVPMQKEGAGEKE---PSQLLRPKPPIPAKP------QLPPEVYTI 262 P P + K P P+ + +E P KPP+P+ P Q PP Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP---- 309 Query: 263 PVPRHRPAPRPKPSNPIYNE-----PDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATL 317 P P RP P P P + N+ P ++ + P S E P + Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPV 369 Query: 318 GHPVLRKSWSRPVPGGQNTGGS--------QLHSENSV----IGQGPPLPHQPPPA 361 P R P P G + QL S + V G PPLP P A Sbjct: 370 RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.134 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,995,769 Number of Sequences: 37866 Number of extensions: 1391833 Number of successful extensions: 8015 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 158 Number of HSP's successfully gapped in prelim test: 676 Number of HSP's that attempted gapping in prelim test: 5528 Number of HSP's gapped (non-prelim): 2272 length of query: 389 length of database: 18,247,518 effective HSP length: 104 effective length of query: 285 effective length of database: 14,309,454 effective search space: 4078194390 effective search space used: 4078194390 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.